Typing tool
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Typing tool
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Complete norovirus genomes
| MK775028 | GII.2 | |
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| GII.P2 |
ORF1: 1..4885
ORF2: 4866..6494
ORF3: 6494..7239
LOCUS MK775028 7239 bp RNA linear VRL 15-APR-2019
DEFINITION Norovirus GII isolate Hu/US/2014/GII.P2-GII.2/Summit0246
nonstructural polyprotein (ORF1) gene, partial cds; VP1 (ORF2)
gene, complete cds; and VP2 (ORF3) gene, partial cds.
ACCESSION MK775028
VERSION MK775028.1
KEYWORDS .
SOURCE Norovirus GII
ORGANISM Norovirus GII
Viruses; Riboviria; Orthornavirae; Pisuviricota; Pisoniviricetes;
Picornavirales; Caliciviridae; Norovirus; Norwalk virus.
REFERENCE 1 (bases 1 to 7239)
AUTHORS Barclay,L., Cannon,J.L., Wikswo,M.E., Phillips,A., Browne,H.,
Montmayeur,A.M., Tatusov,R.L., Burke,R.M., Hall,A.J. and Vinje,J.
TITLE Emergence and characterization of multiple viruses associated with
a novel GII.P16 polymerase in the United States, 2015-2018
JOURNAL Unpublished
REFERENCE 2 (bases 1 to 7239)
AUTHORS Barclay,L., Cannon,J.L., Brandt,E., Montmayeur,A.M., Tatusov,R.L.,
Chhabra,P. and Vinje,J.
TITLE Direct Submission
JOURNAL Submitted (09-APR-2019) Division of Viral Diseases, Centers for
Disease Control and Prevention, 1600 Clifton Road NE, Atlanta, GA
30329, USA
COMMENT ##Assembly-Data-START##
Assembly Method :: Geneious v. R10; SPAdes v. 3.6
Sequencing Technology :: Illumina
##Assembly-Data-END##
FEATURES Location/Qualifiers
source 1..7239
/organism="Norovirus GII"
/mol_type="genomic RNA"
/strain="Summit0246"
/isolate="Hu/US/2014/GII.P2-GII.2/Summit0246"
/isolation_source="stool"
/host="Homo sapiens"
/db_xref="taxon:122929"
/country="USA"
/collection_date="20-Apr-2014"
/note="genotype: GII.P2-GII.2"
gene <1..4885
/gene="ORF1"
CDS <1..4885
/gene="ORF1"
/codon_start=2
/product="nonstructural polyprotein"
/protein_id="QBY35935.1"
/translation="PNDGDEPTVMFSTIGGVSGLPELTTVGQPPEANTAFSVPPLSQR
ENRDAKEPLTGTILEMWDGEIYHYGLYVEKGLVLGVHKPPAAISIAKVELTPLSLYWR
PVYTPQYLISPDTLRKLHGELFPYTAFENNCYAFCCWVLDLNDSWLSRRMISRTTGFF
RPYQEWNRKPLPTMDDSKLKKVANIVLCALSSLFTRPIKDIIGKLKPLNILNILASCD
WTFAGIVESLILFAELFDVFWTPPDVSAMIAPLLGDYELQGPEDIAVELVPVVMGGIG
LVLGFTKEKIGKMLSSAASTLRACKDLGAYGLEILKLVMKWFFPKKDEANELAMVRAI
EDAVLDLEAIENNHMTTLLKDKNSLAAYMKTLDMEEEKARKLSTKSASPDIVGTINAL
LARIAAARSLVHRAKEELSSRPRPVVLMISGKPGIGKTHLARELAKKIASTLTGDQRV
GLIPRNGVDHWDAYKGERVVLWDDYGMSNPIHDALRLQELADTCPLTLNCDRIENKGK
VFDSDAIIITTNLVNPAPLDYVNFEACSRRIDFLVYADAPEVEKAKRDFPGQPDMWKD
AYRSDFSHIKLQLAPQGGFDKNGNTPHGKGVMKTLTASSLVARASGLLHERLDEYELQ
GPPLSTFNFDRNKIAAFRQLAAENKYGLVDTMKVGNQLRNVTTMDELKKAIKNIIIRK
CQIVYGGNTYTLESDGKGKVVVERVQNASVQINNEIAGAVHHLRCARIRYYVKCVQEA
