Typing tool
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Typing tool
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Complete norovirus genomes
| MN588299 | GII.4 Sydney | |
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| GII.P31 |
ORF1: 5..5104
ORF2: 5085..6707
ORF3: 6707..7513
LOCUS MN588299 7545 bp RNA linear VRL 01-JAN-2021
DEFINITION Norovirus GII isolate HNV1 nonstructural polyprotein (ORF1), VP1
(ORF2), and VP2 (ORF3) genes, complete cds.
ACCESSION MN588299
VERSION MN588299.1
KEYWORDS .
SOURCE Norovirus GII
ORGANISM Norovirus GII
Viruses; Riboviria; Orthornavirae; Pisuviricota; Pisoniviricetes;
Picornavirales; Caliciviridae; Norovirus; Norwalk virus.
REFERENCE 1 (bases 1 to 7545)
AUTHORS Zhao,Y.L., sun,Q.M. and Zhang,L.S.
TITLE Whole-Genome Sequences of Human Norovirus GII.4 Variants Isolated
in Kunming,China
JOURNAL Unpublished
REFERENCE 2 (bases 1 to 7545)
AUTHORS Zhao,Y.L., sun,Q.M. and Zhang,L.S.
TITLE Direct Submission
JOURNAL Submitted (20-OCT-2019) Yunnan Key Laboratory of Vaccine Research &
Development on Severe Infectious Diseases, Institute of Medical
Biology, Chinese Academy of Medical Sciences and Peking Union
Medical College, 935 Jiao Ling Road, Kunming, Yunnan Province
650118, China
COMMENT ##Assembly-Data-START##
Sequencing Technology :: Sanger dideoxy sequencing
##Assembly-Data-END##
FEATURES Location/Qualifiers
source 1..7545
/organism="Norovirus GII"
/mol_type="genomic RNA"
/isolate="HNV1"
/isolation_source="feces"
/host="Homo sapiens"
/db_xref="taxon:122929"
/country="China"
/collection_date="20-Jul-2019"
/note="genotype: GII.4"
gene 5..5104
/gene="ORF1"
CDS 5..5104
/gene="ORF1"
/codon_start=1
/product="nonstructural polyprotein"
/protein_id="QFQ66976.1"
/translation="MKMASNDASAAAVANSNNDIAKSSSDGVFSSMAVTFKRALGARP
KQPPPKEIPPRPPRPPTPELVKKIPLPPPNGEDELVVSYNAKDGVSGLPELTTVRQPE
EANTAFSVPPLNQRESRDAKEPLTGTIIEMWDGEIYHYGLYVERGLILGVHKPPAAIS
FAKVELAPLSLFWRPVYTPQYLISPDTLRRLHGESFPYTAFDNNCYAFCCWVLDLNDS
WLSRRMIQRTTGFFRPYQDWNRKPLPTMDDSKLKKVANIFLCTLSSLFTRPIKDIIGK
LKPLNILNILATCDWTFAGIVESLILLAELFGVFWTPPDVSAMIAPLLGDYELQGPED
LAVELVPIVMGGIGLVLGFTKEKIGKMLSSAASTLRACKDLGAYGLEILKLVMKWFFP
KKEEANELAMVRSIEDAVLDLEAIENNHMTTLLKDKDSLTTYMRTLDLEEEKARKLST
KSASPDIVGTINSLLARIAAARSLVHRAKEELSSRPRPVVVMISGRPRIGKTHLAREL
AKKIAASLTGDQRVGLIPRNGVDHWDAYKGERVVLWDDYGMSNPIHDALRLQELADTC
