Typing tool
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Typing tool
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Complete norovirus genomes
| MW261799 | GIX.1 | |
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| GII.P15 |
ORF1: 1..5065
ORF2: 5046..6713
ORF3: 6713..7435
LOCUS MW261799 7506 bp RNA linear VRL 13-APR-2022
DEFINITION Norovirus GIX isolate DS357 nonstructural polyprotein (ORF1) gene,
partial cds; and VP1 (ORF2) and VP2 (ORF3) genes, complete cds.
ACCESSION MW261799
VERSION MW261799.1
KEYWORDS .
SOURCE Norovirus GIX
ORGANISM Norovirus GIX
Viruses; Riboviria; Orthornavirae; Pisuviricota; Pisoniviricetes;
Picornavirales; Caliciviridae; Norovirus; Norwalk virus.
REFERENCE 1 (bases 1 to 7506)
AUTHORS Tohma,K., Lepore,C.J., Martinez,M., Degiuseppe,J.I., Khamrin,P.,
Saito,M., Mayta,H., Nwaba,A.U.A., Ford-Siltz,L.A., Green,K.Y.,
Galeano,M.E., Zimic,M., Stupka,J.A., Gilman,R.H., Maneekarn,N.,
Ushijima,H. and Parra,G.I.
TITLE Genome-wide analyses of human noroviruses provide insights on
evolutionary dynamics and evidence of coexisting viral populations
evolving under recombination constraints
JOURNAL PLoS Pathog 17 (7), e1009744 (2021)
PUBMED 34255807
REMARK Publication Status: Online-Only
REFERENCE 2 (bases 1 to 7506)
AUTHORS Tohma,K., Lepore,C.J., Martinez,M., Degiuseppe,J.I., Khamrin,P.,
Saito,M., Mayta,H., Nwaba,A., Ford-Siltz,L.A., Galeano,M.E.,
Zimic,M., Stupka,J.A., Gilman,R.H., Maneekarn,N., Ushijima,H.,
Green,K.Y. and Parra,G.I.
TITLE Direct Submission
JOURNAL Submitted (16-NOV-2020) CBER/OVRR/DVP/LHV, U.S. Food and Drug
Administration, 10903 New Hampshire Avenue, Silver Spring, MD
20993, USA
COMMENT ##Assembly-Data-START##
Assembly Method :: High-performance Integrated Virtual
Environment (HIVE) v. 2
Sequencing Technology :: Illumina
##Assembly-Data-END##
FEATURES Location/Qualifiers
source 1..7506
/organism="Norovirus GIX"
/mol_type="genomic RNA"
/isolate="DS357"
/isolation_source="feces"
/host="Homo sapiens"
/db_xref="taxon:2594528"
/country="Saudi Arabia"
/collection_date="1990"
/note="genotype: GIX.1 [GII.P15]"
gene <1..5065
/gene="ORF1"
CDS <1..5065
/gene="ORF1"
/codon_start=2
/product="nonstructural polyprotein"
/protein_id="QPC96810.1"
/translation="FGSQKATNDSYSTPPPNKEETSVLTNVKVGFKKILGAVPKASRQ
HGNIQKPPIVEIDGVAMRVPSPPPNGEDAVHFVKETETIKGLPDLSTVENESEHSPYT
VPPLSEREHRPATEPLPGTILEMWDGEFYHYSIYVDNGKALGVHKPPAAISLATIDLT
