Typing tool
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Typing tool
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Complete norovirus genomes
| MK764039 | GII.2 | |
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| GII.P2 |
ORF1: 4..5103
ORF2: 5084..6712
ORF3: 6712..7491
LOCUS MK764039 7512 bp RNA linear VRL 13-APR-2019
DEFINITION Norovirus GII isolate Hu/US/2016/GII.P2-GII.2/Cambria0298
nonstructural polyprotein (ORF1), VP1 (ORF2), and VP2 (ORF3) genes,
complete cds.
ACCESSION MK764039
VERSION MK764039.1
KEYWORDS .
SOURCE Norovirus GII
ORGANISM Norovirus GII
Viruses; Riboviria; Orthornavirae; Pisuviricota; Pisoniviricetes;
Picornavirales; Caliciviridae; Norovirus; Norwalk virus.
REFERENCE 1 (bases 1 to 7512)
AUTHORS Barclay,L., Cannon,J.L., Wikswo,M.E., Phillips,A., Browne,H.,
Montmayeur,A.M., Tatusov,R.L., Burke,R.M., Hall,A.J. and Vinje,J.
TITLE Emergence and characterization of multiple viruses associated with
a novel GII.P16 polymerase in the United States, 2015-2018
JOURNAL Unpublished
REFERENCE 2 (bases 1 to 7512)
AUTHORS Barclay,L., Cannon,J.L., Bryant,P., Montmayeur,A.M., Tatusov,R.L.,
Chhabra,P. and Vinje,J.
TITLE Direct Submission
JOURNAL Submitted (05-APR-2019) Division of Viral Diseases, Centers for
Disease Control and Prevention, 1600 Clifton Road NE, Atlanta, GA
30329, USA
COMMENT ##Assembly-Data-START##
Assembly Method :: Geneious v. R10; SPAdes v. 3.6
Sequencing Technology :: Illumina
##Assembly-Data-END##
FEATURES Location/Qualifiers
source 1..7512
/organism="Norovirus GII"
/mol_type="genomic RNA"
/strain="Cambria0298"
/isolate="Hu/US/2016/GII.P2-GII.2/Cambria0298"
/isolation_source="stool"
/host="Homo sapiens"
/db_xref="taxon:122929"
/country="USA"
/collection_date="24-Feb-2016"
/note="genotype: GII.P2-GII.2"
gene 4..5103
/gene="ORF1"
CDS 4..5103
/gene="ORF1"
/codon_start=1
/product="nonstructural polyprotein"
/protein_id="QBX92750.1"
/translation="MKMASNDASAAAAVNSNNDNTKSSSDGMLNNMAVTLKRALGARP
KQPAPREKPPRPPRPPTPELIKRIPPPPPNDGDEPTVMFSTVGGVSGLPELTTVGQPP
EANTAFSVPPLSQRENRDAKEPLTGTILEMWDGEIYHYGLYVERGLVLGVHKPPAAIS
IAKVELTPLSLYWRPVYTPQYLISPDSLRKLHGELFPYTAFENNCYAFCCWVLDLNDS
WLSRRMISRTTGFFRPYQEWNRKPLPTMDDSKLKKVANIVLCALSSLFTRPIKDIIGK
LKPLNILNILASCDWTFAGIVESLILLAELFDVFWTPPDVSAMIAPLLGDYELQGPED
IAVELVPVVMGGIGLVLGFTKEKIGKMLSSAASTLRACKDLGAYGLEILKLVMKWFFP
