Typing tool
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Typing tool
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Complete norovirus genomes
| MK773571 | GII.2 | |
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| GII.P16 |
ORF1: 1..5028
ORF2: 5009..6637
ORF3: 6637..7412
LOCUS MK773571 7412 bp RNA linear VRL 14-APR-2019
DEFINITION Norovirus GII isolate Hu/US/2018/GII.P16-GII.2/CS0003 nonstructural
polyprotein (ORF1) gene, partial cds; VP1 (ORF2) gene, complete
cds; and VP2 (ORF3) gene, partial cds.
ACCESSION MK773571
VERSION MK773571.1
KEYWORDS .
SOURCE Norovirus GII
ORGANISM Norovirus GII
Viruses; Riboviria; Orthornavirae; Pisuviricota; Pisoniviricetes;
Picornavirales; Caliciviridae; Norovirus; Norwalk virus.
REFERENCE 1 (bases 1 to 7412)
AUTHORS Barclay,L., Cannon,J.L., Wikswo,M.E., Phillips,A., Browne,H.,
Montmayeur,A.M., Tatusov,R.L., Burke,R.M., Hall,A.J. and Vinje,J.
TITLE Emergence and characterization of multiple viruses associated with
a novel GII.P16 polymerase in the United States, 2015-2018
JOURNAL Unpublished
REFERENCE 2 (bases 1 to 7412)
AUTHORS Barclay,L., Cannon,J.L., Montmayeur,A.M., Tatusov,R.L., Chhabra,P.
and Vinje,J.
TITLE Direct Submission
JOURNAL Submitted (09-APR-2019) Division of Viral Diseases, Centers for
Disease Control and Prevention, 1600 Clifton Road NE, Atlanta, GA
30329, USA
COMMENT ##Assembly-Data-START##
Assembly Method :: Geneious v. R10; SPAdes v. 3.6
Sequencing Technology :: Illumina
##Assembly-Data-END##
FEATURES Location/Qualifiers
source 1..7412
/organism="Norovirus GII"
/mol_type="genomic RNA"
/strain="CS0003"
/isolate="Hu/US/2018/GII.P16-GII.2/CS0003"
/isolation_source="stool"
/host="Homo sapiens"
/db_xref="taxon:122929"
/country="USA"
/collection_date="08-Jan-2018"
/note="genotype: GII.P16-GII.2"
gene <1..5028
/gene="ORF1"
CDS <1..5028
/gene="ORF1"
/codon_start=1
/product="nonstructural polyprotein"
/protein_id="QBY34774.1"
/translation="GEGLFTNMSSTLKKALGARPKQPAPRDKPQKPPRPPTPELVKRI
PPPPPNGEEEEEPVIRYEVKSGISGLPELTTVPQPDVANTAFSVPPLSLRENREAKEP
LTGAILEMWDGEIYHYGLYVEKGLVLGVHKPPAAISMARVELTPLSLYWRVVYTPQYL
ISPETLRRLNGEAFPYTAFDNNCYAFCCWVLDLNDSWLSRRMIQRTTGFFRPYQEWNR
KPLPTMDDSKIKKVANVFLCSLSTLFTRPIKDLIGKIKPLNILNILATCDWTFAGIVE
SLILLAELFGVFWTPPDVSAMIAPLLGDYELQGPEDLAVELVPVVMGGIGLVLGFTKE
KIGKMLSSAASTLRACKDLGAYGLEILKLVMKWFFPKKEEANELAMVRAIEDAVLDLE
