Typing tool
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Typing tool
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Complete norovirus genomes
| MN308000 | GII.4 Sydney | |
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| GII.P31 |
ORF1: 1..5097
ORF2: 5078..6700
ORF3: 6700..7506
LOCUS MN308000 7506 bp RNA linear VRL 29-JUN-2021
DEFINITION Norovirus GII isolate 049_GII.Pe_GII.4_Couto Magalhaes
nonstructural polyprotein (ORF1) gene, partial cds; and VP1 (ORF2)
and VP2 (ORF3) genes, complete cds.
ACCESSION MN308000
VERSION MN308000.1
KEYWORDS .
SOURCE Norovirus GII
ORGANISM Norovirus GII
Viruses; Riboviria; Orthornavirae; Pisuviricota; Pisoniviricetes;
Picornavirales; Caliciviridae; Norovirus; Norwalk virus.
REFERENCE 1 (bases 1 to 7506)
AUTHORS Tinker,R.J., da Costa,A.C., Tahmasebi,R., Milagres,F.A.P., Dos
Santos Morais,V., Pandey,R.P., Jose-Abrego,A., Brustulin,R.,
Rodrigues Teles,M.D.A., Cunha,M.S., Araujo,E.L.L., Gomez,M.M.,
Deng,X., Delwart,E., Sabino,E.C., Leal,E. and Luchs,A.
TITLE Norovirus strains in patients with acute gastroenteritis in rural
and low-income urban areas in northern Brazil
JOURNAL Arch Virol 166 (3), 905-913 (2021)
PUBMED 33462673
REFERENCE 2 (bases 1 to 7506)
AUTHORS Tinker,R.J., da-Costa,A.C., Leal,E.S., Tahmasebi,R.,
Milagres,F.A.P., Pandey,R.P., Jose-Abrego,A., Brustulin,R.,
Teles,Md.A.R., Sayao-Lobato,M.C.A.B., Chagas,R.T.,
Santos-Abrao,Md.F.N., Alves-Soares,C.V.D., Cunha,M.S., Deng,X.,
Delwart,E., Sabino,E.C. and Luchs,A.
TITLE Direct Submission
JOURNAL Submitted (13-AUG-2019) Institute of Tropical Medicine, University
of Sao Paulo, Av Dr Eneas de Carvalho Aguiar 470, Sao Paulo, Sao
Paulo 05403000, Brazil
COMMENT ##Assembly-Data-START##
Assembly Method :: Geneious v. R9
Sequencing Technology :: Illumina
##Assembly-Data-END##
FEATURES Location/Qualifiers
source 1..7506
/organism="Norovirus GII"
/mol_type="genomic RNA"
/isolate="049_GII.Pe_GII.4_Couto Magalhaes"
/isolation_source="feces"
/host="Homo sapiens"
/db_xref="taxon:122929"
/country="Brazil"
/collection_date="21-Sep-2015"
/note="genotype: GII.Pe_GII.4"
gene <1..5097
/gene="ORF1"
CDS <1..5097
/gene="ORF1"
/codon_start=1
/product="nonstructural polyprotein"
/protein_id="QED42388.1"
/translation="MASNDASAAAVANSNNDIAKSSSDGVFSNMAVTFKRALGARPKQ
PPPKEVPPRPPRPPTPELVKKIPPPPPNGEDELVVSYSAKDGVSGLPELTTVRQPEET
NTAFSVPPLNQRESRDAKEPLTGTIIEMWDGEIYHYGLYVERGLILGVHKPPAAISLA
