Typing tool
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Typing tool
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Complete norovirus genomes
| MW019956 | GII.4 | |
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| GII.P31 |
ORF1: 1..5097
ORF2: 5078..6700
ORF3: 6700..7017
LOCUS MW019956 7017 bp RNA linear VRL 29-DEC-2020
DEFINITION Norovirus GII isolate 1048 nonstructural polyprotein (ORF1) gene,
partial cds; VP1 (ORF2) gene, complete cds; and VP2 (ORF3) gene,
partial cds.
ACCESSION MW019956
VERSION MW019956.1
KEYWORDS .
SOURCE Norovirus GII
ORGANISM Norovirus GII
Viruses; Riboviria; Orthornavirae; Pisuviricota; Pisoniviricetes;
Picornavirales; Caliciviridae; Norovirus; Norwalk virus.
REFERENCE 1 (bases 1 to 7017)
AUTHORS Makhaola,K., Moyo,S. and Kebaabetswe,L.P.
TITLE Next Generation Sequencing of Near-Full Length Genome of Norovirus
GII.4 from Botswana
JOURNAL Unpublished
REFERENCE 2 (bases 1 to 7017)
AUTHORS Makhaola,K., Moyo,S. and Kebaabetswe,L.P.
TITLE Direct Submission
JOURNAL Submitted (20-SEP-2020) Biosciences and Biotechnology, Botswana
International University of Science and Technology, Khurumela,
Palapye 00, Botswana
COMMENT ##Assembly-Data-START##
Assembly Method :: Genome Detective v. 1.126
Sequencing Technology :: Oxford Nanopore(MinION)
##Assembly-Data-END##
FEATURES Location/Qualifiers
source 1..7017
/organism="Norovirus GII"
/mol_type="genomic RNA"
/isolate="1048"
/isolation_source="stool"
/host="Homo sapiens"
/db_xref="taxon:122929"
/country="Botswana: Gaborone"
/collection_date="20-Mar-2017"
/note="genotype: GII.4 Sydney[GII.P31]"
gene <1..5097
/gene="ORF1"
CDS <1..5097
/gene="ORF1"
/codon_start=1
/product="nonstructural polyprotein"
/protein_id="QNT54362.1"
/translation="KMASNDASAAAAANSNNDIAKSSSDGVFSNMAVTFKRALGARPK
QPPPKEIPTRPPRPPTPELVKKIPPPPPNGEEELVVSYSAKDGVSGLPELTTVSQPEE
TNTAFSVPPLNQRENRDAKEPLTGTIIEMWDGEIYHYGLYVERGLILGVHKPPAAISL
AKVELTPLSLFWRPVYTPQYLISPDTLRRLHGESFPYTAFDNNCYAFCCWVLDLNDSW
LSRRMIQRTTGFFRPYQEWNRKPLPTMDDSKLKKVANIFLCTLSSLFTRPIKDIIGKL
KPLNILNILATCDWTFPGIVESLILLAELFGVFWTPPDVSAMIAPLLGDYELQGPEDL
AVELVPVVMGGIGLVLGFTKEKIGKMLSSAASTLRACKDLGAYGLEILKLVMKWFFPK
KEEANELAMVRSIEDAVLDLEAIENNHMTTLLKDKDSLATYMRTLDLEEEKARKLSTK
SASPDIVGTINALLARIAAARSLVHRAKEELSSRPRPVVVMISGKPGIGKTHLARELA
RKIAASLTGDQRVGLIPRNGVDHWDAYKGERVVLWDDYGMSNPIHDALRLQELADTCP
LTLNCDRIENKGKVFDSDAIIITTNLANPAPLDYVNFEACSRRIDFLVYAEAPEVEKA
KRDFPGQPDMWKNAFSPDFSHIKLALAPQGGFDKNGNTPHGKGVMKTLTTGSLIARAS
GLLHERLDEYELQGPVLTTFNFDRNKILAFRQLAAENKYGLMDTMRVGKQLKDVKTMP
DLKQALKNVAIKKCQIVYNGSTYTLEADGKGSVKVDKVQSATVQTNNELAGALHHLRC
ARIRYYVKCVQEALYSIIQIAGAAFVTTRIAKRMNIQNLWSKPQVEDTEETASKDGCP
