Typing tool
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Typing tool
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Complete norovirus genomes
| MW009071 | GII.4 Sydney | |
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| GII.P31 |
ORF1: 1..5092
ORF2: 5073..6695
ORF3: 6695..7501
LOCUS MW009071 7545 bp RNA linear VRL 21-SEP-2020
DEFINITION Norovirus GII isolate 510-1 nonstructural polyprotein (ORF1) gene,
partial cds; and VP1 (ORF2) and VP2 (ORF3) genes, complete cds.
ACCESSION MW009071
VERSION MW009071.1
DBLINK BioProject: PRJNA604000
KEYWORDS .
SOURCE Norovirus GII
ORGANISM Norovirus GII
Viruses; Riboviria; Orthornavirae; Pisuviricota; Pisoniviricetes;
Picornavirales; Caliciviridae; Norovirus; Norovirus norwalkense.
REFERENCE 1 (bases 1 to 7545)
AUTHORS Yang,Z., Silva,A.J., Wolfe,J., Hirneisen,K., Ruelle,S., Torres,A.,
Williams-Hill,D., Kulka,M. and Hellberg,R.S.
TITLE Direct Submission
JOURNAL Submitted (15-SEP-2020) Molecular Virology Team/Devision of
Molecular Biology, OARSA/CFSAN/FDA, 8301 Muirkirk Rd., Laurel, MD
20708, USA
COMMENT ##Assembly-Data-START##
Assembly Method :: CLC GWB v. 11
Sequencing Technology :: Illumina
##Assembly-Data-END##
FEATURES Location/Qualifiers
source 1..7545
/organism="Norovirus GII"
/mol_type="genomic RNA"
/isolate="510-1"
/isolation_source="stool"
/host="Homo sapiens"
/db_xref="taxon:122929"
/geo_loc_name="USA"
/collection_date="01-May-2015"
/note="genotype: GII.P31-GII.4"
gene <1..5092
/gene="ORF1"
CDS <1..5092
/gene="ORF1"
/codon_start=2
/product="nonstructural polyprotein"
/protein_id="QNS37117.1"
/translation="ASNDASAAAVANSNNDIAKSSSDGVFSNMAVTFKRALGARPKQP
PPKEILPRPPRPPTPELVKKIPPPPPNGEDELVVSYSAKDGVSGLPELTTVRQPEETN
TAFSVPPLNQRESRDAKEPLTGTIIEMWDGEIYHYGLYVERGLILGVHKPPAAISLAK
VELTPLSLFWRPVYTPQYLISPDTLRRLHGESFPYTAFDNNCYAFCCWVLDLNDSWLS
RRMIQRTTGFFRPYQDWNRKPLPTMDDSKLKKVANIFLCTLSSLFTRPIKDIIGKLKP
LNILNILATCDWTFAGIVESLILLAELFGVFWTPPDVSAMIAPLLGDYELQGPEDLAV
ELVPIVMGGIGLVLGFTKEKIGKMLSSAASTLRACKDLGAYGLEILKLVMKWFFPKKE
EANELAMVRSIEDAVLDLEAIENNHMTTLLKDKDSLATYMRTLDLEEEKARKLSTKSA
SPDIVGTINSLLARIAAARSLVHRAKEELSSRPRPVVVMISGRPGIGKTHLARELAKK
IAASLTGDQRVGLIPRNGVDHWDAYKGERVVLWDDYGMSNPIHDALRLQELADTCPLT
LNCDRIENKGKVFDSDAIIITTNLANPAPLDYVNFEACSRRIDFLVYAEAPEVEKAKR
DFPGQPDMWKNAFSPDFSHIKLSLAPQGGFDKNGNTPHGKGVMKTLTTGSLIARASGL
LHERLDEYELQGPALTTFNFDRNKILAFRQLAAENKYGLMDTMRVGKQLKDVKTMSDL
KQALKNIAIKKCQIVYNGSTYTLEADGKGSVKVDKVQSATVQTNNELAGALHHLRCAR
IRYYVKCAQEALYSIIQIAGAAFVTTRIAKRMNIQNLWSKPQVEDTEEMTNKDGCLKP
KDDEEFVVSSDDIKTEGKKGKNKSGRGKKHTAFSSKGLSDEEYDEYKRIREERNGKYS
IEEYLQDRDRYYEEVAIARATEEDFCEEEEAKIRQRIFRPTRKQRKEERASLGLVTGS
EIRKRNPEDFKPKGKLWADDDRSVDYNEKLNFEAPPSIWSRIVNFGSGWGFWVSPSLF
ITSTHVIPQGAKEFFGVPIKQIQIHKSGEFCRLRFPKPIRTDVTGMILEEGAPEGTVV
TLLIKRPTGELMPLAARMGTHATMKIQGRTVGGQMGMLLTGSNAKSMDLGTTPGDCGC
