Typing tool
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Typing tool
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Complete norovirus genomes
| MK764040 | GII.2 | |
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| GII.P2 |
ORF1: 5..5101
ORF2: 5082..6710
ORF3: 6710..7489
LOCUS MK764040 7529 bp RNA linear VRL 13-APR-2019
DEFINITION Norovirus GII isolate Hu/US/2016/GII.P2-GII.2/Cambria0299, complete
genome.
ACCESSION MK764040
VERSION MK764040.1
KEYWORDS .
SOURCE Norovirus GII
ORGANISM Norovirus GII
Viruses; Riboviria; Orthornavirae; Pisuviricota; Pisoniviricetes;
Picornavirales; Caliciviridae; Norovirus; Norwalk virus.
REFERENCE 1 (bases 1 to 7529)
AUTHORS Barclay,L., Cannon,J.L., Wikswo,M.E., Phillips,A., Browne,H.,
Montmayeur,A.M., Tatusov,R.L., Burke,R.M., Hall,A.J. and Vinje,J.
TITLE Emergence and characterization of multiple viruses associated with
a novel GII.P16 polymerase in the United States, 2015-2018
JOURNAL Unpublished
REFERENCE 2 (bases 1 to 7529)
AUTHORS Barclay,L., Cannon,J.L., Bryant,P., Montmayeur,A.M., Tatusov,R.L.,
Chhabra,P. and Vinje,J.
TITLE Direct Submission
JOURNAL Submitted (05-APR-2019) Division of Viral Diseases, Centers for
Disease Control and Prevention, 1600 Clifton Road NE, Atlanta, GA
30329, USA
COMMENT ##Assembly-Data-START##
Assembly Method :: Geneious v. R10; SPAdes v. 3.6
Sequencing Technology :: Illumina
##Assembly-Data-END##
FEATURES Location/Qualifiers
source 1..7529
/organism="Norovirus GII"
/mol_type="genomic RNA"
/strain="Cambria0299"
/isolate="Hu/US/2016/GII.P2-GII.2/Cambria0299"
/isolation_source="stool"
/host="Homo sapiens"
/db_xref="taxon:122929"
/country="USA"
/collection_date="24-Feb-2016"
/note="genotype: GII.P2-GII.2"
gene 5..5101
/gene="ORF1"
CDS 5..5101
/gene="ORF1"
/codon_start=1
/product="nonstructural polyprotein"
/protein_id="QBX92755.1"
/translation="MKMASNDASAAAAVNSNNDNTKSSSDGMLNNMAVTLKRALGARP
KQPAPREKPPRPPRPPTPELIKRIPPPPPNDGDEPTVMFSTVGGVSGLPELTTVGQPP
EANTAFSVPPLSQRENRDAKEPLTGTILEMWDGEIYHYGLYVERGLVLGVHKPPAAIS
IAKVELTPLSLYWRPVYTPQYLISPDSLRKLHGELFPYTAFENNCYAFCCWVLDLNDS
WLSRRMISRTTGFFRPYQEWNRKPLPTMDDSKLKKVANIVLCALSSLFTRPIKDIIGK
LKPLNILNILASCDWTFAGIVESLILLAELFDVFWTPPDVSAMIAPLLGDYELQGPED
IAVELVPVVMGGIGLVLGFTKEKIGKMLSSAASTLRACKDLGAYGLEILKLVMKWFFP
KKDEANELSMVRAIEDAVLDLEAIENNHMTTLLKDKNSLAAYMKTLDMEEEKARKLST
