Typing tool
|
|
|
|
|
|
Typing tool
|
Complete norovirus genomes
| MW305483 | GI.7 | |
|
|---|---|---|---|
| GI.P7 |
ORF1: 1..5062
ORF2: 5046..6662
ORF3: 6662..7309
LOCUS MW305483 7323 bp RNA linear VRL 13-APR-2022
DEFINITION Norovirus GI isolate PNV027757 nonstructural polyprotein (ORF1)
gene, partial cds; and VP1 (ORF2) and VP2 (ORF3) genes, complete
cds.
ACCESSION MW305483
VERSION MW305483.1
KEYWORDS .
SOURCE Norovirus GI
ORGANISM Norovirus GI
Viruses; Riboviria; Orthornavirae; Pisuviricota; Pisoniviricetes;
Picornavirales; Caliciviridae; Norovirus; Norovirus norwalkense.
REFERENCE 1 (bases 1 to 7323)
AUTHORS Tohma,K., Lepore,C.J., Martinez,M., Degiuseppe,J.I., Khamrin,P.,
Saito,M., Mayta,H., Nwaba,A.U.A., Ford-Siltz,L.A., Green,K.Y.,
Galeano,M.E., Zimic,M., Stupka,J.A., Gilman,R.H., Maneekarn,N.,
Ushijima,H. and Parra,G.I.
TITLE Genome-wide analyses of human noroviruses provide insights on
evolutionary dynamics and evidence of coexisting viral populations
evolving under recombination constraints
JOURNAL PLoS Pathog 17 (7), e1009744 (2021)
PUBMED 34255807
REMARK Publication Status: Online-Only
REFERENCE 2 (bases 1 to 7323)
AUTHORS Tohma,K., Lepore,C.J., Martinez,M., Degiuseppe,J.I., Khamrin,P.,
Saito,M., Mayta,H., Nwaba,A., Ford-Siltz,L.A., Galeano,M.E.,
Zimic,M., Stupka,J.A., Gilman,R.H., Maneekarn,N., Ushijima,H.,
Green,K.Y. and Parra,G.I.
TITLE Direct Submission
JOURNAL Submitted (23-NOV-2020) CBER/OVRR/DVP/LHV, U.S. Food and Drug
Administration, 10903 New Hampshire Avenue, Silver Spring, MD
20993, USA
COMMENT ##Assembly-Data-START##
Assembly Method :: High-performance Integrated Virtual
Environment (HIVE) v. 2
Sequencing Technology :: Illumina
##Assembly-Data-END##
FEATURES Location/Qualifiers
source 1..7323
/organism="Norovirus GI"
/mol_type="genomic RNA"
/isolate="PNV027757"
/isolation_source="feces"
/host="Homo sapiens"
/db_xref="taxon:122928"
/geo_loc_name="Peru"
/collection_date="12-Jul-2010"
/note="genotype: GI.7[GI.P7]"
gene <1..5062
/gene="ORF1"
CDS <1..5062
/gene="ORF1"
/codon_start=2
/product="nonstructural polyprotein"
/protein_id="QPJ58785.1"
/translation="EEKKEILDNNERLFDAGGVTPSTVPSTFERCETSERVDGCHPVK
WSESAGVDLGVDSLITVTGPVWNMCPLPPIDSRNNGPAGEPRIGDMIEFYEGHIFHYA
IYLGQGKTIGVHSPQAAFSIARITIHPMAAWWRVCYEPTDQQRLSYDQLKELENEPWP
YASITNNCYEFCCRVMSLDDTWLQRKLVTSGRFNHPTQEWSKETPDFHQDSKLEIVRD
