Typing tool
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Typing tool
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Complete norovirus genomes
| MN307999 | GII.4 Sydney | |
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| GII.P31 |
ORF1: 1..5103
ORF2: 5084..6706
ORF3: 6706..7512
LOCUS MN307999 7512 bp RNA linear VRL 29-JUN-2021
DEFINITION Norovirus GII isolate 048_GII.Pe_GII.4_Araguaina nonstructural
polyprotein (ORF1), VP1 (ORF2), and VP2 (ORF3) genes, complete cds.
ACCESSION MN307999
VERSION MN307999.1
KEYWORDS .
SOURCE Norovirus GII
ORGANISM Norovirus GII
Viruses; Riboviria; Orthornavirae; Pisuviricota; Pisoniviricetes;
Picornavirales; Caliciviridae; Norovirus; Norovirus norwalkense.
REFERENCE 1 (bases 1 to 7512)
AUTHORS Tinker,R.J., da Costa,A.C., Tahmasebi,R., Milagres,F.A.P., Dos
Santos Morais,V., Pandey,R.P., Jose-Abrego,A., Brustulin,R.,
Rodrigues Teles,M.D.A., Cunha,M.S., Araujo,E.L.L., Gomez,M.M.,
Deng,X., Delwart,E., Sabino,E.C., Leal,E. and Luchs,A.
TITLE Norovirus strains in patients with acute gastroenteritis in rural
and low-income urban areas in northern Brazil
JOURNAL Arch Virol 166 (3), 905-913 (2021)
PUBMED 33462673
REFERENCE 2 (bases 1 to 7512)
AUTHORS Tinker,R.J., da-Costa,A.C., Leal,E.S., Tahmasebi,R.,
Milagres,F.A.P., Pandey,R.P., Jose-Abrego,A., Brustulin,R.,
Teles,Md.A.R., Sayao-Lobato,M.C.A.B., Chagas,R.T.,
Santos-Abrao,Md.F.N., Alves-Soares,C.V.D., Cunha,M.S., Deng,X.,
Delwart,E., Sabino,E.C. and Luchs,A.
TITLE Direct Submission
JOURNAL Submitted (13-AUG-2019) Institute of Tropical Medicine, University
of Sao Paulo, Av Dr Eneas de Carvalho Aguiar 470, Sao Paulo, Sao
Paulo 05403000, Brazil
COMMENT ##Assembly-Data-START##
Assembly Method :: Geneious v. R9
Sequencing Technology :: Illumina
##Assembly-Data-END##
FEATURES Location/Qualifiers
source 1..7512
/organism="Norovirus GII"
/mol_type="genomic RNA"
/isolate="048_GII.Pe_GII.4_Araguaina"
/isolation_source="feces"
/host="Homo sapiens"
/db_xref="taxon:122929"
/geo_loc_name="Brazil"
/collection_date="03-Feb-2016"
/note="genotype: GII.Pe_GII.4"
gene 1..5103
/gene="ORF1"
CDS 1..5103
/gene="ORF1"
/codon_start=1
/product="nonstructural polyprotein"
/protein_id="QED42385.1"
/translation="MKMASNDASAAAVANSNNDIAKSSSDGVFSNMAVTFKRALGARP
KQPPPKEVPPRPPRPPTPELVKKIPPPPPNGEDELVVSYSAKDGVSGLPELTTVRQPE
ETNTAFSVPPLNQRESRDAKEPLTGTIIEMWDGEIYHYGLYVERGLILGVHKPPAAIS
