Typing tool
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Typing tool
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Complete norovirus genomes
| MK764042 | GII.2 | |
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| GII.P16 |
ORF1: 1..5097
ORF2: 5078..6706
ORF3: 6706..7485
LOCUS MK764042 7529 bp RNA linear VRL 13-APR-2019
DEFINITION Norovirus GII isolate Hu/US/2016/GII.P16-GII.2/Nassau0300
nonstructural polyprotein (ORF1) gene, partial cds; and VP1 (ORF2)
and VP2 (ORF3) genes, complete cds.
ACCESSION MK764042
VERSION MK764042.1
KEYWORDS .
SOURCE Norovirus GII
ORGANISM Norovirus GII
Viruses; Riboviria; Orthornavirae; Pisuviricota; Pisoniviricetes;
Picornavirales; Caliciviridae; Norovirus; Norwalk virus.
REFERENCE 1 (bases 1 to 7529)
AUTHORS Barclay,L., Cannon,J.L., Wikswo,M.E., Phillips,A., Browne,H.,
Montmayeur,A.M., Tatusov,R.L., Burke,R.M., Hall,A.J. and Vinje,J.
TITLE Emergence and characterization of multiple viruses associated with
a novel GII.P16 polymerase in the United States, 2015-2018
JOURNAL Unpublished
REFERENCE 2 (bases 1 to 7529)
AUTHORS Barclay,L., Cannon,J.L., Bryant,P., Montmayeur,A.M., Tatusov,R.L.,
Chhabra,P. and Vinje,J.
TITLE Direct Submission
JOURNAL Submitted (05-APR-2019) Division of Viral Diseases, Centers for
Disease Control and Prevention, 1600 Clifton Road NE, Atlanta, GA
30329, USA
COMMENT ##Assembly-Data-START##
Assembly Method :: Geneious v. R10; SPAdes v. 3.6
Sequencing Technology :: Illumina
##Assembly-Data-END##
FEATURES Location/Qualifiers
source 1..7529
/organism="Norovirus GII"
/mol_type="genomic RNA"
/strain="Nassau0300"
/isolate="Hu/US/2016/GII.P16-GII.2/Nassau0300"
/isolation_source="stool"
/host="Homo sapiens"
/db_xref="taxon:122929"
/country="USA"
/collection_date="18-Nov-2016"
/note="genotype: GII.P16-GII.2"
gene <1..5097
/gene="ORF1"
CDS <1..5097
/gene="ORF1"
/codon_start=1
/product="nonstructural polyprotein"
/protein_id="QBX92759.1"
/translation="WLASNDATVAVACNNNNDKEKSSGEGLFTNMSSTLKKALGARPK
QPAPRDKPQKPPRPPTPELVKRIPPPPPNGEEEEEPVIRYEVKSGISGLPELTTVPQP
DVANTAFSVPPLSLRENREAKEPLTGAILEMWDGEIYHYGLYVEKGLVLGVHKPPAAV
SMARVELTPLSLYWRVVYTPQYLISPETLRRLNGEAFPYTAFDNNCYAFCCWVLDLND
SWLSRRMVQRTTGFFRPYQEWNRKPLPTMDDSKIKKVANIFLCSLSTLFTRPIKDLIG
KIKPLNILNILATCDWTFAGIVESLILLAELFGVFWTPPDVSAMIAPLLGDYELQGPE
DLAVELVPVVMGGIGLVLGFTKEKIGKMLSSAASTLRACKDLGAYGLEILKLVMKWFF