PISLYWRPVYTPPYLVHPETLKGLAGEKFPYTAFSNNCYNFCCWVLDLNDSWLNRRSI
NRTTGFFKPYQTWNRKPLPTVDDGKIKKVANAVLCALGSLFSKPIKDLLGKLKPLNLL
NLLASCDWTFAGVVETVILAAELFNVFWTPPDVSNFIASIIGDFEMQGPEDLAVELVP
VVMGGIGMVLGFTAEKIGRMLSSAASTLRACKDLGNYALDILKLVMKWFFPKKEEKAE
METLRAIEDAVLDMEAIGNNHLTTLLKDKDSLSAYMKTLDMEEEKARKLSTKSSSPDI
VGTINAILARIAAARSLLHRAKEEMFSRARPVVVMVSGRPGIGKTYLARQLAKSIANS
MSGDQRVGLVPRNGVDHWDAYRGERVVLWDDYGMGNTIKDALTLQELADTCPVTLNCD
RIENKGKMFDSDVIIITTNLVNPAPLDYVNFEACCRRIDFLVYAEAPDIEKVKKDFPG
QPDMWRDHFKADSSHIKLSLAPQGGFDKNGNTPHGKGTMKTLTLHSLTARVMGLVCER
KDEFQLQGDELQVYNFDTNKVSAFRKLAADNKYSFVETMKVGAVLKNVRTLEDLKSAL
KGVKFKECEIVYKGAKYRVASDGCGSVSVSKIKDVASQTANEVHTALLRLRQARARYY
ISCFQDLIYTLIQVAGASFVVHRISKRFSWDRWIKPSESPQEEEQPSSEVATGRWEIE
PKDTDPEGKKGKNKKGRGRKHTAFSSKGLSDEEYDEFKRIREEKNGKYSIEEYLQDRD
RFYEEVAVARATEEDFCEEEVAKIRQRIFRPTKKQRKEERGVLGLVTGSEIRKRRPDD
FQPKGNLWADDTRSVDYNEKLEFEAPPSVWSRIVPLGTGWGFWVSSNLLITTTHVLPK
GVRELFGVDIKQIQIHKSGEFCRFRFPRPIRPDVTGLILEEGAPEGTVCSILIKRPTG
EMIPLAVRMGTHASMKIQGRTVGGQMGMLLTGANAKNMDLGTNPGDCGCPYIFKRGND
IVVAGVHTAAARGGNTVICATQGADGEAVLEGGDDKGTYCGAPILGLGKAPKLSTKTK
FWRSSPDALPPGTYEPAYLGGKDPRVEKGPSLQQVMREQLKPFTEPRGKPPNPSVLDE
AKKTVMNVLEQTINPAKPWSYSQACASLDKTTSSGSPHHLRKNDHWNGESFTGPLADQ
ASKANLMYEQAKHVSPVYTAALKDELVKTDKIYNKIKKRLLWGSDLGTMVRCARAFGG
LMDSMKESCVMLPCRVGMNMNEDGPIIFDKHAKYKYHYDADYSRWDSTQQRCILSAAM
EVMVKFSAEPELAQVVAEDLLAPSQLDVGDFVVSVQEGLPSGVPCTSQWNSIAHWIIT
LSAMAEVSGLSPDVIQAHSCFSFYGDDEIVSTDINLDPAKLTLKLREYGLVPTRPDKT
EGPLVITENLHGLTFLRRHITRDPAGWFGKLDQDSILRQLYWTRGPNHENPYESMVPH
SQRATQLMALLGEASLHGPQFYKKVSKMVINEIKSGGLEFYVPRQEAMFRWMRFSDLS
TWEGDRNLAPDGVNEDGVE"
mat_peptide <1..970
/gene="ORF1"
/product="p48"
mat_peptide 971..2068
/gene="ORF1"
/product="NTPase"
mat_peptide 2069..2590
/gene="ORF1"
/product="p22"
mat_peptide 2591..2989
/gene="ORF1"
/product="VPg"
mat_peptide 2990..3532
/gene="ORF1"
/product="Pro"
mat_peptide 3533..5062
/gene="ORF1"
/product="RdRp"
gene 5046..6713
/gene="ORF2"
CDS 5046..6713
/gene="ORF2"
/note="major capsid protein"
/codon_start=1
/product="VP1"
/protein_id="QPC96811.1"
/translation="MRMASSDAPVSGTDGAAGLVPESQQEVLPLEPVAGVQLAAPVAG
QSNIIDPWIRMNFVQAPAGEFTVSPRNAPGEVLIDLELGPELNPYLNHLARMYNGYVG
GMEVEVVLAGNAFTAGKILFAAVPPSFPTHGISAAQATMLPHVIVDVRQLEPVRLPLP
DVRNVMFHFCQENKEPRMRIVAILYTPLRANGAGDDVFTVSCRVLTRPSPDFDFIFLV
PPSVESKLKQFTLPNLQPNEMTNSRFPTGITQLYTSPNTNLVVQFQNGRCLLDGTLLG
TTPVRAADICSFRGVTSTEVDATDSPRVAGSHRIMVQLREPDGEEFSPTGPNPAPVGT