LAKVELAPLSLFWRPVYTPQYLISPDTLRRLHGESFPYTAFDNNCYAFCCWVLDLNDS
WLSRRMIQRTTGFFRPYQDWNRKPLPTMDDSKLKKVANIFLCTLSSLFTRPIKDIIGK
LKPLNILNILATCDWTFAGIVESLILLAELFGVFWTPPDVSAMIAPLLGDYELQGPED
LAVELVPIVMGGIGLVLGFTKEKIGKMLSSAASTLRACKDLGAYGLEILKLVMKWFFP
KKEEANELAMVRSIEDAVLDLEAIENNHMTTLLKDKDSLATYMRTLDLEEEKARKLST
KSASPDIVGTINSLLARIAAARSLVHRAKEELSSRPRPVVVMISGRPGIGKTHLAREL
AKKIAASLTGDQRVGLIPRNGVDHWDAYKGERVVLWDDYGMSNPIHDALRLQELADTC
PLTLNCDRIENKGKVFDSDAIIITTNLANPAPLDYVNFEACSRRIDFLVYAEAPEVEK
AKRDFPGQPDMWKNAFSPDFSHIKLSLAPQGGFDKNGNTPHGKGVMKTLTTGSLIARA
SGLLHERLDEYELQGPALTTFNFDRNKILAFRQLAAENKYGLMDTMRVGKQLKDVKTM
SDLKQALKNIAIKKCQIVYNGGTYTLEADGKGSVKVDKVQSATVQTNNELAGALHHLR
CARIRYYVKCVQEALYSIIQIAGAAFVTTRIAKRMNIQNLWSKPQVEDTEEMANKDGC
LQPKDDEEFVVSSDDIKTEGRKGKNKSGRGKKHTAFSSKGLSDEEYDEYKRIREERNG
KYSIEEYLQDRDRYYEEEVAIARATEEDFCEEEEAKIRQRIFRPTRKQRKEERASLGL
VTGSEIRKRNPEDFKPKGKLWADDDRSVDYNEKLNFEAPPSIWSRIVNFGSGWGFWVS
PSLFITSTHVIPQGAKEFFGVPIKQIQIHKSGEFCRLRFPKPIRTDVTGMILEEGAPE
GTVATLLIKRPTGELMPLAARMGTHATMKIQGRTVGGQMGMLLTGSNAKSMDLGTTPG
DCGCPYIYKRGNDYVAIGVHTAAARGGNTVICATQGSEGEATLEGGDSKGTYCGAPIL
GPGSAPKLSTKTKFWRSSTTPLPPGTYEPAYLGGKDPRVKGGPSLQQVMRDQLKPFTE
PRGKPPRPNVLEAAKKTIINVLEQTIDPPQKWSFAQACASLDKTTSSGHPHHMRKNDC
WNGESFTGKLADQASKANLMFEEGKNMTPVYTGALKDELVKTDKVYGKVKKRLLWGSD
LATMIRCARAFGGLMDELKAHCVTLPVRVGMNMNEDGPIIFEKHSRYRYHYDADYSRW
DSTQQRDVLAAALEIMVKFSPEPHLAQIVAEDLLSPSVMDVGDFQISISEGLPSGVPC
TSQWNSIAHWLLTLCALSEVTDLSPDIIQANSLFSFYGDDEIVSTDIKLDPEKLTAKL
KEYGLKPTRPDKTEGPLVISEDLDGLTFLRRTVTRDPAGWFGKLEQSSILRQMYWTRG
PNHEDPFETMIPHSQRPIQLMSLLGEAALHGPAFYSKISKLVIAELKEGGMDFYVPRQ
EPMFRWMRFSDLSTWEGDRNLAPSFVNEDGVE"
mat_peptide 1..990
/gene="ORF1"
/product="p48"
mat_peptide 991..2088
/gene="ORF1"
/product="NTPase"
mat_peptide 2089..2625
/gene="ORF1"
/product="p22"
mat_peptide 2626..3027
/gene="ORF1"
/product="VPg"
mat_peptide 3028..3570
/gene="ORF1"
/product="Pro"
mat_peptide 3571..5100
/gene="ORF1"
/product="RdRp"
gene 5084..6706
/gene="ORF2"
CDS 5084..6706
/gene="ORF2"
/note="major capsid protein"
/codon_start=1
/product="VP1"
/protein_id="QED42386.1"
/translation="MKMASSDANPSDGSAANLVPEVNNEVMALEPVVGAAIAAPVAGQ
QNVIDPWIRNNFVQAPGGEFTVSPRNAPGEILWSAPLGPDLNPYLSHLARMYNGYAGG
FEVQVILAGNAFTAGKVIFAAVPPNFPTEGLSPSQVTMFPHIVVDVRQLEPVLIPLPD
VRNNFYHYNQSNDPTIKLIAMLYTPLRANNAGDDVFTVSCRVLTRPSPDFDFIFLVPP
TVESRTKPFSVPVLTVEEMTNSRFPIPLEKLFTGPSSAFVVQPQNGRCTTDGVLLGTT
QLSPVNICTFRGDVTHITGSRNYTMNLASQNWSNYDPTEEIPAPLGTPDFVGKIQGML
