Typing tool
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Typing tool
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Complete norovirus genomes
| MW009069 | GII.5 | |
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| GII.P40 |
ORF1: 1..5128
ORF2: 5109..6731
ORF3: 6731..7507
LOCUS MW009069 7526 bp RNA linear VRL 21-SEP-2020
DEFINITION Norovirus GII isolate 387-2 nonstructural polyprotein (ORF1) gene,
partial cds; and VP1 (ORF2) and VP2 (ORF3) genes, complete cds.
ACCESSION MW009069
VERSION MW009069.1
DBLINK BioProject: PRJNA604000
KEYWORDS .
SOURCE Norovirus GII
ORGANISM Norovirus GII
Viruses; Riboviria; Orthornavirae; Pisuviricota; Pisoniviricetes;
Picornavirales; Caliciviridae; Norovirus; Norwalk virus.
REFERENCE 1 (bases 1 to 7526)
AUTHORS Yang,Z., Silva,A.J., Wolfe,J., Hirneisen,K., Ruelle,S., Torres,A.,
Williams-Hill,D., Kulka,M. and Hellberg,R.S.
TITLE Direct Submission
JOURNAL Submitted (15-SEP-2020) Molecular Virology Team/Devision of
Molecular Biology, OARSA/CFSAN/FDA, 8301 Muirkirk Rd., Laurel, MD
20708, USA
COMMENT ##Assembly-Data-START##
Assembly Method :: CLC GWB v. 11
Sequencing Technology :: Illumina
##Assembly-Data-END##
FEATURES Location/Qualifiers
source 1..7526
/organism="Norovirus GII"
/mol_type="genomic RNA"
/isolate="387-2"
/isolation_source="stool"
/host="Homo sapiens"
/db_xref="taxon:122929"
/country="USA"
/collection_date="14-Nov-2018"
/note="genotype: GII.P40-GII.5"
gene <1..5128
/gene="ORF1"
CDS <1..5128
/gene="ORF1"
/codon_start=2
/product="nonstructural polyprotein"
/protein_id="QNS37113.1"
/translation="ASNDAATATAGNTSTNSVIHNQDVNSTSSLFANMTVGLKRALGA
RPKQPAPRIPSPNREGRHETTPRAPPPNKGGNANIPPIPPPPPNGEDIVIKYTKQDDA
VEGVPTVATVDVPPTHSTAYSVPPLDQREKIEAKEPLTGSILEMWDGEIYHYGLYVEK
GLVLGVHKPPAAISFARIELTPLSLYWRTVYTPPYLIAPETLRKLHGESFPYTAFDNN
CYSFCCWVLDLNDSWLNRKFVSRTTGFYRPYQEWNRKPLPTMDEGKLKKVANVLLCGL
SGLFTRPIKDLIGKLRPLNILNIITNCDWTFPGIVEAFILLAELFGVFWTPPDISTFI
ASLLGDYEMQGPEDIAVEVVPVILGGIGMVLGFTKERIGRLLSSAASSLRACREIGNY
GIEVVKLVMKWFFPTKDETNEMDMVRAIEDAVLDFEAIQNNHMTALLKDKNSLATFLR
ELDMEEEKARKLSTKSASPDIIGTINALLARIAAARSLVHKAKEEMSSRMRPVVIMIS
GRPGIGKTHLARDLAKKMAATLSGDQRVGLVPRNGVDHWDAYKGERIVLWDDYGMSNP
VTDALRLQELADTCPLTLNCDRIENKGKVFDSDTIIITTNLANPAPLDYVNFEACSRR
IDFLVYADSPSVDKAKRDFPGQPDMWKDAFKPDFSHIKLQLAPQGGFDKNGNTPHGKG
VMKTLTTHSLIARATGLLHERLDEFDLQGPELPVYNFDHNRVAAFRRLAADNKYGLME
TIKVGNKLKSVKTLEQLKDALKDISIMPCRIVYNSMAYDLDSNGSGRVSVKKVVDHKI
QTNNELNSALNNLRGARVRYYVKCVQEMVYSLLQIAGAAFVTSRMTRRLNVSSIWARP
EKQVEATEEPPSPPTEDWTITPANAVQEGKKGKNKSGRGKKHTAFSSKGLSDEEYDEY
KRIREERQGKYSIEEYLQDRDRYYEELAIAKATEENFCEEEEIKIRQRVFRPTRKQRK
EERATLGLVTGSEIRKRNPDDFKPRGKLWADDDRSVNYNEKIDFEAPPSLWSRIVNFG
SGWGFWVSSNLLITSTHVIPPNMTEAFGVPISQIQVHRSGEFCKMRFPKAIRPDVSGM
ILEEGAPEGTVVTILIKRTTGELMPLAARMGTHATMKIQGKMLGGQMGMLLTGSNAKN
