Typing tool
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Typing tool
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Complete norovirus genomes
| MW261795 | GIX.1 | |
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| GII.P15 |
ORF1: 1..5065
ORF2: 5046..6713
ORF3: 6713..7444
LOCUS MW261795 7515 bp RNA linear VRL 13-APR-2022
DEFINITION Norovirus GIX isolate DS383 nonstructural polyprotein (ORF1) gene,
partial cds; and VP1 (ORF2) and VP2 (ORF3) genes, complete cds.
ACCESSION MW261795
VERSION MW261795.1
KEYWORDS .
SOURCE Norovirus GIX
ORGANISM Norovirus GIX
Viruses; Riboviria; Orthornavirae; Pisuviricota; Pisoniviricetes;
Picornavirales; Caliciviridae; Norovirus; Norwalk virus.
REFERENCE 1 (bases 1 to 7515)
AUTHORS Tohma,K., Lepore,C.J., Martinez,M., Degiuseppe,J.I., Khamrin,P.,
Saito,M., Mayta,H., Nwaba,A.U.A., Ford-Siltz,L.A., Green,K.Y.,
Galeano,M.E., Zimic,M., Stupka,J.A., Gilman,R.H., Maneekarn,N.,
Ushijima,H. and Parra,G.I.
TITLE Genome-wide analyses of human noroviruses provide insights on
evolutionary dynamics and evidence of coexisting viral populations
evolving under recombination constraints
JOURNAL PLoS Pathog 17 (7), e1009744 (2021)
PUBMED 34255807
REMARK Publication Status: Online-Only
REFERENCE 2 (bases 1 to 7515)
AUTHORS Tohma,K., Lepore,C.J., Martinez,M., Degiuseppe,J.I., Khamrin,P.,
Saito,M., Mayta,H., Nwaba,A., Ford-Siltz,L.A., Galeano,M.E.,
Zimic,M., Stupka,J.A., Gilman,R.H., Maneekarn,N., Ushijima,H.,
Green,K.Y. and Parra,G.I.
TITLE Direct Submission
JOURNAL Submitted (16-NOV-2020) CBER/OVRR/DVP/LHV, U.S. Food and Drug
Administration, 10903 New Hampshire Avenue, Silver Spring, MD
20993, USA
COMMENT ##Assembly-Data-START##
Assembly Method :: High-performance Integrated Virtual
Environment (HIVE) v. 2
Sequencing Technology :: Illumina
##Assembly-Data-END##
FEATURES Location/Qualifiers
source 1..7515
/organism="Norovirus GIX"
/mol_type="genomic RNA"
/isolate="DS383"
/isolation_source="feces"
/host="Homo sapiens"
/db_xref="taxon:2594528"
/country="Saudi Arabia"
/collection_date="1990"
/note="genotype: GIX.1 [GII.P15]"
gene <1..5065
/gene="ORF1"
CDS <1..5065
/gene="ORF1"
/codon_start=2
/product="nonstructural polyprotein"
/protein_id="QPC96798.1"
/translation="LGSQKATNDSYSTPPPNKEEASVLTNVKVGFKKILGAVPKASRQ
HGNTQKPPIVEIDGVAMRVPSPPPNGEDAVHFVKETETIKGLPDLSTVENESEHSPYT
VPPLSEREHRPATEPLPGTILEMWDGEFYHYSIYVDNGKALGVHKPPAAISLATIDLT