TQTTRTDGSTRGHKATVYTGSAGFSPKLGRVQFETDTDHDFEANQNTKFTPVGVIQDG
STTHRNEPQQWVLPSYSGRNTPNVHLAPAVAPTFPGEQLLFFRSTMPGCSGYPNMDLD
CLLPQEWVQYFYQEAAPAQSDVALLRFVNPDTGRVLFECKLHKSGYVTVAHTGQHDLV
IPPNGYFRFDSWVNQFYTLAPMGNGTGRRRAL"
gene 6706..7512
/gene="ORF3"
CDS 6706..7512
/gene="ORF3"
/note="minor structural protein; small basic protein"
/codon_start=1
/product="VP2"
/protein_id="QED42387.1"
/translation="MAGAFFAGLASDVLGSGLGSLINAGAGAINQKVEFENNRKLQQA
SFQFSSNLQQASFQHDKEMLQAQIEATKRLQQEMMKVKQAVLLEGGFSETDAARGAIN
APMTKALDWSGTRYWAPDARTTTYNAGRFSTPQPSGALPGRANLRDAVPARGSSSKSS
NSLTATSVYSNQTTSTRLGSTAGSGTSVSSFPSTARTRSWVEDQSRNLSPFMRGAHNI
SFVTPPSSRSSSQGTVSTVPKEILDSWTGAFNTRRQPLFAHIRKRGESRA"
ORIGIN
1 ttgaagatgg cgtctaacga cgcttccgct gccgctgttg ccaacagcaa caacgacatc
61 gcaaaatctt caagtgacgg tgtgttttct aacatggctg tcacttttaa gcgggccctc
121 ggggcgcggc ctaaacagcc gcccccgaag gaagtaccac ccagaccccc gcgaccaccc
181 acaccagaat tggtcaaaaa gatccctcct cccccaccca acggggagga tgaactagtg
241 gtctcttaca gcgccaaaga tggcgtttcc ggattgcctg agctcaccac tgtcagacaa
301 ccggaagaaa ccaacacggc gttcagtgtc cccccactca accaaaggga gagcagggac
361 gccaaggagc cactaactgg aacaatcatt gaaatgtggg atggagaaat ctaccattac
421 ggcctgtacg tggaacgagg tcttatactt ggtgtgcaca agccaccggc agccattagc
481 cttgccaagg tcgagctagc accgctctct ttgttctgga gacctgtata caccccccag
541 tatctcatct ctccggacac tcttaggaga ttgcatggag agtcattccc ttacactgca
601 tttgacaaca attgctacgc attttgttgt tgggtattag acctaaacga ctcatggcta
661 agcaggagaa tgattcagag aacaacaggc ttctttaggc cgtaccagga ttggaacagg
721 aaacccctcc ccactatgga tgattccaag ttaaagaagg tagccaacat attcttgtgc
781 actttgtctt cactattcac cagacccatt aaggatataa tagggaagtt gaaacctctt
841 aacatcctta acattctggc tacatgtgat tggaccttcg caggcatagt ggaatcctta
901 atactcttgg cagaactctt tggagttttc tggacacccc cagatgtgtc tgcgatgatc
961 gcccccttgc taggtgatta tgaactgcaa ggacctgagg accttgcagt ggaactggtc
1021 ccaatagtga tgggggggat aggtttggtg ctaggattta ccaaagagaa aatcggaaag
1081 atgctatcat ccgctgcatc cactttaaga gcttgcaaag accttggtgc atacggactg
1141 gaaatcttaa aattggtcat gaagtggttc ttcccaaaga aagaggaagc aaatgaactg
1201 gctatggtga gatccatcga ggatgcagta ctagaccttg aggcaattga aaacaaccac
1261 atgaccaccc tactcaaaga caaagacagc ttggcaacct acatgagaac ccttgacctt
1321 gaggaggaga aagccagaaa actctcaacc aaatctgctt cacccgatat tgtgggcaca
1381 atcaactctc ttctggcaag aatcgctgct gcacgctccc tagtgcatcg ggcgaaagaa
1441 gagctttcca gcaggccgag acctgtcgtt gtgatgatat cgggaagacc agggataggg