PKKEEANELAMVRAIEDAVLDLEAIENNHMTTLLKDKDSLATYMKTLDMEEEKARRLS
TKSASPDIVGTINALLARIAAARSLVHRAKEELSSRIRPVVVMISGKPGIGKTHLARE
VARKVASTLTGDQRVGLIPRNGVDHWDAYKGERVVLWDDYGMSNPIHDALRIQELADT
CPLTLNCDRIENKGKVFDSEVIIITTNLANPAPLDYVNFEACSRRIDFLVYADAPEVE
KAKRDFPGQPDMWKDAFKPDFSHIKLQLAPQGGFDKNGNTPHGKGVMKTLTTGSLIAR
ASGLLHERMDEFELQGPTITTFNFDRNRITAFRQLAAENKYGLVDTMRVGNQLKGVKT
MEELKQAIRNVTIKRCRIIYGGSTYDLESDGKGKVLVEKVKNTSVQTNNELAGALHHL
KHARIRYYVKCVQEAVYSIIQIAGAAFVTTRIARRMNIQELWSKPQLDQNESETKEEA
PKSGDDEFIISSKDIKEEGKKGKNKTGRGKKHTAFSSKGLSDEEYDEYKRIREERNGK
YSIEEYLQDRDRYYEELAIAKATEEDFCEEEEIKIRQRIFRPTRKQRKEERATLGLVT
GSEIRKRNPDDFKPKGKLWADDNRSVDYNEKLDFEAPPSIWSRIVSFGSGWGFWVSPS
LFITSTHVIPAGITEAFGVPIKQIQIHKSGEFCRFRFPKPIRPDVTGMILEEGAPEGT
VATVLIKRPTGELMPLAARMGTHATMKIQGRMVGGQMGMLLTGSNAKGMDLGTTPGDC
GCPYIYKRGNDYIVIGVHTAAARGGNTVICATQGSEGEATLEGGDDKGTYCGAPILGP
GGAPKLSTKTKFWRSSNTPLPPGTYEPAYLGGRDPRVKGGPSLQQVMRDQLKPFTEPR
GKPPRPSVLEAAKQTIINVLEQTLDPPQKWTYAQACASLDKTTSSGHPYHVRKNEFWN
GETFTGKLADQASKANLMFEEGKHMTPVYTAALKDELVKTEKIYGKIKKRLLWGSDLS
TMIRCARSFGGLMDEMKAHCISLPVRVGMNMNEDGPIIFEKHSRYKYHYDADYSRWDS
TQQRAVLAAALEIMVRFSAEPQLAQIVAEDLLAPSVVDVGDFKITINEGLPSGVPCTS
QWNSIAHWLLTLCALSEVTKLSPDIIQANSMFSFYGDDEIVSTDIKLDPEQLTAKLKE
YGLKPTRPDKTEGPLIISEDLNGLTFLRRTVTRDPAGWFGKLDQSSILRQMYWTRGPN
HEDPNETMIPHSQRPVQLMALLGESSLHGPSFYSKISKLVITELKEGGMDFYVPRQEP
MFRWMRFSDLSTWEGDRNLAPNFVNEDGVE"
mat_peptide <1..993
/gene="ORF1"
/product="p48"
mat_peptide 994..2091
/gene="ORF1"
/product="NTPase"
mat_peptide 2092..2622
/gene="ORF1"
/product="p22"
mat_peptide 2623..3021
/gene="ORF1"
/product="VPg"
mat_peptide 3022..3564
/gene="ORF1"
/product="Pro"
mat_peptide 3565..5094
/gene="ORF1"
/product="RdRp"
gene 5078..6706
/gene="ORF2"
CDS 5078..6706
/gene="ORF2"
/note="major capsid protein"
/codon_start=1
/product="VP1"
/protein_id="QBX92760.1"
/translation="MKMASNDAAPSTDGAAGLVPESNNEVMALEPVAGAALAAPVTGQ
TNIIDPWIRANFVQAPNGEFTVSPRNAPGEVLLNLELGPELNPYLAHLARMYNGYAGG
MEVQVMLAGNAFTAGKLVFAAVPPHFPVENLSPQQITMFPHVIIDVRTLEPVLLPLPD
VRNNFFHYNQKDDPKMRIVAMLYTPLRSNGSGDDVFTVSCRVLTRPSPDFDFTYLVPP
TVESKTKPFTLPILTLGELSNSRFPVSIDQMYTSPNEVISVQCQNGRCTLDGELQGTT
QLQASGICAFKGEVTAHLHDNDHLYNVTITNLNGSPFDPSEDIPAPLGVPDFQGRVFG
IISQRDKHNSPGHNEPANRGHDAVVPTYTAQYTPKLGQIQIGTWQTDDLTVNQPVKFT
PVGLNDTEHFNQWVVPRYAGALNLNTNLAPSVAPVFPGERLLFFRSYIPLKGGYGNPA
IDCLLPQEWVQHFYQEAAPSMSEVALVRYINPDTGRALFEAKLHRAGFMTVSSNTSAP
VVVPANGYFRFDSWVNQFYSLAPMGTGNGRRRVQ"
