Typing tool
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Typing tool
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Complete norovirus genomes
| MW009072 | GII.5 | |
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| GII.P40 |
ORF1: 4..5139
ORF2: 5120..6742
ORF3: 6742..7518
LOCUS MW009072 7553 bp RNA linear VRL 21-SEP-2020
DEFINITION Norovirus GII isolate 387-1 nonstructural polyprotein (ORF1), VP1
(ORF2), and VP2 (ORF3) genes, complete cds.
ACCESSION MW009072
VERSION MW009072.1
DBLINK BioProject: PRJNA604000
KEYWORDS .
SOURCE Norovirus GII
ORGANISM Norovirus GII
Viruses; Riboviria; Orthornavirae; Pisuviricota; Pisoniviricetes;
Picornavirales; Caliciviridae; Norovirus; Norwalk virus.
REFERENCE 1 (bases 1 to 7553)
AUTHORS Yang,Z.
TITLE Direct Submission
JOURNAL Submitted (15-SEP-2020) Molecular Virology Team/Devision of
Molecular Biology, OARSA/CFSAN/FDA, 8301 Muirkirk Rd., Laurel, MD
20708, USA
COMMENT ##Assembly-Data-START##
Assembly Method :: CLC GWB v. 11
Sequencing Technology :: Illumina
##Assembly-Data-END##
FEATURES Location/Qualifiers
source 1..7553
/organism="Norovirus GII"
/mol_type="genomic RNA"
/isolate="387-1"
/isolation_source="stool"
/host="Homo sapiens"
/db_xref="taxon:122929"
/country="USA"
/collection_date="14-Nov-2018"
/note="genotype: GII.5[P40]"
gene 4..5139
/gene="ORF1"
CDS 4..5139
/gene="ORF1"
/codon_start=1
/product="nonstructural polyprotein"
/protein_id="QNS37122.1"
/translation="MKMASNDAATATAGNTSTNSVIHNQDVNSTSSLFANMTVGLKRA
LGARPKQPAPRIPSPNREGRHETTPRAPPPNKGGNANIPPIPPPPPNGEDIVIKYTKQ
DDAVEGVPTVATVDVPPTHSTAYSVPPLDQREKIEAKEPLTGSILEMWDGEIYHYGLY
VEKGLVLGVHKPPAAISFARIELTPLSLYWRTVYTPPYLIAPETLRKLHGESFPYTAF
DNNCYSFCCWVLDLNDSWLNRKFVSRTTGFYRPYQEWNRKPLPTMDEGKLKKVANVLL
CGLSGLFTRPIKDLIGKLRPLNILNIITNCDWTFPGIVEAFILLAELFGVFWTPPDIS
TFIASLLGDYEMQGPEDIAVEVVPVILGGIGMVLGFTKERIGRLLSSAASSLRACREI
GNYGIEVVKLVMKWFFPTKDETNEMDMVRAIEDAVLDFEAIQNNHMTALLKDKNSLAT
FLRELDMEEEKARKLSTKSASPDIIGTINALLARIAAARSLVHKAKEEMSSRMRPVVI
MISGRPGIGKTHLARDLAKKMAATLSGDQRVGLVPRNGVDHWDAYKGERIVLWDDYGM
SNPVTDALRLQELADTCPLTLNCDRIENKGKVFDSDTIIITTNLANPAPLDYVNFEAC
SRRIDFLVYADSPSVDKAKRDFPGQPDMWKDAFKPDFSHIKLQLAPQGGFDKNGNTPH
GKGVMKTLTTHSLIARATGLLHERLDEFDLQGPELPVYNFDHNRVAAFRRLAADNKYG
LMETIKVGNKLKSVKTLEQLKDALKDISIMPCRIVYNSMAYDLDSNGSGRVSVKKVVD
HKIQTNNELNSALNNLRGARVRYYVKCVQEMVYSLLQIAGAAFVTSRMTRRLNVSSIW
ARPEKQVEATEEPPSPPTEDWTITPANAVQEGKKGKNKSGRGKKHTAFSSKGLSDEEY
DEYKRIREERQGKYSIEEYLQDRDRYYEELAIAKATEENFCEEEEIKIRQRVFRPTRK
QRKEERATLGLVTGSEIRKRNPDDFKPRGKLWADDDRSVNYNEKIDFEAPPSLWSRIV
NFGSGWGFWVSSNLLITSTHVIPPNMTEAFGVPISQIQVHRSGEFCKMRFPKAIRPDV
SGMILEEGAPEGTVVTILIKRTTGELMPLAARMGTHATMKIQGKMLGGQMGMLLTGSN
AKNMDLGTIPGDCGCPYVYKRGNDWVVIGVHTAAARGGNTVICATQGPDGEATLEGRD
NHGTYCGAPILGPGSAPKLSTKTKFWRSSNAPLPPGTYEPAYLGGKDPRVKGGPSLQQ