KSASPDIVGTINALLARIAAARSLVHRAKEELSSRPRPVVLMISGKPGIGKTHLAREL
AKKIASTLTGDQRVGLIPRNGVDHWDAYKGERVVLWDDYGMSNPIHDALRLQELADTC
PLTLNCDRIENKGKVFDSDAIIITTNLVNPAPLDYVNFEACSRRIDFLVYADAPEVEK
AKRDFPGQPDMWKDAYHSDFSHIKLQLAPQGGFDKNGNTPHGKGVMKTLTASSLIARA
SGLLHERLDEYELQGPPLSTFNFDRNKIAAFRQLAAENKYGLVDTMRVGNQLRNVTTM
DELKKAIKNIIIGKCQIVYGGNTYTLESDGKGKVVVERVQSTSVQINNEIAGAVHHLR
CARIRYYVKCVQEAIYSLLQIAGTVFVTSRIVSRMNIQNLWSRPLTEEADEATMKEGC
PKPREEEEFVVSSDDIKPEGKKGKNKSGRGKKHTAFSSKGLSDEEYEEYKRIREERNG
KYSIEEYLQDRDKYYEEVAIARATEEDFCEEEEVKIRQRIFRPTRKQRKEERANLGLV
TGSEIRKRNPDDFKPKGKLWADDDRSVDYNERISFEAPPSIWSRIVNFGSGWGFWVSP
SLFITSTHVIPQGITEAFGVPIRQVQIHKSGEFCRLRFPKPIRTDVSGMILEEGAPEG
TVATILIKRTTGELMPLAARMGTHATMRIQGRTVGGQMGMLLTGSNAKSMDLGTTPGD
CGCPYIYKRGNDYIVIGVHTAAARGGNTVICATQGSEGEATLEGGDKGTYCGAPILGP
GNAPKLSTKTKFWRSSTTPLPPGTYEPAYLGGKDPRVKGGPSLQQVMRDQLKPFTEPR
GKPPKPSVLEAAKKTIINVLEQTIDPPQKWTYAQACASLDKTTSSGFPHHVRKNEHWN
GESFTGKLADQASKANLMFEEGKHMTPVYTAALKDELVKTEKVYGKIKKRLLWGSDLA
TMVRCARSFGGLMDELKAHCVTLPIRVGMNMNEDGPIVFEKHSRYRYHYDADYSRWDS
TQQRAVLAAAMEIMVKFSAEPQLAQIVAEDLLSPSVVDVGDFKISINEGLPSGVPCTS
QWNSIAHWLLTLCALSEVTDLSPDIVQANSLFSFYGDDEIVSTDIKLDPEKLTGKLRE
YGLKPTRPDKTEGPLIISEDLNGLTFLRRTVTRDPAGWFGKLDQSSILRQLYWTKGPN
HEDPFESMIPHSQRPIQLMSLLGEAALHEPSFYSKISKLVISELKEGGMDFYVPRQEP
MFRWMRFSDLSTWEGDRNLAPSLVNEDGVE"
mat_peptide 5..994
/gene="ORF1"
/product="p48"
mat_peptide 995..2092
/gene="ORF1"
/product="NTPase"
mat_peptide 2093..2629
/gene="ORF1"
/product="p22"
mat_peptide 2630..3028
/gene="ORF1"
/product="VPg"
mat_peptide 3029..3568
/gene="ORF1"
/product="Pro"
mat_peptide 3569..5098
/gene="ORF1"
/product="RdRp"
gene 5082..6710
/gene="ORF2"
CDS 5082..6710
/gene="ORF2"
/note="major capsid protein"
/codon_start=1
/product="VP1"
/protein_id="QBX92753.1"
/translation="MKMASNDAAPSTDGAAGLVPESNTEVMALEPVAGAALAAPVTGQ
TNIIDPWIRANFVQAPNGEFTVSPRNAPGEVLLNLELGPELNPYLAHLARMYNGYAGG
MEVQVMLAGNAFTAGKLVFAAVPPHFPVENLSPQQITMFPHVIIDVRTLEPVLLPLPD
VRNNFFHYNQKDDPKMRIVAMLYTPLRSNGSGDDVFTVSCRVLTRPSPDFDFTYLVPP
TVESKTKPFTLPILTLGELSNSRFPVSIDQMYTSPNEVISVQCQNGRCTLDGELQGTT
QLQVSGICAFKGEVTAHLHDNDHLYNITITNLNGSPFDPSEDIPAPLGVPDFQGRVFG
IISQRDKHNSPGHNEPANRGHDAVVPTYTAQYTPKLGQIQIGTWQTDDLTVNQPVKFT
PVGLNDTEHFNQWVVPRYAGALNLNTNLAPSVAPVFPGERLLFFRSYIPLKGGYGNPA
IDCLLPQEWVQHFYQEAAPSMSEVALVRYINPDTGRALFEAKLHRAGFMTVSSNTSAP
VVVPVNGYFRFDSWVNQFYSLAPMGTGNGRRRVQ"
gene 6710..7489
/gene="ORF3"
CDS 6710..7489