AILSAINGLVSQPFKNILSKIKPLNLLSLLSNCDWTFMGVVELVVLLAELFDIFWTPP
DISNFIASLLPDFHLQGPEDLARDLVPLILGGIGLAIGFTRDKITKVMKSAVDGLRSA
TQLGQYGLEVFSIIKKYFFGGDQTEKTLKGIENAVIDMEVLSSTNVTQLVRDKKLAKT
YMNILDNEEERARKLSVRSADPHVVTTVNNLISRISMARSALAKAQAEMTNRARPVVI
MMCGPPGIGKTKAAEHLANRLAGEIRPGGKVGLVPRESIDHWDGYHGEEVLLWDDYGM
SKITEDCNKLQAIADTAPLTLNCDRIENKGMQFVSDAIIITTNAPGPAPVDFVNLGPV
CRRVDFLVYCTAPEIEQTRRAHPGDTNAIKNLFKPDFSHLKMEIAPQGGFDNQGNTPF
GKGAMKSTTLNRLLIQAVALTMERQDEFQMQGAVYNFDEDRVTAFTNLARANGLGLLS
MAALGKKLRSVNNMEGLRNALKGYKITECDIVWNNRTYTVKGDGSNVSVTEKQAAATL
QQQAISSVTLALSRLRAARALAYASCLQSAVTTILQMAGSAVVISRAVKRMFGTHTNQ
PALEGKPREHNCRVHRAEREGRGPIGHDGIIERYGLCETDQEEEEKIEMEVPTADKEG
KNKGKNKKGRGRKNNYNAFSRRGLSDEEYEEYKKVREEKGGNYSIQEYLEDRQRYEEE
LAEVQAGGDGGIGETEAEIRHRVFYKSKSGMRKQRQEERRQLGLVTGTEIRKRKPIDW
TPPKNDWSEDTRQVNYDEHISFEAPPSIWSRVVKFGSGWGFWVSSTVFITTTHVTPPD
AKEIFGEKLSDIAIHRVGEFTQFRFSKKMRPDLSGMILEEGCPEGTVCTIMVKRDSGE
LLPLAVRMGAVASMKIQGKLMHGQSGMLLTGANAKGMDLGTIPGDCGAPYVHKRGNDW
VVCGVHAAATKSGNTVVCAIQSGEGEATLEGGGQNKGHYAGHPILRYGNGPSLSTKTK
FWKSTPQPLPPGTYEPAYLGGRDPRVDGGPSLQQVLRDQLKPFAEPRGRLPEPSLLEA
AVETVTNVLEQTMDTPVPWSYSDACMSLDKTTSSGYPHHKRKNDDWNGNAFVRELGEQ
AAHANNMYELGKSVKPVYTAALKDELVKPEKVYTKIKKRLLWGADLGTVIRAARAFGP
FCEAIKPHVIKLPIKVGMNAIEDGPLIYAEHAKYRYHFDADYTAWDSTQNREIMLESF
NIMCKLTANPSLAAVVAQDLLSPSEMDVGDYVISVKDGLPSGFPCTSQVNSINHWIYT
LCALSEVTGLAPDVLQSQSYFSFYGDDEIVSTDVEFDPIKLTQVLREYGLKPTRPDKS
EGPIIVKQQIDGLVFLRRTISKDAAGYQGRLDRNSIERQLWWTRGPNHNDPFETLIPH
QQRKIQLISLLGEAALHGEKFYRKIANRVIQEVKEGGLELYIPGWQAMFRWMRFHDLS
MWTGDRNLLPDYVNDDGV"
mat_peptide <1..877
/gene="ORF1"
/product="p48"
mat_peptide 878..1966
/gene="ORF1"
/product="NTPase"
mat_peptide 1967..2566
/gene="ORF1"
/product="p22"
mat_peptide 2567..2986
/gene="ORF1"
/product="VPg"
mat_peptide 2987..3529
/gene="ORF1"
/product="Pro"
mat_peptide 3530..5059
/gene="ORF1"
/product="RdRp"
gene 5046..6662
/gene="ORF2"
CDS 5046..6662
/gene="ORF2"
/note="major capsid protein"
/codon_start=1
/product="VP1"
/protein_id="QPJ58786.1"
/translation="MMMASKDAPSNMDGTSGAGQLVPEVNAAEPLPLEPVVGAATAAA
TAGQVNMIDPWIMNNFVQAPEGEFTISPNNTPGDVLFDLRLGPHLNPFLLHLSQMYNG
WVGNMRVRVMLAGNAFSAGKIIICCVPPGFESQNISIGQATMFPHVIADVRVLEPIEI
PLDDVRNVLFHTNENRPTMRLLCMLYTPLRAGGASSGTDPFVIAGRVLTCPAPDFNFL
FLVPPSVEQKTRQLTIPNIPLNNLANSRVPAMINKMTVSADQNQVVQFQNGRCTLEGQ
LLGTTPVSANQVARIRGKVFSTNSGTGLNLTEIDGTPYHAFESPAPLGFPDIGDCDWH
