Typing tool
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Typing tool
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Complete norovirus genomes
| MT089580 | GI.3 | |
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| GI.P3 |
ORF1: 1..5394
ORF2: 5378..7015
ORF3: 7015..7662
LOCUS MT089580 7735 bp RNA linear VRL 01-MAY-2020
DEFINITION Norovirus GI isolate 461-3 nonstructural polyprotein (ORF1) gene,
partial cds; and VP1 (ORF2) and VP2 (ORF3) genes, complete cds.
ACCESSION MT089580
VERSION MT089580.1
DBLINK BioProject: PRJNA604000
KEYWORDS .
SOURCE Norovirus GI
ORGANISM Norovirus GI
Viruses; Riboviria; Orthornavirae; Pisuviricota; Pisoniviricetes;
Picornavirales; Caliciviridae; Norovirus; Norwalk virus.
REFERENCE 1 (bases 1 to 7735)
AUTHORS Yang,Z., Williams-Hill,D., Wolfe,J., Silva,A.J., Hirneisen,K.,
Ruelle,S., Kulka,M. and Hellberg,R.S.
TITLE Direct Submission
JOURNAL Submitted (13-FEB-2020) Molecular Virology Team/Devision of
Molecular Biology, OARSA/CFSAN/FDA, 8301 Muirkirk Rd., Laurel, MD
20708, USA
COMMENT ##Assembly-Data-START##
Assembly Method :: CLC Genonics Workbench v. 11
Sequencing Technology :: Illumina
##Assembly-Data-END##
FEATURES Location/Qualifiers
source 1..7735
/organism="Norovirus GI"
/mol_type="genomic RNA"
/isolate="461-3"
/isolation_source="stool"
/host="Homo sapiens"
/db_xref="taxon:122928"
/country="USA"
/collection_date="24-Jul-2019"
/note="genotype: GI.P3-GI.3"
gene <1..5394
/gene="ORF1"
CDS <1..5394
/gene="ORF1"
/codon_start=1
/product="nonstructural polyprotein"
/protein_id="QIC52028.1"
/translation="MASNDAIAVADVSNNNANTNNDNIGSRLMARIRGRIGPQRGETT
TKIKDANMALDLLRRSQTPSPSRQESPPKSQRDRPPRTASEVKKVLGWDVEPEHQEST
AKAWCDLTQEEKEEIMRNNEKLFDAGGITPSTLPSTFERADPVDSPTEQQPVTWSASG
GVDIGVNDLTTVRGPFWNMCPLPPLDARSNGPAKEPLIGDMIEFYEGHIFHYAIYIGQ
GKTIGVHSPQAAFSIPRITIHPLVAWWRVCYVPNNQQRLTYDQLKELENEPWPYASIT
NNCYEFCCRVMALDDTWLERRLVSTGKFNHPTQDWSQDTPDFHQDSKLEMVRDAVLSA
INGLVSQPFRNILSKIKPLNVLNLLSNCDWTFMGVVELIVLLAELFDVFWTPPDISSF
IASLLPEFHLQGPEDLARDLVPLILGGIGLAIGFTRDKITKVMKSAVDGLRSATQLGQ
YGLEIFSIIKKYFFGGDQTEKTLRGIEDAVIDMEVLSSTNVTQLVKDKKLARTYMNVL
DNEEEKARKLSVRSADPHIVTSVNNLISRISMARSALAKAQAEMTSRPRPVVIMMCGP
PGIGKTKAAEHLAGRLANEIRPGGKVGLVPRESIDHWDGYHGEDVLLWDDYGMSKITE
DCNKLQAIADTAPLSLNCDRIENKGMQFSSDAIIITTNAPGPAPVDFVNLGPVCRRVD
FLVYCSAPEIEQMRRTHPGDANAIKDLYKRDYSHLKMELAPQGGFDSQGNTPFGKGTM
