Typing tool
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Typing tool
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Complete norovirus genomes
| MK775030 | GII.2 | |
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| GII.P16 |
ORF1: 1..5099
ORF2: 5080..6708
ORF3: 6708..7479
LOCUS MK775030 7479 bp RNA linear VRL 15-APR-2019
DEFINITION Norovirus GII isolate Hu/US/2017/GII.P16-GII.2/Lake0345
nonstructural polyprotein (ORF1) gene, partial cds; VP1 (ORF2)
gene, complete cds; and VP2 (ORF3) gene, partial cds.
ACCESSION MK775030
VERSION MK775030.1
KEYWORDS .
SOURCE Norovirus GII
ORGANISM Norovirus GII
Viruses; Riboviria; Orthornavirae; Pisuviricota; Pisoniviricetes;
Picornavirales; Caliciviridae; Norovirus; Norwalk virus.
REFERENCE 1 (bases 1 to 7479)
AUTHORS Barclay,L., Cannon,J.L., Wikswo,M.E., Phillips,A., Browne,H.,
Montmayeur,A.M., Tatusov,R.L., Burke,R.M., Hall,A.J. and Vinje,J.
TITLE Emergence and characterization of multiple viruses associated with
a novel GII.P16 polymerase in the United States, 2015-2018
JOURNAL Unpublished
REFERENCE 2 (bases 1 to 7479)
AUTHORS Barclay,L., Cannon,J.L., Brandt,E., Montmayeur,A.M., Tatusov,R.L.,
Chhabra,P. and Vinje,J.
TITLE Direct Submission
JOURNAL Submitted (09-APR-2019) Division of Viral Diseases, Centers for
Disease Control and Prevention, 1600 Clifton Road NE, Atlanta, GA
30329, USA
COMMENT ##Assembly-Data-START##
Assembly Method :: Geneious v. R10; SPAdes v. 3.6
Sequencing Technology :: Illumina
##Assembly-Data-END##
FEATURES Location/Qualifiers
source 1..7479
/organism="Norovirus GII"
/mol_type="genomic RNA"
/strain="Lake0345"
/isolate="Hu/US/2017/GII.P16-GII.2/Lake0345"
/isolation_source="stool"
/host="Homo sapiens"
/db_xref="taxon:122929"
/country="USA"
/collection_date="20-Aug-2017"
/note="genotype: GII.P16-GII.2"
gene <1..5099
/gene="ORF1"
CDS <1..5099
/gene="ORF1"
/codon_start=3
/product="nonstructural polyprotein"
/protein_id="QBY35939.1"
/translation="NMASNDATVAVACNNNNDKEKSSGEGLFTNMSSTLKKALGARPK
QPAPRDKPQKPPRPPTPELVKRIPPPPPNGEEEEEPVIRYEVKSGISGLPELITVPQP
DVANTAFSVPPLSLRENREAKEPLTGAILEMWDGEIYHYGLYVEKGLVLGVHKPPAAV
SMARVELTPLSLYWRVVYTPQYLISPETLRRLNGEAFPYTAFDNNCYAFCCWVLDLND
SWLSRRMVQRTTGFFRPYQEWNRKPLPTMDDSKIKKVANIFLCSLSTLFTRPIKDLIG
KIKPLNILNILATCDWTFAGIVESLILLAELFGVFWTPPDVSAMIAPLLGDYELQGPE
DLAVELVPVVMGGIGLVLGFTKEKVGKMLSSAASTLRACKDLGAYGLEILKLVMKWFF
