Typing tool
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Typing tool
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Complete norovirus genomes
| MN308019 | GII.4 Sydney | |
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| GII.P31 |
ORF1: 1..5103
ORF2: 5084..6706
ORF3: 6706..7512
LOCUS MN308019 7512 bp RNA linear VRL 29-JUN-2021
DEFINITION Norovirus GII isolate 181_GII.Pe_GII.4_Araguaina nonstructural
polyprotein (ORF1), VP1 (ORF2), and VP2 (ORF3) genes, complete cds.
ACCESSION MN308019
VERSION MN308019.1
KEYWORDS .
SOURCE Norovirus GII
ORGANISM Norovirus GII
Viruses; Riboviria; Orthornavirae; Pisuviricota; Pisoniviricetes;
Picornavirales; Caliciviridae; Norovirus; Norwalk virus.
REFERENCE 1 (bases 1 to 7512)
AUTHORS Tinker,R.J., da Costa,A.C., Tahmasebi,R., Milagres,F.A.P., Dos
Santos Morais,V., Pandey,R.P., Jose-Abrego,A., Brustulin,R.,
Rodrigues Teles,M.D.A., Cunha,M.S., Araujo,E.L.L., Gomez,M.M.,
Deng,X., Delwart,E., Sabino,E.C., Leal,E. and Luchs,A.
TITLE Norovirus strains in patients with acute gastroenteritis in rural
and low-income urban areas in northern Brazil
JOURNAL Arch Virol 166 (3), 905-913 (2021)
PUBMED 33462673
REFERENCE 2 (bases 1 to 7512)
AUTHORS Tinker,R.J., da-Costa,A.C., Leal,E.S., Tahmasebi,R.,
Milagres,F.A.P., Pandey,R.P., Jose-Abrego,A., Brustulin,R.,
Teles,Md.A.R., Sayao-Lobato,M.C.A.B., Chagas,R.T.,
Santos-Abrao,Md.F.N., Alves-Soares,C.V.D., Cunha,M.S., Deng,X.,
Delwart,E., Sabino,E.C. and Luchs,A.
TITLE Direct Submission
JOURNAL Submitted (13-AUG-2019) Institute of Tropical Medicine, University
of Sao Paulo, Av Dr Eneas de Carvalho Aguiar 470, Sao Paulo, Sao
Paulo 05403000, Brazil
COMMENT ##Assembly-Data-START##
Assembly Method :: Geneious v. R9
Sequencing Technology :: Illumina
##Assembly-Data-END##
FEATURES Location/Qualifiers
source 1..7512
/organism="Norovirus GII"
/mol_type="genomic RNA"
/isolate="181_GII.Pe_GII.4_Araguaina"
/isolation_source="feces"
/host="Homo sapiens"
/db_xref="taxon:122929"
/country="Brazil"
/collection_date="06-Aug-2014"
/note="genotype: GII.Pe_GII.4"
gene 1..5103
/gene="ORF1"
CDS 1..5103
/gene="ORF1"
/codon_start=1
/product="nonstructural polyprotein"
/protein_id="QED42445.1"
/translation="MKMASNDASAAAVANSNNDIAKSSSDGVFSNMAVTFKRPLGARP
KQPPPKEIPPRPPRPPTPELGKKIPPPPPNGEDELVVSYSAKDGVSGLPELTTVRQPE
ETNTAFSVPPLNQRESRDAKEPLTGTIIEMWDGEIYHYGLYVERGLILGVHKPPAAIS