VYAFKVNQNTGDPMYRLDITQGNSFAPHLGSIEFSSEQHPSGDQLGTLTWISPLNNAS
RVDPWKIPSYGSTLTESTNLAPPIFPPGFGEAIVYFMSDFPIVSGNTAQIPCTLPQEF
VSSFVEQQAPIRGEAALLHYVDPDTHRNLGEFKLYPDGFITCVPNTGGGPQNLPSNGV
FIFSSWVSRYYQLKPVGTTGPVRRLGVRRV"
gene 6662..7309
/gene="ORF3"
CDS 6662..7309
/gene="ORF3"
/note="minor structural protein; small basic protein"
/codon_start=1
/product="VP2"
/protein_id="QPJ58787.1"
/translation="MAQAIIGAIAATAAGSAVGAGIQAGTEAALQYQRFQQDLTLQEN
SFKHDEKMLGLQIEGSNALLQKNLSTRYNLLVGAGLSSADAARSIAGAPMTKLVDWNG
VRIAAPASTATTLRSGNFMSIPVTPKKEPQKLSARSVGLSNPNYDSSTMISRTTQWVE
SQNSIRNLSPFHSSALRTTWVTPPGSTSTSTFSIASSAPRYFNTERLPLFANNRK"
ORIGIN
1 ggaagaaaag aaggagatcc tggacaacaa cgagcgcctc tttgacgctg gcggtgtgac
61 tccttcgaca gtaccaagca cttttgagag atgtgaaaca tctgagcgag tcgacggctg
121 ccaccctgtc aaatggagcg agtctgcggg agtggattta ggcgtggatt ctctaatcac
181 tgtcacaggt ccagtgtgga acatgtgccc ccttccaccg attgattcac gtaacaatgg
241 ccctgcaggt gagccacgca ttggagacat gatagaattt tatgaagggc atatattcca
301 ttacgccata tatcttggtc aagggaagac cataggagtc cactcccctc aggcagcttt
361 ctccatagct cgtataacca tacaccctat ggcagcatgg tggcgtgtct gctatgaacc
421 aacagatcag caacgcctca gctatgacca attaaaggaa cttgagaatg aaccgtggcc
481 ctacgcatcc ataacgaata attgttatga gttctgctgc cgtgtcatgt ccctggacga
541 cacctggtta caacgaaagt tggtgacatc cggtaggttt aatcacccca cccaggagtg
601 gtccaaggaa acacctgatt tccatcaaga ttcaaaattg gaaatagtga gagacgcaat
661 actatccgcc ataaacggct tggtctctca accttttaag aatatcctct caaaaattaa
721 gccactgaat ctgttgtctt tgctatcaaa ttgtgactgg actttcatgg gggtcgtcga
781 gctagtggtg ctactggctg aactgtttga catattctgg accccacctg atatctccaa
841 cttcatagca tctctcctgc ctgactttca cctgcaaggg ccagaggatt tggcgagaga
901 cctggtccca ttaatattgg ggggtattgg cctggctatt ggcttcacca gagacaaaat
961 cacaaaggtc atgaagagtg ccgttgatgg cctgcgctca gccacgcagc ttggacaata
1021 tggccttgag gtgttctcga tcataaagaa gtatttcttt ggtggggacc aaactgagaa
1081 aaccctcaag ggcatagaga atgcagtcat agatatggaa gtcctgtcga gtaccaatgt
1141 cacacaactg gtgcgcgaca agaagttggc caaaacatac atgaatatcc tggacaatga
1201 ggaggaaagg gcaaggaaac tttcagtgcg cagtgcagat ccacatgttg tgacaacagt
1261 caacaacctc atttcgcgca tatctatggc gcgatcagct ctcgccaaag ctcaggctga
1321 gatgactaat cgggcacgcc ccgtggtcat aatgatgtgt ggaccaccag gtataggaaa
1381 aaccaaagct gctgaacacc tggccaatcg cctggctggt gagataagac cagggggaaa
