Typing tool
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Typing tool
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Complete norovirus genomes
| MT089578 | GI.3 | |
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| GI.P3 |
ORF1: 1..5393
ORF2: 5377..7014
ORF3: 7014..7661
LOCUS MT089578 7704 bp RNA linear VRL 01-MAY-2020
DEFINITION Norovirus GI isolate 461-1 nonstructural polyprotein (ORF1) gene,
partial cds; and VP1 (ORF2) and VP2 (ORF3) genes, complete cds.
ACCESSION MT089578
VERSION MT089578.1
DBLINK BioProject: PRJNA604000
KEYWORDS .
SOURCE Norovirus GI
ORGANISM Norovirus GI
Viruses; Riboviria; Orthornavirae; Pisuviricota; Pisoniviricetes;
Picornavirales; Caliciviridae; Norovirus; Norwalk virus.
REFERENCE 1 (bases 1 to 7704)
AUTHORS Yang,Z., Williams-Hill,D., Wolfe,J., Silva,A.J., Hirneisen,K.,
Ruelle,S., Kulka,M. and Hellberg,R.S.
TITLE Direct Submission
JOURNAL Submitted (13-FEB-2020) Molecular Virology Team/Devision of
Molecular Biology, OARSA/CFSAN/FDA, 8301 Muirkirk Rd., Laurel, MD
20708, USA
COMMENT ##Assembly-Data-START##
Assembly Method :: CLC Genonics Workbench v. 11
Sequencing Technology :: Illumina
##Assembly-Data-END##
FEATURES Location/Qualifiers
source 1..7704
/organism="Norovirus GI"
/mol_type="genomic RNA"
/isolate="461-1"
/isolation_source="stool"
/host="Homo sapiens"
/db_xref="taxon:122928"
/country="USA"
/collection_date="24-Jul-2019"
/note="genotype: GI.P3-GI.3"
gene <1..5393
/gene="ORF1"
CDS <1..5393
/gene="ORF1"
/codon_start=3
/product="nonstructural polyprotein"
/protein_id="QIC52022.1"
/translation="ASNDAIAVADVSNNNANTNNDNIGSRLMARIRGRIGPQRGETTT
KIKDANMALDLLRRSQTPSPSRQESPPKSQRDRPPRTASEVKKVLGWDVEPEHQESTA
KAWCDLTQEEKEEIMRNNEKLFDAGGITPSTLPSTFERADPVDSPTEQQPVTWSASGG
VDIGVNDLTTVRGPFWNMCPLPPLDARSNGPAKEPLIGDMIEFYEGHIFHYAIYIGQG
KTIGVHSPQAAFSIPRITIHPLVAWWRVCYVPNNQQRLTYDQLKELENEPWPYASITN
NCYEFCCRVMALDDTWLERRLVSTGKFNHPTQDWSQDTPDFHQDSKLEMVRDAVLSAI
NGLVSQPFRNILSKIKPLNVLNLLSNCDWTFMGVVELIVLLAELFDVFWTPPDISSFI
ASLLPEFHLQGPEDLARDLVPLILGGIGLAIGFTRDKITKVMKSAVDGLRSATQLGQY
GLEIFSIIKKYFFGGDQTEKTLRGIEDAVIDMEVLSSTNVTQLVKDKKLARTYMNVLD
NEEEKARKLSVRSADPHIVTSVNNLISRISMARSALAKAQAEMTSRPRPVVIMMCGPP
GIGKTKAAEHLAGRLANEIRPGGKVGLVPRESIDHWDGYHGEDVLLWDDYGMSKITED
CNKLQAIADTAPLSLNCDRIENKGMQFSSDAIIITTNAPGPAPVDFVNLGPVCRRVDF
LVYCSAPEIEQMRRTHPGDANAIKDLYKRDYSHLKMELAPQGGFDSQGNTPFGKGTMK
