Typing tool
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Typing tool
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Complete norovirus genomes
| MK775031 | GII.13 | |
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| GII.P16 |
ORF1: 1..5040
ORF2: 5021..6649
ORF3: 6649..7380
LOCUS MK775031 7397 bp RNA linear VRL 15-APR-2019
DEFINITION Norovirus GII isolate Hu/US/2017/GII.P16-GII.13/Butler0349
nonstructural polyprotein (ORF1) gene, partial cds; and VP1 (ORF2)
and VP2 (ORF3) genes, complete cds.
ACCESSION MK775031
VERSION MK775031.1
KEYWORDS .
SOURCE Norovirus GII
ORGANISM Norovirus GII
Viruses; Riboviria; Orthornavirae; Pisuviricota; Pisoniviricetes;
Picornavirales; Caliciviridae; Norovirus; Norwalk virus.
REFERENCE 1 (bases 1 to 7397)
AUTHORS Barclay,L., Cannon,J.L., Wikswo,M.E., Phillips,A., Browne,H.,
Montmayeur,A.M., Tatusov,R.L., Burke,R.M., Hall,A.J. and Vinje,J.
TITLE Emergence and characterization of multiple viruses associated with
a novel GII.P16 polymerase in the United States, 2015-2018
JOURNAL Unpublished
REFERENCE 2 (bases 1 to 7397)
AUTHORS Barclay,L., Cannon,J.L., Brandt,E., Montmayeur,A.M., Tatusov,R.L.,
Chhabra,P. and Vinje,J.
TITLE Direct Submission
JOURNAL Submitted (09-APR-2019) Division of Viral Diseases, Centers for
Disease Control and Prevention, 1600 Clifton Road NE, Atlanta, GA
30329, USA
COMMENT ##Assembly-Data-START##
Assembly Method :: Geneious v. R10; SPAdes v. 3.6
Sequencing Technology :: Illumina
##Assembly-Data-END##
FEATURES Location/Qualifiers
source 1..7397
/organism="Norovirus GII"
/mol_type="genomic RNA"
/strain="Butler0349"
/isolate="Hu/US/2017/GII.P16-GII.13/Butler0349"
/isolation_source="stool"
/host="Homo sapiens"
/db_xref="taxon:122929"
/country="USA"
/collection_date="02-Feb-2018"
/note="genotype: GII.P16-GII.13"
gene <1..5040
/gene="ORF1"
CDS <1..5040
/gene="ORF1"
/codon_start=1
/product="nonstructural polyprotein"
/protein_id="QBY35942.1"
/translation="KEKSSGEGLFTNMSSTLKKALGARPKQPAPRDNSQKPPRPPTPE
LVKRIPPPPPNGEEEEPVIRYEVKSGISGLPELTTVPQPDVANTAFSVPPLSLRENRE
AKEPLTGAILEMWDGEIYHYGLYVEKGLVLGVHKPPAAISMAKVELTPLSLYWRVVYT
PQYLISPETLRRLNGEAFPYTAFDNNCYAFCCWVLDLNDSWLNRRMVQRTTGFFRPYQ
EWNRKPLPTMDDSKIKKVANIFLCSLSTLFTRPIKDLIGKIKPLNILNILATCDWTFA
GIVESLILLAELFGVFWTPPDVSAMIAPLLGDYELQGPEDLAVELVPVVMGGIGLVLG
