Typing tool
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Typing tool
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Complete norovirus genomes
| MW019958 | GII.4 | |
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| GII.P31 |
ORF1: 1..5097
ORF2: 5078..6700
ORF3: 6700..7017
LOCUS MW019958 7017 bp RNA linear VRL 29-DEC-2020
DEFINITION Norovirus GII isolate 1137 nonstructural polyprotein (ORF1) gene,
partial cds; VP1 (ORF2) gene, complete cds; and VP2 (ORF3) gene,
partial cds.
ACCESSION MW019958
VERSION MW019958.1
KEYWORDS .
SOURCE Norovirus GII
ORGANISM Norovirus GII
Viruses; Riboviria; Orthornavirae; Pisuviricota; Pisoniviricetes;
Picornavirales; Caliciviridae; Norovirus; Norwalk virus.
REFERENCE 1 (bases 1 to 7017)
AUTHORS Makhaola,K., Moyo,S. and Kebaabetswe,L.P.
TITLE Next Generation Sequencing of Near-Full Length Genome of Norovirus
GII.4 from Botswana
JOURNAL Unpublished
REFERENCE 2 (bases 1 to 7017)
AUTHORS Makhaola,K., Moyo,S. and Kebaabetswe,L.P.
TITLE Direct Submission
JOURNAL Submitted (20-SEP-2020) Biosciences and Biotechnology, Botswana
International University of Science and Technology, Khurumela,
Palapye 00, Botswana
COMMENT ##Assembly-Data-START##
Assembly Method :: Genome Detective v. 1.126
Sequencing Technology :: Oxford Nanopore(MinION)
##Assembly-Data-END##
FEATURES Location/Qualifiers
source 1..7017
/organism="Norovirus GII"
/mol_type="genomic RNA"
/isolate="1137"
/isolation_source="stool"
/host="Homo sapiens"
/db_xref="taxon:122929"
/country="Botswana: Gaborone"
/collection_date="25-Sep-2018"
/note="genotype: GII.4 Sydney[GII.P31]"
gene <1..5097
/gene="ORF1"
CDS <1..5097
/gene="ORF1"
/codon_start=1
/product="nonstructural polyprotein"
/protein_id="QNT54368.1"
/translation="KMASNDASAAAVANGNNDIAKSSSDNVLSSMAITFKRALGARPK
QPPPKEIPPRPPRPPTPELVKKIPPPPPNGEDELVVSYSAKDGISGLPDLTTVSQPEE
NNTAFSVPPLNQRENRDAKEPLTGTIIEMWDGEIYHYGLYVERGLILGVHKPPAAISL
AKVELTPLSLFWRPVYTPQYLISPDTLRRLHGESFPYTAFDNNCYAFCCWVLDLNDSW
LSRRMIQRTTGFFRPYQEWNRKPLPTMDDSKLKKVANIFLCTLSSLFTRPIKDIIGKV
KPLNILNILASCDWTFPGIVESLILLAELFGVFWTPPDVSAMIAPLLGDYELQGPEDL
AVELVPVVMGGIGLVLGFTKEKIGKMLSSAASTLRACKDLGAYGLEILKLVMKWFFPK
KEEANELAMVRSIEDAVLDLEAIENNHMTALLKDKDSLATYMRTLDLEEEKARKLSTK
SASPDIVGTINALLARIAAARSLVHRAKEELSSRPRPVVVMISGKPGIGKTHLARELA
KKIAASLTGDQRVGLIPRNGVDHWDAYKGERVVLWDDYGMSNPIHDALRLQELADTCP
LTLNCDRIENKGKVFDSDAIIITTNLANPAPLDYVNFEACSRRIDFLVYAEAPEVEKA
KRDFPGQPDMWKNAFSPDFSHIKLALAPQGGFDKNGNTPHGKGVMKTLTTGSLIARAS
GLLHERLDEYELQGPVLTTFNFDRNKVLAFRQLAAENKYGLMDTMRVGKQLKDVKTMP
DLKQALKNVAIKKCQIVYNGSTYTLEADGKGSVKVDKVQSATVQTNNELAGALHHLRC
ARIRYYVKCVQEALYSIIQIAGAAFVTTRIAKRMNIQNLWSKPQVEDTEETASKDGCP