PYIYKRGNDYVVIGVHTAAARGGNTVICATQGSEGEATLEGGDNKGTYCGAPILGPGS
APKLSTKTKFWRSSTTPLPPGTYEPAYLGGKDPRVKGGPSLQQVMRDQLKPFTEPRGK
PPRPNVLEAAKKTIINVLEQTIDPPQKWSFAQACASLDKTTSSGHPHHMRKNDCWNGE
SFTGKLADQASKANLMFEEGKNMTPVYTGALKDELVKTDKVYGKIKKRLLWGSDLATM
IRCARAFGGLMDELKAHCVTLPVRVGMNMNEDGPIIFEKHSRYRYHYDADYSRWDSTQ
QRDVLAAALEIMVKFSPEPHLAQVVAEDLLSPSVMDVGDFQISISEGLPSGVPCTSQW
NSIAHWLLTLCALSEVTDLSPDIIQANSLFSFYGDDEIVSTDIKLDPEKLTTKLKEYG
LKPTRPDKTEGPLVISEDLDGLTFLRRTVTRDPAGWFGKLEQSSILRQMYWTRGPNHE
DPFETMIPHSQRPIQLMSLLGEAALHGPAFYSKISKLVIAELKEGGMDFYVPRQEPMF
RWMRFSDLSTWEGDRNLAPSFVNEDGVE"
mat_peptide <1..982
/gene="ORF1"
/product="p48"
mat_peptide 983..2080
/gene="ORF1"
/product="NTPase"
mat_peptide 2081..2617
/gene="ORF1"
/product="p22"
mat_peptide 2618..3016
/gene="ORF1"
/product="VPg"
mat_peptide 3017..3559
/gene="ORF1"
/product="Pro"
mat_peptide 3560..5089
/gene="ORF1"
/product="RdRp"
gene 5073..6695
/gene="ORF2"
CDS 5073..6695
/gene="ORF2"
/note="major capsid protein"
/codon_start=1
/product="VP1"
/protein_id="QNS37118.1"
/translation="MKMASSDANPSDGSAANLVPEVNNEVMALEPVVGAAIAAPVAGQ
QNVIDPWIRNNFVQAPGGEFTVSPRNAPGEILWSAPLGPDLNPYLSHLARMYNGYAGG
FEVQVILAGNAFTAGKVIFAAVPPNFPTEGLSPSQVTMFPHIVVDVRQLEPVLIPLPD
VRNNFYHYNQSNDPTIKLIAMLYTPLRANNAGDDVFTVSCRVLTRPSPDFDFIFLVPP
TVESRTKPFSVPVLTVEEMTNSRFPIPLERLFTGPSSAFVVQPQNGRCTTDGVLLGTT
QLSPVNICTFRGDVTHITGSHNYTMNLASQNWNNYDPTEEIPAPLGTPDFVGKIQGVL
TQTTRTDGSTRGHKATVYTGSAEFAPKLGRVQFETDTNHDFEANQNTKFTPVGVIQDG
STTHRNEPLQWVLPSYSGRNTHNVHLAPAVAPTFPGEQLLFFRSTMPGCSGYPNMDLD
CLLPQEWVQYFYQEAAPAQSDVALLRFVNPDTGRVLFECKLHKSGYITVAHTGQHDLV
IPPNGYFRFDSWVNQFYTLAPMGNGTGRRRAV"
gene 6695..7501
/gene="ORF3"
CDS 6695..7501
/gene="ORF3"
/note="minor structural protein; small basic protein"
/codon_start=1
/product="VP2"
/protein_id="QNS37119.1"
/translation="MAGAFFAGLASDVLGSGLGSLINAGAGAINQKVEFENNRKLQQA
SFQFSSNLQQASFQHDKEMLQAQIEATKKLQQEMMKVKQAMLLEGGFSETDAARGAIN
APMTKALDWSGTRYWAPDARTTTYNAGRFSTPQPSGTLPGRANLRDAVPVRGSSSKSS
NSSTATTVYSNQTTSTRLGSTAGSGTSVSSLPSTARTRSWVEDQSRNLSPFMRGAHNI
SFVTPPSSRSSSQGTVSTVPKEVLDSWTGAFNTRRQPLFAHIRKRGESRA"
ORIGIN
1 tgcgtctaac gacgcttccg ctgccgctgt tgccaacagc aacaacgaca tcgcaaaatc
61 ttcaagtgac ggtgtgtttt ctaacatggc tgtcactttt aagcgggccc tcggggcgcg
121 gcctaagcag ccgcccccga aggagatact acccagaccc ccgcgaccac ccacaccaga
181 attggtcaaa aagatccctc ctcccccacc caacggggag gatgaactag tggtctctta
241 tagcgccaaa gatggcgttt ccggactgcc tgagctcacc actgttagac aaccggaaga
301 aaccaacacg gcgttcagtg tccccccact caaccaaagg gagagcaggg acgccaagga
361 gccactaact ggaacaatta ttgaaatgtg ggatggagaa atttaccatt acggcctgta
421 cgtggagcga ggtcttatac ttggtgtgca caagccaccg gcagccatca gccttgccaa
481 ggttgagcta acaccgctct ctttgttctg gagacctgta tacacccccc agtatctcat
541 ctctccagac actcttagga gattacatgg agagtcattc ccttacactg catttgacaa
