Typing tool
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Typing tool
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Complete norovirus genomes
| MW009070 | GII.4 Sydney | |
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| GII.P4 New Orleans |
ORF1: 1..5094
ORF2: 5075..6697
ORF3: 6697..7500
LOCUS MW009070 7561 bp RNA linear VRL 21-SEP-2020
DEFINITION Norovirus GII isolate 432-2 nonstructural polyprotein (ORF1) gene,
partial cds; and VP1 (ORF2) and VP2 (ORF3) genes, complete cds.
ACCESSION MW009070
VERSION MW009070.1
DBLINK BioProject: PRJNA604000
KEYWORDS .
SOURCE Norovirus GII
ORGANISM Norovirus GII
Viruses; Riboviria; Orthornavirae; Pisuviricota; Pisoniviricetes;
Picornavirales; Caliciviridae; Norovirus; Norovirus norwalkense.
REFERENCE 1 (bases 1 to 7561)
AUTHORS Yang,Z., Silva,A.J., Wolfe,J., Hirneisen,K., Ruelle,S., Torres,A.,
Williams-Hill,D., Kulka,M. and Hellberg,R.S.
TITLE Direct Submission
JOURNAL Submitted (15-SEP-2020) Molecular Virology Team/Devision of
Molecular Biology, OARSA/CFSAN/FDA, 8301 Muirkirk Rd., Laurel, MD
20708, USA
COMMENT ##Assembly-Data-START##
Assembly Method :: CLC GWB v. 11
Sequencing Technology :: Illumina
##Assembly-Data-END##
FEATURES Location/Qualifiers
source 1..7561
/organism="Norovirus GII"
/mol_type="genomic RNA"
/isolate="432-2"
/isolation_source="stool"
/host="Homo sapiens"
/db_xref="taxon:122929"
/geo_loc_name="USA"
/collection_date="10-Apr-2017"
/note="genotype: GII.P4-GII.4"
gene <1..5094
/gene="ORF1"
CDS <1..5094
/gene="ORF1"
/codon_start=1
/product="nonstructural polyprotein"
/protein_id="QNS37114.1"
/translation="MASNDATAAAVANSNNDTAKSSSDGVLSSMAVTFKRALGARPKQ
PPPREKPQRPPRPPTPELVKNIPPPPPNGEDEIVVTYSVKDGVSGLPDLSTVRQPEES
NTAFSVPPLNQRENRDAKEPLTGTILEMWDGEIYHYGLYVERGLVLGVHKPPAAISLA
KVELAPLSLYWRPVYTPQYLISPDTLKKLSGETFPYTAFDNNCYAFCCWVLDLNDSWL
SRRMIQRTTGFFRPYQDWNRKPLPTMDDSKIKKVANIFLCALSSLFTRPIKDIIGKIR
PLNILNILASCDWTFAGIVESLILLAELFGVFWTPPDVSAMIAPLLGDYELQGPEDLA
VELVPVVMGGIGLVLGFTKEKIGKMLSSAASTLRACKDLGAYGLEILKLVMKWFFPKK
EEANELAMVRSIEDAVLDLEAIENNHMTTLLKDKDSLATYMRTLDLEEEKARKLSTKS
ASPDIVGTINALLARIAAARSLVHRAKEELSSRPRPVVLMISGRPGIGKTHLAREVAK
RIAASLTGDQRVGLIPRNGVDHWDAYKGERVVLWDDYGMSNPIHDALRLQELADTCPL
TLNCDRIENKGKVFDSDVIIITTNLANPAPLDYVNFEACSRRIDFLVYAEAPDVEKAK
RDFPGQPDMWKNAFSSDFSHIKLALAPQGGFDKNGNTPHGKGVMKTLTTGSLIARASG