PDFQAAIFGTLSQRNTGGAGQNSNRAHFAYFYTRNPTFAPGIGTVVFSFDTTDFQNRQ
PTKFSPSGVFDDDSSEPFNQFSLPYYNGSLGAVDAGKLAPPVAPNYPGEQILYFRGNI
PFKGGYGEGEIDSLLPQEWITHFYAEQAPTQGDAALLRYYNPDTGRVLFECKLHREGF
ITINYTGSNALAVPVNGVFRFEGWVNKFYTLTPMGNGNGRRGRRREL"
gene 6713..7435
/gene="ORF3"
CDS 6713..7435
/gene="ORF3"
/note="minor structural protein; small basic protein"
/codon_start=1
/product="VP2"
/protein_id="QPC96812.1"
/translation="MAGAFFAGLASDVLGSGLSSLIGAGANAINQKVEYDYNRHLQSA
SFQHDKDMLSSQVEATKHLQREMMAIKEGMLLKGGFSPTDAARGAVNAPMTQILDWSG
TRYWAPGAMKTTAYSGRFVSQSTHRPIPNVVHKSEGSTHQTGSSTGSISSLSTSSTRV
PSSTSSSSRTRDWVSEQQRLSPFMRGSLQTAYVTPPSSSASSVSSVSTVPHYVLDSWT
PSFNTKHLPLFAHVKKRGQSQV"
ORIGIN
1 ctttggcagc cagaaagcta ccaatgacag ctatagcaca ccccctccca acaaggagga
61 gactagtgtg ctcaccaacg ttaaagttgg ttttaaaaag attctcgggg ccgttcccaa
121 ggcttcgaga cagcatggca acatacaaaa accgccgatc gttgagatcg atggtgtggc
181 catgcgtgta ccctctcccc ccccaaacgg cgaagacgcg gttcactttg tgaaggaaac
241 ggagaccatc aagggattgc cagatttgtc caccgtggaa aacgaatctg aacactcccc
301 atacacagtc ccaccgctga gtgagaggga acacaggcca gcaacagaac ccctgcctgg
361 cactatactt gagatgtggg atggtgagtt ctatcactac tccatatatg tggacaatgg
421 taaggctctt ggtgtgcaca aaccaccagc agcaatcagc ctagcaacga tagatttaac
481 acctatatcg ttgtattgga gaccggtgta cacaccgccg taccttgttc acccagagac
541 actcaaaggg ctggctggtg aaaagtttcc ctacacagct ttcagcaaca actgctacaa
601 cttctgttgc tgggttctgg acctcaatga ctcatggttg aaccggagat ccataaatag
661 gacaactgga ttcttcaaac cctaccaaac ctggaacagg aaacccctcc caactgtgga
721 tgatggtaag atcaagaagg tcgcaaatgc agttctgtgc gccctaggat cacttttctc
781 aaaacccatt aaggacctcc ttgggaagct aaagcccctt aatctcctaa atctgctcgc
841 atcatgtgac tggacctttg ctggtgtagt agaaacagtc attcttgcag cagagctctt
901 caatgtcttt tggactccac ctgatgtctc taacttcatt gcctccataa ttggtgactt
961 tgagatgcaa ggaccagaag accttgctgt ggagcttgtc cccgttgtca tgggaggcat
1021 tggtatggtg ttaggattca cagctgagaa gatagggcgc atgttatcat ctgcagcatc
1081 cactcttaga gcttgtaagg accttggcaa ttacgccctg gacattctaa aactggtcat
1141 gaaatggttc ttccctaaga aggaggagaa ggccgagatg gaaactctaa gagccattga
1201 ggacgctgtt cttgacatgg aggcaattgg caacaaccac ctcacaacat tgctcaaaga
1261 caaggacagc ctaagcgcct acatgaagac cttagacatg gaggaggaaa aggccaggaa
1321 actctcaacc aaatcatcat cacccgacat tgttggcacc atcaatgcga ttcttgcccg
1381 tattgccgct gcaagatcac tcctgcacag agccaaagag gagatgttca gtcgggcgag
1441 gcctgttgtc gtgatggtct ccgggaggcc cgggatcggg aagacttacc tggctagaca
