Typing tool
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Typing tool
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Complete norovirus genomes
| MT238669 | GII.17 | |
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| GII.P17 |
ORF1: 1..5091
ORF2: 5072..6694
ORF3: 6694..7473
LOCUS MT238669 7489 bp RNA linear VRL 01-MAY-2020
DEFINITION Norovirus GII isolate 691-2 nonstructural polyprotein (ORF1) gene,
partial cds; and VP1 (ORF2) and VP2 (ORF3) genes, complete cds.
ACCESSION MT238669
VERSION MT238669.1
DBLINK BioProject: PRJNA604000
KEYWORDS .
SOURCE Norovirus GII
ORGANISM Norovirus GII
Viruses; Riboviria; Orthornavirae; Pisuviricota; Pisoniviricetes;
Picornavirales; Caliciviridae; Norovirus; Norovirus norwalkense.
REFERENCE 1 (bases 1 to 7489)
AUTHORS Yang,Z., Williams-Hill,D., Wolfe,J., Silva,A.J., Hirneisen,K.,
Ruelle,S., Kulka,M. and Hellberg,R.
TITLE Direct Submission
JOURNAL Submitted (24-MAR-2020) Molecular Virology Team/Devision of
Molecular Biology, OARSA/CFSAN/FDA, 8301 Muirkirk Rd., Laurel, MD
20708, USA
COMMENT ##Assembly-Data-START##
Assembly Method :: CLC Genomics Workbench v. 11
Sequencing Technology :: Illumina
##Assembly-Data-END##
FEATURES Location/Qualifiers
source 1..7489
/organism="Norovirus GII"
/mol_type="genomic RNA"
/isolate="691-2"
/isolation_source="stool"
/host="Homo sapiens"
/db_xref="taxon:122929"
/geo_loc_name="USA"
/collection_date="17-Nov-2015"
/note="genotype: GII.P17-GII.17"
gene <1..5091
/gene="ORF1"
CDS <1..5091
/gene="ORF1"
/codon_start=1
/product="nonstructural polyprotein"
/protein_id="QIQ09394.1"
/translation="DASAAVAGKNNNNDKEKSSSDSLFANMSVTFKKALGARSKQPPP
GETKQIQKPPRPPTPELVKRIPPPPPNGEDEPGIVYKVGEGVSGLPDLTTVVQPDAQN
TAYSVPPLSQREVGEAKEPLPGSILEMWDGEIYHYGLYVERGHVLGVHKPPAAISFAK
IEITPLSLYWRVVYTPQYLIDPGTLKNLSGETFPYTAFDNNCYAFCCWVLDLNDSWLS
RRMIQRTTGFFKPYQDWNRKPLPTMDEPKIKKAANAVLCALSSLFTRPIKDIIGKLRP
LNILNILATCDWTFAGIVESLILLAELFGVFWTPPDVSAMIAPLLGDYEMQGPEDLAV
ELVPVVMGGIGLVLGFTKEKIGKMLSSAATTLRACKDLGSYGLEILKLVMKWFFPKKE
EANELAMVRAIEDAVLDLEAIENNHMTTLLKDKDSLATYMRTLDLEEEKARKLSTKSA
SPDIVGTINALLARIAAARSLVHKAKEELSSRQRPVVVMISGRPGIGKTHLARELAKK
VASTLSGDQRIGLVPRNGVDHWDAYKGERVVLWDDYGMSNPIQDALRLQELADTCPLT
LNCDRIENKGKVFDSDAIIITTNLANPAPLDYVNFEACSRRIDFLVYADAPDIEKAKR
DFPGQPDMWKDHFRPDFSHIKLQLAPQGGFDKNGNTPHGKGVVKSLTIGSLIARASGL
LHERMDEFELQGSDLPTFNFDRNKVAAFRQLAAENKYGLMDTLRVGNQLKNVKTLDEL
KQAIKNISIKKCQIVYNGCTYTMESDGRGKVVVEKVQNATVQTNNELVGALHHLRSAR
IRYYVKCFQEAIYSLLQIAGAAFVTSRIVRRMNISNLWSKPPIEEGDEPEDRGGCPKP
RDEDDLTIDSRDIKVEGKKGKNKSGRGKKHTAFSSKGLSDEEYDEYKRIREERNGKYS
IEEYLQDRDRYYEELAIAKATEEDFCEEEEIKIRQRIFRPTRKQRKEERATLGLVTGS
EIRKRNPDDFKPKGKLWADDNRSVDYNERIDFEAPPSVWSRIVNFGTGWGFWVSPSLF
ITSTHVIPKGITDAFGVPINQIQIHKSGEFCRLRFPKPIRPDVSGMILEEGAPEGTVV