LLHERLDEFELQGPALTTFNFDRNKVLAFRQLAAENKYGLMDTMRVGKQLKDVKTMPE
LKQALKNVSIKKCQIVYNGCTYMLESDGKGNVKVDRIQSAAVQTNNELAGALHHLRCA
RIRYYVKCVQEALYSIIQIAGAAFVTTRIAKRMNIQDLWSKPQVENTEETTSKDGCPK
PKDDEEFVISSDDIKTEGKKGKNKTGRGKKHTAFSSKGLSDEEYDEYKRIREERNGKY
SIEEYLQDRDKYYEEVAIARATEEDFCEEEEAKIRQRIFRPTRKQRKEERVSLGLVTG
SEIRKRNPDDFKPKGKLWADDDRSVDYNEKLSFEAPPSIWSRIVNFGSGWGFWVSPSL
FITSTHVIPQGAKEFFGVPIKQIQVHKSGEFCRLRFPKPIRTDVTGMILEEGAPEGTV
VTLLIKRSTGELMPLAARMGTHATMKIQGRTVGGQMGMLLTGSNAKSMDLGTTPGDCG
CPYIYKRGNDYVVIGVHTAAARGGNTVICATQGSEGEATLEGGDNKGTYCGAPILGPG
SAPTLSTKTKFWRSSTASLPPGTYEPAYLGGKDPRVKGGPSLQQVMREQLKPFTEPRG
KPPKPSVLEAAKKTIINVLEQTIDPPERWSFAQACASLDKTTSSGHPHHMRKNDCWNG
ESFTGKLADQASKANLMFEEGKNMTPVYTAALKDELVKTDKIYGKIKKRLLWGSDLAT
MIRCARAFGGLMDELKAHCVTLPVRVGMNMNEDGPIIFERHSRYTYHYDADYSRWDST
QQRAVLAAALEIMVKFSPEPHLAQVVAEDLLSPSVVDVGDFTISINEGLPSGVPCTSQ
WNSIAHWLLTLCALSEVTNLSPDTIQANSLFSFYGDDEIVSTDIKLDPEKLTAKLKEY
GLKPTRPDKTEGPLVISEDLNGLTFLRRTVTRDPAGWFGKLEQSSILRQMYWTRGPNH
GDPSETMIPHSQRPIQLMSLLGEAALHGPAFYSKISKLVIAELKEGGMDFYVPRQEPM
FRWMRFSDLSTWEGDRNLAPSFVNEDGVE"
mat_peptide <1..984
/gene="ORF1"
/product="p48"
mat_peptide 985..2082
/gene="ORF1"
/product="NTPase"
mat_peptide 2083..2619
/gene="ORF1"
/product="p22"
mat_peptide 2620..3018
/gene="ORF1"
/product="VPg"
mat_peptide 3019..3561
/gene="ORF1"
/product="Pro"
mat_peptide 3562..5091
/gene="ORF1"
/product="RdRp"
gene 5075..6697
/gene="ORF2"
CDS 5075..6697
/gene="ORF2"
/note="major capsid protein"
/codon_start=1
/product="VP1"
/protein_id="QNS37115.1"
/translation="MKMASSDANPSDGSAANLVPEVNNEVMALEPVVGAAIAAPVAGQ
QNVIDPWIRNNFVQAPGGEFTVSPRNAPGEILWSAPLGPDLNPYLSHLARMYNGYAGG
FEVQVILAGNAFTAGKVIFAAVPPNFPTEGLSPSQVTMFPHIVVDVRQLEPVLIPLPD
VRNNFYHYNQSNDPTIKLIAMLYTPLRANNAGDDVFTVSCRVLTRPSPDFDFIFLVPP
TVESRTKPFSVPVLTVEEMTNSRFPIPLEKLFTGPSSAFVVQPQNGRCTTDGVLLGTT
QLSPVNICTFRGDVTHITGSRNYTMNLASQNWNNYDPTEEIPAPLGAPDFVGKIQGML
TQTTRADGSTRGHKATVYTGSADFAPKLGRVQFETDTDHDFEANQNTKFTPVGVIQDG
STTHRNEPQQWVLPSYSGRNTHNVHLAPAVAPTFPGEQLLFFRSTMPGCSGYPNMDLD
CLLPQEWVQYFYQEAAPAQSDVALLRFVNPDTGRVLFECKLHKSGYVTVAHTGQHDLV
IPPNGYFRFDSWVNQFYTLAPMGNGTGRRRVV"
gene 6697..7500
/gene="ORF3"
CDS 6697..7500
/gene="ORF3"
/note="minor structural protein; small basic protein"
/codon_start=1
/product="VP2"
/protein_id="QNS37116.1"
/translation="MAGAFFAGLASDVLGSGLGSLINAGAGAINQKVEFENNRKLQQA
