Typing tool
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Typing tool
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Complete norovirus genomes
| MW305495 | GI.3 | |
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| GI.P3 |
ORF1: 1..5367
ORF2: 5351..6982
ORF3: 6982..7629
LOCUS MW305495 7704 bp RNA linear VRL 13-APR-2022
DEFINITION Norovirus GI isolate Arg4450 nonstructural polyprotein (ORF1) gene,
partial cds; and VP1 (ORF2) and VP2 (ORF3) genes, complete cds.
ACCESSION MW305495
VERSION MW305495.1
KEYWORDS .
SOURCE Norovirus GI
ORGANISM Norovirus GI
Viruses; Riboviria; Orthornavirae; Pisuviricota; Pisoniviricetes;
Picornavirales; Caliciviridae; Norovirus; Norwalk virus.
REFERENCE 1 (bases 1 to 7704)
AUTHORS Tohma,K., Lepore,C.J., Martinez,M., Degiuseppe,J.I., Khamrin,P.,
Saito,M., Mayta,H., Nwaba,A.U.A., Ford-Siltz,L.A., Green,K.Y.,
Galeano,M.E., Zimic,M., Stupka,J.A., Gilman,R.H., Maneekarn,N.,
Ushijima,H. and Parra,G.I.
TITLE Genome-wide analyses of human noroviruses provide insights on
evolutionary dynamics and evidence of coexisting viral populations
evolving under recombination constraints
JOURNAL PLoS Pathog 17 (7), e1009744 (2021)
PUBMED 34255807
REMARK Publication Status: Online-Only
REFERENCE 2 (bases 1 to 7704)
AUTHORS Tohma,K., Lepore,C.J., Martinez,M., Degiuseppe,J.I., Khamrin,P.,
Saito,M., Mayta,H., Nwaba,A., Ford-Siltz,L.A., Galeano,M.E.,
Zimic,M., Stupka,J.A., Gilman,R.H., Maneekarn,N., Ushijima,H.,
Green,K.Y. and Parra,G.I.
TITLE Direct Submission
JOURNAL Submitted (23-NOV-2020) CBER/OVRR/DVP/LHV, U.S. Food and Drug
Administration, 10903 New Hampshire Avenue, Silver Spring, MD
20993, USA
COMMENT ##Assembly-Data-START##
Assembly Method :: High-performance Integrated Virtual
Environment (HIVE) v. 2
Sequencing Technology :: Illumina
##Assembly-Data-END##
FEATURES Location/Qualifiers
source 1..7704
/organism="Norovirus GI"
/mol_type="genomic RNA"
/isolate="Arg4450"
/isolation_source="feces"
/host="Homo sapiens"
/db_xref="taxon:122928"
/country="Argentina"
/collection_date="2005"
/note="genotype: GI.3[GI.P3]"
gene <1..5367
/gene="ORF1"
CDS <1..5367
/gene="ORF1"
/codon_start=1
/product="nonstructural polyprotein"
/protein_id="QPJ58821.1"
/translation="ADVSNNNANTNNDNIGSRLMAKIRGRIGPQRGETTTKIKDANMA
LDLLRRSQTPSPSRQESPPKGQRDRPPRTASEVRRVMGWDVEPEHQESTAKAWCDLTQ
EEKEEIMRNNEKLFDAGGVTPSTLPSTFERAGPVDSPGEQQPVTWSASSGVDIGIDDL
TTVRGPFWNMCPLPPLDARNNGPAKEPLIGDMIEFYEGHIFHYAIYIGQGKTIGVHSP