LAKVELTPLSLFWRPVYTPQYLISPYTLRSLHCDSFPYTAFYNSCYAFCCWVLDLNDS
WLSRRMIQRTTGFFRPYQDWNRKPLPTMDDSKLKKVANIFLCTLSSLFTRPIKDIIGK
LKPLNILNILATCDWTFAGIVESLILLAELFGVFWTPPDVSAMIAPLLGDYELQGPED
LVVELVPIVMGGIGLVLGFTKEKIGKMLSSAASTLRACKALGAYGLEILKLVMKRLFP
KKEEANELAMVRSIEDAVLDLEAIENNHMTTLLKDKDSLATYMRTLDLEEEKARKLST
KSASPDIVGTINSLLARIAAARSLVHRAKEELSSCWRAVVVMISGRPGIGKTHLARHL
AKKIAASLTGDQRVGLIPRNGVDHWDAYKGERVVLWDDYGMRHPIQGALRLQELAYTS
PFTLNCDRIENKGKVFDSDAIIITTNLANPAPLDYVNFEACSRRIDFLVYAEAPEVEK
AKRDFPGQPDMWKNAFSPDFSHIKLSLAPQGGFDKNGNTPHGKGVMKTLTTGSLIARA
SGLLHERLDVDTMKGPALTTFNLENSPILAFRQLAAENKYGLMDTMKVGKQLKDVKTM
SDLKQALKNIAIKKCQIVYNGSTYTLEADGRGSVKVDKVQSATVHFVNHLAGALHHLR
CARIRYYVKCVQEALYSMIQIAGAAFVTTRIAMRVNIQNLWSKPQVEDTEEMTSKDGC
LKPKDDEEFVVSSDDIKTEGKKGKNKSDRTPHHWAFSSKGLSDEEYDEYKRIREERNG
KYSIEEYLQDRDRYYEEVVAIARATEEDFCEEEEAKIRQRIFRPTRKQRKEERASLGL
VTGSEIRKRNPEDFKPKGKPWADDDRRVDYNEKLNFEAPPSIWSRIVNFGSGWGFWVS
PSLNTKLTHIIPHGAKEFFGVPIKQIQIHKSGELCRLRFPNPIGTDVAGMILEEGALG
GTVGALPICPPTGAPLNLSVRMGTHATMKIQGRTVGGQMGMLLTGSNAKSMDLGTTPG
DCGCPYIYKRGNDYVVIGVHTAAARGGNTVICATQGSEGEATLEGGDSKGTYCGAPIL
GPGSAPKLSTKTKFWRSSTTPLPPGTYVPAYLGGKDPRVKGGPSLQHVMRDQLKPFTE
PRGKPPRPTVLGDARKTIISVRGQTIVAPRKWSVAQACASLDKTSSCGQPQHMRKNDC
WNGGSVTGKLADQASKANLMFEEGKNMTPVYTGALKDELVKTDKVYAKIKKRLLWGSD
LATMIRCARAFGGLMDELKAHCVTLPVRVGMNMNEDGPIIFEKHSRYRYHYDADYSRW
DSTQQRDVLAAALEIMVKFSPEPHLGQVVADDLLSPSVMDVGDFQISISEGLPSGVPC
TSQWNSIAHWLLTLCALSDVRDRSRDFIQANSLFSFYGDDEIVSTDIKLDPEKLTAKL
KEYGLKPTRPDKTEGPLVISEDLDGLTFLRRTVTRDPAGWFGKLEQSSILRQMYWTRG
PNHADPFETMIPHSPRPIQLMSLLGEAALHGPAFYSQLCKLVIAELKEGGMDFYVPRQ
EPMFRWMRFSDLSTWEGDRNLAPSGVNEDGVE"
mat_peptide 1..990
/gene="ORF1"
/product="p48"
mat_peptide 991..2088
/gene="ORF1"
/product="NTPase"
mat_peptide 2089..2625
/gene="ORF1"
/product="p22"
mat_peptide 2626..3027
/gene="ORF1"
/product="VPg"
mat_peptide 3028..3570
/gene="ORF1"
/product="Pro"
mat_peptide 3571..5100
/gene="ORF1"
/product="RdRp"
gene 5084..6706
/gene="ORF2"
CDS 5084..6706
/gene="ORF2"
/note="major capsid protein"
/codon_start=1
/product="VP1"
/protein_id="QED42446.1"
/translation="MKMASNDAAPSDGSAANLVPEVNNEVMALEPVVGAAIAAPVAGQ
QNVIDPWIRNNFVQAPGGEFTVSPRNAPGEILWSAPLGPDLNPYLSRSARKYNGYAGG
FEVQVILAGNAFTAGKVIFAAVPPNFPTEGLSPSQVTMFPHIVVDVRQLEPVLIPLLD
VRNNFYHYNQSNDPTIKLIAMLYTPLRANNAGDDVFTVSCRVLTRPSPDFDFIFLVPP
TVESRTKPFSVPVLTVEEMTNSRFPIPSEEMSTGHSSGFVVQPQNDRCTTDGVLLGTT
QLSPVSNCTLRGDVPHITSSWSYTMNLVSQNWNNYDPTEEIPAPLGTPDFVGKIQGVL