AIENNHMTTLLKDKDSLATYMKTLDMEEEKARRLSTKSASPDIVGTINALLARIAAAR
SLVHRAKEELSSRIRPVVVMLSGKPGIGKTHLAREVARKVASTLTGDQRVGLIPRNGV
DHWDAYKGERVVLWDDYGMSNPIHDALRIQELADTCPLTLNCDRIENKGKVFDSEVII
ITTNLANPAPLDYVNFEACSRRIDFLVYAEAPEVEKAKRDFPGQPDMWKDAFKPDFSH
IKLQLAPQGGFDKNGNTPHGKGVMKTLTTGSLIARASGLLHERMDEFELQGPTITTFN
FDRNRITAFRQLAAENKYGLVDTMKVGNQLKGVKTMEELKQAIRNVTIKRCQIIYGGS
TYDLESDGKGKVLVEKVKNTSVQTNNELAGALHHLKHARIRYYVKCVQEAVYSIIQIA
GAAFVTTRIARRMNIQELWSKPQLDQNESETKEEAPKSEDDEFIISSKDIKEEGKKGK
NKTGRGKKHTAFSSKGLSDEEYDEYKRIREERNGKYSIEEYLQDRDRYYEELAIAKAT
EEDFCEEEEIKIRQRIFRPTRKQRKEERATLGLVTGSEIRKRNPDDFKPKGKLWADDN
RSVDYNEKLDFEAPPSIWSRIVSFGSGWGFWVSPSLFITSTHVIPAGITEAFGVPINQ
IQIHKSGEFCRFRFPKPIRPDVTGMILEEGAPEGTVATVLIKRPTGELMPLAARMGTH
ATMKIQGRMVGGQMGMLLTGSNAKGMDLGTTPGDCGCPYIYKRGNDYIVIGVHTAAAR
GGNTVICATQGSEGEATLEGGDDKGTYCGAPILGPGGAPKLSTKTKFWRSSNTPLPPG
TYEPAYLGGRDPRVKGGPSLQQVMRDQLKPFTEPRGKPPRPSVLEAAKQTIINVLEQT
LDPPQKWTYAQACASLDKTTSSGHPHHVRKNEFWNGETFTGKLADQASKANLMFEEGK
HMTPVYTAALKDELVKTEKIYGKIKKRLLWGSDLSTMIRCARSFGGLMDEMKAHCISL
PVRVGMNMNEDGPIIFEKHSRYKYHYDADYSRWDSTQQRAVLAAALEIMVRFSAEPQL
AQIVAEDLLAPSVVDVGDFKITINEGLPSGVPCTSQWNSIAHWLLTLCALSEVTKLSP
DIIQANSMFSFYGDDEIVSTDIKLDPEQLTAKLKEYGLKPTRPDKTEGPLIISEDLNG
LTFLRRTVTRDPAGWFGKLDQSSILRQMYWTRGPNHEDPNETMIPHSQRPIQLMALLG
EASLHGPSFYSKISKLVITELKEGGMDFYVPRQEPMFRWMRFSDLSTWEGDRNLAPNF
VNEDGVE"
mat_peptide <1..924
/gene="ORF1"
/product="p48"
mat_peptide 925..2022
/gene="ORF1"
/product="NTPase"
mat_peptide 2023..2553
/gene="ORF1"
/product="p22"
mat_peptide 2554..2952
/gene="ORF1"
/product="VPg"
mat_peptide 2953..3495
/gene="ORF1"
/product="Pro"
mat_peptide 3496..5025
/gene="ORF1"
/product="RdRp"
gene 5009..6637
/gene="ORF2"
CDS 5009..6637
/gene="ORF2"
/note="major capsid protein"
/codon_start=1
/product="VP1"
/protein_id="QBY34775.1"
/translation="MKMASNDAAPSTDGAAGLVPESNNEVMALEPVAGAALAAPVTGQ
TNIIDPWIRANFVQAPNGEFTVSPRNAPGEVLLNLELGPELNPYLAHLARMYNGYAGG
MEVQVMLAGNAFTAGKLVFAAVPPHFPVENLSPQQITMFPHVIIDVRTLEPVLLPLPD
VRNNFFHYNQKDDPKMRIVAMLYTPLRSNGSGDDVFTVSCRVLTRPSPDFDFTYLVPP
TVESKTKPFTLPILTLGELSNSRFPVSIDQMYTSPNETISVQCQNGRCTLDGELQGTT
QLQVSGICAFKGEVTAHLHDNDHLYNVTITNLNGSPFDPSEDIPAPLGVPDFQGRVFG
IISQRDKHNSPGHNEPANRGHDAVVPTYTAQYTPKLGQIQIGTWQTDDLTVNQPVKFT
PVGLNDTEHFNQWVVPRYAGALNLNTNLAPSVAPVFPGERLLFFRSYIPLKGGYGNPA
IDCLLPQEWVQHFYQEAAPSMSEVALVRYINPDTGRALFEAKLHRAGFMTVSSNTSAP
