Typing tool
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Typing tool
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Complete norovirus genomes
| MK789434 | GII.4 Sydney | |
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| GII.P4 New Orleans |
ORF1: 1..5093
ORF2: 5074..6696
ORF3: 6696..7502
LOCUS MK789434 7540 bp RNA linear VRL 20-APR-2019
DEFINITION Norovirus GII isolate 3546 nonstructural polyprotein (ORF1) gene,
partial cds; and VP1 (ORF2) and VP2 (ORF3) genes, complete cds.
ACCESSION MK789434
VERSION MK789434.1
KEYWORDS .
SOURCE Norovirus GII
ORGANISM Norovirus GII
Viruses; Riboviria; Orthornavirae; Pisuviricota; Pisoniviricetes;
Picornavirales; Caliciviridae; Norovirus; Norwalk virus.
REFERENCE 1 (bases 1 to 7540)
AUTHORS Santiso-Bellon,C., Fuentes-Trillo,A., Vila-Vicent,S., Monzo,C., da
Silva Ribeiro de Andrade,J., Gozalbo Rovira,R., Buesa,J.,
Chaves,F.J. and Rodriguez-Diaz,J.
TITLE Nearly Complete Genome Sequences of Human Norovirus from Valencia
(Spain)
JOURNAL Unpublished
REFERENCE 2 (bases 1 to 7540)
AUTHORS Santiso-Bellon,C., Fuentes-Trillo,A., Vila-Vicent,S., Monzo,C., da
Silva Ribeiro de Andrade,J., Gozalbo Rovira,R., Buesa,J.,
Chaves,F.J. and Rodriguez-Diaz,J.
TITLE Direct Submission
JOURNAL Submitted (12-APR-2019) Microbiology and Ecology, University of
Valencia, Avenida Blasco Ibanez 17, Valencia, Valencia 46010, Spain
COMMENT ##Assembly-Data-START##
Assembly Method :: SPAdes v. v3.11.1; MEGAHIT with CD-HIT v.
v1.1.3
Sequencing Technology :: Illumina
##Assembly-Data-END##
FEATURES Location/Qualifiers
source 1..7540
/organism="Norovirus GII"
/mol_type="genomic RNA"
/isolate="3546"
/isolation_source="stool sample"
/host="Homo sapiens"
/db_xref="taxon:122929"
/country="Spain: Valencia"
/collection_date="Sep-2016"
/note="genotype: GII.P4.NewOrleans2009_GII.4.Sydney2012"
gene <1..5093
/gene="ORF1"
CDS <1..5093
/gene="ORF1"
/codon_start=3
/product="nonstructural polyprotein"
/protein_id="QCA41770.1"
/translation="ASNDASAAAVANSNNDTAKSSSDGVLSSMAVTFKRALGARPKQP
PPREKSQRPPRPPTPELVKNIPPPPPNGEDEIVVSYSVKDGVSGLPDLSTVRQPEESN
TAFSVPPLNQRENRDAKEPLTGTILEMWDGEIYHYGLYVERGLVLGVHKPPAAISLAK
VELAPLSLYWRPVYTPQYLISPDTLKKLSGETFPYTAFDNNCYAFCCWVLDLNDSWLS
RRMIQRTTGFFRPYQDWNRKPLPTMDDSKIKKVANIFLCALSSLFTRPIKDIIGKIRP
LNILNILASCDWTFAGIVESLILLAELLGVFWTPPDVSAMIAPLLGDYELQGPEDLAV
ELVPVVMGGIGLVLGFTKEKIGKMLSSAASTLRACKDLGAYGLEILKLVMKWFFPKKE
