Typing tool
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Typing tool
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Complete norovirus genomes
| MW305488 | GI.7 | |
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| GI.P7 |
ORF1: 1..5061
ORF2: 5045..6661
ORF3: 6661..7308
LOCUS MW305488 7322 bp RNA linear VRL 13-APR-2022
DEFINITION Norovirus GI isolate ONVHH1144 nonstructural polyprotein (ORF1)
gene, partial cds; and VP1 (ORF2) and VP2 (ORF3) genes, complete
cds.
ACCESSION MW305488
VERSION MW305488.1
KEYWORDS .
SOURCE Norovirus GI
ORGANISM Norovirus GI
Viruses; Riboviria; Orthornavirae; Pisuviricota; Pisoniviricetes;
Picornavirales; Caliciviridae; Norovirus; Norovirus norwalkense.
REFERENCE 1 (bases 1 to 7322)
AUTHORS Tohma,K., Lepore,C.J., Martinez,M., Degiuseppe,J.I., Khamrin,P.,
Saito,M., Mayta,H., Nwaba,A.U.A., Ford-Siltz,L.A., Green,K.Y.,
Galeano,M.E., Zimic,M., Stupka,J.A., Gilman,R.H., Maneekarn,N.,
Ushijima,H. and Parra,G.I.
TITLE Genome-wide analyses of human noroviruses provide insights on
evolutionary dynamics and evidence of coexisting viral populations
evolving under recombination constraints
JOURNAL PLoS Pathog 17 (7), e1009744 (2021)
PUBMED 34255807
REMARK Publication Status: Online-Only
REFERENCE 2 (bases 1 to 7322)
AUTHORS Tohma,K., Lepore,C.J., Martinez,M., Degiuseppe,J.I., Khamrin,P.,
Saito,M., Mayta,H., Nwaba,A., Ford-Siltz,L.A., Galeano,M.E.,
Zimic,M., Stupka,J.A., Gilman,R.H., Maneekarn,N., Ushijima,H.,
Green,K.Y. and Parra,G.I.
TITLE Direct Submission
JOURNAL Submitted (23-NOV-2020) CBER/OVRR/DVP/LHV, U.S. Food and Drug
Administration, 10903 New Hampshire Avenue, Silver Spring, MD
20993, USA
COMMENT ##Assembly-Data-START##
Assembly Method :: High-performance Integrated Virtual
Environment (HIVE) v. 2
Sequencing Technology :: Illumina
##Assembly-Data-END##
FEATURES Location/Qualifiers
source 1..7322
/organism="Norovirus GI"
/mol_type="genomic RNA"
/isolate="ONVHH1144"
/isolation_source="feces"
/host="Homo sapiens"
/db_xref="taxon:122928"
/geo_loc_name="Peru"
/collection_date="10-Oct-2013"
/note="genotype: GI.7[GI.P7]"
gene <1..5061
/gene="ORF1"
CDS <1..5061
/gene="ORF1"
/codon_start=1
/product="nonstructural polyprotein"
/protein_id="QPJ58800.1"
/translation="EEKKEILDNNERLFDAGGVTPSTVPSTFERCDTPERVDGCHPVK
WSESTGVDLGVDSLTTVTGPVWNMCPLPPIDSRNNGPASEPRIGDMIEFYEGHIFHYA