QAAFSIPRITIHPLVAWWRVCYVPTNQQRLTYDQLKELENEPWPYASITNNCYEFCCR
VMALDDTWLERRLVSTGKFNHPTQDWSQDTPDFHQDSKLEMVRDAVLSAINGLVSQPF
KNILTKIKPLNVLNLLSNCDWTFMGVVELIVLLAELFDVFWTPPDISSFIASLLPEFH
LQGPEDLARDLVPLILGGIGLAIGFTRDKVTKVMKSAVDGLRSATQLGQYGLEIFSII
KKYFFGGDQTEKTLRGIEDAVIDMEVLSSTNVTQLVKDKKLARTYMNVLDNEEEKARK
LSVRSADPHIVTSVNNLISRISMARSALAKAQAEMTSRPRPVVIMMCGPPGIGKTKAA
EHLAGRLAAEIRPGGKVGLVPRESIDHWDGYHGEDVLLWDDYGMSKITEDCNKLQAIA
DTAPLSLNCDRIENKGMQFSSDAIIITTNAPGPAPVDFVNLGPVCRRVDFLVYCSAPE
IEQMRRTHPGDANAIKDLYKRDYSHLKMELAPQGGFDSQGNTPFGKGIMKPTTLNRLL
IQATALAMERQDEFQLQGAVYNFDEDRVSAFTSLARANGLGLVSMATLGKRLRSVKSM
EGLRNALVGYKIGECDIIWNTRVYSIKSDGSTVTIKEKQAPTSSQHQAICTATLALSR
LRAARALAYASCLQSAVLSILQVAGSALVVSRAVKRMFGTRTEQPMLEGKHKEHNCRV
HRAEAAGHGPIGHDGVIERYGLCESEQEEEGEQTVELPTANKEGKNKGKTKKGRGRKS
NFNAFSRRGLSDEEYEEYKKIREEKSGNYSIQEYLEDRQRYEEELAEVQAGGDGGIGE
TEAEIRHRVFYKSKSGMRKQRQEERRQLGLVSGSEIRKRKPIDWTPPKNDWSEDTRTV
NYDEHISFEAPPSIWSRVVKFGSGWGFWVSSTVFITTTHVIPPGAKEIFGENLGNVAI
HRVGEFTQFRFSKKMRPDLTGMVLEEGCPEGTVCTIMIKRDSGELLPLAVRMGAVASM
KIQGKLMHGQSGMLLTGANAKGMDLGTIPGDCGAPYVHKRGNDWVVCGVHAAATKSGN
TVVCAIQGGDGEATLEGGDQNKGHYAGHPILRYGNGPSLSTKTKFWKSTPQPLPPGTY
EPAYLGGRDPRVEGGPSLQQVLRDQLKPFAEPRGRLPEAGLLEAAVETVSNAIEQVMD
TPVAWSYSDACMSLDKTTSSGYPHHKKKNDDWNGNSFVRELGDQAAHANSMYELGKSM
KPVYTAALKDELVKPDKVYTKIKKRLLWGADLGTVIRAARAFGPFCEAIKSHVIKLPI
KVGMNAIEDGPLIYAEHSKYKFHYDADYTAWDSTQNREIMMESFNIMCKLTANPSLAA
VVAQDLLSPSEMDVGDYVISVKDGLPSGFPCTSQVNSINHWILTLCALSEVTGLSPDV
IQSQSYFSFYGDDEIVSTDIEFDPIRLTQVLKEYGLKPTRPDKTDGPIVVRQQVDGLV
FLRRTISKDAIGYQGRLDRNSIERQLWWTRGPNHEDPFETLVPHSQRKVQLISLLGEA
ALHGEKFYRKIASRVIQEVKEGGLEIYIPGWQAMFRWMRFHDLSLWTGDRNLLPDYVN
DDGV"
mat_peptide <1..1182
/gene="ORF1"
/product="p48"
mat_peptide 1183..2271
/gene="ORF1"
/product="NTPase"
mat_peptide 2272..2871
/gene="ORF1"
/product="p22"
mat_peptide 2872..3291
/gene="ORF1"
/product="VPg"
mat_peptide 3292..3834
/gene="ORF1"
/product="Pro"
mat_peptide 3835..5364
/gene="ORF1"
/product="RdRp"
gene 5351..6982
/gene="ORF2"
CDS 5351..6982
/gene="ORF2"
/note="major capsid protein"
/codon_start=1
/product="VP1"
/protein_id="QPJ58822.1"
/translation="MMMASKDAPTNMDGTSGAGQLVPEVSAAEPISMEPVAGAATAAA
TAGQVNMIDPWIMSNYVQAPQGEFTISPNNTPGDILFDLQLGPHLNPFLSHLAQMYNG
WVGNMKVRVLLAGNAFTAGKIIISCVPPGFAAQNISIAQATMFPHVIADVRVLEPIEV
PLEDVRNVLFHNNDSTPTMRLICMLYTPLRASGSSSGTDPFVIAGRVLTCPSPDFNFL
FLVPPNVEQKTKPFSVPNLPLNVLSNSRVPSLIKSMMVSQDHGQMVQFQNGRVTLDGQ
LQGTTPTSASQLCKIRGTVYHATGGQGLNLTEIDGTPYHAFESPAPIGFPDVGECDWH