gene 6706..7485
/gene="ORF3"
CDS 6706..7485
/gene="ORF3"
/note="minor structural protein; small basic protein"
/codon_start=1
/product="VP2"
/protein_id="QBX92761.1"
/translation="MAGAFVAGLAGDVLSNGLSSLINAGANAINQRAEFDFNQKLQQN
SFNHDKEMLQAQIQATKQLQADMMAIKQGVLTAGGFSPADAARGAVNAPMTQALDWNG
TRYWAPNSMRTTSYSGKFTSTAPVRQADFQYTQSRPSSGSSVSSFATQSSRPTLTTTT
GSSHGTVSSNSTRSTSLSQSTVSRATSRTGEWVRDQNRNLEPYMHGALQTAFVTPPSS
RASDGTVSTVPKGVLDSWTPAFNTRRQPLFAHLRKRGESQA"
ORIGIN
1 tggttggcgt ctaacgacgc taccgttgcc gttgcttgca acaacaacaa cgacaaagaa
61 aaatcttcag gtgaaggctt attcacaaat atgtcttcca ccttaaagaa agccctcggg
121 gctaggccca aacagcctgc cccgagagac aaaccacaaa agcccccaag accaccaact
181 cccgagttgg tcaagaggat accccctcct ccacctaatg gcgaagaaga agaagaacca
241 gtcattaggt atgaggttaa gagtgggatc tctggcctgc ccgagctcac aacagtcccc
301 caaccggacg tggccaacac agcattcagt gttccaccac tgagcttgag agaaaacagg
361 gaggccaagg aaccgctaac aggggcaata ttagagatgt gggatggaga gatataccac
421 tatggcctgt acgtggagaa aggcttagtg ttgggtgtgc acaaaccacc tgcagccgta
481 agcatggcaa gagtggagct gacgccgctg tcattgtact ggcgtgtggt gtacactccc
541 caatacctca tctcccctga aactctcagg agactcaacg gagaggcatt cccttacacc
601 gcctttgaca ataactgcta tgccttttgc tgctgggtgt tagacctcaa tgactcatgg
661 cttagcagga ggatggtgca aagaacaacg ggcttcttca gaccttatca agagtggaac
721 agaaaacccc tgcccaccat ggatgactcc aaaatcaaga aggtagcaaa tatattccta
781 tgctcattgt ccacattatt caccagaccc ataaaagacc tcataggaaa aattaaacca
841 ttaaacatat tgaatatcct ggcaacgtgt gactggactt ttgccggaat agtggagtct
901 ctgatattac ttgctgaact cttcggagtt ttctggacac ccccagatgt gtctgctatg
961 atcgctccct tactcgggga ctacgagttg caggggccag aagacctcgc cgttgaactc
1021 gtacctgtgg taatgggggg gattggtttg gtgttgggat tcaccaaaga gaaaattggc
1081 aaaatgttgt cctcagcagc atcaacactc agggcttgca aagatcttgg tgcctatggc
1141 ttagagatac tcaaattggt catgaagtgg ttcttcccaa agaaagagga ggccaatgag
1201 ttagccatgg tgagggccat agaggatgct gtactagatc ttgaggcaat agaaaataac
1261 cacatgacaa ccctgttgaa agacaaagac agcttggcaa catacatgaa aacactggac
1321 atggaggagg agaaagccag gaggttgtcc acaaaatctg catcccctga catagttggg
1381 acaatcaacg ccctgctggc tcgaatagca gcggccaggt cattagtcca cagggccaag
1441 gaagagctat ctagcaggat aagaccagta gttgtcatga tatctggcaa accaggaata
1501 ggcaaaactc atctggccag ggaggtggca agaaaggtgg cgtccactct cacaggggat
1561 caaagagtcg gactcatacc aagaaacggt gtggaccatt gggatgcata taaaggtgag
