Typing tool
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Typing tool
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Complete norovirus genomes
| MW045406 | GII.4 | |
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| GII.P31 |
ORF1: 1..3723
ORF2: 3704..5326
ORF3: 5326..5643
LOCUS MW045406 5643 bp RNA linear VRL 29-DEC-2020
DEFINITION Norovirus GII isolate 2048 nonstructural polyprotein (ORF1) gene,
partial cds; VP1 (ORF2) gene, complete cds; and VP2 (ORF3) gene,
partial cds.
ACCESSION MW045406
VERSION MW045406.1
KEYWORDS .
SOURCE Norovirus GII
ORGANISM Norovirus GII
Viruses; Riboviria; Orthornavirae; Pisuviricota; Pisoniviricetes;
Picornavirales; Caliciviridae; Norovirus; Norwalk virus.
REFERENCE 1 (bases 1 to 5643)
AUTHORS Makhaola,K., Moyo,S. and Kebaabetswe,L.P.
TITLE Next Generation Sequencing of Near-Full Length Genome of Norovirus
GII.4 from Botswana
JOURNAL Unpublished
REFERENCE 2 (bases 1 to 5643)
AUTHORS Makhaola,K., Moyo,S. and Kebaabetswe,L.P.
TITLE Direct Submission
JOURNAL Submitted (29-SEP-2020) Biosciences and Biotechnology, Botswana
International University of Science and Technology, Khurumela,
Palapye 00, Botswana
COMMENT ##Assembly-Data-START##
Assembly Method :: Genome Detective v. 1.126
Sequencing Technology :: Oxford Nanopore(MinION)
##Assembly-Data-END##
FEATURES Location/Qualifiers
source 1..5643
/organism="Norovirus GII"
/mol_type="genomic RNA"
/isolate="2048"
/isolation_source="stool"
/host="Homo sapiens"
/db_xref="taxon:122929"
/country="Botswana: Molepolole"
/collection_date="19-Oct-2017"
/note="genotype: GII.4 Sydney[GII.P31]"
gene <1..3723
/gene="ORF1"
CDS <1..3723
/gene="ORF1"
/codon_start=1
/product="nonstructural polyprotein"
/protein_id="QOD59275.1"
/translation="TINALLARIAAARSLVHRAKEELSSRPRPVVVMISGKPGIGKTH
LARELARKIAASLTGDQRVGLIPRNGVDHWDAYKGERVVLWDDYGMSNPIHDALRLQE
LADTCPLTLNCDRIENKGKVFDSDAIIITTNLANPAPLDYVNFEACSRRIDFLVYAEA
PEVEKAKRDFPGQPDMWKNAFSPDFSHIKLALAPQGGFDKNGNTPHGKGVMKTLTTGS
LIARASGLLHERLDEYELQGPVLTTFNFDRNKILAFRQLAAENKYGLMDTMRVGKQLK
DVKTMPDLKQALKNVAIKKCQIVYNGSTYTLEADGKGSVKVDKVQSATVQTNNELAGA
LHHLRCARIRYYVKCVQEALYSIIQIAGAAFVTTRIAKRMNIQNLWSKPQVEDTEETA
SKDGCPKPKDDEEFVVSSDDIKTEGKKGKNKSGRGKKHTAFSSKGLSDEEYDEYKRIR
DERNGKYSIEEYLQDRDKYYEEVAIARATEEDFCEEEEAKIRQRIFRPTRKQRKEERA
SLGLVTGTEIRKRNPEDFKPKGKLWADDDRSVDYNEKLNFEAPPSIWSRIVNFGSGWG
FWVSPSLFITSTHVIPQGAQEFFGVPIKQIQIHKSGEFCRLRFPKPIRTDVTGMILEE
GAPEGTVATLLIKRPTGELMPLAARMGTQATMKIQGRTVGGQMGMLLTGSNAKSMDLG
TTPGDCGCPYIYKRGNDYIVIGVHTAAARGGNTVICATQGGEGEATLEGGDNKGTYLP
VALSSALLGCLTSTKTKFWRSSTTPLPPGTYEPAYLGGKDPRVKGGPSLQQVMRDQLK
PFTEPRGKPPRPNVLEAAKKTIINVLEQTIDPPQKWSFAQACASLDKTTSSGHPHHMR
KNDCWNGESFTGKLADQASKANLMFEEGKNMTPVYTGALKDELVKTDKIYGKIKKRLL
WGSDLATMIRCARAFGGLMDELKAHCVTLPVRVGMNMNEDGPIIFEKHSRYKYHYDAD