KPKDDEEFVVSSDDIKTEGKKGKNKSGRGKKHTAFSSKGLSDEEYDEYKRIRDERNGK
YSIEEYLQDRDKYYEEVAIARATEEDFCEEEEAKIRQRIFRPTKKQRKEERASLGLVT
GSDIRKRNPDDFKPKGKLWADDTRSVDYNERLDFEAPPSVWSRIVPLGTGWGFWVSSN
LLITTTHVLPKGVKELFGVEIKQIQVHKSGEFCRFRFPRSIRPDVTGLVLEEGAPEGT
VCSILIKRPTGEMIPLAVRMGTHASMKIQGRTVGGQMGMLLTGANAKNMDLGTGPGDC
GCPYIYKRGNDIVVAGVHTAAARGGNTVICATQGQDGEAVLEGGEDRGTYCGAPILGP
GKAPKLSAKTKFWRSSPDALPPGTYEPAYLGGKDPRVEKGPSLQQVMRDQLKPFTEPR
GKPPRPAVLEEAKKTVMNVLEQTIDPPQPWSYSQACASLDKTTSSGHPHHVKKNDHWN
GESFTGPLADQASKANLMYEQAKNMKPVYTGALKDELVKTDKIYKKIKKRLLWGSDLA
TMIRCARAFGGLMDSMKASCIALPCRVGMNMNEDGPIIFDKHSKYRYHYDADYSRWDS
TQQRSILSAALEIMVKFSPEPHLAQIVAEDLLSPSVMDVGDFQISISEGLPSGVPCTS
QWNSIAHWLLTLCALSEVTDLSPDIIQANSLFSFYGDDEIVSTDIKLDPEKLTAKLKE
YGLKPTRPDKTEGPLVISEDLDGLTFLRRTVTRDPAGWFGKLEQSSILRQMYWTRGPN
HEDPSETMIPHSQRPIQLMSLLGEAALHGPAFYSKISKLVIAELKEGGMDFYVPRQEP
MFRWMRFSDLSTWEGDRNLAPSFVNEDGVE"
mat_peptide <1..987
/gene="ORF1"
/product="p48"
mat_peptide 988..2085
/gene="ORF1"
/product="NTPase"
mat_peptide 2086..2622
/gene="ORF1"
/product="p22"
mat_peptide 2623..3021
/gene="ORF1"
/product="VPg"
mat_peptide 3022..3564
/gene="ORF1"
/product="Pro"
mat_peptide 3565..5094
/gene="ORF1"
/product="RdRp"
gene 5078..6700
/gene="ORF2"
CDS 5078..6700
/gene="ORF2"
/note="major capsid protein"
/codon_start=1
/product="VP1"
/protein_id="QNT54363.1"
/translation="MKMASSDANPSDGSAANLVPEVNNEVMALEPVVGAAIAAPVAGQ
QNVIDPWIRNNFVQAPGGEFTVSPRNAPGEILWSAPLGPDLNPYLSHLARMYNGYAGG
FEVQVILAGNAFTAGKVIFAAVPPNFPTEGLSPSQVTMFPHIVVDVRQLEPVLIPLPD
VRNNFYHYNQSNDPTIKLIAMLYTPLRANNAGDDVFTVSCRVLTRPSPDFDFIFLVPP
TVESRTKPFSVPVLTVEEMTNSRFPIPLEKLFTGPSSAFVVQPQNGRCTTDGVLLGTT
QLSPVNICTFRGDVTHITGSRNYTMNLASLNWNSYDPTEEIPAPLGTPDFVGKIQGML
TQTTRTDGSTRGHKATVYTGSADFSPKLGRVQFETDTDHDFEANQNTKFTPVGVIQDG
STTHRNEPPKWVLPSYSGRNTPNVHLAPAVAPTFPGEQLLFFRSTMPGCSGVPNMDLD
CLLPQEWVQYFYQEAAPAQSDVALLRFVNPDTGRVLFECKLHKSGYVTVAHTGQHDLV
IPPNGYFRFDSWVNQFYTLAPMGNGTGRRRVV"
gene 6700..>7017
/gene="ORF3"
CDS 6700..>7017
/gene="ORF3"
/note="minor structural protein; small basic protein"
/codon_start=1
/product="VP2"
/protein_id="QNT54364.1"
/translation="MAGAFFAGLASDVLGSGLGSLINAGAGAINQKVEFENNRKLQQA
SFQFSSNLQQASFQHDKEMLQAQIDATKKLQQEMMKVKQAMLLEGGFSETDAARGAIN
APMT"
ORIGIN
1 aagatggcgt ctaacgacgc ttccgctgcc gctgctgcca acagcaacaa cgacatcgca
61 aaatcttcaa gtgacggtgt gttttctaac atggctgtca cttttaaacg ggccctcggg
121 gcgcggccta aacaaccgcc cccgaaggaa ataccaacca gacccccacg accacccaca
181 ccggaattgg tcaaaaagat cccccctccc ccacccaacg gggaggaaga attagtggtt
241 tcttacagcg ccaaagacgg cgtttccgga ttgcctgagc ttaccactgt cagccaaccg
301 gaagaaacca atacggcgtt cagtgttccc ccgctcaatc aaagggagaa tagggacgcc