1501 aaaactcacc ttgccaggga gctggccaag aagattgcgg cctccctcac aggggaccag
1561 cgtgtgggtc ttatcccacg caatggtgtc gaccactggg acgcatacaa gggcgaaaga
1621 gttgtcctat gggacgacta tggaatgagc aaccccatcc atgatgccct caggttacag
1681 gagcttgctg acacttgccc cctcacgcta aattgtgaca gaattgagaa caaagggaaa
1741 gtctttgaca gtgatgccat aattattacc accaatctgg ccaacccagc accactggat
1801 tatgttaact ttgaagcgtg ctcgagacgc attgatttcc tcgtgtacgc tgaagcccct
1861 gaggtggaga aggcaaagcg cgacttccca ggtcaacctg acatgtggaa gaacgctttc
1921 agtcctgact tctcacacat aaaactgtca ttggctccac agggtggttt tgacaagaat
1981 ggcaacaccc cgcatggaaa aggggtcatg aagaccctca ctactggctc cctcatcgcc
2041 cgagcatcag ggttactcca tgagaggcta gatgaatatg aactgcaagg cccggccctc
2101 accactttca actttgaccg caacaagata cttgctttta gacagcttgc tgctgaaaac
2161 aagtatgggc tgatggacac aatgagagtt ggaaaacaac tcaaggatgt caagaccatg
2221 tcagacctca aacaagcact caagaacatc gcgatcaaaa agtgccagat agtgtacaat
2281 ggtggcacct acacacttga ggctgatggc aagggtagtg tgaaagttga caaagtgcaa
2341 agtgccactg tgcagaccaa caatgaactt gccggtgccc tacaccacct aaggtgcgct
2401 agaatcagat actatgttaa gtgcgtccag gaggcactgt attccatcat ccaaatcgct
2461 ggggctgcat tcgtcaccac gcgcatcgct aagcgcatga atatacagaa tctctggtct
2521 aagccacagg tggaagacac agaagagatg gctaacaaag atggttgcct acaacccaaa
2581 gatgatgaag agtttgtcgt ctcatccgac gacatcaaaa ctgagggcag aaagggaaag
2641 aacaagtccg gccgtggcaa gaagcacaca gctttttcaa gtaaaggact cagtgatgag
2701 gagtacgatg agtacaagag gatcagagaa gaaaggaatg gtaagtactc catagaagag
2761 taccttcagg acagagacag gtactacgag gaggaggtgg ccattgccag ggcaaccgaa
2821 gaggacttct gtgaagaaga agaggccaaa atccggcaga gaattttcag gccaacaagg
2881 aaacaacgca aagaagagag ggcctctctc ggcttggtca caggctctga aatcaggaag
2941 agaaacccag aagacttcaa acccaaggga aagctgtggg ctgatgatga cagaagtgtt
3001 gactacaatg agaaactcaa ctttgaggcc ccaccaagca tctggtcgcg gatagtcaac
3061 tttggttcag gctggggctt ctgggtctcc cccagtctgt ttataacatc aacccatgtc
3121 ataccccaag gtgcaaaaga gttcttcgga gtccctatca agcaaatcca gatacacaag
3181 tcaggtgaat tctgccggtt gagattccca aagccaatca gaactgatgt gacgggcatg
3241 attctagaag aaggtgcgcc cgaggggacc gtggccacac tgctcatcaa gagaccaact
3301 ggagagctca tgcctctggc agccagaatg gggacccatg caaccatgaa aattcagggg
3361 cgcacagttg gaggacaaat gggtatgctc ctgacaggat ccaatgccaa gagtatggac
3421 ctaggcacaa caccaggcga ctgcggctgc ccctacatct acaagagggg gaatgactac
