Typing tool
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Typing tool
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Complete norovirus genomes
| MK764022 | GII.2 | |
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| GII.P16 |
ORF1: 2..5101
ORF2: 5082..6710
ORF3: 6710..7489
LOCUS MK764022 7533 bp RNA linear VRL 13-APR-2019
DEFINITION Norovirus GII isolate Hu/US/2018/GII.P16-GII.2/Hanover0423
nonstructural polyprotein (ORF1), VP1 (ORF2), and VP2 (ORF3) genes,
complete cds.
ACCESSION MK764022
VERSION MK764022.1
KEYWORDS .
SOURCE Norovirus GII
ORGANISM Norovirus GII
Viruses; Riboviria; Orthornavirae; Pisuviricota; Pisoniviricetes;
Picornavirales; Caliciviridae; Norovirus; Norwalk virus.
REFERENCE 1 (bases 1 to 7533)
AUTHORS Barclay,L., Cannon,J.L., Wikswo,M.E., Phillips,A., Browne,H.,
Montmayeur,A.M., Tatusov,R.L., Burke,R.M., Hall,A.J. and Vinje,J.
TITLE Emergence and characterization of multiple viruses associated with
a novel GII.P16 polymerase in the United States, 2015-2018
JOURNAL Unpublished
REFERENCE 2 (bases 1 to 7533)
AUTHORS Barclay,L., Cannon,J.L., Dickinson,M.K., Montmayeur,A.M.,
Tatusov,R.L., Chhabra,P. and Vinje,J.
TITLE Direct Submission
JOURNAL Submitted (05-APR-2019) Division of Viral Diseases, Centers for
Disease Control and Prevention, 1600 Clifton Road NE, Atlanta, GA
30329, USA
COMMENT ##Assembly-Data-START##
Assembly Method :: Geneious v. R10; SPAdes v. 3.6
Sequencing Technology :: Illumina
##Assembly-Data-END##
FEATURES Location/Qualifiers
source 1..7533
/organism="Norovirus GII"
/mol_type="genomic RNA"
/strain="Hanover0423"
/isolate="Hu/US/2018/GII.P16-GII.2/Hanover0423"
/isolation_source="stool"
/host="Homo sapiens"
/db_xref="taxon:122929"
/country="USA"
/collection_date="06-Feb-2018"
/note="genotype: GII.P16-GII.2"
gene 2..5101
/gene="ORF1"
CDS 2..5101
/gene="ORF1"
/codon_start=1
/product="nonstructural polyprotein"
/protein_id="QBX92745.1"
/translation="MKMASNDATVAVACNNNNDKEKSSGEGLFTNMSSTLKKALGARP
KQPAPRDKPQKPPRPPTPELVKRIPPPPPNGEEEEEPVIRYEVKSGISGLPELTTVPQ
PDVANTAFSVPPLSLRENKEAKEPLTGAILEMWDGEIYHYGLYVEKGLVLGVHKPPAA
ISMARVELTPLSLYWRVVYTPQYLISPETLRRLNGEAFPYTAFDNNCYAFCCWVLDLN
DSWLSRRMVQRTTGFFRPYQEWNRKPLPTMDDSKIKKVANIFLCSLSTLFTRPIKDLI
GKIKPLNILNILATCDWTFAGVVESLILLAELFGVFWTPPDVSAMIAPLLGDYELQGP
EDLAVELVPVVMGGIGLVLGFTKEKIGKMLSSAASTLRACKDLGAYGLEILKLVMKWF