INASPANTFTNGSIIQRIDVVQDSTFAPHLGTIHYTNANYDANVSLICSLEWLSPPSN
GAPKVNPWAIPRYGSTLTEAAQLAPPIYPPGFGEAIVFFMSDFPIANGSDGLSVPCTI
PQEFVTHFVNEQAPTRGEAALLHYVDPDTHRNLGEFKLYPEGFMTCVPNSSGSGPQTL
PINGVFTFISWVSRFYQLKPVGTTGPVRRLGIRRS"
gene 6982..7629
/gene="ORF3"
CDS 6982..7629
/gene="ORF3"
/note="minor structural protein; small basic protein"
/codon_start=1
/product="VP2"
/protein_id="QPJ58823.1"
/translation="MAQAIFGAIAATAAGSAVGAGIQAGTEAALQHQRFQQDLTLQSN
TFKHDKEMLGLQVGASTALLQNSLNTRYNMLTNAGLSSSDAARMVVGAPATRIVDWNG
TRVSAPRSTATTLRSGGFMTIPTLYKGKQQQKAPTEIGLSNPNYGSTVSSRVADWVSS
QNSSRSSLGPYHPNALQTAWVTPPGSSSTSTISSVSTAPRYFNTDRLPLFANMRK"
ORIGIN
1 gctgatgtca gcaataacaa tgctaacacc aacaatgata acattggatc ccgccttatg
61 gcgaagatcc gtgggcgtat aggcccacaa cgtggcgaaa caaccacaaa gataaaagat
121 gccaatatgg cacttgacct gttgcgccgg tcacagacac cttctccatc ccggcaagag
181 agccccccca agggccagag agaccgcccc cctcggaccg cctctgaggt gaggagagtg
241 atgggatggg atgttgaacc agaacatcaa gagagcacgg ccaaagcatg gtgtgatctc
301 acacaagaag agaaggagga gataatgcgc aacaatgaaa agctttttga tgctggggga
361 gttactccat caaccttacc tagcacattt gaaagagctg gcccagttga cagccccggt
421 gaacagcaac ctgtaacgtg gtctgccagt agtggggttg atatcggcat tgacgaccta
481 actactgttc gtggcccatt ctggaacatg tgtccccttc caccattgga tgcccggaac
541 aatggccccg ctaaagagcc cctcattggg gacatgatag agttttacga gggccacata
601 tttcattatg ccatctatat tggacagggt aagaccattg gggttcactc accgcaagca
661 gctttctcca tacctagaat aactattcat cctctagtgg cctggtggcg cgtgtgttat
721 gtcccaacta accaacagcg cctcacctat gaccaactca aagaattaga gaacgaacca
781 tggccctatg cctccatcac aaacaactgc tatgaattct gttgcagagt gatggcactt
841 gacgacacct ggcttgagag gaggctagtc agcacaggaa agttcaacca tcccacacaa
901 gattggtcac aggacacccc agatttccac caagattcta aacttgagat ggtgagagac
961 gctgtgctat cagctattaa tggccttgtg tcacaaccct tcaaaaacat tttaacaaag
1021 attaaaccat tgaatgttct caatctcttg tcaaattgtg attggacttt catgggggtt
1081 gtagaattaa ttgtactcct agcagagctt tttgatgtat tctggacccc accagatatt
1141 tcaagcttca ttgcctcatt actacctgaa ttccacctac agggcccaga agacctggct
1201 agggacttgg tccccctcat cttaggtggc ataggcctgg ctatcggctt tacaagagat
1261 aaagtgacaa aggtgatgaa gagcgccgtc gacgggctgc gatcggcaac acagcttggg
1321 cagtacggac tggagatatt ctcaatcatt aagaaatact tctttggtgg ggaccaaaca
1381 gaaaagacct tgcgaggtat agaggatgca gtgatagaca tggaagtgtt gtccagcact
1441 aatgtgacac aattagtcaa agataagaaa ctggctagaa catacatgaa tgtactggat
1501 aatgaagagg aaaaggcaag aaaactctca gtccgcagtg ctgacccaca catagtgacc