KVELAPLSLFWRPVYTPQYLISPDTLRRLHGESFPYTAFDNNCYAFCCWVLDLNDSWL
SRRMIQRTTGFFRPYQDWNRKPLPTMDDSKLKKVANIFLCTLSSLFTRPIKDIIGKLK
PLNILNILATCDWTFAGIVESLILLAELFGVFWTPPDVSAMIAPLLGDYELQGPEDLA
VELVPIVMGGIGLVLGFTKEKIGKMLSSAASTLRACKDLGAYGLEILKLVMKWFFPKK
EEANELAMVRSIEDAVLDLEAIENNHMTTLLKDKDSLATYMRTLDLEEEKARKLSTKS
ASPDIVGTINSLLARIAAARSLVHRAKEELSSRPRPVVVMISGRPGIGKTHLARELAK
KIAASLTGDQRVGLIPRNGVDHWDAYKGERVVLWDDYGMSNPIHDALRLQELADTCPL
TLNCDRIENKGKVFDSDAIIITTNLANPAPLDYVNFEACSRRIDFLVYAEAPEVEKAK
RDFPGQPDMWKNAFSPDFSHIKLSLAPQGGFDKNGNTPHGKGVMKTLTTGSLIARASG
LLHERLDEYELQGPALTTFNFDRNKILAFRQLAAENKYGLMDTMRVGKQLKDVKTMSD
LKQALKNIAIKKCQIVYNGGTYTLEADGKGSVKVDKVQSATVQTNNELAGALHHLRCA
RIRYYVKCVQEALYSIIQIAGAAFVTTRIAKRMNIQNLWSKPQVEDTEEMANKDGCLQ
PKDDEEFVVSSDDIKTEGRKGKNKSGRGKKHTAFSSKGLSDEEYDEYKRIREERNGKY
SIEEYLQDRDRYSSMEVAITMATEEDFCEEEEAKIRQRIFRPTRKQRKEERASLGLVT
GSEIRKRNPEDFKPKGKLWADDDRSVDYNEKLNFEAPPSIWSRIVNFGSGWGFWVSPS
LFITSTHVIPQGAKEFFGVPIKQIQIHKSGEFCRLRFPKPIRTDVTGMILEEGAPEGT
VATLLIKRPTGELMPLAARMGTHATMKIQGRTVGGQMGMLLTGSNAKSMDLGTTPGDC
GCPYIYKRGNDYVAIGVHTAAARGGNTVICATQGSEGEATLEGGDSKGTYCGAPILGP
GSAPKLSTKTKFWRSSTTPLPPGTYEPAYLGGKDPRVKGGPSLQQVMRDQLKPFTEPR
GKPPRPNVLEAAKKTIINVLEQTIDPPQKWSFAQACASLDKTTSSGHPHHMRKNDCWN
GESFTGKLADQASKANLMFEEGKNMTPVYTGALKDELVKTDKVYGKVKKRLLWGSDLA
TMIRCARAFGGLMDELKAHCVTLPVRVGMNMNEDGPIIFEKHSRYRYHYDADYSRWDS
TQQRDVLAAALEIMVKFSPEPHLAQIVAEDLLSPSVMDVGDFQISISEGLPSGVPCTS
QWNSIAHWLLTLCALSEVTDLSPDIIQANSLFSFYGDDEIVSTDIKLDPEKLTAKLKE
YGLKPTRPDKTEGPLVISEDLDGLTFLRRTVTRDPAGWFGKLEQSSILRQMYWTRGPN
HEDPFETMIPHSQRPIQLMSLLGEAALHGPAFYSKISKLVIAELKEGGMDFYVPRQEP
MFRWMRFSDLSTWEGDRNLAPSFVNEDGVE"
mat_peptide <1..984
/gene="ORF1"
/product="p48"
mat_peptide 985..2082
/gene="ORF1"
/product="NTPase"
mat_peptide 2083..2619
/gene="ORF1"
/product="p22"
mat_peptide 2620..3021
/gene="ORF1"
/product="VPg"
mat_peptide 3022..3564
/gene="ORF1"
/product="Pro"
mat_peptide 3565..5094
/gene="ORF1"
/product="RdRp"
gene 5078..6700
/gene="ORF2"
CDS 5078..6700
/gene="ORF2"
/note="major capsid protein"
/codon_start=1
/product="VP1"
/protein_id="QED42389.1"
/translation="MKMASSDANPSDGSAANLVPEVNNEVLALEPVVGAAIAAPVAGQ
QNVIDPWIRNNFVQAPGGEFTVSPRNAPGEILWSAPLGPDLNPYLSHLARMYNGYAGG
FEVQVILAGNAFTAGKVIFAAVPPNFPTEGLSPSQVTMFPHIVVDVRQLEPVLIPLPD
VRNNFYHYNQSNDPTIKLIAMLYTPLRANNAGDDVFTVSCRVLTRPSPDFDFIFLVPP
TVESRTKPFSVPVLTVEEMTNSRFPIPLEKLFTGPSSAFVVQPQNGRCTTDGVLLGTT
QLSPVNICTFRGDVTHITGSRNYTMNLASQNWSNYDPTEEIPAPLGTPDFVGKIQGML