KPKDDEEFVVSSDDIKTEGKKGKNKSGRGKKHTAFSSKGLSDEEYDEYKRIRDERNGK
YSIEEYLQDRDKYYEEVAIARATEEDFCEEEEAKIRQRIFRPTRKQRKEERASLGLVT
GTEIRKRNPEDFKPKGKLWADDDRSVDYNEKLNFEAPPSIWSRIVNFGSGWGFWVSSN
LLITTTHVLPKGVKELFGVEIKQIQVHKSGEFCRFRFPRSIRPDVTGLVLEEGAPEGT
VCSILIKRPTGEMIPLAVRMGTHASMKIQGRTVGGQMGMLLTGANAKNMDLGTGPGDC
GCPYIYKRGNDIVVAGVHTAAARGGNTVICATQGQDGEAVLEGGEDRGTYCGAPILGP
GKAPKLSTKTKFWRSSTTPLPPGTYEPAYLGGKDPRVKGGPSLQQVMRDQLKPFTEPR
GKPPRPNVLEAAKKTIINVLEQTIDPPQKWSFAQACASLDKTTSSGHPHHMRKNDCWN
GESFTGKLADQASKANLMFEEGKNMTPVYTGALKDELVKTDKIYGKVKKRLLWGSDLA
TMIRCARAFGGLMDELKAHCVTLPVRVGMNMNEDGPIIFEKHSRYRYHYDADYSRWDS
TQQRDVLAAALEIMVKFSPEPHLAQIVAEDLLSPSVMDVGDFQISISEGLPSGVPCTS
QWNSIAHWLLTLCALSEVTDLSPDIIQANSLFSFYGDDEIVSTDIKLDPEKLTAKLKE
YGLKPTRPDKTEGPLVISEDLDGLTFLRRTVTRDPAGWFGKLEQSSILRQMYWTRGPN
HEDPSETMIPHSQRPIQLMSLLGEAALHGPAFYSKISKLVIAELKEGGMDFYVPRQEP
MFRWMRFSDLSTWEGDRNLAPSFVNEDGVE"
mat_peptide <1..987
/gene="ORF1"
/product="p48"
mat_peptide 988..2085
/gene="ORF1"
/product="NTPase"
mat_peptide 2086..2622
/gene="ORF1"
/product="p22"
mat_peptide 2623..3021
/gene="ORF1"
/product="VPg"
mat_peptide 3022..3564
/gene="ORF1"
/product="Pro"
mat_peptide 3565..5094
/gene="ORF1"
/product="RdRp"
gene 5078..6700
/gene="ORF2"
CDS 5078..6700
/gene="ORF2"
/note="major capsid protein"
/codon_start=1
/product="VP1"
/protein_id="QNT54369.1"
/translation="MKMASSDANPSDGSAANLVPEVNNEVMALEPVVGAAIAAPVAGQ
QNVIDPWIRNNFVQAPGGEFTVSPRNAPGEILWSAPLGPGLNPYLSHLARMYNGYAGG
FEVQVILAGNAFTAGKVIFAAVPPNFPTEGLSPSQVTMFPHIVVDVRQLDPVLIPLPD
VRNNFYHYNQSNDPTIKLIAMLYTPLRANNAGDDVFTVSCRVLTRPSPDFDFIFLVPP
TVESRTKQFSVPILTVEEMTNSRFPIPLEKLFTGPSSAFVVQPQNGRCTTDGVLLGTT
QLSPVNICTFRGDLTHIANSHNYTMNLASQNWNNYDPTEEIPAPLGTPDFVGKIQGVL
TQTTRADGSTRGHKATVLTGSADFAPKLGRIQFQTDTDRDFEAHQNTKFTPVGVIQDG
GTTHQNEPQQWVLPSYSGRDTPNVHLAPAVAPTFPGEQLLFFRSTMPGCSGYPNMDLD
CLLPQEWVQYFYQEAAPAQSDVALLRFVNPDTGRVLFECKLHKSGYVTVAHTGQHDLV
IPPNGYFRFDSWVNQFYTLAPMGNGTGRRRAV"
gene 6700..>7017
/gene="ORF3"
CDS 6700..>7017
/gene="ORF3"
/note="minor structural protein; small basic protein"
/codon_start=1
/product="VP2"
/protein_id="QNT54370.1"
/translation="MAGAFFAGLASDVLGSGLGSLINAGAGAINQKVEFENNRKLQQA
SFQFSSNLQQASFQHDKEMLQAQIEATKKLQQEMMKVKQAVLLEGGFSETDAARGAIN
APMT"
ORIGIN
1 aagatggcgt ctaacgacgc ttccgctgcc gctgttgcca atggcaacaa cgacatcgca
61 aaatcttcaa gtgacaatgt gctttctagc atggctatca cttttaaacg agctctcggg
121 gcgcggccta aacagccgcc cccgaaggaa ataccaccca gacctccacg accacccaca
181 ccagaattgg tcaaaaagat cccccctccc ccacccaacg gagaggatga actagtggtt
241 tcttacagcg ccaaagatgg catttccgga ttgcctgatc tgaccactgt cagccaaccg
301 gaagaaaaca acacggcgtt cagcgttccc ccgctcaatc aaagggagaa tagggacgcc