EANELAIVRSIEDAVLDLEAIENNHMTTLLKDKDSLATYMRTLDLEEEKARKLSTKSA
SPDIVGTINALLARIAAARSLVHRAKEELSSRPRPVVLMISGRPGIGKTHLAREVAKR
IAASLTGDQRVGLIPRNGVDHWDAYKGERVVLWDDYGMSNPIHDALRLQELADTCPLT
LNCDRIENKGKVFDSDVIIITTNLANPAPLDYVNFEACSRRIDFLVYAEAPDVEKAKR
DFPGQPDMWKNAFSSDFSHIKLALAPQGGFDKNGNTPHGKGVMKTLTTGSLIARASGL
LHERLDEFELQGPALTTFNFDRNKVLAFRQLAAENKYGLMDTMRVGKQLRDVKTMPEL
KQALKNVSIKKCQIVYSGCTYMLESDGKGNVKVDRIQSAAVQTNNELAGALHHLRCAR
IRYYVKCVQEALYSIIQIAGAAFVTTRIAKRMNIQDLWSKPQVENTEETTSKDGCPKP
KDDEEFVISSDDIKTEGKKGKNKTGRGKKHTAFSSKGLSDEEYDEYKRIREERNGKYS
IEEYLQDRDKYYEEVAIARATEEDFCEEEEAKIRQRIFRPTRKQRKEERVSLGLVTGS
EIRKRNPDDFKPKGKLWADDDRSVDYNEKLSFEAPPSIWSRIVNFGSGWGFWVSPSLF
ITSTHVIPQGAKEFFGVPIKQIQVHKSGEFCRLRFPKPIRTDVTGMILEEGAPEGTVV
TLLIKRSTGELMPLAARMGTHATMKIQGRTVGGQMGMLLTGSNAKSMDLGTTPGDCGC
PYIYKRGNDYVVIGVHTAAARGGNTVICATQGSEGEATLEGGDNKGTYCGAPILGPGS
APTLSTKTKFWRSSTASLPPGTYEPAYLGGKDPRVKGGPSLQQVMREQLKPFTEPRGK
PPKPSVLEAAKKTIINVLEQTIDPPEKWSFAQACASLDKTTSSGHPHHMRKNDCWNGE
SFTGKLADQASKANLMFEEGKNMTPVYTAALKDELVKTDKIYGKIKKRLLWGSDLATM
IRCARAFGGLMDELKAHCVTLPIRVGMNMNEDGPIIFERHSRYTYHYDADYSRWDSTQ
QRAVLAAALEIMVKFSPEPHLAQVVAEDLLSPSVVDVGDFTISINEGLPSGVPCTSQW
NSIAHWLLTLCALSEVTNLSPDTIQANSLFSFYGDDEIVSTDIKLDPEKLTAKLKEYG
LKPTRPDKTEGPLVISEDLDGLTFLRRTVTRDPAGWFGKLEQSSILRQMYWTRGPNHG
DPSETMIPHSQRPIQLMSLLGEAALHGPAFYSKISKLVIAELKEGGMDFYVPRQEPMF
RWMRFSDLSTWEGDRNLAPSFVNEDGVE"
mat_peptide <1..983
/gene="ORF1"
/product="p48"
mat_peptide 984..2081
/gene="ORF1"
/product="NTPase"
mat_peptide 2082..2618
/gene="ORF1"
/product="p22"
mat_peptide 2619..3017
/gene="ORF1"
/product="VPg"
mat_peptide 3018..3560
/gene="ORF1"
/product="Pro"
mat_peptide 3561..5090
/gene="ORF1"
/product="RdRp"
gene 5074..6696
/gene="ORF2"
CDS 5074..6696
/gene="ORF2"
/note="major capsid protein"
/codon_start=1
/product="VP1"
/protein_id="QCA41771.1"
/translation="MKMASSDANPSDGSAANLVPEVNNEVMALEPVVGAAIAAPVAGQ
QNVIDPWIRNNFVQAPGGEFTVSPRNAPGEILWSAPLGPDLNPYLSHLARMYNGYAGG
FEVQVILAGNAFTAGKVIFAAVPPNFPTEGLSPSQVTMFPHIVVDVRQLEPVLIPLPD
VRNNFYHYNQSNDPTIKLIAMLYTPLRANNAGDDVFTVSCRVLTRPSPDFDFIFLVPP
TVESRTKPFSVPVLTVEEMTNSRFPIPLEKLFTGPSSAFVVQPQNGRCTTDGVLLGTT
QLSPVNICTFRGDVTHITGSRNYTMNLASQNWNNYDPTEEIPAPLGAPDFVGKIQGML
TQTTRADGSTRGHKATVYTGSADFAPKLGRVQFETDTDHDFEASQNTKFTPVGVIQDG
STTHRNEPQQWVLPSYSGRNTHNVHLAPAVAPTFPGEQLLFFRSTMPGCSGYPNMDLD
CLLPQEWVQYFYQEAAPAQSDVALLRFVNPDTGRVLFECKLHKSGYVTVAHTGQHDLV