VMREQLKPFTAPRGKPPRPAILEAAKETICNVLEQIIDPPQKWSYTQACASLDKTTSS
GHPHHMKKNDNWNGESFTGVLADQASKANLMFEQGKHMQPVYTAALKDELVKTSKIYE
KIKKRLLWGSDLGTMIRCARAFGGLMDEMKANCVNLPIRVGMNMNEDGPIIFEKHSKY
KYHYDADYSRWDSTQQRHILGAALEIMVRFSAEPELAQIVSEDLLAPSVVDVGDFKIT
INEGLPSGVPCTSQWNSISHWLITLCAISEISGLSPDVVQTNSCFSFYGDDEIVSTDI
KLDPMKLTNKLKEYGLIPTRPDKTEGPLIIKENLDGLTFLRRDVCRDPAGWYGKLDQS
SIMRQLFWTKGPNHEDPNETMIPHSQRPIQLMSLLGEAALHGPVFYKKVSKLVITELK
EGGMDFYVPRQEPMFRWMRFSDLSTWEGDRNLAPEGVNEDGVE"
mat_peptide 4..1044
/gene="ORF1"
/product="p48"
mat_peptide 1045..2142
/gene="ORF1"
/product="NTPase"
mat_peptide 2143..2679
/gene="ORF1"
/product="p22"
mat_peptide 2680..3063
/gene="ORF1"
/product="VPg"
mat_peptide 3064..3606
/gene="ORF1"
/product="Pro"
mat_peptide 3607..5136
/gene="ORF1"
/product="RdRp"
gene 5120..6742
/gene="ORF2"
CDS 5120..6742
/gene="ORF2"
/note="major capsid protein"
/codon_start=1
/product="VP1"
/protein_id="QNS37120.1"
/translation="MKMASNDATPSNDGAAGLVPESNNEAMALEPVVGASLAAPVTGQ
TNIIDPWIRTNFVQAPNGEFTVSPRNSPGEILVNLELGPELNPYLAHLARMYNGYAGG
MEVQVMLAGNAFTAGKVIFAAVPPYFPVENLSPSQITMFPHVVIDVRTLEPVLLPMPD
VRSTLFHFNQKDEPKMRLVAMLYTPLRSNGSGDDVFTVSCRILTRPSPEFDFTYLVPP
TVESKTKPFTLPVLTLGELSNSRFPLSIDEMVTSPNESIVVQPQNGRVTLDGELLGTT
QLQACNICSIRGKVTGQVPNEQHMWNLEVTNLNGTQFDPTDDVPAPLGVPDFAGEVFG
VLSQRNRGESNPANRAHDAVVATYSDKYTPKLGLVQIGTWNTNDVENQPTKFTPIGLN
EVANGHRFEQWTLPRYSGALTLNMNLAPAVAPLFPGERLLFFRSYVPLKGGFGNPAID
CLVPQEWVQHFYQESAPSLGDVALVRYVNPDTGRVLFEAKLHKGGFLTVSSTSTGPVV
VPANGYFRFDSWVNQFYSLAPMGTGNGRRRFQ"
gene 6742..7518
/gene="ORF3"
CDS 6742..7518
/gene="ORF3"
/note="minor structural protein; small basic protein"
/codon_start=1
/product="VP2"
/protein_id="QNS37121.1"
/translation="MAGAFIAGLAGDVLSNGLGSLINAGANAINQRAEFDFNRQLQQN
SFNHDKEMLNAQIQATKQLQADMIAIKQGVLAAGGFSPTDAARGAVNAPMTQALDWSG
TRYWAPGSMKTTSYSGKFVSMNPVRQVEFPQPKKSAAIPSSASSVSSGRTNSTNSTQS
TVVSTSSVSPSRGSSAPSTLSRATTRTSNWVEEQNRNLEPYMRGALQTTFVTPPSSRA
SSNGTVSTVPKGVLDSWTPAFNTRRQPLFAYLRKKGESQV"
ORIGIN
1 tgaatgaaga tggcgtctaa cgacgctgcc actgcgaccg ctggcaatac cagcacaaac
61 agtgtgattc acaaccaaga tgtaaattct acatctagcc tctttgccaa catgactgtt
121 ggcctgaaga gggccctggg ggcgagacca aagcaacccg ctcccaggat tccttccccc
181 aacagggagg gaagacatga aaccacccct agagctcccc ctccgaacaa ggggggtaat
241 gctaacatcc caccaatacc acccccaccg cccaacgggg aggacatagt catcaagtac
301 accaagcaag atgacgcggt tgaaggggtg cccaccgtcg ccacggttga tgttcccccc
361 acacacagca ccgcttacag tgtccccccc ctggatcaga gggaaaagat tgaagcgaag
421 gagcccttga caggttcgat acttgagatg tgggacggtg agatctacca ctatggtctc
481 tacgtggaga agggcttggt tcttggtgtg cacaaacctc cagctgccat aagctttgca
541 cgcatagaac tcacccccct ctccctatac tggagaacag tctacactcc accttacctg
601 atagccccag aaaccctaag gaagctccac ggggagtcat tcccgtatac agcctttgac
