Typing tool
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Typing tool
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Complete norovirus genomes
| MW305514 | GII.9 | |
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| GII.P7 |
ORF1: 1..5063
ORF2: 5044..6657
ORF3: 6657..7421
LOCUS MW305514 7459 bp RNA linear VRL 06-JUL-2021
DEFINITION Norovirus GII isolate PNV008798 nonstructural polyprotein (ORF1)
gene, partial cds; and VP1 (ORF2) and VP2 (ORF3) genes, complete
cds.
ACCESSION MW305514
VERSION MW305514.1
KEYWORDS .
SOURCE Norovirus GII
ORGANISM Norovirus GII
Viruses; Riboviria; Orthornavirae; Pisuviricota; Pisoniviricetes;
Picornavirales; Caliciviridae; Norovirus; Norwalk virus.
REFERENCE 1 (bases 1 to 7459)
AUTHORS Tohma,K., Lepore,C.J., Martinez,M., Degiuseppe,J.I., Khamrin,P.,
Saito,M., Mayta,H., Nwaba,A., Ford-Siltz,L.A., Galeano,M.E.,
Zimic,M., Stupka,J.A., Gilman,R.H., Maneekarn,N., Ushijima,H.,
Green,K.Y. and Parra,G.I.
TITLE Genome-wide analyses of human noroviruses reveal coexistence of
viral populations evolving under recombination constraints
JOURNAL Unpublished
REFERENCE 2 (bases 1 to 7459)
AUTHORS Tohma,K., Lepore,C.J., Martinez,M., Degiuseppe,J.I., Khamrin,P.,
Saito,M., Mayta,H., Nwaba,A., Ford-Siltz,L.A., Galeano,M.E.,
Zimic,M., Stupka,J.A., Gilman,R.H., Maneekarn,N., Ushijima,H.,
Green,K.Y. and Parra,G.I.
TITLE Direct Submission
JOURNAL Submitted (23-NOV-2020) CBER/OVRR/DVP/LHV, U.S. Food and Drug
Administration, 10903 New Hampshire Avenue, Silver Spring, MD
20993, USA
COMMENT ##Assembly-Data-START##
Assembly Method :: High-performance Integrated Virtual
Environment (HIVE) v. 2
Sequencing Technology :: Illumina
##Assembly-Data-END##
FEATURES Location/Qualifiers
source 1..7459
/organism="Norovirus GII"
/mol_type="genomic RNA"
/isolate="PNV008798"
/isolation_source="feces"
/host="Homo sapiens"
/db_xref="taxon:122929"
/country="Peru"
/collection_date="30-Jul-2008"
/note="genotype: GII.9[GII.P7]"
gene <1..5063
/gene="ORF1"
CDS <1..5063
/gene="ORF1"
/codon_start=3
/product="nonstructural polyprotein"
/protein_id="QPJ58878.1"
/translation="FGSQNSVNDSTNTAPSDKEEVGAFSNIKVGFKKMLGVVPKGTKA
PNSEQHCPTVKIGTRTLAVPPEPPNGEDTVQFDAKSETVRGLPDLTTVQNEHENTPYT
VPPLSEREHRPATEPLPGTILEMWDGEFYHYSVYVSGGKALGVHKPPAAISLATIELT
PISLYWRPVYTPNYLVCPDTLKGLAGEKFPYTAFSNNCYNFCCWVLELNDTWLSRRSI
