Typing tool
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Typing tool
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Complete norovirus genomes
| MK775029 | GII.2 | |
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| GII.P2 |
ORF1: 4..5103
ORF2: 5084..6712
ORF3: 6712..7491
LOCUS MK775029 7503 bp RNA linear VRL 15-APR-2019
DEFINITION Norovirus GII isolate Hu/US/2016/GII.P2-GII.2/Richland0514
nonstructural polyprotein (ORF1), VP1 (ORF2), and VP2 (ORF3) genes,
complete cds.
ACCESSION MK775029
VERSION MK775029.1
KEYWORDS .
SOURCE Norovirus GII
ORGANISM Norovirus GII
Viruses; Riboviria; Orthornavirae; Pisuviricota; Pisoniviricetes;
Picornavirales; Caliciviridae; Norovirus; Norwalk virus.
REFERENCE 1 (bases 1 to 7503)
AUTHORS Barclay,L., Cannon,J.L., Wikswo,M.E., Phillips,A., Browne,H.,
Montmayeur,A.M., Tatusov,R.L., Burke,R.M., Hall,A.J. and Vinje,J.
TITLE Emergence and characterization of multiple viruses associated with
a novel GII.P16 polymerase in the United States, 2015-2018
JOURNAL Unpublished
REFERENCE 2 (bases 1 to 7503)
AUTHORS Barclay,L., Cannon,J.L., Brandt,E., Montmayeur,A.M., Tatusov,R.L.,
Chhabra,P. and Vinje,J.
TITLE Direct Submission
JOURNAL Submitted (09-APR-2019) Division of Viral Diseases, Centers for
Disease Control and Prevention, 1600 Clifton Road NE, Atlanta, GA
30329, USA
COMMENT ##Assembly-Data-START##
Assembly Method :: Geneious v. R10; SPAdes v. 3.6
Sequencing Technology :: Illumina
##Assembly-Data-END##
FEATURES Location/Qualifiers
source 1..7503
/organism="Norovirus GII"
/mol_type="genomic RNA"
/strain="Richland0514"
/isolate="Hu/US/2016/GII.P2-GII.2/Richland0514"
/isolation_source="stool"
/host="Homo sapiens"
/db_xref="taxon:122929"
/country="USA"
/collection_date="27-Jan-2016"
/note="genotype: GII.P2-GII.2"
gene 4..5103
/gene="ORF1"
CDS 4..5103
/gene="ORF1"
/codon_start=1
/product="nonstructural polyprotein"
/protein_id="QBY35936.1"
/translation="MKMASNDASAAAAVNSNNDNTKSSSDGVLNNMAVTLKRALGARP
KQPAPREKPPRPPRPPTPELIKRIPPPPPNDGDEPTVMFSTAGGVSGLPELTTVGQPP
EANTAFSVPPLSQRENRDAKEPLTGAILEMWDGEIYHYGLYVEKGLVLGVHKPPAAIS
IAKVELTPLSLYWRPVYTPQYLISPDTLRKLHGELFPYTAFENNCYAFCCWVLDLNDS
WLSRRMISRTTGFFRPYQEWNRKPLPTMDDSKLKKVANIVLCALSSLFTRPIKDIIGK
LKPLNILNILASCDWTFASIVESLILLAELFDVFWTPPDVSAMIAPLLGDYELQGPED
IAVELVPVVMGGIGLVLGFTKEKIGKMLSSAASTLRACKDLGAYGLEILKLVMKWFFP
