Typing tool
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Typing tool
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Complete norovirus genomes
| MT357991 | GI.1 | |
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| GI.P1 |
ORF1: 5..5374
ORF2: 5358..6950
ORF3: 6950..7588
LOCUS MT357991 7654 bp RNA linear VRL 25-APR-2020
DEFINITION Norovirus GI isolate Hu/US/2018/GI.1[P1]/CS0091, complete genome.
ACCESSION MT357991
VERSION MT357991.1
KEYWORDS .
SOURCE Norovirus GI
ORGANISM Norovirus GI
Viruses; Riboviria; Orthornavirae; Pisuviricota; Pisoniviricetes;
Picornavirales; Caliciviridae; Norovirus; Norwalk virus.
REFERENCE 1 (bases 1 to 7654)
AUTHORS Randazzo,W., Houston,K., Montmayeur,A.M., Tatusov,R.L., Chhabra,P.,
Browne,H., Barclay,L. and Vinje,J.
TITLE Direct Submission
JOURNAL Submitted (17-APR-2020) Division of Viral Diseases, Centers for
Disease Control and Prevention, 1600 Clifton Road NE, Atlanta, GA
30329, USA
COMMENT ##Assembly-Data-START##
Assembly Method :: Geneious v. 11.1.2; SPAdes v. 3.6
Sequencing Technology :: Illumina
##Assembly-Data-END##
FEATURES Location/Qualifiers
source 1..7654
/organism="Norovirus GI"
/mol_type="genomic RNA"
/strain="CS0091"
/isolate="Hu/US/2018/GI.1[P1]/CS0091"
/isolation_source="stool"
/host="Homo sapiens"
/db_xref="taxon:122928"
/country="USA"
/collection_date="26-Jun-2018"
/note="genotype: GI.1[P1]"
gene 5..5374
/gene="ORF1"
CDS 5..5374
/gene="ORF1"
/codon_start=1
/product="nonstructural polyprotein"
/protein_id="QJC14582.1"
/translation="MMMASNDAVPTAASSENANNNSSIKSRLLARLKGVSGTTAPPNS
IQITNQNMALGLIGQAPAPKATAVEAPKQQRDRPPRTAAEVQQNLCWTEKPQDQNVKA
WDELDHTTKQQILDEHAEWFDAGGLGPSTLPSNHERHPNDDSGGHQVKWSAKEGVNLG
IDGLTTVPGPEWNMCPLPPADQRSTTPAVEPIIGDMIEFYEGHIYHYAIYIGQGKTVG
VHSPQAAFSITRITIQPISAWWRVCYVPQPKQRLTYDQLKELENEPWPYAAVTNNCFE
FCCQVMCLEDTWLQRKLISSGRFHHPTQDWSRDTPEFQQDSKLEMVRDAVLAAINGLV
SRPFKDLLGKLKPLNVLNLLSNCDWTFMGVVEMAILLLELFGVFWNPPDVSNFIASLL
PDFHLQGPEDLARDLVPVVLGGIGLAIGFTRDKVSKMMKNAVDGLRAATQLGQYGLEI
FSLLKKYFFGGDQTEKTLKDIESAVIDMEVLSSTSVTQLVRDKQSARAYMAILDNEEE
KARKLSVRNADPHVVSSTNALISRISMARAALAKAQAEMTSRMRPVVIMMCGPPGIGK
TKAAEHLAKRLANEIRPGGKVGLVPREAVDHWDGYHGEEVMLWDDYGMTKIQEDCNKL
QAIADSAPLTLNCDRIENKGMQFVSDAIVITTNAPGPAPVDFVNLGPVCRRVDFLVYC
TAPEVEHTRKVSPGDTNALKDCFKPDFSHMKMELAPQGGFDNQGNTPFGKGVMKPTTI