PISLYWRPVYTPPYLVHPETLKGLAGEKFPYTAFSNNCYNFCCWVLDLSDSWLNRRSI
NRTTGFFKPYQTWNRKPLPTVDDGKIKKVANAVLCALGSLFSKPIKDLLGKLKPLNLL
NLLASCDWTFAGVVETVILAAELFNVFWTPPDVSNFIASIIGDFEMQGPEDLAVELVP
VVMGGIGMVLGFTAEKIGRMLSSAASTLRACKDLGNYALDILKLVMKWFFPKKEEKAE
METLRAIEDAVLDMEAIGNNHLTTLLKDKDSLNAYMKTLDMEEEKARKLSTKSSSPDI
VGTINAILARIAAARSLLHKAKEEMFSRARPVVIMVSGRPGIGKTYLARQLAKSIANS
MSGDQRVGLVPRNGVDHWDAYRGERVVLWDDYGMGNTIKDALTLQELADTCPVTLNCD
RIENKGKMFDSDVIIITTNLINPAPLDYVNFEACCRRIDFLVYAEAPDIEKVKKDFPG
QPDMWRDHFKADSSHIKLSLAPQGGFDKNGNTPHGKGTMRTLTLHSLTARVMGLVCER
KDEFQLQGDELQVYNFDTNKVSAFRKLAADNKYSFVETMKVGAVLKNVRTLEDLKSAL
KGVKFKECEIIYKGAKYRVASDGCGSVSVSKIKDVATQTANEVHTALLRLRQARARYY
ISCFQDLIYTLIQVAGASFVVHRISKRFSWDRWIKPSESPQEEEQPSSEVATGRWEIE
PKDTDPEGKKGKNKKGRGRKHTAFSSKGLSDEEYDEFKRIREEKNGKYSIEEYLQDRD
RFYEEVAVARATEEDFCEEEVAKIRQRIFRPTKKQRKEERGVLGLVTGSEIRKRRPDD
FQPKGNLWADDTRSVNYNEKLEFEAPPSVWSRIVPLGTGWGFWVSSNLLITTTHVLPK
GVRELFGVDIKQIQIHKSGEFCRFRFPRPIRPDVTGLILEEGAPEGTVCSILIKRPTG
EMIPLAVRMGTHASMKIQGRTVGGQMGMLLTGANAKNMDLGTNPGDCGCPYIFKRGND
IVVAGVHTAAARGGNTVICATQGADGEAVLEGGEDKGTYCGAPILGLGKAPNLSTKTK
FWRSSPDALPPGTYEPAYLGGKDPRVEKGPSLQQVMREQLKPFTEPRGKPPNPNVLDE
AKKTVMNVLEQTINPAKPWSYSQACASLDKTTSSGSPHHLRKNDHWNGESFTGPLADQ
ASKANLMYEQAKHVSPVYTAALKDELVKTDKIYKKIKKRLLWGSDLGTMVRCARAFGG
LMDSMKESCVMLPCRVGMNMNEDGPIIFDKHAKYKYHYDADYSRWDSTQQRCILSAAM
EVMVKFSAEPELAQVVAEDLLAPSQLDVGDFVVSVQEGLPSGVPCTSQWNSIAHWIIT
LSAMAEVSGLSPDVIQAHSCFSFYGDDEIVSTDINLDPAKLTLKLREYGLVPTRPDKT
EGPLVITENLHGLTFLRRHITRDPAGWFGKLDQDSILRQLYWTRGPNHENPYESMVPH
SQRATQLMALLGEASLHGPQFYKKVSKMVINEIKSGGLEFYVPRQEAMFRWMRFSDLS
TWEGDRNLAPDGVNEDGVE"
mat_peptide <1..970
/gene="ORF1"
/product="p48"
mat_peptide 971..2068
/gene="ORF1"
/product="NTPase"
mat_peptide 2069..2590
/gene="ORF1"
/product="p22"
mat_peptide 2591..2989
/gene="ORF1"
/product="VPg"
mat_peptide 2990..3532
/gene="ORF1"
/product="Pro"
mat_peptide 3533..5062
/gene="ORF1"
/product="RdRp"
gene 5046..6713
/gene="ORF2"
CDS 5046..6713
/gene="ORF2"
/note="major capsid protein"
/codon_start=1
/product="VP1"
/protein_id="QPC96799.1"
/translation="MRMASSDAPVSGTDGAAGLVPESQQEVLPLEPVAGVQLAAPVAG
QSNIIDPWIRMNFVQAPAGEFTVSPRNAPGEVLIDLELGPELNPYLNHLARMYNGYVG
GMEVEVVLAGNAFTAGKILFAAVPPSFPTHGISAAQATMLPHVIVDVRQLEPVRLPLP
DVRNVMFHFCQENKEPRMRIVAILYTPLRANGAGDDVFTVSCRVLTRPSPDFDFIFLV
PPSVESKLKQFTLPNLQPNEMTNSRFPTGITQLYTSPNTNLVVQFQNGRCLLDGTLLG
TTPVRAADICSFRGVTSTEVDATDSPRVAGSHRIMVQLKEPDGEEFSPTGPNPAPVGT