KKDEANELAMVRAIEDAVLDLEAIENNHMTTLLKDKNSLAAYMKTLDMEEEKARKLST
KSASPDIVGTINALLARIAAARSLVHRAKEELSSRPRPVVLMISGKPGIGKTHLAREL
AKKIASTLTGDQRVGLIPRNGVDHWDAYKGERVVLWDDYGMSNPIHDALRLQELADTC
PLTLNCDRIENKGKVFDSDAIIITTNLVNPAPLDYVNFEACSRRIDFLVYADAPEVEK
AKRDFPGQPDMWKDAYRPDFSHIKLQLAPQGGFDKNGNTPHGKGVMKTLTASSLVARA
SGLLHERLDEYELQGPPLSTFNFDRNKIAAFRQLAAENKYGLVDTMRVGNQLRNVTTM
DELKKAIKNITIRKCQIVYGGNTYTLESDGKGRVVVERVQNASVQINNEIAGAVHHLR
CARIRYYVKCVQEAIYSLLQIAGTVFVTSRIVSRMNIQNLWSRPLTEDADEATMKEGC
PKPRDEEEFVVSSEDIRPEGKKGKNKSGRGKKHTAFSSKGLSDEEYEEYKRIREERNG
KYSIEEYLQDRDKYYEEVAIARATEEDFCEEEEVKIRQRIFRPTRKQRKEERANLGLV
TGSEIRKRNPDDFKPKGKLWADDDRSVDYNERISFEAPPSIWSRIVNFGSGWGFWVSP
SLFITSTHVIPQGITEAFGVPIRQVQIHKSGEFCRLRFPKPIRTDVSGMILEEGAPEG
TVATILIKRTTGELMPLAARMGTHATMRIQGRTVGGQMGMLLTGSNAKSMDLGTTPGD
CGCPYIYKRGNDYIVIGVHTAAARGGNTVICATQGSEGEATLEGGDNKGTYCGAPILG
PGSAPKLSTKTKFWRSSTTPLPPGTYEPAYLGGKDPRVKGGPSLQQVMRDQLKPFTEP
RGKPPKPSVLEAAKKTIINVLEQTIDPPQKWTYAQACASLDKTTSSGFPHHVRKNEHW
NGESFTGKLADQASKANLMFEEGKHMTPVYTAALKDELVKTEKVYGKIKKRLLWGSDL
ATMVRCARSFGGLMDELKAHCVTLPIRVGMNMNEDGPIVFEKHSRYRYHYDADYSRWD
STQQRAVLAAAMEIMVKFSAEPQLAQIVAEDLLSPSVVDVGDFKISINEGLPSGVPCT
SQWNSIAHWLLTLCALSEVTDLSPDIVQANSLFSFYGDDEIVSTDIKLDPEKLTGKLR
EYGLKPTRPDKTEGPLIISEDLNGLTFLRRTVTRDPAGWFGKLDQSSILRQLYWTKGP
NHEDPFESMIPHSQRPIQLMSLLGEAALHEPSFYSKISKLVISELKEGGMDFYVPRQE
PMFRWMRFSDLSTWEGDRNLAPSLVNEDGVE"
mat_peptide 4..993
/gene="ORF1"
/product="p48"
mat_peptide 994..2091
/gene="ORF1"
/product="NTPase"
mat_peptide 2092..2628
/gene="ORF1"
/product="p22"
mat_peptide 2629..3027
/gene="ORF1"
/product="VPg"
mat_peptide 3028..3570
/gene="ORF1"
/product="Pro"
mat_peptide 3571..5100
/gene="ORF1"
/product="RdRp"
gene 5084..6712
/gene="ORF2"
CDS 5084..6712
/gene="ORF2"
/note="major capsid protein"
/codon_start=1
/product="VP1"
/protein_id="QBY35937.1"
/translation="MKMASNDAAPSTDGAAGLVPESNNEVMALEPVAGAALAAPVTGQ
TNIIDPWIRANFVQAPNGEFTVSPRNAPGEVLLNLELGPELNPYLAHLARMYNGYAGG
MEVQVMLAGNAFTAGKLVFAAVPPHFPVENLSPQQITMFPHVIIDVRTLEPVLLPLPD
VRNNFFHYNQKDDPKMRIVAMLYTPLRSNGSGDDVFTVSCRVLTRPSPDFDFTYLVPP
TVESKTKPFTLPILTLGELSNSRFPVSIDQMYTSPNEVISVQCQNGRCTLDGELQGTT
QLQVSGICAFKGEVTAHLHDNDHLYNVTITNLNGSPFDPSEDIPAPLGVPDFQGRVFG
IISQRDKQNSPGHDEPANRGHDAVVPTYTAQYTPKLGQIQIGTWQTDDLTVNQPVKFT
PVGLNDTEHFNQWVVPRYAGALNLNTNLAPSVAPVFPGERLLFFRSYIPLKGGYGSPA
IDCLLPQEWVQHFYQEAAPSMSEVALVRYINPDTGRALFEAKLHRAGFMTVSSNTSAP
VVVPANGYFRFDSWVNQFYSLAPMGTGNGRRRVQ"