IYSLLQIAGTVFVTSRIVSRMNIQNFWSRPLTEDADEATMKEGCPKPREEEEFIVSSD
DIKPEGKKGKNKSGRGKKHTAFSSKGLSDEEYEEYKRIREERNGKYSIEEYLQDRDKY
YEEVAIARATEEDFCEEEEVKIRQRIFRPTRKQRKEERANLGLVTGSEIRKRNPDDFK
PKGKLWADDDRSVDYNERISFEAPPSIWSRIVNFGSGWGFWVSPSLFITSTHVIPHGI
TEAFGVPIRQVQIHKSGEFCRLRFPKPIRTDVSGMILEEGAPEGTVATILIKRTTGEL
MPLAARMGTHATMRIQGRTVGGQMGMLLTGSNAKGMDLGTTPGDCGCPYIYKRGNDYI
VIGVHTAAARGGNTVICATQGSEGEATLEGGDNKGTYCGAPILGPGNAPKLSTKTKFW
RSSTTPLPPGTYEPAYLGGKDPRVKGGPSLQQVMRDQLKPFTEPRGKPPKPSVLEAAK
KTIINVLEQTIDPPQKWTYAQACASLDKTTSSGFPHHVRKNEHWNGESFTGKLADQAS
KANLMFEEGKHMTPVYTAALKDELVKTEKVYGRIKKRLLWGSDLATMVRCARSFGGLM
DELKAHCVTLPIRVGMNMNEDGPIVFEKHSRYRYHYDADYSRWDSTQQRAVLAAAMEI
MVKFSAEPQLAQIVAEDLLSPSVVDVGDFKISINEGLPSGVPCTSQWNSIAHWLLTLC
ALSEVTDLSPDIIQANSLFSFYGDDEIVSTDIKLDPEKLTGKLREYGLKPTRPDKTEG
PLIISEDLNGLTFLRRTVTRDPAGWFGKLDQSSILRQLYWTKGPNHEDPFESMIPHSQ
RPIQLMSLLGEAALHEPSFYSKISKLVISELKEGGMDFYVPRQEPMFRWMRFSDLSTW
EGDRNLAPSLVNEDGVE"
mat_peptide <1..775
/gene="ORF1"
/product="p48"
mat_peptide 776..1873
/gene="ORF1"
/product="NTPase"
mat_peptide 1874..2410
/gene="ORF1"
/product="p22"
mat_peptide 2411..2809
/gene="ORF1"
/product="VPg"
mat_peptide 2810..3352
/gene="ORF1"
/product="Pro"
mat_peptide 3353..4882
/gene="ORF1"
/product="RdRp"
gene 4866..6494
/gene="ORF2"
CDS 4866..6494
/gene="ORF2"
/note="major capsid protein"
/codon_start=1
/product="VP1"
/protein_id="QBY35933.1"
/translation="MKMASNDAAPSTDGAAGLVPESNNEVMALEPVAGAALAAPVTGQ
TNIIDPWIRANFVQAPNGEFTVSPRNAPGEVLLNLELGPELNPYLAHLARMYNGYAGG
MEVQVMLAGNAFTAGKLVFAAVPPHFPVENLSPQQITMFPHAIIDVRTLEPVLLPLPD
VRNNFFHYNQKDDPKMRIVAMLYTPLRSNGSGDDVFTVSCRVLTRPSPDFDFTYLVPP
TVESKTKPFTLPILTLGELSNSRFPVSIDQMYTSPNEVISVQCQNGRCTLDGELQGTT
QLQVSGICAFKGEVTAHLHDNDHLYNVTITNLNGSPFDPSEDIPAPLGVPDFQGRVFG
IISQRDKHNSPGHNEPANRGHDAVVPTYTAQYTPKLGQIQIGTWQTDDLTVNQPVKFT
PVGLNDTEHFNQWVVPRYAGALNLNTNLAPSVAPVFPGERLLFFRSYIPLKGGYGNPA
IDCLLPQEWVQHFYQEAAPSMSEVALVRYINPDTGRALFEAKLHRAGFMTVSSNTSAP
VVVPANGYFRFDSWVNQFYSLAPMGTGNGRRRVQ"
gene 6494..>7239
/gene="ORF3"
CDS 6494..>7239
/gene="ORF3"
/note="minor structural protein; small basic protein"
/codon_start=1
/product="VP2"
/protein_id="QBY35934.1"
/translation="MAGAFVAGLAGDVLSNGLSSLINAGANAINQRAEFDFNQRLQQN
SFNHDKEMLQAQIQATKQLQADMMAIKQGVLTAGGFSPADAARGAVNAPMTQALDWNG
TRYWAPGSMRTTSYSGRFTSTAPVRQADLQHTQSRPSSGSSVSSFVTQSSRPTLATTT
GSSHGTASSNSTRSTNLSQSTVSRATSRTGEWVRDQNRNLEPYMHGALQTAFVTPPSS
RASDGTVSTVPKGVLDSWTPAFNTRRQPLIA"
ORIGIN
1 acccaatgat ggggacgaac caaccgtgat gtttagcact ataggtggtg tgtctggcct
61 acctgagctc acaacagttg gtcaaccacc tgaagctaac acggccttta gtgtgcctcc
121 cctcagccaa agggagaata gggacgctaa ggaaccgtta actggaacca ttctggaaat
181 gtgggatggg gagatttatc attatggtct gtatgtggaa aaagggcttg tgttaggcgt
241 gcacaagccg ccggctgcca tcagcatagc caaagtggag ttaacgcccc tctcactgta