361 aaggaaccac taactggaac aattatagag atgtgggatg gagaaatcta ccattacggt
421 ctgtacgtgg aacgaggtct tatacttggt gtgcacaagc caccggcagc catcagcctt
481 gccaaggtcg agttaacacc actctctttg ttctggagac ctgtgtatac ccctcagtac
541 ctcatctctc cagacactct taggagacta catggagagt cattccccta tactgcattt
601 gacaacaatt gctacgcctt ctgctgttgg gtgttagacc taaacgactc atggctgagt
661 aggagaatga ttcagaggac tacaggattc ttcagaccat accaggaatg gaacaggaaa
721 cccctcccca ctatggatga ttccaaactg aaaaaggtgg ccaacatatt cttgtgcacc
781 ctatcttcac tgttcaccag acccattaag gacataatag gaaaagtgaa acctcttaac
841 atcctcaata tcctggcctc atgtgattgg actttcccag gcatagtgga atccctaata
901 ctcttggcag agctctttgg agttttctgg acacccccag atgtgtctgc gatgatcgcc
961 cctttactag gtgattatga actgcaagga cctgaggacc ttgcagtaga actggtccca
1021 gtggtgatgg gagggatagg cttggtgcta ggatttacca aagagaaaat tggaaagatg
1081 ctgtcgtccg ccgcatccac cttaagggct tgcaaagacc ttggtgcata cggactagaa
1141 attttgaaat tggtcatgaa atggttcttc ccaaagaaag aggaagcaaa tgagctggcc
1201 atggtgagat ccatcgagga cgcagtactg gacctcgagg caattgaaaa caaccacatg
1261 accgccctgc tcaaggataa agacagcttg gcaacctaca tgagaaccct tgaccttgag
1321 gaggagaaag ccagaaaact ctcaaccaaa tctgcttcac ctgacattgt gggtacaatc
1381 aacgctcttc tggcacgaat cgctgctgca cgttccctag tgcatcgggc gaaagaagag
1441 ctctccagca ggccgagacc tgttgttgtg atgatatcgg gaaaaccagg gatagggaaa
1501 acccaccttg ccagggagtt ggccaagaag atcgcagcct ccctcacagg ggaccagcgt
1561 gtgggcctga tcccacgcaa tggcgttgac cactgggacg catacaaggg tgaaagagtt
1621 gtcctatggg acgactatgg gatgagcaac cccatacacg atgccctcag gttgcaggaa
1681 cttgctgaca cttgccccct cacgctaaat tgtgacagga ttgagaacaa aggaaaagtc
1741 tttgatagtg atgccataat tatcaccacc aatctggcca acccagcacc actggattat
1801 gtcaattttg aagcgtgctc gaggcgcatt gatttcctcg tgtacgcgga ggctcctgag
1861 gtggagaagg caaaacgcga cttcccaggc caacctgaca tgtggaagaa cgctttcagt
1921 cctgacttct cacacataaa actggcattg gctccacagg gtggttttga caagaacggc
1981 aacaccccgc atggaaaagg tgttatgaag actctcacca ctggctccct cattgcccga
2041 gcatcaggat tactccatga gagactagat gaatatgaat tacaaggccc agtcctcact
2101 accttcaact ttgaccgcaa caaggtgctt gcattcagac agcttgctgc tgaaaacaag
2161 tatgggttga tggacacaat gagagttgga aaacagctta aggatgtcaa gaccatgcca
2221 gaccttaaac aagcactcaa gaatgtcgcg atcaagaagt gccagatagt gtataatggt
2281 agcacctaca cgcttgaggc cgatggcaag ggtagtgtga aggttgacaa agtgcagagt
2341 gccaccgtgc aaactaacaa tgaactagcc ggcgccctgc accacctgag gtgcgccaga
2401 atcaggtact atgtcaagtg tgtccaggag gcattgtatt ccatcatcca aatcgctggg
2461 gccgcgtttg tcaccacgcg catcgccaag cgcatgaaca tacaaaacct ctggtccaag
2521 ccacaggtgg aagacacaga agagacggcc agcaaagatg gttgcccaaa acccaaagat