NRLLIQAVALTMERQDEFQLQGPTYDFDTDRVSAFTKMARANGIGLVSMASLGKKLRG
VSTIEGLKNALLGYKIAKCSIQWQSRVYIIESDGSNVHIKEDKQALTPLQQTINTASL
AITRLKAARAVAYASCFQSAVTTILQMAGSALVINRAVKRMFGTRTAAMALEGPEKEH
NCRVHKAKEAGKGPIGHDDMIEKFGLCETEEEESEDQIQMTPNDAIPEGKNKGKTKKG
RGRKNNYNAFSRRGLSDEEYEEYKKIREEKNGNYSIQEYLEDRQRYEEELAEVQAGGD
GGIGETEMEIRHRVFYKSKSRKHQQEQRRQLGLVTGSDIRKRKPIDWTPPKNEWAEDD
REVDYNEKINFEAPPTMWSRVTKFGSGWGFWVSPTVFITTTHVVPTGVKEFFGEPLTN
IAIHQAGEFTQFRFSKKIRPDLTGMVLEEGCPEGTVCSVLIKRDSGELLPLAVRMGAI
ASMRIQGRLVHGQSGMLLTGANAKGMDLGTIPGDCGAPYVHKRGNDWVVCGVHAAATK
SGNTVVCAVQASEGETALEGGDKGHYAGHEIVRHGNGPALSTKTKFWRSSPEPLPPGV
YEPAYLGGKDPRVQNGPSLQQVLRDQLKPFAEPRGRMPEPGLLEAAVETVTSMLEQTM
DTPSPWSYADACQSLDKTTSSGFPHHKRKNDDWNGTTFVRELGDQAAHANNMYENGKH
MKPIYTAALKDELVKPEKVYQKIKKRLLWGADLGTVIRAARAFGPFCDAIKSHVIKLP
IKVGMNTIEDGPLIYAEHAKYKNHFDADYTAWDSTQNRQIMTESFSIMSRLTASPELA
EVVAQDLLAPSEMDVGDYVIRVKEGLPSGFPCTSQVNSINHWIITLCALSEATGLSPD
VVQAMSYFSFYGDDEIVSTDIDFDPARLTQILKEYGLRPTRPDKTEGPIQVRRNVDGL
VFLRRTISRDAAGFQGRLDRASIERQIFWTRGPNHSDPSETLVPHTQRKVQLISLLGE
ASLHGEKFYRKISSKVIHEIKTGGLEMYVPGWQAMFRWMRFHDLGLWTGDRNLLPEFV
NDDGV"
mat_peptide 5..1198
/gene="ORF1"
/product="p48"
mat_peptide 1199..2287
/gene="ORF1"
/product="NTPase"
mat_peptide 2288..2890
/gene="ORF1"
/product="p22"
mat_peptide 2891..3304
/gene="ORF1"
/product="VPg"
mat_peptide 3305..3847
/gene="ORF1"
/product="Pro"
mat_peptide 3848..5371
/gene="ORF1"
/product="RdRp"
gene 5358..6950
/gene="ORF2"
CDS 5358..6950
/gene="ORF2"
/note="major capsid protein"
/codon_start=1
/product="VP1"
/protein_id="QJC14583.1"
/translation="MMMASKDATSNVDGASGAGQLVPEANTSDPLAMDPVAGSSTAVA
TAGQVNPIDPWIINNFVQAPQGEFTISPNNTPGDVLFDLSLGPHLNPFLLHLSQMYNG
WVGNMRVRIMLAGNAFTAGKIIVSCIPPGFGSHNLTIAQSTLFPHVIADVRTLDPIEV
PLEDVRNVLFHNNDRNQQTMRLVCMLYTPLRTGGGTGDSFVVAGRVMTCPSPDFNFLF
LVPPTVEQKTRPFTLPNLPLSSLSNSRAPLPIGSMGISPDNVQSVQFQNGRCTLDGRL
VGTTPVSLSQVGKVRGTSNGTVINLTELDGTPFHPFEGPAPIGFPDLGGCDWHINMTQ
FGHSSQTQFDVDTTPETFVPHLGSIQANGVGSGNYIGVLSWISPPSHPSGSQVDLWKI
PNYGSSVTEATHLAPSVFPPGFGEVLVFFMSKIPGPGAYNLPCLLPQEYISHFASEQA
PTVGEAALLHYVDPDTGRNLGEFKAYPDGFLTCVPNGSSSGPQQLPINGVFVFVSWVS
RFYQLKPVGTASTARGRLGLRR"
gene 6950..7588
/gene="ORF3"
CDS 6950..7588
/gene="ORF3"
/note="minor structural protein; small basic protein"
/codon_start=1
/product="VP2"
/protein_id="QJC14584.1"
/translation="MAQAIIGAIAASTVGSALGAGIQVGGEAALQSQRYQQNLQLQEN