FTKEKIGKMLSSAASTLRACKDLGAYGLEILKLIMKWFFPKKEEANELAMVRAIEDAV
LDLEAIENNHMTTLLKDKDSLATYMKTLDMEEEKARRLSTKSASPDIVGTINALLARI
AAARSLVHRAKEELSSRIRPVVVMISGKPGIGKTHLAREVARKVASTLTGDQRVGLIP
RNGVDHWDAYKGERVVLWDDYGMSNPIHDALRIQELADTCPLTLNCDRIENKGKVFDS
EVIIITTNLANPAPLDYVNFEACSRRIDFLVYAEAPEVEKAKRDFPGQPDMWKDAFKS
DFSHIKLQLAPQGGFDKNGNTPHGKGVMKTLTTGSLIARASGLLHERMDEFELQGPTV
TTFNFDRNRIAAFRQLAAENKYGLVDTMRVGNQLKGVKTMEELKQAIRNVIIKRCRII
YGGSTYDLESDGKGRVLVEKVKNTSVQTNNELAGALHHLKHARIRYYVKCVQEAVYSI
IQIAGAAFVTTRIVRRMNIQELWSKPPLDQNESEAKEEAPKSEDDEFIISFKDIKEEG
KKGKNKTGRGKKHTAFSSKGLSDEEYDEYKRIREERNGKYSIEEYLQDRDRYYEELAI
AKATEEDFCEEEEIKIRQRIFRPTRKQRKEERVTLGLVTGSEIRKRNPDDFKPKGKLW
ADDNRSVDYNEKLDFEAPPSIWSRIVSFGSGWGFWVSPSLFITSTHVIPAGITEAFGV
PIKQIQVHKSGEFCRFRFPKPIRSDVTGMILEEGAPEGTVATVLIKRPTGELMPLAAR
MGTHATMKIQGRMVGGQMGMLLTGSNAKGMDLGTTPGDCGCPYIYKRGNDYIVIGVHT
AAARGGNTVICATQGSEGEATLEGGDDKGTYCGAPILGPGGAPKLSTKTKFWRSSNTP
LPPGTYEPAYLGGRDPRVKGGPSLQQVMRDQLKPFTEPRGKPPRPSVLEAAKQTIINV
LEQTLDPPQKWTYAQACASLDKTTSSGHPHHVRKNEFWNGETFTGKLADQASKANLMF
EEGKHMTPVYTAALKDELVKTDKVYGKIKKRLLWGSDLSTMIRCARSFGGLMDEMKAH
CISLPVRVGMNMNEDGPIIFEKHSRYKYHYDADYSRWDSTQQRAVLAAALEIMVRFSA
EPQLAQIVAEDLLAPSVVDVGDFKISINEGLPSGVPCTSQWNSIAHWLLTLCALSEVT
KLSPDIVQANSMFSFYGDDEIVSTDIKLDPEKLTTKLKEYGLKPTRPDKTEGPLIISE
DLNGLTFLRRTVTRDPAGWFGKLDQSSILRQMYWTRGPNHEDPNETMIPHSQRPIQLM
ALLGEASLHGPSFYSKISKLVITELKEGGMDFYVPRQEPMFRWMRFSDLSTWEGDRNL
APNFVNEDGVE"
mat_peptide <1..936
/gene="ORF1"
/product="p48"
mat_peptide 937..2034
/gene="ORF1"
/product="NTPase"
mat_peptide 2035..2565
/gene="ORF1"
/product="p22"
mat_peptide 2566..2964
/gene="ORF1"
/product="VPg"
mat_peptide 2965..3507
/gene="ORF1"
/product="Pro"
mat_peptide 3508..5037
/gene="ORF1"
/product="RdRp"
gene 5021..6649
/gene="ORF2"
CDS 5021..6649
/gene="ORF2"
/note="major capsid protein"
/codon_start=1
/product="VP1"
/protein_id="QBY35943.1"
/translation="MKMASNDAAPSNDGAASLVPEAINETMPLEPVAGASIAAPVAGQ
TNIIDPWIRTNFVQAPNGEFTVSPRNSPGEILLNLELGPDLNPYLAHLSRMYNGYAGG
VEVQVLLAGNAFTAGKILFAAIPPNFPVDMISPAQITMLPHLIVDVRTLEPIMIPLPD
VRNVFYHFNNQPQPRMRLVAMLYTPLRSNGSGDDVFTVSCRVLTRPTPDFEFIYLVPP
SVESKTKPFTLPILTISELTNSRFPIPIEQLYTAPNENNVVQCQNGRCTLDGELQGTT
QLLSSAICSYRGRTVANSGDNWDQNLLQLTYPSGASYDPTDEVPAPLGTQDFSGILYG
VLTQDNVSEGTGEAKNAKGVYISTTSGRFTPKIGTIGLHSITENVHPNQQSRFTPVGV
AQNENTPFQQWVLPHYAGALALNTNLAPAVAPTFPGEQLLFFRSRVPCVQGLRGQDAF
IDCLLPQEWVNHFYQEAAPSQADVALIRYVNPDTGRTLFEAKLHRSGFITVSHTGTYP
