Typing tool
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Typing tool
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Complete norovirus genomes
| MN307994 | GII.4 Sydney | |
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| GII.P31 |
ORF1: 1..5101
ORF2: 5082..6704
ORF3: 6704..7510
LOCUS MN307994 7510 bp RNA linear VRL 29-JUN-2021
DEFINITION Norovirus GII isolate 016_GII.Pe_GII.4_Paraiso do Tocantins
nonstructural polyprotein (ORF1) gene, partial cds; and VP1 (ORF2)
and VP2 (ORF3) genes, complete cds.
ACCESSION MN307994
VERSION MN307994.1
KEYWORDS .
SOURCE Norovirus GII
ORGANISM Norovirus GII
Viruses; Riboviria; Orthornavirae; Pisuviricota; Pisoniviricetes;
Picornavirales; Caliciviridae; Norovirus; Norovirus norwalkense.
REFERENCE 1 (bases 1 to 7510)
AUTHORS Tinker,R.J., da Costa,A.C., Tahmasebi,R., Milagres,F.A.P., Dos
Santos Morais,V., Pandey,R.P., Jose-Abrego,A., Brustulin,R.,
Rodrigues Teles,M.D.A., Cunha,M.S., Araujo,E.L.L., Gomez,M.M.,
Deng,X., Delwart,E., Sabino,E.C., Leal,E. and Luchs,A.
TITLE Norovirus strains in patients with acute gastroenteritis in rural
and low-income urban areas in northern Brazil
JOURNAL Arch Virol 166 (3), 905-913 (2021)
PUBMED 33462673
REFERENCE 2 (bases 1 to 7510)
AUTHORS Tinker,R.J., da-Costa,A.C., Leal,E.S., Tahmasebi,R.,
Milagres,F.A.P., Pandey,R.P., Jose-Abrego,A., Brustulin,R.,
Teles,Md.A.R., Sayao-Lobato,M.C.A.B., Chagas,R.T.,
Santos-Abrao,Md.F.N., Alves-Soares,C.V.D., Cunha,M.S., Deng,X.,
Delwart,E., Sabino,E.C. and Luchs,A.
TITLE Direct Submission
JOURNAL Submitted (13-AUG-2019) Institute of Tropical Medicine, University
of Sao Paulo, Av Dr Eneas de Carvalho Aguiar 470, Sao Paulo, Sao
Paulo 05403000, Brazil
COMMENT ##Assembly-Data-START##
Assembly Method :: Geneious v. R9
Sequencing Technology :: Illumina
##Assembly-Data-END##
FEATURES Location/Qualifiers
source 1..7510
/organism="Norovirus GII"
/mol_type="genomic RNA"
/isolate="016_GII.Pe_GII.4_Paraiso do Tocantins"
/isolation_source="feces"
/host="Homo sapiens"
/db_xref="taxon:122929"
/geo_loc_name="Brazil"
/collection_date="05-Jul-2013"
/note="genotype: GII.Pe_GII.4"
gene <1..5101
/gene="ORF1"
CDS <1..5101
/gene="ORF1"
/codon_start=2
/product="nonstructural polyprotein"
/protein_id="QED42370.1"
/translation="KMASNDASAAAVANSNNDIAKSSSDGVFSNMAVTFKRALGARPK
QPPPKEIPPRPPRPPTPELVKKIPPPPPNGEDELVVSYSAKDGVSGLPELTTVRQPEE