2581 gatgaagagt tcgtcgtttc atccgacgac atcaagactg agggcaagaa agggaagaac
2641 aagtccggcc gtggcaagaa gcacacagcc ttctcaagca aagggctcag tgatgaggag
2701 tacgatgagt acaagagaat cagagatgaa aggaatggta agtactccat agaagagtac
2761 cttcaggaca gagacaagta ctatgaggag gtggccattg ccagggcaac tgaagaggac
2821 ttctgtgaag aagaagaggc caaaatccgg cagagaattt ttagaccaac aaggaaacaa
2881 cgtaaagaag agagggcctc tttaggcttg gtcacaggca cagagatcag gaagagaaac
2941 ccagaagact tcaaacccaa gggaaagctg tgggctgatg atgacagaag tgttgactac
3001 aacgagaaac tcaactttga ggccccacca agcatctggt cgcggatagt caactttggt
3061 tcaggttggg gcttctgggt ttcatccaac cttctgatca caacaacaca tgttctgcct
3121 aaaggggtta aggaactctt tggagttgaa attaaacaaa tccaagtcca caagtctgga
3181 gagttctgca gattcagatt cccgagatcc attaggccag atgtcacagg acttgtgctg
3241 gaggaaggag ccccagaagg cactgtctgt tccatactca taaaaaggcc tacaggtgag
3301 atgatcccct tggcagtgag gatgggcaca catgcatcca tgaaaataca gggccggacc
3361 gttggtggcc agatgggaat gctcttaaca ggggcgaatg caaagaacat ggatctcggc
3421 actggtcctg gtgactgcgg ttgtccctac atctacaaac gcggcaacga cattgttgtc
3481 gcgggtgttc acaccgcagc agcccgggga ggcaacactg tcatatgtgc cacccaaggg
3541 caggatgggg aggcagtcct tgagggaggt gaggaccgtg gcacctactg tggcgcccca
3601 attctgggcc ctggcaaggc gcccaaactc agcaccaaga cgaaattctg gagatcatcc
3661 acaacgccac tcccaccagg cacctacgaa ccagcctacc tcggtggcaa ggaccccaga
3721 gtcaaaggtg gcccttcact gcaacaagtt atgagggacc agctaaaacc attcacagaa
3781 cctagaggca aaccaccaag accaaatgtg ttggaagctg ccaagaaaac catcattaat
3841 gttcttgagc aaacaattga cccaccccaa aaatggtcat tcgcgcaagc ttgcgcatcc
3901 cttgacaaaa ccacctccag cggccaccca caccacatgc ggaaaaacga ttgttggaat
3961 ggggagtcct ttacaggtaa attggcagac caggcctcca aggccaacct aatgtttgaa
4021 gagggaaaga acatgactcc agtctacaca ggtgcactta aggatgaact ggtgaagact
4081 gacaaaattt atggcaaggt caagaagagg ctcctgtggg gctcggacct ggcgaccatg
4141 atacggtgcg cccgggcttt tggaggtctc atggatgaac tcaaggcaca ctgtgttacc
4201 cttcctgtca gagttggtat gaacatgaat gaggatggcc ccataatctt tgagaagcac
4261 tccaggtata ggtatcacta tgacgctgac tactccaggt gggactcaac acaacaaagg
4321 gatgtgctag cagcagcact agaaatcatg gttaagtttt ctccagagcc acacttggcc
4381 cagatagttg cagaagacct cctctcccct agtgtaatgg atgtgggtga cttccaaata
4441 tcaataagtg agggactccc ctccggggtg ccttgcacct cccaatggaa ctccatcgcc
4501 cactggctcc tcaccctttg tgcactctca gaagtcacag acctgtcccc tgacatcatc
4561 caggccaact cccttttctc cttctatggt gatgatgaga ttgtgagtac agacataaaa
4621 ttggacccag agaaactgac agcaaaactc aaagagtacg ggctgaagcc aacccgcccc
4681 gacaaaactg aaggacccct tgttatctct gaagatctgg atggcctgac cttcctccgg
4741 aggactgtga cccgtgaccc agctggttgg tttggaaaat tggaacagag ctcaattctc