/gene="ORF3"
/note="minor structural protein; small basic protein"
/codon_start=1
/product="VP2"
/protein_id="QBX92754.1"
/translation="MAGAFVAGLAGDVLSNGLSSLINAGANAINQRAEFDFNQKLQQN
SFNHDKEMLQAQIQATKQLQADMMAIKQGVLTAGGFSPADAARGAVNAPMTQALDWNG
TRYWAPGSMRTTAYSGRFTSTAPVRQADFQHTQSRPTSGSSVSSFATQSSRPTLTTTT
GSSLGTASSNSTRSTNLSQSTVSRAASRTGEWVRDQNRNLEPYMHGALQTAFVTPPSS
RASDGTVSTVPKGVLDSWTPAFNTRRQPLFAHLRKRGESQA"
ORIGIN
1 gtgaatgaag atggcgtcta acgacgcttc tgctgccgct gctgttaaca gcaacaacga
61 caacacaaaa tcttcaagtg acggaatgct taacaacatg gccgtcaccc ttaaacgagc
121 ccttggggcc cggcccaaac agccggcccc gagggagaaa cccccaagac cccctagacc
181 accaacacca gaattgatca aaagaatccc ccccccacca cccaatgatg gggacgaacc
241 aaccgtgatg tttagcactg taggtggcgt gtctggtcta cctgagctca caacagttgg
301 ccaaccacct gaagctaaca cggcctttag tgtgcctccc ctcagccaaa gggagaatag
361 ggacgctaag gaaccgttaa ctggaaccat tctggaaatg tgggatgggg agatttatca
421 ttatggactg tatgtggaaa gagggcttgt gttaggcgtg cacaagccgc cggctgccat
481 cagcatagcc aaagtggagt taacgcccct ctcactgtac tggagacctg tttacacgcc
541 tcagtacctt atatctcccg actccttgag gaaactccat ggtgaattgt ttccctacac
601 agcctttgaa aacaactgtt atgctttctg ctgttgggtt ttggatctta acgattcatg
661 gctaagcagg aggatgatta gtaggactac tggctttttc aggccctacc aggagtggaa
721 caggaagccc ctcccaacta tggatgactc aaaattgaag aaggtcgcaa acatcgttct
781 gtgtgcattg tcatcactgt tcactagacc cattaaggac ataattggca aactcaaacc
841 cctcaacatc ctaaatatcc tggcctcatg tgactggacc tttgctggca tagtggagtc
901 actaatcctc ttggctgaac tctttgatgt gttctggaca cccccagatg tgtctgcaat
961 gatcgcaccc ctcctcggtg actacgagct gcaaggcccc gaagacatcg ctgtggagct
1021 cgtgcccgtt gttatgggtg ggataggctt ggtgttggga ttcaccaaag agaaaatagg
1081 taagatgctc tcctctgcag cgtcaactct gagggcatgt aaagatcttg gagcctacgg
1141 gttggagatc ctaaaactag tcatgaaatg gtttttccca aagaaagatg aggccaacga
1201 actgtctatg gttagagcca ttgaagacgc tgtactagac ctggaggcaa ttgagaacaa
1261 ccatatgacc actctattga aagacaagaa cagccttgca gcctacatga agaccttgga
1321 catggaagag gaaaaagcca ggaaactatc caccaaatca gcctcccctg acattgtggg
1381 caccataaac gccctactgg ctaggatcgc tgccgcacgt tccttagttc atagggccaa
1441 ggaggagctc tccagtagac caagaccagt cgttctgatg atctctggca aaccagggat
1501 aggaaagacc catctggcca gagaattggc aaagaaaatt gcatcaacac tcacaggaga
1561 ccaaagggtg ggtcttatcc cacggaatgg agttgaccat tgggacgcct acaaaggtga