661 aacaattgtt actccttctg ctgctgggtc ctggacctga acgattcttg gctcaacaga
721 aaatttgtgt caaggacaac gggtttctac agaccctacc aagagtggaa tagaaagcct
781 ttgccaacca tggatgaagg aaagctcaag aaagtggcca atgtgcttct atgtggtctc
841 tctgggcttt tcactaggcc catcaaggac ctcataggga agttgaggcc actaaacata
901 ctaaacatca tcaccaattg cgactggacc ttccccggaa ttgtggaggc tttcatactg
961 cttgcagagc tctttggagt tttctggaca ccaccagaca tttccacctt catagcttca
1021 cttctgggtg actatgaaat gcagggccct gaggatatcg cggttgaagt cgtaccggtg
1081 atcctcggcg gcataggtat ggtacttgga ttcaccaaag aaagaattgg ccggttgctg
1141 agctctgccg cttcctcact tagagcatgc agggagatcg gcaactatgg gatagaggtg
1201 gtgaagctgg tgatgaaatg gtttttcccc accaaagatg agacaaatga gatggatatg
1261 gtgagggcaa tagaggatgc tgttcttgac tttgaagcca tacagaacaa ccacatgaca
1321 gcattgctta aagacaaaaa cagccttgca accttcctca gggagctaga tatggaagag
1381 gaaaaggcgc ggaagctatc aacaaaatct gcgtccccag atattatcgg caccataaat
1441 gcccttctag ccagaattgc cgctgctagg tccctagtcc acaaggccaa ggaagaaatg
1501 tcatctagga tgcgtcctgt tgtcatcatg atctccggcc gacccgggat agggaagacg
1561 catctggccc gcgacctggc taagaagatg gcggcgaccc tctcaggtga tcagagagtg
1621 gggctcgtgc cgaggaatgg tgttgaccat tgggacgcat ataaaggaga gaggatcgtg
1681 ctctgggacg attatggaat gagcaaccct gtgactgatg cgctgcggct ccaggagctt
1741 gccgacacat gccccctaac gctcaactgt gatagaatag aaaacaaggg aaaagtgttt
1801 gacagtgaca ctataatcat caccactaat ttggccaatc ctgctcctct agattatgtc
1861 aactttgaag cttgctcccg ccgaatcgac ttccttgtct atgcagactc cccctcggtg
1921 gacaaggcga agagagactt ccctggtcaa ccagacatgt ggaaggatgc ctttaaaccg
1981 gacttttcac acataaaact tcagttggca ccacagggag gctttgataa gaacgggaac
2041 acccctcatg ggaaaggtgt catgaaaacg ctaaccacac actcactcat tgcccgcgcc
2101 acgggcctcc tacatgaaag attggatgag tttgacctgc agggtcccga gttgcccgtg
2161 tacaattttg accacaacag ggtggctgct ttcaggagac tggcagctga caacaagtat
2221 gggcttatgg aaaccataaa ggtgggcaac aaattgaaaa gcgtcaagac tctagaacaa
2281 ctcaaggacg ctctaaaaga cataagtatc atgccttgca gaatagtcta caactcgatg
2341 gcttacgatc tcgattcgaa cggatcaggg agagtcagtg tcaaaaaggt tgtagaccac
2401 aagatccaga ccaacaacga gctcaattcc gccctcaaca atctgcgcgg tgccagagtg
2461 agatactatg ttaaatgtgt tcaagagatg gtgtattccc tccttcaaat tgctggcgca
2521 gccttcgtca cttcaagaat gacacggagg ttgaacgtca gcagcatttg ggccagacca
2581 gaaaaacagg tggaggccac tgaggaaccc ccatctcccc cgactgagga ctggactata
2641 accccagcaa atgcagtcca ggaaggtaaa aagggcaaga acaagagcgg caggggcaag
2701 aaacataccg ccttctccag taaaggccta agtgatgagg agtatgatga gtataagaga
2761 atcagagaag agagacaagg aaaatactcc atagaagaat accttcagga tagggaccgg
2821 tattatgaag aattggccat agccaaggca acagaggaga acttctgtga ggaggaagaa
2881 ataaaaatca gacagagggt cttccgtccg accaggaaac aacgcaagga agagagggca