LVVPPNGHFRFDSWVNQFYSLAPMGTGNGRRRVQ"
gene 6649..7380
/gene="ORF3"
CDS 6649..7380
/gene="ORF3"
/note="minor structural protein; small basic protein"
/codon_start=1
/product="VP2"
/protein_id="QBY35944.1"
/translation="MAGAFIAGLAGDMLTSAVGSLTSAGANAINQKLNFDYNKQLQNA
SFQHDKEMLQAQIDATKKLQSEMIAIKHGVLTAGGFSPADAARGAVNAPMTRVLDWSG
TRYYAPNSVQTTSYSGQFTPSPVHRAQVKSPSNSSQRTAAPSSIRSLSTQSTSLGSTS
SGGSSITSSSSRTADWVQQQRALSPYMHGALQTAYVTPPSSRASSMSSVSTVPKGVLD
SWTPVFNTRRQPLFAHLRKRGESQA"
ORIGIN
1 aaggaaaaat cttcaggtga aggcttattc acaaatatgt cttccacctt aaagaaagcc
61 ctcggggccc ggcccaaaca gcctgccccg agggacaact cacaaaagcc cccaagacca
121 ccaactcccg agttggttaa gaggataccc cctcccccac ctaatggaga agaagaagaa
181 ccagtcatta ggtatgaggt taagagtgga atctctggcc tgcccgagct cacaacagtc
241 cctcaaccgg atgtggccaa cacggcattc agtgtcccac cgctgagctt gagagaaaac
301 agggaggcca aggaaccgct gacaggggca atattagaga tgtgggacgg agagatatac
361 cactatggcc tgtacgtgga gaaaggctta gtgttgggtg tgcacaaacc acctgcagct
421 ataagcatgg caaaagtgga gctgacgccg ttgtcattgt actggcgtgt ggtctacacc
481 ccccaatacc tcatctcccc tgaaactctc aggaggctca acggagaggc attcccttac
541 actgcctttg acaacaactg ctatgccttt tgctgctggg tattagacct caatgactca
601 tggcttaaca gaaggatggt gcaaagaaca acaggcttct tcagacctta ccaagagtgg
661 aacagaaaac ccctgcccac tatggatgac tccaaaatca agaaggtggc aaacatattc
721 ctgtgttcat tgtccacgtt gttcaccaga cctataaaag acctcatagg aaaaattaag
781 ccattgaaca tcttgaacat cctggcaacg tgtgactgga cattcgccgg aatagtggag
841 tctctgatat tacttgctga actctttgga gttttctgga cacccccaga tgtgtctgct
901 atgatcgctc ctttacttgg agactacgag ttgcaagggc cagaagacct tgccgttgag
961 ctcgtacctg tagtaatggg agggattggt ttggtgttgg gattcaccaa agagaaaatt
1021 ggaaaaatgt tgtcctcagc agcatcaacg ctcagggctt gtaaagatct tggtgcctat
1081 ggcttagaga tactcaaatt gatcatgaag tggttcttcc caaagaaaga agaggccaat
1141 gagctagcca tggtgagagc tatagaggat gctgtactgg atcttgaggc aatagaaaat
1201 aatcacatga caactctgtt gaaagacaaa gacagcctag caacctacat gaaaacacta
1261 gacatggagg aggaaaaagc cagaaggttg tccacaaaat ctgcatcccc tgacatagtt
1321 gggacgatca acgccctgct ggctcgtata gcagcggcta ggtcactagt ccacagggcc
1381 aaggaggagt tatctagcag gataagacca gtggttgtta tgatatctgg caaaccaggg
1441 ataggcaaaa ctcatttggc cagggaggtg gcaagaaagg tggcatccac tctcacaggg
1501 gatcaaagag tcgggctcat accgaggaac ggtgtggacc attgggacgc atacaaaggt