IPPNGYFRFDSWVNQFYTLAPMGNGAGRRRVV"
gene 6696..7502
/gene="ORF3"
CDS 6696..7502
/gene="ORF3"
/note="minor structural protein; small basic protein"
/codon_start=1
/product="VP2"
/protein_id="QCA41772.1"
/translation="MAGAFFAGLASDVLGSGLGSLINAGAGAINQKVEFENNRKLQQA
SFQFSSNLQQASFQHDKEMLQAQIEATKKLQQEMMKVKQAMLLEGGFSETDAARGAIN
APMTKALDWSGTRYWAPDARTTTYNAGRFSTPQPSGALPGRTNLRDTVPARGSSSKSF
NSSTVTSVHSNQTTSTRLGSTAGSGTSVSSLPSTARTRSWVEDQSRSLSPFMRGAHNI
SFVTPPSSRSSSQGTVSTVPKEVLDSWTGAFNTRRQPLFAHIRKRGESRV"
ORIGIN
1 tggcgtctaa cgacgcttcc gctgccgctg ttgctaacag caacaacgac accgcaaaat
61 cttcaagtga cggagtgctt tctagcatgg ctgtcacttt taaacgagcc ctcggggcgc
121 ggcctaaaca gcctcccccg agggaaaaat cacaaagacc cccacgacca cccacaccag
181 aactggttaa aaatattccc ccccccccac ccaacggaga ggacgaaata gtggtttctt
241 atagtgttaa agatggtgtt tccggcttgc ctgacctttc caccgtcagg cagccggaag
301 aatccaacac ggccttcagt gtccctccac tcaatcagag ggagaataga gatgctaagg
361 aaccactcac tggaacaatt ctggaaatgt gggacgggga gatctaccat tatggcctgt
421 atgtggagcg aggtcttgta ctaggcgtgc acaaaccccc agctgccatc agcctcgcta
481 aggttgagtt agcaccactt tccttgtact ggagacctgt gtacactcct cagtacctta
541 tctctccgga cactctcaag aaattgtccg gagaaacgtt cccctacaca gcctttgaca
601 acaactgcta tgccttttgt tgctgggtcc tggacctaaa tgactcgtgg ctgagcagga
661 gaatgatcca gagaacaact ggtttcttca ggccctacca agactggaat aggaaacccc
721 tccccactat ggatgactcc aaaataaaga aggtggctaa catatttctg tgtgctctgt
781 cctcgctatt caccaggccc ataaaagata taatagggaa gataaggcct cttaacatcc
841 tcaacatctt agcctcatgt gattggacct ttgcgggcat agtggagtcc ctgatactct
901 tggcagaact ccttggagtt ttctggacac ccccagatgt gtctgcgatg attgccccct
961 tacttggtga ctacgagcta caaggacctg aggaccttgc agtggagctc gtccccgtgg
1021 tgatgggggg aattggtttg gtgctaggat tcaccaaaga aaagattggg aaaatgttgt
1081 catcagctgc gtccacctta agagcttgca aagaccttgg tgcgtatggg ctagagatcc
1141 taaagttagt catgaagtgg ttcttcccga agaaggagga ggcaaatgag ctggctatag
1201 tgaggtccat cgaggatgca gtcctggatc tcgaagcaat tgaaaacaat catatgacca
1261 ccttgctcaa agataaagac agtctggcaa cctacatgag aacacttgac cttgaagagg
1321 agaaagccag gaaactctca accaaatctg cctcacccga tatcgtgggc acaatcaacg
1381 ccctcctggc gagaatcgct gccgcacgtt ctctggtgca tcgagcgaag gaggagcttt
1441 ccagcagacc aagacctgtg gtgttgatga tatcaggcag gccaggaata gggaagaccc
1501 accttgctag ggaagtggct aagagaatcg cagcctccct tacaggagac caacgtgttg
1561 gtctcatccc acgcaatggc gtcgaccatt gggatgcgta caagggggag agggtcgtcc