PLTLNCDRIENKGKVFDSDAIIITTNLANPAPLDYVNFEACSRRIDFLVYAEAPEVEK
AKRDFPGQPDMWKNAFSPDFSHIKLSLAPQGGFDKNGNTPHGKGVMKTLTTGSLIARA
SGLLHERLDEYELQGPALTTFNFDRNKILAFRQLAAENKYGLMDTMRVGKQLKDVKTM
SDLKQALKNIAIKKCQIVYNGGTYTLEADGKGSVKVDKVQSATVQTNNELAGALHHLR
CARIRYYVKCVQEALYSIIQIAGAAFVTTRIAKRMNIQNLWSKPQVEDTEEMANKDGC
LIPKDGEEFVVSSDDIKTEGKKGKNKSGRGKKHTAFSSKGLSDEEYDEYKRIREERNG
KYSIEEYLQDRDRYYEEVAIARATEEDFCEEEEAKIRQRIFRPTRKQRKEERASLGLV
TGSEIRKRNPEDFKPKGKLWADDDRSVDYNEKLNFEAPPSVWSRIVNFGSGWGFWVSP
SLFITSTHVIPQGAKEFFGVPIKQIQIHKSGEFCRLRFPKPIRTDVTGMILEEGAPEG
TVATLLIKRPTGELMPLAARMGTHATMKIQGRTVGGQMGMLLTGSNAKSMDLGTTPGD
CGCPYIYKRGNDYVVIGVHTAAARGGNTVICATQGSEGEATLEGGDSKGTYCGAPILG
PGSAPKLSTKTKFWRSSTTPLPPGTYEPAYLGGKDPRVKGGPSLQQVMRDQLKPFTEP
RGKTPRPNVLEAAKKTIINVLEQTIDPPQKWSFAQACASLDKTTSSGHPYHMRKNDCW
NGESFTGKLADQASKANLMFEEGKNMIPVYTGALKDELVKTDKVYGKVKKRLLWGSDL
ATMVRCARAFGGLMDELKAHCVTLPVRVGMNMNEDGPIIFEKHSRYRYHYDADYSRWD
STQQRDVLAAALEIMVKFSPEPHLAQIVAEDLLSPSVMDVGDFQISISEGLPSGVPCT
SQWNSIAHWLLTLCALSEVTDLSPDIIQANSLFSFYGDDEIVSTDIKLDPERLTAKLK
EYGLKPTRPDKTEGPLVISEDLDGLTFLRRTVTRDPAGWFGKLEQSSILRQMYWTRGP
NHEDPFETMIPHSQRPIQLMSLLGEAALHGPAFYSKISKLVIAELKEGGMDFYVPRQE
PMFRWMRFSDLSTWEGDRNLAPSFVNEDGVE"
mat_peptide 5..994
/gene="ORF1"
/product="p48"
mat_peptide 995..2092
/gene="ORF1"
/product="NTPase"
mat_peptide 2093..2629
/gene="ORF1"
/product="p22"
mat_peptide 2630..3028
/gene="ORF1"
/product="VPg"
mat_peptide 3029..3571
/gene="ORF1"
/product="Pro"
mat_peptide 3572..5101
/gene="ORF1"
/product="RdRp"
gene 5085..6707
/gene="ORF2"
CDS 5085..6707
/gene="ORF2"
/note="major capsid protein"
/codon_start=1
/product="VP1"
/protein_id="QFQ66977.1"
/translation="MKMASSDVNPSDGSAANSVPEVNNEVMALEPVVGAAIAAPVAGQ
QNVIDPWIRNNFVQAPGGEFTVSPRNAPSEILWSAPLGPDLNPYLSHLARMYNGYASG
FEVQVILAGNAFTAGKVIFAAVPPNFPTEGLSPSQVTMFPHIVVDVRQLEPVLIPLPD
VRNNFYHYNQSNDPTIKLIAMLYTPLRANNAGDDVFTVSCRVLTRPSPDFDFIFLVPP
TVESRTKPFSVPVLTVEEMTNSRFPIPLEKLFTGPSSAFVVQPQNGRCTTDGVLLGTT
QLSPVNICTFRGDVTHTTGSHNYTMNLASQNWSNYDPTEEIPAPLGTPDFVGKIQGML
TQTTRTDGSTRGHKATVYTGSADFAPKLGRVQFETDTNNDFEANQNTKFTPVGVIQDG
GTTHRNEPQQWVLPSYSGRNTPNVHLAPAVAPTFPGEQLLFFRSTIPGCSGYPNMDLD
CLLPQEWVQYFYQEAAPAQSDVALLRFVNPDTGRVLFECKLHKSGYVTVAHTGQHDLV
IPPNGYFRFDSWVNQFYTLAPMGNGAGRRRAL"
gene 6707..7513
/gene="ORF3"
CDS 6707..7513
/gene="ORF3"
/note="minor structural protein; small basic protein"
/codon_start=1
/product="VP2"