PKKEEANELAMVRAIEDAVLDLEAIENNHMTTLLKDKDSLATYMKTLDMEEEKARRLS
TKSASPDIVGTINALLARIAAARSLVHRAKEELSSRIRPVVVMISGKPGIGKTHLARE
VARKVASTLTGDQRVGLIPRNGVDHWDAYKGERVVLWDDYGMSNPIHDALRIQELADT
CPLTLNCDRIENKGKVFDSEVIIITTNLANPAPLDYVNFEACSRRIDFLVYADAPEVE
KAKRDFPGQPDMWKDAFKSDFSHIKLQLAPQGGFDKNGNTPHGKGVMKTLTTGSLIAR
ASGLLHERMDEFELQGPTITTFNFDRNRITAFRQLAAENKYGLVDTMRVGNQLKGVKT
MEELKQAIRNVTIKRCRIIYGGSTYDLESDGKGKVLVEKVKNTSVQTNNELAGALHHL
KHARIRYYVKCVQEAVYSIIQIAGAAFVTTRIARRMNIQELWSKPQLGQNESETKEEA
PKSGDDEFIISSKDIKEEGKKGKNKTGRGKKHTAFSSKGLSDEEYDEYKRIREERNGK
YSIEEYLQDRDRYYEELAIAKATEEDFCEEEEIKIRQRIFRPTRKQRKEERATLGLVT
GSEIRKRNPDDFKPKGKLWADDNRSVDYNEKLDFEAPPSIWSRIVSFGSGWGFWVSPS
LFITSTHVIPAGITEAFGVPIKQIQIHKSGEFCRFRFPKPIRPDVTGMILEEGAPEGT
VATVLIKRPTGELMPLAARMGTHATMKIQGRMVGGQMGMLLTGSNAKGMDLGTTPGDC
GCPYIYKRGNDYIVIGVHTAAARGGNTVICATQGSEGEATLEGGDDKGTYCGAPILGP
GGAPKLSTKTKFWRSSNTPLPPGTYEPAYLGGRDPRVKGGPSLQQVMRDQLKPFTEPR
GKPPRPSVLEAAKQTIINVLEQTLDPPQKWTYAQACASLDKTTSSGHPYHVRKNEFWN
GETFTGKLADQASKANLMFEEGKHMTPVYTAALKDELVKTEKIYGKIKKRLLWGSDLS
TMIRCARSFGGLMDEMKAHCISLPVRVGMNMNEDGPIIFEKHSRYKYHYDADYSRWDS
TQQRAVLAAALEIMVRFSAEPQLAQIVAEDLLAPSVVDVGDFKITINEGLPSGVPCTS
QWNSIAHWLLTLCALSEVTKLSPDIIQANSLFSFYGDDEIVSTDIKLDPEQLTAKLKE
YGLKPTRPDKTEGPLIISEDLNGLTFLRRTVTRDPAGWFGKLDQSSILRQMYWTRGPN
HEDPNETMIPHSQRPIQLMALLGEASLHGPSFYSKISKLVITELKEGGMDFYVPRQEP
MFRWMRFSDLSTWEGDRNLAPNFVNEDGVE"
mat_peptide <1..995
/gene="ORF1"
/product="p48"
mat_peptide 996..2093
/gene="ORF1"
/product="NTPase"
mat_peptide 2094..2624
/gene="ORF1"
/product="p22"
mat_peptide 2625..3023
/gene="ORF1"
/product="VPg"
mat_peptide 3024..3566
/gene="ORF1"
/product="Pro"
mat_peptide 3567..5096
/gene="ORF1"
/product="RdRp"
gene 5080..6708
/gene="ORF2"
CDS 5080..6708
/gene="ORF2"
/note="major capsid protein"
/codon_start=1
/product="VP1"
/protein_id="QBY35940.1"
/translation="MKMASNDAAPSTDGAAGLVPESNNEVMALEPVAGVALAAPVTGQ
TNIIDPWIRANFVQAPNGEFTVSPRNAPGEVLLNLELGPELNPYLAHLARMYNGYAGG
MEVQVMLAGNAFTAGKLVFAAVPPHFPVENLSPQQITMFPHVIIDVRTLEPVLLPLPD
VRNSFFHYNQKDDPKMRIVAMLYTPLRSNGSGDDVFTVSCRVLTRPSPDFDFTYLVPP
TVESKTKLFTLPILTLGELSNSRFPVSIDQMYTSPNEVISVQCQNGRCTLDGELQGTT
QLQVSGICAFKGEVTAHLHDNDHLYNVTITNLNGSPFDPSEDTPAPLGVPDFQGRVFG
IISQRDKHNSPGHNEPANRGHDAVVPTYTAQYTPKLGQIQIGTWQTDDLTVNQPVKFT
PVGLNDTEHFNQWVVPKYAGALNLNTNLAPSVAPVFPGERLLFFRSYIPLKGGYGNPA
IDCLLPQEWVQHFYQEAAPSMSEVALVRYINPDTGRALFEAKLHRAGFMTVSSNTSAP