1621 tatgggacga ttatggaatg agcaacccta ttcacgatgc cctcaggctg caagaactcg
1681 ctgacacttg ccccctcact ctgaactgtg acaggattga aaataaagga aaggtctttg
1741 acagcgatgt catcattatc accaccaatc tggccaaccc agccccactg gactatgtca
1801 actttgaagc atgctcgagg cgcattgact tcctcgtgta tgcagaagcc cctgatgtcg
1861 aaaaggcgaa gcgtgacttc ccaggccaac ctgacatgtg gaagaacgct ttcagttctg
1921 atttctcaca cataaaacta gcactggccc cacagggtgg tttcgacaag aacgggaaca
1981 ccccacacgg aaagggcgtc atgaagactc tcaccactgg ctcccttatt gcccgggcat
2041 cagggctact ccatgagagg ttagatgaat ttgaactgca gggtccagct ctcaccacct
2101 tcaatttcga tcgcaataaa gtgcttgcct ttagacagct tgctgctgaa aataaatatg
2161 gattgatgga cacaatgagg gttgggaaac agctcaggga tgtcaaaacc atgccagaac
2221 tcaaacaagc actcaagaat gtctcaatca agaagtgtca aatagtgtat agtggttgca
2281 cctacatgct tgagtctgat ggcaagggca atgtgaaagt tgacaggatc caaagcgccg
2341 ccgtgcagac caacaatgag ctggctggtg ccctgcacca cttgaggtgc gccagaatca
2401 gatactatgt caagtgtgtc caggaagccc tgtattccat cattcaaatt gctggggctg
2461 catttgtcac cacgcgcatt gccaagcgca tgaacataca ggacctatgg tccaagccac
2521 aagtggaaaa cacagaggag actaccagca aggacgggtg cccaaaacct aaggatgatg
2581 aggagtttgt catttcatcc gacgacatca aaactgaggg caagaaaggg aagaacaaga
2641 ctggccgtgg caagaagcac acagcatttt caagcaaagg cctcagtgat gaagagtacg
2701 atgaatacaa gaggatcagg gaagaaagga atggcaagta ctctatagaa gagtaccttc
2761 aggacaggga caaatactat gaagaggtgg ccattgccag agcgactgag gaagacttct
2821 gtgaagagga ggaagccaag atccgacaaa ggatctttag gccaacaagg aaacaacgca
2881 aggaggaaag agtctctctc ggtttggtca caggttctga aattaggaaa agaaacccag
2941 atgacttcaa acccaagggg aaattgtggg ctgacgatga caggagtgtg gactacaatg
3001 agaaactcag ttttgaggcc ccgccaagca tttggtcaag aatagtcaac tttggttcag
3061 gctggggatt ctgggtctcc cccagcttgt tcataacatc aacccatgtt ataccccagg
3121 gcgcaaagga gttctttgga gtccccatca aacaaataca ggtacacaag tcaggcgagt
3181 tctgtcgctt gagattccct aaaccaatta ggactgatgt gacgggcatg atcttagaag
3241 aaggcgcacc tgagggcacc gtggttacac tactcatcaa aaggtccact ggggaactta
3301 tgcccctagc agctaggatg gggacccatg cgaccatgaa gatccaaggg cgcactgttg
3361 ggggccagat gggcatgctt ctgacaggat ccaacgccaa gagtatggac ctgggtacca
3421 cgccaggtga ttgtggctgc ccctacatct ataagagagg taacgactat gtggtcattg
3481 gggtccacac ggctgccgca cgcgggggga acactgtcat atgtgccacc caggggagtg
3541 aaggagaggc tacacttgag ggtggtgaca acaaggggac atactgtggt gcaccaatcc