PTTLNRLLIQATALAMERQDEFQLQGAVYNFDEDRVSAFTSLARANGLGLLSMATLGK
RLRSVKSMEGLRNALVGYKIGECDIIWNTRVYSIKSDGSTVTIKEKQTPTSPQYQAIS
TATLALSRLRAARALAYASCLQSAVLSILQVAGSALVVSRAVKRMFGTRTEQPMLEGK
HKEHNCRVHRAEAAGHGPIGHDGVIERYGLCESEQEEEGEQIFELPTANKEGKNKGKT
KKGRGRKSNFNAFSRRGLSDEEYEEYKKIREEKSGNYSIQEYLEDRQRYEEELAEVQA
GGDGGIGETEAEIRHRVFYKSKSGMRKQRQEERRQLGLVSGSEIRKRKPIDWTPPKND
WSEDTRTVNYDEHISFEAPPSIWSRVVKFGSGWGFWVSSTVFITTTHVIPPGAKEVFG
EDLSNVAIHRVGEFTQFRFSKKMRPDLTGMVLEEGCPEGTVCTIMIKRDSGELLPLAV
RMGAVASMKIQGKLMHGQSGMLLTGANAKGMDLGTIPGDCGAPYVHKRGNDWVVCGVH
AAATKSGNTVVCAIQGGDGEATLEGGGQNKGHYAGHPILRYGNGPSLSTKTKFWKSTP
QPLPPGTYEPAYLGGRDPRVEGGPSLQQVLRDQLKPFAEPRGRLPEAGLLEAAVETVT
NAIEQVMDTPVAWSYSDACMSLDKTTSSGHPHHKKKNDDWNGNSFVRELGDQAALANS
MYELGKSMKPVYTAALKDELVKPDKVYTKIKKRLLWGADLGTVIRAARAFGPFCEAIK
PHVIKLPIKVGMNAIEDGPLIYAEHSKYKFHYDADYTAWDSTQNREIMMESFNIMCKL
TANPSLAAVVAQDLLSPSEMDVGDYVISVKDGLPSGFPCTSQVNSINHWILTLCALSE
VTGLSPDVIQSQSYFSFYGDDEIVSTDIEFDPIRLTQILKEYGLKPTRPDKTDGPIII
RQQVDGLVFLRRTISKDAIGYQGRLDRNSIERQLWWTRGPNHEDPFETLVPHSQRKVQ
LISLLGEAALHGEKFYRKIAGRVIQEVKEGGLEIYIPGWQAMFRWMRFHDLSLWTGDR
DLLPDYVNDDGV"
mat_peptide 3..1217
/gene="ORF1"
/product="p48"
mat_peptide 1218..2306
/gene="ORF1"
/product="NTPase"
mat_peptide 2307..2906
/gene="ORF1"
/product="p22"
mat_peptide 2907..3326
/gene="ORF1"
/product="VPg"
mat_peptide 3327..3869
/gene="ORF1"
/product="Pro"
mat_peptide 3870..5390
/gene="ORF1"
/product="RdRp"
gene 5377..7014
/gene="ORF2"
CDS 5377..7014
/gene="ORF2"
/note="major capsid protein"
/codon_start=1
/product="VP1"
/protein_id="QIC52023.1"
/translation="MMMASKDAPTNMDGTSGAGQLVPEANTAEPISMEPVAGAATAAA
TAGQVNMIDPWIMNNYVQAPQGEFTISPNNTPGDILFDLQLGPHLNPFLSHLAQMYNG
WVGNMKVKVLLAGNAFTAGKIIISCIPPGFAAQNISIAQATMFPHVIADVRVLEPIEV
PLEDVRNVLFHNNDNTPTMRLVCMLYTPLRASGSSSGTDPFVIAGRVLTCPSPDFSFL
FLVPPNVEQKTKPFSVPNLPLNTLSNSRVPSLIKSMMVSRDHGQMVQFQNGRVTLDGQ
LQGTTPTSASQLCKIRGNVFHANGGNGYNLTELDGSPYHAFESPAPIGFPDLGECDWH
MEASPTTQFDTGDVIKQINVKQESAFAPHLGTIQADGLNDVSVNTNMIAKLGWVSPVS
DGHKGDVDPWVIPRYGSTLTEAAQLAPPIYPPGFGEAIVFFMSDFPIAHGINGLSVPC
TIPQEFVTHFVNEQAPIRGEAALLHYLDPDTHRNLGEFKLYPDGFMTCVPNSSGTGPQ
TLPINGVFVFVSWVSRFYQLKPVGTAGPARRLGIRRS"
gene 7014..7661
/gene="ORF3"
CDS 7014..7661
/gene="ORF3"
/note="minor structural protein; small basic protein"
/codon_start=1
/product="VP2"
/protein_id="QIC52024.1"
/translation="MAQAILGAIAATAAGSAVGAGIQAGTEAALQHQRFQQDLTLQKN