1501 acttgctaag tcaattgcaa acagcatgag tggtgaccag agggtgggac ttgtcccccg
1561 caatggggtt gaccactggg atgcctatag gggtgagaga gtcgtcctat gggatgacta
1621 tggtatggga aacacaatta aagatgccct gactctacag gagttggcag acacctgccc
1681 agtcaccctt aattgtgaca gaatcgagaa caaagggaag atgtttgaca gtgatgtcat
1741 cataattaca accaatcttg tcaaccccgc ccccctcgat tacgtcaact ttgaggcttg
1801 ctgtaggcga attgacttcc ttgtctatgc cgaggcacca gacattgaga aagtcaaaaa
1861 ggatttccct ggacaaccag acatgtggcg tgaccatttc aaagctgatt catcacatat
1921 aaagttgtca ctagccccac agggtggttt cgacaaaaat ggaaacaccc ctcatgggaa
1981 gggcaccatg aaaaccctca cgctgcactc gctcactgca cgtgtgatgg gcttagtgtg
2041 tgagagaaag gatgagttcc aattacaggg ggacgaactg caggtttaca actttgacac
2101 aaacaaagtc tctgcattta gaaagctggc agctgacaac aagtacagtt ttgtggagac
2161 aatgaaagtt ggtgcggtcc tcaagaatgt gcgaactctg gaagacctaa aatctgccct
2221 caaaggagtc aagttcaagg agtgtgaaat agtctacaaa ggggctaagt acagggtcgc
2281 ctcggatggc tgtggcagtg tctcggtctc taagatcaag gatgttgcat cacagacagc
2341 caatgaagtg cacacagcgc tcctgagact gaggcaggcc cgggccagat actacatcag
2401 ctgcttccaa gaccttatct acaccctgat tcaggttgct ggagcctcat ttgtggtgca
2461 taggatctca aagagattct cctgggaccg ttggattaaa cccagtgaga gccctcaaga
2521 ggaagaacaa cccagcagtg aggtggctac agggagatgg gaaattgagc caaaggacac
2581 agaccctgaa ggtaaaaagg gtaaaaacaa gaagggaagg ggaaggaaac acacagcctt
2641 ctctagcaag ggtcttagtg atgaagagta cgatgagttc aagagaatca gagaggagaa
2701 gaacggcaag tactctatag aagaatacct ccaggaccgt gacagatttt atgaggaagt
2761 agcagttgca agggccacgg aagaagactt ctgtgaagaa gaggtggcga agatcaggca
2821 gaggattttc agacccacaa agaagcagag gaaggaggaa cggggcgtcc ttgggctagt
2881 caccggttca gaaatcagga agagaagacc agatgacttc cagcctaaag gtaatttgtg
2941 ggctgatgac accaggagcg tggactacaa cgagaagctg gaatttgaag cccctccaag
3001 tgtgtggtca cgcatcgtgc cccttggcac tggttggggt ttttgggtct cttccaacct
3061 cctcataaca acaacgcacg tcctgccaaa aggagtgaga gagctgttcg gagttgacat
3121 caaacaaatc cagatacaca aatcaggtga gttttgcagg ttcaggtttc caagaccgat
3181 cagaccagat gtcacaggcc tcatccttga agaaggagcc cctgaaggca cggtgtgttc
3241 tatcctcatc aaaagaccga ctggagagat gataccgctc gcagtgagga tgggcaccca
3301 cgcttccatg aaaattcagg gcagaacagt tggtggtcaa atgggcatgt tgctcacagg
3361 ggcaaatgcc aaaaacatgg atttgggcac gaaccctggt gactgtggct gcccgtacat
3421 ttttaaaagg ggcaatgaca ttgtagtagc tggggttcac accgcagctg caaggggtgg