1621 gagagtggtg ctctgggatg actacggtat gagcaatccc atccacgatg cactgaggtt
1681 gcaggaactg gcagacacat gtccactaac tctgaattgt gacaggattg aaaacaaggg
1741 gaaagtcttc gacagcgacg cgatcataat cactaccaat ttggtcaatc ccgcgccgct
1801 ggactatgtc aactttgagg cttgctccag acgtatagac tttcttgtgt atgctgatgc
1861 cccagaagtc gagaaagcaa agcgggactt ccccggtcaa ccggacatgt ggaaggacgc
1921 ctatcactct gatttctcac atattaaatt gcaacttgca ccacaaggtg ggtttgacaa
1981 aaatggcaac accccacatg gtaaaggagt gatgaagact ctcactgcca gttcactgat
2041 tgcgcgtgcc tctggtctct tgcacgagag attagatgag tacgagttac agggtccgcc
2101 cctttcaacc ttcaactttg accgcaacaa aattgcagcg ttcagacaac tcgccgctga
2161 aaataagtat ggtttggtgg acacgatgag ggtgggcaac cagcttagga atgtcacgac
2221 catggatgaa ctcaagaagg ctatcaaaaa cattataatc gggaagtgcc agatagtcta
2281 tggcggcaac acttacacgc ttgagtctga cggcaagggc aaggttgttg ttgagagggt
2341 gcagagcacc agcgtgcaaa ttaacaatga gatcgctggt gcagtgcatc accttagatg
2401 tgccaggata aggtactatg tcaaatgtgt ccaagaggcc atctactcac tcctccaaat
2461 cgccggcacg gtgtttgtca cctcacgcat cgtaagccgc atgaacattc aaaatttatg
2521 gtccagacca ttaactgaag aagcagatga ggcaaccatg aaagaggggt gccctaaacc
2581 tagggaagaa gaggagtttg tcgtctcttc ggatgacatc aagccagagg gcaagaaagg
2641 taagaacaag agtggccggg gcaagaaaca cacggcattt tcaagtaaag gtctcagtga
2701 tgaggagtat gaagagtaca aaaggatcag agaggagaga aacggcaaat actccataga
2761 ggaataccta caggacagag acaaatacta tgaagaggtg gccattgcca gggcaactga
2821 agaagacttc tgtgaagaag aagaggttaa gattcgccag aggatcttca ggccaacaag
2881 aaagcaacgc aaggaagaaa gagccaacct tggcctcgtc accggatctg agatcaggaa
2941 gaggaatcca gatgacttca aaccaaaagg aaagctgtgg gccgacgatg acaggagcgt
3001 cgactacaac gaaagaatca gctttgaggc cccaccgagc atttggtcta gaattgttaa
3061 ctttggttct ggatgggggt tttgggtgtc acccagcctc ttcataacat caacacatgt
3121 catacctcaa ggtataactg aggcctttgg tgtacccata aggcaggttc aaatacacaa
3181 atcgggcgaa ttctgtcgtc tgagattccc aaaacccatc aggacggatg tgtcaggtat
3241 gatactggag gagggagcgc ctgaaggcac tgttgccacc atactcatca aaagaaccac
3301 tggagagctg atgcctcttg cagcaagaat gggcacccac gcgaccatga gaatacaagg
3361 acgcacggtg ggcggccaga tggggatgct gcttactggg tccaacgcaa agagcatgga
3421 tcttggcacc acgcccggtg actgtgggtg tccctacatt tacaaaaggg gcaacgacta
3481 catagtcatt ggagtccaca cagcagccgc tcgtggcgga aacactgtca tctgcgccac
3541 acaaggtagt gaaggtgagg caacactcga gggtggtgat aaaggaacat actgtggggc