FPKKEEANELAMVRAIEDAVLDLEAIENNHMTTLLKDKDSLATYMKTLDMEEEKARRL
STKSASPDIVGTINALLARIAAARSLVHRAKEELSSRIRPVVIMISGKPGIGKTHLAR
EVARKVASTLTGDQRVGLIPRNGVDHWDAYKGERVVLWDDYGMSNPIHDALRIQELAD
TCPLTLNCDRIENKGKVFDSEVIIITTNLANPAPLDYVNFEACSRRIDFLVYAEAPEV
EKAKRDFPGQPDMWKDTFKPDFSHIKLQLAPQGGFDKNGNTPHGKGVMKTLTTGSLIA
RASGLLHERMDEFELQGPTITTFNFDRNKITAFRQLAAENKYGLVDTMKVGNQLKGVK
TMEELKQAIRNVTIKRCQIIYGGSTYDLESDGKGKVLVEKVKNTSVQTNNELAGALHH
LKHARIRYYVKCVQEVVYSIIQIAGAAFVTTRIARRMNIQELWSKPQLDQNESETKEE
APKSEDDEFIISSKDIKEEGKKGKNKTGRGKKHTAFSSKGLSDEEYDEYKRIREERNG
KYSIEEYLQDRDRYYEELAIAKATEEDFCEEEEIKIRQRIFRPTRKQRKEERATLGLV
TGSEIRKRNPDDFKPKGKLWADDNRSVDYNEKLDFEAPPSIWSRIVSFGSGWGFWVSP
SLFITSTHVIPAGITEAFGVPIKQIQIHKSGEFCRFRFPKPIRPDVTGMILEEGAPEG
TVATVLIKRPTGELMPLAARMGTHATMKIQGRMVGGQMGMLLTGSNAKGMDLGTTPGD
CGCPYIYKRGNDYIVIGVHTAAARGGNTVICATQGSEGEATLEGGDDKGTYCGAPILG
PGGAPKLSTKTKFWRSSNTPLPPGTYEPAYLGGRDPRVKGGPSLQQVMRDQLKPFTEP
RGKPPRPSVLEAAKQTIINVLEQTLDPPQKWTYAQACASLDKTTSSGHPHHVRKNEFW
NGETFTGKLADQASKANLMFEEGKHMTPVYTAALKDELVKTEKIYGKIKKRLLWGSDL
STMIRCARSFGGLMDEMKAHCISLPVRVGMNMNEDGPIIFEKHSRYKYHYDADYSRWD
STQQRAVLAAALEIMVRFSAEPQLAQIVAEDLLAPSVVDVGDFKITINEGLPSGVPCT
SQWNSIAHWLLTLCALSEVTKLSPDIIQANSMFSFYGDDEIVSTDIKLDPEQLTAKLK
EYGLKPTRPDKTEGPLIISEDLNGLTFLRRTVTRDPAGWFGKLDQSSILRQMYWTRGP
NHEDPNETMIPHSQRPIQLMALLGEASLHGPSFYSKISKLVITELKEGGMDFYVPRQE
PMFRWMRFSDLSTWEGDRNLAPNFVNEDGVE"
mat_peptide 2..997
/gene="ORF1"
/product="p48"
mat_peptide 998..2095
/gene="ORF1"
/product="NTPase"
mat_peptide 2096..2626
/gene="ORF1"
/product="p22"
mat_peptide 2627..3025
/gene="ORF1"
/product="VPg"
mat_peptide 3026..3568
/gene="ORF1"
/product="Pro"
mat_peptide 3569..5098
/gene="ORF1"
/product="RdRp"
gene 5082..6710
/gene="ORF2"
CDS 5082..6710
/gene="ORF2"
/note="major capsid protein"
/codon_start=1
/product="VP1"
/protein_id="QBX92746.1"
/translation="MKMASNDAAPSTDGAAGLVPESNNEVMALEPVAGAALAAPVTGQ
TNIIDPWIRANFVQAPNGEFTVSPRNAPGEVLLNLELGPELNPYLAHLARMYNGYAGG
MEVQVMLAGNAFTAGKLVFAAVPPHFPVENLSPQQITMFPHVIIDVRTLEPVLLPLPD
VRNNFFHYNQKDDPKMRIVAMLYTPLRSNGSGDDVFTVSCRVLTRPSPDFDFTYLVPP
TVESKTKPFTLPILTLGELSNSRFPVSIDQMYTSPNEIISVQCQNGRCTLDGELQGTT
QLQVSGICAFKGEVTAHLHDNDHLYNVTITNLNGSPFDPSEDIPAPLGVPDFQGRVFG
IISQRDKHNSPGHNEPANRGHDAVVPTYTAQYTPKLGQIQIGTWQTDDLTVNQPVKFT
PVGLNDTEHFNQWVVPRYAGALNLNTNLAPSVAPVFPGERLLFFRSYIPLKGGYGNPA
IDCLLPQEWVQHFYQEAAPSMSEVALVRYINPDTGRALFEAKLHRAGFMTVSSNTSAP
VVVPANGYFRFDSWVNQFYSLAPMGTGNGRRRVQ"