MDLGTIPGDCGCPYVYKRGNDWVVIGVHTAAARGGNTVICATQGPDGEATLEGRDNHG
TYCGAPILGPGSAPKLSTKTKFWRSSNAPLPPGTYEPAYLGGKDPRVKGGPSLQQVMR
EQLKPFTAPRGKPPRPAILEAAKETICNVLEQIIDPPQKWSYTQACASLDKTTSSGHP
HHMKKNDNWNGESFTGVLADQASKANLMFEQGKHMQPVYTAALKDELVKTSKIYEKIK
KRLLWGSDLGTMIRCARAFGGLMDEMKANCVNLPIRVGMNMNEDGPIIFEKHSKYKYH
YDADYSRWDSTQQRHILGAALEIMVRFSAEPELAQIVSEDLLAPSVVDVGDFKITINE
GLPSGVPCTSQWNSISHWLITLCAISEISGLSPDVVQTNSCFSFYGDDEIVSTDIKLD
PMKLTNKLKEYGLIPTRPDKTEGPLIIKENLDGLTFLRRDVCRDPAGWYGKLDQSSIM
RQLFWTKGPNHEDPNETMIPHSQRPIQLMSLLGEAALHGPVFYKKVSKLVITELKEGG
MDFYVPRQEPMFRWMRFSDLSTWEGDRNLAPEGVNEDGVE"
mat_peptide <1..1033
/gene="ORF1"
/product="p48"
mat_peptide 1034..2131
/gene="ORF1"
/product="NTPase"
mat_peptide 2132..2668
/gene="ORF1"
/product="p22"
mat_peptide 2669..3052
/gene="ORF1"
/product="VPg"
mat_peptide 3053..3595
/gene="ORF1"
/product="Pro"
mat_peptide 3596..5125
/gene="ORF1"
/product="RdRp"
gene 5109..6731
/gene="ORF2"
CDS 5109..6731
/gene="ORF2"
/note="major capsid protein"
/codon_start=1
/product="VP1"
/protein_id="QNS37111.1"
/translation="MKMASNDATPSNDGAAGLVPESNNEAMALEPVVGASLAAPVTGQ
TNIIDPWIRTNFVQAPNGEFTVSPRNSPGEILVNLELGPELNPYLAHLARMYNGYAGG
MEVQVMLAGNAFTAGKVIFAAVPPYFPVENLSPSQITMFPHVVIDVRTLEPVLLPMPD
VRSTLFHFNQKDEPKMRLVAMLYTPLRSNGSGDDVFTVSCRILTRPSPEFDFTYLVPP
TVESKTKPFTLPVLTLGELSNSRFPLSIDEMVTSPNESIVVQPQNGRVTLDGELLGTT
QLQACNICSIRGKVTGQVPNEQHMWNLEVTNLNGTQFDPTDDVPAPLGVPDFAGEVFG
VLSQRNRGESNPANRAHDAVVATYSDKYTPKLGLVQIGTWNTNDVENQPTKFTPIGLN
EVANGHRFEQWTLPRYSGALTLNMNLAPAVAPLFPGERLLFFRSYVPLKGGFGNPAID
CLVPQEWVQHFYQESAPSLGDVALVRYVNPDTGRVLFEAKLHKGGFLTVSSTSTGPVV
VPANGYFRFDSWVNQFYSLAPMGTGNGRRRFQ"
gene 6731..7507
/gene="ORF3"
CDS 6731..7507
/gene="ORF3"
/note="minor structural protein; small basic protein"
/codon_start=1
/product="VP2"
/protein_id="QNS37112.1"
/translation="MAGAFIAGLAGDVLSNGLGSLINAGANAINQRAEFDFNRQLQQN
SFNHDKEMLNAQIQATKQLQADMIAIKQGVLAAGGFSPTDAARGAVNAPMTQALDWSG
TRYWAPGSMKTTSYSGKFVSMNPVRQVEFPQPKKSAAIPSSASSVSSGRTNSTNSTQS
TVVSTSSVSPSRGSSAPSTLSRATTRTSNWVEEQNRNLEPYMRGALQTTFVTPPSSRA
SSNGTVSTVPKGVLDSWTPAFNTRRQPLFAYLRKKGESQV"
ORIGIN
1 ggcgtctaac gacgctgcca ctgcgaccgc tggcaatacc agcacaaaca gtgtgattca
61 caaccaagat gtaaattcta catctagcct ctttgccaac atgactgttg gcctgaagag
121 ggccctgggg gcgagaccaa agcaacccgc tcccaggatt ccttccccca acagggaggg
181 aagacatgaa accaccccta gagctccccc tccgaacaag gggggtaatg ctaacatccc
241 accaatacca cccccaccgc ccaacgggga ggacatagtc atcaagtaca ccaagcaaga
301 tgacgcggtt gaaggggtgc ccaccgtcgc cacggttgat gttcccccca cacacagcac
361 cgcttacagt gtcccccccc tggatcagag ggaaaagatt gaagcgaagg agcccttgac
421 aggttcgata cttgagatgt gggacggtga gatctaccac tatggtctct acgtggagaa
481 gggcttggtt cttggtgtgc acaaacctcc agctgccata agctttgcac gcatagaact
541 cacccccctc tccctatact ggagaacagt ctacactcca ccttacctga tagccccaga