3601 accaatccta ggccccggga acgccccaaa actgagcacc aaaactaagt tctggaggtc
3661 ctcaactaca ccactcccac ccggcacgta cgagccggca tatctgggag gaaaagaccc
3721 ccgagtcaaa ggtggaccat ctctgcaaca agttatgcga gaccaactga agccattcac
3781 tgaaccccgt ggcaagccac caaaaccaag tgtccttgaa gctgctaaaa agacaatcat
3841 caatgtgcta gaacaaacaa tagacccccc acaaaaatgg acgtacgcgc aagcgtgcgc
3901 gtcccttgac aaaaccacat ctagtgggtt cccccaccac gtgcgcaaga acgagcactg
3961 gaatggggaa tctttcacag gaaaattggc tgaccaggca tcaaaagcaa acttaatgtt
4021 tgaagagggg aagcacatga ctccagttta cacagctgcc cttaaggatg agctggtcaa
4081 aactgagaag gtgtatggaa aaataaagaa gaggttgctt tggggctctg acctggccac
4141 catggtgcgg tgcgcgcgct cctttggcgg tctgatggac gaactcaaag cccactgtgt
4201 gacacttccg ataagggttg gcatgaacat gaatgaagat ggaccaatag tctttgagaa
4261 acattccaga tataggtatc actatgatgc agactattcc aggtgggact caacacagca
4321 aagagccgtt ctggccgcgg ccatggagat catggttaaa ttctcagcag aaccacaact
4381 agcccaaata gttgcagagg atctattgtc gcctagtgta gttgacgtgg gcgacttcaa
4441 aatttccatc aatgaagggt tgccatcggg tgtcccttgc acctctcagt ggaattccat
4501 cgcacattgg ctcctcactt tgtgtgccct ctctgaggtc acagacctct ctcctgacat
4561 tgtacaggcc aactccctct tctccttcta tggagatgat gaaattgtga gcacagatat
4621 taaattggac ccagaaaaac tgacggggaa gttgagagaa tatggtctca aacctactcg
4681 tcctgacaaa actgagggcc ccctgattat cagtgaggat ctgaatggcc tgactttcct
4741 gagaagaacc gtcacccgtg accctgcagg gtggtttggc aaactggacc aaagctccat
4801 acttaggcaa ttgtattgga ccaagggccc caatcatgaa gacccctttg agtcaatgat
4861 tccacactcc cagagaccca tacaactcat gtcactcttg ggtgaggcgg cactgcatga
4921 accgtcattt tacagcaaga tcagcaagct tgtgatatct gaattgaaag aaggtggaat
4981 ggatttttac gtgcccaggc aagaacccat gtttaggtgg atgagattct cggatttgag
5041 cacgtgggag ggcgatcgca atcttgctcc cagtcttgtg aatgaagatg gcgtcgaatg
5101 acgccgctcc atctactgat ggtgcagccg gcctcgtgcc agaaagtaat actgaggtca
5161 tggctcttga acccgtggct ggtgccgctt tggcagcccc agtcactggt caaacaaata
5221 ttatagaccc ttggattaga gcaaattttg tccaggcccc caatggtgaa tttacagtct
5281 ccccccgtaa tgcccctggt gaagtgctac taaatctgga gttgggtcca gaattaaatc
5341 cttatctggc acacttagca agaatgtaca acgggtatgc cggtgggatg gaggtgcagg
5401 tcatgttggc tgggaacgcg ttcacagccg gcaagttggt cttcgccgcc gtgccacctc
5461 acttcccggt tgaaaacctt agtccacaac aaattaccat gttccctcat gtgattatag
5521 atgtgaggac tttggaacct gtcttattac cactccctga tgttagaaat aatttctttc