TNTAFSVPPLNQRESRDAKEPLTGTIIEMWDGEIYHYGLYVERGLILGVHKPPAAISL
AKVELTPLSLFWRPVYTPQYLISPDTLRRLHGESFPYTAFDNNCYAFCCWVLDLNDSW
LSRRMIQRTTGFFRPYQDWNRKPLPTMDDSKLKKVANIFLCTLSSLFTRPIKDIIGKL
KPLNILNILATCDWTFAGIVESLILLAELFGVFWTPPDVSAMIAPLLGDYELQGPEDL
AVELVPIVMGGIGLVLGFTKEKIGKMLSSAASTLRACKDLGAYGLEILKLVMKWFFPK
KEEANELAMVRSIEDAVLDLEAIENNHMTTLLKDKDSLATYMRTLDLEEEKARKLSTK
SASPDIVGTINSLLARIAAARSLVHRAKEELSSRPRPVVVMISGRPGIGKTHLARELA
KKIAASLTGDQRVGLIPRNGVDHWDAYKGERVVLWDDYGMSNPIHDALRLQELADTCP
LTLNCDRIENKGKVFDSDAIIITTNLANPAPLDYVNFEACSRRIDFLVYAEAPEVEKA
KRDFPGQPDMWKNAFSPDFSHIKLSLAPQGGFDKNGNTPHGKGVMKTLTTGSLIARAS
GLLHERLDEYELQGPALTTFNFDRNKILAFRQLAAENKYGLMDTMRVGKQLKDVKTMS
DLKQALKNIAIKKCQIVYNGSTYTLEADGKGSVKVDKVQSATVQTNNELAGALHHLRC
ARIRYYVKCVQEALYSIIQIAGAAFVTTRIAKRMNIQNLWSKPQVEDTEEMTNKDGCL
KPKDDEEFVVSSDDIKTEGKKGKNKSGRGKKHTAFSSKGLSDEEYDEYKRIREERNGK
YSIEEYLQDRDRYSSMEVAIARATEEDFCEEEEAKIRQRIFRPTRKQRKEERASLGLV
TGSEIRKRNPEDFKPKGKLWADDDRSVDYNEKLNFEAPPSIWSRIVNFGSGWGFWVSP
SLFITSTHVIPQGAKEFFGVPIKQIQIHKSGEFCRLRFPKPIRTDVTGMILEEGAPEG
TVATLLIKRPTGELMPLAARMGTHATMKIQGRTVGGQMGMLLTGSNAKSMDLGTTPGD
CGCPYIYKRGNDYVVIGVHTAAARGGNTVICATQGSEGEATLEGGDSKGTYCGAPILG
PGSAPKLSTKTKFWRSSTTPLPPGTYEPAYLGGKDPRVKGGPSLQQVMRDQLKPFTEP
RGKPPRPNVLEAAKKTIINVLEQTIDPPQKWSFAQACASLDKTTSSGHPHHMRKNDCW
NGESFTGKLADQASKANLMFEEGKNMTPVYTGALKDELVKTDKVYGKIKKRLLWGSDL
ATMIRCARAFGGLMDELKAHCVTLPVRVGMNMNEDGPIIFEKHSRYRYHYDADYSRWD
STQQRDVLAAALEIMVKFSPEPHLAQVVAEDLLSPSVMDVGDFQISISEGLPSGVPCT
SQWNSIAHWLLTLCALSEVTDLSPDIIQANSLFSFYGDDEIVSTDIKLDPEKLTAKLK
EYGLKPTRPDKTEGPLVISEDLDGLTFLRRTVTRDPAGWFGKLEQSSILRQMYWTRGP
NHEDPFETMIPHSQRPIQLMSLLGEAALHGPAFYSQLSKLVIAELKEGGMDFYVPRQE
PMFRWMRFSDLSTWEGDRNLAPSFVNEDGVE"
mat_peptide <1..988
/gene="ORF1"
/product="p48"
mat_peptide 989..2086
/gene="ORF1"
/product="NTPase"
mat_peptide 2087..2623
/gene="ORF1"
/product="p22"
mat_peptide 2624..3025
/gene="ORF1"
/product="VPg"
mat_peptide 3026..3568
/gene="ORF1"
/product="Pro"
mat_peptide 3569..5098
/gene="ORF1"
/product="RdRp"
gene 5082..6704
/gene="ORF2"
CDS 5082..6704
/gene="ORF2"
/note="major capsid protein"
/codon_start=1
/product="VP1"
/protein_id="QED42371.1"
/translation="MKMASSDANPSDGSAANLVPEVNNEVMALEPVVGAAIAAPVAGQ
QNVIDPWIRNNFVQAPGGEFTVSPRNAPGEILWSAPLGPDLNPYLSHLARMYNGYAGG
FEVQVILAGNAFTAGKVIFAAVPPNFPTEGLSPSQVTMFPHIVVDVRQLEPVLIPLPD
VRNNFYHYNQSNDPTIKLIAMLYTPLRANNAGDDVFTVSCRVLTRPSPDFDFIFLVPP
TVESRTKPFSVPVLTVEEMTNSRFPIPLEKLFTGPSSAFVVQPQNGRCTTDGVLLGTT
QLSPVNICTFRGDVTHITGSRNYTMNLASQNWNNYDPTEEIPAPLGTPDFVGKIQGVL