IYLGQGKTIGVHSPQAAFSIARITIHPMAAWWRVCYEPTDQQRLSYDQLKELENEPWP
YASVTNNCYEFCCRVMSLDDSWLQRKLVTSGRFNHPTQEWSKETPDFHQDSKLEIVRD
AILSAINGLVSQPFKNILSKIKPLNLLSLLSNCDWTFMGVVELVVLLAELFDIFWTPP
DISNFIASLLPDFHLQGPEDLARDLIPLILGGIGLAIGFTRDKITKVMKSAVDGLRSA
TQLGQYGLEVFSIIKKYFFGGDQTEKTLKGIENAVIDMEVLSSTNVTQLVRDKKLAKT
YMNILDNEEERARKLSVRSADPHVVTTVNNLISRISMARSALAKAQAEMTNRARPVVI
MMCGPPGIGKTKAAEHLANRLAGEIRPGGKVGLVPRESIDHWDGYHGEEVLLWDDYGM
SKITEDCNKLQAIADTAPLTLNCDRIENKGMQFVSDAIIITTNAPGPAPVDFVNLGPV
CRRVDFLVYCTAPEIEQTRRTHPGDTNAIKNLFKPDFSHLKMEIAPQGGFDNQGNTPF
GKGTMKSTTLSRLLIQAVALTMERQDEFQMQGAVYNFDEDRVTAFTSLARANGLGLLS
MAALGKKLRSVNNMEGLRNALKGYKITPCDIVWNNRTYTIKADGSNVSVTEKQAAVTL
QQQATSSVTLALSRLRAARALAYASCFQSAVTTILQMAGSAVVISRAVKRMFGTHTNQ
PALEGKPREHNCRVHRAEREGRGPIGHDGIIERYGLCETDQEEEEKIEMEVPTADKEG
KNKGKNKKGRGRKNNYNAFSRRGLSDEEYEEYKKVREEKGGNYSIQEYLEDRQRYEEE
LAEVQAGGDGGIGETEAEIRHRVFYKSKSGMRKQRQEERRQLGLVTGTEIRKRKPIDW
TPPKNDWSEDTRQVNYDEHISFEAPPSIWSRVVKFGSGWGFWVSSTVFITTTHVIPPD
AKEVFGEKLSDIAIHRVGEFTQFRFSKKMRPDLSGMVLEEGCPEGTVCTIMVKRDSGE
LLPLAVRMGAVASMKIQGKLMHGQSGMLLTGANAKGMDLGTIPGDCGAPYVHKRGNDW
IVCGVHAAATKSGNTVVCAIQSGEGEATLEGGGQNKGHYAGHPILRYGNGPSLSTKTK
FWKSTPQPLPPGTYEPAYLGGRDPRVDGGPSLQQVLRDQLKPFAEPRGRLPEPSLLEA
AVETVTNVLEQTMDTPVPWSFNDACMSLDKTTSSGYPHHKRKNDDWNGNAFVRELGEQ
AAHANNMYELGKSVKPVYTAALKDELVKPEKVYTKIKKRLLWGADLGTVIRAARAFGP
FCEAIKPHVIKLPIKVGMNAIEDGPLIYAEHAKYKYHFDADYTAWDSTQNREIMLESF
NIMCKLTANPSLAAVVAQDLLSPSEMDVGDYVISVKDGLPSGFPCTSQVNSINHWIYT
LCALSEVTGLAPDVLQSQSYFSFYGDDEIVSTDVEFDPIKLTQVLREYGLKPTRPDKS
EGPIIVKQQIDGLVFLRRTISKDAAGYQGRLDRNSIERQLWWTRGPNHDDPFETLIPH
QQRKIQLISLLGEAALHGEKFYRKIANRVIQEVKEGGLELYIPGWQAMFRWMRFHDLS
MWTGDRNLLPDYVNDDGV"
mat_peptide <1..876
/gene="ORF1"
/product="p48"
mat_peptide 877..1965
/gene="ORF1"
/product="NTPase"
mat_peptide 1966..2565
/gene="ORF1"
/product="p22"
mat_peptide 2566..2985
/gene="ORF1"
/product="VPg"
mat_peptide 2986..3528
/gene="ORF1"
/product="Pro"
mat_peptide 3529..5058
/gene="ORF1"
/product="RdRp"
gene 5045..6661
/gene="ORF2"
CDS 5045..6661
/gene="ORF2"
/note="major capsid protein"
/codon_start=1
/product="VP1"
/protein_id="QPJ58801.1"
/translation="MMMASKDAPSNMDGTSGAGQLVPEVNTAEPLPLEPVVGAATAAA
TAGQVNLIDPWIMNNFVQAPEGEFTISPNNTPGDILFDLRLGPHLNPFLLHLSQMYNG
WVGNMRVRVMLAGNAFSAGKIIICCVPPGFESQNISIGQATMFPHVIADVRVLEPIEI
PLDDVRNVLYHTNENRPTMRLLCMLYTPLRAGGASSGTDPFVIAGRVLTCPAPDFNFL
FLVPPSVEQKTRQLTIPNIPLNNLANSRVPAMINKMTVSADQNQVVQFQNGRCTLEGQ