TQTTRTDGSTRGHKATVYTGSAGFSPKLGRVQFETDTDHDFEANQNTKFTPVGVIQDG
STTHRNEPQQWVLPSYSGRNTPNVHLAPAVAPTFPGEQLLFFRSTMPGCSGYPNMDLD
CLLPQEWVQYFYQEAAPAQSDVALLRFVNPDTGRVLFECKLHKSGYVTVAHTGQHDLV
IPPNGYFRFDSWVNQFYTLAPMGNGTGRRRAL"
gene 6700..7506
/gene="ORF3"
CDS 6700..7506
/gene="ORF3"
/note="minor structural protein; small basic protein"
/codon_start=1
/product="VP2"
/protein_id="QED42390.1"
/translation="MAGAFFAGLASDVLGSGLGSLINAGAGAINQKVEFENNRKLQQA
SFQFSSNLQQASFQHDKEMLQAQIEATKRLQQEMMKVKQAVLLEGGFSETDAARGAIN
APMTKALDWSGTRYWAPDARTTTYNAGRFSTPQPSGALPGRANLRDAVPARGSSSKSS
NSLTATSVYSNQTTSTRLGSTAGSGTSVSSFPSTARTRSWVEDQSRNLSPFMRGAHNI
SFVTPPSSRSSSQGTVSTVPKEILDSWTGAFNTRRQPLFAHIRKRGESRA"
ORIGIN
1 atggcgtcta acgacgcttc cgctgccgct gttgccaaca gcaacaacga catcgcaaaa
61 tcttcaagtg acggtgtgtt ttctaacatg gctgtcactt ttaagcgggc cctcggggcg
121 cggcctaaac agccgccccc gaaggaagta ccacccagac ccccgcgacc acccacacca
181 gaattggtca aaaagatccc tcctccccca cccaacgggg aggatgaact agtggtctct
241 tacagcgcca aagatggcgt ttccggattg cctgagctca ccactgtcag acaaccggaa
301 gaaaccaaca cggcgttcag tgtcccccca ctcaaccaaa gggagagcag ggacgccaag
361 gagccactaa ctggaacaat cattgaaatg tgggatggag aaatctacca ttacggcctg
421 tacgtggaac gaggtcttat acttggtgtg cacaagccac cggcagccat tagccttgcc
481 aaggtcgagc tagcaccgct ctctttgttc tggagacctg tatacacccc ccagtatctc
541 atctctccgg acactcttag gagattgcat ggagagtcat tcccttacac tgcatttgac
601 aacaattgct acgcattttg ttgttgggta ttagacctaa acgactcatg gctaagcagg
661 agaatgattc agagaacaac aggcttcttt aggccgtacc aggattggaa caggaaaccc
721 ctccccacta tggatgattc caagttaaag aaggtagcca acatattctt gtgcactttg
781 tcttcactat tcaccagacc cattaaggat ataataggga agttgaaacc tcttaacatc
841 cttaacattc tggctacatg tgattggacc ttcgcaggca tagtggaatc cttaatactc
901 ttggcagaac tctttggagt tttctggaca cccccagatg tgtctgcgat gatcgccccc
961 ttgctaggtg attatgaact gcaaggacct gaggaccttg cagtggaact ggtcccaata
1021 gtgatggggg ggataggttt ggtgctagga tttaccaaag agaaaatcgg aaagatgcta
1081 tcatccgctg catccacttt aagagcttgc aaagaccttg gtgcatacgg actggaaatc
1141 ttaaaattgg tcatgaagtg gttcttccca aagaaagagg aagcaaatga actggctatg
1201 gtgagatcca tcgaggatgc agtactagac cttgaggcaa ttgaaaacaa ccacatgacc
1261 accctactca aagacaaaga cagcttggca acctacatga gaacccttga ccttgaggag
1321 gagaaagcca gaaaactctc aaccaaatct gcttcacccg atattgtggg cacaatcaac
1381 tctcttctgg caagaatcgc tgctgcacgc tccctagtgc atcgggcgaa agaagagctt