/protein_id="QFQ66978.1"
/translation="MAGAFFAGLASDVLGSGLGSLINAGAGAINQKVEFENNRKLQQA
SFQFSSNLQQASFQHDKEMLQAQIEATKRLQQEMMKVKQAMLLEGGFSETDAARGAIN
APMTKALDWSGTRYWAPDARITTYNAGRFSTPQPSGAPPGRANFRDAVPARGSSSKSS
NSSTATSVYSNQTTSTRLGSTAGSGTSVSSFPSTARTRSWVEDQSRNLSPFMRGAHNI
SFVTPPSSRSSSQGTVSTVPKEILDSWTGAFNTRRQPLFAHIRKRGESRA"
ORIGIN
1 gtgaatgaag atggcgtcta acgacgcttc cgctgccgct gttgccaaca gcaacaacga
61 catcgcaaaa tcttcaagtg acggtgtgtt ttctagcatg gctgtcactt ttaagcgggc
121 cctcggggcg cggcctaaac agccgccccc gaaggaaata ccacccagac ccccgcgacc
181 acccacacca gaattggtca aaaagatccc tcttccccca cccaacgggg aggatgaact
241 agtggtctct tacaacgcca aagatggcgt ttccggactg cctgagctca ccactgtcag
301 acaaccggaa gaagccaaca cggcgttcag tgtcccccca ctcaaccaaa gggagagcag
361 ggacgctaag gagccactaa ctggaacaat cattgaaatg tgggatggag aaatctacca
421 ttacggcctg tacgtggaac gaggtcttat acttggtgtg cataagccgc cagcagccat
481 tagcttcgct aaggtcgagc tggcaccgct ctctttgttc tggagacctg tatacacccc
541 ccagtacctt atctctccag acactcttag gagattacat ggagagtcat tcccctacac
601 tgcatttgac aacaattgct acgccttttg ttgttgggta ttagacctaa acgactcatg
661 gctaagcagg agaatgattc agagaacaac aggcttcttc aggccgtacc aggattggaa
721 caggaaaccc ctccccacta tggatgattc caaattaaag aaggtagcca acatattctt
781 gtgcactttg tcttcactat tcaccaggcc cattaaggac ataataggga agttgaaacc
841 tctcaacatc cttaatattc tggctacatg tgattggacc ttcgcaggca tagtggaatc
901 cttaatactc ttagcagaac tctttggagt tttctggaca cccccagatg tgtctgcgat
961 gatcgcccca ttgctaggtg attatgaact gcaaggaccc gaggaccttg cagtggaact
1021 ggtcccaata gtgatggggg ggataggttt ggtgctagga tttaccaaag agaagatcgg
1081 aaagatgctg tcatccgctg catccacttt aagagcttgt aaagaccttg gtgcatacgg
1141 actggaaatc ttaaaattgg tcatgaagtg gttcttccca aagaaagagg aagcaaacga
1201 actggctatg gtgagatcta tcgaggatgc agtactagat ctcgaggcaa ttgaaaacaa
1261 ccacatgacc accctgctca aagacaaaga cagcttgaca acctacatga gaacccttga
1321 ccttgaggag gagaaagcca gaaagctctc aaccaaatct gcttcacccg atattgtggg
1381 tacaattaac tctcttctgg caagaatcgc tgctgcacgc tccctagtgc accgggcgaa
1441 agaagagctc tccagcaggc cgagacctgt cgttgtaatg atatcgggaa gaccacggat
1501 agggaaaact caccttgcca gggagctggc caagaagatc gcggcctccc tcacagggga
1561 ccagcgtgtg ggccttatcc cacgcaatgg tgtcgaccac tgggacgcat acaagggcga
1621 aagggttgtc ctatgggacg actatggaat gagcaacccc atccatgatg cccttaggtt