KPTTLNRLLIQATALAMERQDEFQLQGAVYNFDEDRVSAFTSLARANGLGLLSMATLG
KRLRSVKSMEGLRNALVGYKIGECDIIWNTRVYSIKSDGSTVTIKEKQTPTSPQYQAI
STATLALSRLRAARALAYASCLQSAVLSILQVAGSALVVSRAVKRMFGTRTEQPMLEG
KHKEHNCRVHRAEAAGHGPIGHDGVIERYGLCESEQEEEGEQIFELPTANKEGKNKGK
TKKGRGRKSNFNAFSRRGLSDEEYEEYKKIREEKSGNYSIQEYLEDRQRYEEELAEVQ
AGGDGGIGETEAEIRHRVFYKSKSGMRKQRQEERRQLGLVSGSEIRKRKPIDWTPPKN
DWSEDTRTVNYDEHISFEAPPSIWSRVVKFGSGWGFWVSSTVFITTTHVIPPGAKEVF
GEDLSNVAIHRVGEFTQFRFSKKMRPDLTGMVLEEGCPEGTVCTIMIKRDSGELLPLA
VRMGAVASMKIQGKLMHGQSGMLLTGANAKGMDLGTIPGDCGAPYVHKRGNDWVVCGV
HAAATKSGNTVVCAIQGGDGEATLEGGGQNKGHYAGHPILRYGNGPSLSTKTKFWKST
PQPLPPGTYEPAYLGGRDPRVEGGPSLQQVLRDQLKPFAEPRGRLPEAGLLEAAVETV
TNAIEQVMDTPVAWSYSDACMSLDKTTSSGHPHHKKKNDDWNGNSFVRELGDQAALAN
SMYELGKSMKPVYTAALKDELVKPDKVYTKIKKRLLWGADLGTVIRAARAFGPFCEAI
KPHVIKLPIKVGMNAIEDGPLIYAEHSKYKFHYDADYTAWDSTQNREIMMESFNIMCK
LTANPSLAAVVAQDLLSPSEMDVGDYVISVKDGLPSGFPCTSQVNSINHWILTLCALS
EVTGLSPDVIQSQSYFSFYGDDEIVSTDIEFDPIRLTQILKEYGLKPTRPDKTDGPII
IRQQVDGLVFLRRTISKDAIGYQGRLDRNSIERQLWWTRGPNHEDPFETLVPHSQRKV
QLISLLGEAALHGEKFYRKIAGRVIQEVKEGGLEIYIPGWQAMFRWMRFHDLSLWTGD
RDLLPDYVNDDGV"
mat_peptide 1..1215
/gene="ORF1"
/product="p48"
mat_peptide 1216..2304
/gene="ORF1"
/product="NTPase"
mat_peptide 2305..2904
/gene="ORF1"
/product="p22"
mat_peptide 2905..3324
/gene="ORF1"
/product="VPg"
mat_peptide 3325..3867
/gene="ORF1"
/product="Pro"
mat_peptide 3868..5391
/gene="ORF1"
/product="RdRp"
gene 5378..7015
/gene="ORF2"
CDS 5378..7015
/gene="ORF2"
/note="major capsid protein"
/codon_start=1
/product="VP1"
/protein_id="QIC52029.1"
/translation="MMMASKDAPTNMDGTSGAGQLVPEANTAEPISMEPVAGAATAAA
TAGQVNMIDPWIMNNYVQAPQGEFTISPNNTPGDILFDLQLGPHLNPFLSHLAQMYNG
WVGNMKVKVLLAGNAFTAGKIIISCIPPGFAAQNISIAQATMFPHVIADVRVLEPIEV
PLEDVRNVLFHNNDNTPTMRLVCMLYTPLRASGSSSGTDPFVIAGRVLTCPSPDFSFL
FLVPPNVEQKTKPFSVPNLPLNTLSNSRVPSLIKSMMVSRDHGQMVQFQNGRVTLDGQ
LQGTTPTSASQLCKIRGNVFHANGGNGYNLTELDGSPYHAFESPAPIGFPDLGECDWH
MEASPTTQFDTGDVIKQINVKQESAFAPHLGTIQADGLNDVSVNTNMIAKLGWVSPVS
DGHKGDVDPWVIPRYGSTLTEAAQLAPPIYPPGFGEAIVFFMSDFPIAHGINGLSVPC
TIPQEFVTHFVNEQAPIRGEAALLHYLDPDTHRNLGEFKLYPDGFMTCVPNSSGTGPQ
TLPINGVFVFVSWVSRFYQLKPVGTAGPARRLGIRRS"
gene 7015..7662
/gene="ORF3"
CDS 7015..7662
/gene="ORF3"
/note="minor structural protein; small basic protein"
/codon_start=1
/product="VP2"
/protein_id="QIC52030.1"
/translation="MAQAILGAIAATAAGSAVGAGIQAGTEAALQHQRFQQDLTLQKN