KKDEANELSMVRAIEDAVLDLEAIENNHMTTLLKDKNSLAAYMKTLDMEEEKARKLST
KSASPDIVGTINALLARIAAARSLVHRAKEELSSRPRPVVLMISGKPGIGKTHLAREL
AKKIASTLTGDQRVGLIPRNGVDHWDAYKGERVVLWDDYGMSNPIHDALRLQELADTC
PLTLNCDRIENKGKVFDSDAIIITTNLVNPAPLDYVNFEACSRRIDFLVYADAPEVEK
AKRDFPGQPDMWKDAYHSDFSHIKLQLAPQGGFDKNGNTPHGKGVMKTLTASSLIARA
SGLLHERLDEYELQGPPLSTFNFDRNKIAAFRQLAAENKYGLVDTMRVGNQLRNVTTM
DELKKAIKNIIIGKCQIVYGGNTYTLESDGKGKVVVERVQSTSVQINNEIAGAVHHLR
CARIRYYVKCVQEAIYSLLQIAGTVFVTSRIVSRMNIQNLWSRPLTEEADEATMKEGC
PKPREEEEFVVSSDDIKPEGKKGKNKSGRGKKHTAFSSKGLSDEEYEEYKRIREERNG
KYSIEEYLQDRDKYYEEVAIARATEEDFCEEEEVKIRQRIFRPTRKQRKEERANLGLV
TGSEIRKRNPDDFKPKGKLWADDDRSVDYNERISFEAPPSIWSRIVNFGSGWGFWVSP
SLFITSTHVIPQGITEAFGVPIRQVQIHKSGEFCRLRFPKPIRTDVSGMILEEGAPEG
TVATILIKRTTGELMPLAARMGTHATMRIQGRTVGGQMGMLLTGSNAKSMDLGTTPGD
CGCPYIYKRGNDYIVIGVHTAAARGGNTVICATQGSEGEATLEGGDNKGTYCGAPILG
PGNAPKLSTKTKFWRSSTTPLPPGTYEPAYLGGKDPRVKGGPSLQQVMRDQLKPFTEP
RGKPPKPSVLEAAKKTIINVLEQTIDPPQKWTYAQACASLDKTTSSGFPHHVRKNEHW
NGESFTGKLADQASKANLMFEEGKHMTPVYTAALKDELVKTEKVYGKIKKRLLWGSDL
ATMVRCARSFGGLMDELKAHCVTLPIRVGMNMNEDGPIVFEKHSRYRYHYDADYSRWD
STQQRAVLAAAMEIMVKFSAEPQLAQIVAEDLLSPSVVDVGDFKISINEGLPSGVPCT
SQWNSIAHWLLTLCALSEVTDLSPDIVQANSLFSFYGDDEIVSTDIKLDPEKLTGKLR
EYGLKPTRPDKTEGPLIISEDLNGLTFLRRTVTRDPAGWFGKLDQSSILRQLYWTKGP
NHEDPFESMIPHSQRPIQLMSLLGEAALHEPSFYSKISKLVISELKEGGMDFYVPRQE
PMFRWMRFSDLSTWEGDRNLAPSLVNEDGVE"
mat_peptide 4..993
/gene="ORF1"
/product="p48"
mat_peptide 994..2091
/gene="ORF1"
/product="NTPase"
mat_peptide 2092..2628
/gene="ORF1"
/product="p22"
mat_peptide 2629..3027
/gene="ORF1"
/product="VPg"
mat_peptide 3028..3570
/gene="ORF1"
/product="Pro"
mat_peptide 3571..5100
/gene="ORF1"
/product="RdRp"
gene 5084..6712
/gene="ORF2"
CDS 5084..6712
/gene="ORF2"
/note="major capsid protein"
/codon_start=1
/product="VP1"
/protein_id="QBX92751.1"
/translation="MKMASNDAAPSTDGAAGLVPESNTEVMALEPVAGAALAAPVTGQ
TNIIDPWIRANFVQAPNGEFTVSPRNAPGEVLLNLELGPELNPYLAHLARMYNGYAGG
MEVQVMLAGNAFTAGKLVFAAVPPHFPVENLSPQQITMFPHVIIDVRTLEPVLLPLPD
VRNNFFHYNQKDDPKMRIVAMLYTPLRSNGSGDDVFTVSCRVLTRPSPDFDFTYLVPP
TVESKTKPFTLPILTLGELSNSRFPVSIDQMYTSPNEVISVQCQNGRCTLDGELQGTT
QLQVSGICAFKGEVTAHLHDNDHLYNITITNLNGSPFDPSEDIPAPLGVPDFQGRVFG
IISQRDKHNSPGHNEPANRGHDAVVPTYTAQYTPKLGQIQIGTWQTDDLTVNQPVKFT
PVGLNDTEHFNQWVVPRYAGALNLNTNLAPSVAPVFPGERLLFFRSYIPLKGGYGNPA
IDCLLPQEWVQHFYQEAAPSMSEVALVRYINPDTGRALFEAKLHRAGFMTVSSNTSAP
VVVPVNGYFRFDSWVNQFYSLAPMGTGNGRRRVQ"