YSRWDSTQQRDVLAAALEIMVKFSPEPHLAQIVAEDLLSPSVMDVGDFQISISEGLPS
GVPCTSQWNSIAHWLLTLCALSEVTDLSPDIIQANSLFSFYGDDEIVSTDIKLDPEKL
TAKLKEYGLKPTRPDKTEGPLVISEDLDGLTFLRRTVTRDPAGWFGKLEQSSILRQMY
WTRGPNHEDPSETMIPHSQRPIQLMSLLGEAALHGPAFYSKISKLVIAELKEGGMDFY
VPRQEPMFRWMRFSDLSTWEGDRNLAPSFVNEDGVE"
mat_peptide <1..711
/gene="ORF1"
/product="NTPase"
mat_peptide 712..1248
/gene="ORF1"
/product="p22"
mat_peptide 1249..1647
/gene="ORF1"
/product="VPg"
mat_peptide 1648..2190
/gene="ORF1"
/product="Pro"
mat_peptide 2191..3720
/gene="ORF1"
/product="RdRp"
gene 3704..5326
/gene="ORF2"
CDS 3704..5326
/gene="ORF2"
/note="major capsid protein"
/codon_start=1
/product="VP1"
/protein_id="QOD59276.1"
/translation="MKMASSDANPSDGSAANLVPEVNNEVMALEPVVGAAIAAPVAGQ
QNVIDPWIRNNFVQAPGGEFTVSPRNAPGEILWSAPLGPGLNPYLSHLARMYNGYAGG
FEVQVILAGNAFTAGKVIFAAVPPNFPTEGLSPSQVTMFPHIVVDVRQLEPVLIPLPD
VRNNFYHYNQSNDPTIKLIAMLYTPLRANNAGDDVFTVSCRVLTRPSPDFDFIFLVPP
TVESRTKQFSVPILTVEEMTNSRFPIPLEKLFTGPSSAFVVQPQNGRCTTDGVLLGTT
QLSPVNICTFRGDVTHITGSRNYTMNLASQNWNNYDPTEEIPAPLGTPDFVGKIQGML
TQTTRTDGSTRGHKATVYTGSADFAPKLGRIQFQTDTDRDFEVHQNTKFTPVGVIQDG
GTTHRNEPQQWVLPSYSGRDTPNVHLAPAVAPTFPGEQLLFFRSTMPGCSGYPNMNLD
CLLPQEWVQYFYQEAAPAQSDVALLRFVNPDTGRVLFECKLHKSGYVTVAHTGQHDLV
IPPNGYFRFDSWVNQFYTLAPMGNGTGRRRAV"
gene 5326..>5643
/gene="ORF3"
CDS 5326..>5643
/gene="ORF3"
/note="minor structural protein; small basic protein"
/codon_start=1
/product="VP2"
/protein_id="QOD59277.1"
/translation="MAGAFFAGLASDVLGSGLGSLINAGAGAINQKVEFENNRKLQQA
SFQFSSNLQQASFQHDKEMLQAQIEATKQLQQEMMKVKQAVLLEGGFSETDAARGAIN
APMT"
ORIGIN
1 acaatcaacg ctcttctggc gagaatcgct gctgcacgtt ctctagtgca tcgggcgaaa
61 gaagagctct ccagcaggcc gagacctgtt gttgtgatga tatcgggaaa accagggata
121 gggaaaaccc accttgccag ggagttggcc aggaagatcg cagcctccct cacaggggac
181 cagcgtgtgg gcctgatccc acgcaatggc gttgaccact gggacgcata caagggtgaa
241 agagttgtcc tatgggacga ctatgggatg agcaacccca tacacgatgc cctcaggttg
301 caggaacttg ctgacacttg ccccctcacg ctaaattgtg acaggattga gaacaaagga
361 aaagtctttg atagtgatgc cataattatc accaccaatc tggccaaccc agcaccactg
421 gattatgtca attttgaagc gtgctcgagg cgcattgatt tcctcgtgta cgcggaggct
481 cctgaggtgg agaaggcaaa acgcgacttc ccaggccaac ctgacatgtg gaagaacgct
541 ttcagtcctg acttctcaca cataaaactg gcattggctc cacagggtgg ttttgacaag
601 aacggcaata ccccgcatgg aaaaggtgtt atgaagactc tcaccactgg ctccctcatt
661 gcccgagcat caggattact ccatgagaga ctagatgaat atgaattaca aggcccagtc
721 ctcactacct tcaactttga ccgcaacaag atacttgcat ttagacagct tgctgctgaa
781 aacaagtatg ggttgatgga cacaatgaga gttggaaaac agcttaagga tgtcaagacc
841 atgccagacc ttaaacaagc actcaagaat gtcgcgatca agaagtgcca gatagtgtat
901 aatggtagca cctacacgct tgaggccgat ggcaagggta gtgtgaaggt tgacaaagtg
961 cagagtgcca ccgtgcaaac taacaatgaa ctagccggcg ccctgcacca cctgaggtgc