SRTTGFFKPYQSWNRKPLPTVDDGKIKKVANAILCALGSLFSKPIKDLLGKLKPLNLL
HLLASCDWTFAGVVETVILMAELFNVFWTPPDVSNFIASLIGDFELQGPEDLAVELVP
VVMGGIGMVLGFTAEKIGRMLSSAASTLRACKDLGNYALDILKLVMKWFFPKKEEKAE
METLRAIEDAVLDMEAIGNNHLTTLLKDKDSLTAFMKTLDLEEEKARKLSTKSSSPDI
VGTINAILARIAAARSLLHKAKEEMFSRIRPVVVMISGRPGIGKTHMARHLAKSIANT
MSGDQRVGLVPRNGVDHWDAYRGERVVLWDDYGMGNPVKDALTLQELADTCPVTLNCD
RIENKGKMFDSDVIIITTNLVNPAPLDYVNFEACSRRVDFLVYAESPEIEKVKRDFPG
QPDMWKDHFKPDFSHIKLTLAPQGGFDKNGNTPHGKGTMRSLTQGSLTARVAGLVHER
RDEFQLQGNDLQIYNFDTNRVSAFRKLAADNKYGIMETMRVGAALKNVKTLEDLKVAL
RDVKFNECEIIYKSSKYRVSSNGKGSVSVDKVEDQASQTANEVGSALLRLRQARARYY
VSCFQDLVYTLIQVAGASFVVNRISKRFCWERWVKPTETQETSDSEKEAAQGRWEIEP
KDTEPEGKKGKNKKGRGKKHTAFSSKGLSDEEYDEFKRIREERNGKYSIEEYLQDRDR
YYEEVAVARATEEDFCEEEEAKIRQRIFRPTKKQRKEERGVLGLVTGSDIRKRRPDDF
QPKGNLWADDTRSVDYNERLDFEAPPSVWSRIVPLGTGWGFWVSSNLLITTTHVLPKG
IKELFGVEIKQIQIHKSGEFCRFRFPRPIRPDVTGLVLEEGAPEGTVCSILVKRPTGE
MIPLAVRMGTHASMKIQGRTVGGQMGMLLTGANAKNMDLGTGPGDCGCPYIYKRGNDI
VVAGVHTAAARGGNTVICATQGQDGEAVLEGNENLGTYCGAPILGPGKAPKLSTKTKF
WRSSPDALPPGTYEPAYLGGKDPRVEKGPSLQQVMRDQLKPFTEPRGKPPRPAVLEEA
KKTVMNVLEQTIDPAKPWTYSQACASLDKTTSSGSPHHVRKNDHWNGESFTGPLADQA
SKANLMYEQAKHVQPVYTAALKDELVKTDKIYKKIKKRLLWGSDLGTMIRCARAFGGL
MDSMKASCIALPCRVGMNMNEDGPIIFDKHSKYRYHYDADYSRWDSTQQRSILTAAME
VMVRFSAEPELAQVVAEDLLAPSQLDVGDFVISVQEGLPSGVPCTSQWNSIAHWILTL
SAMAEVSGLSPDVVQAHSCFSFYGDDEIVSTDINLDPMKLTQKLREYGLVPTRPDKTE
GPLVITEDLTGLTFLRRSIARDPAGWFGKLDQDSILRQLYWTRGPNHENPYESMVPHS
QRATQLMALLGEASLHGPQFYKKVSKMVINEIKSGGLEFYVPRQEAMFRWMRFSDLST
WEGDRNLAPEGVNEDGVE"
mat_peptide <1..971
/gene="ORF1"
/product="p48"
mat_peptide 972..2069
/gene="ORF1"
/product="NTPase"
mat_peptide 2070..2588
/gene="ORF1"
/product="p22"
mat_peptide 2589..2987
/gene="ORF1"
/product="VPg"
mat_peptide 2988..3530
/gene="ORF1"
/product="Pro"
mat_peptide 3531..5060
/gene="ORF1"
/product="RdRp"
gene 5044..6657
/gene="ORF2"
CDS 5044..6657
/gene="ORF2"
/note="major capsid protein"
/codon_start=1
/product="VP1"
/protein_id="QPJ58879.1"
/translation="MKMASNDAAPSSDGAAGLVPEINHEVMAIEPVAGASIAAPVVGQ
QNIIDPWIRNNFVQAPAGEFTVSPRNAPGEFLLDLELGPDLNPYLAHLARMYNGHAGG
MEVQIVLAGNAFTAGKILFAVIPPGFPYENLSPAQLTMCPHVVVDVRQLEPVMLPMPD
IRNTFFHYNQDGGPKLRLIAMLYTPLRANNSGDDVFTVSCRVLTRPAPDFEFTFLVPP
SVESKTKAFTIPVLKISEMTNSRFPVPVDQMYTSRSEGIVVQPQNGRATIDGELLGTT
LVSPVSVCNFKGNLQTEVPGERQLYQLQLTNLDGSPIDPTDDTPGPLGCPDFTGLLYG
VASQRGPGDTTRAHEARIDTGNGTYAPKIGQVRFYSTSNNFEVNQPTHFTPVGIYIEG
