Typing tool
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Typing tool
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Complete norovirus genomes
| MN308011 | GII.4 Sydney | |
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| GII.P31 |
ORF1: 1..4994
ORF2: 4975..6597
ORF3: 6597..7403
LOCUS MN308011 7403 bp RNA linear VRL 29-JUN-2021
DEFINITION Norovirus GII isolate 109_GII.Pe_GII.4_Araguaina nonstructural
polyprotein (ORF1) gene, partial cds; and VP1 (ORF2) and VP2 (ORF3)
genes, complete cds.
ACCESSION MN308011
VERSION MN308011.1
KEYWORDS .
SOURCE Norovirus GII
ORGANISM Norovirus GII
Viruses; Riboviria; Orthornavirae; Pisuviricota; Pisoniviricetes;
Picornavirales; Caliciviridae; Norovirus; Norwalk virus.
REFERENCE 1 (bases 1 to 7403)
AUTHORS Tinker,R.J., da Costa,A.C., Tahmasebi,R., Milagres,F.A.P., Dos
Santos Morais,V., Pandey,R.P., Jose-Abrego,A., Brustulin,R.,
Rodrigues Teles,M.D.A., Cunha,M.S., Araujo,E.L.L., Gomez,M.M.,
Deng,X., Delwart,E., Sabino,E.C., Leal,E. and Luchs,A.
TITLE Norovirus strains in patients with acute gastroenteritis in rural
and low-income urban areas in northern Brazil
JOURNAL Arch Virol 166 (3), 905-913 (2021)
PUBMED 33462673
REFERENCE 2 (bases 1 to 7403)
AUTHORS Tinker,R.J., da-Costa,A.C., Leal,E.S., Tahmasebi,R.,
Milagres,F.A.P., Pandey,R.P., Jose-Abrego,A., Brustulin,R.,
Teles,Md.A.R., Sayao-Lobato,M.C.A.B., Chagas,R.T.,
Santos-Abrao,Md.F.N., Alves-Soares,C.V.D., Cunha,M.S., Deng,X.,
Delwart,E., Sabino,E.C. and Luchs,A.
TITLE Direct Submission
JOURNAL Submitted (13-AUG-2019) Institute of Tropical Medicine, University
of Sao Paulo, Av Dr Eneas de Carvalho Aguiar 470, Sao Paulo, Sao
Paulo 05403000, Brazil
COMMENT ##Assembly-Data-START##
Assembly Method :: Geneious v. R9
Sequencing Technology :: Illumina
##Assembly-Data-END##
FEATURES Location/Qualifiers
source 1..7403
/organism="Norovirus GII"
/mol_type="genomic RNA"
/isolate="109_GII.Pe_GII.4_Araguaina"
/isolation_source="feces"
/host="Homo sapiens"
/db_xref="taxon:122929"
/country="Brazil"
/collection_date="22-Sep-2014"
/note="genotype: GII.Pe_GII.4"
gene <1..4994
/gene="ORF1"
CDS <1..4994
/gene="ORF1"
/codon_start=3
/product="nonstructural polyprotein"
/protein_id="QED42421.1"
/translation="RALGARPKQPPPKEIPPRPPRPPTPELVKKIPPPPPNGEEELVV
SYSAKDGVSGLPELTTVRQPEETNTAFSVPPLNQRESRDAKEPLTGTIIEMWDGEIYH