1681 gcaggaactt gctgacactt gccccctcac gctaaattgt gacagaattg agaacaaagg
1741 aaaagtcttt gacagtgatg ccataattat caccaccaac ctggccaacc cagcaccact
1801 ggattatgtc aactttgaag cgtgctcgag acgcattgat ttcctcgtgt acgcagaagc
1861 ccctgaagtg gagaaggcaa agcgcgactt cccaggtcaa cctgacatgt ggaagaacgc
1921 cttcagtcct gacttctcac acataaaact gtcattggct ccacagggtg gttttgacaa
1981 gaacggcaac accccgcatg gaaaaggggt catgaagacc ctcaccactg gctccctcat
2041 cgctcgagca tcagggttac tccatgagag gctagatgaa tatgaattgc aaggcccagc
2101 cctcaccact ttcaactttg accgcaacaa gatacttgct tttagacagc ttgctgctga
2161 aaacaagtat gggctgatgg acacaatgag agttggaaaa cagctcaagg atgtcaagac
2221 tatgtcagac ctcaaacaag cactcaagaa catcgcgatc aagaagtgcc agatagtgta
2281 caatggtggc acctacacac ttgaggctga tggcaagggc agtgtgaaag ttgacaaagt
2341 gcaaagtgcc actgtgcaga ccaacaatga actagccggt gctctacacc acctaagatg
2401 cgctagaatc agatactatg ttaagtgcgt ccaggaggca ctgtattcca tcatccaaat
2461 cgctggggct gcattcgtca ccacgcgcat cgctaagcgc atgaatatac agaatctctg
2521 gtccaagcca caggtggaag acacagaaga gatggccaac aaagatggtt gcctaatacc
2581 caaagatggt gaagagtttg tcgtttcatc cgacgacatc aaaactgagg gcaagaaagg
2641 gaagaacaag tccggccgtg gcaagaagca cacagccttt tcaagtaaag ggctcagtga
2701 tgaggagtac gatgagtaca agagaatcag agaagaaagg aatggtaagt actccataga
2761 agagtacctt caggacagag acaggtacta cgaggaggtg gccattgcca gggcaaccga
2821 agaggacttc tgtgaagaag aagaggccaa aatccggcag aggattttca gaccaacaag
2881 gaaacaacgc aaagaagaga gggcttctct cggcttggtc acaggctctg aaatcaggaa
2941 gagaaaccca gaagacttca aacccaaggg aaagctgtgg gctgatgacg acagaagtgt
3001 tgactacaat gagaaactca actttgaggc cccaccaagc gtctggtcgc ggatagtcaa
3061 ctttggttca ggctggggct tctgggtctc ccccagtctg tttataacat caacccatgt
3121 cataccccaa ggtgcaaagg agttcttcgg agtccctatc aagcaaatcc agatacacaa
3181 gtcaggtgaa ttctgccgat tgagattccc aaagccaatc agaaccgatg tgacgggcat
3241 gattctagaa gaaggtgcgc ccgaggggac cgtggccaca ctgctcatca agagaccaac
3301 tggagagctc atgcctctgg cagccagaat ggggacccat gcaaccatga aaattcaggg
3361 gcgcacagtt ggagggcaaa tgggtatgct cctgacagga tccaacgcca agagtatgga
3421 cctaggcaca acaccaggcg actgcggctg cccctacatc tacaagaggg ggaatgacta
3481 cgtggtcata ggggtccata cggctgctgc ccgtggagga aacactgtca tatgtgccac
3541 ccagggaagt gagggagagg ccacacttga aggaggtgac agtaaaggga catactgtgg
3601 cgcgccaatc ttgggcccag ggagcgctcc gaagctcagc accaagacta aattttggag