TQTTRTDGSTRGHKATVYTGSADFAPKLGRVQFETDTDHDFEANQNTKFTPVGVIQDG
STTHRNEPQQWVLPSYSGRNTHNVHLAPAVAPTFPGEQLLFFRSTMPGCSGYPNMDLD
CLLPQEWVQYFYQEAAPAQSDVALLRFVNPDTGRVLFECKLHKSGYVTVAHTGQHDLV
IPPNGYFRFDSWVNQFYTLAPMGNGTGRRRAV"
gene 6704..7510
/gene="ORF3"
CDS 6704..7510
/gene="ORF3"
/note="minor structural protein; small basic protein"
/codon_start=1
/product="VP2"
/protein_id="QED42372.1"
/translation="MAGAFFAGLASDVLGSGLGSLINAGAGAINQKVEFENNRKLQQA
SFQFSSNLQQASFQHDKEMLQAQIEATKKLQQEMMKVKQAMLLEGGFSETDAARGAIN
APMTKALDWSGTRYWAPDARTTTYNAGRFSTPQPSGALPGRANLRDAVPARGSSSKSS
NSSTATSVYSNQTTSTRLGSTAGSGTSVSSLPSTARTRSWVEDQSRNLSPFMRGAHNI
SFVTPPSSRSSSQGTVSTVPKEVLDSWTGAFNTRRQPLFAHIRKRGESRA"
ORIGIN
1 gaagatggcg tctaacgacg cttccgctgc cgctgttgcc aacagcaaca acgacatcgc
61 aaaatcttca agtgacggtg tgttttctaa catggctgtc acttttaagc gggccctcgg
121 ggcgcggcct aaacagccgc ccccgaagga gataccaccc agacccccgc gaccacccac
181 accagaattg gtcaaaaaga tccctcctcc cccacccaac ggggaggatg aactagtggt
241 ctcttacagc gccaaagatg gcgtttccgg actgcctgag ctcaccactg tcagacaacc
301 ggaagaaacc aacacggcgt tcagtgtccc cccactcaac caaagggaga gcagggacgc
361 caaggagcca ctaactggaa caattattga aatgtgggat ggagaaatct accattacgg
421 cctgtacgtg gaacgaggtc ttatacttgg tgtgcacaag ccaccggcag ccatcagcct
481 tgccaaggtc gagctaacac cgctctcttt gttctggaga cctgtataca ccccccagta
541 tctcatctct ccagacactc ttaggagatt acatggagag tcattcccct acactgcatt
601 tgacaacaat tgctacgcct tttgttgttg ggtattagac ctaaacgact catggctaag
661 caggagaatg attcagagaa caacaggttt cttcaggccg taccaggatt ggaacaggaa
721 acccctcccc actatggatg attccaaatt aaagaaggta gccaacatat tcttgtgcac
781 tttgtcttca ctattcacca gacccattaa ggacataata gggaagttga aacctcttaa
841 catccttaac attctggcta catgtgattg gaccttcgca ggcatagtgg aatccttaat
901 actcttagca gaactctttg gagttttctg gacaccccca gatgtgtctg cgatgatcgc
961 ccccttgcta ggtgattatg aactgcaagg acctgaggac cttgcagtgg aactggtccc
1021 aatagtgatg ggggggatag gtttggtgct aggatttacc aaagagaaaa ttggaaagat
1081 gctatcatcc gctgcatcca ctttaagagc ttgtaaagac cttggtgcat acggactgga
1141 aatcttaaaa ttggtcatga agtggttctt cccaaagaaa gaggaagcaa atgaactggc
1201 tatggtgaga tccatcgagg acgcagtgct agacctcgag gcaattgaaa acaaccacat
1261 gaccacccta ctcaaagaca aagacagctt ggcaacctac atgagaaccc ttgaccttga
1321 ggaggagaaa gccagaaaac tctcaaccaa atctgcttca cccgatattg tgggcacaat
1381 caactctctt ttggcaagaa tcgctgctgc acgctcccta gtgcatcggg cgaaagaaga