SFQFSSNLQQASFQHDKEMLQAQIEATKKLQQEMMKVKQAMLLEGGFSETDAARGAIN
APMTKALDWSGTRYWAPDARTTTYNAGRFSTPQPSGVLPGRTNLRDAVPARGSSKSSN
SSTATSVYSNQTTSTRLGSTAGSGTSVSSLPSTARTRSWVEDQSRNLSPFMRGAHNIS
FVTPPSSRSSSQGTVSTVPKEVLDSWTGAFNTRRQPLFAHIRKRGESRA"
ORIGIN
1 atggcgtcta acgacgctac cgctgccgct gttgctaaca gcaacaacga caccgcaaaa
61 tcttcaagtg acggagtgct ttctagcatg gctgtcactt ttaaacgagc cctcggggcg
121 cggcctaaac agcccccccc gagggaaaaa ccacaaagac ccccacgacc acccacacca
181 gaactggtta aaaatattcc ccccccccca cccaacggag aggatgaaat agtggttact
241 tatagtgtca aagatggtgt ttccggcttg cctgaccttt ccaccgtcag acagccggaa
301 gaatccaaca cggccttcag tgtccctcca ctcaatcaga gggagaacag agatgctaag
361 gaaccactca ctggaacaat tctggaaatg tgggacgggg aaatctacca ttatggcctg
421 tatgtggagc gaggtcttgt actaggcgta cacaaaccgc cagctgccat cagcctcgct
481 aaggttgagt tggcaccact ctccttatac tggaggcctg tgtacactcc tcagtacctc
541 atctctccag acactctcaa gaaattgtcc ggggaaacgt tcccctacac agcatttgac
601 aacaactgct atgccttttg ttgctgggtt ctggacctaa atgactcgtg gctgagcagg
661 agaatgatcc agaggacaac tggtttcttc aggccctacc aagactggaa taggaaaccc
721 cttcccacta tggatgactc caaaataaag aaggtggcca atatatttct gtgtgccctg
781 tcctcgctat tcaccaggcc cataaaagat ataataggga aaataaggcc tcttaacatc
841 ctcaacatct tggcctcatg tgattggacc tttgcgggca tagtagagtc cctgatactc
901 ttagcagagc tctttggagt tttctggaca cccccagatg tgtctgcaat gattgccccc
961 ttacttggtg actacgagct acaaggacct gaggaccttg cagtggagct cgtccccgtg
1021 gtgatggggg gaattggttt ggtgctagga ttcaccaaag agaaaattgg gaaaatgttg
1081 tcatcagctg cgtccacctt aagagcttgc aaagaccttg gtgcatatgg gctagagatc
1141 ctaaagctag tcatgaagtg gttcttcccg aagaaggagg aggcaaatga gctggctatg
1201 gtgaggtcca tcgaggatgc agtcctggat ctcgaagcaa ttgaaaacaa tcatatgacc
1261 accttgctta aagataaaga cagtctggca acctacatga gaacactcga tcttgaagag
1321 gagaaagcca ggaaactctc aaccaagtct gcctcacctg acatcgtggg cacaatcaac
1381 gccctcctgg cgagaatcgc tgccgcacgt tctctggtgc atcgagcgaa ggaggagctt
1441 tccagcagac caagacctgt ggtgttgatg atatcaggta ggccaggaat agggaagacc
1501 cacctcgcta gggaagtggc taagagaatc gcagcctccc ttacaggaga ccagcgtgtt
1561 ggtctcatcc cacgcaatgg cgtcgaccac tgggatgcgt ataaggggga gagggtcgtc
1621 ctatgggacg attatggaat gagcaaccct attcacgatg ccctcaggct gcaagaactc
1681 gctgacactt gccccctcac tctgaactgt gacaggattg aaaataaggg aaaggtcttt
