Typing tool
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Typing tool
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Complete norovirus genomes
| MT526278 | GII.13 | |
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| GII.P16 |
ORF1: 1..5089
ORF2: 5070..6698
ORF3: 6698..7429
LOCUS MT526278 7450 bp RNA linear VRL 02-JUN-2020
DEFINITION Norovirus GII isolate 846-3 nonstructural polyprotein (ORF1) gene,
partial cds; and VP1 (ORF2) and VP2 (ORF3) genes, complete cds.
ACCESSION MT526278
VERSION MT526278.1
DBLINK BioProject: PRJNA604000
KEYWORDS .
SOURCE Norovirus GII
ORGANISM Norovirus GII
Viruses; Riboviria; Orthornavirae; Pisuviricota; Pisoniviricetes;
Picornavirales; Caliciviridae; Norovirus; Norwalk virus.
REFERENCE 1 (bases 1 to 7450)
AUTHORS Yang,Z.
TITLE Direct Submission
JOURNAL Submitted (27-MAY-2020) Molecular Virology Team/Devision of
Molecular Biology, OARSA/CFSAN/FDA, 8301 Muirkirk Rd., Laurel, MD
20708, USA
COMMENT ##Assembly-Data-START##
Assembly Method :: CLC GWB v. 11
Sequencing Technology :: Illumina
##Assembly-Data-END##
FEATURES Location/Qualifiers
source 1..7450
/organism="Norovirus GII"
/mol_type="genomic RNA"
/isolate="846-3"
/isolation_source="stool"
/host="Homo sapiens"
/db_xref="taxon:122929"
/country="USA"
/collection_date="15-Apr-2014"
/note="genotype: GII.13[P16]"
gene <1..5089
/gene="ORF1"
CDS <1..5089
/gene="ORF1"
/codon_start=2
/product="nonstructural polyprotein"
/protein_id="QKE42662.1"
/translation="ASNDATVAVACNNNNDKEKSSGEGLFTNMSSTLKKALGARPKQP
APRDNSQKPPRPPTPELVKRMPPPPPNGEEEEPVIRYEVKSGISGLPELTTVPQPDVA
NTAFSVPPLSLRENREAKEPLTGAILEMWDGEIYHYGLYVEKGLVLGVHKPPAAISMA
KVELTPLSLYWRVVYTPQYLISPETLRRLNGEAFPYTAFDNNCYAFCCWVLDLNDSWL
SRRMVQRTTGFFRPYQEWNRKPLPTMDDSKIKKVANIFLCSLSTLFTRPIKDLMGKIK
PLNILNILATCDWTFAGIVESLILLAELFGVFWTPPDVSAMIAPLLGDYELQGPEDLA
VELVPVVMGGIGLVLGFTKEKIGKMLSSAASTLRACKDLGAYGLEILKLVMKWFFPKK
EEANELAMVRAIEDAVLDLEAIENNHMTTLLKDKDSLATYMKTLDMEEEKARRLSTKS
ASPDIVGTINALLARIAAARSLVHRAKEELSSRIRPVVVMISGKPGIGKTHLAREVAR
KVASTLTGDQRVGLIPRNGVDHWDAYKGERVVLWDDYGMSNPIHDALRIQELADTCPL
TLNCDRIENKGKVFDSEVIIITTNLANPAPLDYVNFEACSRRIDFLVYAEAPEVEKAK
RDFPGQPDMWKDAFKSDFSHIKLQLAPQGGFDKNGNTPHGKGVMKTLTTGSLIARASG
LLHERMDEFELQGPTVTTFNFDRNRIAAFRQLAAENKYGLVDTMRVGNQLKGVKTMEE
LKQAIKNVTIKRCRIIYGGSTYDLESDGKGRVLVEKVKNTSVQTNNELAGALHHLKHA
RIRYYVKCVQEAVYSIIQIAGAAFVTTRIVRRMNIQELWSKPPLDQIESETKEEAPKL
EDDEFIISSKDIKEEGKKGKNKTGRGKKHTAFSSKGLSDEEYDEYKRIREERNGKYSI
EEYLQDRDRYYEELAIAKATEEDFCEEEEIKIRQRIFRPTRKQRKEERATLGLVTGSE
IRKRNPDDFKPKGKLWADDNRSVDYNEKLDFEAPPSIWSRIVSFGSGWGFWVSPSLFI
TSTHVIPAGITEAFGVPIKQIQVHKSGEFCRFRFPKPIRSDVTGMILEEGAPEGTVAT
VLIKRPTGELMPLAARMGTHATMKIQGRMVGGQMGMLLTGSNAKGMDLGTTPGDCGCP
YIYKRGNDYIVIGVHTAAARGGNTVICATQGSEGEATLEGGDDKGTYCGAPILGPGGA