1441 gctctccagc aggccgagac ctgtcgttgt gatgatatcg ggaagaccag ggatagggaa
1501 aactcacctt gccagggagc tggccaagaa gatcgcggcc tccctcacag gggaccagcg
1561 tgtgggtctt atcccacgca atggtgtcga tcactgggac gcatacaagg gcgaaagagt
1621 tgtcctatgg gacgactatg gaatgagcaa ccccatccat gatgccctca ggttgcagga
1681 gcttgctgac acttgccccc tcacgctaaa ttgtgacaga attgagaaca aagggaaagt
1741 ctttgacagt gatgccataa ttatcaccac caatctggcc aacccagcac cactggatta
1801 tgtcaacttt gaagcgtgct cgagacgtat tgacttcctc gtgtacgcag aagcccctga
1861 ggtggagaag gcaaagcgcg acttcccagg tcaacctgat atgtggaaga acgctttcag
1921 tcctgacttc tcacacataa aactgtcatt ggctccacag ggtggttttg acaagaacgg
1981 caacaccccg catggaaaag gggtcatgaa gaccctcacc actggctccc tcatcgcccg
2041 agcatcaggg ttgctccatg agaggctaga tgaatatgaa ctgcaaggcc cagccctcac
2101 cactttcaac tttgaccgca acaagatact tgcttttaga cagcttgctg ctgaaaacaa
2161 gtatgggctg atggacacaa tgagagttgg aaaacagctc aaggatgtca agaccatgtc
2221 agacctcaaa caagcactca agaacatcgc gatcaagaag tgccagatag tgtacaatgg
2281 tagcacctac acacttgagg ccgatggcaa gggtagtgtg aaagttgaca aagtgcaaag
2341 tgccactgtg cagaccaaca atgaactagc cggtgcccta caccacctaa ggtgcgctag
2401 aatcagatac tatgttaagt gcgtccagga ggcactgtat tccatcatcc aaatcgctgg
2461 ggctgcattc gtcaccacgc gcatcgctaa gcgcatgaat atacagaatc tctggtccaa
2521 gccacaggtg gaagacacag aagagatgac caacaaagat ggttgcctaa aacccaaaga
2581 tgatgaagag tttgtcgtct catccgacga catcaaaact gagggcaaga aagggaagaa
2641 caagtccggc cgtggcaaga agcacacagc cttttcaagc aaagggctca gtgatgagga
2701 gtacgatgag tacaagagaa tcagagaaga aaggaatggt aagtactcca tagaagagta
2761 ccttcaggac agagacaggt actcttctat ggaggtggcc atcgccaggg caaccgaaga
2821 ggacttctgt gaagaagaag aggccaaaat ccggcagaga attttcagac caacaaggaa
2881 acaacgcaaa gaagagaggg cctctctcgg cttggtcaca ggctctgaaa tcaggaagag
2941 aaacccagaa gacttcaaac ccaagggaaa gctgtgggct gatgatgaca gaagtgttga
3001 ctacaatgag aaactcaact ttgaggcccc accaagcatc tggtcgcgga tagtcaactt
3061 tggttcaggc tggggcttct gggtctcccc cagtctgttt ataacatcaa cccatgtcat
3121 accccaaggt gcaaaagagt tcttcggagt ccctatcaag caaatccaga tacacaaatc
3181 aggtgaattc tgccggttga gattcccaaa gccaatcaga actgatgtga cgggcatgat
3241 tctagaagaa ggtgcgcccg aggggaccgt ggccacactg ctcatcaaga gaccaactgg
3301 agagctcatg cctctggcag ccagaatggg aacccatgca accatgaaaa ttcaggggcg
3361 cacagttgga gggcaaatgg gtatgctcct gacaggatcc aacgccaaga gtatggacct
3421 aggcacaaca ccaggcgact gcggctgccc ctacatctac aagaggggga atgactacgt
