Typing tool
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Typing tool
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Complete norovirus genomes
| MW305502 | GI.6 | |
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| GI.P6 |
ORF1: 1..5332
ORF2: 5316..6938
ORF3: 6938..7567
LOCUS MW305502 7569 bp RNA linear VRL 13-APR-2022
DEFINITION Norovirus GI isolate 11652 nonstructural polyprotein (ORF1) gene,
partial cds; and VP1 (ORF2) and VP2 (ORF3) genes, complete cds.
ACCESSION MW305502
VERSION MW305502.1
KEYWORDS .
SOURCE Norovirus GI
ORGANISM Norovirus GI
Viruses; Riboviria; Orthornavirae; Pisuviricota; Pisoniviricetes;
Picornavirales; Caliciviridae; Norovirus; Norwalk virus.
REFERENCE 1 (bases 1 to 7569)
AUTHORS Tohma,K., Lepore,C.J., Martinez,M., Degiuseppe,J.I., Khamrin,P.,
Saito,M., Mayta,H., Nwaba,A.U.A., Ford-Siltz,L.A., Green,K.Y.,
Galeano,M.E., Zimic,M., Stupka,J.A., Gilman,R.H., Maneekarn,N.,
Ushijima,H. and Parra,G.I.
TITLE Genome-wide analyses of human noroviruses provide insights on
evolutionary dynamics and evidence of coexisting viral populations
evolving under recombination constraints
JOURNAL PLoS Pathog 17 (7), e1009744 (2021)
PUBMED 34255807
REMARK Publication Status: Online-Only
REFERENCE 2 (bases 1 to 7569)
AUTHORS Tohma,K., Lepore,C.J., Martinez,M., Degiuseppe,J.I., Khamrin,P.,
Saito,M., Mayta,H., Nwaba,A., Ford-Siltz,L.A., Galeano,M.E.,
Zimic,M., Stupka,J.A., Gilman,R.H., Maneekarn,N., Ushijima,H.,
Green,K.Y. and Parra,G.I.
TITLE Direct Submission
JOURNAL Submitted (23-NOV-2020) CBER/OVRR/DVP/LHV, U.S. Food and Drug
Administration, 10903 New Hampshire Avenue, Silver Spring, MD
20993, USA
COMMENT ##Assembly-Data-START##
Assembly Method :: High-performance Integrated Virtual
Environment (HIVE) v. 2
Sequencing Technology :: Illumina
##Assembly-Data-END##
FEATURES Location/Qualifiers
source 1..7569
/organism="Norovirus GI"
/mol_type="genomic RNA"
/isolate="11652"
/isolation_source="feces"
/host="Homo sapiens"
/db_xref="taxon:122928"
/country="Japan"
/collection_date="12-Jun-2013"
/note="genotype: GI.6[GI.P6]"
gene <1..5332
/gene="ORF1"
CDS <1..5332
/gene="ORF1"
/codon_start=2
/product="nonstructural polyprotein"
/protein_id="QPJ58842.1"
/translation="TAASASSTGDNSNTMKDRFLAKLKSLGNTKPIKIENTQMALGLL
SREPSPSPSRDPPKQQRDRAPRNVAETQQAMGWTDPPVDQNLPTWEELSQSEKQKIMA
ENSRWFDAGGLGPATLPSNYCRVQDSGDGDHQVKWSAKGGVNLGVDTLTTVQGPPWNL