PDFQAAIFGTLSQRNTGGAGQNSNRAHFAYFYTRNPTFAPGIGTVVFSFDTTDFQNRQ
PTKFSPSGVFDDDSSEPFNQFSLPYYNGSLGAVDAGKLAPPVAPNYPGEQILYFRGNI
PFKGGYGEGEIDSLLPQEWITHFYAEQAPTQGDAALLRYYNPDTGRVLFECKLHREGF
ITINYTGSNALAVPVNGVFRFEGWVNKFYTLTPMGNGNGRRGRRREL"
gene 6713..7444
/gene="ORF3"
CDS 6713..7444
/gene="ORF3"
/note="minor structural protein; small basic protein"
/codon_start=1
/product="VP2"
/protein_id="QPC96800.1"
/translation="MAGAFFAGLASDVLGSGLSSLIGAGANAINQKVEYDYNRHLQSA
SFQHDKDMLSSQVEATKHLQREMMAIKEGMLLKGGFSPTDAARGAVNAPMTQILDWSG
TRYWAPGAMKTTAYSGRFVSQSTHRPIPNVVHKSEGSTHQTGSSTGSVSSLSTSSTRV
PSSTSSSSSTSRTRDWVSEQQRLSPFMRGSLQTAFVTPPSSSASSVSSVSTVPHYVLD
SWTPSFNTKHLPLFAHVKKRGQSQV"
ORIGIN
1 ccttggcagc cagaaagcta ccaatgacag ctatagcaca ccccctccca acaaggagga
61 ggctagtgtg ctcaccaacg ttaaagttgg ttttaaaaag atcctcgggg ccgttcctaa
121 ggcttcgaga cagcatggca acacgcaaaa accgccgatc gtcgagatcg atggtgtggc
181 catgcgtgtg ccctctcccc ccccaaacgg tgaggacgca gttcactttg tgaaggaaac
241 ggagaccatc aagggattgc cagatttgtc caccgtggaa aacgaatctg aacactcccc
301 atacacagtc ccaccgttga gtgagaggga acacaggcca gcaacagagc ccttgcctgg
361 cactatactt gagatgtggg atggtgagtt ctaccactac tccatatatg tggacaacgg
421 caaggctctt ggtgtgcaca aaccaccggc agcaatcagc ctagcaacga tagatttaac
481 acctatatcg ttgtattgga gaccggtgta cacaccgccg taccttgttc acccagagac
541 acttaagggg ctggctggtg aaaagtttcc ctacacagct ttcagcaata actgctacaa
601 cttttgttgc tgggttctgg acctcagtga ctcatggttg aaccggagat ccataaatag
661 gacaactgga ttcttcaaac cctaccaaac ctggaacagg aaacccctcc caactgtgga
721 tgatggtaag atcaagaagg tcgcaaacgc agttctgtgc gccctaggat cacttttctc
781 aaaacccatt aaggacctcc ttgggaagtt aaagcccctc aacctcctaa atctgctcgc
841 gtcatgcgac tggacctttg ctggtgtagt ggaaacagtc attcttgcag cagagctctt
901 taacgtcttt tggactccac ctgatgtctc caacttcatt gcctccataa ttggtgactt
961 tgagatgcaa ggaccagaag accttgctgt ggagcttgtt cccgttgtca tgggaggcat
1021 tggtatggtg ttaggattta cagctgagaa gatagggcgc atgttatcat ctgcagcatc
1081 cactcttaga gcttgtaagg accttggcaa ctacgccctg gacatcctaa aactggtcat
1141 gaaatggttc ttccctaaga aggaggagaa ggccgagatg gagaccctaa gagccattga
1201 ggatgccgtc cttgacatgg aggcaattgg caacaaccac cttacaacat tgcttaaaga
1261 caaggacagc ctaaacgcct atatgaagac cttagacatg gaggaggaaa aggccaggaa
1321 actctcaacc aaatcatcat cacccgacat tgttggcacc atcaatgcga tccttgctcg
1381 cattgccgct gcaagatcac tcctgcacaa agccaaagag gaaatgttca gtcgagcgag
1441 gcctgttgtc ataatggttt ccgggagacc cgggatcggg aagacatacc tggctagaca