TQTTRTDGSTRGHKATVYTGSADFSPKLGRVQFETDTDHDFEANQNTKFTPVGVIQDG
STTHRNEPQQCLLPSYSGRNTHNVHPAPAVAPTLPGEQLLFFRTTTPGCIGYPNMDLD
CLLPQEWMQYFYQEAAPAQSDVALLRFVNPDTGRVLFECKLHKSGYVTVAHTGQHDLV
IPPNGYFRFDSWVNQFYTLAPMGNGTGRRRAV"
gene 6706..7512
/gene="ORF3"
CDS 6706..7512
/gene="ORF3"
/note="minor structural protein; small basic protein"
/codon_start=1
/product="VP2"
/protein_id="QED42447.1"
/translation="MAGAFFAGLASDVLGSGLGSLINAGAGAINQKVELKNNRKLQQA
SFQFSSNLQQASFQHDKEMLQAQIEATKKLQQEMMKVKQAMLLEGGFSETCAARGAIN
APMTKALDWSGIRYWAPDARTTTYNAGRFSTPQPSGALPGRANLRDAVPARGSSSKSS
TSSIATSVYSNQTTSTRLGSTAGSGTSVSSLPSTARTRSWVEAQSRNLSPFMRGPHNI
YFVTPPDSRSPSHGTVSTVPKEILDSWTGAFNTRRQPLFAHIRKRGESRA"
ORIGIN
1 ttgaaaatgg cgtctaacga cgcttccgct gccgctgttg ccaacagcaa caacgacatc
61 gcaaaatctt caagtgacgg tgtgttttct aacatggctg tcacttttaa gcggcccctc
121 ggggcgcggc ctaaacagcc gcccccgaag gagataccac ccagaccccc gcgaccaccc
181 acaccagaat tgggcaaaaa gatccctcct cccccaccca acggggagga tgaactagtg
241 gtctcttaca gcgccaaaga tggcgtttcc ggactgcctg agctcaccac tgtcagacaa
301 ccggaagaaa ccaacacggc gttcagtgtc cccccactca accaaaggga gagcagggac
361 gccaaggagc cactaactgg aacaattatt gaaatgtggg atggagaaat ctaccattac
421 ggcctgtacg tggaacgagg tcttatactt ggtgtgcaca agccaccggc agccatcagc
481 cttgccaagg tcgagctaac accgctctct ttgttctgga gacctgtata tactccccag
541 tatctcatct ctccatacac tcttaggagt ttacattgtg actcattccc ctacactgca
601 ttttacaaca gttgctacgc cttttgttgt tgggtattag acctaaacga ctcatggctg
661 agcaggagaa tgattcagag aacaacaggt ttcttcaggc cgtaccagga ttggaacagg
721 aaacccctcc ccactatgga tgattccaaa ttaaagaagg tagccaacat attcttgtgc
781 actctgtctt cactattcac cagacccatt aaggacataa tagggaagtt gaaacctctt
841 aacatcctta acattctggc tacatgtgat tggaccttcg caggcatagt ggaatcttta
901 atactcttag cagaactctt tggagttttc tggacacccc cagatgtgtc tgcgatgatc
961 gccccattgc taggtgatta tgaactgcaa ggacctgagg accttgtagt ggagctggtc
1021 ccaatagtga tgggggggat aggtttggtg ctaggattta ccaaagagaa aattggaaag
1081 atgctatcat ccgctgcatc cactttaaga gcttgtaaag ctcttggtgc atacggattg
1141 gaaatcttaa aattggtcat gaagcggctc ttcccaaaga aagaggaggc aaatgaactg
1201 gctatggtga gatccatcga ggacgcagtg ctagatctcg aggcaattga aaacaaccac
1261 atgaccaccc tactcaaaga caaagacagc ttggcaacct acatgagaac ccttgacctt
1321 gaggaggaga aagctagaaa actctcaacc aaatccgctt cacccgatat tgtgggcaca
1381 atcaactctc ttttggcaag aatcgctgct gcgcgctccc tagtgcatcg ggcgaaagaa
1441 gagctctcca gctgctggag agctgtcgtt gtgatgatat cgggaagacc agggataggg