VVVPANGYFRFDSWVNQFYSLAPMGTGNGRRRVQ"
gene 6708..>7479
/gene="ORF3"
CDS 6708..>7479
/gene="ORF3"
/note="minor structural protein; small basic protein"
/codon_start=1
/product="VP2"
/protein_id="QBY35941.1"
/translation="MAGAFVAGLAGDVLSNGLSSLINAGANAINQRAEFDFNQKLQQN
SFNHDKEMLQAQIQATKQLQADMMAIKQGVLTAGGFSPADAARGAVNAPMTQALDWNG
TRYWAPNSMRTTSYSGKFTSTAPVRQADFQHTQSRSSSGSSVSSFATQSSRPTLTTTT
GSSHGTVSSNSTRSTSLSQSTVSRATSRTGEWVRDQNRNLEPYMHGALQTAFVTPPSS
RASDGTVSTVPKGVLDSWTPAFNTRRQPLFAHLRKRGES"
ORIGIN
1 ggaatatggc gtctaacgac gctaccgttg ccgttgcttg caacaacaac aacgacaaag
61 aaaaatcttc aggtgaaggc ttattcacaa atatgtcttc caccttaaag aaagccctcg
121 gggctaggcc caaacagcct gccccgagag acaaaccaca aaagccccca agaccaccaa
181 ctcccgagtt ggtcaagagg ataccccctc ctccacctaa tggcgaagaa gaagaagaac
241 cagtcattag gtatgaggtt aagagtggga tctctggcct gcccgagctc ataacagtcc
301 cccaaccgga cgtggccaac acagcattca gtgttccacc actgagcttg agagaaaaca
361 gggaggccaa ggaaccgtta acaggggcaa tattagagat gtgggatgga gagatatacc
421 actatggcct gtacgtggag aaaggcttag tgttgggtgt gcacaaacca cctgcagccg
481 taagcatggc aagagtggag ctgacgccgc tgtcattgta ctggcgtgtg gtgtacactc
541 cccaatacct catctcccct gaaactctca ggagactcaa cggagaggca ttcccttaca
601 ccgcctttga taataactgc tatgcctttt gctgctgggt gttagacctc aatgactcat
661 ggcttagcag gaggatggtg caaagaacaa cgggcttctt cagaccttat caagagtgga
721 acagaaaacc cctgcccacc atggatgact ccaaaattaa gaaggtagca aatatattcc
781 tatgttcatt gtccacatta ttcaccagac ccataaaaga cctcatagga aaaattaaac
841 cattaaacat attaaatatc ctggcaacgt gtgactggac ttttgccgga atagtggagt
901 ctctgatatt acttgctgaa ctcttcggag ttttctggac acccccagat gtgtctgcta
961 tgatcgctcc cttactcggg gactacgagt tgcaggggcc agaagacctc gccgttgagc
1021 tcgtgcctgt ggtaatgggg gggattggtt tggtgttggg attcaccaaa gagaaagttg
1081 gcaaaatgtt gtcctcagca gcatcaacac tcagggcttg caaagatctt ggtgcctatg
1141 gcttagagat actcaaactg gtcatgaagt ggttcttccc aaagaaagag gaggccaatg
1201 agttagccat ggtgagggcc atagaggatg ctgtactaga tcttgaggca atagaaaata
1261 accacatgac aaccctgttg aaagacaaag acagcttggc aacatacatg aaaacactgg
1321 acatggagga ggagaaagcc aggaggttgt ccacaaaatc tgcatcccct gacatagttg
1381 ggacaatcaa cgccctgctg gctcgaatag cagcggccag gtcattagtc cacagggcca
1441 aggaagagct atctagcagg ataagaccag tagttgtcat gatatctggc aaaccaggaa
1501 taggcaaaac tcatctggcc agggaggtgg caagaaaggt ggcgtccact ctcacagggg
