Typing tool
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Typing tool
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Complete norovirus genomes
| MW305505 | GI.6 | |
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| GI.P6 |
ORF1: 1..5251
ORF2: 5235..6857
ORF3: 6857..7456
LOCUS MW305505 7456 bp RNA linear VRL 13-APR-2022
DEFINITION Norovirus GI isolate 11694 nonstructural polyprotein (ORF1) gene,
partial cds; VP1 (ORF2) gene, complete cds; and VP2 (ORF3) gene,
partial cds.
ACCESSION MW305505
VERSION MW305505.1
KEYWORDS .
SOURCE Norovirus GI
ORGANISM Norovirus GI
Viruses; Riboviria; Orthornavirae; Pisuviricota; Pisoniviricetes;
Picornavirales; Caliciviridae; Norovirus; Norwalk virus.
REFERENCE 1 (bases 1 to 7456)
AUTHORS Tohma,K., Lepore,C.J., Martinez,M., Degiuseppe,J.I., Khamrin,P.,
Saito,M., Mayta,H., Nwaba,A.U.A., Ford-Siltz,L.A., Green,K.Y.,
Galeano,M.E., Zimic,M., Stupka,J.A., Gilman,R.H., Maneekarn,N.,
Ushijima,H. and Parra,G.I.
TITLE Genome-wide analyses of human noroviruses provide insights on
evolutionary dynamics and evidence of coexisting viral populations
evolving under recombination constraints
JOURNAL PLoS Pathog 17 (7), e1009744 (2021)
PUBMED 34255807
REMARK Publication Status: Online-Only
REFERENCE 2 (bases 1 to 7456)
AUTHORS Tohma,K., Lepore,C.J., Martinez,M., Degiuseppe,J.I., Khamrin,P.,
Saito,M., Mayta,H., Nwaba,A., Ford-Siltz,L.A., Galeano,M.E.,
Zimic,M., Stupka,J.A., Gilman,R.H., Maneekarn,N., Ushijima,H.,
Green,K.Y. and Parra,G.I.
TITLE Direct Submission
JOURNAL Submitted (23-NOV-2020) CBER/OVRR/DVP/LHV, U.S. Food and Drug
Administration, 10903 New Hampshire Avenue, Silver Spring, MD
20993, USA
COMMENT ##Assembly-Data-START##
Assembly Method :: High-performance Integrated Virtual
Environment (HIVE) v. 2
Sequencing Technology :: Illumina
##Assembly-Data-END##
FEATURES Location/Qualifiers
source 1..7456
/organism="Norovirus GI"
/mol_type="genomic RNA"
/isolate="11694"
/isolation_source="feces"
/host="Homo sapiens"
/db_xref="taxon:122928"
/country="Japan"
/collection_date="28-Feb-2013"
/note="genotype: GI.6[GI.P6]"
gene <1..5251
/gene="ORF1"
CDS <1..5251
/gene="ORF1"
/codon_start=2
/product="nonstructural polyprotein"
/protein_id="QPJ58851.1"
/translation="NTKPIKIENTQMALGLLSREPSPSPNRGPPKQQRDRAPRNVAET
QQAMGWTDPPVDQNLPTWEELSQSEKQKIIAENSKWFDAGGLGPATLPSNYCRVQDSG
DGDHQVKWNARDGVNLGVDTLTTVQGPPWNLCPLPPVDQRNSGAAKEPLIGDMIEFYE