VVVPANGYFRFDSWVNQFYSLAPMGTGNGRRRVQ"
gene 6637..>7412
/gene="ORF3"
CDS 6637..>7412
/gene="ORF3"
/note="minor structural protein; small basic protein"
/codon_start=1
/product="VP2"
/protein_id="QBY34776.1"
/translation="MAGAFVAGLAGDVLSNGFSSLINAGANAINQRAEFDFNQKLQQN
SFNHDKEMLQAQIQATKQLQADMMAIKQGVLTAGGFSPADAARGAVNAPMTQALDWNG
TRYWAPNSMRTTSYSGKFTSTAPVRQADFQHTQSRPSSGSSVSSFATQSSRPTLTTTT
GSSYGTASSNSTRSTSLSQSTVSRATSRTGEWVRDQNRSLEPYMHGALQTAFVTPPSS
RASDGTVSTVPKGVLDSWTPAFNTRRQPLFAHLRKRGESQA"
ORIGIN
1 ggtgaaggct tattcacaaa tatgtcttcc accttaaaga aagccctcgg ggctaggccc
61 aaacagcctg ccccgagaga caaaccacaa aagcccccaa gaccaccaac tcccgagttg
121 gtcaagagga tacccccccc tccacctaac ggcgaagaag aagaagaacc agtcattagg
181 tatgaggtca agagtggaat ctctggcctg cccgagctca caacagtccc ccaaccggac
241 gtggccaaca cagcattcag tgttccacca ctgagcttga gagaaaacag ggaggccaag
301 gagccgctaa caggggcaat attagagatg tgggatggag agatatacca ctatggcctg
361 tacgtggaga aaggcttagt gttgggtgtg cacaaaccac ctgcagccat aagcatggca
421 agagtggagc tgacgccgtt gtcattgtac tggcgtgtgg tgtacactcc ccaatacctc
481 atctcccctg aaaccctcag gaggctcaac ggagaggcat tcccttacac cgcctttgac
541 aacaactgct atgccttttg ctgctgggtg ttagacctca atgactcatg gcttagcagg
601 aggatgatac aaagaacaac gggcttcttc agaccttacc aagagtggaa cagaaaaccc
661 ctgcctacca tggatgactc caaaattaag aaggtagcaa atgtattcct atgttcattg
721 tccacattat tcaccagacc cataaaagac ctcataggaa aaattaaacc attgaacata
781 ttgaatatcc tggcaacgtg tgactggact tttgccggaa tagtggagtc tctgatatta
841 cttgctgaac tcttcggagt tttctggaca cccccagatg tgtctgctat gatcgctccc
901 ttactcgggg actacgagtt gcaagggcca gaagacctcg ccgttgaact cgtgcctgtg
961 gtaatggggg ggattggttt ggtgttagga ttcaccaaag agaaaattgg caaaatgttg
1021 tcctcagcag catcaacact tagggcttgc aaagatcttg gtgcctatgg cttagagata
1081 ctcaaattgg tcatgaagtg gttcttccca aagaaagagg aggccaatga gctagctatg
1141 gtgagggcca tagaggatgc tgtattagac cttgaggcaa tagaaaataa ccacatgaca
1201 accctgttga aagacaaaga cagcttagca acatacatga aaacactgga catggaggag
1261 gagaaagcca ggaggttgtc cacaaaatct gcatcccctg acatagttgg gacaatcaac
1321 gccctgctgg ctcgaatagc agcggccagg tcattagtcc acagggccaa ggaagagcta
1381 tctagtagga taaggccagt agttgttatg ttatctggca agccaggaat aggcaaaact
1441 catctggcca gggaggtggc aagaaaggtg gcatccactc tcacaggaga tcaaagagtc
1501 ggactcatac cacgaaacgg tgtggaccat tgggatgcat acaaaggtga gagagtcgtg