1561 atcaaagagt cggactcata ccaagaaacg gtgtggacca ttgggatgca tacaaaggtg
1621 agagggtcgt gctgtgggac gactatggca tgagtaaccc catacatgat gctcttcgca
1681 tacaagaatt ggctgatacg tgtcccctta ccttaaattg tgacagaatt gaaaacaagg
1741 gaaaagtttt tgacagtgag gtcataataa ttacaacaaa ccttgccaat ccagccccac
1801 ttgattatgt taattttgag gcctgttcca ggagaattga tttcctggtg tacgctgatg
1861 caccagaagt agaaaaggca aaacgggact ttcctggtca gccagatatg tggaaggacg
1921 ccttcaagtc ggacttttca cacatcaagc tacagcttgc accccagggc ggctttgaca
1981 agaatggcaa caccccacat gggaaaggag tgatgaagac cctcactacc ggttctctga
2041 ttgcccgtgc atcaggccta ctgcatgaga ggatggatga atttgaactc caaggtccca
2101 caatcaccac cttcaatttc gaccggaaca gaatcacagc attcagacaa ttggctgcag
2161 aaaacaagta tggattggtg gataccatga gagttggcaa tcaactaaaa ggagtgaaaa
2221 ccatggagga actcaaacaa gcaatcagga atgtgaccat caagaggtgc cggatcatct
2281 acggtggctc cacgtatgac cttgaatctg atggcaaggg caaagttttg gtggaaaagg
2341 tcaagaacac ctctgtacag accaacaacg agttggctgg ggccctgcac catctcaaac
2401 acgcccgaat caggtactat gtcaaatgtg tgcaagaagc agtctattcc atcatacaaa
2461 ttgccggcgc tgcgtttgtc accacgcgca ttgcacgccg catgaacata caagaactct
2521 ggtcgaagcc acaattaggt caaaatgaat cagagactaa ggaagaggcc cccaagtcag
2581 gagatgacga gttcatcata tcttctaagg acatcaagga ggaaggaaag aagggcaaaa
2641 acaaaactgg tcgtggcaag aaacacactg cattctccag caagggcttg agcgatgagg
2701 agtacgacga gtacaagagg ataagagaag agagaaatgg gaagtactcc atagaggagt
2761 atcttcaaga cagagacagg tactatgagg agctcgccat tgccaaggcc acggaagaag
2821 acttctgtga agaggaggag atcaaaatcc gtcagagaat tttccgtccc accaggaaac
2881 aaagaaagga agagagggcc acattagggc tagtaacagg ttcagaaatc agaaaaagaa
2941 accctgatga tttcaaaccc aaagggaagc tgtgggccga tgacaacagg agtgttgact
3001 acaatgagaa attggacttt gaggcccccc caagcatatg gtctaggatt gtgagctttg
3061 gttctggctg gggcttctgg gtgtcaccaa gccttttcat aacgtcaact catgtaatcc
3121 ccgcaggcat aacagaagca tttggagtcc ccatcaaaca aattcagatc cacaaatcag
3181 gtgaattttg ccgattcaga ttcccaaaac caattagacc agatgtgaca gggatgatct
3241 tggaagaagg tgcgcctgag ggcaccgtgg caactgtgct catcaaacgc cccaccggag
3301 agctcatgcc tcttgcagcc agaatgggaa cacacgcaac catgaaaatt caaggccgca
3361 tggttggcgg acagatgggt atgttgctca ctggatcaaa tgctaaagga atggatttgg
3421 gaacaactcc tggtgactgt ggctgtcctt acatctataa aaggggcaat gactatatag
3481 tcattggggt gcacactgca gcagcccgtg gtggaaacac cgtcatctgt gccacacagg