SILIKRTTGELMPLAVRMGTHATMKIQGRTVGGQMGMLLTGSNAKSMDLGTTPGDCGC
PYIYKRGNDLVVIGVHTAAARGGNTVICATQGSEGEATLEGGDNKGTYCGAPILGPGN
APKLSTKTKFWRSSNAPLPPGTYEPAYLGGRDPRVKGGPSLQQVMRDQLKPFTEPRGK
PPNPNVLESAKKTIINVLEQTIDPPQKWSYAQACASLDKTTSSGYPHHVRKNDYWSGE
SFTGKLADQASKANLMYEEGKHMQPVYTAALKDELVKTDKIYGKIKKRLLWGSDLSTM
IRCARAFGGLMDEFKANCITLPIRVGMNMNEDGPIIFEKHSRYRYHYDADYSRWDSTQ
QRAVLEAALEIMVRFSAEPQLAQIVAEDLLSPSVVDVGDFKIAINEGLPSGVPCTSQW
NSIAHWLLTLCALSEVTGLGPDIIQANSMYSFYGDDEIVSTDIKLDPEKLTAKLKEYG
LKPTRPDKTEGPLVISEDLNGLTFLRRTVTRDPAGWFGKLDQNSILRQLYWTRGPNHE
DPSETMIPHAQRPVQLMALLGESSLHGPSFYSKVSKLVISELKEGGMDFYVPRQESMF
RWMRFSDLSTWEGDRNLAPSFVNEDGVE"
mat_peptide <1..981
/gene="ORF1"
/product="p48"
mat_peptide 982..2079
/gene="ORF1"
/product="NTPase"
mat_peptide 2080..2616
/gene="ORF1"
/product="p22"
mat_peptide 2617..3015
/gene="ORF1"
/product="VPg"
mat_peptide 3016..3558
/gene="ORF1"
/product="Pro"
mat_peptide 3559..5088
/gene="ORF1"
/product="RdRp"
gene 5072..6694
/gene="ORF2"
CDS 5072..6694
/gene="ORF2"
/note="major capsid protein"
/codon_start=1
/product="VP1"
/protein_id="QIQ09395.1"
/translation="MKMASNDAAPSNDGAAGLVPEGNNETLPLEPVAGAAIAAPVTGQ
NNIIDPWIRTNFVQAPNGEFTVSPRNSPGEILLNLELGPDLNPYLAHLSRMYNGYAGG
VEVQVLLAGNAFTAGKILFAAVPPNFPVEFLSPAQITMLPHLIVDVRTLEPIMIPLPD
VRNTFFHYSNQLNSRMRLVAMLYTPLRSNGSGDDVFTVSCRVLTRPTPDFEFTYLVPP
SVESKTKPFSLPILTLSELTNSRFPVPIDSLFTAQNNVLQVQCQNGRCTLDGELQGTT
QLLPTAICAFRGRVTAQINQRDRWHMQLQNLNGTTYDPTDDVPAPLGTPDFKGVVFGM
VSQRNVGNDAPGSTRAQQAWVSTYSPQFVPKLGSVNLRISDNDDFQFQPTKFTPVGVN
DDDDGHPFRQWELPNYSGELTLNMNLAPPVAPNFPGEQLLFFRSFVPCSGGYNQGIID
CLIPQEWIQHFYQESAPSQSDVALIRYVNPDTGRTLFEAKLHRSGYITVAHSGDYPLV
VPANGHFRFDSWVNQFYSLAPMGTGNGRRRAQ"
gene 6694..7473
/gene="ORF3"
CDS 6694..7473
/gene="ORF3"
/note="minor structural protein; small basic protein"
/codon_start=1
/product="VP2"
/protein_id="QIQ09396.1"
/translation="MAGAFIAGLAGDMLTSSVGSLVNAGANAINQKIDFENNKQLQSA
SFQHDKEMLQAQVRATKQLQSEMIALKQGVLAAGGFSPTDAARGSIGAPMTKVLDWSG
TRYWAPNSTKTTGYSGQFTSAPVHMSSPNAPQSKPVKPRSLAPSSSSSSVYSMYTQST
HLTSGSSSNASSASTKLTNLSSGSSQNRTAEWVNQQRSLSPFMSGALNISHVTPPSSR
ASSSGTVSTVPKEVLDSWTSAFNTHRQPLFAHLRVRGESRV"
ORIGIN
1 gacgcttccg ctgccgttgc tggcaaaaac aacaacaacg acaaggaaaa atcttcaagt
61 gacagcttgt ttgctaacat gtctgtcact tttaagaaag ccctcggggc gcggtctaaa
121 caaccgcccc cgggagaaac aaaacaaata caaaaaccac caaggccacc gacaccggaa
181 ttggtgaaga gaatacctcc acccccaccc aatggcgagg atgaaccagg gatagtgtac
241 aaggtgggag agggtgtgtc tgggctgccc gacctaacaa ctgtggtaca acctgacgca
301 caaaacacag cttatagtgt tcccccactt agccagagag aagtcggcga agctaaagaa
361 ccgctgcctg gctccattct ggaaatgtgg gatggtgaga tctatcacta tgggctgtat
421 gttgagcggg ggcatgtgct cggagtacac aaaccacctg ctgcaataag ctttgccaaa
481 attgaaataa caccgctgtc tctctactgg agagtggtct acactcccca gtatttgata
541 gatccaggaa ctcttaagaa cttgagtgga gagactttcc catacacggc ctttgacaac