SFKHDKEMIGYQVEASNQLLAKNLATRYSLLRAGGLSSADAARSIAGAPVTRIVDWNG
VRVSAPESSATTLRSGGFMSVPIPYASKQKQIQPSGISNPNYSPSSISRTASWVESQN
SLRFGNLSPYHTEALNTVWLTPPGSTASSTLSSVPRGYFNTDRLPLFANNRR"
ORIGIN
1 gtgaatgatg atggcgtcta acgacgctgt tcctactgct gctagcagtg aaaatgctaa
61 caacaacagt agtatcaagt ctcgcctatt ggcgagactt aaaggtgtga gcggaacaac
121 agctccacct aattctatac aaataactaa ccaaaatatg gctttggggc taattggcca
181 ggccccagca ccaaaggcca cggccgtgga ggcccccaaa caacagaggg ataggcctcc
241 gcggactgct gccgaagtcc aacaaaactt atgttggacc gagaaaccgc aggaccaaaa
301 tgtcaaggcg tgggacgaac tagaccacac aacaaaacaa cagatacttg atgagcatgc
361 tgaatggttt gatgctggtg gtttgggccc aagcacactc cctagcaacc atgaacgtca
421 cccaaacgat gatagtggag gccaccaagt taaatggtcg gctaaagagg gtgtgaatct
481 cggaatagat gggctcacaa ctgttcccgg gcctgagtgg aacatgtgcc cgctaccccc
541 agcagaccaa aggagcacga cgcctgcagt cgagcctata ataggtgata tgatcgaatt
601 ttatgaaggt cacatctacc attatgccat ctatatcggt caaggcaaga cagtgggtgt
661 ccattctcct caagcagcat tctcaataac aagaatcacc atacaaccta tatcagcatg
721 gtggcgggtg tgctacgtcc cacagccaaa acagagactt acatatgatc aactcaaaga
781 attggagaac gaaccatggc catacgccgc ggtcaccaat aactgctttg aattctgttg
841 ccaagttatg tgcctagaag acacttggct acaaagaaag ctcatctcct ctggacgatt
901 ccaccatcca acccaggatt ggtctcggga cactccagaa ttccaacaag acagcaaact
961 tgagatggtc agagatgcag tgctagccgc gataaatggg ttagtatcgc ggccctttaa
1021 ggatctctta ggcaaactta aacctttgaa tgtgctcaac ttgctttcaa attgtgattg
1081 gacatttatg ggggtcgtgg aaatggcgat cctccttttg gagctttttg gagtgttctg
1141 gaatccaccc gatgtgtcca attttatagc ttcactccta ccagattttc atctacaggg
1201 ccctgaagac cttgctagag accttgtgcc agtggtcttg ggcggtattg gtctagccat
1261 aggatttact agggacaagg tgagtaagat gatgaagaat gctgtcgacg gactgcgggc
1321 tgcaacccag ctcgggcagt atggcctgga aatattctca ctattaaaga agtacttctt
1381 tggtggagac cagacagaga agaccctaaa agacatagaa tcagctgtca ttgacatgga
1441 ggtgttgtca tccacctcag tgacccagct cgtgagggat aaacaatctg cgcgggctta
1501 catggctatc ttggataatg aagaagaaaa agctaggaaa ctgtccgtca ggaatgctga
1561 tccacacgtg gtatcttcca ccaatgctct catatcccga atatcaatgg ctagagccgc
1621 cctagccaag gcccaggctg aaatgactag caggatgcgt cctgtagtca ttatgatgtg
1681 tggaccccct ggcataggaa agaccaaggc agcggaacac ctggccaaac ggttggccaa
1741 cgaaatacgg cctggtggta aagttggact agtcccacgt gaagctgtgg accattggga
1801 tggttatcat ggtgaggaag tgatgttatg ggatgactat gggatgacca aaatacagga