GHIYHYAMYIGQGKTIGVHSPRAAFSIPRITIHPIAAWWRVCYVPTQEQRLSYDQLKE
LENEPWPYAAVTNNCYDFCCRIMDLQDTWLERRLVTSGRFNHPTQDWSKDTPDFQQDS
KLEVVRDAVLAAINGLVSRPFKNLLNKLKPLNILNLLSNCDWTFMGIVETIILLMELF
GVFWDPPDVSNFIASLLPDMHLQGPEDLAKDLIPLILGGIGLAIGFTKDKVTKVMKSA
VDGLRAATQLGQYGLEIFAVIKKYFFGGDQTEKTLKDIETAVIDMEVISTTAITQLVR
DKQSARTYMAILDAEEEKARKLSVKHADPHVVSTTNALISRISMARSALAKAQAELTN
RVKPVVIMMCGPPGIGKTKAAEYLAKRLANEIRPGGKVGLVPREAVDHWDGYHGEEVM
LWDDYGMSKIADDCNKLQAIADTAPLTLNCDRIEKKGMQFVSDAIVITTNAPGPAPVD
FVNLGPVCRRVDFLVYCSAPEVEQVRRVSPGDTSALKDCFKDDFSHLKMEIAPQGGFD
NQGNTPFGKGVMRPTTINRLLIQAVALTMERQDEFQMQGPTYDFDSDRISAFTSLAKA
NGLSLIGMASLGKRLRSVNSVHGLKNALAGYTITPCTIKWQARFYDIESDGNVVKICE
NTSAQTQRQQSIDTAVLALTRLRAARAAAYASCLQCAITTVLQMAGSALVIHRAVKRM
FGTHTNAVSLEGPDREHRCRVHQAKANGHGPIGHDDVIEKYGLCETEDECTQEQETTM
ELPTASHEGKNKGKTKKGRGRRANYNAFSRRGLSDEEYEEYKKVREEKGGNYSIQEYL
EDRQRYEEEMAEVQAGGDGGIGETEMEIRHRVFFKSKTKKNRQEERRQLGLVTGSEIR
KRKPIDWTPPKNEWADDDREVDYNEKISFEAPPTMWSRVTRFGSGWGFWVSPTVFITT
THVIPTGAKEFFGEPLDSIAIHRAGEFTQFRFSRKIRPDLTGMVLEEGCPEGVVCSIL
IKRDSGELLPLAVRMGAIASMKIQGRLVHGQSGMLLTGANAKGMDLGTLPGDCGAPYV
YKRNNDWVVCGVHAAATKSGNTVVCAVQAGEGETTLEGGDKGHYAGHEIVRNSKGPAL
SSKTKFWRSTPEPLPPGVYEPAYLGGKDPRVKGGPSLHQVLRDQLKPFAEPRGRMPEP
GLLEAAVETVTSMLEQVMDTPTPWSYADACQSLDKTTSSGYPYHKRKNDDWNGTTFIG
ELGEQAAHANNMYEQGKPMKPIYTAALKDELVKPEKIYQKIKKRLLWGADLSTVIRSA
RAFGPFCDAIKSHVIKLPIKVGMNSIEDGPLIYAEHAKYKNHFDADYSAWDSTQNRQI
MMESFSIMCRLTATPDLAAVVARDLLAPSEMDVGDFVIRVKEGLPSGFPCTSQVNSIN
HWLITLCALSEVTGLAPDVIQSQSYFSFYGDDEIVSTDIDFDPARLTQVLKEYGLRPT
RPDKSEGPIILRKSVDGLVFLRRTISKDAAGYQGRLDRNSIERQLWWTRGPNHDDPNE
TLIPHPQRKVQLISLLGEASLHGEKFYRKISGRVIQEIKTGGLEMYVPGWQAMFRWMR
FHDLGLWTGDRDLLPEFVNDDGV"
mat_peptide <1..1072
/gene="ORF1"
/product="p48"
mat_peptide 1073..2161
/gene="ORF1"
/product="NTPase"
mat_peptide 2162..2767
/gene="ORF1"
/product="p22"
mat_peptide 2768..3181
/gene="ORF1"
/product="VPg"
mat_peptide 3182..3724
/gene="ORF1"
/product="Pro"
mat_peptide 3725..5248
/gene="ORF1"
/product="RdRp"
gene 5235..6857
/gene="ORF2"
CDS 5235..6857
/gene="ORF2"
/note="major capsid protein"
/codon_start=1
/product="VP1"
/protein_id="QPJ58852.1"
/translation="MMMASKDAPTSPDGASGAGQLVPEVNTADQISMDPVAGASTAVA
TAGQVNMIDPWIFNNFVQAPQGEFTISPNNTPGDILFDLQLGPHLNPFLAHLSQMYNG
WVGNMRVRILLAGNAFTAGKIIICCVPPGFDARILTIAQATLFPHLIADVRTLEPVEL
PLEDVRNVLYHNSSQPQPTMRLVAMLYTPLRTGGGSGGTDAFVVAGRVLTCPAPDFSF
LFLVPPSVEQKTRVFSVPNIPLKDLSNSRVPTLIQGMFVSPDVNQSVQFQNGRCQIDG