2941 actctaggac tggtcacagg cagtgaaata aggaagagga acccagatga tttcaagcca
3001 agaggaaaat tgtgggctga tgatgaccgc agtgtaaatt acaatgagaa aatagatttt
3061 gaagcgcctc ccagcctttg gtctcgaata gtcaacttcg ggtcaggttg gggtttttgg
3121 gtttcttcca acttgctcat cacatcaaca catgtcatcc ccccgaacat gactgaggcc
3181 ttcggtgtac caataagcca gatacaagta cataggagtg gagagttctg taaaatgagg
3241 ttccccaaag ctataagacc tgatgtctca ggcatgatcc ttgaggaagg agctcccgag
3301 ggaacggtgg tgaccatact gatcaagagg accaccggtg agctcatgcc actggccgcc
3361 cgaatgggca cccacgccac catgaaaatt caagggaaaa tgcttggagg ccaaatgggc
3421 atgctcctca cggggtccaa cgctaagaac atggacctcg gtaccatccc tggagactgt
3481 ggttgtccct atgtttacaa gaggggtaac gactgggtgg ttataggggt gcacaccgca
3541 gccgccagag gtggcaacac tgtgatttgt gccactcagg gtccagacgg tgaggccacg
3601 ctcgagggga gagacaacca cgggacctac tgtggggcac caatacttgg accaggaagt
3661 gcaccaaaac tcagcactaa gactaaattc tggaggtcat ccaacgcccc acttccgcct
3721 ggcacttatg agcccgctta cctaggcgga aaagacccaa gagtcaaggg gggaccatca
3781 ctacagcaag tcatgaggga acaactcaaa cctttcacag ccccccgagg gaagccccca
3841 cgaccggcga tcctggaggc tgctaaggaa accatctgta atgtacttga acagatcatt
3901 gacccacccc aaaaatggtc ttatactcag gcctgtgcct ctctagacaa aacaacatcc
3961 agtggccatc cccaccacat gaaaaagaat gacaactgga acggagagtc ctttaccggt
4021 gtgttggctg accaagcttc caaggcaaat ctcatgtttg aacaagggaa acacatgcaa
4081 cctgtgtata ctgccgccct caaagacgag ctcgtcaaga ctagcaagat ctatgagaaa
4141 attaagaaga ggctcctatg gggttcagat ctgggcacaa tgatccgctg tgccagggct
4201 tttggaggcc tcatggatga gatgaaagca aattgtgtaa acttaccaat cagagttggc
4261 atgaacatga atgaagatgg acccatcatt ttcgagaaac attcaaagta taagtaccat
4321 tatgatgctg attactctag gtgggattca acccaacaga gacatatctt gggggctgcc
4381 cttgagataa tggttaggtt ctcagctgaa cctgaattgg cccaaattgt atctgaagat
4441 ctcctagccc ccagcgtggt ggacgttggt gacttcaaga tcaccataaa tgaaggttta
4501 ccctctggag tgccgtgcac atcacaatgg aactcaattt cccactggct aataacacta
4561 tgtgccatat cagaaatttc agggctgtcg ccagatgtgg tacaaacaaa ctcctgtttc
4621 tccttctatg gggatgatga gatagtcagc actgacatta agttagatcc catgaaatta
4681 actaacaagt tgaaggagta tggactgatc ccaacaagac cagacaagac agaggggcca
4741 ctcataatca aagaaaacct tgatggcttg acctttctga ggagggatgt gtgtcgggac
4801 ccagctggtt ggtatggaaa gcttgatcaa tcctcaatta tgagacaatt gttttggacc
4861 aaggggccca accatgaaga tcccaatgag acaatgattc cacactccca gaggcccata
4921 caactaatgt cattgctggg ggaggcagca ttacacggac cagttttcta caagaaagtc
4981 agtaaattag ttatcactga gctcaaagag ggtggaatgg atttttacgt gccaaggcaa
5041 gaacctatgt ttaggtggat gagattctct gacctcagca cttgggaggg cgatcgcaat
5101 cttgctcccg aaggtgtgaa tgaagatggc gtcgaatgac gctactccat caaatgatgg
5161 tgctgccggc ctcgtgccag aaagtaacaa tgaggcaatg gctctggaac ccgtggtggg
5221 ggcgtcttta gccgcccctg tcactggcca aactaatata atagacccct ggattagaac