SFIHDKEMMGLQVEASTALLQNSLGTRYNMLTKAGMTSADAARMVVGAPATRVVDWNG
TRIAAPMSTATTLRSGGFMTVPTVYRGSKNKQSVGGGFSNVNYDPSVSSSRTSQWVSS
QNSMRSTLEPFHPGALRTTWVTPPGSTSTSTISTVSTVPKFFNTERLPLFANRGK"
ORIGIN
1 atggcgtcta acgacgctat tgccgttgct gatgtcagca ataacaatgc taacaccaac
61 aatgataata ttggatcccg cctcatggcg aggatccgtg ggcgcatagg cccacaacgt
121 ggtgaaacaa ccacaaagat aaaagacgcc aatatggcgc ttgatctgct acgccggtca
181 caaacaccct ccccatcccg gcaagagagc cctcctaaga gccaaaggga ccgcccccct
241 cggactgctt ctgaggtgaa gaaagtattg gggtgggatg ttgaaccaga acaccaggaa
301 agcacggcca aggcatggtg tgacctcacg caggaagaga aggaggagat aatgcgcaat
361 aatgaaaagc tcttcgatgc tgggggaatc actccatcaa ctttgcccag cacgtttgaa
421 agggccgacc cagttgatag tcccactgaa cagcaacctg taacatggtc tgctagtggc
481 ggggttgata ttggtgtcaa tgacttgacc actgtccgcg gcccattttg gaatatgtgc
541 cccctcccac cattggatgc tcggagtaat ggccccgcca aggagcccct cataggagac
601 atgatagagt tctatgaggg tcatatattc cattatgcca tctatattgg gcaaggtaag
661 accattggag ttcactcacc gcaagcagct ttctccatac caaggataac catccatccc
721 ctggtagcct ggtggcgtgt gtgctacgtt ccaaataacc agcagcgcct cacttatgac
781 caactgaaag aattggagaa tgagccatgg ccctatgctt ccattacaaa caattgttac
841 gagttctgct gcagggtgat ggcacttgac gacacatggc ttgagaggag attggtcagc
901 actggaaaat tcaaccaccc cacacaagac tggtcacagg ataccccgga ttttcaccaa
961 gattcgaaac ttgagatggt gagagatgca gtgctatcag ctattaatgg ccttgtgtca
1021 caacccttta gaaacatctt gtcaaagatc aaaccattaa atgttcttaa tctcttgtca
1081 aactgtgatt ggaccttcat gggggttgtg gaactaatcg tgctcctagc agagctgttt
1141 gatgtgttct ggaccccacc agacatttca agtttcattg cctcactact acctgaattt
1201 cacctgcagg gtccagaaga cctagctagg gacttggtcc ccctcatcct aggaggcata
1261 ggtttggcta ttggctttac aagagacaaa atcacgaaag tgatgaagag tgccgtcgat
1321 gggctgagat cggcgacaca gcttgggcag tacggactgg aaatattctc aatcatcaag
1381 aagtatttct ttggtgggga ccaaacggaa aagaccttgc ggggtattga ggatgcagtg
1441 atagacatgg aggtattatc tagcaccaat gtgacacaac tggttaaaga caagaaattg
1501 gccagaacct acatgaatgt gctagataat gaagaggaaa aagcaaggaa actctcagtc
1561 cgtagtgctg atccacacat agtgacctca gtcaacaatc tgatatcacg gatatctatg
1621 gcaagatcag ccttggccaa agcccaggct gagatgacat ctcgcccacg ccctgtggtc
1681 ataatgatgt gtggcccccc cggcattgga aaaaccaagg ccgctgaaca tctggctggc
1741 cgattggcga acgagattag accaggaggt aaggttggac ttgtgcctcg ggagtctata
1801 gatcattggg acggatatca tggagaggat gtcctactat gggacgacta tggcatgtca