1621 agggtcgtgc tgtgggacga ctatggcatg agtaacccca tacatgatgc tcttcgcata
1681 caagaattgg ctgatacgtg tccccttacc ttaaattgtg acagaattga aaacaaggga
1741 aaagtttttg acagtgaggt cataataatt acaacaaacc ttgccaatcc agccccactt
1801 gattatgtta attttgaggc ctgttccagg agaattgatt tcctggtgta cgctgatgca
1861 ccagaagtag aaaaggcaaa acgggacttt cctggtcagc cagatatgtg gaaggacgcc
1921 ttcaagccgg acttttcaca catcaagcta cagcttgcac cccagggcgg ctttgacaag
1981 aatggcaaca ccccacatgg gaaaggagtg atgaagaccc tcactaccgg ttctctgatt
2041 gcccgtgcat caggcctact gcatgagagg atggatgaat ttgaactcca aggtcccaca
2101 atcaccacct tcaatttcga ccggaacaga atcacagcat tcagacaatt ggctgcagaa
2161 aacaagtatg gattggtgga taccatgaga gttggcaatc aactaaaagg agtgaaaacc
2221 atggaggaac ttaaacaggc aatcaggaat gtgaccatca agaggtgccg gatcatctac
2281 ggtggctcca cgtatgacct tgaatctgat ggcaagggca aagttttggt ggaaaaggtc
2341 aagaacacct ctgtacagac caacaacgag ttggctgggg ccctgcacca tctcaaacac
2401 gcccgaatca ggtactatgt caaatgtgtg caagaagcag tctattccat catacaaatt
2461 gccggcgctg cgtttgtcac cacgcgcatt gcacgccgca tgaacataca agaactctgg
2521 tcgaagccac aattagatca aaatgaatca gagactaagg aagaggcccc caagtcagga
2581 gatgacgagt tcatcatatc ttctaaggac atcaaggagg aaggaaagaa gggcaaaaac
2641 aaaactggcc gtggcaagaa acacactgca ttctccagca agggcttgag cgatgaggag
2701 tatgacgagt acaagaggat aagagaagag aggaatggga aatactccat agaggagtat
2761 cttcaagaca gagacaggta ctatgaggag ctcgccattg ccaaggccac ggaagaagac
2821 ttctgtgaag aggaggagat caaaatccgt cagagaattt tccgtcccac caggaaacaa
2881 agaaaggaag agagggccac attagggcta gtaacaggtt cagaaatcag aaaaagaaac
2941 cccgatgact tcaaacccaa agggaagctg tgggccgatg acaacaggag tgttgactac
3001 aatgagaaac tggactttga ggccccccca agcatatggt ctaggattgt gagctttggt
3061 tctggctggg gcttctgggt gtcaccaagc cttttcataa cgtcaactca tgtaatcccc
3121 gcaggcataa cagaagcatt tggagtcccc atcaaacaaa ttcagatcca caaatcaggt
3181 gaattttgcc gatttagatt cccaaaacca attagaccag atgtgacagg gatgatcttg
3241 gaagaaggtg cgcctgaggg caccgtggca actgtgctca tcaaacgccc caccggagag
3301 ctcatgcctc ttgcagccag aatgggaaca cacgcaacca tgaaaattca aggccgcatg
3361 gttggcggac agatgggtat gttgctcact ggatcaaatg ctaaaggaat ggatttggga
3421 acaactcctg gtgactgtgg ctgtccttac atctataaaa ggggcaatga ctatatagtc
3481 attggggtgc acactgcagc agcccgtggt ggaaacaccg tcatctgtgc cacacaggga
3541 agtgagggtg aggcaactct tgagggtgga gatgacaaag gaacatactg tggggcaccc