1441 tccagcaggc cgagacctgt cgttgtgatg atatcgggaa gaccagggat agggaaaact
1501 caccttgcca gggagctggc caagaagatt gcggcctccc tcacagggga ccagcgtgtg
1561 ggtcttatcc cacgcaatgg tgtcgaccac tgggacgcat acaagggcga aagagttgtc
1621 ctatgggacg actatggaat gagcaacccc atccatgatg ccctcaggtt acaggagctt
1681 gctgacactt gccccctcac gctaaattgt gacagaattg agaacaaagg gaaagtcttt
1741 gacagtgatg ccataattat taccaccaat ctggccaacc cagcaccact ggattatgtt
1801 aactttgaag cgtgctcgag acgcattgat ttcctcgtgt acgctgaagc ccctgaggtg
1861 gagaaggcaa agcgcgactt cccaggtcaa cctgacatgt ggaagaacgc tttcagtcct
1921 gacttctcac acataaaact gtcattggct ccacagggtg gttttgacaa gaatggcaac
1981 accccgcatg gaaaaggggt catgaagacc ctcactactg gctccctcat cgcccgagca
2041 tcagggttac tccatgagag gctagatgaa tatgaactgc aaggcccggc cctcaccact
2101 ttcaactttg accgcaacaa gatacttgct tttagacagc ttgctgctga aaacaagtat
2161 gggctgatgg acacaatgag agttggaaaa caactcaagg atgtcaagac catgtcagac
2221 ctcaaacaag cactcaagaa catcgcgatc aaaaagtgcc agatagtgta caatggtggc
2281 acctacacac ttgaggctga tggcaagggt agtgtgaaag ttgacaaagt gcaaagtgcc
2341 actgtgcaga ccaacaatga acttgccggt gccctacacc acctaaggtg cgctagaatc
2401 agatactatg ttaagtgcgt ccaggaggca ctgtattcca tcatccaaat cgctggggct
2461 gcattcgtca ccacgcgcat cgctaagcgc atgaatatac agaatctctg gtctaagcca
2521 caggtggaag acacagaaga gatggctaac aaagatggtt gcctacaacc caaagatgat
2581 gaagagtttg tcgtctcatc cgacgacatc aaaactgagg gcagaaaggg aaagaacaag
2641 tccggccgtg gcaagaagca cacagctttt tcaagtaaag gactcagtga tgaggagtac
2701 gatgagtaca agaggatcag agaagaaagg aatggtaagt actccataga agagtacctt
2761 caggacagag acaggtactc ctctatggag gtggccatta ccatggcaac cgaagaggac
2821 ttctgtgaag aagaagaggc caaaatccgg cagagaattt tcaggccaac aaggaaacaa
2881 cgcaaagaag agagggcctc tctcggcttg gtcacaggct ctgaaatcag gaagagaaac
2941 ccagaagact tcaaacccaa gggaaagctg tgggctgatg atgacagaag tgttgactac
3001 aatgagaaac tcaactttga ggccccacca agcatctggt cgcggatagt caactttggt
3061 tcaggctggg gcttctgggt ctcccccagt ctgtttataa catcaaccca tgtcataccc
3121 caaggtgcaa aagagttctt cggagtccct atcaagcaaa tccagataca caagtcaggt
3181 gaattctgcc ggttgagatt cccaaagcca atcagaactg atgtgacggg catgattcta
3241 gaagaaggtg cgcccgaggg gaccgtggcc acactgctca tcaagagacc aactggagag
3301 ctcatgcctc tggcagccag aatggggacc catgcaacca tgaaaattca ggggcgcaca
3361 gttggaggac aaatgggtat gctcctgaca ggatccaatg ccaagagtat ggacctaggc
3421 acaacaccag gcgactgcgg ctgcccctac atctacaaga gggggaatga ctacgtggcc