3541 gaagtgaggg tgaggcaact cttgagggtg gagatgacaa aggaacatac tgtggggcac
3601 ccattctagg ccctgggggt gcaccaaaat tgagcaccaa aaccaaattt tggaggtcat
3661 cgaacacgcc ccttccacca gggacatatg aacctgccta cctcggtggc cgtgatccgc
3721 gtgttaaggg tgggccctcc ctgcagcagg taatgagaga ccagttgaag ccattcactg
3781 aacccagggg caaacctcca agaccaagtg tattggaagc agccaaacag accatcatca
3841 atgtcctcga acaaaccctg gaccctccac aaaaatggac atacgcacag gcgtgtgcct
3901 cacttgacaa aaccacctcc agcgggcatc cctatcacgt ccgaaagaat gaattctgga
3961 atggtgagac cttcactggt aaattggcag accaagcatc aaaagcaaac ctaatgtttg
4021 aggaagggaa acacatgaca ccagtgtaca cagcagcact caaggacgaa ctagtcaaga
4081 ctgagaaaat ctatggaaag atcaagaaga gactgctctg gggctctgac ttgtccacca
4141 tgatccggtg cgctaggtca tttggtgggc tcatggacga gatgaaggca cactgcatat
4201 cactcccagt ccgagttggc atgaatatga atgaagatgg cccaataata tttgagaaac
4261 actccagata caaatatcac tatgatgcag actactctcg ttgggattca acacaacaga
4321 gggcagtact agcagcagcc ttggaaatta tggtcagatt ctctgcagaa ccacaattgg
4381 cacaaatagt cgctgaggat ctgctggccc ctagtgtagt agatgtagga gactttaaaa
4441 ttacaataaa tgaagggctc ccctctggtg tgccatgcac ttctcaatgg aactccatcg
4501 cacactggct gctaactctc tgtgccttgt ctgaagtcac caaactgtcc cctgacatta
4561 tacaggcaaa ctccttgttc tcattttacg gtgatgacga gattgtcagc accgacataa
4621 aattggaccc tgaacagtta accgccaaat tgaaggagta cggcctgaaa ccaacccgcc
4681 cagacaaaac cgagggaccc ctgattatca gtgaagattt gaacggactc actttcctcc
4741 gaaggacagt gactcgtgac ccagctggct ggtttggaaa actggaccaa agctcaattt
4801 tgaggcagat gtactggact agaggaccaa atcatgaaga ccccaatgag acaatgatac
4861 cccattctca aagacccata cagctcatgg cactgcttgg tgaagcctct cttcacggac
4921 cctctttcta cagtaaaatc agtaaattgg tgataactga actcaaagaa ggtgggatgg
4981 acttttacgt gccaaggcag gagcccatgt tcaggtggat gaggttttct gacttgagca
5041 cgtgggaggg cgatcgcaat ctggctccca attttgtgaa tgaagatggc gtcgaatgac
5101 gccgctccat ctactgatgg tgcagccggc ctcgtgccag aaagtaacaa tgaggtcatg
5161 gctcttgaac ccgtggctgg tgtcgccttg gcagccccgg tcactggtca aacaaatatt
5221 atagaccctt ggattagagc aaattttgtc caggccccca atggtgaatt tacagtctct
5281 ccccgtaatg cccctggtga agtgctactg aatctagagt tgggtccaga attaaatcct
5341 tatctggcac atttagcaag aatgtacaat gggtatgccg gtgggatgga ggtgcaggtc
5401 atgttggctg ggaacgcgtt cacagccggc aagttggtct tcgccgccgt gccacctcac
5461 ttcccagttg aaaaccttag cccacagcaa atcaccatgt tccctcatgt gatcatagat