1021 gccagaatca ggtactatgt caagtgtgtc caggaggcat tgtattccat catccaaatc
1081 gctggggccg cgtttgtcac cacgcgcatc gccaagcgca tgaacataca aaacctctgg
1141 tccaagccac aggtggaaga cacagaagag acggccagca aagatggttg cccaaaaccc
1201 aaagatgatg aagagttcgt cgtttcatcc gacgacatca agactgaggg caagaaaggg
1261 aagaacaagt ccggccgtgg caagaagcac acagccttct caagcaaagg gctcagtgat
1321 gaggagtacg atgagtacaa gagaatcaga gatgaaagga atggtaagta ctccatagaa
1381 gagtaccttc aggacagaga caagtactat gaggaggtgg ccattgccag ggcaactgaa
1441 gaggacttct gtgaagaaga agaggccaaa atccggcaga gaatttttag accaacaagg
1501 aaacaacgta aagaagagag ggcctcttta ggcttggtca caggcacaga gatcaggaag
1561 agaaacccag aagacttcaa acccaaggga aagctgtggg ctgatgatga cagaagtgtt
1621 gactacaacg agaaactcaa ctttgaggcc ccaccaagca tctggtcgcg gatagtcaac
1681 tttggttcag gttggggatt ttgggtctcc cccagcttat tcattacatc aacccatgtc
1741 ataccccaag gcgcccagga gttctttggg gtgcccatca agcagatcca gatccacaaa
1801 tcgggagagt tttgccgcct aagattccca aaaccaatta ggactgatgt gacaggcatg
1861 atactggaag agggggctcc agaaggaact gtggccacac tgctcatcaa gagaccaact
1921 ggtgagctca tgccactagc ggctagaatg ggcacccagg caactatgaa gatccaaggc
1981 cgcacagttg gtggtcaaat gggcatgcta ttgacagggt ccaacgctaa gagcatggat
2041 ctgggaacaa caccaggcga ctgtggttgc ccctacatct ataagagagg aaatgactac
2101 attgtcattg gagtccacac agcagctgcc cgtggtggaa acacagtcat ctgtgcaacc
2161 caaggtggcg aaggtgaggc cacacttgaa ggtggtgaca acaagggaac ctacttgcct
2221 gtcgctctat cttcggcgct gcttgggtgt ttaaccagca ccaagacgaa gttttggaga
2281 tcatccacaa cgccactccc accaggcacc tacgagccag cctacctcgg tggcaaggat
2341 cccagagtca aaggtggtcc ttcattgcaa caagttatga gggaccagct aaagccattc
2401 acagaaccca gaggcaaacc accaagacca aatgtgttgg aagctgccaa gaaaaccatc
2461 attaatgttc ttgagcaaac aattgaccca ccccaaaaat ggtcattcgc gcaagcatgc
2521 gcatcccttg acaaaaccac ctccagcggc cacccacacc acatgcggaa aaacgattgc
2581 tggaatgggg agtcctttac aggaaaattg gcagatcagg cctccaaggc caacctaatg
2641 tttgaagagg ggaagaacat gactccagtc tacacaggtg cacttaaaga tgaactggtg
2701 aagactgaca aaatttatgg taagatcaag aagaggctcc tgtggggctc ggacctggcg
2761 accatgatac ggtgcgcccg ggcttttggg ggcctcatgg atgaactcaa ggctcactgt
2821 gtcacccttc ctgtcagagt tggtatgaac atgaatgagg atggccccat aatctttgag
2881 aagcactcca gatataaata tcactatgat gctgattact ccaggtggga ctcaacacaa
2941 caaagggatg tgctagcagc agcactagaa atcatggtta agttttctcc agaaccgcac
3001 ttggcccaga tagttgcaga agacctcctt tcccctagtg taatggatgt gggtgacttt
3061 caaatatcaa taagtgaggg gcttccttcc ggggtgcctt gcacctccca atggaactcc
3121 atcgcccact ggctcctcac cctttgtgca ctctctgaag tcacggacct gtctcctgac
3181 atcatccagg ccaactccct tttctccttc tatggtgatg acgagattgt gagtacagac
3241 ataaagttgg acccagagaa gctgacagca aaactcaagg agtacgggct gaagccaacc
3301 cgccctgaca aaactgaggg accccttgtt atctctgaag atctggatgg cctgacattc