YGLYVERGLILGVHKPPATISLAKVELTPLSLFWRPVYTPQYLISPDTLRRLHGESFP
YTAFDNNCYAFCCWVLDLNDSWLSRRMIQRTTGFFRPYQDWNRKPLPTMDDSKLKKVA
NIFLCTLSSLFTRPIKDIIGKLKPLNILNILATCDWTFAGIVESLILLAELFGVFRTP
PDVSAMIAPLLGDYELQGPEDLVVELVPIVMGGIGLVLGFTKEKIGKMLSSAASTLRA
CKDLGAYGLEILKLVMKWFFPKKEEANELAMVRSIEDAVLDLEAIENNHMTTLLKDKD
SLATYMRTLDLEEEKARKLSTKSASPDIVGTINSLLARIAAARSLVHRAKEELSSRPR
PVVVMISGRPGIGKTHLARELAKKIAASLTGDQRVGLIPRNGVDHWDAYKGERVVLWD
DYGMSNPIHDALRLQELADTCPLTLNCDRIENKGKVFDSDAIIITTNLANPAPLDYVN
FEACSRRIDFLVYAEAPEVEKAKRDFPGQHDMWKNAFSPDFSHIKLSLATQGGFDKNG
NTPHGKGVMKTLTTGSLIARASGLLHERLDEYELQGPALTTFNFDRKKILAFRQLAAE
NKYGLMDTMKVGKQLKDVKTMSDLKQALKNIAIKKCQIVYNGSTYTLEADGRGSVKVD
KVQSATVQTNNELAGALHHLRCARIRYYVKCVQEALYSIIQIAGAAFVTTRIAKRMNI
QNLWSKPQVEDTEEMTSKDGCLKPKDDEEFVVSSDDIKTEGKKGKNKSHRTPHHWAFS
SKGLSDEEYDEYKRIREERNGKYSIEEYLQDRDRYSSMEVAITRATEEDFCEEEEAKI
RQRIFRPTRKQRKEERASFGLVTGSEIRKKNPEDFKPKGKLWADDDRSVDYNEKLNFE
APPSIWSRIVNFGSGWGFWVSPSLIITSTHVIPHGAKEFFGVPIKQIQIHKSGEFCRL
RFPKPIRTDVTGMILEEGAPEGTVATLLIKRPTGELMPLAARMGTHATMKIQGRTVGG
QMGMLLTGSNAKSMDLGTTPGDCGCPYIYKRGNDYVVIGVHTAAARGGNTVICATQGS
EGEATLEGGDSKGTYCGAPILGPGSAPKLSTKTKLRRSSTTPLPPGTYEPAYLGGKDP
RVKGGPSLQQVMTDQLKPFTEPRGKPPEPNFLGAARKTITNVLGKKIVPPQKWSFGQA
CASLDKTSSSGHPHPMRKNDCWNGESFTGKLADQASKANLMFEEGKNMTPVYTGALKD
ELVKTDKVYAKIKKRLLWGSDLATMIRCARAFGGLMDELKAHCVTLPVRVGMNMNEDG
PIIFEKHSRYRYHYDADYSRWDSTQQRDVLAAALEIMVKFSPEPHLAQVVAEDLLSPS
VMDVGDFQISISEGLPSGVPCTSQWNSIAHWLLTLCALSEVTDLSPDIIQANSLFSFY
GDDEIVSTDIKLDPEKLTAKLKEYGLKPTRPDKTEGPLVISEDLDGLTFLRRTVTRDP
AGWFGKLEQSSILRQMYWTRGPNHEDPFETMIPHSLRPIQLMSLLGEAALHGPAFYSK
ISKLVIAELKEGGMDFYVPRQEPMFRWMRFSDLSTWEGDRNLAPSGVNEDGVE"
mat_peptide <1..881
/gene="ORF1"
/product="p48"
mat_peptide 882..1979
/gene="ORF1"
/product="NTPase"
mat_peptide 1980..2516
/gene="ORF1"
/product="p22"
mat_peptide 2517..2918
/gene="ORF1"
/product="VPg"
mat_peptide 2919..3461
/gene="ORF1"
/product="Pro"
mat_peptide 3462..4991
/gene="ORF1"
/product="RdRp"
gene 4975..6597
/gene="ORF2"
CDS 4975..6597
/gene="ORF2"
/note="major capsid protein"
/codon_start=1
/product="VP1"
/protein_id="QED42422.1"
/translation="MKMASNDAAPSDGSAANLVPEVNNEVMALEPVVGAAIAAPVAGQ
QNVIDPWIRNNFVQAPGGEFTVSPRNAPGEILWSAPLGPDLNPYLSHLARMYNGYAGG
FEVQVILAGNAFTAGKIIFAAVPPNFPTEGLSPSQVTMFPHIVVDVKQLEPVLIPLPG
VRNNFYHYNQSNDHTIRLIAMLYTSLRPNNPGDDVFTVSCRVLTRPSPDFDFIFLVPP
TVESRTKPFSVPVLTVERMTNSRFPIPLEKLFTGPSSAFVVQPQNGRCTPDGVLLGTT
QLSPVNICTFRGDVTHITGSRNYTMNLASQNWNNYDPTEEIPAPLGTPDFVGKIQGVL