SFIHDKEMMGLQVEASTALLQNSLGTRYNMLTKAGMTSADAARMVVGAPATRVVDWNG
TRIAAPMSTATTLRSGGFMTVPTVYRGSKNKQSVGGGFSNVNYDPSVSSSRTSQWVSS
QNSMRSTLEPFHPGALRTTWVTPPGSTSTSTISTVSTVPKFFNTERLPLFANRGK"
ORIGIN
1 tggcgtctaa cgacgctatt gccgttgctg atgtcagcaa taacaatgct aacaccaaca
61 atgataatat tggatcccgc ctcatggcga ggatccgtgg gcgcataggc ccacaacgtg
121 gtgaaacaac cacaaagata aaagacgcca atatggcgct tgatctgcta cgccggtcac
181 aaacaccctc cccatcccgg caagagagcc ctcctaagag ccaaagggac cgcccccctc
241 ggactgcttc tgaggtgaag aaagtattgg ggtgggatgt tgaaccagaa caccaggaaa
301 gcacggccaa ggcatggtgt gacctcacgc aggaagagaa ggaggagata atgcgcaata
361 atgaaaagct cttcgatgct gggggaatca ctccatcaac tttgcccagc acgtttgaaa
421 gggccgaccc agttgatagt cccactgaac agcaacctgt aacatggtct gctagtggcg
481 gggttgatat tggtgtcaat gacttgacca ctgtccgcgg cccattttgg aatatgtgcc
541 ccctcccacc attggatgct cggagtaatg gccccgccaa ggagcccctc ataggagaca
601 tgatagagtt ctatgagggt catatattcc attatgccat ctatattggg caaggtaaga
661 ccattggagt tcactcaccg caagcagctt tctccatacc aaggataacc atccatcccc
721 tggtagcctg gtggcgtgtg tgctacgttc caaataacca gcagcgcctc acttatgacc
781 aactgaaaga attggagaat gagccatggc cctatgcttc cattacaaac aattgttacg
841 agttctgctg cagggtgatg gcacttgacg acacatggct tgagaggaga ttggtcagca
901 ctggaaaatt caaccacccc acacaagact ggtcacagga taccccggat tttcaccaag
961 attcgaaact tgagatggtg agagatgcag tgctatcagc tattaatggc cttgtgtcac
1021 aaccctttag aaacatcttg tcaaagatca aaccattaaa tgttcttaat ctcttgtcaa
1081 actgtgattg gaccttcatg ggggttgtgg aactaatcgt gctcctagca gagctgtttg
1141 atgtgttctg gaccccacca gacatttcaa gtttcattgc ctcactacta cctgaatttc
1201 acctgcaggg tccagaagac ctagctaggg acttggtccc cctcatccta ggaggcatag
1261 gtttggctat tggctttaca agagacaaaa tcacgaaagt gatgaagagt gccgtcgatg
1321 ggctgagatc ggcgacacag cttgggcagt acggactgga aatattctca atcatcaaga
1381 agtatttctt tggtggggac caaacggaaa agaccttgcg gggtattgag gatgcagtga
1441 tagacatgga ggtattatct agcaccaatg tgacacaact ggttaaagac aagaaattgg
1501 ccagaaccta catgaatgtg ctagataatg aagaggaaaa agcaaggaaa ctctcagtcc
1561 gtagtgctga tccacacata gtgacctcag tcaacaatct gatatcacgg atatctatgg
1621 caagatcagc cttggccaaa gcccaggctg agatgacatc tcgcccacgc cctgtggtca
1681 taatgatgtg tggccccccc ggcattggaa aaaccaaggc cgctgaacat ctggctggcc
1741 gattggcgaa cgagattaga ccaggaggta aggttggact tgtgcctcgg gagtctatag