gene 6712..7491
/gene="ORF3"
CDS 6712..7491
/gene="ORF3"
/note="minor structural protein; small basic protein"
/codon_start=1
/product="VP2"
/protein_id="QBX92752.1"
/translation="MAGAFVAGLAGDVLSNGLSSLINAGANAINQRAEFDFNQKLQQN
SFNHDKEMLQAQIQATKQLQADMMAIKQGVLTAGGFSPADAARGAVNAPMTQALDWNG
TRYWAPGSMRTTAYSGRFTSTAPVRQADFQHTQSRPTSGSSVSSFATQSSRPTLTTTT
GSSLGTASSNSTRSTNLSQSTVSRAASRTGEWVRDQNRNLEPYMHGALQTAFVTPPSS
RASDGTVSTVPKGVLDSWTPAFNTRRQPLFAHLRKRGESQA"
ORIGIN
1 tgaatgaaga tggcgtctaa cgacgcttct gctgccgctg ctgttaacag caacaacgac
61 aacacaaaat cttcaagtga cggaatgctt aacaacatgg ccgtcaccct taaacgagcc
121 cttggggccc ggcccaaaca gccggccccg agggagaaac ccccaagacc ccctagacca
181 ccaacaccag aattgatcaa aagaatcccc cccccaccac ccaatgatgg ggacgaacca
241 accgtgatgt ttagcactgt aggtggcgtg tctggtctac ctgagctcac aacagttggc
301 caaccacctg aagctaacac ggcctttagt gtgcctcccc tcagccaaag ggagaatagg
361 gacgctaagg aaccgttaac tggaaccatt ctggaaatgt gggatgggga gatttatcat
421 tatggactgt atgtggaaag agggcttgtg ttaggcgtgc acaagccgcc ggctgccatc
481 agcatagcca aagtggagtt aacgcccctc tcactgtact ggagacctgt ttacacgcct
541 cagtacctta tatctcccga ctccttgagg aaactccatg gtgaattgtt tccctacaca
601 gcctttgaaa acaactgtta tgctttctgc tgttgggttt tggatcttaa cgattcatgg
661 ctaagcagga ggatgattag taggactact ggctttttca ggccctacca ggagtggaac
721 aggaagcccc tcccaactat ggatgactca aaattgaaga aggtcgcaaa catcgttctg
781 tgtgcattgt catcactgtt cactagaccc attaaggaca taattggcaa actcaaaccc
841 ctcaacatcc taaatatcct ggcctcatgt gactggacct ttgctggcat agtggagtca
901 ctaatcctct tggctgaact ctttgatgtg ttctggacac ccccagatgt gtctgcaatg
961 atcgcacccc tcctcggtga ctacgagctg caaggccccg aagacatcgc tgtggagctc
1021 gtgcccgttg ttatgggtgg gataggcttg gtgttgggat tcaccaaaga gaaaataggt
1081 aagatgctct cctctgcagc gtcaactctg agggcatgta aagatcttgg agcctacggg
1141 ttggagatcc taaaactagt catgaaatgg tttttcccaa agaaagatga ggccaacgaa
1201 ctgtctatgg ttagagccat tgaagacgct gtactagacc tggaggcaat tgagaacaac
1261 catatgacca ctctattgaa agacaagaac agccttgcag cctacatgaa gaccttggac
1321 atggaagagg aaaaagccag gaaactatcc accaagtcag cctcccctga cattgtgggc
1381 accataaacg ccctactggc taggatcgct gccgcacgtt ccttagttca tagggccaag
1441 gaggagctct ccagtagacc aagaccagtc gttctgatga tctctggcaa accagggata
1501 ggaaagaccc atctggccag agaattggca aagaaaattg catcaacact cacaggagac
1561 caaagggtgg gtcttatccc acggaatgga gttgaccatt gggacgccta caaaggtgag