361 aaggaaccac taactgggac aattattgaa atgtgggatg gagaaatcta ccattacggc
421 ctgtacgtgg aacgaggtct tatacttggt gtgcacaagc caccagcagc catcagcctt
481 gccaaggtcg agttaacacc actctctttg ttctggagac ctgtgtacac cccccagtat
541 ctcatctctc cagacactct caggagacta catggagagt cattccccta caccgcattt
601 gacaacaatt gctacgcctt ctgctgttgg gtattagacc taaacgactc atggctaagt
661 aggagaatga ttcagagaac aacaggtttc ttcagaccat accaggagtg gaacaggaaa
721 cccctcccca ctatggatga ctccaaattg aagaaggtag ccaacatatt cttgtgcacc
781 ctgtcctcac tattcaccag acccattaag gacataatag ggaaattgaa acctcttaac
841 attctcaata ttctggctac atgtgattgg accttcccag gtatagtgga atccctaata
901 ctcttggcag agctctttgg agttttctgg acacccccag atgtgtctgc gatgatcgcc
961 cctttgctag gtgattatga actgcaagga cctgaggacc ttgcagtgga actggtccca
1021 gtagtgatgg gggggatagg tttggtgcta ggattcacca aagagaaaat tggaaaaatg
1081 ctgtcatccg ctgcatccac tttaagagct tgtaaagacc ttggtgcata cggactggaa
1141 attttaaaac tggtcatgaa gtggttcttc ccaaagaaag aggaagcaaa tgagctggct
1201 atggtgagat ccattgagga cgcagtgcta gacctcgaag caattgaaaa caaccacatg
1261 accaccctac tcaaggacaa agatagcttg gcaacctaca tgagaaccct tgaccttgag
1321 gaggagaaag ctagaaaact ctcaaccaaa tctgcttcac ccgatattgt gggcacaatc
1381 aacgctcttc tggcaagaat cgctgctgca cgctccctag tgcatcgggc gaaagaagag
1441 ctctccagca ggccgagacc tgttgttgtg atgatatcgg gaaaaccagg gatagggaaa
1501 acccaccttg ccagggagtt ggccaggaag atcgcagcct ccctcacagg ggaccagcgt
1561 gtgggcctga tcccacgcaa tggcgttgac cactgggacg catacaaggg tgaaagagtt
1621 gtcctatggg acgactatgg gatgagcaac cccatacacg atgccctcag gttgcaggaa
1681 cttgctgaca cttgccccct cacgctaaat tgtgacagga ttgagaacaa aggaaaagtc
1741 tttgatagtg atgccataat tatcaccacc aatctggcca acccagcacc actggattat
1801 gtcaattttg aagcgtgctc gaggcgcatt gatttcctcg tgtacgcgga ggctcctgag
1861 gtggagaagg caaaacgcga cttcccaggc caacctgaca tgtggaagaa cgctttcagt
1921 cctgacttct cacacataaa actggcattg gctccacagg gtggttttga caagaacggc
1981 aacaccccgc atggaaaagg tgttatgaag actctcacca ctggctccct cattgcccga
2041 gcatcaggat tactccatga gagactagat gaatatgaat tacaaggccc agtcctcact
2101 accttcaact ttgaccgcaa caagatactt gcatttagac agcttgctgc tgaaaacaag
2161 tatgggttga tggacacaat gagagttgga aaacagctta aggatgtcaa gaccatgcca
2221 gaccttaaac aagcactcaa aaatgtcgcg atcaagaagt gccagatagt gtataatggt
2281 agcacctaca cgcttgaggc cgatggcaag ggtagtgtga aggttgacaa agtgcagagt
2341 gccaccgtgc aaactaacaa tgaactagcc ggcgccctgc accacctgag gtgcgccaga
2401 atcaggtact atgtcaagtg tgtccaggag gcattgtatt ccatcatcca aatcgctggg
2461 gccgcgtttg tcaccacgcg catcgccaag cgcatgaaca tacaaaacct ctggtccaag
2521 ccacaggtgg aagacacaga agagacggcc agcaaagatg gttgcccaaa acccaaagat