3481 gtggccatag gagtccatac ggccgctgcc cgtggaggaa acactgtcat atgtgccacc
3541 caggggagtg agggagaagc cacacttgaa ggaggtgaca gtaaagggac atactgtggc
3601 gcaccaatct tgggcccagg gagcgctccg aagctcagta ccaagactaa gttttggaga
3661 tcatccacaa caccactccc acctggcacc tacgaaccag cctacctcgg tggcaaagac
3721 cctagagtca aaggtggtcc ttcattgcag caagttatga gggaccagct gaagccattc
3781 acagaaccca gaggcaaacc gccaagacca aatgtattgg aagctgccaa gaaaaccatc
3841 atcaatgtcc ttgagcaaac aattgatcca cctcaaaaat ggtcatttgc gcaagcttgc
3901 gcatcccttg acaaaactac ctccagcggc cacccccacc acatgcggaa aaacgactgt
3961 tggaatgggg agtccttcac gggaaagttg gctgatcaag cctccaaggc caatctaatg
4021 tttgaagagg gaaagaacat gactccagtt tacacaggtg cacttaaaga tgagttggta
4081 aagaccgata aagtttatgg taaggtcaag aagaggcttc tgtggggttc agatctggcg
4141 accatgatac ggtgcgcccg agcttttgga ggccttatgg atgaactcaa ggcacactgt
4201 gtcacacttc ctgtcagagt tggtatgaac atgaatgagg atggccccat catctttgag
4261 aagcactcca gatatagata tcactatgat gctgattatt cccggtggga ttcaacacaa
4321 caaagggatg tgctagcagc agcactagaa atcatggtta agttctctcc agagccgcac
4381 ctggcccaga tagttgcaga agacctcctc tcccctagcg tgatggatgt aggtgacttt
4441 caaatatcaa taagtgaagg tctcccctct ggggtacctt gtacctccca gtggaattcc
4501 atcgcccact ggctcctcac tctgtgtgca ctctctgaag tcacggacct gtcccctgat
4561 atcattcagg ccaactccct tttctccttc tatggtgatg atgaaattgt aagcacagac
4621 ataaagttgg acccagagaa gctgacagca aaactcaagg agtacgggct gaaaccaacc
4681 cgccccgaca aaactgaagg accccttgtt atctctgaag acctggatgg cctgacattc
4741 ctccggagaa ctgtgacccg tgatccagct ggctggtttg gaaaattgga acaaagttca
4801 attctcaggc aaatgtactg gaccaggggt cccaaccatg aagatccatt tgaaacaatg
4861 ataccacact cccaaagacc catacaattg atgtccttgc tgggcgaggc tgcactccac
4921 ggcccggcat tctatagcaa aattagcaaa ttagtcattg cagagttgaa ggaaggtggc
4981 atggattttt acgtacccag acaagagcca atgttcagat ggatgagatt ctcagatctg
5041 agtacgtggg agggcgatcg caatctggct cccagttttg tgaatgaaga tggcgtcgag
5101 tgacgccaac ccatctgatg ggtccgcagc caacctcgtc ccagaggtca acaatgaggt
5161 tatggctctg gagcccgttg taggtgccgc cattgcggca cctgtagcgg gccaacaaaa
5221 tgtaattgac ccctggatta gaaataattt tgtacaagcc cctggtggag agtttacagt
5281 atcccctaga aacgctccag gtgaaatact atggagcgcg cccttgggcc ctgatctgaa
5341 tccctaccta tcccatttgg ccagaatgta caatggttat gcaggtggtt ttgaagtgca
5401 ggtaattctc gcggggaacg cgttcaccgc cgggaaggtc atatttgcag cagtcccacc
5461 aaattttcca actgaaggct tgagccccag ccaggtcact atgttccccc atatagtagt