NSSDFNQWQLPRYGGHLANNNHLAPAVSPLFPGEQILFFRSFIPGASGHTNGEMDCLL
PQEFVQHFYQEAATAQSEVALLRFVNPDTGRVLFESKLHKQGFMTIASSGDHPIIMPT
NGYFRFEAWVNQFYSLAPVGTGSGRRRIQ"
gene 6657..7421
/gene="ORF3"
CDS 6657..7421
/gene="ORF3"
/note="minor structural protein; small basic protein"
/codon_start=1
/product="VP2"
/protein_id="QPJ58880.1"
/translation="MAGAFIAGLAGDVLSSGVGSLVNAGSNAINQNVEYNFNRQLQEA
SFKHDKEMLNAQIAATTQLQKDIMAIKQGVLSAGGFSPTDAARGSVGAPMTKILDWNG
SRYWAPNSMRTTGYSGNFTSQGVRQVFQPQGTLNPSTLKNVPKAPSSVSSLSTQSTQS
TKLSGSTAGTSIPSSRTTTLSRTSEWVRGQNERLSPFMSGALQTTFVTPPSSKSSSAG
TVSTVPKEVLDSWTPVFNTRRQPLFAHVRRRGESQI"
ORIGIN
1 cctttggcag ccaaaactct gtcaatgaca gtaccaacac cgccccttct gataaagaag
61 aggttggtgc attctccaat attaaagttg gattcaagaa aatgctgggt gtcgtcccca
121 aggggaccaa agcacccaat agtgagcagc actgccccac agttaagatc gggaccagaa
181 cactagcggt tccccctgag cccccaaatg gtgaagacac cgtgcagttt gatgcgaagt
241 cagaaactgt gcgtgggtta ccagacctaa caacggtgca gaatgaacac gaaaacacac
301 catacactgt ccccccattg agtgaaaggg aacacagacc agccactgag ccgcttcctg
361 gaacaatact agagatgtgg gatggtgaat tctaccacta ctccgtgtac gtcagcggcg
421 gcaaagccct aggggttcac aagcccccag cagcaataag cctcgcgacg atagagctca
481 cccccatatc cctttactgg agacctgttt acacccccaa ctacctggtc tgcccagaca
541 cgctgaaggg ccttgctggt gagaagtttc cctatacagc cttcagtaac aactgttaca
601 acttctgttg ctgggtgctt gagctcaatg acacgtggct tagcagaaga agcatctcca
661 gaactaccgg cttcttcaaa ccatatcagt cttggaatag gaaacccctt ccaaccgttg
721 atgatggaaa gattaaaaag gtggctaatg caatcctctg tgctcttgga tcactgtttt
781 caaagccaat caaagacctg ttgggcaagc ttaaaccact gaacttactg cacctgctcg
841 catcatgcga ctggacgttt gcgggtgtag tggagacagt catactaatg gcggagcttt
901 tcaacgtctt ttggacaccg ccagatgtct ccaacttcat agcctccctg ataggtgatt
961 ttgaattgca aggtcctgag gacctggctg tggagcttgt tcctgtggtc atgggtggca
1021 taggaatggt cctcggcttc actgccgaga agataggccg catgctgtcg tccgctgcat
1081 caacactgcg ggcatgcaaa gacctaggaa actatgcact tgacatactc aaacttgtta
1141 tgaagtggtt cttcccaaag aaagaggaaa aagccgagat ggaaaccttg agggcgattg
1201 aggatgccgt cctggacatg gaagccatag ggaacaacca tctcacaacc ctcctcaagg
1261 acaaggatag cctcacggct ttcatgaaga ctctggactt ggaagaggag aaggcgagga
1321 aactgtccac caaatcgtcc tcgccagaca tcgttggcac tatcaacgcc atactggcca
1381 ggatagctgc tgccagatcc ctcctacaca aggccaaaga agaaatgttc agcaggatca
1441 gaccggtggt tgttatgatc tcaggcaggc ctggcattgg caaaacccat atggcaagac