601 aactgttatg ccttctgttg ttgggtccta gacctcaacg actcctggct tagcaggaga
661 atgatccaaa gaacaactgg attcttcaaa ccttatcagg attggaacag aaaaccctta
721 ccaaccatgg atgaaccgaa aatcaagaag gccgcgaatg ctgtcctatg cgctctctcc
781 tcactcttca ctagacccat taaggacatc attggaaagc ttagaccact gaacattctt
841 aatatactgg caacctgcga ttggactttt gcaggcatag tggaatcctt gatccttctt
901 gctgaactct ttggggtgtt ctggacaccc ccagatgtgt ctgcgatgat tgctccctta
961 ctcggtgact acgagatgca aggccccgaa gacctggccg tggaacttgt gcccgtggtg
1021 atgggaggaa taggtttggt gttaggattc accaaagaaa agatcggcaa gatgctttca
1081 tcagctgcga ccacacttag ggcctgcaag gatctaggat cttatggatt ggagatactc
1141 aaattggtca tgaagtggtt cttccccaag aaggaggagg ctaacgaact agccatggtg
1201 agggccattg aggatgcagt cctggatttg gaggcaatag aaaacaatca catgaccacc
1261 cttctcaagg ataaagacag cctggccaca tacatgagga ctcttgactt ggaagaagag
1321 aaagcaagga aactgtcaac caaatcggcg tcacctgaca tcgtgggtac aataaacgca
1381 ttgttggcta ggatagcagc cgccaggtca ctggtccaca aggctaagga ggagctctca
1441 agcagacaga ggcctgttgt tgtaatgata tcaggtagac caggtatagg aaagacccat
1501 ctggccagag agctagccaa gaaagttgcg tcaacactgt caggcgacca aaggattgga
1561 ctggtaccta gaaatggcgt cgaccattgg gacgcctaca agggagaaag ggtggtcctg
1621 tgggatgatt atggtatgag caaccctata caggacgcac tgaggctcca agaattggct
1681 gacacctgtc ctctgaccct aaattgtgat aggattgaaa acaaaggaaa agtgttcgac
1741 agtgatgcca taattataac aaccaacctt gcaaacccag caccactaga ctatgtcaac
1801 tttgaggcct gctctagacg catagacttc ttggtgtatg cagacgcacc tgacattgag
1861 aaggctaagc gtgacttccc tggccaacca gatatgtgga aagaccattt cagaccagac
1921 ttctcacaca ttaaacttca gctggcacca cagggaggtt ttgacaaaaa tggcaacacc
1981 ccacatggca aaggtgtggt gaagtccctg acgattggtt ctctgatcgc cagggcctcc
2041 ggcttgctcc acgagagaat ggatgaattc gagctccaag gctctgacct gccaaccttc
2101 aattttgacc gcaacaaagt cgccgccttc agacaattag cagctgaaaa caaatatggt
2161 cttatggaca cattgagggt cggcaaccaa ctgaaaaatg ttaagaccct ggatgagctg
2221 aagcaggcca taaagaacat cagtatcaag aagtgtcaga tagtgtataa tggatgcacc
2281 tataccatgg aatctgatgg gaggggcaag gttgtggttg aaaaggtaca aaacgcaaca
2341 gttcaaacca acaatgaact tgtaggggcg ctccaccacc tgagatctgc aaggataaga
2401 tactatgtta aatgtttcca agaagccatt tactctctac tccaaattgc tggtgcagcc
2461 ttcgtcacct cacgcatcgt gaggcgcatg aacatatcaa acctctggtc gaagccaccc
2521 atcgaggagg gtgatgagcc tgaagacaga ggaggatgcc ccaagcccag ggatgaagat
2581 gacctcacta ttgactctag agacattaaa gtggaaggga agaagggcaa gaacaagtct
2641 ggccggggca agaaacacac agccttctct tccaagggcc tcagtgatga agagtacgat
2701 gagtacaaga gaatcagaga ggagaggaat ggcaaatact caatagagga atacctccaa
2761 gatagggaca gatactatga agagcttgcc attgctaagg ccactgagga ggacttctgt
2821 gaggaggagg agatcaaaat ccgccagaga atcttccgac ccaccaggaa gcagcggaaa