1561 ctgtgggacg actatggcat gagtaaccct attcatgatg ctcttcgcat acaagaattg
1621 gctgatacgt gtccccttac cttaaattgt gacagaattg aaaataaggg aaaagttttt
1681 gacagtgaag tcataataat tacaacaaac cttgccaatc cagccccact tgattatgtc
1741 aactttgagg cctgttccag gagaattgat ttcctggtgt acgctgaggc accagaagta
1801 gaaaaggcaa aacgggactt tcctggtcag ccagatatgt ggaaggacgc cttcaagccg
1861 gacttttcac acatcaagct acagcttgca ccccagggcg gctttgacaa gaatggcaac
1921 accccacatg ggaaaggagt gatgaagacc ctcactaccg gttctctgat tgcccgtgca
1981 tcaggcctac tgcatgagag gatggatgaa tttgaactcc aaggccccac aatcaccacc
2041 tttaatttcg accgaaacag aatcacggca ttcagacaat tggctgcaga aaacaagtat
2101 ggattggtgg ataccatgaa agttggcaat caattaaaag gagtgaaaac catggaagaa
2161 ctcaaacaag caatcaggaa tgtgaccatc aagaggtgcc agatcatcta cggtggttcc
2221 acgtatgacc ttgaatctga tggcaagggc aaagttttgg tggaaaaggt caagaacacc
2281 tctgtacaga ccaataacga gttggctggg gccctgcacc atctcaaaca tgcccgaatc
2341 aggtactatg tcaaatgtgt gcaagaagca gtctattcta tcatacaaat tgccggcgct
2401 gcgtttgtca ccacgcgcat cgcacgccgc atgaacatac aagaactctg gtcgaagcca
2461 caactagatc aaaatgaatc agagactaag gaagaggccc ccaagtcaga agatgacgag
2521 ttcatcatat cttctaagga catcaaggag gaaggaaaga agggcaaaaa caaaactggc
2581 cgtggcaaga aacacactgc attctccagc aagggcttga gcgatgagga gtatgacgag
2641 tacaagagga taagagaaga gagaaatggg aagtactcta tagaggagta tcttcaagac
2701 agagacaggt actatgagga gctcgccatt gccaaggcca cggaagaaga cttctgtgaa
2761 gaggaggaga tcaaaatccg tcagagaatt ttccgtccca ccaggaaaca aagaaaggaa
2821 gagagggcca cattagggct agtaacaggt tcagaaatca gaaaaagaaa ccctgatgac
2881 ttcaaaccca aagggaagct gtgggccgat gacaacagga gtgttgacta caatgagaaa
2941 ctggactttg aggccccccc aagcatatgg tctaggattg tgagctttgg ctctggctgg
3001 ggcttctggg tgtcaccaag ccttttcata acatcaactc atgtaatccc cgcaggcata
3061 acagaagcat ttggagtccc catcaaccaa attcagatcc acaaatcagg cgaattttgc
3121 cgattcagat tcccaaaacc aattagacca gatgtgacag gaatgatctt ggaagaaggt
3181 gcgcctgagg gcaccgtggc aactgtgctc atcaaacgcc ccaccggaga gctcatgcct
3241 cttgcagcca gaatgggaac acacgcaacc atgaaaattc aaggccgcat ggttggcgga
3301 cagatgggta tgttgctcac tggatcaaat gctaaaggaa tggacttggg aacaactcct
3361 ggtgactgtg gctgtcctta catctataaa aggggcaatg actatatagt cattggggtg
3421 cacactgcag cagcccgtgg tggaaacact gtcatctgtg ccacacaggg aagtgagggt
3481 gaggcaactc ttgagggtgg agatgacaaa ggaacatact gtggggcacc cattctaggc