CPLPPADQRNSGAAKEPLIGDMIEFYEGHIYHYAMYIGQGKTIGVHSPRAAFSIPRIT
IHPIAAWWRVCYVPTQEQRLSYDQLKELENEPWPYAAVTNNCYEFCCRIMDLQDTWLE
RRLVTSGRFNHPTQDWSKDTPDFQQDSKLEVVRDAVLAAINGLVSRPFKNLLNKLKPL
NILSLLSNCDWTFMGIVETIILLMELFGVFWDPPDVSNFIASLLPDMHLQGPEDLAKD
LIPLILGGIGLAIGFTKDKVTKVMKSAVDGLRAATQLGQYGLEVFAVIKKYFFGGDQT
EKTLKDIETAVIDMEVISTTAITQLVRDKQSARTYMAILDAEEEKARKLSVKHADPHV
VSTTNALISRISMARSALAKAQAELTNRVKPVVIMMCGPPGIGKTKAAEYLAKRLANE
IRPGGKVGLVPREAVDHWDGYHGEEVMLWDDYGMSKIADDCNKLQAIADTAPLTLNCD
RIEKKGMQFVSDAIVITTNAPGPAPVDFVNLGPVCRRVDFLVYCSAPEVEQVRRVSPG
DTGALKDCFKDDFSHLKMEIAPQGGFDNQGNTPFGKGVMRPTTINRLLIQAVALTMER
QDEFQMQGPTYDFDSDRISAFTSLAKANGLSLIGMASLGKRLRSVNSVHGLKNALAGY
TITPCTIKWQARFYDIESDGSVVKICENTTAQTQRQQSIDTAVLALTRLRAARAAAYA
SCLQSAITTVLQMAGSALVIHRAVKRMFGTHTNAVSLEGPDKEHRCRVHQAKANGRGP
IGHDDVIEKYGLCETEDESTQEQEATMELPTASHEGKNKGKTKKGRGRRANYNAFSRR
GLSDEEYEEYKKVREEKGGNYSIQEYLEDRQRYEEEMAEVQAGGDGGIGETEMEIRHR
VFFKSKTKKNRQEERRQLGLVTGSEIRKRKPIDWTPPKNEWADDDREVDYNEKISFEA
PPTMWSRVTRFGSGWGFWVSPTVFITTTHVIPTGAKEFFGEPLDSIAIHRAGEFTQFR
FSRKIRPDLTGMVLEEGCPEGVVCSILIKRDSGELLPLAVRMGAIASMKIQGRLVHGQ
SGMLLTGANAKGMDLGTLPGDCGAPYVYKRNNDWVVCGVHAAATKSGNTVVCAVQAGE
GETTLEGGDKGHYAGHEIVRNSKGPALSSKTKFWRSTPEPLPPGVYEPAYLGGKDPRV
KGGPSLHQVLRDQLKPFAEPRGRMPEPGLLEAAVETVTSMLEQVMDTPTPWSYADACQ
SLDKTTSSGHPYHKRKNDDWNGTTFVGELGEQAAHANNMYEQGKSMKPLYTAALKDEL
VKPEKVYQKIKKRLLWGADLSTVIRSARAFGPFCDAIKSHVIKLPIKVGMNSIEDGPL
IYAEHAKYKNHFDADYSAWDSTQNRQIMMESFSIMCRLTASPDLAAVVARDLLAPSEM
DVGDFVIRVKEGLPSGFPCTSQVNSINHWLITLCALSEVTGLAPDVIQSQSYFSFYGD
DEIVSTDIDFDPVRLTQVLREYGLRPTRPDKSEGPIILRRSVDGLVFLRRTISKDAAG
YQGRLDRNSIERQLWWTRGPNHDDPNETLIPHPQRKVQLISLLGEASLHGEKFYRKIS
GRVIQEIKTGGLEMYVPGWQAMFRWMRFHDLGLWTGDRDLLPEFVNDDGV"
mat_peptide <1..1153
/gene="ORF1"
/product="p48"
mat_peptide 1154..2242
/gene="ORF1"
/product="NTPase"
mat_peptide 2243..2848
/gene="ORF1"
/product="p22"
mat_peptide 2849..3262
/gene="ORF1"
/product="VPg"
mat_peptide 3263..3805
/gene="ORF1"
/product="Pro"
mat_peptide 3806..5329
/gene="ORF1"
/product="RdRp"
gene 5316..6938
/gene="ORF2"
CDS 5316..6938
/gene="ORF2"
/note="major capsid protein"
/codon_start=1
/product="VP1"
/protein_id="QPJ58843.1"
/translation="MMMASKDAPTSPDGASGAGQLVPEVNTADQISMDPVAGASTAVA
TAGQVNMIDPWIFNNFVQAPQGEFTISPNNTPGDILFDLQLGPHLNPFLAHLSQMYNG
WVGNMRVRILLAGNAFTAGKIIICCVPPGFDARILTIAQATLFPHMIADVRTLEPVEL
PLEDVRNVLYHNSSQPQPTMRLVAMLYTPLRTGGGSGGTDAFVVAGRVLTCPAPDFSF
LFLVPPSVEQKTRVFSVPNIPLKDLSNSRVPTLIQGMFVSPDVNQSVQFQNGRCQIDG