1561 gagagagtcg tgttgtggga cgactatggc atgagcaacc ccattcatga tgctctgcgc
1621 atacaagaat tggctgatac gtgccccctt accttaaatt gtgacagaat tgaaaataag
1681 ggaaaagttt ttgacagtga agtcataata atcacaacaa accttgccaa tccggctcca
1741 cttgactatg tcaactttga ggcctgttcc aggagaattg acttcctggt gtacgccgag
1801 gcaccagaag tagaaaaggc aaaacgagac tttcctggac aaccagatat gtggaaggac
1861 gccttcaagt cggacttttc acacatcaag ttgcaacttg cgcctcaggg cggttttgac
1921 aagaatggca acaccccaca tgggaaagga gtgatgaaga ccctcaccac cggttccctg
1981 atcgcccgtg catcaggctt actgcatgag aggatggatg aatttgaact ccaaggcccc
2041 acagtcacca ccttcaattt tgaccggaac agaatcgctg cattcagaca attggctgca
2101 gaaaacaagt atggattggt ggacaccatg agagttggca atcaattaaa aggggtgaaa
2161 actatggaag aactcaaaca agcaatcagg aatgtgatca tcaagaggtg ccggatcatc
2221 tacggcggct ccacgtatga ccttgaatct gatggcaagg gcagagtttt ggtggaaaag
2281 gtcaagaaca cctctgtgca gaccaacaac gagttggccg gagccctgca tcacctcaaa
2341 catgcccgaa tcaggtacta tgtcaaatgt gtgcaagaag cagtctactc tattatacaa
2401 atcgccggcg ctgcgtttgt caccacacgc atagtacgcc gcatgaacat acaagagctt
2461 tggtcgaagc caccattaga tcaaaatgaa tcagaggcta aggaagaggc ccccaagtca
2521 gaagatgacg agttcatcat atcttttaag gacatcaagg aggaaggaaa gaagggcaaa
2581 aacaaaactg gccgtggtaa gaaacatact gcattctcta gcaagggctt gagcgatgag
2641 gagtatgacg agtacaagag gataagagaa gagagaaatg ggaagtactc tatagaggag
2701 tatcttcaag acagagacag gtactatgag gaactcgcca tcgccaaggc cacggaagaa
2761 gacttctgtg aggaggagga gatcaaaatc cgtcagagga tcttccgtcc caccaggaag
2821 caaaggaagg aagagagggt cacactaggg ctagtaactg gttcagaaat cagaaaaaga
2881 aaccctgatg acttcaaacc taaagggaaa ctgtgggctg atgacaacag aagtgttgac
2941 tacaatgaga aactggactt tgaggccccc ccaagtatat ggtctaggat tgtgagtttt
3001 ggttctggtt ggggcttctg ggtgtcacca agcctgttca taacatcaac tcatgtaatc
3061 cctgcaggca taacagaagc gtttggagtc cccatcaaac aaatccaggt ccacaaatca
3121 ggtgaatttt gccggttcag attcccaaaa ccaattagat cagatgtgac aggaatgatc
3181 ttggaagaag gtgcgcctga gggcaccgtg gcaaccgtgc tcatcaaacg ccctaccgga
3241 gagctcatgc cccttgcagc cagaatggga acacacgcga ccatgaaaat tcagggccgc
3301 atggttggcg gacagatggg tatgttgctc actggttcaa acgctaaagg aatggatttg
3361 ggaacaactc ctggtgattg tggctgtccc tacatctaca aaaggggcaa tgactatata
3421 gtcattgggg tgcacacagc agcagcccgt ggtggaaaca ccgtcatctg tgccacacag