2581 gatgaagagt tcgtcgtttc atccgacgac atcaagactg agggcaagaa agggaagaac
2641 aagtccggcc gtggcaagaa gcacacagcc ttctcaagca aagggctcag tgatgaggag
2701 tacgatgagt acaagagaat cagagatgaa aggaatggta agtactccat agaagagtac
2761 cttcaggaca gagacaagta ctatgaggag gtggccattg ccagggcaac cgaggaagac
2821 ttctgtgagg aggaggaggc caaaataagg caaagaattt tccgcccgac aaagaaacag
2881 aggaaggagg aaagggcctc tcttggcttg gtcactggct cagacatcag gaagagaaac
2941 ccagacgact tcaaaccaaa aggcaaactg tgggcagatg acactagaag tgtggattac
3001 aatgaaaggc ttgacttcga ggcgccccca agtgtttggt caagaatagt cccattgggc
3061 accggttggg ggttctgggt ttcatccaac cttctgatca caacaacaca cgttctgcct
3121 aaaggggtta aggaactctt tggagttgaa attaaacaaa tccaagtcca caagtctgga
3181 gagttctgca gattcagatt cccgagatcc attaggccag atgtcacagg acttgtgctg
3241 gaggaaggag ccccagaagg cactgtctgt tccatactca taaaaaggcc tacaggtgag
3301 atgatcccct tggcagtgag gatgggcaca catgcatcca tgaaaataca gggccggacc
3361 gttggtggcc agatgggaat gctcctaaca ggggcgaatg caaagaacat ggatctcggc
3421 actggtcctg gtgactgcgg ttgtccctac atctacaaac gcggcaacga cattgttgtc
3481 gcgggtgttc acaccgcagc agcccgggga ggcaacactg tcatatgtgc cacccaaggg
3541 caggatgggg aggcagtcct tgagggaggt gaggaccgtg gcacctactg tggcgcccca
3601 attctgggcc ctggcaaggc gcccaaactc agcgcgaaga ctaagttttg gcgctcgtca
3661 ccagatgcct tgccgcctgg cacgtatgaa cctgcttacc tgggaggcaa ggaccccaga
3721 gtggaaaaag ggccttcctt gcagcaagtc atgagggacc aattgaaacc attcacagaa
3781 cccagaggca aaccacctag gcctgcagtt ttagaagagg ccaaaaagac agtgatgaat
3841 gttctggaac aaaccatcga cccaccccaa ccatggtcct actcgcaagc atgtgcctca
3901 ctggacaaaa ccacctctag tggtcacccc catcacgtca agaaaaacga ccactggaat
3961 ggagagtcct tcaccggtcc cttggcagac caggcatcca aagccaacct catgtatgag
4021 caggctaaga acatgaagcc agtgtataca ggtgcgctta aagatgagct tgttaagact
4081 gataagatct acaaaaagat aaagaagagg ctcctatggg gttcggacct ggcgacaatg
4141 atcaggtgcg ccagggcttt tggtggtctc atggacagca tgaaggcaag ttgtatagct
4201 ctcccatgca gggtagggat gaacatgaat gaagatggcc ccatcatatt tgacaagcat
4261 tctaagtaca ggtaccacta tgatgctgac tattctaggt gggattcaac ccagcaaagg
4321 agcattctat ctgcagcact ggaaatcatg gttaagtttt ctccagaacc acacttggcc
4381 cagatagttg cagaagacct cctttcccct agtgtaatgg atgtgggtga ctttcaaata
4441 tcaataagtg aggggcttcc ctccggggtg ccttgcacct cccagtggaa ctccatcgcc
4501 cactggctcc tcaccctttg tgcactctct gaagtcacgg acctgtctcc tgacatcatc
4561 caggccaact cccttttctc cttctatggt gatgacgaga ttgtgagtac agacataaag
4621 ttggacccag agaagctgac agcaaaactc aaggagtacg ggctgaagcc aacccgcccc
4681 gacaaaactg agggacccct tgttatctct gaagacctgg atggcctgac attcctccgg
4741 aggactgtga cccgtgatcc agctggctgg tttggaaaat tggaacaaag ctcaattctc