LLGTTPVSANQVARIRGKVFSTNSGKGLNLTETDGTPYHAFESPAPLGFPDIGDCDWH
VYAFKVNQNTGDPMYRLDITQGNSFAPHLGSIEFTSDQHPSGDQLGTLTWISPLNNSS
RVDPWKIPSYGSTLTESTNLAPPIFPPGFGEAIVYFMSDFPIVSGNTTQIPCTLPQEF
ISSFVEQQAPIRGEAALLHYVDPDTHRNLGEFKLYPDGFITCVPNTGGGPQNLPSNGV
FIFSSWVSRYYQLKPVGTAGPARRLGVRRI"
gene 6661..7308
/gene="ORF3"
CDS 6661..7308
/gene="ORF3"
/note="minor structural protein; small basic protein"
/codon_start=1
/product="VP2"
/protein_id="QPJ58802.1"
/translation="MAQAIIGAIAATAAGSAVGAGIQAGTEAALQYQRFQQDLTLQEN
SFKHDERMLGLQIEGSNALLQKNLSTRYNLLVGAGLSSADAARSIAGAPVTKIVDWNG
VRIAAPTSTATTLRSGNFMSIPVTPKKEPQKLPARSVGLSNPNYDSSTMISRTTQWVE
SQNSIRNLSPFHSSALRTTWVTPPGSTSTSTFSTVSSAPRYFNTERLPLFANNRK"
ORIGIN
1 gaagaaaaga aggaaatcct ggacaacaac gagcgcctct ttgacgctgg cggcgtgact
61 ccctcgacag taccaagcac ttttgagagg tgtgatacac ctgagcgagt cgacggctgc
121 caccctgtca aatggagcga gtctacagga gtggatttgg gagtggattc tctgaccact
181 gttacaggtc cagtatggaa tatgtgcccc cttccaccaa ttgattcacg caacaatggc
241 ccagcaagtg aaccacgtat tggagatatg atagaatttt atgaagggca catattccat
301 tatgccatat atcttggtca agggaagacc ataggggtcc actctcctca ggcagctttt
361 tccatagctc gtataaccat acaccctatg gcagcatggt ggcgtgtctg ttatgagcca
421 acagatcaac aacgccttag ctatgaccaa ttaaaggaac ttgagaatga accgtggccc
481 tatgcatccg taacgaacaa ttgttacgag ttttgctgcc gtgtcatgtc cttggacgac
541 tcctggttac aacgaaagtt ggtgacatct ggcagattta atcatcccac ccaggaatgg
601 tccaaggaaa cacctgattt ccatcaagac tcaaaattgg aaatagtgag agacgcaata
661 ctatccgcca taaacggcct ggtctctcaa ccttttaaga acatcctctc aaaaattaaa
721 ccactaaatt tgttgtcttt gctatcaaac tgtgactgga cttttatggg ggtcgtcgag
781 ctagtagtgc tactggctga attgtttgac atcttctgga ccccacctga tatctctaat
841 tttatagcat ctctcctacc tgacttccac ctgcaagggc cagaggattt ggcaagagac
901 ctaatcccat taatactggg gggcatcggc ctggctattg gtttcactag agacaagatc
961 acgaaggtca tgaagagtgc cgttgatggt ctgcgctcag ccacgcagct tggacaatat
1021 ggccttgagg tgttctcgat tataaagaag tacttctttg gtggggatca aactgagaaa
1081 actctcaagg gcatagagaa tgcagtcata gacatggaag tcctgtcgag taccaatgtc
1141 acacaattgg tgcgcgacaa gaaattggct aaaacataca tgaatatcct ggacaatgaa
1201 gaggaaaggg caagaaaact ttcagtgcgc agtgctgacc cacatgttgt gacaacagtc
1261 aacaatctca tttcgcgcat atctatggcg cgatcagctc ttgccaaggc tcaagctgag
1321 atgactaatc gggcacgccc cgtggtcata atgatgtgtg ggccaccagg tataggaaaa