QLQGTTPVSLSQLCKIRGKTSSNARVLNLSEVDGTPFVPLESPAPVGFPDLGGCDWHV
GFTFEARDQDPSQNVTFATNDSSFVPYLGSISPHNGDGFHSGDIIGSLDWISAPSDGS
TLDVWSIPKYGSSLPDVTHLAPAVFPPGFGEVILYFHSKFPGSGPTDKLRVPCLIPQE
FITHFCNEQAPIAGEAALLHYVDPDTGRNLGEFKLYPDGFMTCVPNSISSGPQTLPTN
GVFVFVSWVSRFYQLKPVGTASMARRLGLRRI"
gene 6938..7567
/gene="ORF3"
CDS 6938..7567
/gene="ORF3"
/note="minor structural protein; small basic protein"
/codon_start=1
/product="VP2"
/protein_id="QPJ58844.1"
/translation="MAQAIIGAIAASAAGSILGAGIQAGAEAGLQAQRYQQDLQLQQN
TFQHDREMIGYQVQASNALLAKNLNTRYTLLQAGGLSSADAARAVAGAPVTRIVDWNG
TRVAAPTSSATTLKSGGFMPVPIPLTQKSKQPIMTGQDNPNYAASSISRTASWVQSQN
SLRSMPPFHNDALRTVWVTPPGSSSTSSVQSSYYGVFNTDRLPLFANRR"
ORIGIN
1 tactgctgcc agcgcttcaa gcactggtga caatagtaac acaatgaagg atcgcttttt
61 agcgaaactc aagagtttgg gcaacaccaa acccataaaa attgaaaaca cacagatggc
121 tcttgggctt ctgagccggg agccgtcgcc atcgcccagc cgtgaccccc ctaaacaaca
181 acgggacagg gcaccacgga atgtggctga aacccaacag gcaatgggat ggacagaccc
241 acctgttgac caaaatctgc caacatggga ggagctcagc cagtctgaga aacagaagat
301 catggctgag aattcaaggt ggtttgatgc tggtggccta ggtccagcta ccctaccatc
361 gaattactgt cgtgtacaag acagtggcga tggtgaccat caggttaaat ggagtgctaa
421 aggtggtgtc aacctgggag ttgacacctt aacaaccgtc cagggccccc catggaactt
481 gtgcccactt cccccagccg atcaacgcaa tagcggggca gctaaagagc ccctgattgg
541 agacatgatt gagttttatg aagggcacat atatcattat gccatgtaca taggccaggg
601 aaaaacgatt ggtgtgcact cccctagggc cgctttttcc atacctagga ttaccataca
661 cccaatcgct gcttggtgga gggtgtgcta tgtccccacc caagagcaga ggctaagtta
721 tgatcaactc aaggaacttg aaaatgaacc ttggccatat gcagctgtca ccaacaactg
781 ctacgagttt tgctgcagga taatggatct gcaggatact tggttggaga ggagattggt
841 gacatcaggc cgctttaacc acccaactca ggactggtcc aaggacaccc cagatttcca
901 acaagacagc aagctagagg ttgttcgtga tgccgttcta gcagctatta atggcctggt
961 ctcacgcccg ttcaagaatt tgctaaataa gctcaaacca ttaaacatcc tcagcctcct
1021 atccaattgt gattggacct tcatgggcat agttgaaacc ataatattgc taatggagct
1081 ctttggggtc ttttgggatc cccctgatgt gtccaacttc atagcttccc tccttcctga
1141 catgcacctt caaggcccag aagatctggc taaggatctg ataccactta tattgggtgg
1201 aatcgggttg gccataggct tcactaagga caaagtgaca aaggtgatga agagtgcagt
1261 tgatggtttg cgtgcggcca ctcaactagg gcaatatggc ttggaagtct tcgcggtcat
1321 caagaaatac ttctttgggg gtgatcaaac agagaagaca cttaaagaca ttgagacagc
1381 agtcattgac atggaggtca tctccacgac agccataaca caattggtca gggacaaaca
1441 atccgccagg acctatatgg ccatactaga tgctgaagag gaaaaggccc ggaaactgtc