TQTTRTDGSTRGHKATVYTGSADFAPKLGRVQFETDTDHDFEANQNTKFTPVGVIQDG
STTHRNEPQQWVLPSYSGRNTPNVHLAPAVAPTFPGEQLLFFRSTMPGCSGYPNMDLD
CLLPQEWVQYFYQEAAPAQSDVALLRFVNPDTGRVLFECKLHKSGYVTVAHTGQHDLV
IPPNGYFRFDSWVNQFYTLAPMGNGTGRRRAV"
gene 6597..7403
/gene="ORF3"
CDS 6597..7403
/gene="ORF3"
/note="minor structural protein; small basic protein"
/codon_start=1
/product="VP2"
/protein_id="QED42423.1"
/translation="MAGAFFAGLASDVLGSGLGSLINAGAGAINQKVEFENNRKLQQA
SFQFSSNLQQASFQHDKEMLQAQIEATKKLQQEMMKVKQAMLLEGGFSETDAARGAIN
APMTKALDWSGTRYWAPDARTTTYNAGRFSTPEPSGALPGRANLRDAVPARGSSSKSS
NSSIATSVYSNQTTSTRLGSTAGSGTSVSSLPSTARTRSWVEDQSRNLSPFMRGAHNI
SFVTPPSSRSSSQGTVSTVPKEVLDSWTGAFNTRRQPLFAHIRKRGESRA"
ORIGIN
1 agcgggccct cggggcgcgg cctaaacagc cgcccccgaa ggaaatacca cccagacccc
61 cgcgaccacc cacaccagaa ttggtcaaaa agatccctcc tcccccaccc aacggggagg
121 aggaactagt ggtctcttac agcgccaaag atggcgtttc cggactgcct gagctcacca
181 ctgtcagaca accggaagaa accaacacgg cgttcagtgt ccccccactc aaccaaaggg
241 agagcaggga cgccaaggag ccactaactg gaacaattat tgaaatgtgg gatggagaaa
301 tctaccatta cggcctgtac gtggaacgag gtcttatact tggtgtgcac aagccaccgg
361 caaccatcag ccttgccaag gtcgagctaa caccgctctc tttgttctgg agacctgtat
421 acacccccca gtatctcatc tctccagaca ctcttaggag attacatgga gagtcattcc
481 cctacactgc atttgacaac aattgctacg ccttttgttg ttgggtatta gacctaaacg
541 actcatggct aagcaggaga atgattcaga gaacaacagg tttcttcagg ccgtaccagg
601 attggaacag gaaacccctc cccactatgg atgattccaa attaaagaag gtagccaaca
661 tattcttgtg cactttgtct tcactattca ccagacccat taaggacata atagggaagt
721 tgaaacctct taacatcctt aacattctgg ctacatgtga ttggaccttc gcaggcatag
781 tggaatcttt aatactctta gcagaactct ttggagtttt ccggacaccc ccagatgtgt
841 ctgcgatgat cgcccccttg ctaggtgatt atgaactgca aggacctgag gaccttgtag
901 tggagctggt cccaatagtg atggggggga taggtttggt gctaggattt accaaagaga
961 aaattggaaa gatgctatca tccgctgcat ccactttaag agcttgtaaa gaccttggtg
1021 catacggatt ggaaatctta aaattggtca tgaagtggtt cttcccaaag aaagaggagg
1081 caaatgaact ggctatggtg agatccatcg aggacgcagt gctagacctc gaggcaattg
1141 aaaacaacca catgaccacc ctactcaaag acaaagacag cttggcaacc tacatgagaa
1201 cccttgacct tgaggaggaa aaagccagaa aactctcaac caaatctgcc tcacccgata
1261 ttgtgggcac aatcaactct cttctggcaa gaatcgctgc tgcacgctcc ctagtgcatc
1321 gggcgaaaga agagctctcc agcaggccga gacctgtcgt tgtgatgata tcgggaagac
1381 cagggatagg gaaaactcat cttgccaggg agctggccaa gaagatcgcg gcctccctca