1441 agtgggttta gtgcctagag aatccattga ccactgggac ggctaccatg gggaagaagt
1501 cctgttatgg gatgactacg gcatgtccaa gataacagag gattgcaata aactacaagc
1561 catagctgac actgctccac tcacactcaa ttgtgacagg atagagaaca agggtatgca
1621 atttgtgtca gatgcaataa taataacaac aaatgccccc gggccagccc ccgtcgactt
1681 tgttaacctt ggtccagtgt gtcgacgcgt agacttcttg gtgtattgca ctgcccccga
1741 aattgaacaa accaggagag cccaccctgg ggacaccaat gctatcaaga atttgttcaa
1801 accagatttt tcccatttaa aaatggagat agcaccacaa ggggggtttg acaatcaagg
1861 taacaccccc tttgggaagg gtgctatgaa atcgaccaca ctcaataggc tactcataca
1921 ggcagtcgct ttgacaatgg aaagacaaga tgagttccag atgcaggggg cagtgtataa
1981 ctttgatgag gatcgggtca cagccttcac taacctggcc cgggccaacg gactaggact
2041 tttgagcatg gccgcactcg gtaaaaagtt gcggagcgtc aacaatatgg aaggactccg
2101 caacgccctc aaagggtaca agatcactga atgtgacatt gtgtggaaca acaggactta
2161 caccgttaag ggagatggat caaatgtgag cgtcacagaa aagcaggcag ctgccactct
2221 tcagcaacaa gccatcagct ctgttactct ggcactttct aggttacgcg ccgcacgagc
2281 gttggcgtat gcatcatgtc tccagagcgc agtaaccacc atcttgcaaa tggctgggtc
2341 tgcagtggtg atcagcaggg cagtcaaacg catgtttggg acccacacca accagccagc
2401 actggagggc aaacccaggg aacacaactg cagggtccac cgtgccgaaa gggaaggtcg
2461 tggccctatt ggtcatgatg gcatcataga acggtacggt ctgtgtgaga ctgatcaaga
2521 agaagaagaa aagatcgaga tggaagtgcc aactgcagac aaggaaggca agaacaaagg
2581 caagaacaag aaggggcgag gtaggaaaaa taactacaac gccttctcta ggcgaggcct
2641 aagtgatgag gagtatgaag aatacaagaa ggttagagaa gagaagggtg gtaactacag
2701 catccaagaa tacctcgagg accgccaacg atatgaagaa gagttggctg aggtccaagc
2761 gggtggagat ggcgggatcg gtgaaacaga ggcagagatc cgccatcgtg ttttctataa
2821 atccaagagt ggcatgcgaa aacaacgtca agaggagcgc cgacagcttg gattagtcac
2881 aggcactgaa atcagaaagc gcaagcccat agattggaca ccacctaaga atgactggtc
2941 agaagacacc aggcaggtca actatgatga gcacatcagc ttcgaagccc caccttctat
3001 ttggagtaga gtggtcaaat ttggcagtgg atggggcttt tgggtgagtt caacagtttt
3061 tatcacaacc acacacgtca caccaccaga tgctaaagaa atctttgggg aaaaactttc
3121 agatatagca atacacagag ttggggagtt cacacaattt agattctcta agaaaatgag
3181 acctgacctc agtggcatga tccttgagga gggttgcccg gagggaacgg tgtgcactat
3241 aatggtgaag agagattcag gtgaactgtt acctctagct gtgcgcatgg gagctgttgc
3301 atccatgaag atacaaggta agctcatgca tggtcaatct ggtatgttgc taaccggtgc
3361 aaatgcaaag ggaatggacc ttggcaccat ccctggtgac tgtggagctc catatgtgca