QLQGTTPVSLSQLCKIRGKTSSNTRVLNLSEVDGTPFVPLESPAPVGFPDIGGCDWHV
GFTFEARDQDPSQNVTFATNDSSFVPYLGSISPHNGDGFHSGDIIGSLDWISAPSDGS
ALDVWSIPKYGSSLPDVTHLAPAVFPPGFGEVILYFHSKFPGSGPADKLRVPCLMPQE
FITHFCNEQAPIAGEAALLHYVDPDTGRNLGEFKLYPDGFMTCVPNSISSGPQTLPIN
GVFVFVSWVSRFYQLKPVGTASMARRLGLRRI"
gene 6857..>7456
/gene="ORF3"
CDS 6857..>7456
/gene="ORF3"
/note="minor structural protein; small basic protein"
/codon_start=1
/product="VP2"
/protein_id="QPJ58853.1"
/translation="MAQAIIGAIAASAAGSILGAGIQAGAEAGLQAQRYQQDLQLQQN
TFQHDREMIGYQVQASNALLAKNLNTRYTLLQAGGLSSADAARAVAGAPVTRIVDWNG
TRVAAPTSSATTLKSGGFMPVPIPLAQKSKQPLMAGQDNPNYAASSISRTASWVQSQN
SLRSMPPFHNDALRTVWVTPPGSSSTSSVQSSYYGVFNTD"
ORIGIN
1 taataccaaa cccattaaaa ttgaaaacac acagatggct cttgggcttc tgagccggga
61 gccatcacca tcgcccaacc gtggcccccc taaacaacaa cgggacaggg caccacggaa
121 tgtggctgaa acccaacagg cgatgggatg gacagaccca cctgttgacc aaaacctgcc
181 aacatgggaa gagctgagcc agtctgagaa gcagaagatc atagctgaga attcaaagtg
241 gtttgatgct ggtggtctag gcccggctac cctgccatcg aattactgtc gagtacagga
301 cagtggtgat ggtgaccatc aggttaaatg gaatgctaga gatggtgtca acctgggagt
361 tgacacctta acaactgtcc aaggcccccc gtggaattta tgcccacttc ccccagtcga
421 ccaacgtaat agcggggcag ctaaagagcc cctgattgga gacatgattg agttctatga
481 agggcacata taccattatg ccatgtacat aggtcaggga aaaacaattg gtgtgcattc
541 tcctagggct gctttttcca tacctaggat caccatacac ccaatcgctg cttggtggag
601 ggtgtgctat gtccccaccc aggaacaaag gctaagttat gaccaactca aggaacttga
661 aaatgaacct tggccatatg cagctgtcac caacaactgc tacgattttt gctgcaggat
721 aatggatcta caggatacat ggctggagag gagattggtg acatcaggcc gctttaatca
781 cccaactcag gactggtcca aggacacccc agatttccaa caagacagta agctagaggt
841 tgtccgtgat gccgtcttag cagccattaa tggcctggtc tcacgcccgt tcaagaactt
901 gctaaataag ctcaaaccac taaacattct caacctatta tccaactgtg attggacctt
961 catgggtata gttgaaacca taatattgct gatggagctc tttggtgtct tttgggaccc
1021 ccctgacgtg tccaacttca tagcttccct ccttcctgac atgcaccttc aaggcccaga
1081 agatctggct aaagatctga taccactcat actgggtgga attgggttgg ccataggctt
1141 cactaaggac aaagtgacaa aggtgatgaa aagtgcagtt gatggtttgc gtgcggccac
1201 tcagctaggg caatatggct tggagatctt cgcagtcatc aagaaatact tctttggagg
1261 tgatcagacg gagaagacac ttaaggacat tgagacagca gtcattgaca tggaggttat
1321 ctccacgaca gctataacgc aactagttag agacaaacag tctgccagga cttatatggc
1381 tatactagat gctgaagagg aaaaggcccg aaaactgtct gtgaaacatg ctgaccccca