3481 caataccgtg atctgtgcca cgcagggagc tgacggagag gccgtccttg aaggaggaga
3541 tgacaaagga acatactgtg gtgccccaat acttggactt gggaaggccc ccaaactcag
3601 cactaagaca aagttttggc gttcctcacc cgatgcacta cccccgggaa cgtatgaacc
3661 ggcctatcta ggtggaaaag acccaagagt tgagaagggc ccatcactcc agcaggttat
3721 gagagaacaa cttaaaccat tcaccgaacc cagaggaaaa ccgccaaatc ccagcgttct
3781 tgatgaggca aagaaaactg tgatgaatgt gttggagcaa accataaacc ctgccaaacc
3841 ctggtcatat tcccaagcat gcgcttcact tgacaaaacg acttcaagtg gtagcccaca
3901 ccacctgagg aagaatgatc actggaatgg tgagtctttc accggccctt tagccgacca
3961 agcttcaaag gcaaacctaa tgtatgaaca ggcaaaacac gtgagccccg tttacactgc
4021 agccctcaaa gatgaactag tcaagactga caagatttac aataagataa agaagaggtt
4081 gctgtggggt tctgacctgg gcaccatggt caggtgtgcc agagcctttg gtgggttaat
4141 ggacagcatg aaagagagtt gtgtgatgtt gccctgcaga gttggaatga acatgaatga
4201 ggatgggcca atcatttttg acaaacatgc aaaatataaa taccactatg atgcagatta
4261 ctccagatgg gattccacac agcaaagatg catcttgtct gctgccatgg aagtcatggt
4321 aaagttctca gctgaaccgg aattggcaca agtggttgct gaagacttac tcgccccgag
4381 ccaactcgac gtgggcgatt ttgtggtgtc agttcaagaa ggccttcctt caggtgtccc
4441 atgcacctcc cagtggaact ctatagcaca ctggatcatt acccttagtg caatggcaga
4501 agtctctggt ctctccccag atgtgatcca agcccactca tgcttctctt tttacggtga
4561 tgatgagata gttagcacag acattaatct ggacccagca aaattaacct tgaaacttag
4621 ggaatatgga ttggtcccca ccagaccaga caaaactgag ggcccactag tcatcacaga
4681 gaacctccac gggttgacct tcctacgcag gcacatcaca cgagaccctg ctggatggtt
4741 tggtaaatta gatcaggact caatcttaag gcagctctat tggaccagag gacccaacca
4801 tgagaatccc tatgagagca tggttccaca ctcacagcgc gcaacccagc taatggcgct
4861 gttgggtgag gcatcgctac acggtcccca gttttacaag aaagttagca agatggttat
4921 caatgagatc aagagtggtg gtctggaatt ttacgtgccc agacaggagg ccatgttcag
4981 gtggatgaga ttctctgacc tcagcacgtg ggagggcgat cgcaatctgg ctcccgacgg
5041 tgtgaatgag gatggcgtcg agtgacgcgc ccgtttctgg caccgatggt gcggcaggac
5101 tcgtcccaga gagtcaacaa gaagtcttgc ctttagagcc cgtcgcggga gttcagctgg
5161 ctgctcccgt tgcagggcaa agtaatataa ttgacccctg gattagaatg aattttgtgc
5221 aagccccggc cggtgagttc actgtgtccc ctcggaacgc accgggtgag gtacttattg
5281 atttagaatt aggaccagaa ttaaatccct atctcaatca ccttgcaaga atgtataatg
5341 ggtatgtggg aggaatggag gtggaagttg tccttgccgg gaatgcgttc acggcgggta
5401 agatcttgtt tgcagctgtg ccccccagct tcccaaccca tggtatctct gcagcacagg
5461 caactatgct accacatgtg attgtggatg tcaggcagct ggagcctgtc cggctccccc