1501 aaaactcatc ttgccaggca cctggccaag aagatcgcgg cctccctcac aggggaccag
1561 cgtgtgggtc ttatcccacg caatggtgtc gaccactggg acgcatacaa gggcgaaaga
1621 gttgtcctat gggacgacta tggaatgcgc caccccatcc agggtgccct taggttgcag
1681 gagcttgctt acacatcccc cttcacgcta aattgtgaca gaattgagaa caaagggaaa
1741 gtctttgaca gtgatgccat aattatcacc accaatctgg ccaacccagc accactggat
1801 tatgtcaact ttgaagcgtg ctcgagacgt attgacttcc tcgtgtacgc agaggcccct
1861 gaggtggaga aggcgaagcg cgatttccca ggtcaacctg acatgtggaa gaacgctttc
1921 agtcctgact tctcacacat aaaactgtca ttggctccac agggtggttt tgacaagaac
1981 ggcaacaccc cgcatggaaa aggggtcatg aagaccctca ccactggctc cctcatcgcc
2041 cgagcatccg ggttactcca tgagaggcta gatgtggaca caatgaaagg cccggccctc
2101 accactttca acttggaaaa cagcccaata cttgctttta gacagcttgc tgctgaaaac
2161 aagtatgggc tgatggacac aatgaaagtt ggaaaacagc tcaaggatgt caagaccatg
2221 tcagacctca aacaagcact caagaacatc gcgatcaaga agtgccagat agtgtacaat
2281 ggtagcacct acacacttga ggccgatggc aggggtagtg tgaaagttga caaagtgcaa
2341 agtgccactg tgcactttgt gaatcatcta gccggtgccc tacaccacct aaggtgcgct
2401 agaatcagat actatgttaa gtgcgtccag gaggcactgt attccatgat ccaaatcgct
2461 ggggctgcat tcgtcaccac gcgcatagcg atgcgcgtga atatacagaa tctctggtcc
2521 aagccacagg tggaagacac agaagagatg accagcaaag atggttgcct aaaacccaaa
2581 gatgatgaag aatttgtcgt ctcatccgac gacatcaaaa ctgagggcaa gaaagggaag
2641 aacaagtccg atcgtactcc tcatcactgg gccttttcaa gcaaagggct cagtgatgag
2701 gagtacgatg agtacaagag aatcagagaa gaaaggaatg gtaagtactc catagaagag
2761 tacctccagg acagagacag gtactacgag gaggtggtgg ccattgccag ggcaaccgaa
2821 gaggacttct gtgaagaaga agaggccaaa atccggcaga gaatttttag accaacaagg
2881 aaacaacgca aagaagagag ggcctctctc ggcttggtca caggctctga aatcaggaag
2941 agaaatccag aagacttcaa acccaaggga aagccgtggg ctgatgatga cagaagagtt
3001 gactacaatg agaaactcaa ctttgaggcc ccaccaagca tctggtcgcg gatagttaac
3061 tttggttcag gctggggctt ctgggtctcc cccagtctga atacaaaatt aacccatatc
3121 ataccccacg gtgcaaaaga gttcttcgga gtccctatca agcaaatcca gatacacaag
3181 tcaggtgaat tgtgccgctt gagattcccg aacccaatcg gaacggacgt ggcgggcatg
3241 attctagaag aaggtgcgct cgggggaacc gtaggagcac tgcccatttg ccctccaact
3301 ggtgcgcccc tgaatctttc agttagaatg ggaacccatg caaccatgaa aattcagggg
3361 cgcacagttg gagggcaaat gggcatgctc ctgacaggat ccaacgccaa gagtatggac
3421 ctaggcacaa caccaggcga ctgcggctgc ccctacatct acaagagggg gaatgactac