1861 aagataacag aggactgtaa caagctacaa gccatagctg acactgcacc cctatcactt
1921 aattgtgaca ggatagagaa caaaggtatg caattctcct cagatgcaat aattataacc
1981 accaatgccc ccggcccagc accggtggac tttgtcaacc taggccctgt gtgcaggcga
2041 gtggactttt tagtttactg ttctgccccc gaaattgaac aaatgagaag gacccaccct
2101 ggtgatgcca atgccatcaa agacctatac aaaagggact attcacactt aaaaatggag
2161 ttggccccac aaggtggttt tgatagtcag ggtaacacac catttgggaa gggcaccatg
2221 aaacccacga ccctcaacag gctactcatt caggcaacag cattagctat ggagcggcaa
2281 gatgagttcc agctccaagg ggctgtctac aattttgatg aagatagggt gtccgccttc
2341 acaagcctgg ctcgagccaa cggcctgggg ctcttaagca tggcgacatt gggaaagagg
2401 ctcagaagtg tcaagtctat ggagggcctg cgcaatgcat tggtgggtta caaaatagga
2461 gagtgtgata taatctggaa cactagagtg tattcaatta aaagtgatgg tagtactgtc
2521 acaatcaagg aaaaacaaac cccaacttca cctcaatatc aggccattag cacagccact
2581 cttgcactct ctagattgcg ggccgctaga gctctcgcgt acgcctcctg cctgcagagt
2641 gcagtgctgt caatacttca agtagctggc tctgccctgg tggtgagcag agccgttaag
2701 cgcatgtttg gcactcgcac tgaacaacct atgttggaag gcaagcacaa agaacataac
2761 tgcagagtgc accgcgcaga ggcagctggc catggtccta ttggacacga tggagtcatc
2821 gaacgctatg gcctttgtga gagtgagcaa gaagaagaag gcgagcaaat ttttgagtta
2881 cccactgcca ataaagaagg taaaaacaag ggcaagacca aaaagggccg tggacgaaaa
2941 tccaatttta acgctttctc aagacgaggc ctcagtgatg aagagtatga agaatacaag
3001 aagatcagag aagaaaagag tggtaattac agcatccagg agtaccttga ggaccgccaa
3061 cgatatgagg aagaacttgc tgaagtgcag gctggtggag atggtggaat tggtgagact
3121 gaagcagaga ttcgccatcg ggtcttctat aaatcaaaat ctggtatgag aaagcaacgc
3181 caagaagaac ggcgtcagtt gggcctcgtt agcggttctg agattcgcaa acgcaagccc
3241 atagactgga ccccccctaa gaatgactgg tcagaagaca ccaggactgt caattatgat
3301 gaacacatta gctttgaagc ccctccctca atttggagta gggtggtaaa gtttggcagt
3361 ggttggggtt tttgggtgag ctcaacagtg ttcataacca caacccatgt tataccacct
3421 ggggctaaag aagtctttgg tgaagacctc agtaatgtgg ccatccatag agttggtgag
3481 tttacccagt tccgtttctc caaaaagatg agacctgacc tcactggtat ggtcttagaa
3541 gaaggttgcc cagagggaac agtgtgtacc ataatgatta agagagattc tggtgagttg
3601 ctgccgctcg ccgttcgaat gggggcagtg gcatcaatga agatccaagg caaacttatg
3661 catgggcaat caggaatgtt actcaccggt gctaatgcca agggcatgga ccttggaact
3721 atacccggtg attgtggggc accctatgtc cacaagaggg gaaacgactg ggtggtctgt