5581 attacaatca gaaggatgat cccaagatga gaattgtggc tatgctttat acccccctta
5641 gatcaaatgg ctcaggtgat gatgtgttca cagtctcctg tagggtgtta actaggccct
5701 cccctgactt tgacttcaca tatctggtgc caccaacagt ggagtctaaa acaaagccat
5761 tcaccctccc aatcctcaca cttggggaac tttccaattc cagattccca gtgtctatag
5821 accagatgta caccagccct aatgaagtta tatcagtgca gtgtcaaaat ggtaggtgca
5881 cattggacgg ggagctccaa gggacaacac aactccaggt cagtggcatt tgtgctttca
5941 agggagaggt aaccgcccac ttgcatgaca atgatcacct atacaatatc accatcacaa
6001 acttgaatgg atcccctttt gacccctctg aggacatccc tgcccctctg ggcgtacctg
6061 actttcaggg aagggtcttt ggtattatct cccaaaggga caaacacaat agccctggac
6121 ataatgaacc agcaaacagg ggacacgacg ctgtggtccc tacttacaca gcacagtata
6181 ctccaaaatt gggtcagatt caaattggca catggcagac tgacgatctc actgtcaacc
6241 aaccagtaaa attcacccca gttggactca atgatactga acattttaac caatgggtgg
6301 tccccagata tgctggtgcc ctaaacctca acacaaacct tgccccttct gttgccccag
6361 tatttccagg ggagcgcctg ctctttttca gatcatacat ccccctcaag ggtggctatg
6421 gaaatccagc cattgattgc ctactaccac aagagtgggt gcaacacttc taccaggaag
6481 cagccccttc tatgagtgag gtggcccttg tcaggtacat caacccggac actggtcggg
6541 cactgtttga ggccaagctc cacagagctg gtttcatgac ggtctcaagt aacaccagtg
6601 ccccggtggt tgtacctgtc aatggatact ttaggtttga ctcttgggtg aaccaatttt
6661 attctctcgc ccccatggga actggaaatg ggcgtagaag ggttcaataa tggctggagc
6721 ttttgtggct ggtcttgcag gggacgtgct cagtaatggg ctcagttcac taatcaatgc
6781 aggtgctaat gcaataaatc agagggcaga atttgatttt aatcagaaat tacagcaaaa
6841 ttcttttaat catgacaagg aaatgttgca ggctcagatt caggcaacta agcagctgca
6901 agcagacatg atggctataa agcagggggt cctgaccgct ggcggctttt cccccgctga
6961 tgcagccaga ggtgctgtga atgcgcccat gacacaagcg ctggattgga acggcacaag
7021 gtattgggca ccaggctcca tgaggaccac agcttactct gggagattca catcaaccgc
7081 cccagtaagg caggccgact ttcagcacac ccaaagccgg cccacgagtg gctcttctgt
7141 gtcctccttt gccactcagt cttcaagacc aactttgacc acaaccactg ggtcctcact
7201 tggtacagct tcatcaaatt cgactcgcag tacaaacctc tcccaatcaa cagtttccag
7261 agctgcatct aggactggtg agtgggttag agaccaaaac agaaatttgg aaccctatat
7321 gcatggtgcc ttacagacag cctttgtcac cccaccttcc agcagggcgt ctgacgggac
7381 agtctcaacc gtcccaaaag gtgttttgga ctcctggaca cctgcgttca acacccgcag
7441 gcagccgctt tttgcacacc tccgtaagag gggggagtca caagcttagt gaaaaggtga
7501 aaatctattt agaattaatt gatcttacc
//