3481 ggaagtgagg gtgaggcaac tcttgagggt ggagatgaca aaggaacata ctgtggggca
3541 cccattctag gccctggggg ggcaccaaaa ctgagcacca aaaccaaatt ttggaggtca
3601 tcgaacacgc ctcttccacc aggaacgtat gagcctgcct acctcggtgg ccgtgacccg
3661 cgtgttaagg gtgggccctc cttgcagcag gtaatgagag accagttgaa gccattcacc
3721 gagcccaggg gtaaacctcc aagaccaagt gtgttggaag cagccaaaca aaccatcatc
3781 aacgtcctcg aacaaaccct ggaccctcca caaaaatgga catacgcaca ggcgtgtgct
3841 tcacttgaca aaaccacctc cagcgggcat ccccaccacg tccgaaagaa tgaattctgg
3901 aatggtgaga ccttcactgg taaattggca gaccaagcat caaaagcaaa tctaatgttt
3961 gaggaaggga aacacatgac accagtgtat acagcagccc tcaaggatga actggtcaag
4021 actgataaag tctatggaaa gatcaagaaa agactgctct ggggctctga cttgtccacc
4081 atgatccggt gcgccaggtc ctttggtggg ctcatggatg agatgaaagc acactgcata
4141 tcactcccag ttcgagttgg catgaacatg aatgaagatg gtccaataat atttgagaag
4201 cactccagat ataagtatca ctatgatgca gattactccc gctgggattc aacacaacag
4261 agggcagtgc tagcagcagc cttggagatc atggtcaggt tctctgcaga gccacaattg
4321 gcacaaatag tcgctgagga tctgctggcc cccagtgtgg tagacgtagg agactttaaa
4381 atttcaataa atgaagggct cccctctggt gtaccatgca cttctcaatg gaattccatc
4441 gcacactggc tgctaaccct ctgcgccttg tctgaagtca ccaaactgtc ccctgacatt
4501 gtacaggcaa attctatgtt ctcattttac ggtgatgacg agattgtcag caccgatata
4561 aaattggacc ctgaaaagtt aaccaccaaa ttgaaggagt acggcctgaa accaactcgc
4621 ccagacaaaa ccgagggacc cctgatcatc agtgaggatc tgaacggact tactttcctc
4681 cggaggacgg tgactcgtga cccagctggc tggtttggaa aattggacca aagctcaata
4741 ctgaggcaga tgtactggac tagaggacca aatcatgaag accccaatga gacaatgata
4801 ccccactctc aaagacccat acagctcatg gcactgcttg gtgaggcctc ccttcacgga
4861 ccctctttct acagcaaaat tagtaagttg gtcataactg aactcaaaga aggtgggatg
4921 gacttttacg tgccaaggca ggaacccatg ttcaggtgga tgaggttctc tgacttgagc
4981 acgtgggagg gcgatcgcaa tctggctccc aattttgtga atgaagatgg cgtcgaatga
5041 cgccgctcca tcgaatgatg gtgcagctag tctcgtacca gaggccatta atgagactat
5101 gccattggaa cccgttgctg gcgcatctat tgctgcccca gtggcgggac aaactaacat
5161 aattgacccc tggataagaa caaattttgt gcaagcccct aatggagagt tcacagtatc
5221 accgagaaat tcccctggag agattttatt aaatttagag ttaggaccag atttgaatcc
5281 ttatttggcc catctatcaa ggatgtacaa tggatatgct ggaggtgttg aggtgcaagt
5341 gcttcttgct gggaacgcgt tcacagcggg aaagatattg tttgcagcaa tcccacccaa
5401 ctttcctgta gatatgatta gcccagctca aattactatg cttccccatt tgattgtaga