3541 cctgggggtg caccaaaatt gagcaccaaa accaaatttt ggaggtcatc gaacacgccc
3601 cttccaccag ggacatatga gcctgcctac ctcggtggcc gtgatccgcg tgttaagggt
3661 gggccttccc tgcagcaggt gatgagagac cagttgaagc cattcactga acccaggggc
3721 aaacctccaa gaccaagtgt attggaagca gccaaacaaa ccatcatcaa tgtcctcgaa
3781 caaaccctgg accctccaca aaaatggaca tacgcacagg cgtgcgcctc acttgacaaa
3841 accacctcca gcgggcaccc ccatcacgtc cgaaagaatg aattctggaa tggtgagacc
3901 ttcactggta aactggcaga ccaagcatca aaagcaaacc taatgtttga ggaagggaaa
3961 cacatgacac cagtgtacac agcagcactc aaggacgagc tagtcaagac tgagaaaatt
4021 tatggaaaga tcaagaagag actgctctgg ggctctgact tgtccaccat gatccggtgc
4081 gctaggtcat ttggtgggct tatggacgag atgaaggcac actgcatatc actcccagtc
4141 cgagttggca tgaatatgaa tgaagatggc ccaataatat ttgagaaaca ttccagatac
4201 aaatatcact atgatgcaga ctactctcgt tgggattcaa cacaacagag ggcagttcta
4261 gcagcagcct tggaaatcat ggtcagattt tctgcagaac cacaattggc acaaatagtc
4321 gctgaggatc tgctggcccc tagtgtagta gatgtaggag actttaaaat cacaataaat
4381 gaagggctcc cttctggtgt gccatgcact tctcaatgga actccatcgc acactggctg
4441 ctaactctct gtgccttgtc tgaagtcacc aaactatccc ctgacattat acaggcaaat
4501 tccatgttct cattttacgg tgatgacgag attgtcagta ccgacataaa attggaccct
4561 gaacagttaa ccgccaaatt gaaggagtac ggcctgaaac caacccgccc agacaaaacc
4621 gagggacccc tgattatcag tgaagatttg aacggtctca ctttcctccg aaggacggtg
4681 actcgtgacc cagctggctg gtttggaaaa ctggaccaaa gctcaatttt gaggcagatg
4741 tactggacta gaggaccaaa tcatgaagac cccaatgaga caatgatacc ccattcccaa
4801 agacccatac agctcatggc actgcttggt gaagcctctc ttcacggacc ctctttctac
4861 agtaaaatca gtaaattggt cataactgaa ctcaaagaag gtgggatgga cttttacgtg
4921 ccaaggcagg aacccatgtt caggtggatg aggttttctg acttgagcac gtgggagggc
4981 gatcgcaatc tggctcccaa ttttgtgaat gaagatggcg tcgaatgacg ccgctccatc
5041 tactgatggt gcagccggcc tcgtgccaga aagtaacaat gaggtcatgg ctcttgaacc
5101 cgtggctggt gccgccttgg cagccccggt caccggtcaa acaaatatta tagacccttg
5161 gattagagca aattttgtcc aggcccccaa tggtgaattt acagtctctc cccgaaatgc
5221 ccctggtgaa gtgctactga atctagagtt gggtccagaa ttaaatcctt atctggcaca
5281 tttagcaaga atgtacaatg ggtatgccgg tgggatggag gtgcaggtca tgttggctgg
5341 gaacgcgttc acagccggca agttggtctt cgccgccgtg ccaccccact tcccggttga
5401 aaaccttagt ccacagcaaa tcaccatgtt ccctcatgtg atcatagatg tgagaacctt