5521 tccctgacgt caggaatgtg atgttccatt tctgtcaaga gaacaaggag ccgcgtatga
5581 gaattgtggc aatattgtac acccccctcc gtgccaacgg tgcgggtgat gatgttttca
5641 ctgtctcatg tcgtgtgcta acaagaccct caccagattt tgattttatt ttcttggtcc
5701 ccccctctgt agagagtaag ttgaaacagt ttaccctccc aaacctgcag ccaaatgaga
5761 tgaccaattc aagatttcct acaggtatca cacagcttta caccagtcca aacaccaatt
5821 tggttgtcca gttccaaaat ggcaggtgtc tgcttgatgg tacacttctt ggcaccaccc
5881 ctgttagagc tgctgacatc tgcagtttta gaggggttac atcaactgaa gttgatgcaa
5941 ctgacagccc cagggtagca gggtcacata gaattatggt gcagcttagg gagccagatg
6001 gagaggagtt ttcacccaca ggtcccaacc ctgcccctgt tggcacccca gactttcaag
6061 cagccatatt tggcactctc agtcaaagaa acactggcgg agctgggcag aattccaaca
6121 gagcccactt cgcatacttc tacacaagaa accccacatt tgcaccaggc atagggactg
6181 ttgtattttc ttttgacact actgatttcc aaaatcgtca acctaccaaa ttttctcctt
6241 ctggtgtgtt tgatgatgat tcttctgaac cttttaatca gttctccctg ccatattata
6301 atggatcact cggtgcagtg gacgctggaa aactggctcc gcctgtggca cccaattatc
6361 caggtgagca gattctttat tttagaggga atataccttt caaaggtggg tatggagaag
6421 gtgaaattga cagtttactt ccccaggaat ggatcaccca cttctatgca gagcaggccc
6481 ccacacaagg tgacgcagcc ctgctgcgct actacaaccc tgacactggt agagtcctct
6541 ttgagtgcaa actccatcgc gaaggattca ttacaatcaa ttacacggga tccaatgctc
6601 ttgctgtacc agtcaatgga gtcttcaggt ttgagggctg ggttaacaaa ttctacacac
6661 tgacccccat gggaaatggc aatggtcgta ggggtagaag aagggagtta taatggctgg
6721 agctttcttt gcaggtcttg cttctgatgt tcttggcagc ggtttgtctt ctcttattgg
6781 tgccggtgcc aatgctataa accaaaaagt tgaatatgat tacaataggc atttgcaatc
6841 agcttctttc caacatgaca aggacatgct tagctcacag gtggaagcca caaagcacct
6901 gcagagggaa atgatggcca tcaaggaagg catgctgctt aagggcgggt tctcccccac
6961 tgatgcagca aggggggctg tcaacgcccc tatgacacaa atcttggatt ggagtggcac
7021 cagatattgg gccccaggtg caatgaaaac tacggcctat tcaggccgtt ttgtcagcca
7081 atccacccac aggcccattc ccaatgttgt gcacaagagt gagggatcca cacaccaaac
7141 tgggtcatcc accggatcta tctcttctct ttccacatca tccacccgtg ttccatcatc
7201 tacatcctca tctagtagaa caagagactg ggtgtctgaa caacaaagac tcagcccttt
7261 catgagaggc tctcttcaaa ctgcatatgt gactcctccc tcaagctctg cctcttcagt
7321 aagctctgtt tctacagtcc cacactatgt tttagattca tggactcctt cttttaacac
7381 taagcattta cccctatttg cccatgttaa gaaaagggga caatctcaag tttaatctac
7441 cactcatggt ttgattgatt tgttttgtaa ttagtgaaat gttgattctt ttctaattcg
7501 gcattt
//