3661 atcatccaca acaccactcc cacctggcac ctacgaacca gcctacctcg gtggcaaaga
3721 ccctagagtc aaaggtggcc cttcattgca acaagttatg agggaccagc tgaagccatt
3781 cacagaaccc agaggcaaaa caccaagacc aaatgtgttg gaagctgcca agaaaaccat
3841 catcaatgtt cttgagcaaa caattgatcc accccaaaaa tggtcatttg cgcaagcttg
3901 tgcatccctt gataaaacca cctccagcgg ccacccgtac cacatgcgga aaaacgactg
3961 ttggaatggg gagtccttca caggaaagtt ggctgaccaa gcctccaagg ccaacctaat
4021 gtttgaagag ggaaagaaca tgattccagt ctacacaggt gcacttaaag atgagttagt
4081 aaagactgat aaagtttatg gtaaggtcaa gaagaggctt ctatggggtt cagatctggc
4141 gaccatggta cggtgcgccc gagcttttgg aggcctcatg gatgaactca aggcacactg
4201 tgtcacactc cctgtcagag ttggtatgaa catgaatgag gatggcccca tcatcttcga
4261 gaagcactcc agatatagat atcattatga tgctgactat tcccggtggg actcaacaca
4321 acaaagggat gtgctggcag cagcactaga aatcatggtt aagttctctc cagaaccaca
4381 cctggcccag atagttgcag aagacctcct ttcccctagc gtgatggatg tgggtgactt
4441 tcaaatatca ataagtgagg gtctcccctc tggggtgcct tgcacctccc agtggaattc
4501 catcgcccac tggctcctca ctctgtgtgc actctctgaa gtcacggacc tgtcccctga
4561 tatcattcag gccaactccc ttttctcctt ctatggtgat gatgagattg taagcacaga
4621 cataaagttg gacccagaga ggctaacagc aaaactcaag gagtacgggc tgaaaccaac
4681 ccgccccgac aaaactgaag gaccccttgt catctctgaa gacctggatg gtctgacatt
4741 cctccggaga actgtgaccc gtgatccagc tggctggttt ggaaaattgg aacaaagttc
4801 aattcttagg caaatgtact ggaccagggg tcccaaccat gaagacccat ttgaaacaat
4861 gataccacac tcccaaagac ccatacaatt gatgtccttg ctgggcgagg ctgcactcca
4921 cggcccggca ttctacagca aaattagcaa attagtcatt gcagagttga aggaaggtgg
4981 catggatttt tacgtaccca gacaagagcc aatgttcaga tggatgagat tctcagatct
5041 gagcacgtgg gagggcgatc gcaatctggc tcccagtttt gtgaatgaag atggcgtcga
5101 gtgacgtcaa cccatctgat gggtccgcag ccaactccgt cccagaggtc aacaatgagg
5161 ttatggctct ggagccggtt gttggtgccg ccattgcggc acctgtagcg ggccaacaaa
5221 atgtaattga cccctggatt agaaacaatt ttgtacaagc ccctggtgga gagtttacag
5281 tatcccctag aaacgctcca agtgaaatac tatggagcgc gcccttgggc cctgatctaa
5341 atccctactt gtctcatttg gccagaatgt acaatggtta tgcaagtggt tttgaagtgc
5401 aggtaattct cgcggggaac gcgttcaccg ccgggaaggt catatttgca gcagtcccac
5461 caaattttcc aactgaaggc ttgagcccca gccaggtcac tatgttcccc catatagtag
5521 tagatgttag gcaactagaa cctgtgttga ttcccttacc cgatgttagg aataatttct