1501 acttgctaag tcaattgcaa acagcatgag tggtgatcag agggtaggac ttgtcccccg
1561 caatggggtt gaccactggg atgcctatag gggtgagaga gtcgtcctat gggatgacta
1621 tggcatggga aacacaatta aagatgccct gactttacag gagttagcag acacctgccc
1681 agttaccctc aactgtgaca gaatcgagaa caaggggaag atgtttgaca gtgatgtcat
1741 cataattaca accaatctta tcaatcctgc tccccttgat tatgtcaact ttgaggcttg
1801 ctgcaggcga attgacttcc ttgtctatgc cgaggcacca gacattgaga aagtcaaaaa
1861 ggacttccct ggacaaccag acatgtggcg tgaccatttc aaagctgatt catctcacat
1921 aaagttgtca ctagccccac agggtggttt tgacaaaaat ggaaacaccc ctcatgggaa
1981 gggcaccatg agaaccctca cgctgcactc actcactgca cgtgtgatgg gcttagtgtg
2041 tgagagaaag gatgagttcc aattacaggg ggacgaactg caggtttaca actttgacac
2101 aaacaaggtc tctgcattca gaaagctggc agctgacaac aagtacagtt tcgtggagac
2161 aatgaaagtt ggtgcggtcc tcaagaatgt gagaaccctg gaagacctaa aatctgccct
2221 caaaggagtc aagttcaaag agtgtgaaat aatttacaaa ggggctaagt acagggtcgc
2281 ctcggacggc tgtggcagtg tctcggtctc taagatcaag gatgttgcga cacagacagc
2341 caatgaagtg cacacagcgc tactgagact gaggcaagcc cgagccagat actacatcag
2401 ctgcttccaa gaccttatct acaccctgat tcaggttgcc ggagcctcat tcgtggtgca
2461 caggatctca aagagattct cctgggaccg ttggattaaa cccagtgaga gccctcaaga
2521 ggaagaacaa cctagcagtg aggtggccac aggaaggtgg gaaattgagc caaaggacac
2581 agaccctgaa ggtaaaaagg gtaaaaacaa gaaggggagg ggaaggaaac acacagcttt
2641 ctctagcaag ggccttagtg atgaagagta cgatgagttc aagagaatca gagaggagaa
2701 gaacggcaag tactctatag aagaatacct ccaggaccgt gacagatttt atgaggaagt
2761 ggcagttgca agagccacgg aagaggactt ctgtgaggaa gaagtggcga agatcaggca
2821 gaggattttc agacccacaa agaagcagag gaaggaggaa cggggcgtcc ttgggctagt
2881 caccggttca gaaattagga agagaagacc agatgacttc cagcctaaag gtaatttgtg
2941 ggctgatgac accaggagcg tgaactacaa cgagaagctg gaatttgaag cccctccgag
3001 tgtgtggtca cgcatcgtac cccttggcac tggttggggt ttttgggtct cctctaacct
3061 cctcataaca acaacgcacg tcctgccaaa aggagtgaga gagctgttcg gagttgacat
3121 caaacaaatt cagatacata aatcaggtga gttttgcagg ttcaggtttc caagaccgat
3181 cagaccagat gtcacaggcc tcatccttga agaaggtgcc cctgaaggca cggtgtgttc
3241 tattctcatc aagaggccga ctggagagat gataccgctc gcagtgagga tgggcaccca
3301 cgcttctatg aaaatccagg gcagaacagt tggtggtcaa atgggcatgt tgctcacagg
3361 ggcaaatgcc aaaaacatgg atttgggcac gaaccctggt gactgtggct gcccgtacat
3421 ctttaaaagg ggcaatgaca ttgtagtagc tggggttcac actgcagctg caagaggtgg