PKLSTKTKFWRSSNTPLPPGTYEPAYLGGRDPRVKGGPSLQQVMRDQLKPFTEPRGKP
PRPSVLEAAKQTIINVLEQTLDPPQKWTYAQACASLDKTTSSGHPHHVRKNEFWNGET
FTGKLADQASKANLMFEEGKHMTPVYTAALKDELVKTDKVYGKIKKRLLWGSDLSTMI
RCARSFGGLMDEMKAHCISLPVRVGMNMNEDGPIIFEKHSRYKYHYDADYSRWDSTQQ
RAVLAAALEIMVRFSAEPQLAQIVAEDLLAPSVVDVGDFKISINEGLPSGVPCTSQWN
SIAHWLLTLCALSEVTKLSPDIVQANSMFSFYGDDEIVSTDIKLDPEKLTTKLKEYGL
KPTRPDKTEGPLIISEDLNGLTFLRRTVTRDPAGWFGKLDQSSILRQMYWTRGPNHED
PDETMIPHSQRPIQLMALLGEASLHGPSFYSKISKLVITELKEGGMDFYVPRQEPMFR
WMRFSDLSTWEGDRNLAPNFVNEDGVE"
mat_peptide <1..985
/gene="ORF1"
/product="p48"
mat_peptide 986..2083
/gene="ORF1"
/product="NTPase"
mat_peptide 2084..2614
/gene="ORF1"
/product="p22"
mat_peptide 2615..3013
/gene="ORF1"
/product="VPg"
mat_peptide 3014..3556
/gene="ORF1"
/product="Pro"
mat_peptide 3557..5086
/gene="ORF1"
/product="RdRp"
gene 5070..6698
/gene="ORF2"
CDS 5070..6698
/gene="ORF2"
/note="major capsid protein"
/codon_start=1
/product="VP1"
/protein_id="QKE42663.1"
/translation="MKMASNDAAPSNDGAASLVPEAINETMPLEPVAGASIAAPVAGQ
TNIIDPWIRTNFVQAPNGEFTVSPRNSPGEILLNLELGPDLNPYLAHLSRMYNGYAGG
VEVQVLLAGNAFTAGKILFAAIPPNFPVDMISPAQITMLPHLIVDVRTLEPIMIPLPD
VRNVFYHFNNQPQPRMRLVAMLYTPLRSNGSGDDVFTVSCRVLTRPTPDFEFIYLVPP
SVESKTKPFTLPILTISELTNSRFPIPIEQLYTAPNENNVVQCQNGRCTLDGELQGTT
QLLSSAVCSYRGRTVANSGDNWDQNLLQLTYPSGASYDPTDEVPAPLGTQDFSGILYG
VLTQDNVSEGTGEAKNAKGVYISTTSGRFTPKIGTIGLHSITENVHPNQQSRFTPVGV
AQNENTPFQQWVLPHYAGALALNTNLAPAVAPTFPGEQLLFFRSRVPCVQGLRGQDAF
IDCLLPQEWVNHFYQEAAPSQADVALIRYVNPDTGRTLFEAKLHRSGFITVSHTGTYP
LVVPPNGHFRFDSWVNQFYSLAPMGTGNGRRRVQ"
gene 6698..7429
/gene="ORF3"
CDS 6698..7429
/gene="ORF3"
/note="minor structural protein; small basic protein"
/codon_start=1
/product="VP2"
/protein_id="QKE42664.1"
/translation="MAGAFIAGLAGDMLTSAVGSLTSAGANAINQKLNFDYNKQLQNA
SFQHDKEMLQAQIDATKKLQSEMIAIKHGVLTAGGFSPADAARGAVNAPMTRVLDWSG
TRYYAPNSVQTTSYSGQFTPSPVHRAQVKSPSNSSQRTAAPSSIRSLSTQSTSLGSTS
SGGSSIISSSSRTADWVQQQRALSPYMQGALQTAYVTPPSSRASSMSSVSTVPKGVLD
SWTPVFNTRRQPLFAHLRKRGESQA"
ORIGIN
1 ggcgtctaac gacgctaccg ttgccgttgc ttgcaacaac aacaacgaca aggaaaaatc
61 ttcaggtgaa ggcttattca caaacatgtc ttccacctta aagaaagccc tcggggcccg
121 gcccaaacag cctgccccga gggacaactc acaaaagccc ccgagaccac caactcccga
181 gttggttaag aggatgcccc ctcccccacc taacggagaa gaagaagaac cagtcattag
241 gtatgaggtt aagagtggaa tctctggcct gcccgagctc acaacagtcc ctcaaccgga
301 tgtggccaac acggcattca gtgtcccacc gctgagcttg agagaaaaca gggaggccaa
361 ggaaccgctg acaggggcaa tattagagat gtgggatgga gagatatacc actatggcct
421 gtacgtggag aaaggcttag tgttgggtgt gcacaaacca cctgcagcta taagcatggc
481 aaaagtggag ctgacgccgt tgtcattgta ctggcgtgtg gtctacaccc cccaatacct
541 catctcccct gaaactctca ggaggctcaa cggagaggca ttcccttaca ctgcctttga
601 caacaactgc tatgcctttt gctgttgggt attagacctc aatgactcat ggcttagcag