3601 taggcccagg gagtgcccca acacttagca ccaagaccaa attctggagg tcgtccacag
3661 catcactccc acctggcacc tatgaaccag cctatcttgg tggcaaggac cctagagtca
3721 agggtggccc ttcgctgcag caagtcatga gggaacagtt gaagccattc acggagccca
3781 ggggtaagcc accaaagcca agtgtgttag aagctgccaa gaaaaccatc attaatgtcc
3841 ttgagcaaac aattgatcca cctgagaaat ggtcgttcgc acaagcttgc gcgtctcttg
3901 acaagaccac ttccagtggc catccgcacc acatgcggaa aaacgactgc tggaacgggg
3961 agtccttcac aggcaagctg gcagaccagg cttctaaagc caacctgatg tttgaagaag
4021 ggaagaacat gaccccagtc tacacagctg cgctcaagga tgagttagtt aaaactgaca
4081 agatttatgg taagatcaag aagaggcttc tttggggctc ggacttggcg accatgatcc
4141 ggtgtgctcg agcattcgga ggcctaatgg atgaactcaa agcgcattgt gtcacacttc
4201 ccattagagt tggcatgaat atgaatgagg atggccctat catctttgag aggcattcca
4261 ggtacacgta ccactatgat gctgattact ctcgatggga ttcaacacaa cagagagccg
4321 tgttggcagc agctttagaa atcatggtaa aattctcccc agaaccacat ttggctcagg
4381 tagttgctga agaccttctt tctcctagcg tggtggacgt gggcgacttc acaatatcaa
4441 tcaacgaggg cctcccctct ggggtgcctt gcacctccca atggaactcc atcgcccact
4501 ggcttctcac tctctgtgcg ctctccgaag tcacaaacct gtctcctgat accatacagg
4561 ctaattccct cttctctttt tatggtgatg atgaaattgt tagcacagac ataaaattgg
4621 acccagagaa attgacagca aagctcaaag aatatgggct aaagccaacc cgccctgaca
4681 aaactgaagg accccttgtc atctctgaag acctggatgg cctaactttc ctgcggagaa
4741 ctgtgacccg cgacccagct ggttggtttg gaaaactgga gcagagctca atactcaggc
4801 aaatgtactg gactaggggt cccaaccatg gagacccatc tgaaacaatg attccacact
4861 cccaaagacc catacaattg atgtccctac tgggggaggc cgctctccac ggcccagcat
4921 tttacagtaa aattagtaaa ttggtcattg cagagctaaa agaaggtggt atggattttt
4981 acgtgcccag acaagagcca atgttcagat ggatgagatt ctcagatctg agcacgtggg
5041 agggcgatcg caatctggct cccagttttg tgaatgaaga tggcgtcgag tgacgccaac
5101 ccatctgatg ggtccgcagc caacctcgtc ccagaggtca acaatgaggt tatggctctg
5161 gagcccgttg ttggtgccgc cattgcggca cctgtagcgg gccaacaaaa tgtaattgac
5221 ccctggatta gaaataattt tgtacaagcc cctggtggag agtttacagt gtcccccaga
5281 aacgctccag gtgaaatact atggagcgcg cccttaggcc ctgatttaaa tccctaccta
5341 tcccatttgg ctagaatgta taatggttat gcaggtggtt ttgaagtgca ggtaattctc
5401 gcggggaacg cgttcaccgc cgggaaggtc atatttgcag cagtcccacc aaatttccca
5461 actgaaggct tgagccccag ccaggtcact atgttccccc atatagtagt agatgttagg
5521 caattagaac ctgtgttgat tcccttaccc gatgttagga ataatttcta tcattataat