1441 caggggacca gcgtgtgggt cttatcccac gcaatggtgt cgaccactgg gacgcataca
1501 agggcgaaag agttgtccta tgggacgact atggaatgag caaccccatc catgatgccc
1561 tcaggttgca ggagcttgct gacacttgcc ccctcacgct aaattgtgac agaattgaga
1621 acaaagggaa agtctttgac agtgatgcca taattatcac caccaatctg gccaacccag
1681 caccactgga ttatgtcaac tttgaagcgt gctcgagacg tattgacttc ctcgtgtacg
1741 cagaggcccc tgaggtggag aaggcgaagc gcgatttccc aggtcaacat gacatgtgga
1801 agaacgcttt cagtcctgac ttctcacaca taaaactgtc gttggctaca cagggtggtt
1861 ttgacaagaa cggcaacacc ccgcatggaa aaggggtcat gaaaaccctc accactggct
1921 ccctcatcgc ccgagcatca gggttactcc atgagaggct agatgaatat gaactgcaag
1981 gcccagccct caccactttc aactttgacc gcaagaagat acttgctttt agacagcttg
2041 ctgctgaaaa caagtatggg ctgatggaca caatgaaagt tggaaaacag ctcaaggatg
2101 tcaagaccat gtcagacctc aaacaagcac tcaagaacat cgcgatcaag aagtgccaga
2161 tagtgtacaa tggtagcacc tacacacttg aggccgatgg caggggtagt gtgaaagttg
2221 acaaagtgca gagtgccact gtgcagacca acaatgaact agccggtgcc ctacaccacc
2281 taaggtgcgc tagaatcaga tactatgtta agtgcgtcca ggaggcactg tattccatca
2341 tccaaatcgc tggggctgca ttcgtcacca cgcgcatcgc taagcgcatg aatatacaga
2401 atctctggtc caagccacag gtggaagaca cagaagagat gaccagcaaa gatggttgcc
2461 taaaacccaa agatgatgaa gaatttgtcg tctcatccga cgacatcaaa actgagggca
2521 agaaagggaa gaacaagtcc catcgtactc ctcatcactg ggccttttca agcaaagggc
2581 tcagtgatga ggagtacgat gagtacaaga gaatcagaga agaaaggaat ggtaagtact
2641 ccatagaaga gtaccttcag gacagagaca ggtactcttc tatggaggtg gccattacca
2701 gggcaaccga agaggacttc tgtgaagaag aagaggccaa aatccggcag agaattttca
2761 gaccaacaag gaaacaacgc aaagaagaga gggcctcttt cggcttggtc acaggctctg
2821 aaatcaggaa gaaaaaccca gaagacttca aacccaaggg aaagctgtgg gctgatgatg
2881 acagaagtgt tgactacaat gagaaactca actttgaggc cccaccaagc atctggtcgc
2941 ggatagttaa ctttggttca ggctggggct tctgggtctc ccccagtctg attataacat
3001 caacccatgt cataccccac ggtgcaaaag agttcttcgg agtccctatc aagcaaatcc
3061 agatacacaa atcaggtgaa ttctgccggt tgagattccc aaagccaatc agaactgatg
3121 tgacgggcat gattctagaa gaaggtgcgc ccgagggaac cgtggccaca ctgctcatca
3181 agaggccaac tggagagctc atgcctctgg cagccagaat gggaacccat gcaaccatga
3241 aaattcaggg gcgcacagtt ggagggcaaa tgggcatgct cctgacagga tccaacgcca
3301 agagtatgga cctaggcaca acaccaggcg actgcggctg cccctacatc tacaagaggg
3361 ggaatgacta cgtggtcata ggagtccata cggccgctgc ccgtggagga aacactgtca