2881 gaggaaaggg ccacgcttgg gcttgtcaca ggatcggaaa tcagaaagag gaatccagat
2941 gactttaaac caaaaggaaa attgtgggct gacgacaaca ggagcgtgga ttacaatgag
3001 aggatagatt ttgaggctcc cccgagtgtt tggtctagga tagtcaactt tggcacaggc
3061 tggggattct gggtttctcc aagtcttttt ataacttcaa cacacgtcat accaaaagga
3121 atcactgatg cctttggagt gcccataaac caaatccaaa ttcacaaatc tggagaattt
3181 tgccgcttgc ggtttccaaa gccaattaga ccagacgtga gtgggatgat cttggaagag
3241 ggcgcccctg aaggcactgt tgtgtctatt cttatcaaga ggacaacagg ggagctgatg
3301 cctcttgcag tcagaatggg gactcatgcc acaatgaaaa tccaaggtag aacggtgggt
3361 ggtcagatgg gtatgcttct cactggctca aatgctaaaa gcatggatct aggcacaacg
3421 ccaggtgact gcggatgtcc atacatatac aaaaggggca atgaccttgt ggtcattggg
3481 gtacacactg cagcagctcg tggaggcaac acggtcatat gtgccacaca gggaagtgaa
3541 ggtgaagcca ctcttgaagg aggtgacaac aagggtacct attgtggagc ccccattttg
3601 ggacctggca atgcaccaaa attgagcaca aagacaaaat tctggagatc ctctaacgca
3661 ccgcttcccc caggtactta tgaaccagca taccttggtg ggagagaccc gcgcgtgaag
3721 ggaggcccat ctctgcaaca agttatgaga gaccaactta aaccttttac agagcccaga
3781 gggaagccac caaacccaaa tgtcttagag tcagcaaaga agactatcat caatgttctg
3841 gaacaaacca ttgacccccc tcaaaagtgg tcatatgccc aagcttgtgc atccctcgac
3901 aagacaacct ccagtggata cccgcaccac gtccggaaga atgactattg gagtggtgaa
3961 tcctttacag gaaaacttgc ggatcaggct tcaaaagcaa atctcatgta tgaggaaggc
4021 aagcacatgc aaccagttta caccgcagca ctcaaagacg agctcgtgaa aactgacaaa
4081 atttatggca aaatcaagaa aagactcctg tggggttctg acctctccac aatgattcga
4141 tgcgccagag catttggtgg tctcatggat gaattcaaag caaattgtat tacgctccct
4201 atcagagttg gtatgaatat gaatgaagat ggtcccataa tatttgagaa acactccagg
4261 tacaggtacc actatgatgc tgattactcc cgctgggact ccacacaaca gcgggcagtg
4321 ctggaagcgg cacttgaaat catggtgaga ttttctgctg agccacagct ggcacaaata
4381 gtggcagagg acctgctgtc accaagtgtg gttgatgtgg gcgatttcaa aatcgctatc
4441 aatgaaggcc taccatctgg cgtgccttgc acctcacaat ggaattctat tgcccactgg
4501 ttacttacct tgtgtgccct ttctgaagtg acaggattag gtcctgacat catacaagct
4561 aactccatgt actctttcta tggtgatgat gagattgtga gcacagacat aaaattggac
4621 ccagagaaat tgaccgcaaa gctcaaagaa tatggcctta aacccactcg gcccgacaaa
4681 actgaggggc cgttggtgat tagtgaggac ctgaatgggt tgactttcct ccgccgaaca
4741 gtcacccgtg atccagcagg ttggtttgga aagttggacc aaaactccat cctcaggcag
4801 ttgtactgga caagaggacc caaccatgaa gaccccagtg agaccatgat accacacgca
4861 caaagacctg tgcagctcat ggcactacta ggagaatcct ccctacatgg accctcattt
4921 tacagcaagg ttagcaaatt agtcatatct gaacttaaag agggaggaat ggatttttat
4981 gtgcccagac aagagtcaat gttcagatgg atgaggttct cagatctaag cacatgggag
5041 ggcgatcgca atctggctcc cagttttgtg aatgaagatg gcgtcgaatg acgccgctcc
5101 atctaatgat ggtgctgctg gtctcgtacc agagggcaac aacgagaccc ttcccctaga