3601 attctaggcc ctgggggtgc accaaaattg agcaccaaaa ccaaattttg gaggtcatcg
3661 aacacgcccc ttccaccagg gacatatgaa cctgcctacc tcggtggccg tgatccgcgt
3721 gttaagggtg ggccctccct gcagcaggta atgagagacc agttgaagcc attcactgaa
3781 cccaggggca aacctccaag accaagtgta ttggaagcag ccaaacaaac catcatcaat
3841 gtcctcgaac aaaccctgga ccctccacaa aaatggacat acgcacaggc gtgtgcctca
3901 cttgacaaaa ccacctccag cgggcatccc tatcacgtcc gaaagaatga attctggaat
3961 ggtgagacct tcactggtaa attggcagac caagcatcaa aagcaaacct aatgtttgag
4021 gaagggaaac acatgacacc agtgtacaca gcagcactca aggacgagct agtcaagact
4081 gagaaaatct atggaaagat caagaagaga ctgctctggg gctctgactt gtccaccatg
4141 atccggtgcg ctaggtcatt tggtgggctc atggacgaga tgaaggcaca ctgcatatca
4201 ctcccagtcc gagttggcat gaatatgaat gaagatggcc caataatatt tgagaaacat
4261 tccagataca aatatcacta tgatgcagac tactctcgtt gggattcaac acaacagagg
4321 gcagtactag cagcagcctt ggaaattatg gtcagattct ctgcagaacc acaattggca
4381 caaatagtcg ctgaggatct gctggcccct agtgtagtag atgtaggaga ctttaaaatt
4441 acaataaatg aagggctccc ctctggtgtg ccatgcactt ctcaatggaa ctccatcgca
4501 cactggctgc taactctctg tgccttgtct gaagtcacca aactgtcccc tgacattata
4561 caggcaaatt ccatgttctc attttacggt gatgacgaga ttgtcagcac cgacataaaa
4621 ttggaccctg aacagctaac cgccaaattg aaggagtacg gcctgaaacc aacccgccca
4681 gacaaaaccg agggacccct gattatcagt gaagatttga acggactcac tttcctccga
4741 aggacagtga ctcgtgaccc agctggctgg tttggaaaac tggaccaaag ctcaattttg
4801 aggcagatgt actggactag aggaccaaat catgaagacc ccaatgaaac aatgataccc
4861 cattctcaaa gacccgtaca gctcatggca ctgcttggtg aatcctctct tcacggaccc
4921 tctttctaca gtaaaatcag taaattggtc ataactgaac tcaaagaagg tgggatggac
4981 ttttacgtgc caaggcagga acccatgttc aggtggatga ggttttctga cttgagcacg
5041 tgggagggcg atcgcaatct ggctcccaat tttgtgaatg aagatggcgt cgaatgacgc
5101 cgctccatct actgatggtg cagccggcct cgtgccagaa agtaacaatg aggtcatggc
5161 tcttgaaccc gtggctggtg ccgccttggc agccccggtc actggtcaaa caaatattat
5221 agacccttgg attagagcaa attttgtcca ggcccccaat ggtgaattta cagtctctcc
5281 ccgtaatgcc cctggtgaag tgctactgaa tctagagttg ggtccagaat taaatcctta
5341 tctggcacat ttagcaagaa tgtacaatgg gtatgccggt gggatggagg tgcaggtcat
5401 gttggctggg aacgcgttca cagccggcaa gttggtcttc gccgccgtgc cacctcactt
5461 cccagttgaa aaccttagcc cacagcaaat caccatgttc cctcatgtga tcatagatgt
5521 gagaaccttg gaacctgttc tgttaccact ccctgatgtt aggaataatt tcttccatta