1741 gacagcgatg tcatcattat caccactaat ctggccaacc cagccccact ggactatgtc
1801 aactttgaag catgctcgag gcgcattgac ttcctcgtat atgcagaagc ccctgatgtc
1861 gaaaaggcga agcgtgactt cccaggccag cctgacatgt ggaagaacgc tttcagttcc
1921 gatttctcac acataaaact agcactggcc ccacagggtg gtttcgacaa gaacgggaac
1981 accccacacg gaaagggcgt catgaagact ctcaccactg gctcccttat tgcccgggca
2041 tcagggctac tccatgagag gttagatgaa tttgaactgc agggcccagc tctcaccacc
2101 ttcaatttcg atcgcaataa agtgcttgcc tttagacagc ttgctgctga aaacaaatat
2161 ggactgatgg acacaatgag ggttgggaaa cagctcaagg atgtcaaaac catgccagaa
2221 ctcaaacaag cactcaagaa tgtctcaatc aagaagtgtc aaatagtgta taatggttgc
2281 acctacatgc ttgagtctga tggcaagggc aatgtgaaag ttgacaggat ccagagcgcc
2341 gccgtgcaga ccaacaatga gctggctggt gccctgcacc acttgaggtg cgccagaatc
2401 agatactatg tcaagtgtgt ccaggaagcc ctgtattcca tcattcaaat tgctggggct
2461 gcatttgtca ccacgcgcat tgccaagcgc atgaacatac aggatctatg gtccaagcca
2521 caagtggaaa atacagagga aactaccagc aaggacgggt gcccaaaacc caaggatgat
2581 gaggagtttg tcatttcatc cgacgacatc aaaactgagg gcaagaaagg gaagaacaag
2641 actggccgtg gcaagaagca cacagcattt tcaagcaaag gcctcagtga tgaagagtac
2701 gatgaataca agaggatcag agaagaaagg aatggcaagt actctataga agagtacctc
2761 caggacaggg acaaatatta tgaggaggtg gccattgcca gagcgactga ggaagacttc
2821 tgtgaagagg aggaagccaa gatccgacaa aggatcttta ggccaacaag gaaacaacgc
2881 aaggaggaaa gagtctctct cggtttagtc acgggctctg aaattaggaa aagaaaccca
2941 gatgatttca aacccaaagg gaaattgtgg gctgacgatg acaggagtgt ggactacaat
3001 gagaaactca gttttgaggc cccgccaagc atttggtcaa gaatagtcaa ctttggttca
3061 ggctggggat tctgggtctc ccccagcttg ttcataacat caacccatgt tataccccag
3121 ggcgcaaagg agttctttgg agtccccatc aaacaaatac aggtacacaa gtcaggcgag
3181 ttctgtcgct tgagattccc taaaccaatc aggactgatg tgacgggcat gatcttagaa
3241 gaaggcgcac ctgagggcac cgtggttaca ctactcatca aaaggtccac cggggaactt
3301 atgcccctag cagctaggat ggggacccat gcgaccatga agatccaagg gcgcactgtt
3361 gggggccaga tgggcatgct tctgacaggg tccaacgcca agagtatgga cctgggtact
3421 acaccaggtg attgtggctg cccctacatc tacaagagag gtaatgacta tgtggtcatt
3481 ggagtccaca cggccgccgc acgtgggggg aacactgtca tatgtgccac ccaggggagt
3541 gaaggagagg ctacacttga gggtggtgac aacaagggga cttactgtgg tgcaccaatc
3601 ctaggcccag ggagtgcccc aacacttagc accaagacca aattctggag atcgtccaca
3661 gcatcactcc cacctggcac ctatgaacca gcctatcttg gtggcaagga ccctagagtc