1861 ggattgcaac aaactacaag ccatagctga ctcggccccc ctgacgctca attgcgatcg
1921 aatagagaat aaagggatgc aattcgtgtc tgatgctata gtcataacca ctaatgcccc
1981 tggcccagcc cccgtggact ttgtcaatct cggacctgtt tgtcgaaggg tggacttcct
2041 tgtgtactgt acggctccag aagtggaaca cacgaggaaa gttagccctg gcgacactaa
2101 tgcactaaag gactgtttta aacctgactt ttctcacatg aaaatggaac tcgcccccca
2161 gggtggtttt gataaccaag ggaacacccc gtttggcaaa ggtgtaatga aaccaaccac
2221 cataaacagg ttattgatcc aagctgtggc attgacaatg gagaggcagg atgagttcca
2281 acttcaaggt cccacttatg actttgatac tgatagggtc tctgcattta caaagatggc
2341 ccgagctaat gggataggtc ttgtgtccat ggcctcctta ggcaagaaat tgcgtggggt
2401 ttccaccatt gaaggtttga agaatgccct tctagggtac aagatagcaa agtgcagcat
2461 acagtggcag tcaagggtgt acatcataga atcagatggt agtaatgtac acatcaagga
2521 ggacaagcaa gccctaaccc ccctacaaca aacaattaac acagcctcct tggctatcac
2581 acgacttaaa gcagctaggg ctgtggctta cgcctcatgc ttccaatctg ctgtcaccac
2641 catattacaa atggcagggt ctgcattggt catcaatcgg gcagtcaagc gcatgtttgg
2701 cacccgtacg gcagccatgg cgctagaggg accagaaaaa gaacacaatt gcagggttca
2761 taaagctaag gaggctggga agggacctat aggacacgat gacatgatag aaaagttcgg
2821 tctgtgtgag actgaagagg aagaaagtga agaccaaatc caaatgaccc caaatgatgc
2881 cattccagaa gggaagaaca aaggtaagac caagaaaggc cgcggccgca aaaacaatta
2941 caatgcattc tcccgacgtg ggctgagtga tgaggagtat gaagaataca agaagatcag
3001 ggaagagaag aatggtaatt acagcataca agaatatttg gaggatcgtc aacggtatga
3061 ggaagagttg gcagaggtcc aagcaggtgg cgacggcggt ataggggaga ctgagatgga
3121 gattcgccac agagttttct acaaatccaa aagcagaaag caccaacagg aacagcgacg
3181 tcaactcggc ctggtaactg gatcggacat caggaaacgc aagcctattg attggacccc
3241 accaaagaat gaatgggctg aagatgacag ggaagttgac tataatgaaa agatcaattt
3301 tgaggccccc ccaacaatgt ggagccgggt tacaaagttt gggtcaggat ggggcttctg
3361 ggtcagtcca accgtgttca ttaccaccac gcatgtggtg ccaactggcg tgaaggaatt
3421 ctttggcgaa cctctcacca atatagcaat ccatcaagca ggtgagttca cacagttcag
3481 gttctccaag aagatacgcc ctgacctgac gggcatggtg ttggaggaag gctgccctga
3541 aggaacagtt tgttcagtcc tgatcaaacg agactcaggc gagcttctcc cactggctgt
3601 ccgtatgggg gccattgcct ctatgaggat acagggccgc cttgttcatg gccaatcagg
3661 aatgctactg acaggagcga atgcaaaagg gatggacctt gggactatac caggggattg
3721 tggagcgcca tacgtccaca agcgcggtaa cgactgggtc gtgtgcggag tccacgctgc