5521 agatgttagg caactagaac ctgtgttgat tcccttaccc gatgttagga ataatttcta
5581 tcattacaat caatcaaatg accccactat taagttgata gcaatgttgt acacaccact
5641 tagggctaat aatgctgggg atgacgtctt cacagtttct tgccgagttc tcacgagacc
5701 atcccccgat tttgatttca tatttctagt gccacccaca gttgagtcaa gaactaaacc
5761 attctctgtc ccagttttaa ctgttgagga gatgaccaat tcaagattcc ccattccttt
5821 ggaaaagttg ttcacgggtc ccagcagtgc ctttgttgtc caaccacaaa acggtaggtg
5881 tacgactgat ggcgtgctcc taggcaccac ccaactgtcc cctgtcaaca tttgcacctt
5941 cagaggagat gtcacccata tcacaggtag tcgcaactac acaatgaatt tggcttctca
6001 gaattggagc aattatgacc caacagaaga aatcccagcc cctctaggaa ctccagattt
6061 tgtggggaag attcaaggca tgctcaccca aaccacaagg acagatggct cgacacgcgg
6121 ccacaaagcc acagtgtaca ctgggagcgc cggtttttct ccaaaactgg gtagagttca
6181 atttgaaact gacacagacc atgattttga agctaaccaa aacacaaagt tcaccccagt
6241 tggtgtcatc caagatggta gcaccactca ccgaaatgaa ccccaacagt gggtgctccc
6301 aagttactca ggcagaaata ctcccaatgt gcatctggcc cctgctgtag cccccacttt
6361 tccgggtgag caacttctct tcttcaggtc caccatgccc ggatgcagcg ggtaccctaa
6421 catggatttg gactgtctgc tcccccagga atgggtgcag tacttctacc aagaggcagc
6481 cccagcacaa tctgatgtgg ctctgctaag atttgtgaat ccagacacag gtagggtttt
6541 gtttgagtgt aagcttcata aatcaggcta tgttacagtg gctcacactg gccaacatga
6601 tttggttatc ccccccaatg gctattttag gtttgattcc tgggtcaacc agttttacac
6661 gcttgccccc atgggaaatg gaacggggcg tagacgtgca ctataatggc tggagctttc
6721 tttgctggat tggcatctga tgtccttggc tctggacttg gttcccttat caatgctggg
6781 gctggggcca tcaaccaaaa agtcgagttt gaaaataaca gaaaattgca acaagcatcc
6841 ttccaattta gcagcaatct acaacaggct tcctttcaac atgacaaaga gatgctccaa
6901 gcacaaattg aggccaccaa aaggctacaa caggaaatga tgaaagttaa gcaggcagtg
6961 ctcctagagg gtgggttctc tgagacagat gcagcccgcg gggcaatcaa cgcccccatg
7021 acaaaagctt tggactggag cgggacaagg tactgggctc ccgatgctag gactacaaca
7081 tacaatgcag gccgcttttc tacccctcaa ccatcagggg cactgccagg aagagctaat
7141 cttagggatg ctgtccctgc tcggggttcc tccagcaagt cttctaactc tttaactgct
7201 acttctgtgt actcaaatca aactacttca acgagacttg gttctacagc tggttctggc
7261 accagtgtct cgagcttccc gtcaactgca aggactagga gctgggttga ggatcaaagt
7321 aggaatttgt cacctttcat gaggggggct cacaacatat cgtttgtcac cccaccatct
7381 agcagatcct ctagccaagg cacagtctca accgtgccta aagagatttt ggactcctgg
7441 actggcgctt tcaacacgcg caggcagcca ctcttcgctc acattcgtaa gcgaggggag
7501 tcacgggcgt aa
//