3781 ggagtacatg cagccgccac aaaatcaggc aacactgtgg tgtgcgccat acagggtggc
3841 gatggtgaag ccactctgga gggtggcggt caaaacaagg gccactatgc agggcatccg
3901 atactaaggt atgggaatgg cccttcgcta tcaaccaaaa caaaattttg gaagtcaacc
3961 ccccagcctt tgccccctgg tacatatgag ccagcttacc ttggaggcag agatcccaga
4021 gttgaggggg gcccatcctt acaacaggtg ttaagggacc agttaaagcc atttgccgag
4081 ccccgtggca gattgcccga agcaggcttg ttggaagctg cagttgagac ggtcaccaat
4141 gccattgaac aggtcatgga cacaccggtg gcatggagct acagcgatgc ttgcatgtcc
4201 ctggataaga caaccagttc cggccatccc catcacaaga agaaaaatga tgactggaat
4261 gggaattcat ttgtgagaga attgggcgac caggcggcgc ttgctaacag catgtacgag
4321 cttggtaagt ccatgaaacc agtgtataca gcagccctaa aggatgagct ggtcaaacca
4381 gacaaggtgt acacaaaaat caaaaagaga ctgctttggg gcgcggacct tggtaccgtc
4441 atccgcgctg ccagagcatt tggaccattt tgtgaagcca taaaacccca tgtaattaag
4501 ctgcctatca aggtgggtat gaatgccata gaggacggcc ctttgattta tgcagagcac
4561 tccaaatata aatttcatta tgatgctgac tacacagctt gggattcaac acaaaataga
4621 gaaatcatga tggaatcttt caacattatg tgtaagctca cagccaatcc ctcccttgcc
4681 gcagtggtgg cgcaggatct actctcccca tctgaaatgg atgttggtga ttatgtgatc
4741 agtgtcaaag atggtttgcc atcaggcttt ccgtgcacct cacaggtgaa cagtatcaac
4801 cattggattc taaccctgtg cgctctgtca gaagtcactg gcttgtcccc agatgtgata
4861 cagtcacaat cctacttctc attttatggt gatgatgaaa tagtctcaac agacatagaa
4921 tttgacccaa ttaggttgac acaaatactg aaggaatatg gtctgaagcc tacaagacct
4981 gacaaaactg atggcccaat tattatcaga cagcaggttg atggtctggt ctttctccgg
5041 cgcaccattt ctaaggatgc cattggatac cagggacgac tcgaccgtaa ctctattgaa
5101 agacaactct ggtggactcg cgggccaaat catgaggatc catttgagac actggttcca
5161 cactcacaga gaaaggtcca attaatatcc ttgctgggtg aagcagcact ccacggtgaa
5221 aaattctaca gaaagatagc tggtagagtc attcaagaag tcaaagaggg agggcttgaa
5281 atctacattc ctggttggca ggccatgttc cgctggatgc gattccatga tctaagtttg
5341 tggacaggag accgcgatct cctgcccgat tatgtaaatg atgatggcgt ctaaggacgc
5401 cccaacaaac atggatggca ccagtggtgc cggccagctg gtaccagagg caaatacagc
5461 tgagcctata tcaatggagc ccgtagctgg ggcagcgaca gctgccgcaa ctgctggcca
5521 agttaatatg attgacccct ggataatgaa taattatgta caagcccctc aaggtgaatt
5581 taccatatcg cccaacaata ctccgggtga tattttgttt gatttacaat tgggccccca
5641 ccttaacccc tttctgtctc atttggccca aatgtacaat ggctgggttg gcaatatgaa
5701 agtgaaggtt ctattggctg gtaatgcctt cacggctggt aaaataatta ttagttgcat