1501 acttggctaa gagcatcgcc aacaccatga gtggcgacca gagagttggg ctcgtcccgc
1561 gcaatggggt cgaccactgg gacgcctaca ggggagagag ggtggtcttg tgggatgact
1621 atggcatggg aaaccctgtc aaagatgctc taacactgca agagttggcc gacacctgcc
1681 cggtcaccct aaactgtgat aggattgaga acaaggggaa gatgttcgac agtgatgtca
1741 ttataatcac gaccaatcta gtcaacccgg cgcccctcga ctatgtgaac ttcgaggcgt
1801 gttctagaag ggttgacttt ttggtctatg cagagtcacc agaaattgag aaggttaaaa
1861 gagatttccc cggtcaacct gatatgtgga aggaccattt taagccagac ttctcccata
1921 taaagctgac tctagccccc caaggcggat ttgacaagaa tggcaacacc ccgcatggca
1981 agggcaccat gcgatctcta acccaggggt ccctgactgc aagggttgca ggtcttgttc
2041 atgagaggag agatgagttt cagctccaag ggaacgacct ccaaatatac aactttgaca
2101 ccaacagagt ctccgcattt aggaaactgg ccgcagacaa caagtatggg atcatggaaa
2161 caatgagagt gggtgcggca ctcaagaatg tcaagacttt ggaagatctg aaagttgccc
2221 tgagggatgt gaagttcaac gagtgtgaaa taatttacaa gagctccaaa tatcgcgtct
2281 cttccaacgg taaaggttct gtctctgttg ataaggttga ggaccaagca tcccagactg
2341 caaatgaggt gggttcagct cttcttagac tcaggcaagc aagggccaga tactacgtca
2401 gctgctttca agacctcgtc tacacgctaa tacaggttgc cggagcgtca ttcgttgtta
2461 acaggatctc caagaggttt tgttgggaga gatgggtcaa accgaccgag acccaggaaa
2521 cgagtgactc cgaaaaggaa gcagcccaag gtagatggga gatcgaaccc aaggacacag
2581 agccagaggg taagaagggc aagaacaaga aaggaagggg taagaaacac acagctttct
2641 ccagcaaggg cctgagtgat gaagagtatg acgagtttaa gagaattagg gaagaaagga
2701 acgggaaata ctccattgag gaatacctgc aagatcggga ccgctactat gaggaggtgg
2761 cagtcgcccg ggcaacagag gaagacttct gtgaagagga ggaggccaag ataaggcaga
2821 gaatcttccg ccctacaaag aaacagagga aggaagaaag gggggtgctt ggtctggtca
2881 ctggctcaga catcaggaag aggagaccag acgatttcca accaaagggc aacctgtggg
2941 cagatgacac caggagtgtg gactataacg agagacttga tttcgaggct cccccgagtg
3001 tctggtcgag aatagtccca ctgggcactg gatggggctt ctgggtctca tccaacctct
3061 tgatcacgac aacacacgtc ctgcctaaag ggattaagga actttttggg gttgaaatca
3121 aacagatcca aatccataag tctggagagt tttgcaggtt caggttccca agaccaatca
3181 ggccagatgt cacggggctc gtgttggagg aaggtgcccc agaaggcact gtctgttcca
3241 tactcgtaaa gagacccaca ggtgagatga tccccttggc agtgaggatg ggcacacatg
3301 catccatgaa aatacagggt agaaccgtcg gtggccagat gggaatgctt ctcacagggg
3361 caaacgcgaa gaacatggat cttggcaccg gtcctggtga ctgtggttgt ccctacatct
3421 acaaacgtgg caatgacata gttgtcgcgg gtgtccacac cgcagcagcc cggggaggca