1501 tgtgaaacat gctgaccccc acgtggtgtc aaccaccaac gcactgattt cgcgcatctc
1561 aatggcgcgt tctgccctgg ctaaagcgca agctgagctg acaaacagag ttaagccagt
1621 ggtgataatg atgtgtggcc ctcctggtat aggcaagacg aaggctgccg agtacctagc
1681 caaacggctt gccaatgaaa tacgtccagg tgggaaagtt ggtctggtcc cacgtgaagc
1741 tgtcgaccac tgggacggtt accatggtga ggaggttatg ttgtgggatg actatgggat
1801 gtcaaagata gcagatgact gcaataaact gcaagcaatt gctgacacag ccccattaac
1861 actcaattgt gaccggatag aaaagaaagg tatgcagttt gtgtcagatg ctattgtcat
1921 aaccaccaat gccccagggc cagcccctgt tgactttgtc aatttaggac ctgtctgtcg
1981 gcgtgttgac ttcctggtct attgttctgc cccagaagtc gaacaggtgc gtcgtgttag
2041 ccccggagac actggcgcac tcaaagattg cttcaaggat gacttctcac accttaaaat
2101 ggaaattgca ccacagggtg gatttgacaa tcaagggaac acaccatttg gcaagggcgt
2161 catgcgcccc accaccataa acagactttt gattcaggcg gttgctctca ccatggaacg
2221 ccaggatgag tttcagatgc aaggaccaac ctacgatttt gactcagaca ggatttcagc
2281 tttcactagt ctagccaaag ccaatggttt aagcttgatt ggtatggcaa gtctcgggaa
2341 gagactacgc agtgtcaact cagtccatgg cctcaaaaat gccctagccg gttacactat
2401 cacaccatgt accataaaat ggcaagccag gttttatgat atagaatctg atggtagtgt
2461 ggtcaagata tgtgagaaca caactgcaca aacccagcgc caacagtcca ttgataccgc
2521 tgtcctcgcg ctcacccgac tcagggctgc aagggccgct gcgtatgcat cctgtctgca
2581 gagtgctatc acaactgtgt tgcagatggc aggttcagcc cttgtcatac atcgagccgt
2641 caagcgcatg ttcggcaccc acaccaatgc cgtctcccta gagggtcctg acaaggaaca
2701 tcgctgtcga gtgcatcagg ctaaggctaa tggtcgcggc cccattggac atgatgatgt
2761 tatagagaaa tatgggttgt gtgaaacaga agatgagtcc acccaggagc aggaagccac
2821 catggaactg cccactgcaa gccatgaagg caagaacaag gggaaaacca agaagggccg
2881 aggccgaaga gccaactaca acgccttctc tagacgtggc ctaagtgatg aggagtacga
2941 ggagtacaag aaggttagag aagagaaagg tggaaactac agcatccaag agtacctcga
3001 agacaggcaa cgctatgagg aggagatggc tgaggtgcag gccggcggcg atggtggaat
3061 aggtgagacg gagatggaaa tacgtcatcg ggtcttcttt aagtccaaaa caaagaagaa
3121 tcgccaggag gaacgccggc agcttggctt agtcacgggc agtgagataa gaaagagaaa
3181 gcccatagat tggacccccc ccaaaaatga atgggcagac gatgacagag aagtggatta
3241 caatgagaaa ataagttttg aagcccctcc caccatgtgg agccgagtta cacgattcgg
3301 ttccgggtgg gggttttggg ttagtcccac ggtgttcatc accaccaccc atgttatacc
3361 aactggggcc aaagaattct ttggggaacc attagattcc attgccatac accgtgcagg
3421 agagttcaca caattccgct tctcaagaaa gatacggcca gatctaacag ggatggttct
3481 tgaggaaggg tgtcctgaag gagtggtttg ctcaatcctg atcaagcgtg actcaggtga