5581 taatcagaaa gatgatccca agatgagaat tgtggctatg ctttataccc ccctcaggtc
5641 taatggttca ggtgatgatg tgtttacagt ctcctgcaga gtgttgacta gaccttcccc
5701 tgactttgac ttcacatacc tggtgccacc aacagtggag tctaaaacaa aaccattcac
5761 cctcccaatc ctcacacttg gggaactttc caattccagg ttcccagtgt ccatagacca
5821 gatgtatacc agccctaatg aagttatatc agtgcagtgt caaaatggta ggtgcacact
5881 ggacggggag ctccagggga caacacaact ccaagccagt ggcatttgtg ctttcaaagg
5941 tgaagtgacc gcccacttgc atgacaatga tcacctatat aatgtcacca tcacaaactt
6001 gaatgggtcc ccttttgatc cctccgagga catccctgcc cctctgggtg tgcctgactt
6061 ccaaggaagg gtttttggta tcatctccca aagggacaaa cacaatagtc ctgggcataa
6121 tgaaccagca aacaggggac acgacgctgt ggtccccact tacacagcac agtacactcc
6181 aaaactggga caaattcaaa ttggcacatg gcagactgac gaccttacag tcaaccaacc
6241 agtcaaattc accccagttg gactcaatga cactgaacat tttaaccaat gggtggtccc
6301 caggtatgct ggtgccctaa acctcaatac aaaccttgct ccttctgttg ctccagtatt
6361 tccaggagag cgcctgctct tcttcagatc atacattccc ctcaagggcg gttatggaaa
6421 cccagccatt gattgcctac taccacaaga gtgggtgcaa cacttctatc aggaagcagc
6481 cccttcaatg agtgaggtgg ccctcgtcag atacatcaac ccggacactg gtcgggcact
6541 gtttgaggcc aagctccaca gagctggttt catgacagtc tcgagcaaca ccagtgcccc
6601 ggtggttgtg cctgccaacg gatacttcag atttgattct tgggtgaacc aattctattc
6661 tctcgccccc atgggaactg ggaatgggcg tagaagggtt caataatggc tggagctttt
6721 gtagctggtc ttgcagggga cgtgctcagc aatgggctta gttcattaat caatgcaggt
6781 gctaatgcaa taaatcagag ggcagaattt gattttaatc agaaattgca gcaaaattct
6841 tttaatcatg ataaggagat gttgcaggct cagattcagg caactaaaca gctgcaggca
6901 gacatgatgg ctataaaaca aggggtcttg accgctggcg gcttttcccc tgctgatgca
6961 gccagaggtg ctgtgaacgc gcccatgaca caagcgctgg attggaatgg tacaaggtat
7021 tgggcaccaa actccatgag gaccacatct tattctggaa aattcacatc aaccgcccca
7081 gtgaggcagg ccgacttcca gtacacccaa agccggcctt cgagtggctc ctctgtgtct
7141 tcctttgcca ctcagtcttc aaggccaacc ctgaccacaa ccactggttc ctcacatggc
7201 acagtctcat caaattcaac tcgcagcaca agcctctccc aatcaacggt ctccagagct
7261 acatctagga ctggtgagtg ggttagagat caaaatagaa atttggaacc ctacatgcat
7321 ggtgccttac agacagcctt tgtcacccca ccttccagca gggcatctga cgggacagtc
7381 tcaaccgtcc cgaaaggtgt tttggactcc tggacacctg cgtttaacac ccgcaggcag
7441 ccgctttttg cacacctccg taagaggggg gagtcacaag cttagtgaaa aggtgaaaat
7501 ttatttagga tgaattgatt ttaccttct
//