5461 ggaacctgtt ttattaccac tccctgatgt taggaataac ttcttccatt ataaccagaa
5521 agatgatccc aagatgagaa ttgtggctat gctttatacc cccctcaggt ctaatggttc
5581 aggtgatgat gtgtttacag tctcctgtag agtgttgact agaccttccc ctgactttga
5641 cttcacatac ctggtgccac caacagtgga gtctaaaaca aagccattca ccctcccaat
5701 cctcacactt ggggaacttt ccaattctag gttcccagtg tccatagacc agatgtacac
5761 cagccctaat gaaactatat cagtgcagtg tcaaaatggt aggtgcacac tggacgggga
5821 gcttcaaggg acaacacaac tccaagtcag tggcatttgt gctttcaaag gtgaagtgac
5881 cgcccacttg catgacaatg atcacctata taatgtcacc atcacaaact tgaatgggtc
5941 cccttttgat ccctccgagg atatccctgc ccctttgggt gtgcctgact tccagggaag
6001 ggtttttggt atcatctccc aaagagataa acacaatagt cctgggcata atgaaccagc
6061 aaacagggga cacgacgctg tggtccctac ttacacagca cagtacactc caaaacttgg
6121 acaaattcaa attggcacat ggcaaactga cgaccttaca gtcaaccaac cagtcaaatt
6181 caccccagtt ggactcaatg acactgaaca ctttaaccaa tgggtggtcc ctaggtatgc
6241 tggtgcccta aacctcaata caaaccttgc cccttctgtt gctccagtat ttccaggaga
6301 gcgcctgctc ttcttcagat catacattcc cctcaagggc ggttatggaa acccagccat
6361 tgattgccta ctaccacaag agtgggtgca gcacttctat caggaagcag ccccttcaat
6421 gagtgaggtg gccctcgtca gatacatcaa cccggacact ggtcgggcac tgtttgaggc
6481 caagctccac agagctggtt tcatgacagt ctcgagcaac accagtgccc cggtggttgt
6541 gcctgccaac gggtacttca gatttgattc ttgggtgaac caattttatt ctctcgcccc
6601 catgggaact gggaatgggc gtagaagggt tcaataatgg ctggagcttt tgtagctggt
6661 cttgcagggg acgtgctcag caatgggttt agttcattaa tcaatgcagg tgctaatgca
6721 ataaatcaga gggcagaatt tgattttaat caaaaattgc agcaaaattc ttttaatcat
6781 gataaggaga tgttgcaggc tcagattcag gcaactaagc agctgcaggc agacatgatg
6841 gctataaaac aaggggtctt gaccgctggc ggcttttccc ctgctgatgc agccagaggt
6901 gctgtgaacg cgcccatgac acaggcgctg gattggaatg gcacaaggta ttgggcacca
6961 aactccatga ggaccacatc ttattctgga aaattcacat caaccgcccc agtgaggcag
7021 gctgacttcc agcacaccca aagccggcct tcgagtggct cctctgtgtc ttcctttgcc
7081 actcagtctt caaggccaac tctgaccaca accactggtt cctcatatgg cacagcctca
7141 tcaaattcaa ctcgcagcac aagcctctcc caatcaacgg tctccagagc tacatctagg
7201 actggtgagt gggttagaga tcaaaataga agtttggaac cctacatgca tggtgcctta
7261 cagacagcct ttgtcacccc accttccagc agggcgtctg acgggacagt ctcaaccgtc
7321 cctaaaggtg ttttggactc ctggacacct gcgtttaaca cccgcaggca gccgcttttt
7381 gcacacctcc gtaagagggg ggagtcacaa gc
//