1441 cgtggtgtca accaccaacg cactaatttc gcgcatctca atggcgcgtt ctgccctagc
1501 taaagcacaa gctgagttga caaacagagt taagccagta gtgataatga tgtgtggccc
1561 tcctggtata ggcaagacga aggctgctga gtacctggcc aaacggcttg ccaatgaaat
1621 acgtccaggt ggaaaagttg gcctagtccc acgtgaagct gtcgaccact gggacggtta
1681 tcatggtgag gaggtcatgt tgtgggatga ctatgggatg tcaaagatag cagatgattg
1741 caataagcta caagcaattg ctgacacagc cccattaaca ctcaactgtg accggataga
1801 aaagaagggt atgcagtttg tgtcagatgc tattgttata actaccaacg ctcccgggcc
1861 agcccctgtt gactttgtca acttaggtcc tgtctgtcgg cgtgttgact tcctagtcta
1921 ttgttctgcc ccagaagtcg aacaggtacg tcgtgttagc cccggagaca ctagcgcact
1981 caaagattgc ttcaaggatg acttctctca ccttaagatg gaaattgcac cacagggtgg
2041 atttgataac caagggaaca cgccatttgg caagggcgtc atgcgcccca ccactataaa
2101 caggctttta atccaggcgg ttgctctcac catggaacgc caagatgaat ttcagatgca
2161 aggaccaacc tacgattttg actcagacag gatttcagct ttcactagcc tggccaaagc
2221 caatggttta agcttgattg gtatggcaag tctcggaaag agactacgca gtgtcaactc
2281 agtccatggc ctcaaaaatg ccctagccgg ttacaccatt acaccatgca ccataaaatg
2341 gcaagccagg ttctatgata tagaatctga cggtaatgtg gtcaagatct gtgagaacac
2401 aagtgcacaa acccagcgcc aacagtccat tgataccgct gtccttgcgc tcacccgact
2461 cagggctgca agggctgctg cgtacgcatc ttgcctacaa tgtgctatca cgactgtatt
2521 gcagatggca ggttcagccc ttgttataca ccgagccgtc aagcgcatgt ttggcactca
2581 caccaatgcc gtctccttgg aaggtcctga cagggaacat cgctgtcgag tgcaccaagc
2641 caaggctaac ggccacggcc ccattggaca tgatgatgtt atagaaaaat atgggttgtg
2701 tgaaacagaa gatgagtgca cccaggagca agaaaccacc atggaattac ccactgcaag
2761 ccatgaaggt aagaacaagg ggaagaccaa gaagggccga ggccgaagag ctaattacaa
2821 cgccttctct agacgtggtc taagtgatga ggaatacgag gagtacaaga aggttagaga
2881 agagaaaggt ggaaactaca gcatccaaga ataccttgaa gataggcaac gctatgagga
2941 ggagatggct gaggtacagg ccggcggcga tggtggaata ggtgagacgg agatggaaat
3001 acgccatcgg gtcttcttta agtctaaaac gaagaagaac cgccaggaag aacgccgaca
3061 gcttggcttg gtcacgggca gtgagataag aaagagaaaa cccatagatt ggaccccccc
3121 caaaaatgaa tgggcagatg acgacagaga agtggattac aatgagaaaa taagttttga
3181 agcccctccc accatgtgga gccgagttac ccgattcggt tccggatggg ggttttgggt
3241 tagccccacg gtgttcatca ccaccaccca cgtcatacca actggggcca aagaattctt
3301 tggagaacca ttagattcca ttgccataca tcgtgcagga gagttcacac agttccgctt
3361 ctcaagaaag atacggccag atttgacagg gatggttctt gaggaaggat gtcctgaagg
3421 agtggtttgc tcaatcttga tcaagcgtga ctcaggtgag ctgttaccgt tggctgtgcg