3541 gctgctaccg ttggctgtgc gcatgggggc tatagcttca atgaaaatac agggccggtt
3601 ggtccatggt cagtctggta tgctcctaac tggtgccaat gcaaaaggta tggacctggg
3661 tactctccca ggtgattgtg gggcgcccta tgtctacaag agaaacaatg attgggtggt
3721 ctgcggtgtc cacgcagcag ccaccaagtc tggtaacact gtggtctgtg cagtacaagc
3781 aggtgagggg gagaccactc tagaaggagg tgataaggga cattatgctg ggcatgaaat
3841 agtcaggaat agcaagggcc ccgcactctc atctaaaact aagttctgga gatcaacacc
3901 agagcccctg cccccaggtg tctatgaacc agcttatcta ggaggcaaag atcctagagt
3961 caagggtggt ccttctttgc accaggtcct tcgggatcaa ctgaaacctt ttgcagaacc
4021 acgtgggcgc atgccagagc caggtttgct ggaggctgct gttgagacag tgacttctat
4081 gctggaacag gttatggata cgcccacacc atggtcatac gcagatgctt gccagtcatt
4141 agacaagacc accagttctg gacaccccta ccacaagagg aagaatgatg attggaacgg
4201 caccaccttc gtgggggagc ttggtgagca ggcagcccat gcaaacaaca tgtatgagca
4261 aggcaagtcc atgaaacccc tatacacagc agccctcaaa gatgaacttg tcaaaccaga
4321 gaaggtctat caaaagatca agaaaaggtt gctgtgggga gctgacctgt cgaccgttat
4381 acggtccgcg cgggcttttg gccccttctg tgatgcaata aaatcccatg tgatcaaatt
4441 gcccattaag gttggtatga actcaattga ggatggccct ctaatctatg ctgaacatgc
4501 aaaatataag aatcactttg atgcagatta ttcagcctgg gactcaacac aaaatagaca
4561 aatcatgatg gagtccttct caatcatgtg tcgcctcact gcctcaccag atttggcagc
4621 tgttgtggct agagacctgt tagctccttc tgagatggat gtgggagact ttgtaattag
4681 agttaaggag ggtctcccat caggcttccc ctgtacttca caagtcaata gtataaacca
4741 ttggctcatt acattgtgtg ctctgtctga ggtcacgggt ctggcacccg atgttattca
4801 gtcacagtca tatttctctt tctatgggga cgatgaaatc gtgtccacag acattgattt
4861 tgacccggtc cggctcaccc aggttcttag ggagtatggg ctgcgtccaa ctcgtccaga
4921 caaaagtgag ggccccataa ttttgaggag aagtgtagat ggcttggtgt tccttaggcg
4981 taccatctcc aaagacgcag ctggctacca aggccggttg gataggaatt ccatagaaag
5041 acaactgtgg tggacccgtg gccccaatca tgatgatcca aatgagacac ttatccctca
5101 cccccaaaga aaggtccagc ttatatcact gttaggagag gcatcacttc atggggaaaa
5161 gttttacaga aagatttcag gtagagtcat ccaagagatc aaaacaggtg gattggaaat
5221 gtatgtgcca ggctggcagg ccatgttccg ctggatgcgt tttcatgacc ttggactttg
5281 gacaggagat cgcgatctcc tgcccgaatt cgtaaatgat gatggcgtct aaggacgccc
5341 caacatcgcc tgatggcgcc agtggcgctg gccagctagt gccggaggtt aatacagctg
5401 accaaatttc aatggatcct gttgcgggtg cttccactgc agttgcaacc gctggacaag
5461 ttaatatgat tgatccatgg atattcaata attttgtcca ggcccctcag ggtgaattta