gene 6710..7489
/gene="ORF3"
CDS 6710..7489
/gene="ORF3"
/note="minor structural protein; small basic protein"
/codon_start=1
/product="VP2"
/protein_id="QBX92747.1"
/translation="MAGAFVAGLAGDVLSNGLSSLINAGANAINQRAEFDFNQKLQQN
SFNHDKEMLQAQIQATKQLQADMMAIKQGVLTAGGFSPADAARGAVNAPMTQALDWNG
TRYWAPNSMRTTSYSGKFTSTAPVRQADFQHTQSRPSSGSSVSSFATQSSRPTLTTTT
GSSHGTASSNSTRSTSLSQSTVSRATSRTGEWVRDQNKNLEPYMHGALQTAFVTPPSS
RASDGTVSTVPKGVLDSWTPAFNTRRQPLFAHLRKRGESQA"
ORIGIN
1 aatgaagatg gcgtctaacg acgctaccgt tgccgttgct tgcaacaaca acaacgacaa
61 agaaaaatct tcaggtgaag gcttattcac aaatatgtct tccaccttaa agaaagccct
121 cggggctagg cccaaacagc ctgccccgag agacaaacca caaaagcccc caagaccacc
181 aactcccgag ttggtcaaga ggataccccc tcctccacct aacggcgaag aagaagaaga
241 accagtcatt aggtatgagg tcaagagtgg gatctctggc ctgcccgagc tcacaacagt
301 cccccagccg gacgtggcca acacagcatt cagtgttcca ccactgagct tgagagaaaa
361 caaggaggcc aaggagccac taacaggggc aatactagag atgtgggatg gagagatata
421 ccactatggc ctgtacgtgg agaaaggctt agtgttgggt gtgcacaaac cacctgcagc
481 cataagtatg gcaagagtgg agctgacgcc gttgtcattg tactggcgtg tggtgtacac
541 tccccaatac ctcatctccc ctgaaaccct caggaggctc aacggagagg cgttccctta
601 caccgccttt gacaacaact gctatgcctt ttgctgctgg gtgttagacc tcaatgactc
661 atggcttagc aggaggatgg tacaaagaac aacgggcttc ttcagacctt accaagagtg
721 gaacagaaaa cccctgccta ccatggatga ctccaaaatt aagaaggtag caaatatatt
781 cctatgttca ttgtccacat tattcaccag acccataaaa gacctcatag gaaaaattaa
841 accattgaac atattgaata tcctggcaac gtgtgactgg acttttgccg gagtagtgga
901 gtctctgata ttacttgctg aactcttcgg agttttctgg acacccccag atgtgtctgc
961 tatgatcgct cccttactcg gggactacga gttgcaaggg ccagaagacc tcgccgttga
1021 actcgtgccc gtggtaatgg gggggattgg tttggtgttg ggattcacca aagagaaaat
1081 tggcaaaatg ttgtcctcag cagcatcaac actcagggct tgcaaagatc ttggtgccta
1141 tggtttagag atactcaaat tggtcatgaa gtggttcttc ccaaagaaag aggaggccaa
1201 tgagctagct atggtgaggg ccatagagga tgctgtatta gaccttgagg caatagaaaa
1261 taaccacatg acaaccctgt tgaaagacaa agacagctta gcaacataca tgaaaacact
1321 ggacatggag gaggagaaag ccaggaggtt gtccacaaaa tctgcatccc ctgacatagt
1381 tgggacaatc aacgccctgc tggctcgaat agcagcggcc aggtcattag tccacagggc
1441 caaggaagag ctatctagta ggataaggcc agtagttatt atgatatctg gcaagccagg
1501 aataggcaaa actcatctgg ccagggaggt ggcaagaaag gtggcatcca ctctcacagg
1561 agatcaaaga gtcggactca taccacgaaa cggtgtggac cattgggatg catacaaagg