5161 accagttgcg ggcgcagcta tagccgcacc cgtcactggc caaaataata taattgaccc
5221 ctggattaga acaaattttg tgcaagcacc aaatggagag ttcacagtgt cacccagaaa
5281 ctctcctgga gaaattttat taaatttaga gttgggccct gatttgaacc cttatttggc
5341 tcatttgtca aggatgtaca acgggtatgc tggtggagtg gaagttcagg ttctcctggc
5401 agggaacgcg ttcactgccg gaaagatcct cttcgccgcc gtcccgccaa atttcccagt
5461 ggaattctta agcccagccc agatcacaat gctcccacat ttaatagtag atgttaggac
5521 tcttgaacca attatgatcc cactccctga tgttaggaat acattcttcc attatagtaa
5581 ccagcttaac agccgcatga gattagtggc tatgctctat accccactca gatctaatgg
5641 ctcaggtgat gatgtcttta ctgtctcttg tagggttttg actaggccta ctcctgattt
5701 tgagttcact tatttagtgc caccttctgt tgaatccaaa actaagcctt tttccttacc
5761 tattttaacc ctttctgagc tcacaaattc gaggtttcca gtccccatcg attcgctttt
5821 caccgcccag aataatgtgt tgcaggtgca gtgtcaaaat ggcaggtgta cacttgatgg
5881 tgagttacaa ggcacaaccc agttgctccc aactgccatc tgtgcattca gaggacgggt
5941 gacagcacaa attaaccaac gtgacaggtg gcacatgcaa ctgcaaaacc tcaatggtac
6001 aacatatgac ccaactgatg atgtgccagc cccgctgggt acacctgact tcaagggcgt
6061 cgtgtttggg atggtaagcc aaagaaatgt gggtaatgat gcgcctggct caaccagagc
6121 ccaacaggcg tgggtttcaa cctatagccc ccaatttgtc cccaaattag gttctgtcaa
6181 tcttagaatt agtgataatg atgatttcca attccagccg acaaaattca caccagtggg
6241 cgtcaatgat gacgatgatg gccacccgtt cagacaatgg gaactaccaa actattcagg
6301 ggagcttacc ttgaatatga atcttgcccc cccagttgct ccaaattttc ctggtgaaca
6361 attgttattc ttcagatctt tcgtgccatg ctcaggaggt tacaaccaag gtattataga
6421 ttgtcttatt ccccaagaat ggatccaaca cttctatcag gaatcagcac cctcccagtc
6481 agacgtggcc ctaatcaggt atgtcaaccc cgatacggga cgtacactgt ttgaagcaaa
6541 attgcacaga tctggttaca ttactgtggc tcactctgga gactatcctc ttgttgttcc
6601 ggctaatgga cactttagat ttgattcttg ggtaaatcag ttttactcac tcgccccaat
6661 gggaactggg aatgggcgaa ggagggctca gtaatggctg gggctttcat tgcaggattg
6721 gcaggcgaca tgctcacgtc atctgtgggc tcccttgtga acgcaggggc aaacgccatc
6781 aaccaaaaga tagactttga aaacaacaaa caactccagt ctgcttcctt tcagcatgat
6841 aaagagatgc tccaagcgca ggtgagggca accaagcagc tgcaatctga aatgatagcc
6901 ctaaagcagg gggttttggc cgcaggcggc ttttccccca ctgatgcagc aaggggatcc
6961 attggtgcac ccatgacaaa ggtgcttgac tggtctggca ctcgatactg ggcgcccaat
7021 tccacaaaga caactggcta ttcgggacaa ttcacctctg cacctgtgca tatgtctagc
7081 ccaaatgctc cacaatcaaa acctgtaaag cctaggtctc tagctccttc ctcttcttct
7141 agcagtgtct atagtatgta tactcaatct acacatttaa catctggctc ttctagtaat
7201 gcttcttctg cctccacaaa attgacaaat ttaagctctg gctcctctca aaacagaaca
7261 gcagagtggg taaatcaaca gagaagtctt agccctttca tgagtggcgc acttaacatc
7321 tcacatgtca cgccaccctc aagtagggct tccagttctg ggacggtctc gaccgtgccc
7381 aaggaagttt tggactcctg gacgtctgcg tttaatacac acagacagcc gctcttcgca
7441 cacctcagag tgagggggga gtcacgtgtt tagtgaaaag aaataattg
//