3361 ctccggagga ctgtgacccg tgatccagct ggctggtttg gaaaattgga acaaagctca
3421 attctcaggc aaatgtactg gaccagaggt cccaaccatg aagatccatc tgagacaatg
3481 ataccacact cccaaagacc catacaattg atgtccttgc tgggcgaggc tgcactccac
3541 ggcccagcat tttacagcaa aattagcaaa ttggtcattg cagaattgaa ggaaggtggc
3601 atggattttt acgtgcccag gcaagagcca atgttcagat ggatgagatt ctcagatctg
3661 agcacgtggg agggcgatcg caatctggct cccagttttg tgaatgaaga tggcgtcgag
3721 tgacgccaac ccatctgatg ggtccgcagc caacctcgtc ccagaggtca acaatgaggt
3781 tatggctctg gagcccgttg ttggtgccgc tattgcggca cctgtagcgg gccaacaaaa
3841 tgtaattgac ccctggatta gaaataattt tgtgcaagcc cctggtggag agtttacagt
3901 atcccctaga aacgctccag gtgaaatact atggagcgcg cccttaggcc ccggtctaaa
3961 tccctaccta tcccatttgg ccagaatgta caatggttat gcaggtggtt ttgaagtgca
4021 ggtaattctc gcggggaacg cgttcaccgc tgggaaggtc atatttgccg cagtcccacc
4081 aaatttccca actgaaggct tgagccccag ccaggtcact atgttccccc atatagtagt
4141 ggatgttagg caactagaac ctgtgttgat tcccctaccc gacgttagga acaatttcta
4201 tcactacaat cagtcaaatg accccactat taagttgata gcaatgctgt atacaccact
4261 tagggctaat aatgctgggg acgatgtctt cacagtctct tgccgagtcc tcacaagacc
4321 atcccccgat tttgatttta tattcctagt gccacccaca gttgagtcaa gaactaagca
4381 attctctgtc ccaatcttaa ctgttgagga gatgaccaat tcaagattcc ccattccctt
4441 ggaaaagttg ttcacgggtc ccagcagtgc ctttgttgtt caaccacaaa acggcaggtg
4501 cacgactgat ggcgtgctcc taggcaccac ccaactgtct cctgtcaaca tctgcacctt
4561 cagaggggat gtcacccaca ttacaggtag tcgtaattat acaatgaatt tagcttctca
4621 aaattggaac aattatgacc caacagaaga aatcccagcc cctctaggaa ctccagattt
4681 tgtagggaag attcaaggta tgctcaccca aaccacaagg acagatggct caacacgcgg
4741 ccacaaagcc acagtgtaca ctgggagcgc cgactttgct ccaaaattgg gtagaattca
4801 atttcaaact gacacagatc gtgattttga agttcaccaa aacacaaagt tcaccccagt
4861 cggtgtcatc caagatggtg gcaccaccca ccgaaatgaa ccccaacagt gggtgctccc
4921 aagttactca ggcagggaca cccccaatgt gcatttggcc cccgctgtag cccccacttt
4981 tccgggtgaa caacttcttt tcttcagatc taccatgccc ggatgcagcg ggtaccccaa
5041 tatgaatctg gactgcctgc tcccccagga atgggtgcag tacttctacc aagaggcagc
5101 cccagcacaa tctgatgtag ctctgctgag atttgtgaat ccagatacag gtagggtttt
5161 gtttgagtgt aagcttcata aatcaggcta tgttacagtg gctcacactg gccagcatga
5221 tttggttatc ccccccaatg gttattttag gtttgattcc tgggtcaacc agttctacac
5281 gcttgccccc atgggaaatg gaacggggcg tagacgtgcg gtataatggc tggagctttc
5341 tttgctggat tggcatctga tgtccttggc tctggacttg gttcccttat caatgctggg
5401 gctggggcca tcaaccaaaa agttgagttt gaaaataaca gaaaattaca acaagcatcc
5461 ttccaattta gcagtaatct acaacaggct tccttccaac atgacaaaga gatgctccag
5521 gcacaaattg aggccaccaa acaactacaa caggaaatga tgaaagttaa acaggcagtg
5581 ctcctagagg gtgggttctc tgagacagat gcagcccgcg gggcaatcaa cgcccccatg
5641 aca
//