661 gaggatggtg caaagaacaa caggcttctt cagaccttac caagagtgga acagaaaacc
721 cctgcccact atggatgact ccaaaatcaa gaaggtggca aacatattcc tgtgctcatt
781 gtccacgttg ttcaccagac ctataaaaga cctcatggga aaaattaagc cattaaacat
841 cttgaacatc ctggcaacgt gtgactggac attcgccgga atagtggagt ctcttatatt
901 acttgctgaa ctctttggag ttttctggac acccccagat gtgtctgcta tgatcgctcc
961 tttacttgga gactacgagt tgcaagggcc agaagacctt gccgttgagc tcgtacctgt
1021 agtaatggga gggattggtt tggtgttggg attcaccaaa gagaaaattg gaaaaatgtt
1081 gtcctcagca gcatcaacgc tcagggcttg taaagatctt ggtgcctatg gcttagagat
1141 actcaaactg gtcatgaagt ggttcttccc aaagaaagaa gaggccaatg agctagccat
1201 ggtgagagct atagaggatg ctgtactgga tcttgaggca atagaaaata atcacatgac
1261 aactctgttg aaggacaaag acagcctagc gacctacatg aaaacactag acatggagga
1321 ggaaaaggcc agaagattgt ccacaaaatc tgcatcccct gacatagttg ggacgatcaa
1381 cgccctgctg gctcgaatag cagcggctag gtcactagtc cacagggcca aggaggagtt
1441 gtctagcagg ataagaccag tggttgttat gatatctggc aagccaggga taggcaaaac
1501 tcatttggcc agggaagtgg caagaaaggt ggcatccact ctcacagggg atcaaagagt
1561 cgggctcata ccgagaaacg gtgtggacca ttgggatgca tacaaaggtg agagagtcgt
1621 gctgtgggac gactatggca tgagcaaccc cattcatgat gctctgcgca tacaagaatt
1681 ggctgacacg tgtcccctta ccttaaattg tgacagaatt gaaaataagg gaaaagtttt
1741 tgacagtgaa gtcataataa tcacaacaaa ccttgccaat ccagctccac ttgattatgt
1801 caactttgag gcctgttcca ggagaattga cttcctggtg tacgccgagg caccagaagt
1861 agaaaaggca aaacgagact ttcctggtca accagatatg tggaaggacg ccttcaagtc
1921 ggacttttca catatcaagc tgcaacttgc acctcagggc ggctttgaca agaatggcaa
1981 caccccacat gggaaaggag tgatgaagac cctcaccacc ggttccctga tcgcccgtgc
2041 atcaggctta ctgcatgaga ggatggatga atttgaactc caaggcccca cagtcaccac
2101 ctttaatttt gaccggaaca gaatcgctgc attcagacaa ttggctgcag aaaacaagta
2161 tggattggtg gacaccatga gagttggcaa tcaattaaaa ggggtgaaaa ccatggaaga
2221 gctcaaacaa gcaatcaaga atgtgaccat caagaggtgc cggatcatct acggcggctc
2281 cacgtatgac cttgaatctg acggtaaggg cagagttctg gtggaaaagg tcaagaacac
2341 ctctgtacag accaacaacg agttggccgg agccctgcat cacctcaaac atgcccgaat
2401 caggtactat gtcaaatgtg tgcaagaagc agtctactct attatacaaa tcgccggcgc
2461 tgcgtttgtc accacacgca tagtacgccg catgaacata caagagcttt ggtcgaagcc
2521 accattagat caaattgaat cagagactaa ggaagaggcc cccaagttag aagatgacga
2581 gttcatcata tcttctaagg acatcaagga ggaaggaaag aagggcaaaa acaaaactgg
2641 ccgtggcaag aaacatactg cattctctag caagggcttg agcgatgagg agtacgacga
2701 gtacaagagg ataagagaag agagaaatgg gaagtactct atagaggagt atcttcaaga
2761 cagagacagg tactatgagg aactcgccat cgccaaggcc acggaagaag acttctgtga
2821 ggaggaggag atcaaaatcc gtcagaggat cttccgtccc accaggaagc aaaggaagga