3481 caatactgtg atctgtgcca cgcagggagc tgacggagaa gctgtccttg aaggaggaga
3541 ggacaaagga acatactgtg gtgccccaat acttggactt gggaaggccc ctaatttaag
3601 caccaagaca aagttttggc gttcctcgcc tgatgcacta cctccgggaa cgtatgaacc
3661 agcctatcta ggtggaaaag acccaagagt tgagaagggc ccatctctcc agcaggttat
3721 gagagaacaa cttaaaccat tcaccgaacc cagaggaaaa ccgccaaatc ccaacgttct
3781 tgacgaggcg aagaaaactg tgatgaacgt gttggagcaa accataaacc ctgccaagcc
3841 ctggtcatat tcccaagcat gcgcttcact tgacaaaacg acttcaagtg gtagcccaca
3901 ccacctgagg aagaacgacc actggaatgg tgagtctttc actggccctt tggcagacca
3961 agcttcaaag gcaaacctga tgtatgagca ggcaaaacac gtgagccccg tttacactgc
4021 agccctcaaa gatgaactag tcaagactga caagatttac aagaagataa agaagaggtt
4081 actgtggggt tctgacctgg gcaccatggt caggtgtgcc agagcctttg gtgggttaat
4141 ggacagcatg aaagagagtt gtgtgatgtt gccctgcaga gttggaatga acatgaatga
4201 agatgggcca atcatttttg acaaacatgc aaaatataaa taccactatg atgcagatta
4261 ctccagatgg gattccacac agcaaagatg catcttatct gctgccatgg aagttatggt
4321 aaagttctca gctgaaccgg aattggcaca agtggttgct gaagacttac tcgccccgag
4381 ccaactcgac gtgggcgatt ttgtggtgtc agttcaagaa ggccttccct caggtgtccc
4441 atgtacctcc caatggaact ctatagcaca ctggatcatt acccttagtg caatggcaga
4501 agtttctggt ctctccccag atgtgatcca agcccattca tgcttttctt tttacggtga
4561 tgatgagata gttagcacag acatcaatct ggacccagca aaattaacct taaaacttag
4621 ggaatatgga ctggtcccca ccagaccaga caaaactgag ggcccactag tcatcactga
4681 gaacctccac gggttgacct tcctacgcag gcacattaca cgagaccctg ctggatggtt
4741 tggtaaatta gatcaggatt caatcttaag gcagctttac tggaccagag gacccaatca
4801 tgagaatccc tacgagagca tggttccaca ctcacagcgc gcaacccagc taatggcgct
4861 gttgggtgag gcatcgctgc acggtcccca gttttacaag aaagttagca agatggttat
4921 caatgagatc aagagtggcg gtctagaatt ttacgtgccc agacaggagg ccatgttcag
4981 atggatgaga ttctctgacc tcagcacgtg ggagggcgat cgcaatctgg ctcccgacgg
5041 tgtgaatgag gatggcgtcg agtgacgcgc ccgtttctgg caccgatggt gcggcaggac
5101 tcgtcccaga gagtcaacaa gaagtcttgc ctttagagcc cgtcgcggga gttcagctgg
5161 ctgctcccgt tgcagggcaa agtaacataa ttgacccctg gattagaatg aattttgtgc
5221 aagccccggc cggtgagttc actgtgtccc ctcggaacgc accgggtgag gtacttattg
5281 atttagaatt aggaccagaa ttaaatccct atctcaatca ccttgcaaga atgtataatg
5341 ggtatgttgg aggaatggag gtggaagttg tccttgccgg gaatgcgttc acggcgggta
5401 agatcctgtt tgcagctgtg ccccccagct tcccaaccca tggcatctct gcagcacagg
5461 caactatgct accacatgtg attgtggatg tcaggcagct ggagcctgtc cggctccccc