5281 taattttgtc caagccccta atggtgaatt cacagtttcc cctagaaatt cccctggaga
5341 gatattggtc aatttggagt tgggtccaga actgaaccct tatctggcac atttagctag
5401 gatgtacaat ggttatgcgg gtggtatgga ggtgcaagtg atgctcgcgg ggaacgcgtt
5461 cactgctggc aaggtcatct ttgccgccgt gccaccttac tttccagtgg aaaatcttag
5521 cccttctcaa ataacaatgt tcccacatgt ggttatcgat gttagaacct tagaacctgt
5581 gctgctccca atgcctgatg tcagaagcac ccttttccac tttaatcaaa aggatgaacc
5641 taagatgaga cttgttgcca tgctctacac ccctcttcgt tctaatggct ctggtgacga
5701 tgttttcact gtttcatgta ggattcttac taggccctct cctgaattcg atttcacata
5761 cttggtgcca ccaacagtgg agtcaaagac caagccattt acactacctg tgctgacatt
5821 gggagaattg tccaattcta gattccctct ctctattgat gaaatggtca ccagccctaa
5881 tgagtccata gttgttcagc cacagaatgg tagggtcaca ctagatgggg agctgttagg
5941 cacaacccaa ctgcaagcat gtaacatttg ttccataagg gggaaagtga caggacaggt
6001 ccctaatgaa caacacatgt ggaacctgga ggttacaaac ctaaatggga cgcaatttga
6061 ccctacagat gatgtcccag cccctcttgg tgtgcccgac tttgcaggtg aggtctttgg
6121 tgtactcagt cagagaaata gaggtgaaag caatccagca aacagggctc atgatgctgt
6181 tgtggccacc tacagtgata aatacacccc taaattgggc ttagtgcaaa ttgggacttg
6241 gaacaccaac gatgttgaaa accagccaac aaaattcacc ccaattggtt tgaatgaggt
6301 cgccaatggc catcgatttg aacagtggac cttgcctagg tattctggtg ccctgacact
6361 aaatatgaac ttagctcctg ctgtggcccc gctctttcct ggagagcgtc ttcttttctt
6421 ccgctcttac gtcccattaa aaggtggatt tggaaaccct gctatagatt gtctagtgcc
6481 tcaggagtgg gtccaacatt tctatcagga atctgcccca tctctggggg atgtggcctt
6541 agtcaggtac gtcaacccag acaccgggcg cgtccttttt gaggccaaac tccataaagg
6601 tgggttcctg accgtgtcaa gcactagcac agggcctgtt gtggttccag ccaatggtta
6661 ttttagattt gattcttggg ttaatcaatt ttactctctt gcccccatgg gaactgggaa
6721 tgggcgcaga aggtttcagt aatggcagga gctttcatag caggtttagc aggtgatgtg
6781 cttagtaatg gcctcggttc gctgattaat gccggagcca atgctatcaa tcaaagagca
6841 gaatttgatt tcaataggca attgcagcaa aattcattta atcatgataa ggagatgtta
6901 aatgcccaaa ttcaagcaac aaaacagttg caggctgata tgatagcaat caaacaggga
6961 gttctagctg ctgggggttt ctcaccaact gatgcagcca gaggagctgt caatgcaccc
7021 atgacccaag cattagattg gagtggcact aggtattggg cccctggttc aatgaagacc
7081 accagctatt ctggaaagtt tgtgtccatg aatcctgtta ggcaggttga attcccgcag
7141 cccaaaaaga gtgcggccat accatcaagt gccagctctg tgtcttctgg taggactaat
7201 tccacaaatt ctacccaatc aactgttgtt agcacttcct cagtatcacc ttctaggggt
7261 tcttctgctc cttctactct atcaagggct acaaccagaa cttccaattg ggttgaggaa
7321 caaaacagga atttggaacc ctatatgagg ggtgccctcc aaacaacatt tgtcacccct
7381 ccttccagcc gggcatctag caacggtaca gtctcaactg taccaaaagg tgttttggac
7441 tcctggacac ctgcgtttaa cacccgcagg caaccgcttt tcgcttacct tcgcaagaag
7501 ggggagtcac aagtttagtg aaaagatgat tagtgattga taattgatct ttt
//