2881 agagagggcc acactagggc tagtaactgg ttcagaaatc agaaaaagaa accctgatga
2941 cttcaaacct aaagggaaac tgtgggctga tgacaacaga agtgttgact acaatgagaa
3001 actggacttt gaggcccccc caagcatatg gtctaggatt gtgagttttg gttctggttg
3061 gggcttctgg gtgtcaccaa gcctgttcat aacatcaact cacgtaatcc ctgcaggcat
3121 aacagaggca tttggagtcc ccatcaaaca aatccaggtc cacaaatcag gtgaattttg
3181 ccggttcaga ttcccaaaac caattagatc agatgtgaca ggaatgatct tggaagaagg
3241 tgcgcctgag ggcaccgtgg caaccgtgct catcaaacgc cctaccggag agctcatgcc
3301 ccttgcagcc agaatgggaa cacacgcaac catgaaaatt cagggccgca tggttggcgg
3361 acagatgggt atgttgctca ctggttcaaa tgctaaagga atggatttgg gaacaactcc
3421 tggtgattgt ggctgtccct acatctacaa aaggggcaat gactatatag tcattggggt
3481 gcacacagca gcagcccgtg gtggaaacac cgtcatctgt gccacacagg gaagtgaggg
3541 tgaggcaacc cttgagggtg gagatgacaa aggaacatac tgtggggcac ccattctagg
3601 ccccgggggg gcaccaaaat tgagcaccaa aaccaaattt tggaggtcat cgaacacgcc
3661 tcttccacca gggacgtatg agcctgccta cctcggtggc cgtgacccgc gtgttaaggg
3721 tgggccctcc ttgcagcagg taatgagaga ccagttgaag ccattcaccg agcccagggg
3781 taaacctcca agaccaagtg tgttggaagc agccaaacaa accatcatca atgtcctcga
3841 acaaaccctg gaccctccac aaaaatggac atacgcacag gcgtgtgctt cacttgacaa
3901 aaccacctcc agcgggcacc cccaccacgt ccgaaagaat gaattctgga atggtgagac
3961 cttcactggt aaattggcag accaagcatc aaaagcaaat ctaatgtttg aggaagggaa
4021 acacatgaca ccagtgtata cagcagccct caaggatgag ctggtcaaga ctgacaaagt
4081 ctatggaaag atcaagaaga gactgctctg gggctctgac ttgtccacca tgatccggtg
4141 cgccaggtcc tttggtgggc tcatggatga gatgaaagca cactgcatat cactcccagt
4201 ccgagttggc atgaacatga atgaagatgg tccaataata tttgagaagc actccagata
4261 caagtatcac tatgatgcag attactcccg ctgggattca acacaacaga gggcagtact
4321 agcagcagcc ttggagatca tggtcaggtt ctctgcagag ccacaattgg cacaaatagt
4381 cgctgaggat ctgctggccc ccagtgtggt agatgtagga gactttaaaa tttcaataaa
4441 tgaagggctc ccctctggtg taccatgcac ttctcaatgg aattccatcg cacactggct
4501 gctaaccctc tgcgccttgt ctgaagtcac caaactgtct cctgacattg tacaggcaaa
4561 ctccatgttc tcattttacg gtgatgacga gattgtcagc accgatataa aattggaccc
4621 tgaaaagtta accaccaaat tgaaggagta tggcctgaaa ccaactcgcc cagacaaaac
4681 cgagggaccc ctgatcatca gtgaggattt gaacggactc actttcctcc ggagaacggt
4741 gactcgtgac ccagctggct ggtttggaaa attggaccaa agctcaatat tgaggcagat
4801 gtactggact agaggaccaa atcatgaaga ccccgacgag acaatgatac cccactctca
4861 aagacccata cagcttatgg cactgcttgg tgaggcctcc cttcacggac cctccttcta
4921 cagcaaaatt agtaagttgg tcataactga actcaaagaa ggtgggatgg atttttacgt
4981 gccaaggcag gaacccatgt tcaggtggat gaggttttct gacttgagca cgtgggaggg
5041 cgatcgcaat ctggctccca attttgtgaa tgaagatggc gtcgaatgac gccgctccat
5101 cgaatgatgg tgcagctagt ctcgtaccag aggccattaa tgagactatg ccattggaac