4801 aggcaaatgt actggaccag aggtcccaac catgaagatc catctgagac aatgatacca
4861 cactcccaaa gacccataca attgatgtcc ttgctgggcg aggctgcact ccacggccca
4921 gcattttaca gcaaaattag caaattggtc attgcagaat tgaaggaagg tggcatggat
4981 ttttacgtgc ccaggcaaga gccaatgttc agatggatga gattctcaga tctgagcacg
5041 tgggagggcg atcgcaatct ggctcccagt tttgtgaatg aagatggcgt cgagtgacgc
5101 caacccatct gatgggtccg cagccaacct cgtcccagag gtcaacaatg aggttatggc
5161 tctggagccc gttgttggtg ccgctattgc ggcacctgta gcgggccagc aaaatgtaat
5221 tgacccctgg attagaaaca attttgtaca agcccctggt ggagagttta cagtatcccc
5281 tagaaacgct ccaggtgaaa tactatggag cgcgccctta ggccctgatc taaatcccta
5341 cctatcccat ttggccagaa tgtacaatgg ttatgcaggt ggttttgaag tgcaggtaat
5401 tctcgcgggg aacgcgttca ccgctgggaa ggtcatattt gccgcagtcc caccaaattt
5461 cccaactgaa ggcttgagcc ccagccaggt cactatgttc ccccatatag tagtagatgt
5521 taggcaacta gaacctgtgt tgattcccct acccgacgtc aggaataatt tctatcacta
5581 caatcagtca aatgacccca ctattaagtt gatagcaatg ctgtatacac cacttagggc
5641 taataatgct ggggatgatg tcttcacagt ctcttgccgg gtcctcacga gaccatcccc
5701 cgattttgat tttatatttc tagtgccacc cacagttgag tcaagaacta agccattctc
5761 tgtcccggtc ttaactgttg aggagatgac caattcaaga ttccccatcc ccttggaaaa
5821 gttgttcacg ggtcccagca gtgcctttgt tgttcaaccg caaaacggca ggtgtacgac
5881 tgatggcgtg ctcctaggta ccacccaact gtctcctgtc aacatctgca ccttcagagg
5941 ggatgtcacc cacatcacag gtagtcgtaa ctacacaatg aatttggctt ctctaaattg
6001 gaacagttat gacccaacag aagaaatccc agcccctctg ggaactccag attttgtagg
6061 gaaaatccaa ggcatgctca cccaaaccac aaggacagat ggctcaacac gcggccacaa
6121 agctacagtg tacactggga gcgccgattt ttctccaaaa ttgggtagag ttcaatttga
6181 aactgacaca gaccatgatt ttgaagctaa ccaaaacaca aagttcaccc cagtcggtgt
6241 catccaagat ggcagcacca cccaccgaaa tgaaccccca aagtgggtgc tcccaagtta
6301 ctcaggcaga aacaccccta acgtgcatct ggcccccgct gtagccccca cttttccagg
6361 tgagcaactt cttttcttca gatctaccat gcccggatgc agcggggtac ccaacatgga
6421 tttggactgt ctgctccccc aggaatgggt gcagtacttc taccaagagg cagccccagc
6481 acaatctgat gtggctctgc taagatttgt gaatccagat acaggtaggg ttttgtttga
6541 gtgtaagctt cacaaatcag gctatgttac agtggctcac actggccaac atgatttggt
6601 tatccccccc aatggttatt ttaggtttga ttcttgggtc aaccagttct acacactcgc
6661 ccccatggga aatggaacgg ggcgtagacg tgtagtataa tggctggagc tttctttgct
6721 ggattggcat ctgatgtcct tggctccgga cttggttccc tcatcaatgc tggggctggg
6781 gccatcaacc aaaaagttga gtttgaaaat aacagaaaat tacaacaagc atccttccag
6841 tttagcagta atttgcaaca ggcttccttt caacatgaca aagagatgct ccaagcacaa
6901 attgatgcca ccaaaaagct acaacaggaa atgatgaaag ttaagcaggc aatgctccta
6961 gagggtgggt tttctgagac agatgcagcc cgcggggcaa tcaacgcccc catgaca
//