1381 accaaagctg ctgaacacct ggccaatcgc ctggctggtg agataaggcc aggaggaaaa
1441 gtgggcttag tgcctagaga atccattgac cattgggatg gctaccatgg ggaagaagtc
1501 ctgctgtggg atgactacgg catgtccaag ataacagagg attgcaataa actacaagcc
1561 atagctgaca ctgccccact cacactcaat tgtgacagaa tagagaacaa gggtatgcaa
1621 tttgtgtcag atgcaataat aataacaaca aatgcccccg ggccagcccc cgtcgacttt
1681 gttaaccttg gtccagtatg tcgacgtgta gacttcctgg tgtattgcac cgcccccgaa
1741 attgaacaga ccaggagaac ccatcctggg gacaccaatg ctatcaagaa cttgttcaaa
1801 ccagattttt cccatttaaa aatggagata gcaccacaag gggggtttga caatcaaggt
1861 aacaccccct ttgggaaggg tactatgaaa tcaaccacac tcagtaggtt gctcatccag
1921 gcagttgctt tgacaatgga gagacaagat gaattccaga tgcagggggc agtgtataac
1981 tttgatgagg accgggtcac agctttcact agcctagccc gggccaacgg gttaggactt
2041 ttgagtatgg ctgcactcgg taagaagttg cggagtgtca acaatatgga gggactccgc
2101 aacgccctca aagggtacaa gatcactcca tgtgacattg tgtggaacaa caggacttac
2161 accattaagg cagatggatc aaatgtgagc gtcacagaaa agcaggcagc tgtcactctc
2221 cagcaacaag ctaccagctc ggttactctg gcactttcta ggttacgcgc cgcgcgagcg
2281 ttggcgtatg catcatgttt ccagagcgca gtgaccacca tcttgcaaat ggctgggtct
2341 gcagtggtga tcagcagggc agtcaaacgc atgtttggga cccataccaa ccagccagcc
2401 ctagagggca aacccagaga acataactgc agggtccacc gagctgaaag agaaggtcgt
2461 ggccctattg gtcatgatgg catcatagaa cggtacggcc tgtgtgaaac tgaccaagaa
2521 gaagaagaga agatcgagat ggaagtgcca actgcagaca aagagggcaa gaataaaggc
2581 aagaacaaga aggggcgagg taggaaaaat aactacaacg ccttttctag gcgaggccta
2641 agtgatgagg agtatgaaga atacaagaag gtcagagaag aaaagggtgg taattacagc
2701 atccaagaat acctcgagga ccgccaaaga tatgaagagg agttggctga ggtccaagca
2761 ggtggagatg gcgggatcgg tgaaacagag gcagagatcc gccatcgtgt tttctacaaa
2821 tccaagagtg gcatgcgaaa acaacgccaa gaggagcgcc ggcagcttgg gttagtcaca
2881 ggcaccgaaa tcagaaagcg caagcccata gattggacac cacccaagaa tgactggtca
2941 gaagacacca gacaggtcaa ttatgatgaa cacatcagct ttgaagcccc accttctatt
3001 tggagtagag tggtcaaatt tggcagtgga tggggctttt gggtaagttc aacagtcttc
3061 atcacaacca cacacgtcat accaccagat gctaaagaag tctttgggga aaaactttca
3121 gatatagcaa tacacagagt tggagagttc acacaattta gattctctaa gaaaatgaga
3181 cctgatctta gtggtatggt ccttgaggag ggttgcccgg agggtacggt gtgcaccata
3241 atggtgaaga gagattcagg tgagctgttg cctctggctg tgcgcatggg agctgttgcg
3301 tccatgaaga tacaaggcaa gctcatgcat ggtcagtctg gtatgttgct aaccggtgca