5521 gtgagaacct tggaacctgt tctgttacca ctccctgatg ttaggaatag tttcttccat
5581 tataatcaga aagatgatcc caagatgaga attgtggcta tgctttatac ccccctcagg
5641 tctaatggtt caggtgatga tgtgtttaca gtctcctgca gagtgttgac tagaccttcc
5701 cctgactttg acttcacata cctggtgcca ccaacagtgg agtctaaaac aaaactattc
5761 accctcccaa tcctcacact tggggaactt tctaattcca ggttcccagt gtccatagac
5821 cagatgtata ccagccctaa tgaagttata tcagtgcagt gtcaaaatgg taggtgcaca
5881 ctggacgggg agctccaggg gacaacacaa ctccaagtca gtggcatttg tgctttcaaa
5941 ggtgaagtga ccgcccactt gcatgacaat gatcatctat acaatgtcac catcacaaac
6001 ttgaatgggt ccccttttga tccctccgag gacacccctg cccctctggg tgtgcctgac
6061 ttccagggaa gggtttttgg tattatctcc caaagggaca aacacaatag tcctgggcat
6121 aatgaaccag caaacagggg acacgacgct gtggttccca cttacacagc acagtacact
6181 ccaaaactgg gacaaattca aattggcaca tggcagactg acgaccttac agtcaaccaa
6241 ccagtcaaat tcaccccagt tggactcaat gacactgaac attttaacca atgggtggtc
6301 cccaagtatg ctggtgccct aaaccttaat acaaaccttg ccccttctgt tgctccagta
6361 tttccaggag agcgcctgct cttcttcaga tcatacattc ccctcaaggg cggttatgga
6421 aacccagcca ttgattgcct actaccacaa gagtgggtgc aacacttcta tcaggaagca
6481 gccccttcaa tgagtgaggt agccctcgtc agatacatca acccggacac tggtcgggca
6541 ctgtttgagg ccaagctcca cagagctggt ttcatgacag tctcgagcaa caccagtgcc
6601 ccggtggttg tgcctgccaa cggatacttc agatttgatt cttgggtgaa ccaattctat
6661 tctctcgccc ccatgggaac tgggaatggg cgtagaaggg ttcaataatg gctggagctt
6721 ttgtagctgg tcttgcaggg gacgtgctca gtaatgggct tagttcattg atcaatgcag
6781 gtgctaatgc aataaatcag agggcagaat ttgattttaa tcagaaattg cagcaaaatt
6841 cttttaatca tgataaggag atgttgcagg ctcagattca ggcaactaag cagctgcagg
6901 cagacatgat ggctataaaa caaggggtct tgaccgctgg tggcttttcc cctgctgatg
6961 cagccagagg tgctgtgaac gcgcccatga cacaagcgct ggattggaat ggtacaaggt
7021 attgggcacc aaactccatg aggaccacat cttattctgg aaaattcaca tcaaccgccc
7081 cagtgaggca ggccgacttc cagcacaccc aaagccggtc ttcgagtggc tcctctgtgt
7141 cttcctttgc cactcagtct tcaaggccaa ctctgaccac aaccactggt tcctcacatg
7201 gcacagtttc atcaaattca actcgcagca caagcctctc ccaatcaacg gtctccagag
7261 ctacatctag gactggtgag tgggttagag atcaaaatag aaatttggaa ccctacatgc
7321 atggtgcctt acagacagcc tttgtcaccc caccttccag cagggcatct gacgggacag
7381 tctcaaccgt cccgaaaggt gttttggact cctggacacc tgcgtttaac acccgcaggc
7441 agccgctttt tgcacacctc cgtaagaggg gggagtcac
//