5581 atcattacaa tcaatcaaat gaccccacca ttaagttgat agcaatgttg tatacaccac
5641 ttagggctaa taatgctggg gatgatgtct tcacagtttc ttgccgagtt ctcacgagac
5701 catcccccga ttttgacttc atatttctag tgccacccac agttgagtca agaactaaac
5761 cattctctgt cccagttttg actgttgagg agatgaccaa ttcaagattc cccattcctt
5821 tggaaaagtt gttcacgggt cccagcagtg cctttgttgt ccaaccacaa aatggtaggt
5881 gcacgactga tggcgtgctc ctaggcacca cccaactgtc tcctgtcaac atctgcacct
5941 ttagaggaga tgtcacccat accacaggta gtcacaacta tacaatgaat ttggcttctc
6001 aaaattggag taactacgac ccaacagaag aaatcccagc ccctctaggg actccagact
6061 ttgtggggaa gattcaaggc atgcttaccc aaaccacaag gacagatggc tcaacacgcg
6121 gccacaaagc cacagtgtat actgggagcg ccgactttgc tccaaaactg ggtagagttc
6181 aatttgaaac tgacacaaac aatgattttg aagctaacca aaacacaaag ttcaccccag
6241 ttggtgtcat ccaagatggt ggcaccactc atcgaaatga accccaacag tgggtgctcc
6301 caagttactc aggcaggaac actcctaatg tgcatctggc ccccgctgtg gcccccactt
6361 ttccgggtga gcaactcctc ttctttagat ccaccatacc cggatgcagc gggtacccca
6421 acatggattt ggattgtctg ctcccccagg aatgggtgca gtacttctac caggaggcag
6481 ccccagcaca atctgatgtg gctctgctaa gatttgtgaa tccagacaca ggtagggttt
6541 tgtttgaatg taagcttcac aaatcaggct atgttacagt ggcccacact ggccaacatg
6601 atttggttat cccccccaat ggttatttta ggtttgattc ctgggtcaat cagttttaca
6661 cgcttgcccc catgggaaat ggagcggggc gtagacgtgc actataatgg ctggagcttt
6721 ctttgctgga ttggcttctg atgtccttgg ctctggactt ggttccctta tcaatgctgg
6781 ggctggggcc atcaaccaaa aagttgagtt tgaaaataat agaaaattgc agcaagcatc
6841 cttccaattt agcagcaatc tacaacaggc ttcctttcaa catgacaaag agatgctcca
6901 agcacaaatt gaggctacca aaaggttaca acaggaaatg atgaaagtta agcaggcaat
6961 gctcctagag ggtgggttct ctgagacaga tgcagcccgc ggggcaatca acgcccctat
7021 gacaaaagcc ttggactgga gcgggacaag gtactgggct cctgatgcta ggattacaac
7081 atacaatgca ggccgctttt ccacccccca accatcgggg gcgccgccag gaagagctaa
7141 ttttagggat gctgtccctg ctcggggttc ctctagtaag tcttctaatt cttctactgc
7201 tacttctgtg tattcaaatc aaactacttc aacgagactt ggttctacag ctggttctgg
7261 taccagtgtc tcgagtttcc cgtcaactgc aaggactagg agctgggttg aggaccaaag
7321 taggaatttg tcacctttca tgaggggggc ccacaacata tcgtttgtca ccccaccatc
7381 tagcaggtcc tctagccaag gcacagtctc aaccgtgcct aaagagattt tggactcctg
7441 gactggcgct ttcaacacgc gcaggcagcc actcttcgct cacattcgta agcgagggga
7501 gtcacgggcg taatgtgaaa agacaaaatt gattatcttt ctttc
//