5761 accccctggc tttgctgcac aaaatatttc tatcgcccag gctactatgt ttccccatgt
5821 catagctgat gttagggttt tggaacccat tgaggtgcca ttggaagatg tgaggaatgt
5881 gctctttcac aacaatgata acacaccaac tatgcggttg gtgtgcatgc tctacacccc
5941 cttgcgggcc agtggtagct cgtctggaac tgaccccttt gtgattgctg ggcgtgtctt
6001 gacatgcccg agtcctgatt ttagtttctt gtttttggtc ccccccaatg tagagcaaaa
6061 gaccaaacct tttagtgtcc caaaccttcc attaaacact ctttcaaatt cgagagtccc
6121 ttctctaatc aagtcaatga tggtgtccag ggaccatggg cagatggttc agtttcaaaa
6181 tggcagggtc accctggatg ggcagttgca aggcaccaca ccaacgtcag ctagtcagct
6241 gtgcaaaatc aggggcaatg ttttccatgc caatggtggg aatgggtaca acctaacaga
6301 actggatggg agcccatacc atgcatttga gagccccgca ccaatagggt ttccagatct
6361 aggtgagtgt gattggcaca tggaggcttc tcctactacc caatttgata ctggagatgt
6421 cataaaacaa attaatgtca aacaagagtc agcatttgcc ccccaccttg gcactataca
6481 ggcagatggc ctgaatgatg tgagtgtcaa caccaacatg atagctaaat taggatgggt
6541 gtcacccgtc agtgatggac acaaaggtga tgttgacccg tgggtcatcc cacgctatgg
6601 ttcaactctg actgaggccg cccagttagc ccccccaata tatcccccag gcttcggtga
6661 ggccattgtg tttttcatgt cagattttcc tattgcccat ggcatcaatg gcttgagtgt
6721 gccttgcacc ataccccaag aatttgtcac tcactttgtc aacgaacagg cccctattag
6781 aggggaagca gccttgctac attatctgga ccctgatact catagaaatc ttggtgagtt
6841 taaattatac cctgatggct tcatgacatg tgtgcctaat tctagtggca ctggtccaca
6901 aactcttcca atcaatggtg tttttgtctt tgtgtcctgg gtttctagat tttatcaatt
6961 aaagcctgtg ggaacagccg gcccggctcg taggcttggg attaggagat cataatggct
7021 caagccatac ttggagccat agcagcaaca gcagccggta gtgctgttgg tgctggtata
7081 caagctggga ccgaagctgc cctacagcat caaagatttc agcaagattt gaccttacaa
7141 aagaattcct ttattcatga taaagagatg atgggcctac aggtagaggc ttcaactgca
7201 ctcctccaaa acagcttggg tacaaggtac aacatgttga ccaaggcagg gatgacatcc
7261 gcagacgcgg cacgtatggt agtgggggca cccgctactc gtgtcgttga ctggaacggt
7321 actaggatcg ccgcacccat gtcaactgcg acgacactta ggtctggtgg tttcatgacc
7381 gtaccaactg tttatagggg tagtaagaat aaacaatcag ttggtggtgg tttttctaat
7441 gtaaattatg atccctcagt ctcctcttct cgcacttctc aatgggtctc ttctcaaaat
7501 tcaatgcgtt ccactttgga accatttcat ccaggtgctt taaggactac atgggtcacc
7561 ccacctgggt caacctctac ttctacaatt tccacagttt ctactgtgcc aaaattcttc
7621 aatacagaaa ggttaccctt attcgcaaat aggggtaaat gatttttgta atatgaatta
7681 gtgggcatca tattcaattt ggaatcaatt agatatttag attggcagat gatgt
//