601 caattgctac gccttttgtt gttgggtgtt agacctaaac gactcatggc taagcaggag
661 aatgattcag agaacaacag gtttcttcag gccgtaccag gattggaaca ggaagcccct
721 ccccactatg gatgattcca aattaaagaa ggtagccaac atattcttgt gcactttgtc
781 ttcactattc accagaccca ttaaggacat aatagggaag ttgaaacctc ttaacatcct
841 caacattctg gctacatgtg actggacctt cgcaggcata gtggaatctt taatactctt
901 agcagaactc tttggagttt tctggacacc cccagatgtg tctgcgatga tcgccccctt
961 gctaggtgat tatgaactgc aaggacctga ggaccttgca gtggaactgg tcccaatagt
1021 gatggggggg ataggtttgg tgctaggatt taccaaagag aaaattggaa agatgctatc
1081 atccgctgca tccactttaa gagcttgtaa agaccttggt gcatacggac tggaaatctt
1141 aaaattggtc atgaagtggt tcttcccaaa gaaagaggaa gcaaatgaac tggctatggt
1201 gagatccatc gaggatgcag tgctagacct cgaggcaatt gaaaacaacc acatgaccac
1261 cctactcaaa gacaaagaca gcttggcaac ctatatgaga acccttgacc ttgaggagga
1321 gaaagccagg aaactctcaa ccaaatctgc ttcacccgat attgtgggca caatcaactc
1381 tcttctggca agaatcgctg ctgcacgctc cctagtgcat cgggcgaaag aagagctctc
1441 cagcaggccg agacctgtcg ttgtgatgat atcgggaaga ccagggatag ggaagactca
1501 ccttgccagg gaactggcca agaagatcgc ggcctccctc acaggggacc agcgtgtggg
1561 tcttatccca cgcaatggtg tcgatcactg ggacgcatac aagggcgaaa gagttgtcct
1621 atgggacgac tatggaatga gcaaccccat ccatgacgcc ctcaggttgc aggagcttgc
1681 tgacacttgc cctctcacgc tgaattgtga cagaattgag aacaaaggga aagtctttga
1741 cagtgatgcc ataattatca ccaccaatct ggccaaccca gcaccactgg attatgtcaa
1801 ctttgaagcg tgctcgagac gtattgactt cctcgtgtac gcagaagccc ctgaggtgga
1861 gaaggcaaag cgcgacttcc caggtcaacc tgacatgtgg aagaacgctt tcagtcctga
1921 cttctcacac ataaaactgt cattggctcc acagggtggt tttgacaaga acggcaacac
1981 cccgcatgga aaaggggtca tgaagaccct caccactggc tccctcatcg cccgagcatc
2041 agggttgctc catgagaggc tggacgaata tgaactgcaa ggcccagccc tcaccacttt
2101 caactttgac cgcaacaaga tacttgcttt taggcagctc gctgctgaaa acaagtatgg
2161 gctgatggac acaatgagag ttggaaaaca gctcaaggat gtcaagacca tgtcagacct
2221 caaacaagca ctcaagaaca tcgcgatcaa gaagtgccag atagtgtaca atggtagcac
2281 ctacacactt gaggccgatg gcaagggtag tgtgaaagtt gacaaagtgc aaagtgccac
2341 tgtgcagacc aacaatgaac tagccggtgc cctacaccac ctaaggtgcg ctagaatcag
2401 atactatgtc aagtgcgccc aggaggcact gtactccatc atccaaatcg ctggggctgc
2461 attcgtcacc acgcgcatcg ctaagcgcat gaatatacag aatctctggt ccaagccaca
2521 ggtggaagac acagaagaga tgaccaacaa agatggttgc ctaaaaccca aagatgatga
2581 agagtttgtc gtctcatctg atgacatcaa aactgagggc aagaaaggga agaataagtc
2641 cggccgtggt aagaagcaca cagccttttc aagcaaagga ctcagtgatg aggagtacga
2701 tgagtacaag agaatcagag aagaaaggaa tggtaagtac tccatagaag agtaccttca
2761 ggacagagac aggtactacg aggaggtggc cattgccagg gcaaccgaag aggacttctg
2821 tgaagaagaa gaggccaaaa tccggcagag aattttcaga ccaacaagga aacaacgcaa
2881 agaggagagg gcctctctcg gcttggtcac aggctctgaa atcaggaaga gaaacccaga