3481 ggtcatagga gtccatacgg ccgctgcccg tggaggaaac actgtcatat gtgccaccca
3541 ggggagtgag ggagaagcca cacttgaagg aggtgacagt aaagggacat actgtggcgc
3601 accaatcttg ggcccaggga gcgctccgaa gctcagtacc aagactaagt tttggagatc
3661 atccacaaca ccactcccac ctggcaccta cgaaccagcc tacctcggtg gcaaagaccc
3721 cagagtcaaa ggtggccctt cattgcaaca agttatgagg gaccagctaa agccattcac
3781 agaacccaga ggcaaaccac caagaccaaa tgtgttggaa gctgccaaga aaaccatcat
3841 caatgtcctt gagcaaacaa ttgatccacc ccaaaaatgg tcatttgcgc aagcttgcgc
3901 atcccttgac aaaaccacct ccagcggcca cccgcaccac atgcggaaaa acgattgttg
3961 gaatggggag tccttcacag gaaaattggc tgatcaagcc tccaaggcca acctaatgtt
4021 tgaagaggga aagaacatga ctccagtcta cacaggtgca cttaaagatg agttggtaaa
4081 gaccgataaa gtttatggta agatcaagaa gaggcttctg tggggttcag atctggcgac
4141 catgatacgg tgcgcccgag cttttggagg ccttatggat gaactcaagg cgcactgtgt
4201 cacacttcct gtcagagttg gtatgaacat gaatgaggat ggccccatca tctttgagaa
4261 gcattccaga tatagatatc actatgatgc tgattattcc cggtgggact caacacaaca
4321 aagggatgtg ctagcagcag cactagaaat catggttaag ttctctccag aaccacacct
4381 ggcccaggta gttgcagaag acctcctttc ccctagcgta atggatgtag gtgactttca
4441 aatatcaata agtgagggtc ttccctctgg ggtaccttgc acctcccagt ggaattccat
4501 cgcccactgg ctcctcactc tttgtgcact ctctgaagtc acggacctgt cccctgacat
4561 cattcaggcc aactcccttt tctccttcta tggtgatgat gagattgtaa gcacagacat
4621 aaagttggac ccagagaagc tgacagcaaa actcaaggag tacgggctga aaccaacccg
4681 ccccgacaaa actgaaggac cccttgttat ctctgaagac ctggatggcc tgacattcct
4741 ccggagaact gtgacccgtg atccagctgg ctggtttgga aaattggaac aaagttcaat
4801 tctcagacaa atgtactgga ccaggggtcc caaccatgaa gatccatttg aaacaatgat
4861 accacactcc caaagaccca tacaattgat gtccttgctg ggcgaggctg cactccacgg
4921 cccggcattc tacagccaac tcagcaaact agtcattgca gagttgaagg aaggtggcat
4981 ggatttttac gtgcccagac aagagccaat gttcagatgg atgagattct cagatctgag
5041 cacatgggag ggcgatcgca atctggctcc cagttttgtg aatgaagatg gcgtcgagtg
5101 acgccaaccc atctgatggg tccgcagcca acctcgtccc agaggtcaac aatgaggtta
5161 tggctctgga gcccgttgtt ggtgccgcca ttgcggcacc tgtagcgggc caacaaaatg
5221 taattgaccc ctggattaga aacaattttg tacaagcccc tggtggagag tttacagtat
5281 cccctagaaa cgctccaggt gaaatactat ggagcgcgcc cttgggccct gatctaaatc
5341 cctacctatc ccatttggcc agaatgtaca atggttatgc aggtggtttt gaagtgcagg
5401 tgattctcgc ggggaacgcg ttcaccgccg ggaaggtcat atttgcagca gtcccaccaa
5461 attttccaac tgaaggcttg agccccagcc aggtcactat gttcccccat atagtagtag