3781 agccacaaaa tcaggcaaca ctgtggtctg tgctgtgcag gctagtgaag gtgagaccgc
3841 gttagaaggc ggagacaaag ggcactatgc gggtcatgaa attgtgaggc acgggaatgg
3901 cccggcattg tcaactaaaa caaaattctg gagatcctcc ccagagccat tgccccctgg
3961 tgtttatgag cctgcatacc taggaggaaa ggacccacgt gtccagaatg gtccctccct
4021 tcaacaggtt ctgcgtgacc aattgaaacc cttcgcagaa ccccgtggcc gcatgcctga
4081 acctggtttg ctggaggcgg cggtcgagac tgtaacatcc atgttagaac aaacaatgga
4141 cactccaagc ccatggtctt atgctgatgc ctgtcaatct cttgataaaa ctacaagctc
4201 aggctttccc caccacaaaa ggaagaacga tgattggaac ggtactacct ttgtcaggga
4261 gcttggtgat caggctgcac atgctaacaa catgtatgag aatggcaaac acatgaaacc
4321 catctataca gcagctttga aagatgagtt agtcaaaccc gaaaaggtct accaaaagat
4381 caaaaagcgc ctattatggg gtgccgacct cgggactgta atcagagctg cccgagcttt
4441 tggcccattc tgtgatgcta taaagtcaca tgtcatcaag ctaccaataa aggttggcat
4501 gaacacaata gaagatggcc ccctgattta tgctgagcat gccaagtaca aaaaccactt
4561 tgatgcggat tacacagcat gggactcaac gcagaataga caaatcatga cagaatcctt
4621 ctccatcatg tcacgcctta cggcctctcc tgagctggcc gaagtcgtgg cccaagattt
4681 attggcacca tctgagatgg atgtgggtga ctatgtcata agagttaagg aaggcttacc
4741 atctgggttc ccgtgtactt cccaagtgaa tagcataaat cattggataa ttaccctctg
4801 tgcactctct gaagccactg gtctgtcacc tgacgtagtg caagccatgt catacttctc
4861 attttatggc gatgatgaaa ttgtgtcaac tgacatagat tttgacccag cccgtctcac
4921 ccaaatcctt aaggaatatg gtctcaggcc aacaaggcca gataaaactg aagggccaat
4981 acaggtcagg aggaatgtgg atggattagt tttcttgcgc cgcaccatct cccgtgacgc
5041 tgcagggttc cagggtaggc tagacagggc ctcaattgaa cggcaaattt tctggacccg
5101 cgggcccaac cattcagacc cctcagagac gttagtgccg catacccaaa gaaaagtgca
5161 attgatctca ctcttaggag aggcttcact ccatggagaa aagttctata gaaagatctc
5221 cagcaaagtc atacatgaaa ttaagactgg tgggttggag atgtatgtcc cagggtggca
5281 ggccatgttc cgctggatgc gcttccatga cctcggattg tggacaggag atcgcaatct
5341 tctgcccgaa ttcgtaaatg atgatggcgt ctaaggacgc tacgtcaaac gtggatggcg
5401 ccagtggcgc tggtcagttg gtaccggagg ctaacacttc tgaccccctt gcaatggatc
5461 ctgtggcagg ttcttcgacg gcggttgcga ctgctggaca agtaaacccc attgaccctt
5521 ggataattaa taattttgtg caagctcccc aaggggagtt cacaatctct ccaaataata
5581 cccccggtga tgttttattt gatctgagtt taggtcccca tcttaatccc ttcttgctac
5641 atctgtcaca aatgtataat ggttgggttg gtaatatgag agttaggatt atgttggccg