2941 agacttcaaa cccaagggaa agctgtgggc tgatgatgac agaagtgttg attacaatga
3001 gaaactcaac tttgaggccc caccaagcat ttggtcgcgg atagtcaact ttggttcagg
3061 ctggggcttc tgggtctccc ccagtctgtt tataacatca acccatgtca taccccaagg
3121 tgcaaaagag ttcttcggag tccctatcaa gcagatccag atacacaaat caggtgagtt
3181 ctgccggttg agattcccaa aaccaatcag aactgacgtg acgggcatga ttctagaaga
3241 aggtgcgccc gagggaaccg tggtcacact gctcatcaag agaccaactg gagaactcat
3301 gcctctggca gctagaatgg ggacccatgc aaccatgaaa attcaggggc gcacagtcgg
3361 agggcaaatg ggtatgctcc tgacaggatc caacgccaag agtatggacc taggcacaac
3421 accaggcgac tgcggctgtc cctacatcta caagaggggg aatgactacg tggtcatagg
3481 agtccatacg gccgctgccc gtggaggaaa cactgtcata tgtgccaccc aggggagtga
3541 gggagaagcc acacttgaag gaggtgacaa taaagggaca tactgtggcg caccaatctt
3601 gggcccaggg agcgctccga agctcagtac caagaccaaa ttttggagat catccacaac
3661 accactccca cctggcacct acgaaccagc ctacctcggt ggcaaagacc ccagggtcaa
3721 aggtggccct tcattgcaac aagttatgag ggaccagcta aagccattca cagaacccag
3781 aggcaaacca ccaagaccaa atgtgttgga agctgccaag aaaaccatca tcaatgtcct
3841 tgagcaaaca attgatccac cccaaaaatg gtcgtttgcg caagcttgcg catcccttga
3901 caaaaccacc tccagcggcc acccacacca catgcggaaa aacgattgtt ggaatgggga
3961 gtccttcaca ggaaaattgg ctgatcaagc ctccaaggcc aacctaatgt ttgaagaggg
4021 aaagaacatg actccagtct acacaggtgc acttaaagat gagttggtaa agaccgataa
4081 agtttatggt aagatcaaga agaggcttct gtggggttca gatctggcga ccatgatacg
4141 gtgcgcccga gcttttggag gccttatgga tgaactcaag gcgcactgtg tcacgcttcc
4201 tgtcagagtt ggtatgaaca tgaatgagga tggccccatc atctttgaga agcactccag
4261 atatagatat cactatgatg ctgattattc ccggtgggac tcaacacaac aaagggatgt
4321 gctagcagca gcactagaaa tcatggtcaa gttctctcca gaaccacacc tggcccaggt
4381 agttgcagaa gacctccttt cccctagcgt aatggatgta ggtgactttc aaatatcaat
4441 aagtgagggt cttccctctg gggtaccttg cacctcccag tggaattcca tcgcccactg
4501 gctcctcact ctttgtgcac tctctgaagt cacggacctg tcccctgaca tcatccaggc
4561 caactccctt ttctccttct atggtgatga tgagattgtg agcacagata taaagttgga
4621 cccagagaaa ctgacaacaa aactcaagga gtacgggctg aaaccaaccc gccccgacaa
4681 aactgagggg ccccttgtta tctctgaaga cctggatggc ctgacattcc tccggagaac
4741 tgtgacccgt gacccagctg gctggtttgg aaaattggaa caaagttcaa ttctcagaca
4801 aatgtactgg accaggggtc ccaaccatga agatccattt gaaacaatga taccacactc
4861 ccaaagaccc atacaattga tgtccttgct gggcgaggct gcactccacg gcccggcatt
4921 ttatagcaag attagcaaat tagtcattgc agagttgaag gaaggtggca tggattttta
4981 cgtgcccaga caagagccaa tgttcagatg gatgagattc tcagatctga gcacgtggga
5041 gggcgatcgc aatctggctc ccagttttgt gaatgaagat ggcgtcgagt gacgccaacc
5101 catctgatgg gtccgcagcc aacctcgttc cagaggtcaa caatgaggtt atggctctgg
5161 agcccgttgt tggtgccgct attgcggcac ctgtagcggg ccaacaaaat gtaattgacc