5461 tgttaggaca ttggaaccta ttatgatacc cttacctgat gttaggaatg tgttctatca
5521 ttttaataat caaccccaac ctaggatgag attagtggct atgctttata ccccattgag
5581 atctaatggt tcaggagatg atgtttttac tgtgtcttgt agagtgttga ctaggccaac
5641 ccctgatttt gaattcattt acctagtgcc tccctctgta gagtccaaaa ctaaaccatt
5701 cacacttcca atattgacca tttctgaact aaccaactcc cggtttccca tcccaattga
5761 gcaactgtac acggccccaa atgagaataa tgttgtacag tgtcaaaatg gaaggtgcac
5821 cttggatgga gagcttcagg gcaccaccca gctgctatca agtgcaattt gctcttacag
5881 gggcaggact gtggctaaca gtggggacaa ttgggaccag aatttgctcc agctgaccta
5941 cccaagcggt gcaagctatg accccactga tgaagtacca gcacccttgg gcacccaaga
6001 tttcagtggg atattgtatg gggtgttaac ccaagacaat gtaagtgagg gtacagggga
6061 ggccaaaaat gctaagggag tatacatatc caccaccagt ggaagattca ccccaaaaat
6121 tgggacaatt ggattgcatt caataactga aaatgtgcac cccaatcagc aatcacggtt
6181 cacccccgta ggagtcgctc agaatgaaaa cacccccttc cagcaatggg ttctaccaca
6241 ctacgcaggt gctctcgctc taaacaccaa tttggcaccc gctgttgccc cgaccttccc
6301 tggtgagcaa ttactgttct tcaggtcccg tgttccatgt gttcaaggtc tgcgggggca
6361 ggatgctttc atagattgtc tcctacctca agagtgggtg aaccattttt atcaagaggc
6421 tgctccctcc caagcagacg ttgccctcat caggtacgtc aaccctgata ctggtcgcac
6481 gctgtttgag gccaaattgc acaggtcagg tttcattact gtatcacaca ctggcactta
6541 ccctcttgtg gttcccccga atggtcattt caggtttgat tcttgggtta accaattcta
6601 ctcactcgcc cccatgggaa ctggcaatgg gcgtagaaga gttcaataat ggcaggagca
6661 tttatagctg gtctagccgg tgacatgctg acttctgctg ttggttcact gacctctgca
6721 ggagccaatg ccatcaatca gaaattgaat tttgattaca ataaacaact ccaaaatgca
6781 tcctttcaac atgataagga aatgttgcag gcccaaattg atgctacaaa gaagctccaa
6841 tcagaaatga ttgcaattaa gcatggggtt ttgaccgcag gcggcttctc cccagctgat
6901 gcagccagag gggcagtcaa cgccccaatg actcgagtgt tggattggtc agggacacgc
6961 tactacgctc caaattctgt gcaaaccacc agttattctg ggcaattcac cccctcgcca
7021 gtccatcggg cgcaggtgaa gtccccttcc aattcatctc agcggactgc agctccaagc
7081 agtatccgca gcctgtcaac ccaatcaact tctttaggct ccacctcctc aggggggtcc
7141 tctataacct cctctagttc gaggacagca gactgggtgc aacaacaaag ggctcttagc
7201 ccgtacatgc atggagccct gcaaacggca tatgtcacac cgccgtctag tagggcttcc
7261 agtatgagct ctgtctcaac agtgcccaaa ggggttttgg actcctggac acctgtgttc
7321 aacacacgca ggcagccgct gtttgcacac ctcaggaaga ggggggagtc acaggcttag
7381 tgaaaaggat aatcaac
//