1621 tgagagagtc gtgctgtggg acgactatgg catgagtaac cctattcatg atgctcttcg
1681 catacaagaa ttggctgata cgtgtcccct taccttaaat tgtgacagaa ttgaaaataa
1741 ggggaaagtt ttcgacagtg aagtcataat aattacaaca aaccttgcca atccagcccc
1801 acttgattac gtcaactttg aggcctgttc caggagaatt gatttcctgg tgtacgctga
1861 ggcaccagaa gtagaaaagg caaaacggga ctttcctggt cagccagata tgtggaagga
1921 caccttcaag ccggactttt cacacatcaa gctacagctt gcaccccagg gcggctttga
1981 caagaatggc aacaccccac atgggaaagg agtgatgaag accctcacta ccggttctct
2041 gattgcccgt gcatcaggcc tactgcatga gaggatggat gaatttgaac tccaaggccc
2101 cacaatcacc acctttaatt tcgaccgaaa caaaatcacg gcattcagac aattggctgc
2161 agaaaacaag tatggattgg tggataccat gaaagttggc aatcaattaa aaggagtgaa
2221 aaccatggaa gaactcaaac aagcaatcag gaatgtgacc atcaagaggt gccagatcat
2281 ctacggtggt tccacgtatg accttgaatc tgatggcaag ggcaaagttt tggtggaaaa
2341 ggtcaagaac acctctgtac agaccaataa cgagttggct ggggccctgc accatctcaa
2401 acatgcccga atcaggtact atgtcaaatg tgtgcaagaa gtagtctatt ccatcataca
2461 aattgccggc gctgcgtttg tcaccacgcg catcgcacgc cgcatgaaca tacaagaact
2521 ctggtcgaag ccacaactag atcaaaatga atcagagact aaggaagagg cccccaagtc
2581 agaagatgac gagttcatca tatcttctaa ggacatcaag gaggaaggaa agaagggcaa
2641 aaacaaaact ggccgtggca agaaacacac tgcattctcc agcaagggct tgagcgatga
2701 ggagtatgac gagtacaaga gaataagaga agagagaaat gggaagtact ctatagagga
2761 gtatcttcaa gacagagaca ggtactatga ggagctcgcc attgccaaag ccacggaaga
2821 agacttctgt gaggaggagg agatcaaaat ccgtcagaga attttccgtc ccaccaggaa
2881 acaaagaaag gaagagaggg ccacattagg gctagtaaca ggttcagaaa tcagaaaaag
2941 aaaccctgat gacttcaaac ccaaagggaa gctgtgggcc gatgacaata ggagtgttga
3001 ctacaatgag aaactggact ttgaggcccc cccaagcata tggtctagga ttgtgagctt
3061 tggctctggc tggggcttct gggtgtcacc aagccttttc ataacatcaa ctcatgtaat
3121 ccccgcaggc ataacagaag cgtttggagt ccccatcaaa caaattcaga tccacaaatc
3181 aggcgaattt tgccgattca gattcccaaa accaattaga ccagatgtga caggaatgat
3241 cttggaagaa ggtgcgcctg agggcaccgt ggcaactgtg ctcatcaaac gccccaccgg
3301 agagctcatg cctcttgcag ccagaatggg aacacacgca accatgaaaa ttcaaggccg
3361 catggttggc ggacagatgg gtatgttgct cactggatca aatgctaaag gaatggactt
3421 gggaacaact cctggtgact gtggctgtcc ttacatctat aaaaggggca atgactatat
3481 agtcattggg gtgcacactg cagcagcccg tggtggaaac actgtcatct gtgccacaca
3541 gggaagtgag ggtgaggcaa ctcttgaggg tggagatgac aaaggaacat actgtggggc