3481 gtggtcatag gagtccatac ggccgctgcc cgtggaggaa acactgtcat atgtgccact
3541 caggggagtg agggagaagc cacacttgaa ggaggtgaca gtaaagggac atactgtggc
3601 gcaccgatct tgggcccagg gagcgctccg aagctcagta ccaagactaa gttttggaga
3661 tcatccacaa caccactccc acctggcacc tacgtaccag cctacctcgg tggcaaagac
3721 cccagagtca aaggtggccc ttcactgcaa cacgttatga gggaccagct gaagccattc
3781 acagaaccca gaggcaaacc accaaggcca actgtgttgg gagatgcaag gaaaaccatc
3841 atcagtgtcc gtgggcaaac aattgttgca ccccgaaaat ggtcagttgc gcaagcttgc
3901 gcatcccttg acaaaacctc ctcctgcgga caaccacaac acatgcggaa aaacgactgt
3961 tggaatgggg ggtccgtcac gggaaaattg gctgatcaag cctccaaggc caacctaatg
4021 tttgaagagg gaaagaacat gactccagtc tacacaggtg cacttaaaga tgagttggta
4081 aagaccgata aagtttatgc taagatcaag aagaggctcc tgtggggttc agatctggcg
4141 accatgatac ggtgcgcccg agcttttgga ggccttatgg atgaactcaa ggcgcactgt
4201 gtcacacttc ctgtcagagt tggcatgaac atgaatgagg atggccccat catctttgag
4261 aagcactcca gatatagata ccactatgat gctgactatt cccggtggga ctcaacacaa
4321 caaagggatg tgctagcagc agccctagaa atcatggtta agttctctcc tgaaccacac
4381 ctgggccagg tagtagcaga cgacctcctt tcccctagcg taatggatgt aggtgacttt
4441 caaatatcaa taagtgaggg tcttccctct ggggtacctt gtacctccca gtggaattcc
4501 atcgcccact ggctcctcac tctttgtgca ctttctgatg tcagggacag gtcccgtgac
4561 ttcattcagg ccaactccct tttctccttc tatggtgatg atgagattgt aagcacagac
4621 ataaagttgg acccagagaa gctgacagca aaactcaagg agtacgggct gaaaccaacc
4681 cgccccgaca aaactgaagg accccttgtt atctctgaag acctggatgg cctgacattc
4741 ctccggagga ctgtgacacg tgatccagct ggctggtttg gaaaattgga acagagttca
4801 attctcaggc aaatgtactg gaccaggggt cccaaccatg cagatccatt tgaaacaatg
4861 ataccacact ccccaagacc catacaattg atgtccttgc tgggcgaggc tgcactccac
4921 ggcccggcat tctacagcca actctgcaaa ttagtcattg cagagttgaa ggaaggtggc
4981 atggattttt acgtgcccag acaagagcca atgttcagat ggatgagatt ctcagatctc
5041 agcacatggg agggcgatcg caatcttgct cccagtggtg tgaatgaaga tggcgtcgaa
5101 tgacgccgct ccatctgatg ggtccgctgc caacctcgtc ccagaggtca acaatgaggt
5161 tatggctctg gagcccgttg ttggtgccgc cattgcggca cctgtagcgg gccaacaaaa
5221 tgtaattgac ccctggatta gaaacaattt tgtacaagcc cctggtggag agttcacagt
5281 atcccctaga aacgctccag gtgaaatact atggagcgcg cccttgggcc ctgacctaaa
5341 tccctaccta tcgcgttcgg ccagaaagta caatggttat gcaggtggtt ttgaagtgca
5401 ggtaattctc gcggggaacg cgttcaccgc cgggaaggtc atatttgcag cagtcccacc
5461 aaattttcca actgaaggct tgagccccag ccaggtcact atgttccccc atatagtagt