3421 taagagggga aatgactggg tagtgtgtgg agtgcacgca gccgcaacca agtcgggcaa
3481 caccgtggtg tgtgcaatac agtcaggtga aggtgaagct acccttgaag ggggcggaca
3541 aaacaaggga cattatgcag gccacccaat tttaaggtat ggcaatgggc cctctctctc
3601 cacaaaaacc aaattctgga aatcgacccc ccaaccactc ccgcctggaa cctatgaacc
3661 agcttaccta ggtggacgtg accccagggt agacggtggt ccatctcttc aacaagttct
3721 acgtgatcaa ctcaagcctt ttgctgagcc ccgtggtaga ctgccagaac cgagcttgct
3781 cgaagcagct gtggagactg ttacaaatgt tttagaacaa accatggaca cacctgtgcc
3841 ttggagttac agtgacgcct gtatgtctct tgacaagacc accagctcag gttatccgca
3901 ccataagcgc aagaatgatg attggaatgg caatgcgttt gtgcgtgaac ttggggaaca
3961 agcagctcat gccaataata tgtacgaatt gggcaagtca gttaaaccag tttacacagc
4021 agcacttaaa gatgaactgg taaaacctga aaaagtgtac acaaaaataa aaaagagact
4081 gctttggggt gcggaccttg gtacagtcat tcgggccgct cgagccttcg gcccattttg
4141 tgaggcgata aagccacatg tgataaaatt gccaatcaag gttggcatga atgcaattga
4201 agatggcccc ctcatatatg ctgaacatgc aaagtataga tatcattttg atgcagatta
4261 cacagcttgg gactcaactc agaatagaga aatcatgcta gaatctttca acattatgtg
4321 taagctcaca gccaatccat cactggccgc tgttgtggca caggacctac tgtccccatc
4381 agaaatggat gtgggggatt atgtgattag tgttaaggat ggcctcccct cagggttccc
4441 atgcacctca caagtgaaca gcataaacca ctggatttac actctgtgtg ccctgtcaga
4501 ggtcacaggc ttggcccctg atgtcctgca atcccagtct tacttttcct tttacgggga
4561 tgatgagata gtgtcaactg atgtggaatt tgacccaata aagctcaccc aagtgctcag
4621 agaatatggt ttgaagccca cccgacctga caaatcagaa gggcccatta tagtgaaaca
4681 acagatagat gggctggtct ttctcagacg tactatatca aaagatgctg ctggttacca
4741 ggggcgttta gaccgcaact ccattgaaag gcagttgtgg tggactcggg gaccaaatca
4801 taatgacccc tttgagactc tgatacccca tcaacaaagg aaaattcaac tgatatccct
4861 gcttggtgag gctgcactcc atggagagaa attttacagg aagattgcta atagggtgat
4921 acaggaagtt aaggagggtg ggcttgagct ctacatacca ggttggcagg ccatgttccg
4981 ctggatgcga tttcatgact tgagcatgtg gacaggagat cgcaatctac tgcctgatta
5041 tgtaaatgat gatggcgtct aaggacgccc cctcaaacat ggatggcacc agtggtgccg
5101 gtcagctggt tccagaggtt aatgcagctg aacctctacc ccttgaaccg gtggtgggcg
5161 ccgcaaccgc ggcggccact gctggacagg ttaatatgat agacccctgg attatgaata
5221 attttgtcca agcccctgaa ggcgaattta ctatttcacc caacaatacc cctggagatg
5281 ttttatttga tttgcgtctg ggaccacacc ttaacccctt tctcctgcat ttgtctcaga
5341 tgtataatgg ttgggttggg aacatgagag ttagggtcat gcttgcgggg aacgcgttct