601 aaccctaagg aagctccacg gggagtcatt cccgtataca gcctttgaca acaattgtta
661 ctccttctgc tgctgggtcc tggacctgaa cgattcttgg ctcaacagaa aatttgtgtc
721 aaggacaacg ggtttctaca gaccctacca agagtggaat agaaagcctt tgccaaccat
781 ggatgaagga aagctcaaga aagtggccaa tgtgcttcta tgtggtctct ctgggctttt
841 cactaggccc atcaaggacc tcatagggaa gttgaggcca ctaaacatac taaacatcat
901 caccaattgc gactggacct tccccggaat tgtggaggct ttcatactgc ttgcagagct
961 ctttggagtt ttctggacac caccagacat ttccaccttc atagcttcac ttctgggtga
1021 ctatgaaatg cagggccctg aggatatcgc ggttgaagtc gtaccggtga tcctcggcgg
1081 cataggtatg gtacttggat tcaccaaaga aagaattggc cggttgctga gctctgccgc
1141 ttcctcactt agagcatgca gggagatcgg caactatggg atagaggtgg tgaagctggt
1201 gatgaaatgg tttttcccca ccaaagatga gacaaatgag atggatatgg tgagggcaat
1261 agaggatgct gttcttgact ttgaagccat acagaacaac cacatgacag cattgcttaa
1321 agacaaaaac agccttgcaa ccttcctcag ggagctagat atggaagagg aaaaggcgcg
1381 gaagctatca acaaaatctg cgtccccaga tattatcggc accataaatg cccttctagc
1441 cagaattgcc gctgctaggt ccctagtcca caaggccaag gaagaaatgt catctaggat
1501 gcgtcctgtt gtcatcatga tctccggccg acccgggata gggaagacgc atctggcccg
1561 cgacctggct aagaagatgg cggcgaccct ctcaggtgat cagagagtgg ggctcgtgcc
1621 gaggaatggt gttgaccatt gggacgcata taaaggagag aggatcgtgc tctgggacga
1681 ttatggaatg agcaaccctg tgactgatgc gctgcggctc caggagcttg ccgacacatg
1741 ccccctaacg ctcaactgtg atagaataga aaacaaggga aaagtgtttg acagtgacac
1801 tataatcatc accactaatt tggccaatcc tgctcctcta gattatgtca actttgaagc
1861 ttgctcccgc cgaatcgact tccttgtcta tgcagactcc ccctcggtgg acaaggcgaa
1921 gagagacttc cctggtcaac cagacatgtg gaaggatgcc tttaaaccgg acttttcaca
1981 cataaaactt cagttggcac cacagggagg ctttgataag aacgggaaca cccctcatgg
2041 gaaaggtgtc atgaaaacgc taaccacaca ctcactcatt gcccgcgcca cgggcctcct
2101 acatgaaaga ttggatgagt ttgacctgca gggtcccgag ttgcccgtgt acaattttga
2161 ccacaacagg gtggctgctt tcaggagact ggcagctgac aacaagtatg ggcttatgga
2221 aaccataaag gtgggcaaca aattgaaaag cgtcaagact ctagaacaac tcaaggacgc
2281 tctaaaagac ataagtatca tgccttgcag aatagtctac aactcgatgg cttacgatct
2341 cgattcgaac ggatcaggga gagtcagtgt caaaaaggtt gtagaccaca agatccagac
2401 caacaacgag ctcaattccg ccctcaacaa tctgcgcggt gccagagtga gatactatgt
2461 taaatgtgtt caagagatgg tgtattccct ccttcaaatt gctggcgcag ccttcgtcac
2521 ttcaagaatg acacggaggt tgaacgtcag cagcatttgg gccagaccag aaaaacaggt
2581 ggaggccact gaggaacccc catctccccc gactgaggac tggactataa ccccagcaaa
2641 tgcagtccag gaaggtaaaa agggcaagaa caagagcggc aggggcaaga aacataccgc
2701 cttctccagt aaaggcctaa gtgatgagga gtatgatgag tataagagaa tcagagaaga
2761 gagacaagga aaatactcca tagaagaata ccttcaggat agggaccggt attatgaaga
2821 attggccata gccaaggcaa cagaggagaa cttctgtgag gaggaagaaa taaaaatcag