3721 aagggtggcc cttcactaca gcaagtcatg agggaacagt tgaagccatt cacagagccc
3781 agaggtaagc caccaaaacc aagtgtgtta gaagctgcca agaaaaccat catcaatgtt
3841 cttgagcaaa caattgatcc acctgagaga tggtcgttcg cacaagcttg cgcgtctctt
3901 gacaagacca cttccagtgg tcatccgcat cacatgcgga aaaacgactg ctggaacggg
3961 gagtccttca caggcaagct ggcagaccag gcttctaagg ccaacctgat gtttgaagaa
4021 ggaaagaaca tgaccccagt ctacacagct gcgctcaagg atgagctagt taaaactgac
4081 aaaatttatg gtaagatcaa gaagaggctt ctttggggct cggacttggc gaccatgatc
4141 cggtgtgctc gggcattcgg aggcctaatg gatgaactca aagcacactg tgtcacactt
4201 cccgttagag ttggcatgaa tatgaatgag gatggcccca tcatcttcga gaggcattcc
4261 aggtacacgt accactatga tgctgattac tctcgatggg attcaacaca acagagagcc
4321 gtgttggcgg cagctctaga aatcatggta aagttctccc cagaaccaca tttggcccag
4381 gtagtcgctg aagaccttct ttctcctagc gtggtggacg tgggcgactt cacaatatca
4441 atcaacgagg gtcttccctc tggggtgccc tgcacctccc aatggaactc catcgcccac
4501 tggcttctca ctctctgcgc gctctccgaa gtcacaaacc tgtctcctga caccatacag
4561 gctaattctc tcttttcttt ttatggtgat gatgaaattg ttagcacaga cataaaattg
4621 gacccagaga aattgacagc aaaactcaaa gaatacgggt taaaaccaac ccgccctgac
4681 aaaactgaag gaccccttgt catctctgaa gacctgaatg gcctaacttt cctgcggaga
4741 actgtgaccc gcgacccagc tggttggttt ggaaaactgg agcagagttc aatactcagg
4801 caaatgtact ggactagggg tcccaaccat ggagacccat ctgaaacaat gattccacat
4861 tcccaaagac ccatacaatt gatgtcccta ctgggggagg ccgctctcca cggcccagca
4921 ttttacagta agattagcaa attggtcatt gcagagctaa aagaaggtgg tatggatttt
4981 tacgtgccca gacaagagcc aatgttcaga tggatgagat tctcagatct gagcacgtgg
5041 gagggcgatc gcaatctggc tcccagtttt gtgaatgaag atggcgtcga gtgacgccaa
5101 cccatctgat gggtccgcag ccaacctcgt cccagaggtc aacaatgagg ttatggctct
5161 ggagcccgtt gttggtgccg ctattgcggc acctgtagcg ggccaacaaa atgtaattga
5221 cccctggatt agaaacaatt ttgtacaagc ccctggtgga gagtttacag tgtcccccag
5281 aaacgctcca ggtgaaatac tatggagcgc gcccttaggc cctgatttaa atccctacct
5341 atcccacttg gccagaatgt ataatggtta tgcaggtggt tttgaagtgc aggtgattct
5401 cgcggggaac gcgttcaccg ccgggaaggt catatttgca gcagtcccac caaattttcc
5461 aactgaaggc ttgagcccca gccaggtcac tatgttcccc catatagtag tggatgttag
5521 gcaactagaa cctgtgttga ttcccttacc cgatgttagg aataatttct accattacaa
5581 tcaatcaaat gaccccacca ttaagttgat agcaatgtta tatacaccac ttagggctaa