1801 atcattggga cggatatcat ggagaggatg tcctactatg ggacgactat ggcatgtcaa
1861 agataacaga ggactgtaac aagctacaag ccatagctga cactgcaccc ctatcactta
1921 attgtgacag gatagagaac aaaggtatgc aattctcctc agatgcaata attataacca
1981 ccaatgcccc cggcccagca ccggtggact ttgtcaacct aggccctgtg tgcaggcgag
2041 tggacttttt agtttactgt tctgcccccg aaattgaaca aatgagaagg acccaccctg
2101 gtgatgccaa tgccatcaaa gacctataca aaagggacta ttcacactta aaaatggagt
2161 tggccccaca aggtggtttt gatagtcagg gtaacacacc atttgggaag ggcaccatga
2221 aacccacgac cctcaacagg ctactcattc aggcaacagc attagctatg gagcggcaag
2281 atgagttcca gctccaaggg gctgtctaca attttgatga agatagggtg tccgccttca
2341 caagcctggc tcgagccaac ggcctggggc tcttaagcat ggcgacattg ggaaagaggc
2401 tcagaagtgt caagtctatg gagggcctgc gcaatgcatt ggtgggttac aaaataggag
2461 agtgtgatat aatctggaac actagagtgt attcaattaa aagtgatggt agtactgtca
2521 caatcaagga aaaacaaacc ccaacttcac ctcaatatca ggccattagc acagccactc
2581 ttgcactctc tagattgcgg gccgctagag ctctcgcgta cgcctcctgc ctgcagagtg
2641 cagtgctgtc aatacttcaa gtagctggct ctgccctggt ggtgagcaga gccgttaagc
2701 gcatgtttgg cactcgcact gaacaaccta tgttggaagg caagcacaaa gaacataact
2761 gcagagtgca ccgcgcagag gcagctggcc atggtcctat tggacacgat ggagtcatcg
2821 aacgctatgg cctttgtgag agtgagcaag aagaagaagg cgagcaaatt tttgagttac
2881 ccactgccaa taaagaaggt aaaaacaagg gcaagaccaa aaagggccgt ggacgaaaat
2941 ccaattttaa cgctttctca agacgaggcc tcagtgatga agagtatgaa gaatacaaga
3001 agatcagaga agaaaagagt ggtaattaca gcatccagga gtaccttgag gaccgccaac
3061 gatatgagga agaacttgct gaagtgcagg ctggtggaga tggtggaatt ggtgagactg
3121 aagcagagat tcgccatcgg gtcttctata aatcaaaatc tggtatgaga aagcaacgcc
3181 aagaagaacg gcgtcagttg ggcctcgtta gcggttctga gattcgcaaa cgcaagccca
3241 tagactggac cccccctaag aatgactggt cagaagacac caggactgtc aattatgatg
3301 aacacattag ctttgaagcc cctccctcaa tttggagtag ggtggtaaag tttggcagtg
3361 gttggggttt ttgggtgagc tcaacagtgt tcataaccac aacccatgtt ataccacctg
3421 gggctaaaga agtctttggt gaagacctca gtaatgtggc catccataga gttggtgagt
3481 ttacccagtt ccgtttctcc aaaaagatga gacctgacct cactggtatg gtcttagaag
3541 aaggttgccc agagggaaca gtgtgtacca taatgattaa gagagattct ggtgagttgc
3601 tgccgctcgc cgttcgaatg ggggcagtgg catcaatgaa gatccaaggc aaacttatgc
3661 atgggcaatc aggaatgtta ctcaccggtg ctaatgccaa gggcatggac cttggaacta
3721 tacccggtga ttgtggggca ccctatgtcc acaagagggg aaacgactgg gtggtctgtg