5521 ctatttcccc aaataatacc cccggtgata ttttgtttga tttacaattg ggcccccatt
5581 tgaatccctt cttagctcat ttatcacaga tgtataatgg gtgggtcggc aatatgcggg
5641 tccgcatatt gctggcaggc aatgctttta cagctggcaa gataatcata tgttgtgtcc
5701 cccccggttt tgatgctagg atacttacta ttgctcaagc tactctattt cctcatatga
5761 ttgctgatgt taggactctt gaaccggtag agttacctct cgaggacgtg cgtaatgtcc
5821 tctaccacaa cagcagccag ccacagccaa ccatgcgtct ggtggctatg ctatacaccc
5881 cactgcgcac aggcggtggg tctggaggca ctgatgcttt tgtggttgct gggagagtgc
5941 tgacatgtcc tgcaccagac ttcagttttc tattccttgt tcctccctct gtagagcaaa
6001 agactagggt cttcagtgtg cccaatatac cactcaagga tctctcaaac tctcgagtgc
6061 caaccttgat acaaggtatg tttgtttctc ctgatgttaa tcaatcagtg caattccaaa
6121 atgggcggtg ccaaattgat ggccagttac aaggtactac cccagtgtcc ctcagccaat
6181 tatgtaagat cagaggtaag acttccagca atgccagagt actcaacctt agtgaggttg
6241 atgggacacc ttttgtgccc cttgagtccc ctgcacctgt aggtttccca gatttaggcg
6301 ggtgtgattg gcatgtcggc tttacttttg aggcacgaga ccaggaccct tcccagaacg
6361 tgacctttgc aactaatgat tctagctttg tgccatatct tggcagtatc tcaccccata
6421 atggtgatgg gttccatagt ggtgatatta taggtagttt agattggatt tcagctccat
6481 cggatggttc cacacttgac gtgtggtcca taccaaaata tggatcatct ctcccagatg
6541 tcactcatct ggcccctgca gtttttcccc ctggttttgg tgaggtcatc ctctactttc
6601 actccaaatt tcctggttct ggccctactg ataaacttag ggtcccatgt ctgataccac
6661 aagagttcat aacacacttc tgcaatgagc aagcacccat agcgggggag gctgccctcc
6721 ttcactatgt ggaccctgac acaggtagga acttggggga attcaagctt tatccagatg
6781 gctttatgac atgtgtgcct aacagcatca gcagtggccc ccagactctg ccaactaatg
6841 gtgtgtttgt gtttgtgtcc tgggtgtcca gattttacca acttaagcct gtgggaacgg
6901 cctcaatggc caggaggctt ggtcttcggc gcatataatg gctcaagcca tcataggtgc
6961 catagcagct tctgctgctg gaagtatact cggtgctggc atacaagctg gtgctgaggc
7021 tggactccaa gcccaacggt atcaacagga tcttcaatta caacagaata ctttccagca
7081 tgatagggaa atgatagggt accaagtcca agccagcaat gccctattgg ccaagaatct
7141 caacactagg tatactctac tgcaggcagg gggtttatct agtgcggatg cagctagggc
7201 tgttgcgggt gctcctgtta ctcgcatagt ggactggaac gggacccgtg tggcagcccc
7261 cacatcgagc gctactacac taaaatctgg tgggtttatg cctgtcccta tacccttaac
7321 tcaaaagtct aaacaaccta taatgactgg gcaagataat cctaactatg ctgcttcctc
7381 tatttctaga actgcctcat gggtgcaatc ccagaattct ttgagatcta tgcccccctt
7441 tcataatgat gctctccgga ctgtgtgggt cacgccaccc ggttcttctt ctacatcttc
7501 tgtgcagtct agctattatg gtgtctttaa tacagataga ttacccctct tcgcaaatag
7561 gaggtaggg
//