301 ctggaggcct gtttacacgc ctcagtacct tatatctcct gacaccttga ggaaactcca
361 tggtgaatta tttccctaca cagcctttga aaacaattgt tatgccttct gctgttgggt
421 tttggacctt aacgattcat ggctaagcag aaggatgatt agtaggacta ctggcttttt
481 caggccctac caagagtgga acaggaagcc cctcccaact atggatgact caaaattgaa
541 gaaggtcgca aacatcgttc tgtgtgcatt gtcatcattg ttcactagac ccattaagga
601 cataattggc aaacttaaac ccctcaacat cctaaacatc ctggcctcat gcgactggac
661 ctttgctggc atagtagagt cactaatcct ctttgctgaa ctctttgatg tgttctggac
721 acccccagat gtgtctgcaa tgatcgcacc cctcctcggt gactacgagc tgcaaggccc
781 cgaagacatc gctgtggagc tcgtgcccgt tgttatgggt gggataggct tggtgttggg
841 attcaccaaa gagaaaatag gcaagatgct ctcctctgca gcgtcaactc tgagggcatg
901 taaagatctt ggagcctacg gattagagat cctgaaacta gtcatgaaat ggtttttccc
961 aaagaaggat gaggccaacg aactggctat ggttagagcc attgaagacg ctgtgttaga
1021 cttggaggcc attgagaaca accacatgac cactctattg aaggacaaga acagccttgc
1081 agcctacatg aagaccctgg acatggaaga ggaaaaagct aggaagctat ccaccaaatc
1141 agcctccccc gacattgtgg gcaccataaa cgccctgctg gctaggatcg ctgccgcacg
1201 ttccttggtt catagggcca aggaagagct ctccagcaga ccaaggccag tcgtcctgat
1261 gatctccggc aaaccaggga taggaaagac ccatttggcc agagaactgg caaagaaaat
1321 tgcctcaaca ctcacaggag accaaagggt gggcctcatc ccacggaatg gagttgacca
1381 ttgggacgcc tacaaaggag agagagtggt gctctgggat gactatggga tgagcaaccc
1441 cattcacgat gcactgaggt tgcaggaatt ggcagacaca tgtccactaa ctctgaattg
1501 tgacaggatt gaaaacaagg ggaaagtctt cgacagcgac gcaatcataa tcaccaccaa
1561 tttggtcaat cccgcgccgc tggattatgt caactttgag gcctgctcca gacgtataga
1621 cttccttgtg tatgctgatg ccccagaagt cgagaaagca aagcgggact tccccggtca
1681 accggacatg tggaaggacg cctatcgctc tgacttctca catattaaat tgcaacttgc
1741 accacaaggt gggttcgaca agaatggcaa caccccacat ggtaaaggag tgatgaagac
1801 tctcaccgcc agttcgctgg ttgcgcgtgc ctctggtctc ttgcatgaga gattagatga
1861 gtacgagtta cagggtccgc ccctttcaac cttcaacttt gatcgcaaca aaattgcagc
1921 gttcagacaa ctcgccgctg aaaacaagta tggtctggtg gacacgatga aggtgggcaa
1981 ccagctcaga aatgtcacga ccatggatga gctcaagaag gctatcaaaa acatcataat
2041 caggaagtgc cagatagtct atggtggcaa cacttacacg cttgaatctg acggcaaggg
2101 taaggtcgta gttgagaggg tgcagaacgc cagcgtgcaa atcaataatg agatcgctgg
2161 cgcagtacat caccttagat gtgccaggat aaggtattat gtcaagtgtg tccaagaggc
2221 catttactca ctcctccaaa tcgccggcac ggtgtttgtc acttcacgca tcgtaagccg
2281 catgaacatc caaaattttt ggtccagacc attaactgaa gatgcagatg aggccaccat
2341 gaaagagggg tgccctaaac ctagggaaga agaggagttt atcgtctctt cagacgatat
2401 caagccagag ggcaagaagg gtaaaaacaa gagtggccgg ggcaagaaac acacggcatt
2461 ctcaagcaaa ggtctcagtg atgaggaata tgaagagtac aaaaggatca gagaggagag
2521 gaatggcaag tactccatag aggaatacct acaggacaga gacaaatact atgaagaggt
2581 ggccattgcc agggcaactg aagaagactt ctgcgaagaa gaagaggtta agattcgtca