3601 acccattcta ggccctgggg gtgcaccaaa attgagcacc aaaaccaaat tttggaggtc
3661 atcgaacacg cccctcccac cagggacata tgagcctgcc tacctcggtg gccgtgatcc
3721 gcgtgttaag ggtgggcctt ccctgcagca ggtgatgaga gaccagttga agccattcac
3781 tgaacccagg ggcaaacctc caagaccaag tgtattggaa gcagccaaac aaaccatcat
3841 taatgtcctc gaacaaaccc tggaccctcc acaaaaatgg acatacgcac aggcgtgcgc
3901 ctcacttgac aaaaccacct ccagcgggca cccccatcac gtccgaaaga atgaattctg
3961 gaatggtgag accttcactg gtaaactggc agaccaagca tcaaaagcaa acctaatgtt
4021 tgaggaaggg aaacacatga caccagtgta cacagcggca ctcaaggacg agctagtcaa
4081 gactgagaaa atttatggaa agatcaagaa gagactgctc tggggctctg acttgtccac
4141 catgatccgg tgcgctaggt catttggtgg gcttatggac gagatgaagg cacactgcat
4201 atcactccca gtccgagttg gcatgaatat gaatgaagat ggcccaataa tatttgagaa
4261 acattccaga tacaaatatc actatgatgc agactactct cgttgggatt caacacaaca
4321 gagggcagtt ctagcagcag ccttggaaat catggtcaga ttctctgcag aaccacaatt
4381 ggcacaaata gtcgctgagg atctgctggc ccctagtgta gtagatgtag gagactttaa
4441 aatcacaata aatgaagggc tcccttctgg tgtgccatgc acttctcaat ggaactccat
4501 cgcacactgg ctgctaactc tctgtgcctt gtctgaagtc accaaactat cccctgacat
4561 tatacaggca aattccatgt tctcatttta cggtgatgac gagattgtca gtaccgacat
4621 aaaattggac cctgaacagt taaccgccaa attgaaggag tacggcctga aaccaacccg
4681 cccagacaaa accgagggac ccctgattat cagtgaagat ttgaacggtc tcactttcct
4741 ccgaaggacg gtgactcgtg acccagctgg ctggtttgga aaactggacc aaagctcaat
4801 tttgaggcag atgtactgga ctagaggacc aaatcatgaa gaccccaatg agacaatgat
4861 accccattcc caaagaccca tacagctcat ggcactgctt ggtgaagcct ctcttcacgg
4921 accctctttc tacagtaaaa tcagtaaatt ggtcataact gaactcaaag aaggtgggat
4981 ggacttttac gtgccaaggc aggaacccat gttcaggtgg atgaggtttt ctgacttgag
5041 cacgtgggag ggcgatcgca atctggctcc caattttgtg aatgaagatg gcgtcgaatg
5101 acgccgctcc atctactgat ggtgcagccg gcctcgtgcc agaaagtaac aatgaggtca
5161 tggctcttga acccgtggct ggtgccgcct tggcagcccc ggtcaccggt caaacaaata
5221 ttatagaccc ttggattaga gcaaattttg tccaggcccc caatggtgaa tttacagtct
5281 ccccccgaaa tgcccctggt gaagtgctac tgaatctaga gttgggtcca gaattaaatc
5341 cttatctggc acatttagca agaatgtaca atgggtatgc cggtgggatg gaggtgcagg
5401 tcatgttggc tgggaacgcg ttcacagccg gcaagttggt cttcgccgcc gtgccacccc
5461 acttcccggt tgaaaacctt agcccacagc aaatcaccat gttccctcat gtgatcatag
5521 atgtgagaac cttggaacct gttttattac cactccctga tgttaggaat aacttcttcc