3481 ataggagtcc atacggccgc tgcccgtgga ggaaacactg tcatatgtgc cacccagggg
3541 agtgagggag aagccacact tgaaggaggt gacagtaaag ggacatactg tggcgcacca
3601 atcttgggcc cagggagcgc tccgaagctc agtaccaaga ctaagttttg gagatcatcc
3661 acaacaccac tcccacctgg cacctacgaa ccagcctacc tcggtggcaa agaccctaga
3721 gtcaaaggtg gtccttcatt gcagcaagtt atgagggacc agctgaagcc attcacagaa
3781 cccagaggca aaccgccaag accaaatgta ttggaagctg ccaagaaaac catcatcaat
3841 gtccttgagc aaacaattga tccacctcaa aaatggtcat ttgcgcaagc ttgcgcatcc
3901 cttgacaaaa ctacctccag cggccacccc caccacatgc ggaaaaacga ctgttggaat
3961 ggggagtcct tcacgggaaa gttggctgat caagcctcca aggccaatct aatgtttgaa
4021 gagggaaaga acatgactcc agtttacaca ggtgcactta aagatgagtt ggtaaagacc
4081 gataaagttt atggtaaggt caagaagagg cttctgtggg gttcagatct ggcgaccatg
4141 atacggtgcg cccgagcttt tggaggcctt atggatgaac tcaaggcaca ctgtgtcaca
4201 cttcctgtca gagttggtat gaacatgaat gaggatggcc ccatcatctt tgagaagcac
4261 tccagatata gatatcacta tgatgctgat tattcccggt gggattcaac acaacaaagg
4321 gatgtgctag cagcagcact agaaatcatg gttaagttct ctccagagcc gcacctggcc
4381 cagatagttg cagaagacct cctctcccct agcgtgatgg atgtaggtga ctttcaaata
4441 tcaataagtg aaggtctccc ctctggggta ccttgtacct cccagtggaa ttccatcgcc
4501 cactggctcc tcactctgtg tgcactctct gaagtcacgg acctgtcccc tgatatcatt
4561 caggccaact cccttttctc cttctatggt gatgatgaaa ttgtaagcac agacataaag
4621 ttggacccag agaagctgac agcaaaactc aaggagtacg ggctgaaacc aacccgcccc
4681 gacaaaactg aaggacccct tgttatctct gaagacctgg atggcctgac attcctccgg
4741 agaactgtga cccgtgatcc agctggctgg tttggaaaat tggaacaaag ttcaattctc
4801 aggcaaatgt actggaccag gggtcccaac catgaagatc catttgaaac aatgatacca
4861 cactcccaaa gacccataca attgatgtcc ttgctgggcg aggctgcact ccacggcccg
4921 gcattctata gcaaaattag caaattagtc attgcagagt tgaaggaagg tggcatggat
4981 ttttacgtac ccagacaaga gccaatgttc agatggatga gattctcaga tctgagtacg
5041 tgggagggcg atcgcaatct ggctcccagt tttgtgaatg aagatggcgt cgagtgacgc
5101 caacccatct gatgggtccg cagccaacct cgtcccagag gtcaacaatg aggttttggc
5161 tctggagccc gttgtaggtg ccgccattgc ggcacctgta gcgggccaac aaaatgtaat
5221 tgacccctgg attagaaata attttgtaca agcccctggt ggagagttta cagtatcccc
5281 tagaaacgct ccaggtgaaa tactatggag cgcgcccttg ggccctgatc tgaatcccta
5341 cctatcccat ttggccagaa tgtacaatgg ttatgcaggt ggttttgaag tgcaggtaat
5401 tctcgcgggg aacgcgttca ccgccgggaa ggtcatattt gcagcagtcc caccaaattt
5461 tccaactgaa ggcttgagcc ccagccaggt cactatgttc ccccatatag tagtagatgt