2641 aaggatcttc aggccaacaa gaaaacaacg caaggaagaa agagccaacc ttggcctcgt
2701 taccgggtct gagatcagga aaaggaaccc agatgatttc aaaccaaaag gaaagctgtg
2761 ggccgacgat gacaggagcg tcgactacaa tgaaagaatc agctttgagg ctccaccaag
2821 catttggtct agaattgtca actttggttc tggatggggg ttttgggtgt cgcccagcct
2881 cttcataaca tcaacacatg tcatacctca cggcataact gaggcctttg gtgtacccat
2941 aaggcaggtg caaatacaca aatcgggcga attctgtcga ctgagattcc caaaacccat
3001 caggacagat gtgtcaggta tgatactgga ggagggagcg cctgaaggca ctgttgccac
3061 catactcatc aaaagaacca ctggagagct gatgcctctc gcagcaagaa tgggcaccca
3121 cgcgactatg agaatacaag ggcgcacagt gggcggccag atggggatgc tgcttactgg
3181 gtccaacgca aagggcatgg atcttggcac cacgcccggt gactgcgggt gcccctacat
3241 ttacaaaagg ggcaatgact acatagtcat tggagttcac acagcagccg ctcgcggcgg
3301 aaacacagtc atctgcgcca cacaaggtag tgagggtgag gccacactcg agggtggtga
3361 caataaagga acatactgcg gggcaccaat cctaggcccc gggaatgccc caaaactgag
3421 cactaaaacc aagttctgga gatcctccac aacaccactc ccacccggca cgtacgagcc
3481 ggcatatctg ggaggaaaag acccacgagt caaaggtgga ccgtctctgc aacaagttat
3541 gcgagatcaa ctgaagccat tcaccgaacc ccgtggtaag ccaccaaaac caagtgtcct
3601 tgaagctgct aaaaagacaa ttattaatgt gctagaacaa acaatagatc ccccacaaaa
3661 atggacgtac gcacaagcgt gcgcgtctct cgacaaaacc acatctagtg ggttccccca
3721 ccacgtgcgc aaaaacgagc actggaatgg ggaatctttc acaggaaaat tggctgacca
3781 ggcgtcaaaa gcaaacctaa tgtttgaaga ggggaagcac atgaccccag tttacacagc
3841 tgcccttaag gatgagctgg tcaaaactga gaaagtgtat gggagaataa agaagaggtt
3901 gctttggggc tctgatctgg ccaccatggt gcggtgcgca cgctcctttg gcggtttgat
3961 ggacgaactc aaggcccact gtgtgacact tccgataagg gttggcatga acatgaatga
4021 agatggacca atagtctttg agaaacactc cagatatagg taccactatg atgcagacta
4081 ttccaggtgg gactcaacac agcagagagc cgttctggcc gcggccatgg agattatggt
4141 taaattctca gcagaaccac aactagccca aatagttgca gaggatctat tgtcgcctag
4201 tgtagttgac gtgggcgact tcaaaatttc catcaacgaa gggttgccat cgggtgtccc
4261 ttgcacctct caatggaact ccatcgcaca ttggctcctt actttgtgtg ccctttctga
4321 agttacagac ctctctcctg acattataca ggccaactcc ctcttctcct tctatggaga
4381 tgatgaaatt gtgagcacag atattaaatt agatccagaa aagctgacgg ggaaattgag
4441 agaatatggt ctcaaaccta ctcgtcctga caaaactgag ggtcccctga tcattagtga
4501 ggacctgaat ggcctgactt tcctgaggag aaccgtaact cgcgaccctg cgggatggtt
4561 tggcaaactg gaccaaagct ccatacttag gcaattgtat tggaccaaag gccccaatca
4621 tgaagaccct tttgagtcaa tgattccaca ctcccagaga cccatacaac tcatgtcact
4681 tttgggcgag gcagcactgc atgaaccatc attttacagc aagattagca agcttgtgat
4741 atccgaattg aaagaaggtg gaatggattt ttacgtgccc aggcaagaac ctatgttcag
4801 gtggatgagg ttctcggatt tgagcacgtg ggagggcgat cgcaatcttg ctcccagtct
4861 tgtgaatgaa gatggcgtcg aatgacgccg ctccatctac tgatggtgca gccggcctcg