5641 taatgctggg gatgatgtct tcacagtttc ttgccgagtt ctcacgaggc catcccccga
5701 ttttgatttc atatttctag tgccacccac agttgagtct agaaccaaac cattttccgt
5761 cccagttttg actgttgagg agatgaccaa ttcaagattc cccattcctt tggaaaagtt
5821 gttcacgggc cccagtagtg cctttgttgt tcaaccacaa aacggtaggt gcacgactga
5881 tggcgtgctc ctaggcacca cccaattgtc tcctgtcaac atctgcacct tcagagggga
5941 tgtcacccac attacaggta gtcgtaacta cacaatgaat ttggcttctc aaaattggaa
6001 caattatgac ccaacagaag aaatcccagc ccctctagga gctccagatt ttgtggggaa
6061 gattcaaggc atgctcaccc aaaccacaag ggcagatggc tcaacacgcg gccacaaggc
6121 tacggtgtac actgggagcg ccgacttcgc tccaaaactg ggcagagttc aatttgaaac
6181 tgacacagac catgattttg aagctaacca aaacacaaag ttcactccag tcggtgtcat
6241 ccaagatggc agcaccaccc accgaaatga accccaacag tgggtgctcc caagttactc
6301 aggcagaaat actcataatg ttcatctggc ccccgctgtg gcccccactt ttccgggtga
6361 acaacttctc ttctttagat ccaccatgcc cggatgtagc gggtatccca acatggattt
6421 ggactgtttg ctcccccagg aatgggtgca gtacttctac caagaggcag ccccagcaca
6481 atctgatgtg gccctgctaa gatttgtgaa tccagacaca ggtagggttt tgtttgaatg
6541 caaacttcat aaatcaggct atgttacagt ggctcacact ggccaacatg atttggtcat
6601 cccccccaat ggttatttta ggtttgattc ctgggtcaac cagttctaca cgcttgcccc
6661 catgggaaat ggaacggggc gtagacgcgt agtataatgg ctggagcttt ctttgctggg
6721 ttagcatctg atgtcctcgg ctctggactt ggttccctta tcaatgctgg ggctggggcc
6781 atcaaccaaa aagttgagtt tgaaaataac agaaaattgc aacaagcatc cttccaattt
6841 agcagcaatt tacaacaggc ttcctttcaa catgacaaag aaatgcttca agcacaaatt
6901 gaggccacta aaaagctaca acaggaaatg atgaaagtta agcaggcaat gctcctagag
6961 ggtgggttct ctgaaacaga tgcagcccgc ggggcaatca acgcccccat gacaaaagct
7021 ttggactgga gcgggacaag gtactgggct cctgatgcta ggactacaac ttataatgca
7081 ggccgctttt ccacccctca accatcgggg gtactaccag gaaggactaa tcttagggat
7141 gctgtccctg ctcggggttc ctctaaatct tctaactctt ctactgctac ttctgtgtac
7201 tcaaatcaaa ccacttcaac gagacttggt tctacagctg gttctggcac cagtgtctcg
7261 agtctcccgt caactgcaag gaccaggagc tgggttgagg atcaaagtag gaatttgtct
7321 cctttcatga ggggggccca caacatatcg tttgtcaccc caccatctag cagatcctct
7381 agccaaggca cagtctcaac cgtgcctaaa gaggttttgg actcctggac tggcgccttc
7441 aacacgcgca ggcagcctct cttcgctcac attcgtaaac gaggggagtc acgggcgtaa
7501 tgtgaaaaga caaaattgat tatctttctt tttctttagt gtcttttaaa aaaaaaaaaa
7561 a
//