1621 agagtggtgc tctgggatga ctacggtatg agcaatccca tccacgatgc actgaggttg
1681 caggaactgg cagacacatg tccactaact ctgaattgtg acaggattga aaacaagggg
1741 aaagtcttcg acagcgacgc gatcataatc actaccaatt tggtcaatcc cgcgccgctg
1801 gactatgtca actttgaggc ttgctccaga cgtatagact ttcttgtgta tgctgatgcc
1861 ccagaagtcg agaaagcaaa gcgggacttc cccggtcaac cggacatgtg gaaggacgcc
1921 tatcactctg atttctcaca tattaaattg caacttgcac cacaaggtgg gtttgacaaa
1981 aatggcaaca ccccacatgg taaaggagtg atgaagactc tcactgccag ttcactgatt
2041 gcgcgtgcct ctggtctctt gcacgagaga ttagatgagt acgagttaca gggtccgccc
2101 ctttcaacct tcaactttga ccgcaacaaa attgcagcgt tcagacaact cgccgctgaa
2161 aataagtatg gtttggtgga cacgatgagg gtgggcaacc agcttaggaa tgtcacgacc
2221 atggatgaac tcaagaaggc tatcaaaaac attataatcg ggaagtgcca gatagtctat
2281 ggcggcaaca cttacacgct tgagtctgac ggcaagggca aggttgttgt tgagagggtg
2341 cagagcacca gcgtgcaaat taacaatgag atcgctggtg cagtgcatca ccttagatgt
2401 gccaggataa ggtactatgt caaatgtgtc caagaggcca tctactcact cctccaaatc
2461 gccggcacgg tgtttgtcac ctcacgcatc gtaagccgca tgaacattca aaatttatgg
2521 tccagaccat taactgaaga agcagatgag gcaaccatga aagaggggtg ccctaaacct
2581 agggaagaag aggagtttgt cgtctcttcg gatgacatca agccagaggg caagaaaggt
2641 aagaacaaga gtggccgggg caagaaacac acggcatttt caagtaaagg tctcagtgat
2701 gaggagtatg aagagtacaa aaggatcaga gaggagagaa acggcaaata ctccatagag
2761 gaatacctac aggacagaga caaatactat gaagaggtgg ccattgccag ggcaactgaa
2821 gaagacttct gtgaagaaga agaggttaag attcgccaga ggatcttcag gccaacaaga
2881 aagcaacgca aggaagaaag agccaacctt ggcctcgtca ccggatctga gatcaggaag
2941 aggaatccag atgacttcaa accaaaagga aagctgtggg ccgacgatga caggagcgtc
3001 gactacaacg aaagaatcag ctttgaggcc ccaccgagca tttggtctag aattgttaac
3061 tttggttctg gatgggggtt ttgggtgtca cccagcctct tcataacatc aacacatgtc
3121 atacctcaag gtataactga ggcctttggt gtacccataa ggcaggttca aatacacaaa
3181 tcgggcgaat tctgtcgtct gagattccca aaacccatca ggacggatgt gtcaggtatg
3241 atactggagg agggagcgcc tgaaggcact gttgccacca tactcatcaa aagaaccact
3301 ggagagctga tgcctcttgc agcaagaatg ggcacccacg cgaccatgag aatacaagga
3361 cgcacggtgg gcggccagat ggggatgctg cttactgggt ccaacgcaaa gagcatggat
3421 cttggcacca cgcccggtga ctgtgggtgt ccctacattt acaaaagggg caacgactac
3481 atagtcattg gagtccacac agcagccgct cgtggcggaa acactgtcat ctgcgccaca
3541 caaggtagtg aaggtgaggc aacactcgag ggtggtgata ataaaggaac atactgtggg