3361 aatgcaaagg gaatggacct gggcaccatc cctggtgact gtggagctcc atatgtgcat
3421 aagaggggaa atgactggat agtgtgtgga gtgcacgcag ccgcaaccaa gtcgggcaac
3481 accgtagtgt gcgcaataca gtcaggtgaa ggtgaagcta cccttgaagg gggtggacaa
3541 aacaaagggc attatgcagg ccacccaatc ttaaggtatg gcaatgggcc ctctctctcc
3601 acaaaaacca aattctggaa atcaaccccc caaccgctcc cgcctggaac ctatgaacca
3661 gcttatctag gtgggcgtga ccccagagtg gacggtggtc catcacttca acaagtccta
3721 cgtgaccaac tcaagccttt tgctgagccc cgtggtaggc tgccagaacc gagcttgctc
3781 gaagcggccg tggagactgt tacaaatgtt ttagaacaaa ccatggacac acctgtgcct
3841 tggagcttca atgacgcctg tatgtctctt gacaagacca ccagctcagg ttatccgcac
3901 cataaacgca agaatgatga ttggaatggc aatgcgtttg tgcgtgaact tggggaacag
3961 gcggctcatg ccaataacat gtatgaattg ggtaagtcag tcaagccagt ttacacagca
4021 gcacttaaag atgaattggt gaaacctgaa aaagtgtata caaaaattaa aaagagactg
4081 ctttggggtg cggaccttgg cacagtcatt cgggccgctc gagccttcgg cccattctgt
4141 gaggcgataa aaccacatgt gataaaattg ccgatcaagg ttggcatgaa tgcaattgaa
4201 gatggccccc tcatatacgc tgaacacgca aagtataaat atcactttga tgcagattac
4261 acagcctggg actcaactca gaatagagag atcatgctgg aatctttcaa catcatgtgt
4321 aagctcacag ccaatccatc actggctgct gttgtggcac aggacctact gtctccatca
4381 gagatggatg tgggggatta tgtgatcagt gttaaggatg gcctcccctc agggttccca
4441 tgcacctcac aagtgaacag cataaaccat tggatttata ccctatgtgc cctatcagag
4501 gtcacaggcc tggcccctga tgttctgcaa tcccagtctt acttttcttt ctatggggat
4561 gatgagatag tgtcaactga tgttgaattt gacccaataa agctcaccca agtgctcaga
4621 gagtatggtt tgaagcccac ccgacctgat aaatcagaag ggcccatcat agtgaaacaa
4681 cagatagatg ggctggtctt cctcaggcgc actatatcaa aagacgctgc tggttaccag
4741 gggcgtttag atcgcaactc cattgaaagg caactgtggt ggactcgggg accaaaccat
4801 gacgacccct ttgagactct tataccccac caacagagga agattcagtt gatatccctg
4861 cttggtgaag ctgcactcca tggagagaaa ttttacagga agatagccaa tagggtgata
4921 caggaagtta aggagggagg gcttgagctc tacataccag gttggcaggc catgtttcgc
4981 tggatgcgat ttcatgactt gagcatgtgg acaggagatc gcaatctact gcctgattat
5041 gtaaatgatg atggcgtcta aggacgcccc ctcaaacatg gatggcacca gtggtgccgg
5101 tcagctggtt ccagaggtta atacagctga acctctaccc cttgaaccgg tggtgggcgc
5161 cgcaactgcg gcggccactg ctgggcaggt taatttaata gacccctgga tcatgaataa
5221 ttttgtccaa gcccctgaag gcgagttcac tatctcaccc aacaataccc ccggagatat
5281 tttatttgat ttgcgtctgg ggccacacct taaccccttc ctcctacatt tgtcccagat