5521 taggcaacta gaacctgtgt tgattccctt acccgatgtt aggaataatt tctatcatta
5581 caatcaatca aatgacccca ctattaagtt gatagcaatg ttgtacacac cacttagggc
5641 taataatgct ggggatgacg tcttcacagt ttcttgccga gttctcacga gaccatcccc
5701 cgattttgat ttcatatttc tagtgccacc cacagttgag tcaagaacta aaccattctc
5761 tgtcccagtt ttaactgttg aggagatgac caattcaaga ttccccattc ctttggaaaa
5821 gttgttcacg ggtcccagca gtgcctttgt tgtccaacca caaaacggta ggtgtacgac
5881 tgatggcgtg ctcctaggca ccacccaact gtcccctgtc aacatttgca ccttcagagg
5941 agatgtcacc catatcacag gtagtcgcaa ctacacaatg aatttggctt ctcagaattg
6001 gagcaattat gacccaacag aagaaatccc agcccctcta ggaactccag attttgtggg
6061 gaagattcaa ggcatgctca cccaaaccac aaggacagat ggctcgacac gcggccacaa
6121 agccacagtg tacactggga gcgccggttt ttctccaaaa ctgggtagag ttcaatttga
6181 aactgacaca gaccatgatt ttgaagctaa ccaaaacaca aagttcaccc cagttggtgt
6241 catccaagat ggtagcacca ctcaccgaaa tgaaccccaa cagtgggtgc tcccaagtta
6301 ctcaggcaga aatactccca atgtgcatct ggcccctgct gtagccccca cttttccggg
6361 tgagcaactt ctcttcttca ggtccaccat gcccggatgc agcgggtacc ctaacatgga
6421 tttggactgt ctgctccccc aggaatgggt gcagtacttc taccaagagg cagccccagc
6481 acaatctgat gtggctctgc taagatttgt gaatccagac acaggtaggg ttttgtttga
6541 gtgtaagctt cataaatcag gctatgttac agtggctcac actggccaac atgatttggt
6601 tatccccccc aatggctatt ttaggtttga ttcctgggtc aaccagtttt acacgcttgc
6661 ccccatggga aatggaacgg ggcgtagacg tgcactataa tggctggagc tttctttgct
6721 ggattggcat ctgatgtcct tggctctgga cttggttccc ttatcaatgc tggggctggg
6781 gccatcaacc aaaaagtcga gtttgaaaat aacagaaaat tgcaacaagc atccttccaa
6841 tttagcagca atctacaaca ggcttccttt caacatgaca aagagatgct ccaagcacaa
6901 attgaggcca ccaaaaggct acaacaggaa atgatgaaag ttaagcaggc agtgctccta
6961 gagggtgggt tctctgagac agatgcagcc cgcggggcaa tcaacgcccc catgacaaaa
7021 gctttggact ggagcgggac aaggtactgg gctcccgatg ctaggactac aacatacaat
7081 gcaggccgct tttctacccc tcaaccatca ggggcactgc caggaagagc taatcttagg
7141 gatgctgtcc ctgctcgggg ttcctccagt aagtcttcta actctttaac tgctacttct
7201 gtgtactcaa atcaaactac ttcaacgaga cttggttcta cagctggttc tggcaccagt
7261 gtctcgagct tcccgtcaac tgcaaggact aggagctggg ttgaggatca aagtaggaat
7321 ttgtcacctt tcatgagggg ggctcacaac atatcgtttg tcaccccacc atctagcaga
7381 tcctctagcc aaggcacagt ctcaaccgtg cctaaagaga ttttggactc ctggactggc
7441 gctttcaaca cgcgcaggca gccactcttc gctcacattc gtaagcgagg ggagtcacgg
7501 gcgtaa
//