3601 gcaccaatcc taggccccgg gaacgcccca aaactgagca ccaaaactaa gttctggagg
3661 tcctcaacta caccactccc acccggcacg tacgagccgg catatctggg aggaaaagac
3721 ccccgagtca aaggtggacc atctctgcaa caagttatgc gagaccaact gaagccattc
3781 actgaacccc gtggcaagcc accaaaacca agtgtccttg aagctgctaa aaagacaatc
3841 atcaatgtgc tagaacaaac aatagacccc ccacaaaaat ggacgtacgc gcaagcgtgc
3901 gcgtcccttg acaaaaccac atctagtggg ttcccccacc acgtgcgcaa gaacgagcac
3961 tggaatgggg aatctttcac aggaaaattg gctgaccagg catcaaaagc aaacttaatg
4021 tttgaagagg ggaagcacat gactccagtt tacacagctg cccttaagga tgagctggtc
4081 aaaactgaga aggtgtatgg aaaaataaag aagaggttgc tttggggctc tgacctggcc
4141 accatggtgc ggtgcgcgcg ctcctttggc ggtctgatgg acgaactcaa agcccactgt
4201 gtgacacttc cgataagggt tggcatgaac atgaatgaag atggaccaat agtctttgag
4261 aaacattcca gatataggta tcactatgat gcagactatt ccaggtggga ctcaacacag
4321 caaagagccg ttctggccgc ggccatggag atcatggtta aattctcagc agaaccacaa
4381 ctagcccaaa tagttgcaga ggatctattg tcgcctagtg tagttgacgt gggcgacttc
4441 aaaatttcca tcaatgaagg gttgccatcg ggtgtccctt gcacctctca gtggaattcc
4501 atcgcacatt ggctcctcac tttgtgtgcc ctctctgagg tcacagacct ctctcctgac
4561 attgtacagg ccaactccct cttctccttc tatggagatg atgaaattgt gagcacagat
4621 attaaattgg acccagaaaa actgacgggg aagttgagag aatatggtct caaacctact
4681 cgtcctgaca aaactgaggg ccccctgatt atcagtgagg atctgaatgg cctgactttc
4741 ctgagaagaa ccgtcacccg tgaccctgca gggtggtttg gcaaactgga ccaaagctcc
4801 atacttaggc aattgtattg gaccaagggc cccaatcatg aagacccctt tgagtcaatg
4861 attccacact cccagagacc catacaactc atgtcactct tgggtgaggc ggcactgcat
4921 gaaccgtcat tttacagcaa gatcagcaag cttgtgatat ctgaattgaa agaaggtgga
4981 atggattttt acgtgcccag gcaagaaccc atgtttaggt ggatgagatt ctcggatttg
5041 agcacgtggg agggcgatcg caatcttgct cccagtcttg tgaatgaaga tggcgtcgaa
5101 tgacgccgct ccatctactg atggtgcagc cggcctcgtg ccagaaagta atactgaggt
5161 catggctctt gaacccgtgg ctggtgccgc tttggcagcc ccagtcactg gtcaaacaaa
5221 tattatagac ccttggatta gagcaaattt tgtccaggcc cccaatggtg aatttacagt
5281 ctccccccgt aatgcccctg gtgaagtgct actaaatctg gagttgggtc cagaattaaa
5341 tccttatctg gcacacttag caagaatgta caacgggtat gccggtggga tggaggtgca
5401 ggtcatgttg gctgggaacg cgttcacagc cggcaagttg gtcttcgccg ccgtgccacc
5461 tcacttcccg gttgaaaacc ttagtccaca acaaattacc atgttccctc atgtgattat