5341 gtataatggt tgggttggga acatgagagt tagggtcatg cttgcaggga acgcgttctc
5401 tgctggtaag atcataattt gttgtgtccc acctggcttt gaatcccaga acatatcaat
5461 tggacaggcc actatgttcc cccatgtcat agctgatgta agagtcctgg agcccataga
5521 gatcccactt gatgatgtgc gcaacgtcct gtaccacaca aatgagaacc gcccaaccat
5581 gcgattgctc tgcatgttgt acacacctct ccgtgccgga ggggcttcat caggcacaga
5641 tccttttgtc attgctggcc gtgtgttgac ttgccctgcc cctgacttta attttctgtt
5701 tcttgtgccc cccagtgtag aacagaaaac caggcaactg actataccca atataccctt
5761 gaataatttg gctaactcca gagtgcctgc aatgataaat aagatgacag tctctgctga
5821 tcagaatcag gtggtccagt ttcaaaatgg ccgttgcaca cttgaaggac aactcttagg
5881 tacaactcct gtttcagcca accaagttgc ccgcatacgt ggtaaagtct tctctaccaa
5941 ctccggaaag ggacttaatt taactgaaac agatggaacc ccctaccatg catttgagag
6001 cccggcccct ctcggttttc ctgacatagg tgattgtgat tggcatgtgt atgcttttaa
6061 ggtgaatcaa aatacagggg atcccatgta cagattggat ataacacaag gaaactcatt
6121 tgcgccgcat cttggttcca tcgagttcac ttctgatcag cacccatcag gagatcaatt
6181 aggcacactt acttggatct cccctctcaa caattcctcc agggttgacc cctggaaaat
6241 cccatcatat ggttcaacat tgactgagtc cactaacctg gcaccgccca tctttccacc
6301 aggctttggt gaggccatag tctacttcat gtcagatttc cctattgtgt caggtaacac
6361 tacccaaatc ccctgcaccc tgccccaaga gttcatctca tcctttgtgg aacaacaggc
6421 acccatccga ggtgaggctg ctctactgca ttatgtggac ccagacaccc atcgcaattt
6481 gggagaattc aaactgtacc ctgatgggtt catcacttgt gtgccaaaca cgggtggcgg
6541 tccccaaaac ctcccttcaa atggtgtttt tatcttttct tcttgggtct ctagatatta
6601 ccaattgaag cctgtgggaa cagccggtcc ggctaggcgg cttggtgtga gaaggatata
6661 atggctcaag ccattatagg agctattgcc gccaccgctg ctggcagcgc agtgggggca
6721 ggaatccaag ctggaactga ggcagccttg caataccaaa ggttccaaca agacctcacc
6781 ctgcaggaga attcttttaa acatgatgaa aggatgttgg gtttacaaat tgaggggtct
6841 aatgctttgc tacaaaagaa tctttctact cgctataatc ttttagttgg tgcaggtctt
6901 tcctcagctg atgccgcaag gtctattgct ggagccccag tgacaaaaat cgtggactgg
6961 aatggggtga gaattgctgc ccctacatcc actgccacca ctctccgttc tggcaacttc
7021 atgagcatac cagttacacc taaaaaggag ccccaaaaat tgccagcacg ttctgtgggc
7081 ctctccaatc ctaattatga ttcatccact atgatttcta ggacaactca atgggtggaa
7141 tcgcaaaatt caatcaggaa tttgtcacct ttccatagct ctgctttgag gactacttgg
7201 gtaacccctc ctggttctac ttctacttca accttttcta ctgtttcttc ggcgccacga
7261 tattttaaca ccgagcgcct tcctttgttc gcaaacaata ggaaatagtt tttgtaatat
7321 aa
//