1561 tcagtcaaca acttgatatc acggatttcc atggcaagat cagccttggc taaagcccag
1621 gccgaaatga catctcgccc acgcccagtg gtcataatga tgtgtggccc tcccggcatc
1681 ggaaagacca aggccgccga gcacctggcc ggtcgattgg ccgctgaaat tagaccagga
1741 ggtaaggttg gtcttgtgcc ccgggagtcc atagaccact gggacggata tcatggtgag
1801 gatgtcttat tgtgggatga ttatggcatg tcaaagataa cagaggactg caacaagctg
1861 caggccatag ctgacactgc acccctatcg ctcaactgtg acaggataga gaacaaaggt
1921 atgcaattct cctcagatgc aataattata accactaatg ctcctggtcc tgccccagtg
1981 gactttgtca acctgggtcc tgtgtgcagg cgagtggact tcctagtcta ctgctctgcc
2041 cctgaaattg agcaaatgag aagaacccac cctggtgatg ccaatgctat taaggatctg
2101 tataaaagag actattcaca cttaaaaatg gaattggccc cacagggtgg ctttgatagt
2161 cagggtaaca caccatttgg gaaaggcatc atgaagccca caactctcaa taggctactc
2221 attcaggcaa cagcattggc tatggagcgg caagatgagt tccaactcca aggggctgtc
2281 tacaactttg atgaggatag ggtgtccgcc tttacaagcc tggcccgcgc caacggctta
2341 gggctcgtga gcatggcaac gctgggtaaa aggctcagaa gcgtcaagtc catggagggt
2401 ctgcgcaatg cattagtggg ctataagata ggagagtgtg acataatctg gaacaccagg
2461 gtgtattcaa tcaagagtga cggtagtacc gtcacaatta aagaaaaaca ggccccaacc
2521 tcctctcagc atcaggccat ctgcacagcc actctcgcgc tctctagatt gcgagctgcc
2581 agagctcttg cgtatgcctc ctgtctgcaa agtgcagtgc tatcaatact ccaggtggct
2641 ggctctgccc tagtggtgag tagggctgtg aaacgcatgt ttggcacacg cactgagcaa
2701 cctatgttag agggcaagca caaagagcac aactgtagag tgcaccgtgc agaagcagcc
2761 ggccatggcc ccattggaca tgatggggtc attgaacgct atggcttgtg tgagagtgag
2821 caagaagaag aaggtgagca aacggttgag ttaccaactg ccaataaaga aggtaaaaac
2881 aagggcaaga ccaaaaaggg ccgtgggcgg aaatccaact tcaacgcttt ctcaagacgc
2941 ggcctcagtg atgaagaata tgaagaatac aaaaagatta gagaagagaa aagtggtaac
3001 tacagcatcc aggagtacct cgaggatcgc cagcgttacg aggaagaact tgctgaagtg
3061 caggccggcg gggatggtgg aatcggtgag actgaggcgg agatccgcca tcgagttttc
3121 tacaagtcaa agtccggcat gaggaaacaa cgccaagaag agcggcgtca actgggcctc
3181 gtcagcggct ctgagattcg caagcgcaag cccatagact ggacccctcc taagaatgat
3241 tggtcagaag acaccagaac tgttaactat gatgaacaca tcagttttga ggcccctccc
3301 tcaatttgga gtagggtggt gaagtttggt agtggctggg gtttttgggt gagttcaaca
3361 gtgttcataa ctacaaccca tgttatacca cctggagcta aagaaatctt tggtgaaaac
3421 cttggcaatg tggccattca cagggttggt gaatttaccc aattccgctt ctccaaaaag
3481 atgaggcctg acctcactgg catggttcta gaagagggtt gcccagaagg aacagtgtgc
3541 actataatga tcaaaagaga ctctggtgag ctattgccac ttgctgttcg gatgggggca