4801 aggcaaatgt attggaccag gggccccaac catgaagatc catctgaaac aatgatacca
4861 cactcccaaa gacccataca attgatgtcc ttgctgggcg aggctgcact ccacggccca
4921 gcattttaca gcaaaattag caaattggtc attgcagaat tgaaagaagg tggcatggat
4981 ttttacgtgc ccaggcaaga gccaatgttc agatggatga gattctcaga tctgagcacg
5041 tgggagggcg atcgcaatct ggctcccagt tttgtgaatg aagatggcgt cgagtgacgc
5101 caacccatct gatgggtccg cagccaacct cgtcccagag gtcaacaatg aggttatggc
5161 tctggagccc gttgttggtg ccgctatcgc ggcacctgta gcgggccaac aaaatgtaat
5221 tgacccctgg attagaaata attttgtgca agcccctggt ggagagttta cagtatcccc
5281 tagaaacgct ccaggtgaaa tactatggag cgcgccctta ggccccggtc taaatcccta
5341 cctatcccat ttggccagaa tgtacaatgg ttatgcaggt ggttttgaag tgcaggtaat
5401 cctcgcgggg aacgcgttca ccgctgggaa ggtcatattt gcagcagtcc caccaaattt
5461 tccaactgaa ggcctgagcc ccagccaggt caccatgttc ccccatatag tagtggatgt
5521 taggcaatta gaccctgtgt tgattccctt acccgacgtt aggaacaatt tctaccacta
5581 caaccaatca aatgacccca ccattaagtt gatagcaatg ctttatacac cacttagggc
5641 taataatgct ggggacgatg tcttcacagt ctcttgccgg gtcctcacga gaccatcccc
5701 cgactttgat tttatattcc tagtgccacc cacagttgag tcaagaacta agcaattctc
5761 tgttccaatc ttaactgttg aggagatgac caattcaaga ttccccattc ctttggaaaa
5821 gttgttcacg ggtcccagca gtgcttttgt tgttcaacca caaaacggca ggtgcacaac
5881 tgatggcgtg ctcctaggca ccacccaact gtctcctgtc aacatctgca ccttcagagg
5941 agatctcact cacatcgcaa atagtcataa ttacacaatg aatttggctt ctcaaaattg
6001 gaacaattat gacccaacag aagaaatccc agcccctcta ggaactccag attttgtagg
6061 gaagatacaa ggagtgctca cccaaaccac aagggcggat ggctcaacac gcggccacaa
6121 agccacagtg ctcactggga gcgccgattt tgctccaaaa ctgggtagaa ttcaatttca
6181 aactgacaca gatcgtgatt ttgaagctca ccaaaacaca aagttcaccc cagtcggtgt
6241 catccaagat ggtggcacca cccatcaaaa tgaaccccaa cagtgggtgc tcccaagtta
6301 ctcaggcagg gacaccccca atgtgcattt ggcccccgct gtagccccca cttttccggg
6361 tgagcaactt cttttcttca gatccaccat gcccggatgc agcgggtacc ccaatatgga
6421 tttggactgt ctactccccc aggaatgggt gcagtacttc taccaagagg cagccccagc
6481 acaatctgat gtggctctgc taagatttgt gaatccagac acaggtaggg ttttgtttga
6541 gtgtaagctt cataagtcag gctatgttac agtggctcac actggccaac atgatttggt
6601 tatccccccc aatggttatt ttaggtttga ttcctgggtc aaccagttct acacgcttgc
6661 ccccatggga aatggaacgg ggcgtagacg tgcagtataa tggctggagc tttctttgct
6721 ggattggcat ctgatgtcct tggctctgga cttggttccc ttatcaatgc tggggctggg
6781 gccatcaacc aaaaagttga gtttgaaaat aacagaaaat tacaacaagc atccttccaa
6841 tttagcagta atctacaaca ggcttccttc caacatgaca aagagatgct ccaggcacaa
6901 attgaggcca ccaaaaagct acaacaggaa atgatgaaag ttaaacaggc agtgctccta
6961 gagggtgggt tctctgagac agatgcagcc cgcggggcaa tcaacgcccc catgaca
//