gene 6712..7491
/gene="ORF3"
CDS 6712..7491
/gene="ORF3"
/note="minor structural protein; small basic protein"
/codon_start=1
/product="VP2"
/protein_id="QBY35938.1"
/translation="MAGAFVAGLAGDVLSNGLSSLINAGANAINQRAEFDFNQKLQQN
SFNHDKEMLQAQIQATKQLQADMMAIKQGVLTAGGFSPADAARGAVNAPMTQALDWNG
TRYWAPGSMRTTSYSGKFTSTAPVRQADFQHTQNRPSSGSSVSSFATQSSRPTLTTTT
GSSHGTASSNSTRSTSLSQSTVSRATSRTSEWVRDQNRNLEPYMHGALQTAFVTPPSS
RASDGTVSTVPKGVLDSWTPAFNTRRQPLFAHLRKRGESQA"
ORIGIN
1 tgaatgaaga tggcgtctaa cgacgcttct gctgccgctg ctgttaacag caacaacgac
61 aacacaaaat cttcaagtga cggagtgctt aacaacatgg ccgtcaccct taaacgagcc
121 cttggggccc ggcccaaaca gccggccccg agagaaaaac ccccaagacc ccctagacca
181 ccaacaccag aactaattaa aagaatcccc cccccaccac ctaatgatgg ggatgaacca
241 accgtgatgt ttagcactgc aggtggtgtg tctggcctac ctgagctcac aacagtcggt
301 caaccacctg aagctaacac ggcctttagc gtgccccccc tcagccaaag ggaaaacagg
361 gacgctaagg agccgctaac tggagctatt ctggaaatgt gggacgggga gatttatcac
421 tatggactgt atgtggaaaa agggcttgtg ttaggcgtgc acaagccacc ggctgccatt
481 agcatagcca aagtggaatt aacgcctctc tcactgtact ggaggcctgt gtacacgcct
541 cagtacctca tatctccaga caccttgagg aaactccacg gtgaactatt tccctataca
601 gcctttgaaa acaactgtta tgccttctgc tgttgggttt tggaccttaa cgattcatgg
661 ctaagcagga ggatgattag taggactact ggctttttca ggccctacca agagtggaac
721 aggaagcccc tcccaaccat ggatgactca aaattgaaaa aggtcgcaaa catcgttcta
781 tgtgcattgt catcattgtt cactagaccc attaaggata taattggcaa gcttaaaccc
841 ctcaacatcc tgaacatttt ggcctcgtgc gactggacct tcgctagcat agttgagtca
901 ctaatcctct tggctgaact ctttgatgtg ttctggacac ccccagatgt gtctgcaatg
961 atcgcacccc tcctcggtga ctatgagcta caaggccctg aagacatcgc tgtggagctc
1021 gtacccgttg tgatgggtgg gataggtctg gtgctgggat tcaccaaaga gaaaataggt
1081 aagatgctct cctctgcagc atcaactttg agggcatgca aagatcttgg agcctatgga
1141 ctggagatac tgaaactagt catgaaatgg ttcttcccaa agaaggatga ggccaacgaa
1201 ctggctatgg ttagagccat tgaagacgct gtattggacc tggaggccat tgagaacaac
1261 catatgacca ctctattgaa agacaagaac agccttgcag cctacatgaa gaccctggac
1321 atggaagagg aaaaagctag gaagttatcc accaaatcag cctcccctga cattgtgggc
1381 actataaatg ccctgttggc taggatcgct gccgcgcgtt ccttagttca tagggccaag
1441 gaggagctct ccagcaggcc aaggccggtc gttttgatga tctctggcaa gccagggata
1501 ggaaagaccc acttggccag agaactggca aagaaaatcg cctcaacact cacaggagac
1561 cagagagtgg gcctcatccc acggaatgga gttgaccatt gggatgccta caaaggtgag