5521 tccctgacgt caggaatgtg atgttccatt tttgtcaaga gaataaagaa ccgcgtatga
5581 gaattgtggc aatattgtac acccccctcc gtgctaacgg tgcgggtgat gatgttttca
5641 ctgtctcatg tcgtgtgcta acgaggcctt caccagattt tgattttatt ttcttggtcc
5701 ccccctctgt agagagtaag ttgaaacagt ttaccctccc aaacctacag ccaaatgaga
5761 tgaccaattc aagatttccc acaggtatca cacagcttta caccagtcca aacaccaatt
5821 tggtcgtcca gttccagaat ggcaggtgtc tgcttgatgg cacacttctt ggcaccaccc
5881 ctgtcagagc tgctgacatc tgcagtttta gaggggttac atcaaccgaa gttgatgcaa
5941 ctgacagccc cagggtggca gggtcacata gaattatggt gcagcttaag gagccagatg
6001 gagaggagtt ttcacccaca ggtcccaacc ctgcccctgt tggcacccca gactttcaag
6061 cagccatatt tggcactctc agtcaaagaa acactggcgg agctgggcag aattccaaca
6121 gagcccactt cgcatacttt tacacaagaa accctacatt tgcaccaggc atagggactg
6181 ttgtattttc ttttgatacc actgatttcc aaaatcgtca acctactaaa ttttctcctt
6241 ctggtgtgtt tgatgatgat tcttctgaac cttttaatca gttctccctg ccatattaca
6301 atggatcact cggtgcagtg gacgctggaa aactggctcc gcctgtggca cccaattatc
6361 caggtgagca gattctttat tttagaggga atataccttt caaaggtggg tatggagagg
6421 gtgaaattga cagcttgctt ccccaggaat ggattactca cttttatgca gagcaggccc
6481 ccacacaagg tgacgcagcc ctgctgcgct actacaaccc tgacactggt agagtcctct
6541 ttgagtgcaa actccaccgc gagggattca tcacaatcaa ttacacggga tccaatgctc
6601 ttgctgtacc agtcaatgga gtcttcaggt ttgagggctg ggttaacaaa ttctacacac
6661 tgacccccat gggaaatggc aatggccgca ggggtagaag aagggagtta taatggctgg
6721 agctttcttc gcaggtcttg cttctgatgt tcttggcagc ggtttgtctt ctcttattgg
6781 tgccggtgcc aatgctataa atcaaaaagt tgagtatgat tacaataggc atttgcaatc
6841 agcatctttc caacatgaca aggacatgct tagctcacag gtggaagcca caaagcatct
6901 gcaaagggaa atgatggcca tcaaggaagg catgctgctt aagggcgggt tttcccccac
6961 tgatgcagca aggggggctg tcaacgcccc tatgacacaa atcttggatt ggagtggcac
7021 cagatattgg gccccaggcg caatgaaaac tacggcctat tcaggccgtt ttgtcagcca
7081 atccactcac aggcctatcc ccaatgttgt gcataagagt gagggatcca cacaccaaac
7141 tgggtcatct accggatctg tctcttctct ttccacatca tccacccgtg ttccatcatc
7201 tacatcctca tctagtagta cttctagaac aagagactgg gtgtcagaac aacaaagact
7261 cagccctttc atgagaggct ctcttcaaac tgcatttgtg actcctcctt caagctctgc
7321 ctcttcagta agctctgttt ctacagtccc acactatgtt ttagattcat ggactccttc
7381 ttttaacact aagcatttac cactgtttgc ccatgttaag aaaaggggac aatctcaagt
7441 ttaatctacc actcatggtc tgattgattt gttttgtaat tagtgaaatg ttgattcttt
7501 tctaattcgg cattt
//