3481 acactgttat atgtgccaca caggggcaag atggggaggc agtccttgag ggaaatgaaa
3541 accttggcac ttattgcggt gccccaattt tgggtcctgg caaggcgccc aaactcagca
3601 cgaagaccaa attctggcgc tcatcaccag acgctttgcc gccaggcact tatgaacctg
3661 cctacctggg aggcaaggac cccagagtag agaaagggcc atccctgcag caagtcatga
3721 gagatcaact aaaacctttc acagaaccca ggggcaagcc acctagacct gcagtcttag
3781 aagaagccaa aaagacagtg atgaatgttc tagaacaaac catcgaccct gccaagccat
3841 ggacttactc ccaagcatgt gcctcactgg acaagaccac ttccagtggt agcccccatc
3901 atgtcaggaa aaatgaccat tggaacggag aatccttcac cggccccctt gcagatcaag
3961 catccaaagc caaccttatg tatgaacagg ccaaacatgt gcagcccgtg tacacggccg
4021 cgctcaaaga cgagcttgtc aagaccgaca agatctacaa aaagataaag aaaaggctct
4081 tatgggggtc ggatcttggc acgatgatca ggtgcgccag ggcctttggc ggtctcatgg
4141 atagcatgaa ggcaagttgt atagccctcc catgcagggt gggaatgaac atgaatgagg
4201 atggtcccat catatttgac aaacactcta agtacaggta ccactatgac gcagactact
4261 ccaggtggga ttcgactcaa caaaggagca ttctcacagc cgccatggaa gtgatggtgc
4321 gattctctgc cgaaccagaa ctggcacaag tggttgcaga ggaccttctg gctcccagtc
4381 aactagatgt tggcgatttt gtcatctcag tccaggaggg tctgccatcg ggggtcccat
4441 gcacatcaca atggaactca atagcacatt ggatcctaac tttgagtgca atggcagaag
4501 tgtcaggtct ctcaccagat gttgtccaag cccactcctg tttctcgttt tacggcgacg
4561 atgagatcgt cagcactgat atcaatcttg accccatgaa gttaacacag aaactcaggg
4621 agtatgggct ggtccccacc cgacctgaca aaactgaagg tcctctcgta ataactgaag
4681 acctcaccgg cctaacgttc ctgcgtaggt cgattgcacg agacccagct gggtggtttg
4741 gaaagttgga ccaagactca atccttaggc agttatactg gacaaggggc cccaaccatg
4801 agaatccata cgagagcatg gtccctcatt ctcagcgggc cacacaactt atggcccttc
4861 ttggtgaggc ttcgctgcat ggtccccagt tttataagaa agttagcaag atggtcatca
4921 atgaaattaa gagtggtggt ctggaatttt atgtgcccag acaagaggcc atgttcagat
4981 ggatgagatt ttctgacctc agcacatggg agggtgatcg caatcttgct cccgagggtg
5041 tgaatgaaga tggcgtcgaa tgacgcagct ccatcgagtg atggcgcggc cggcctcgtc
5101 ccagagatca atcatgaggt tatggcaatc gagcctgtcg caggtgcatc aatcgctgct
5161 cctgtggtgg gacaacaaaa tattattgat ccctggataa gaaacaattt tgtacaggca
5221 cctgctggag aatttactgt ttcccctagg aatgccccag gtgagttctt gcttgattta
5281 gaattaggtc ctgatttgaa cccctatctg gcacatttgg caagaatgta caacggtcat
5341 gcgggtggta tggaagtgca aatagtacta gctgggaatg cgttcacagc tggtaaaatc
5401 ctgttcgccg tcataccgcc tggatttccg tatgaaaact tgtccccagc acaactcacg