1621 agagtggtgc tctgggatga ttacgggatg agcaacccca tccacgatgc gctgaggttg
1681 caagaactgg cagacacatg tccattgact ctaaattgtg acaggattga aaataagggg
1741 aaagtcttcg acagcgatgc gatcataatt accaccaatt tggtcaatcc cgcgccgctg
1801 gattatgtca actttgaggc ctgctccaga cgcatagact tccttgtgta tgctgatgcc
1861 ccagaagtcg agaaagcaaa gcgggacttc cccggccaac cagacatgtg gaaggacgcc
1921 tatcgccctg acttctcaca catcaaacta caacttgcac cacaaggtgg gtttgacaaa
1981 aatggtaaca cccctcatgg taaaggagtg atgaagactc tcactgccag ctcactggtt
2041 gcgcgtgcct ctggtctctt gcacgagagg ctagatgagt acgaattgca aggtccaccc
2101 ctctcaacct tcaactttga ccgcaacaaa attgcagcgt tcagacaact cgctgctgaa
2161 aacaagtatg gactggtaga cacgatgagg gtgggtaacc agctcagaaa tgttacgacc
2221 atggatgaac tcaagaaggc tatcaagaac atcacaatca gaaagtgcca gatagtctat
2281 ggtggcaaca cttacacgct tgagtctgac ggcaagggta gagttgtggt tgagagggtg
2341 cagaacgcca gcgtgcaaat caacaatgag atcgccggtg cagtacatca ccttagatgt
2401 gccagaatac ggtattatgt taagtgtgtc caagaggcca tctactcact cctccaaatt
2461 gctggcacgg tgtttgtcac ttcacgcatc gtaagccgca tgaacatcca aaatttatgg
2521 tccaggccat taactgaaga tgcagatgag gccaccatga aagaggggtg ccctaaacct
2581 agggatgaag aagaatttgt cgtctcctca gaagatatca ggccagaggg caagaaaggt
2641 aaaaacaaga gtggccgggg caagaaacac acggcgttct caagcaaagg tctcagtgat
2701 gaggagtacg aagagtacaa aaggattaga gaggagagaa atggcaaata ctccatagag
2761 gaatacctac aggacagaga caagtactat gaagaggtgg ccattgccag ggcaactgaa
2821 gaagacttct gtgaagaaga agaggttaag attcgtcaga ggatcttcag gccaactaga
2881 aagcaacgca aggaagaaag agccaacctt ggcctcgtca ccggatctga gatcagaaag
2941 aggaacccag atgactttaa accaaaagga aagctgtggg ccgacgatga taggagcgtc
3001 gactacaacg aaagaatcag ctttgaggcc ccaccaagca tttggtctag aattgtcaac
3061 tttggttctg ggtgggggtt ttgggtgtca cctagcctct tcataacatc aacacatgtc
3121 ataccccaag gcataactga agcctttggt gtacccataa ggcaagtgca aatacacaaa
3181 tcgggcgaat tctgtcgcct gagattccca aaacccatca ggacagatgt gtcaggtatg
3241 atactggagg agggagcgcc tgaaggcact gttgccacca tactcatcaa gagaaccact
3301 ggagaactga tgccccttgc agcaagaatg ggcacccacg cgactatgag gatacaaggg
3361 cgcacggtgg gcggccaaat gggaatgctg ctcactggat ccaatgcgaa gagcatggat
3421 cttggcacca cgcctggtga ctgtgggtgc ccttatattt acaaaagggg caatgattac
3481 atagtcattg gagttcacac agcagctgcc cgtggcggaa acactgtcat ctgcgccaca
3541 caaggtagtg agggtgaggc cacactcgag ggtggtgaca acaaagggac atactgtggg