4921 tgccagaaag taataatgag gtcatggctc ttgaacccgt ggctggtgcc gctttggcag
4981 ccccggtcac tggtcaaaca aatattatag acccttggat tagagcaaat tttgtccagg
5041 cccccaatgg tgaatttaca gtttctcccc gtaatgcccc tggtgaagtg ctactgaatc
5101 tggagttggg tccagaacta aatccttatc tggcacactt agcaagaatg tataacgggt
5161 acgccggtgg gatggaggtg caggtcatgc tggctgggaa cgcgttcaca gccggcaagt
5221 tggtcttcgc cgccgtgcca cctcacttcc cggttgaaaa ccttagccca caacaaatta
5281 ccatgttccc tcatgcgatt atagatgtaa ggactttgga acctgtttta ttaccactcc
5341 ctgatgttag aaataatttc ttccattaca atcagaaaga tgaccccaag atgagaattg
5401 tggctatgct ttataccccc cttaggtcta atggctcagg tgatgatgtg tttacagtct
5461 cctgtagggt gttaactaga ccctctcctg attttgactt cacatatctg gtgccaccaa
5521 cagtggagtc taaaacaaaa ccattcaccc tcccaatcct cacacttggg gaactttcca
5581 attctagatt cccagtgtct atagaccaga tgtacaccag ccctaatgaa gttatatcag
5641 tgcagtgtca aaatggtagg tgcacattgg acggggagct ccaaggaaca acacaacttc
5701 aagtcagtgg catttgtgct ttcaaggggg aagtgaccgc ccacttgcat gacaatgatc
5761 acctgtacaa tgtcaccatc acgaacttga atggatcccc ttttgatccc tctgaggaca
5821 tccctgcccc tctgggcgta cctgactttc agggaagggt ctttggcatc atctcccaaa
5881 gagacaaaca caatagccct ggacataatg aaccagcaaa caggggacac gatgctgtgg
5941 tccctactta cacagcacag tacactccaa aattgggtca gattcaaatt ggcacatggc
6001 agaccgacga tctcactgtc aaccaaccag tcaaattcac cccagttgga ctcaatgata
6061 ctgaacattt caaccaatgg gtggtcccca gatatgctgg tgccctaaac cttaatacaa
6121 accttgcccc ttctgttgct ccagtgtttc caggggagcg cctactcttt ttcagatcat
6181 acatccctct caagggtggc tatggaaatc cagccattga ttgcctacta ccacaggagt
6241 gggtgcaaca cttctatcag gaagcagccc cttcaatgag tgaggtggcc cttgtcaggt
6301 acatcaaccc ggacactggt cgggcactgt ttgaggccaa gctccacaga gctggtttca
6361 tgacggtctc aagtaacacc agtgccccgg tggttgtgcc tgccaatggg tacttcagat
6421 ttgattcttg ggtgaaccaa ttctattctc tcgcccccat gggaactgga aatgggcgta
6481 gaagggttca ataatggctg gagcttttgt agctggtctt gcaggggatg tgctcagcaa
6541 tgggctcagt tcattaatta atgcaggtgc taatgcaata aatcagaggg cagaatttga
6601 ttttaatcag agattacagc aaaattcttt caatcatgat aaggagatgt tgcaggctca
6661 gattcaggca actaagcagc tgcaagcaga catgatggct ataaagcagg gggtcctgac
6721 cgctggcggc ttttcccctg ctgatgcagc cagaggtgct gtgaatgcac ccatgacaca
6781 ggcgctggat tggaacggca caaggtattg ggcaccaggc tccatgagga ccacatctta
6841 ctctgggaga ttcacatcaa ccgccccagt gaggcaggcc gacctccagc acacccagag
6901 ccggccttcg agtggctctt ctgtgtcctc ctttgtcact cagtcttcaa ggccaacttt
6961 ggccacaacc actggatcct cacatggcac agcttcatca aattcgactc gcagtactaa
7021 cctctcccaa tcaacagttt ctagagccac atctagaact ggcgagtggg ttagagatca
7081 aaatagaaat ttggaacctt atatgcatgg tgccttgcag acagcctttg tcaccccacc
7141 ttccagtagg gcgtctgacg ggacagtctc aaccgtccca aaaggtgttt tggactcctg
7201 gacacctgcg ttcaacaccc gcaggcagcc gcttattgc
//