5221 cctggattag aaacaatttt gtacaagccc ctggtggaga gtttacagta tcccctagaa
5281 acgctccagg tgaaatacta tggagcgcgc ccttgggacc tgatctaaat ccctacctat
5341 cccatttggc cagaatgtac aatggttatg caggtggttt tgaagtgcag gtaattctcg
5401 cggggaacgc gttcaccgcc gggaaggtca tatttgcagc agtcccacca aattttccaa
5461 ctgaaggctt gagccccagc caggtcacta tgttccccca tatagtagtg gatgttaggc
5521 aactagaacc tgtgttgatt cccttacccg atgttaggaa taatttctat cattataatc
5581 aatcaaatga ccccaccatt aagttgatag caatgttgta tactccactc agggctaata
5641 atgctgggga tgatgtcttc acagtttctt gccgagttct cacgagacca tcccccgatt
5701 ttgatttcat atttctagtg ccacccacag ttgagtcaag aactaaacca ttctctgtcc
5761 cagttttaac tgttgaggag atgaccaatt caagattccc cattcctttg gaaaggctgt
5821 tcacgggtcc cagcagtgcc tttgttgttc aaccacaaaa cggcaggtgc acgactgatg
5881 gcgtgctcct aggcaccacc caactgtctc ctgtcaacat ctgcaccttc agaggagatg
5941 tcacccacat cacaggtagt cataactaca caatgaattt ggcttctcaa aattggaaca
6001 attatgaccc aacagaagaa atcccagccc ccctaggaac tccagacttt gtggggaaga
6061 ttcaaggcgt gctcacccaa accacaagga cagatggctc aacacgcggc cacaaagcca
6121 cagtgtacac tgggagcgcc gaatttgctc caaaactggg tagagttcaa tttgaaactg
6181 acacaaacca tgattttgaa gctaaccaaa acacaaaatt caccccagtc ggtgtcatcc
6241 aagatggtag caccacccac cgaaatgaac ccctacaatg ggtgctccca agttactcag
6301 gcagaaatac tcataatgtg catctggccc ccgctgtagc ccccaccttt ccgggtgagc
6361 aacttctctt cttcagatcc accatgcccg gatgcagcgg gtaccccaac atggatttgg
6421 actgtctact cccccaggaa tgggtgcagt acttctacca agaggcagcc ccagcacaat
6481 ctgatgtggc tctgctaaga tttgtgaacc cagacacagg tagggttttg tttgagtgta
6541 agcttcataa atcaggctat attacagtgg ctcacactgg ccaacatgat ttggttattc
6601 cccccaatgg ttattttaga tttgactcct gggtcaacca gttctacacg cttgccccca
6661 tgggaaatgg aacggggcgt agacgtgcag tataatggct ggagctttct ttgctggatt
6721 ggcatctgat gtccttggct ctggacttgg ttcccttatc aatgctgggg ctggggccat
6781 caaccaaaaa gttgagtttg aaaacaacag aaaattgcag caagcatcct tccaatttag
6841 cagcaatcta caacaggctt cctttcaaca tgacaaagag atgctccaag cacaaattga
6901 ggccaccaaa aagttacaac aggaaatgat gaaagtcaag caggcaatgc tcctagaggg
6961 tgggttctct gagacggatg cagcccgcgg ggcaatcaac gcccccatga caaaagcttt
7021 ggactggagc gggacaaggt actgggctcc cgatgctagg accacaacat acaatgcagg
7081 ccgcttctcc acccctcaac catcggggac actgccagga agagctaatc ttagggatgc
7141 tgtccctgtt cggggttcct ccagtaaatc ttctaactcc tctactgcta ctactgtgta
7201 ttcaaatcaa actacttcaa cgagacttgg ttctacagct ggttctggta ccagtgtctc
7261 gagcctcccg tcaactgcaa ggactaggag ctgggttgag gatcagagta ggaatttgtc
7321 acctttcatg aggggggcac acaacatatc gtttgtcacc ccaccatcta gcagatcctc
7381 tagccaaggc acagtctcaa ccgtgcctaa agaggttttg gactcctgga ctggcgcttt
7441 caacacgcgc aggcagccac tcttcgctca cattcgtaag cgaggggagt cacgggcgta
7501 atgtgaaaag acaaaattga ttatctttct ttttctttag tgtct
//