5521 agatgttagg caactagaac ctgtgttgat tcccttactc gatgttagga ataatttcta
5581 tcattacaat caatcaaatg atcccactat taagttgata gcaatgttgt atacaccact
5641 tagggctaat aacgctgggg atgatgtctt cacagtttct tgccgagttc tcacgagacc
5701 atcccccgat tttgatttca tatttctagt gccacccaca gttgagtcaa gaactaaacc
5761 attctctgtc ccagttttaa ctgttgagga gatgaccaat tcaagattcc ccattccttc
5821 agaggagatg tcaacgggtc acagcagtgg ctttgttgtc caaccacaaa acgataggtg
5881 cacgactgat ggcgtgctcc taggcaccac ccaactgtct cctgtcagca actgtacctt
5941 acgaggagat gttccccaca tcacaagtag ctggagttac acgatgaatt tggtttctca
6001 gaattggaac aattatgacc caacagaaga aatcccagcc cctctaggaa ctccagactt
6061 tgtggggaag attcaaggtg tactcaccca aaccacaagg acagatggct caacgcgcgg
6121 ccacaaagcc acagtgtaca ctgggagcgc cgatttttct ccaaaactgg gtagagttca
6181 atttgaaact gacacagacc atgattttga agctaaccaa aacacaaagt tcaccccagt
6241 tggtgtcatc caagatggta gcaccaccca ccgaaatgaa ccccaacagt gtttgctccc
6301 aagttactca ggcagaaata ctcataatgt gcatccggcc cccgctgtag ccccgacttt
6361 gccgggtgag caacttctct tcttcaggac caccacgccc ggatgcatcg ggtaccccaa
6421 catggatttg gactgtctcc tcccccagga atggatgcag tacttctacc aagaggcagc
6481 cccagcacaa tctgatgtgg ctctgctaag atttgtgaat ccagacacag gtagggtttt
6541 gtttgagtgt aagcttcata aatcaggcta tgttacagtg gctcacactg gccaacatga
6601 tttggttatt ccccccaatg gttattttag atttgattcc tgggttaacc agttctacac
6661 gcttgccccc atgggaaatg gaacggggcg tagacgtgca gtataatggc tggagctttc
6721 tttgctggat tggcatctga tgtccttggc tctggacttg gttcccttat caatgctggg
6781 gctggggcca tcaaccaaaa agttgagctt aaaaataaca gaaaattgca acaagcatcc
6841 ttccaattta gcagcaatct acaacaggct tcctttcagc atgacaaaga gatgctccaa
6901 gcacaaattg aggccaccaa aaagctacaa caggaaatga tgaaagttaa gcaggcaatg
6961 ctcctagagg gtgggttctc tgagacgtgt gcagcccgcg gggcaatcaa cgcccccatg
7021 acaaaagctt tggactggag cgggataagg tactgggctc ccgatgctag gactacaaca
7081 tacaatgcag gccgcttctc cacccctcaa ccatcggggg cactgccagg aagagctaat
7141 cttagggatg ctgtccctgc tcggggttcc tctagtaaat cttctacctc ttctattgct
7201 acttctgtgt actcaaatca aactacttca acgagacttg gttctacagc tggttctggt
7261 accagtgtct cgagcctccc gtcaactgca aggactagga gctgggtgga ggctcagagt
7321 aggaatttgt cacctttcat gagggggccc cacaacatat attttgtcac cccaccagat
7381 agcagatccc ctagccacgg cacagtctca accgtgccta aagagatttt ggactcctgg
7441 actggcgctt tcaacacgcg caggcagcca ctcttcgctc acattcgtaa gcgaggggag
7501 tcacgggcgt aa
//