3781 gagtacatgc agccgccaca aaatcaggca acactgtggt gtgcgccata cagggtggcg
3841 atggtgaagc cactctggag ggtggcggtc aaaacaaggg ccactatgca gggcatccga
3901 tactaaggta tgggaatggc ccttcgctat caaccaaaac aaaattttgg aagtcaaccc
3961 cccagccttt gccccctggt acatatgagc cagcttacct tggaggcaga gatcccagag
4021 ttgagggggg cccatcctta caacaggtgt taagggacca gttaaagcca tttgccgagc
4081 cccgtggcag attgcccgaa gcaggcttgt tggaagctgc agttgagacg gtcaccaatg
4141 ccattgaaca ggtcatggac acaccggtgg catggagcta cagcgatgct tgcatgtccc
4201 tggataagac aaccagttcc ggccatcccc atcacaagaa gaaaaatgat gactggaatg
4261 ggaattcatt tgtgagagaa ttgggcgacc aggcggcgct tgctaacagc atgtacgagc
4321 ttggtaagtc catgaaacca gtgtatacag cagccctaaa ggatgagctg gtcaaaccag
4381 acaaggtgta cacaaaaatc aaaaagagac tgctttgggg cgcggacctt ggtaccgtca
4441 tccgcgctgc cagagcattt ggaccatttt gtgaagccat aaaaccccat gtaattaagc
4501 tgcctatcaa ggtgggtatg aatgccatag aggacggccc tttgatttat gcagagcact
4561 ccaaatataa atttcattat gatgctgact acacagcttg ggattcaaca caaaatagag
4621 aaatcatgat ggaatctttc aacattatgt gtaagctcac agccaatccc tcccttgccg
4681 cagtggtggc gcaggatcta ctctccccat ctgaaatgga tgttggtgat tatgtgatca
4741 gtgtcaaaga tggtttgcca tcaggctttc cgtgcacctc acaggtgaac agtatcaacc
4801 attggattct aaccctgtgc gctctgtcag aagtcactgg cttgtcccca gatgtgatac
4861 agtcacaatc ctacttctca ttttatggtg atgatgaaat agtctcaaca gacatagaat
4921 ttgacccaat taggttgaca caaatactga aggaatatgg tctgaagcct acaagacctg
4981 acaaaactga tggcccaatt attatcagac agcaggttga tggtctggtc tttctccggc
5041 gcaccatttc taaggatgcc attggatacc agggacgact cgaccgtaac tctattgaaa
5101 gacaactctg gtggactcgc gggccaaatc atgaggatcc atttgagaca ctggttccac
5161 actcacagag aaaggtccaa ttaatatcct tgctgggtga agcagcactc cacggtgaaa
5221 aattctacag aaagatagct ggtagagtca ttcaagaagt caaagaggga gggcttgaaa
5281 tctacattcc tggttggcag gccatgttcc gctggatgcg attccatgat ctaagtttgt
5341 ggacaggaga ccgcgatctc ctgcccgatt atgtaaatga tgatggcgtc taaggacgcc
5401 ccaacaaaca tggatggcac cagtggtgcc ggccagctgg taccagaggc aaatacagct
5461 gagcctatat caatggagcc cgtagctggg gcagcgacag ctgccgcaac tgctggccaa
5521 gttaatatga ttgacccctg gataatgaat aattatgtac aagcccctca aggtgaattt
5581 accatatcgc ccaacaatac tccgggtgat attttgtttg atttacaatt gggcccccac
5641 cttaacccct ttctgtctca tttggcccaa atgtacaatg gctgggttgg caatatgaaa
5701 gtgaaggttc tattggctgg taatgccttc acggctggta aaataattat tagttgcata