5461 atgtgccccc acgtcgtggt tgatgtaagg cagcttgagc ctgtcatgct gcccatgcca
5521 gacattagga atacattctt tcattataat caagatggtg ggccaaaatt gaggttgatt
5581 gctatgctgt atacccctct aagagctaat aattcaggtg atgatgtgtt cactgtttcc
5641 tgtagggttc ttacaaggcc tgcccctgat tttgaattta catttttagt tcccccctct
5701 gttgaatcaa agactaaggc attcaccatc ccagtgctta aaatttctga aatgactaat
5761 tcaagattcc ctgtaccagt tgaccagatg tacaccagca ggagtgaggg gatcgtggtt
5821 caacctcaga acggtagggc cacaattgac ggagagctac ttggcactac tctcgtctct
5881 ccagtctctg tgtgcaattt caagggaaac ttgcaaactg aggtcccagg tgaacgccag
5941 ctttaccaac tgcagctgac caacctcgat ggttcaccta tcgaccccac tgatgacaca
6001 cctgggccac taggctgtcc agacttcact ggcctcctct acggggttgc cagccagcgt
6061 ggtccaggtg acactacgcg ggcccatgag gcacggattg acaccggcaa tggtacttat
6121 gctcccaaaa ttggtcaggt caggttctat tcaacttcaa acaattttga agtaaaccaa
6181 cccacacact ttaccccagt gggaatctat attgagggca attcttctga ttttaatcaa
6241 tggcaactcc ccaggtatgg gggtcatcta gctaataaca accatttggc acccgcagtt
6301 tctccccttt ttcctggaga gcaaattctt ttctttagat ctttcatccc aggagccagt
6361 ggtcacacaa atggagagat ggattgtctc ctgcctcagg agtttgtgca gcacttctac
6421 caggaagcgg caactgcgca gtcagaagtg gccttactga ggtttgtcaa ccctgacact
6481 ggaagggttt tgtttgagtc caaactccac aagcaaggat tcatgacaat tgcaagttca
6541 ggtgatcatc ccatcatcat gccaactaat ggttatttta gatttgaagc ttgggttaac
6601 caattttact ctctcgcccc tgtgggaact ggaagtgggc gcagaaggat ccaataatgg
6661 ctggagcttt tatagcagga ttggccgggg acgttctgtc ctctggcgtt ggttcgctag
6721 tcaacgcggg ttccaacgct atcaaccaaa atgttgaata caatttcaac aggcaactcc
6781 aggaagcatc tttcaaacat gataaggaaa tgctcaatgc ccagattgct gcgacaacgc
6841 agctgcaaaa agacataatg gcaataaagc agggggtttt gtccgctggc ggcttttccc
6901 caactgatgc cgcgagaggt tcagtggggg cccctatgac caaaatctta gattggaatg
6961 gatcaagata ttgggctcca aattcaatga ggaccactgg ctactctggc aacttcactt
7021 cccaaggtgt taggcaagtg tttcagcctc aaggcactct taacccaagt actttgaaga
7081 atgttcccaa ggctccctcc tcagtaagtt ctcttagcac ccaatctacc caatcaacaa
7141 aattaagtgg ctccacagca ggaacctcta ttccctcatc cagaaccact acactttcaa
7201 gaaccagtga gtgggtgaga ggacagaatg aaagacttag ccctttcatg agtggcgcgc
7261 tacaaacaac gttcgtgacg ccaccatcaa gcaagtcttc ttctgcaggg acagtctcga
7321 ccgtccctaa ggaggttttg gactcctgga cgcctgtctt caatacacgc aggcagccac
7381 tcttcgccca cgttcgtagg cgaggggagt cacagattta gtgaaaagaa tgatttgaat
7441 ttgattctct attctgttc
//