5521 agatgtgagg actttggaac ctgtcttatt accactccct gatgttagaa ataatttctt
5581 tcattacaat cagaaggatg atcccaagat gagaattgtg gctatgcttt atacccccct
5641 tagatcaaat ggctcaggtg atgatgtgtt cacagtctcc tgtagggtgt taactaggcc
5701 ctcccctgac tttgacttca catatctggt gccaccaaca gtggagtcta aaacaaagcc
5761 attcaccctc ccaatcctca cacttgggga actttccaat tccagattcc cagtgtctat
5821 agaccagatg tacaccagcc ctaatgaagt tatatcagtg cagtgtcaaa atggtaggtg
5881 cacattggac ggggagctcc aagggacaac acaactccag gtcagtggca tttgtgcttt
5941 caagggagag gtaaccgccc acttgcatga caatgatcac ctatacaata tcaccatcac
6001 aaacttgaat ggatcccctt ttgacccctc tgaggacatc cctgcccctc tgggcgtacc
6061 tgactttcag ggaagggtct ttggtattat ctcccaaagg gacaaacaca atagccctgg
6121 acataatgaa ccagcaaaca ggggacacga cgctgtggtc cctacttaca cagcacagta
6181 tactccaaaa ttgggtcaga ttcaaattgg cacatggcag actgacgatc tcactgtcaa
6241 ccaaccagta aaattcaccc cagttggact caatgatact gaacatttta accaatgggt
6301 ggtccccaga tatgctggtg ccctaaacct caacacaaac cttgcccctt ctgttgcccc
6361 agtatttcca ggggagcgcc tgctcttttt cagatcatac atccccctca agggtggcta
6421 tggaaatcca gccattgatt gcctactacc acaagagtgg gtgcaacact tctaccagga
6481 agcagcccct tctatgagtg aggtggccct tgtcaggtac atcaacccgg acactggtcg
6541 ggcactgttt gaggccaagc tccacagagc tggtttcatg acggtctcaa gtaacaccag
6601 tgccccggtg gttgtacctg tcaatggata ctttaggttt gactcttggg tgaaccaatt
6661 ttattctctc gcccccatgg gaactggaaa tgggcgtaga agggttcaat aatggctgga
6721 gcttttgtgg ctggtcttgc aggggacgtg ctcagtaatg ggctcagttc actaatcaat
6781 gcaggtgcta atgcaataaa tcagagggca gaatttgatt ttaatcagaa attacagcaa
6841 aattctttta atcatgacaa ggaaatgttg caggctcaga ttcaggcaac taagcagctg
6901 caagcagaca tgatggctat aaagcagggg gtcctgaccg ctggcggctt ttcccccgct
6961 gatgcagcca gaggtgctgt gaatgcgccc atgacacaag cgctggattg gaacggcaca
7021 aggtattggg caccaggctc catgaggacc acagcttact ctgggagatt cacatcaacc
7081 gccccagtaa ggcaggccga ctttcagcac acccaaagcc ggcccacgag tggctcttct
7141 gtgtcctcct ttgccactca gtcttcaaga ccaactttga ccacaaccac tgggtcctca
7201 cttggtacag cttcatcaaa ttcgactcgc agtacaaacc tctcccaatc aacagtttcc
7261 agagctgcat ctaggactgg tgagtgggtt agagaccaaa acagaaattt ggaaccctat
7321 atgcatggtg ccttacagac agcctttgtc accccacctt ccagcagggc gtctgacggg
7381 acagtctcaa ccgtcccaaa aggtgttttg gactcctgga cacctgcgtt caacacccgc
7441 aggcagccgc tttttgcaca cctccgtaag aggggggagt cacaagctta gtgaaaaggt
7501 gaaaatctat tt
//