5761 ccccctggct ttgctgcaca aaatatttct atcgcccagg ctactatgtt tccccatgtc
5821 atagctgatg ttagggtttt ggaacccatt gaggtgccat tggaagatgt gaggaatgtg
5881 ctctttcaca acaatgataa cacaccaact atgcggttgg tgtgcatgct ctacaccccc
5941 ttgcgggcca gtggtagctc gtctggaact gacccctttg tgattgctgg gcgtgtcttg
6001 acatgcccga gtcctgattt tagtttcttg tttttggtcc cccccaatgt agagcaaaag
6061 accaaacctt ttagtgtccc aaaccttcca ttaaacactc tttcaaattc gagagtccct
6121 tctctaatca agtcaatgat ggtgtccagg gaccatgggc agatggttca gtttcaaaat
6181 ggcagggtca ccctggatgg gcagttgcaa ggcaccacac caacgtcagc tagtcagctg
6241 tgcaaaatca ggggcaatgt tttccatgcc aatggtggga atgggtacaa cctaacagaa
6301 ctggatggga gcccatacca tgcatttgag agccccgcac caatagggtt tccagatcta
6361 ggtgagtgtg attggcacat ggaggcttct cctactaccc aatttgatac tggagatgtc
6421 ataaaacaaa ttaatgtcaa acaagagtca gcatttgccc cccaccttgg cactatacag
6481 gcagatggcc tgaatgatgt gagtgtcaac accaacatga tagctaaatt aggatgggtg
6541 tcacccgtca gtgatggaca caaaggtgat gttgacccgt gggtcatccc acgctatggt
6601 tcaactctga ctgaggccgc ccagttagcc cccccaatat atcccccagg cttcggtgag
6661 gccattgtgt ttttcatgtc agattttcct attgcccatg gcatcaatgg cttgagtgtg
6721 ccttgcacca taccccaaga atttgtcact cactttgtca acgaacaggc ccctattaga
6781 ggggaagcag ccttgctaca ttatctggac cctgatactc atagaaatct tggtgagttt
6841 aaattatacc ctgatggctt catgacatgt gtgcctaatt ctagtggcac tggtccacaa
6901 actcttccaa tcaatggtgt ttttgtcttt gtgtcctggg tttctagatt ttatcaatta
6961 aagcctgtgg gaacagccgg cccggctcgt aggcttggga ttaggagatc ataatggctc
7021 aagccatact tggagccata gcagcaacag cagccggtag tgctgttggt gctggtatac
7081 aagctgggac cgaagctgcc ctacagcatc aaagatttca gcaagatttg accttacaaa
7141 agaattcctt tattcatgat aaagagatga tgggcctaca ggtagaggct tcaactgcac
7201 tcctccaaaa cagcttgggt acaaggtaca acatgttgac caaggcaggg atgacatccg
7261 cagacgcggc acgtatggta gtgggggcac ccgctactcg tgtcgttgac tggaacggta
7321 ctaggatcgc cgcacccatg tcaactgcga cgacacttag gtctggtggt ttcatgaccg
7381 taccaactgt ttataggggt agtaagaata aacaatcagt tggtggtggt ttttctaatg
7441 taaattatga tccctcagtc tcctcttctc gcacttctca atgggtctct tctcaaaatt
7501 caatgcgttc cactttggaa ccatttcatc caggtgcttt aaggactaca tgggtcaccc
7561 cacctgggtc aacctctact tctacaattt ccacagtttc tactgtgcca aaattcttca
7621 atacagaaag gttaccctta ttcgcaaata ggggtaaatg atttttgtaa tatgaattag
7681 tgggcatcat attcaatttg gaat
//