3481 catgggggct atagcttcaa tgaaaataca gggtcggttg gtccatggtc aatctggcat
3541 gctcctaact ggtgccaatg caaaaggtat ggacctgggt accctcccag gtgattgtgg
3601 ggcaccctat gtctacaaga gaaacaatga ttgggtggtc tgcggtgtcc acgcagcagc
3661 caccaagtct ggtaacactg tggtttgtgc agtacaagca ggtgaggggg agaccactct
3721 agaagggggt gataagggac actatgccgg gcatgaaata gttaggaata gtaagggccc
3781 cgcgctctca tctaaaacta agttctggag atcaacacca gaaccccttc ctccaggtgt
3841 ctatgaacca gcttacctag ggggcaaaga tcctagggtt aagggtggcc cttctttaca
3901 ccaggtcctt cgggaccaac tgaaaccctt tgctgagcca cgtgggcgca tgccagagcc
3961 aggtttgttg gaggctgctg ttgagacagt gacttctatg ctggaacagg ttatggatac
4021 gcctacacca tggtcatatg cagatgcctg ccagtcatta gacaagacca ccagttctgg
4081 atacccatac cacaagagga agaatgatga ttggaacggc accaccttca taggggagct
4141 tggtgagcag gcagcccacg caaacaacat gtatgagcaa ggtaagccca tgaagcccat
4201 atatactgca gccctcaaag atgaacttgt taagccagag aagatctatc aaaagattaa
4261 gaaaagatta ctgtgggggg ctgacctgtc aaccgtcata cggtctgcgc gggcttttgg
4321 ccccttctgt gacgcaataa agtcccatgt gatcaagttg cccattaagg ttggtatgaa
4381 ttcaattgag gatggccctc taatctatgc tgagcatgca aaatataaaa atcactttga
4441 tgcagattat tcagcctggg actcaacaca aaatagacaa attatgatgg agtctttctc
4501 aatcatgtgt cgcctcactg ccacaccaga tttggcggct gttgtggcta gagacctgct
4561 agccccttct gaaatggacg tgggggactt tgtaattaga gttaaggagg gtctcccatc
4621 aggcttcccc tgcacttcac aagtcaatag tataaaccac tggctcatca cattgtgtgc
4681 cctgtctgag gtcacgggcc tggcacccga tgttatacaa tcacagtcat atttctcttt
4741 ctatggggac gatgaaatcg tgtccacaga cattgacttt gacccggctc ggctcaccca
4801 ggtccttaag gagtatgggc tgcgtccaac tcgcccagac aaaagtgagg gtcccataat
4861 cttgaggaaa agtgtagatg gcttagtgtt ccttaggcgc accatctcca aagatgcagc
4921 tggttaccaa ggccggttgg ataggaactc tatagaaaga caactgtggt ggacccgtgg
4981 ccccaatcat gatgatccaa atgagacgct catccctcat ccccaaagaa aggtccagct
5041 tatatcactg ttgggagagg catcacttca tggggaaaag ttttacagaa agatttcagg
5101 cagagttatc caagagatta aaactggtgg attggaaatg tacgtgccag gctggcaggc
5161 catgttccgc tggatgcgtt ttcatgacct tggactttgg acaggagatc gcgatctcct
5221 gcccgaattc gtaaatgatg atggcgtcta aggacgcccc aacatcgcct gatggcgcca
5281 gtggcgctgg ccagctagtg ccggaggtta atacagctga ccaaatttca atggaccctg
5341 ttgcaggtgc ttccactgca gttgcaacag ctgggcaagt taatatgatt gatccatgga
5401 tattcaataa ttttgtccag gccccccagg gtgaatttac tatttcccca aataataccc