5401 ccgctggtaa gatcataatt tgttgtgtcc cacctggctt tgaatcccag aacatatcaa
5461 ttggacaagc cacaatgttc ccccatgtca tagctgatgt gagagttctg gagcccatag
5521 agatccccct tgatgatgtg cgcaatgtcc tgttccacac aaatgagaac cgcccaacca
5581 tgcgactgct ctgtatgtta tacacacctc tccgtgctgg aggagcttca tcaggcacag
5641 atccttttgt cattgctggc cgtgtgttaa cttgtcccgc tcctgatttc aattttctgt
5701 ttcttgtgcc ccccagtgta gaacagaaaa ccaggcaatt gactataccc aatataccct
5761 tgaacaattt ggctaactcc agagtgcctg caatgataaa caagatgaca gtctctgctg
5821 accagaatca ggtggtccag tttcaaaatg gccgttgcac acttgaggga caactcttag
5881 gtacaacccc tgtttcagcc aaccaagttg cccgcatacg tggcaaagtc ttctccacca
5941 actccgggac ggggcttaat ttaactgaaa tagatggaac cccctaccat gcatttgaga
6001 gcccggcccc cctcggtttt cctgacatag gtgattgtga ttggcacgtg tatgccttta
6061 aggtaaatca aaatacaggg gatcccatgt acagattgga tataacacaa ggaaactcat
6121 ttgcaccgca tcttggctcc attgagttta gttctgaaca gcacccatcg ggggaccaac
6181 taggcacact tacttggatc tcccctctca acaacgcttc tagggttgac ccctggaaaa
6241 tcccatcata tggttcaaca ttgactgagt ccaccaactt ggcaccaccc atctttccac
6301 caggttttgg tgaggctata gtttatttta tgtcagattt tcctattgtg tcaggtaata
6361 ctgcccaaat cccctgcacc ctgccccaag aatttgtttc atcttttgtg gaacaacagg
6421 caccgatccg aggtgaagct gccctactgc attatgtgga cccagatacc catcgcaatc
6481 tgggagaatt caaattgtac cctgatgggt tcatcacttg tgtgccaaac acgggtggcg
6541 gcccccaaaa tctcccatcg aatggtgtct ttatcttctc ttcttgggtt tctagatatt
6601 atcaattaaa gcctgtggga acaaccggtc cggttaggag gcttggtgtg agaagggtat
6661 aatggcccaa gccatcatag gagctattgc cgccaccgct gctggcagcg cagtgggggc
6721 aggtatccaa gctggaactg aggcagcctt gcaataccaa aggtttcagc aagatctcac
6781 cctgcaggaa aattctttca agcatgatga aaagatgttg ggtctacaaa ttgaggggtc
6841 taatgctttg ctacaaaaga atctctctac ccgctataat cttttagttg gtgcaggtct
6901 ttcctcagct gatgctgcaa gatccattgc tggggcccca atgacaaagc tcgtggactg
6961 gaatggggtg agaatcgccg cccccgcgtc cactgccacc accctccgtt ctggcaactt
7021 catgagcata ccagtcacac ccaaaaagga gccccaaaaa ctgtcagcac gatctgtagg
7081 cctctccaat cctaattatg attcatctac tatgatttct aggacaactc aatgggtgga
7141 gtcgcaaaat tcaatcagga atttgtcacc tttccatagc tcggctctga ggactacttg
7201 ggtaactcct cctggttcta cttctacttc aactttttct attgcttctt cggcgccacg
7261 gtacttcaac accgagcgtc ttcctttgtt cgcaaacaat aggaaatagt ttttgtaata
7321 taa
//