3421 tatgtgccac tcaggggagt gagggagaag ccacacttga aggaggtgac agtaaaggga
3481 catactgtgg cgcaccaatc ttgggcccag ggagcgctcc gaagctcagt accaagacta
3541 agcttcggag atcatccaca acaccactcc cacctggcac ctacgaacca gcctacctcg
3601 gtggcaaaga ccccagagtc aaaggtggcc cttcattgca acaagttatg acagaccagc
3661 taaagccatt cacagaaccc agaggaaaac cgccagagcc aaatttttta ggggctgcaa
3721 ggaaaaccat caccaatgtc cttgggaaga aaattgttcc accccaaaaa tggtcatttg
3781 gccaagcttg cgcatccctg gacaaaacct cctccagcgg ccacccccac cccatgcgga
3841 aaaacgattg ttggaatggg gagtccttca cgggaaaatt ggctgatcaa gcctccaagg
3901 ccaacctaat gtttgaagag ggaaagaaca tgactccagt ctacacaggt gcacttaaag
3961 atgagttggt aaagaccgat aaagtttatg ctaagatcaa gaagaggctc ctgtggggtt
4021 cagatctggc gaccatgata cggtgcgccc gagcttttgg aggccttatg gatgaactca
4081 aggcgcactg tgtcacactt cctgtcagag ttggcatgaa catgaatgag gatggcccca
4141 tcatctttga gaagcactcc agatatagat atcactatga tgctgactat tcccggtggg
4201 actcaacaca acaaagggat gtgctagcag cagcactaga aatcatggtt aagttctctc
4261 cagaaccaca cctggcccag gtagttgcag aagacctcct ttcccctagc gtaatggatg
4321 taggtgactt tcaaatatca ataagtgagg gtcttccctc tggggtacct tgtacctccc
4381 agtggaattc catcgcccac tggctcctca ctctgtgtgc actctctgaa gtcacggacc
4441 tgtcccctga tatcattcag gccaactccc ttttctcctt ctatggtgat gatgagattg
4501 taagcacaga cataaagttg gacccagaga agctgacagc aaaactcaag gagtacgggc
4561 tgaaaccaac ccgccccgac aaaactgaag gaccccttgt tatctctgaa gacctggatg
4621 gcctgacatt ccttcggaga actgtgaccc gtgatccagc tggctggttt ggaaaattgg
4681 aacaaagttc aattctcaga caaatgtact ggaccagggg tcccaatcat gaggatccat
4741 ttgaaacaat gataccacac tccttaagac ccatacaatt gatgtccttg ctgggcgagg
4801 ctgcactcca cggcccggca ttttatagca aaattagcaa attagtcatt gcagagttga
4861 aggaaggtgg catggatttt tacgtgccca gacaagagcc aatgttcaga tggatgagat
4921 tctcagatct cagcacatgg gagggcgatc gcaatcttgc tcccagtggt gtgaatgaag
4981 atggcgtcga atgacgccgc tccatctgat gggtccgcag ccaacctcgt cccagaggtc
5041 aacaatgagg ttatggctct ggagcccgtt gttggtgccg ccattgcggc acctgtagcg
5101 ggccaacaaa atgtaattga cccctggatt agaaacaatt ttgtacaagc ccctggtgga
5161 gagttcacag tatcccctag aaacgctcca ggtgaaatac tatggagcgc gcccttgggc
5221 cctgacctaa atccctacct atcccatttg gccagaatgt acaatggtta tgcaggtggt
5281 tttgaagtgc aggtaattct cgcggggaac gcgttcaccg ccgggaagat catatttgca
5341 gcagtcccac caaattttcc aactgaaggc ttgagcccca gccaggtcac tatgttcccc