3601 gtggcttcaa tgaagatcca aggtaaactt atgcatgggc agtcagggat gctgctcacc
3661 ggtgccaatg ccaaaggcat ggacctcgga actatacctg gtgactgtgg ggctccctat
3721 gtccacaaaa gaggaaacga ttgggtagta tgtggggtcc atgcggctgc cacaaaatca
3781 ggcaacactg tggtgtgtgc tatacagggt ggagacggtg aggccacgct ggagggtggc
3841 gaccaaaata agggacacta cgcagggcat ccaatattga gatatggaaa tggcccctcg
3901 ctgtcaacca agacaaaatt ctggaagtcc accccccagc cattgccccc cggcacatat
3961 gaaccagctt accttggtgg tagggaccct agagttgagg ggggcccatc cttacaacag
4021 gtgttaaggg accagttgaa accattcgcc gagccccgtg gcaggttacc cgaagcgggc
4081 ctgttggaag cagcagttga aacggtctct aatgcaattg aacaggtcat ggacacacca
4141 gtggcatgga gttatagtga cgcttgcatg tcactagaca agacaaccag ttccggttac
4201 cctcatcata aaaagaagaa tgatgattgg aatggaaatt catttgtgag agaactgggt
4261 gaccaggcgg cgcatgccaa tagcatgtat gaacttggca agtccatgaa gcctgtgtac
4321 acagcagccc tcaaagacga gctagtcaag ccagataagg tgtacactaa aatcaaaaag
4381 agattgcttt ggggcgcgga tcttggcacc gtcatccgcg ctgccagagc ttttgggcca
4441 ttctgtgaag ccataaaatc ccatgtaatc aaactgccta ttaaggtggg catgaacgcc
4501 atagaggatg gccctttgat ctatgcagag cactctaagt ataaattcca ctatgatgct
4561 gactacacag cttgggactc aacacaaaac agggagatca tgatggaatc ttttaacatt
4621 atgtgcaagc tcacagccaa cccttccttg gccgcagtag tggcacaaga tctgctctct
4681 ccatctgaaa tggacgttgg tgattatgtg atcagtgtta aagatggctt accatctggt
4741 ttcccatgca cttcacaagt gaatagcatc aaccactgga tcctgaccct atgtgcattg
4801 tcagaagtca ctggcttgtc ccctgatgtg atacaatcac agtcttattt ctcattttat
4861 ggtgatgatg agattgtttc aacagacata gagtttgacc caatcagatt aacacaagta
4921 ctgaaggagt atggtttgaa acccacaaga cctgataaaa ctgatggccc aattgttgtt
4981 agacagcagg tggatggcct ggttttcctc cgccgcacca tctctaagga tgccattggg
5041 taccagggac ggctcgaccg taactccatt gaaagacagc tttggtggac ccgcggacca
5101 aaccacgagg acccgtttga aacgctagtc ccacactcgc agaggaaggt tcagctgata
5161 tctctgctgg gtgaagcagc actccatggt gagaaattct ataggaaaat agccagtagg
5221 gtcattcaag aagtcaagga gggggggctt gaaatctaca tccctggttg gcaggccatg
5281 ttccgctgga tgcgattcca tgatttgagc ttgtggacag gagaccgcaa tctcctgccc
5341 gattatgtaa atgatgatgg cgtctaagga cgccccgaca aacatggatg gcaccagtgg
5401 tgccggtcag ctggttccag aggttagtgc agctgaacct atatcaatgg aacctgtggc
5461 tggtgctgct acggcagcag caaccgcagg ccaagttaat atgattgacc cctggattat
5521 gagtaattat gttcaagccc ctcaaggaga attcacaatt tcccctaaca atacccccgg
5581 ggacatattg tttgatttac agttaggccc tcatttaaac ccatttctat cacacctggc