5581 attataacca gaaagatgac cccaagatga gaattgtggc tatgctttat acccccctca
5641 ggtctaatgg ttcaggtgat gatgtgttta cagtctcctg tagggtgttg actagacctt
5701 cccctgactt tgacttcaca tacctggtgc caccaacagt ggagtctaaa acaaagccat
5761 tcaccctccc aatcctcaca cttggggaac tttccaattc taggttccca gtgtccatag
5821 accagatgta caccagccct aatgaaatta tatcagtgca gtgtcaaaat ggtaggtgca
5881 cactggacgg ggagctccaa gggacaactc aactccaagt cagtggcatt tgtgctttca
5941 aaggtgaagt gaccgcccac ttgcatgaca atgatcacct atataatgtc accatcacaa
6001 acttgaatgg gtcccctttt gatccctccg aggatatccc tgcccctttg ggtgtgcctg
6061 acttccaggg aagggttttt ggtatcatct cccaaagaga taaacacaat agtcctgggc
6121 ataatgaacc agcaaacagg ggacacgacg ctgtggtccc tacttacaca gcacagtaca
6181 ctccaaaact tggacaaatt caaattggca catggcaaac tgacgacctt acagtcaacc
6241 agccagtcaa attcacccca gttggactca atgacactga acactttaac caatgggtgg
6301 tccctaggta tgctggtgcc ctaaacctca atacaaacct tgccccttct gttgctccag
6361 tatttccagg agagcgcctg ctcttcttca gatcatacat tcccctcaag ggcggttatg
6421 gaaacccagc cattgattgc ctactaccac aagagtgggt gcagcacttc tatcaggaag
6481 cagccccttc aatgagtgag gtggccctcg tcagatacat caacccggac actggtcggg
6541 cactgtttga ggccaagctc cacagagctg gtttcatgac agtctcgagc aacaccagtg
6601 ccccggtggt tgtgcctgcc aacgggtact tcagatttga ttcttgggtg aaccaatttt
6661 actctctcgc ccccatggga actgggaatg ggcgtagaag ggttcaataa tggctggagc
6721 ttttgtagct ggtcttgcag gggacgtgct cagcaatggg cttagttcat taatcaatgc
6781 aggtgctaat gcaataaatc agagggcaga atttgatttt aatcaaaaat tgcagcaaaa
6841 ttcttttaat catgataagg agatgttgca ggctcagatt caggcaacta agcagctgca
6901 ggcagacatg atggctataa aacaaggggt cttgaccgct ggcggctttt cccctgctga
6961 tgcagccaga ggtgctgtga acgcgcccat gacacaggcg ctggattgga atggcacaag
7021 gtattgggct ccaaactcca tgaggaccac atcttattct ggaaaattca catcaaccgc
7081 cccagtgagg caggctgact tccagcacac ccaaagccgg ccttcgagtg gctcctctgt
7141 gtcctccttt gccactcagt cttcaaggcc aactctgacc acaaccactg gttcctcaca
7201 tggcacagcc tcatcaaatt caactcgcag cacaagcctc tcccaatcaa cggtctccag
7261 agctacatct agaactggtg agtgggttag agatcaaaat aaaaatttgg aaccctacat
7321 gcatggtgcc ttacagacag cctttgtcac cccaccttcc agcagggcat ctgacggaac
7381 agtctcaacc gtccctaaag gtgttttgga ctcctggaca cctgcgttca acacccgcag
7441 gcagccgctt tttgcacacc tccgtaagag gggggagtca caagcttagt gaaaaggtga
7501 aaatttattt aggattaatt gattttacct ttt
//