5401 catatagtag tagatgttaa gcaactagaa cctgtgttga ttcccttacc cggtgttagg
5461 aataatttct atcattataa tcaatcaaat gatcacacta ttaggttgat agcaatgttg
5521 tatacatcac ttaggcctaa taatccgggg gatgatgtct tcacagtttc ctgccgagtt
5581 ctcacgagac catcccccga ttttgatttc atatttctag tcccacccac agttgagtca
5641 agaactaaac cattctctgt cccagtttta actgttgaga gaatgaccaa ttcaagattc
5701 cccattcctt tggaaaagtt gttcacgggt cccagcagtg cctttgttgt ccaaccacaa
5761 aacggcaggt gcacgcctga tggcgtgctc ctaggcacca cccaactgtc tcctgtcaac
5821 atctgtacct tcagaggaga tgtcacccat atcacaggta gtcgtaacta cacaatgaat
5881 ttggcttctc aaaattggaa caattatgac ccaacagaag aaatcccagc ccctctagga
5941 actccagact ttgtggggaa gattcaaggt gtactcaccc aaaccacaag gacagatggc
6001 tcaacacgcg gtcacaaagc cacagtgtac actgggagcg ccgactttgc tccaaaactg
6061 ggtagagtac aatttgaaac tgacacagac catgattttg aagctaacca aaacacaaag
6121 ttcaccccag ttggtgtcat ccaagatggt agcaccaccc accgaaatga accccaacag
6181 tgggtgctcc caagctactc aggcagaaat actcccaatg tgcatctggc ccccgctgta
6241 gcccccactt ttccgggtga gcaacttctc ttctttagat ccaccatgcc cggatgcagc
6301 gggtacccca acatggattt ggactgtctg ctcccccagg aatgggtgca gtacttctac
6361 caagaggcag ccccagcaca atctgatgtg gctctgctaa gatttgtgaa tccagacaca
6421 ggtagggttt tgtttgagtg taagcttcat aaatcaggct atgttacagt ggctcacact
6481 ggccaacatg atttggttat tccccccaat ggttatttta gatttgattc ctgggttaac
6541 cagttctaca cgcttgcccc catgggaaat ggaacggggc gtagacgtgc agtataatgg
6601 ctggagcttt ctttgctgga ttggcatctg atgtccttgg ctccggactt ggttccctta
6661 tcaatgctgg ggctggggcc atcaaccaaa aagttgagtt tgaaaataac agaaaattgc
6721 aacaagcatc cttccaattt agcagcaatc tacaacaggc ttcctttcag catgacaaag
6781 agatgctcca agcacaaatt gaggccacca aaaagctaca acaggaaatg atgaaagtta
6841 agcaggcaat gctcctagag ggtgggttct ctgagacaga tgcagcccgc ggggcgatca
6901 acgcccccat gacaaaagct ttggactgga gcgggacaag gtactgggct cccgatgcta
6961 ggactacaac atacaatgca ggccgcttct ccacccccga accatcgggg gcactgccag
7021 gaagagctaa tcttagggat gctgtccctg ctcggggttc ctccagtaaa tcttctaact
7081 cttcaattgc tacttctgtg tactcaaatc aaactacttc aacgagactt ggttctacag
7141 ctggttctgg taccagtgtc tcgagcctcc cgtcaactgc aaggactagg agctgggttg
7201 aggatcagag taggaatttg tcacctttca tgaggggggc ccacaacata tcgtttgtca
7261 ccccaccatc tagcagatcc tctagccaag gcacagtctc aaccgtgcct aaagaggttt
7321 tggactcctg gactggcgct ttcaacacgc gcaggcagcc actcttcgct cacattcgta
7381 agcgagggga gtcacgggcg taa
//