5641 ccagatgtat aatgggtggg ttggcaatat gaaagtcaga gtgctgcttg ctggtaatgc
5701 ttttacagcg ggtaagataa taattagttg tgttccccca ggcttcgcag cccagaatat
5761 ttcaatagcc caagccacaa tgtttcctca cgttattgct gatgtacgag tgctagaacc
5821 gattgaggtc ccattagagg atgtgaggaa tgtgcttttc cataacaatg attccacccc
5881 aactatgaga ttgatttgta tgctgtacac ccctctccgt gccagtggta gttcttccgg
5941 cactgaccca tttgttatag ctggccgggt tctcacctgc cccagccctg atttcaactt
6001 tttgttcctt gtgcccccta atgttgagca gaaaactaag ccatttagtg tgcccaatct
6061 accccttaat gttctttcaa attctagagt tccctctttg ataaagtcca tgatggtctc
6121 ccaagaccat gggcagatgg tgcaattcca aaatggcagg gtcacattgg atgggcagct
6181 ccaaggcacc acccccactt cagccagtca actttgtaag attcggggga cggtctacca
6241 tgcaactggt ggccaagggc tcaacttgac tgagatagat ggtaccccct accatgcatt
6301 tgagagcccc gccccaattg gctttcccga tgtgggtgag tgtgattggc acattaatgc
6361 atctcctgcc aatactttta caaatggtag cattatacaa agaattgatg tggttcagga
6421 ttctactttt gccccccatc taggcactat ccattacacc aatgctaatt atgatgctaa
6481 tgttagtctg atttgctcgc ttgaatggct ttctccccca agtaatggtg ccccaaaggt
6541 aaatccatgg gctattcctc ggtatggttc aactctaact gaggctgctc agctggcccc
6601 accaatatac ccccctggtt ttggcgaggc aattgttttc tttatgtctg atttccccat
6661 agctaatggt tcagatggcc tgagtgtccc ttgcaccata ccacaagagt ttgtgaccca
6721 ttttgtcaat gagcaagcac caacccgtgg ggaagccgcc ctccttcatt atgttgaccc
6781 agatacacat cgcaatctgg gtgagttcaa attataccct gaaggattca tgacttgtgt
6841 gccaaactct agtggcagtg gtccccaaac gctgcccatc aatggggttt tcactttcat
6901 ttcttgggtt tcccgttttt accagttgaa gcctgtggga acgaccggac cggttcgtag
6961 gcttggaatc aggagatcat aatggcccaa gcaatatttg gagcaatagc tgcgacggct
7021 gctggcagtg ctgtaggtgc gggcatccaa gctggtactg aggctgcgct ccaacaccag
7081 cgctttcagc aggacttaac gttgcagagt aatactttta aacatgataa ggaaatgttg
7141 gggttgcagg ttggtgcctc cactgccctc ttacaaaata gtctcaacac ccgctacaac
7201 atgctcacta atgctggcct ctcgtcctcg gacgcagccc gcatggtggt tggcgcgcct
7261 gccacgcgta ttgtggactg gaatggcacc agagtatcgg caccacggtc cactgccacc
7321 acgctgaggt ctggtggttt catgacaatc ccaactttat acaaaggcaa acaacagcag
7381 aaagctccaa ctgaaattgg cttatctaac ccaaattatg ggtcaactgt atcttcaagg
7441 gttgctgatt gggtttcctc tcaaaattct tcccgttcgt ccttgggccc gtaccaccct
7501 aatgcattgc aaacagcatg ggtgacacca cctggctcaa gttctacctc tactatttct
7561 tctgtgtcta ccgcacctag atatttcaat actgataggt tgcctctatt cgcaaatatg
7621 agaaaatagt tttgtaatat gaaatgtggg catcatattc aattggattt gattaattgc
7681 taatctggtc taattatcaa tttg
//