2881 acagagggtc ttccgtccga ccaggaaaca acgcaaggaa gagagggcaa ctctaggact
2941 ggtcacaggc agtgaaataa ggaagaggaa cccagatgat ttcaagccaa gaggaaaatt
3001 gtgggctgat gatgaccgca gtgtaaatta caatgagaaa atagattttg aagcgcctcc
3061 cagcctttgg tctcgaatag tcaacttcgg gtcaggttgg ggtttttggg tttcttccaa
3121 cttgctcatc acatcaacac atgtcatccc cccgaacatg actgaggcct tcggtgtacc
3181 aataagccag atacaagtac ataggagtgg agagttctgt aaaatgaggt tccccaaagc
3241 tataagacct gatgtctcag gcatgatcct tgaggaagga gctcccgagg gaacggtggt
3301 gaccatactg atcaagagga ccaccggtga gctcatgcca ctggccgccc gaatgggcac
3361 ccacgccacc atgaaaattc aagggaaaat gcttggaggc caaatgggca tgctcctcac
3421 ggggtccaac gctaagaaca tggacctcgg taccatccct ggagactgtg gttgtcccta
3481 tgtttacaag aggggtaacg actgggtggt tataggggtg cacaccgcag ccgccagagg
3541 tggcaacact gtgatttgtg ccactcaggg tccagacggt gaggccacgc tcgaggggag
3601 agacaaccac gggacctact gtggggcacc aatacttgga ccaggaagtg caccaaaact
3661 cagcactaag actaaattct ggaggtcatc caacgcccca cttccgcctg gcacttatga
3721 gcccgcttac ctaggcggaa aagacccaag agtcaagggg ggaccatcac tacagcaagt
3781 catgagggaa caactcaaac ctttcacagc cccccgaggg aagcccccac gaccggcgat
3841 cctggaggct gctaaggaaa ccatctgtaa tgtacttgaa cagatcattg acccacccca
3901 aaaatggtct tatactcagg cctgtgcctc tctagacaaa acaacatcca gtggccatcc
3961 ccaccacatg aaaaagaatg acaactggaa cggagagtcc tttaccggtg tgttggctga
4021 ccaagcttcc aaggcaaatc tcatgtttga acaagggaaa cacatgcaac ctgtgtatac
4081 tgccgccctc aaagacgagc tcgtcaagac tagcaagatc tatgagaaaa ttaagaagag
4141 gctcctatgg ggttcagatc tgggcacaat gatccgctgt gccagggctt ttggaggcct
4201 catggatgag atgaaagcaa attgtgtaaa cttaccaatc agagttggca tgaacatgaa
4261 tgaagatgga cccatcattt tcgagaaaca ttcaaagtat aagtaccatt atgatgctga
4321 ttactctagg tgggattcaa cccaacagag acatatcttg ggggctgccc ttgagataat
4381 ggttaggttc tcagctgaac ctgaattggc ccaaattgta tctgaagatc tcctagcccc
4441 cagcgtggtg gacgttggtg acttcaagat caccataaat gaaggtttac cctctggagt
4501 gccgtgcaca tcacaatgga actcaatttc ccactggcta ataacactat gtgccatatc
4561 agaaatttca gggctgtcgc cagatgtggt acaaacaaac tcctgtttct ccttctatgg
4621 ggatgatgag atagtcagca ctgacattaa gttagatccc atgaaattaa ctaacaagtt
4681 gaaggagtat ggactgatcc caacaagacc agacaagaca gaggggccac tcataatcaa
4741 agaaaacctt gatggcttga cctttctgag gagggatgtg tgtcgggacc cagctggttg
4801 gtatggaaag cttgatcaat cctcaattat gagacaattg ttttggacca aggggcccaa
4861 ccatgaagat cccaatgaga caatgattcc acactcccag aggcccatac aactaatgtc
4921 attgctgggg gaggcagcat tacacggacc agttttctac aagaaagtca gtaaattagt
4981 tatcactgag ctcaaagagg gtggaatgga tttttacgtg ccaaggcaag aacctatgtt
5041 taggtggatg agattctctg acctcagcac ttgggagggc gatcgcaatc ttgctcccga
5101 aggtgtgaat gaagatggcg tcgaatgacg ctactccatc aaatgatggt gctgccggcc
5161 tcgtgccaga aagtaacaat gaggcaatgg ctctggaacc cgtggtgggg gcgtctttag