5701 gcaatgcctt tactgcaggt aagatcatag tttcctgtat acctcctggt tttgggtcgc
5761 ataatcttac tatagcacaa tcaactctat tcccacatgt gattgctgat gttaggactt
5821 tagaccctat tgaagtacct ctggaagatg ttaggaatgt tctctttcat aataatgata
5881 ggaaccaaca aactatgcgc cttgtgtgca tgttatatac ccctctccgc actggtggtg
5941 gtacaggtga ttcctttgtt gtggcggggc gagtcatgac ctgccctagt cctgatttta
6001 atttcttgtt tttggttccc cccacagtgg agcagaaaac taggcctttc acccttccaa
6061 atttgccttt gagctctttg tccaactcac gtgctcctct tccaattggc agcatgggca
6121 tttctccaga caatgttcag agtgtacaat tccaaaatgg tcggtgtact ttggacggtc
6181 gtttggttgg caccacccca gtttcactgt cccaggttgg caaggtaagg ggcacttcca
6241 atggcactgt catcaacctc actgaattgg atggtacacc ttttcaccct tttgaaggcc
6301 ctgcccccat tggattccca gatctcggtg gttgtgactg gcacatcaac atgacacaat
6361 ttggccactc tagtcagaca caatttgatg tggataccac ccctgaaacc tttgtccctc
6421 atttaggttc aatccaggca aatggtgttg gtagtggcaa ttacattggt gttctcagtt
6481 ggatctcccc cccatcacac ccttctggtt cccaggtaga cctttggaag atccccaatt
6541 atgggtcgag cgttactgag gcaacacacc tggccccatc agtgttccca cccggctttg
6601 gggaagtgct ggttttcttc atgtcgaaga taccaggacc tggcgcctac aatctgccat
6661 gcctgctgcc acaagagtac atctcacact ttgcaagtga gcaagccccc actgtgggtg
6721 aggccgctct gctccattat gttgaccctg atacagggcg gaaccttggg gagttcaaag
6781 cataccccga tggatttctc acttgtgtcc ccaatggatc cagctcaggt ccacaacaat
6841 taccaatcaa tggagttttt gtttttgtct cttgggtatc taggttctat caattgaagc
6901 ctgtgggaac tgccagtacg gcaagaggta ggcttggact gcgccgataa tggcccaagc
6961 tataattggt gcaattgctg cctccacagt aggcagtgcc cttggggcag gtatacaggt
7021 tggtggtgag gcagcactcc aaagtcaaag atatcaacag aatctgcaat tgcaagagaa
7081 ttcctttaaa catgacaaag aaatgattgg atatcaagtt gaggcttcaa atcaactgct
7141 agccaagaat cttgcaacca gatactcact ccttcgtgct ggaggtctat ccagtgctga
7201 cgcagcaagg tccatcgcgg gagccccagt gacccgaatc gtggattgga atggtgtgag
7261 agtgtcagct cctgaatctt ctgcaactac attgaggtct ggtggcttta tgtcagtgcc
7321 aataccatat gcatctaagc aaaaacagat tcaaccatct ggtattagta atccaaatta
7381 ctctccttct tccatttctc gaaccgctag ttgggttgaa tcacaaaatt cattaagatt
7441 tgggaatcta tccccatacc atacagaggc ccttaacaca gtgtggttga ccccacctgg
7501 ttcaacagca tcctccacac tgtcttctgt gccacgtggt tatttcaata cagatagatt
7561 gccattgttc gcaaacaata ggcgataatg ttgtaatatg aaatgtgggc atcatattca
7621 gttaattagg tttaattaga tttgatttga tgtt
//