5161 ccgttgctgg cgcatctatt gctgccccag tggcgggaca aactaacata attgacccct
5221 ggataagaac aaattttgtg caagccccta atggagagtt cacagtatca ccgagaaatt
5281 cccctggaga gattctatta aatttagagt taggaccaga tttgaatcct tatttggccc
5341 atctgtcaag gatgtacaat ggatatgctg gaggtgttga ggtgcaagtg cttcttgctg
5401 ggaacgcgtt cacagcagga aagatattat ttgcagcaat cccacccaac tttcctgtag
5461 atatgattag cccagctcaa attactatgc ttccccattt gattgtagat gttaggacat
5521 tggaacctat tatgataccc ttaccagatg ttaggaatgt gttctatcat tttaataatc
5581 aaccccaacc taggatgaga ttagtggcta tgctctatac cccattgaga tctaatggtt
5641 caggagatga tgtctttact gtgtcttgta gagtgttgac taggccaacc cctgactttg
5701 aatttattta cctagtgcct ccctctgtag agtccaaaac taaaccattc acacttccaa
5761 tattgaccat ttctgaacta accaactccc ggtttcccat cccaattgag caactgtata
5821 cggccccaaa tgagaataat gttgtacagt gtcaaaatgg aaggtgcacc ttggatggag
5881 agcttcaggg caccacccag ctgctatcaa gtgcagtttg ctcttacagg ggtaggactg
5941 tggctaacag tggggacaat tgggaccaga atctgctcca gctgacctac ccaagcggtg
6001 caagctatga ccccactgat gaagtaccag cacccttggg cacccaggat ttcagtggga
6061 tattgtatgg ggtgttaacc caagacaatg tgagtgaggg tacaggggag gccaaaaatg
6121 ctaagggagt atacatatcc accaccagtg gaagattcac cccaaaaatt gggacaattg
6181 gattgcattc aataactgaa aatgtgcacc ccaatcagca atcacggttc acccccgttg
6241 gagtcgctca gaatgaaaac acccccttcc agcaatgggt tctaccacac tacgcaggtg
6301 ctctcgctct aaacaccaat ttggcacccg ctgttgcccc gactttccct ggcgagcaat
6361 tactgttctt caggtcccgt gttccatgtg ttcaaggtct gcgggggcag gatgctttca
6421 tagattgtct cctacctcaa gagtgggtga accattttta tcaagaggct gctccctccc
6481 aagcagacgt tgctctcatc aggtatgtca accctgatac tggtcgcacg ctgtttgagg
6541 ccaaattgca caggtcaggt ttcattactg tgtcacacac tggtacctac ccccttgtgg
6601 tccccccaaa tggtcatttc aggtttgatt cttgggttaa ccaattctac tcactcgccc
6661 ccatgggaac tggcaatggg cgcagaagag ttcaataatg gcaggagcat ttatagctgg
6721 tctagccggt gacatgctga cttctgctgt tggttcactg acctctgcag gagccaatgc
6781 catcaatcag aaattgaatt ttgattacaa taaacaactc caaaatgcat cctttcaaca
6841 tgataaggaa atgttgcagg cccaaattga tgctacaaag aagctccaat cagaaatgat
6901 tgcaattaag catggggttt tgaccgcggg cggcttttcc ccagctgatg cagccagagg
6961 ggcagtcaac gccccaatga ctcgagtgtt ggattggtca gggacacgct actacgctcc
7021 aaattctgtg caaaccacca gttattctgg gcaattcacc ccctcgccag tccatcgggc
7081 gcaggtgaag tccccttcca attcatctca gcggactgca gctccaagca gtatccgcag
7141 cctgtcaacc caatcaactt ctttaggctc cacctcctca ggggggtcct ctataatctc
7201 ctctagttcg aggacagcag actgggtgca acaacaaagg gctcttagcc cgtacatgca
7261 gggagccctg cagacggcat acgtcacacc gccgtctagt agggcttcca gtatgagctc
7321 tgtctcaaca gtgcccaaag gggttttgga ctcctggaca cctgtgttta acacacgcag
7381 gcagccgctg tttgcacacc tcaggaagag gggggagtca caggcttagt gaaaaggata
7441 atcaactctt
//