3601 gcaccaatcc taggacccgg gagtgccccg aaactgagca ctaagaccaa attctggagg
3661 tcctctacaa caccactccc acctggcaca tacgagccgg catatctggg aggaaaagac
3721 ccccgagtca aaggtggacc atctctgcaa caagtcatgc gagaccaact gaagccattc
3781 accgaacccc gtggtaagcc accaaaacca agtgtccttg aagctgccaa aaagacaatt
3841 atcaatgtgc tagagcaaac aatagacccc ccacaaaagt ggacgtacgc gcaagcgtgc
3901 gcgtctcttg acaaaaccac atctagcggg tttccccacc acgtgcgcaa aaacgagcac
3961 tggaatgggg aatctttcac aggaaaattg gctgatcagg catcaaaagc aaacctaatg
4021 tttgaagagg gaaaacacat gaccccagtt tacacagctg cccttaagga tgagttggtc
4081 aaaactgaga aggtgtatgg gaagataaag aagaggttgc tttggggctc tgatctggcc
4141 acaatggtgc ggtgcgcgcg ctcttttggt ggtttgatgg acgaacttaa ggcccactgt
4201 gtaacacttc cgataagggt tggcatgaat atgaatgaag atggaccaat agtctttgag
4261 aaacattcca gatacaggta tcactatgat gcagactatt ccaggtggga ttcaacacag
4321 cagagagccg ttctggctgc ggccatggag atcatggtta aattctcagc agagccacaa
4381 ctagcccaaa tagttgcaga ggacctactg tcgcctagtg tagttgatgt gggcgacttc
4441 aaaatttcca tcaacgaagg gttaccatca ggtgtccctt gcacctctca atggaactcc
4501 attgcacact ggctcctcac cttgtgtgcc ctttctgaag ttacagatct ctctcccgat
4561 attgtgcaag ccaactccct cttctccttc tatggtgatg atgaaattgt gagtacagac
4621 attaaattag acccagaaaa gttgacgggg aagttgagag aatacggtct caaacccact
4681 cggcctgaca agactgaggg ccccctgatc attagcgagg atctgaatgg cctgaccttc
4741 ttgaggagaa ccgtcacccg cgaccctgca ggatggtttg gcaaactgga ccagagctct
4801 atactcaggc aattgtattg gaccaagggt cctaatcatg aagacccctt tgagtcaatg
4861 attccacact cccagaggcc catacaactc atgtcactct tgggcgaagc agcactgcat
4921 gaaccatcgt tttacagcaa gatcagcaag cttgtgatat ctgagttgaa agaaggtgga
4981 atggattttt acgtgcccag gcaagaaccc atgttcaggt ggatgagatt ctcggatttg
5041 agcacgtggg agggcgatcg caatcttgct cccagtcttg tgaatgaaga tggcgtcgaa
5101 tgacgccgct ccatctactg atggtgcagc cggcctcgtg ccagaaagta acaatgaggt
5161 catggctctt gaacccgtgg ctggtgccgc cttggcagcc ccagtcaccg gtcaaacaaa
5221 tattatagac ccttggatta gagcaaattt tgtccaggcc cccaacggtg aattcacagt
5281 ttctccccgt aatgcccctg gtgaagtgtt attgaatcta gagttgggtc cagaattaaa
5341 tccttatctg gcacatttag caagaatgta taacgggtat gccggtggga tggaggtgca
5401 ggtcatgttg gctgggaacg cgttcacagc cggcaagttg gtcttcgccg ctgtaccacc
5461 tcacttcccg gttgaaaacc ttagcccaca gcaaattacc atgttccctc atgtgattat