5461 ccggtgacat tttgtttgat ttacaattag gcccccattt gaatcccttc ttagctcatt
5521 tatcacagat gtataatgga tgggttggca acatgcgggt tcgcatattg ctggcaggca
5581 atgctttcac agctggtaag ataatcatat gttgtgttcc ccccggcttt gatgctagaa
5641 tacttactat tgctcaagct actctattcc ctcacttgat tgctgatgtt agaactcttg
5701 aaccagtaga attacctctc gaggatgtgc gcaacgtcct ctaccacaac agcagccagc
5761 cacaaccaac catgcggctg gtagctatgc tatacacccc actgcgtaca ggcggtgggt
5821 ctggaggcac tgatgctttt gtggttgctg ggagagtgct gacatgtcct gcaccagatt
5881 ttagttttct gtttcttgtt cctccctctg tagagcaaaa gactagggtt ttcagtgtac
5941 ccaatatacc actcaaggat ctctcaaact ccagagtgcc aaccttgatt caaggcatgt
6001 ttgtttctcc tgatgttaat caatcagtgc aattccaaaa tgggcggtgc caaattgatg
6061 gccagctgca aggcaccacc ccagtgtccc tcagccaatt atgtaagatc agaggtaaga
6121 cttccagtaa taccagagta cttaatctta gtgaggttga tgggacacct tttgtgcccc
6181 ttgagtcccc tgcacctgta ggtttcccag atataggcgg gtgtgattgg catgtcggct
6241 tcacttttga ggcacgagac caggacccct cccagaatgt gacctttgca actaatgatt
6301 ctagctttgt gccatatctt ggcagtattt caccccataa tggtgatggg ttccatagtg
6361 gtgatattat aggtagttta gattggatct cagctccatc ggatggttct gcacttgatg
6421 tgtggtccat accaaaatat ggatcatctc tcccagatgt tacccatcta gctcctgcag
6481 tctttccccc tggctttggt gaggttatcc tctacttcca ttctaaattt cctggttctg
6541 gtcctgctga taaacttagg gtcccatgtc tgatgccaca agagttcata acacactttt
6601 gtaatgagca agcacccata gcgggggagg ctgccctcct tcactatgtg gatcctgaca
6661 caggcaggaa cttaggggag tttaagcttt atccagatgg ctttatgaca tgtgtgccca
6721 acagcatcag cagtggcccc cagactctgc caatcaatgg tgtgtttgta tttgtgtcct
6781 gggtatccag attttaccaa cttaagcctg tgggaacggc ctcaatggcc aggaggcttg
6841 gtcttcggcg catataatgg ctcaagccat cataggtgcc atagcagctt ctgctgctgg
6901 aagtatactc ggtgctggca tacaagctgg tgctgaagct ggactccaag cccaacggta
6961 tcaacaggat cttcaattac aacagaatac cttccaacat gatagggaaa tgatagggta
7021 ccaggtccaa gccagcaatg ccctgttggc caagaatctc aacactaggt atactctact
7081 gcaggcaggg ggtttatcta gtgcggatgc agccagggct gttgcgggtg cccctgtcac
7141 tcgcatagtg gactggaacg ggacccgtgt ggcagccccc acatcgagcg ccactacatt
7201 aaaatctggt ggatttatgc ctgtccctat acccctagcc caaaaatcca aacaacctct
7261 gatggctggg caagataacc ctaattatgc tgcttcctct atttctagaa ctgcctcatg
7321 ggtgcaatcc cagaactctt taaggtccat gccccctttt cacaatgatg ctctccggac
7381 tgtgtgggtc acgccacctg gttcttcttc tacatcttct gtgcagtcta gttactatgg
7441 tgtctttaat acagac
//