5581 caatcaaatg accccaccat taagttgata gcaatgttgt acacaccact tagggctaat
5641 aatgctgggg acgatgtctt cacagtttct tgccgagttc tcacgagacc atcccccgat
5701 tttgatttca tatttctagt accacctaca gttgagtcta gaactaaacc attctctgtc
5761 ccagttttaa ctgttgagga gatgaccaat tcaagattcc ccattcctct ggaaaagttg
5821 ttcacgggtc ccagcagtgc ctttgttgtt caaccacaaa acggtaggtg cacgactgat
5881 ggcgtgctcc taggcaccac ccaattgtct cctgtcaaca tctgcacctt cagaggggat
5941 gtcacccaca ttacaggtag tcgtaactac acaatgaatt tggcttctca aaattggaac
6001 aattatgacc caacagaaga aatcccagcc cctctaggag ctccagattt tgtggggaag
6061 attcaaggca tgctcaccca aaccacaagg gcagatggct caacacgcgg ccacaaagcc
6121 acggtgtaca ctgggagcgc cgactttgct ccaaaactgg gcagagttca atttgaaact
6181 gacacagacc atgattttga agctagccaa aacacaaagt tcaccccagt cggtgtcatc
6241 caagacggca gcaccaccca ccgaaatgaa ccccaacagt gggtgctccc aagttactca
6301 ggcagaaata ctcataatgt tcatctggcc cccgctgtag cccctacttt tccgggtgag
6361 caactcctct tctttaggtc cactatgccc ggatgtagcg ggtaccccaa catggatctg
6421 gactgtctgc tcccccagga atgggtgcag tacttctacc aagaggcagc cccagcgcaa
6481 tctgatgtgg ctctgctaag atttgtgaat ccagacacag gtagggtttt gtttgagtgt
6541 aaactccata aatcaggcta tgttacagtg gctcacactg gccaacatga tttggttatc
6601 ccccccaatg gttattttag gtttgattcc tgggtcaacc agttctacac gcttgccccc
6661 atgggaaatg gagcggggcg tagacgtgta gtataatggc tggagctttc tttgctgggt
6721 tagcatctga tgtccttggc tctggacttg gttcccttat caatgctggg gctggggcca
6781 tcaaccaaaa agttgagttt gaaaataaca gaaaattgca acaagcatcc ttccaattta
6841 gcagcaatct acaacaggct tcctttcaac atgacaaaga aatgctccaa gcacaaattg
6901 aggccaccaa aaagctacaa caggaaatga tgaaagttaa gcaggcaatg ctcctagagg
6961 gtgggttctc tgagacagat gcagcccgcg gggcaattaa cgcccccatg acaaaagctt
7021 tggactggag cgggacaagg tactgggctc ctgatgctag gactacaaca tacaatgcag
7081 gccgcttttc cacccctcaa ccatcggggg cactgccagg aagaactaat cttagggata
7141 ctgtccctgc tcggggttcc tctagtaaat cttttaactc ttctactgtt acttctgtgc
7201 actcaaatca aaccacttca acgagacttg gttctacagc tggttctggt accagtgtct
7261 cgagtctccc gtcaactgca aggactagga gctgggttga ggatcaaagt aggagtttgt
7321 ctcctttcat gaggggggcc cacaacatat cgtttgtcac cccaccatct agcagatcct
7381 ctagccaagg cacagtctca accgtgccta aagaggtttt ggactcctgg actggcgctt
7441 tcaacacgcg caggcagcct ctcttcgctc acattcgtaa acgaggggag tcacgggtgt
7501 aatgtgaaaa gacaaaattg attatctttc tttctcttta
//