5221 ccgcccctgt cactggccaa actaatataa tagacccctg gattagaact aattttgtcc
5281 aagcccctaa tggtgaattc acagtttccc ctagaaattc ccctggagag atattggtca
5341 atttggagtt gggtccagaa ctgaaccctt atctggcaca tttagctagg atgtacaatg
5401 gttatgcggg tggtatggag gtgcaagtga tgctcgcggg gaacgcgttc actgctggca
5461 aggtcatctt tgccgccgtg ccaccttact ttccagtgga aaatcttagc ccttctcaaa
5521 taacaatgtt cccacatgtg gttatcgatg ttagaacctt agaacctgtg ctgctcccaa
5581 tgcctgatgt cagaagcacc cttttccact ttaatcaaaa ggatgaacct aagatgagac
5641 ttgttgccat gctctacacc cctcttcgtt ctaatggctc tggtgacgat gttttcactg
5701 tttcatgtag gattcttact aggccctctc ctgaattcga tttcacatac ttggtgccac
5761 caacagtgga gtcaaagacc aagccattta cactacctgt gctgacattg ggagaattgt
5821 ccaattctag attccctctc tctattgatg aaatggtcac cagccctaat gagtccatag
5881 ttgttcagcc acagaatggt agggtcacac tagatgggga gctgttaggc acaacccaac
5941 tgcaagcatg taacatttgt tccataaggg ggaaagtgac aggacaggtc cctaatgaac
6001 aacacatgtg gaacctggag gttacaaacc taaatgggac gcaatttgac cctacagatg
6061 atgtcccagc ccctcttggt gtgcccgact ttgcaggtga ggtctttggt gtactcagtc
6121 agagaaatag aggtgaaagc aatccagcaa acagggctca tgatgctgtt gtggccacct
6181 acagtgataa atacacccct aaattgggct tagtgcaaat tgggacttgg aacaccaacg
6241 atgttgaaaa ccagccaaca aaattcaccc caattggttt gaatgaggtc gccaatggcc
6301 atcgatttga acagtggacc ttgcctaggt attctggtgc cctgacacta aatatgaact
6361 tagctcctgc tgtggccccg ctctttcctg gagagcgtct tcttttcttc cgctcttacg
6421 tcccattaaa aggtggattt ggaaaccctg ctatagattg tctagtgcct caggagtggg
6481 tccaacattt ctatcaggaa tctgccccat ctctggggga tgtggcctta gtcaggtacg
6541 tcaacccaga caccgggcgc gtcctttttg aggccaaact ccataaaggt gggttcctga
6601 ccgtgtcaag cactagcaca gggcctgttg tggttccagc caatggttat tttagatttg
6661 attcttgggt taatcaattt tactctcttg cccccatggg aactgggaat gggcgcagaa
6721 ggtttcagta atggcaggag ctttcatagc aggtttagca ggtgatgtgc ttagtaatgg
6781 cctcggttcg ctgattaatg ccggagccaa tgctatcaat caaagagcag aatttgattt
6841 caataggcaa ttgcagcaaa attcatttaa tcatgataag gagatgttaa atgcccaaat
6901 tcaagcaaca aaacagttgc aggctgatat gatagcaatc aaacagggag ttctagctgc
6961 tgggggtttc tcaccaactg atgcagccag aggagctgtc aatgcaccca tgacccaagc
7021 attagattgg agtggcacta ggtattgggc ccctggttca atgaagacca ccagctattc
7081 tggaaagttt gtgtccatga atcctgttag gcaggttgaa ttcccgcagc ccaaaaagag
7141 tgcggccata ccatcaagtg ccagctctgt gtcttctggt aggactaatt ccacaaattc
7201 tacccaatca actgttgtta gcacttcctc agtatcacct tctaggggtt cttctgctcc
7261 ttctactcta tcaagggcta caaccagaac ttccaattgg gttgaggaac aaaacaggaa
7321 tttggaaccc tatatgaggg gtgccctcca aacaacattt gtcacccctc cttccagccg
7381 ggcatctagc aacggtacag tctcaactgt accaaaaggt gttttggact cctggacacc
7441 tgcgtttaac acccgcaggc aaccgctttt cgcttacctt cgcaagaagg gggagtcaca
7501 agtttagtga aaagatgatt agtgat
//