5521 atgttaggca actagaacct gtgttgattc ccttacccga tgttaggaat aatttctatc
5581 attataatca atcaaatgac cccaccatta agttgatagc aatgttgtat acaccactta
5641 gggctaataa tgctggggat gatgtcttca cagtttcttg ccgagttctc acgagaccat
5701 cccccgattt tgatttcata tttctagtgc cacccacagt tgagtcaaga actaaaccat
5761 tctctgtccc agttttaact gttgaggaga tgaccaattc aagattcccc attcctttgg
5821 aaaagttgtt cacgggtccc agcagtgcct ttgttgtcca accacaaaac ggcaggtgca
5881 cgactgatgg cgtgctccta ggcaccaccc aactgtctcc tgtcaacatt tgcaccttca
5941 gaggagatgt cacccatatc acaggtagtc gcaactacac aatgaatttg gcttctcaaa
6001 attggaacaa ttatgaccca acagaagaaa tcccagcccc tctaggaact ccagactttg
6061 tggggaagat tcaaggcgtg ctcacccaaa ccacaaggac agatggctca acacgcggcc
6121 acaaagccac agtgtacact gggagcgccg actttgctcc aaaactgggt agagttcaat
6181 ttgaaactga cacagaccat gattttgagg ctaaccaaaa cacaaagttc accccagtcg
6241 gtgtcatcca agatggtagc accacccacc gaaatgaacc ccaacagtgg gtgctcccaa
6301 gttactcagg cagaaatacc cataatgtgc atctggcccc cgctgtagcc cccacttttc
6361 cgggtgagca acttctcttc ttcagatcca ccatgcccgg atgcagcggg taccccaaca
6421 tggatttgga ctgtctgctc ccccaggaat gggtgcagta cttctaccaa gaggcagccc
6481 cagcacaatc tgatgtggct ctgctaagat ttgtgaatcc agacacaggt agggttttgt
6541 ttgagtgtaa gcttcataaa tcaggctatg ttacagtggc tcacactggc caacatgatt
6601 tggttattcc ccccaatggt tattttagat ttgattcctg ggtcaaccag ttctacacgc
6661 ttgcccccat gggaaatgga acggggcgta gacgtgcagt ataatggctg gagctttctt
6721 tgctggattg gcatctgatg tccttggctc tggacttggt tcccttatca atgctggggc
6781 tggggccatc aaccaaaaag ttgagtttga aaataacaga aaattgcaac aagcatcctt
6841 ccaatttagc agcaatctac aacaggcttc ctttcaacat gacaaagaga tgctccaagc
6901 acaaattgag gccaccaaaa agctacaaca ggaaatgatg aaagttaagc aggcaatgct
6961 cctagagggt gggttctctg agacagacgc agcccgcggg gcaatcaacg cccccatgac
7021 aaaagctttg gactggagcg ggacaaggta ctgggctccc gatgctagga ctacaacata
7081 caatgcaggc cgcttttcca cccctcaacc atcgggggca ctgccaggaa gagctaatct
7141 tagggatgct gtccctgctc ggggttcctc cagtaaatct tctaactctt ctactgctac
7201 ttctgtgtac tcaaatcaaa ctacttcaac gagacttggt tctacagctg gttctggtac
7261 cagtgtctcg agcctcccgt caactgcaag gactaggagc tgggttgagg atcaaagtag
7321 gaatttgtca cctttcatga ggggggccca caacatatcg tttgtcaccc caccatctag
7381 cagatcctct agccaaggca cagtctcaac cgtgcctaaa gaggttttgg actcctggac
7441 tggcgctttc aacacgcgca ggcagccact cttcgctcac attcgtaagc gaggggagtc
7501 acgggcgtaa
//