5521 agatgtaagg accttagaac ctgttttatt accacttcct gatgttagga acaatttctt
5581 ccattataat cagaaagatg atcctaaaat gagaattgtg gctatgcttt acacccccct
5641 taggtctaat ggttcaggtg atgatgtgtt cacagtctct tgcagggtgt tgactagacc
5701 ctcccctgat tttgatttca catatctggt gccaccaaca gtggaatcta aaacaaaacc
5761 attcactctc ccaatcctca cacttgggga actttccaat tctaggttcc cagtgtccat
5821 agaccagatg tacaccagcc ccaatgaggt catatcagtg cagtgtcaaa atggtaggtg
5881 cacattggac ggggagcttc aggggacaac acaactccaa gtcagtggta tttgtgcttt
5941 caagggggaa gtgaccgccc atttgcatga caatgaccac ctatataatg tcaccatcac
6001 aaacctgaat gggtccccct ttgacccctc cgaggacatt cctgcccctc tgggcgtgcc
6061 tgatttccag ggaagggtct ttggtatcat ctcccaaaga gataaacaga atagccctgg
6121 gcacgatgaa ccagcaaaca ggggacacga cgctgtggtc cctacttaca cagcacagta
6181 caccccaaaa ttgggtcaga ttcaaattgg cacatggcag accgacgatc tcacagtcaa
6241 ccaaccagtc aaatttaccc cagttggtct caatgacact gaacatttta accaatgggt
6301 ggtccccaga tacgcaggtg ccctaaacct caacacaaac cttgcccctt ctgttgctcc
6361 agtgtttcca ggagagcgcc tgcttttctt cagatcatat attcctctca agggtggtta
6421 tggaagtcca gccattgatt gcctactacc acaagagtgg gtgcaacact tctatcagga
6481 ggctgcccca tcaatgagtg aggtggccct tgtcagatac attaacccgg acactggtcg
6541 ggcactgttt gaggccaagc tccacagagc tggtttcatg acagtctcga gcaacaccag
6601 tgccccggtg gttgtgcctg ccaatggata cttcagattt gactcttggg tgaatcaatt
6661 ctattctctc gcccccatgg gaactggaaa tgggcgtaga agggttcaat aatggctgga
6721 gcttttgtag ctggtcttgc aggggacgtg ctcagcaatg ggctcagttc attaattaat
6781 gcaggtgcta atgcaataaa tcagagggca gagtttgatt ttaatcagaa attacagcaa
6841 aattctttta atcatgataa ggagatgttg caggctcaga ttcaggcaac taagcagctg
6901 caggcagaca tgatggctat taaacagggg gttctgaccg ctggcggctt ttcccctgct
6961 gatgcagcca gaggtgccgt gaatgcgccc atgacacagg cgctggactg gaacggcaca
7021 aggtattggg caccaggctc tatgaggacc acatcttatt ctgggaaatt cacatcaacc
7081 gccccagtga ggcaggccga ctttcagcac acccaaaacc ggccatcgag tggctcttct
7141 gtgtcctcct ttgccactca atcttcaagg ccaactctga ccacaaccac tgggtcctca
7201 catggcacag cctcatcaaa ttcaactcgc agcacgagcc tctcccaatc aacggtctct
7261 agagctacat ctaggactag tgagtgggtt agagatcaaa atagaaattt ggaaccctac
7321 atgcatggtg ccttacagac agcctttgtc accccaccct ccagcagggc gtctgatggg
7381 acagtctcaa ccgtcccaaa gggtgttttg gactcctgga cacctgcgtt caacacccgc
7441 aggcagccgc tctttgcaca cctccgtaag aggggggagt cacaagctta gtgaaaaggt
7501 gga
//