Typing tool
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Typing tool
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Complete norovirus genomes
| MK764020 | GII.3 | |
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| GII.P16 |
ORF1: 1..5049
ORF2: 5030..6676
ORF3: 6676..7440
LOCUS MK764020 7478 bp RNA linear VRL 13-APR-2019
DEFINITION Norovirus GII isolate Hu/US/2014/GII.P16-GII.3/Pittsylvania0388
nonstructural polyprotein (ORF1) gene, partial cds; and VP1 (ORF2)
and VP2 (ORF3) genes, complete cds.
ACCESSION MK764020
VERSION MK764020.1
KEYWORDS .
SOURCE Norovirus GII
ORGANISM Norovirus GII
Viruses; Riboviria; Orthornavirae; Pisuviricota; Pisoniviricetes;
Picornavirales; Caliciviridae; Norovirus; Norwalk virus.
REFERENCE 1 (bases 1 to 7478)
AUTHORS Barclay,L., Cannon,J.L., Wikswo,M.E., Phillips,A., Browne,H.,
Montmayeur,A.M., Tatusov,R.L., Burke,R.M., Hall,A.J. and Vinje,J.
TITLE Emergence and characterization of multiple viruses associated with
a novel GII.P16 polymerase in the United States, 2015-2018
JOURNAL Unpublished
REFERENCE 2 (bases 1 to 7478)
AUTHORS Barclay,L., Cannon,J.L., Dickinson,M.K., Montmayeur,A.M.,
Tatusov,R.L., Chhabra,P. and Vinje,J.
TITLE Direct Submission
JOURNAL Submitted (05-APR-2019) Division of Viral Diseases, Centers for
Disease Control and Prevention, 1600 Clifton Road NE, Atlanta, GA
30329, USA
COMMENT ##Assembly-Data-START##
Assembly Method :: Geneious v. R10; SPAdes v. 3.6
Sequencing Technology :: Illumina
##Assembly-Data-END##
FEATURES Location/Qualifiers
source 1..7478
/organism="Norovirus GII"
/mol_type="genomic RNA"
/strain="Pittsylvania0388"
/isolate="Hu/US/2014/GII.P16-GII.3/Pittsylvania0388"
/isolation_source="stool"
/host="Homo sapiens"
/db_xref="taxon:122929"
/country="USA"
/collection_date="05-Mar-2014"
/note="genotype: GII.P16-GII.3"
gene <1..5049
/gene="ORF1"
CDS <1..5049
/gene="ORF1"
/codon_start=1
/product="nonstructural polyprotein"
/protein_id="QBX92739.1"
/translation="NNDKEKSSGEGLFTNMSSTLKKALGARPKQPAPRDNPQKPPRSP
TPELVKGIPPPPPNGEEEEPVIRYEVKSGISGLPELTTVPQPDVANTAFSVPPLSLRE
NREAKEPLTGAILEMWDGEIYHYGLYVEKGLVLGVHKPPAAISMAKVELTPLSLYWRV
VYTPQYLISPETLRRLNGEAFPYTAFDNNCYAFCCWVLDLNDSWLNRRMVQRTTGFFR
PYQEWNRKPLPTMDDSKIKKVANIFLCSLSTLFTRPIKDLIGKIKPLNILNILATCDW
TFAGIVESLILLAELFGVFWTPPDVSAMIAPLLGDYELQGPEDLAVELVPVVMGGVGL
VLGFTKEKIGKMLSSAASTLRACKDLGAYGLEILKLVMKWFFPKKEEANELAMVRAIE
DAVLDLEAIENNHMTTLLKDKDSLATYMKTLDMEEEKARRLSTKSASPDIVGTINALL
ARIAAARSLVHRAKEELSSRMRPVVVMISGKPGIGKTHLAREVARKVASTLTGDQRVG
LIPRNGVDHWDAYKGERVVLWDDYGMSNPIQDALRIQELADTCPLTLNCDRIENKGKV
FDSEVIIITTNLANPAPLDYVNFEACSRRIDFLVYAEAPEVEKAKRDFPGQPDMWKDA
FKSDFSHIRLQLAPQGGFDKNGNTPHGKGVMKTLTTGSLIARASGLLHERMDEFELQG
PTITTFNFDRNRITAFRQLAAENKYGLVDTMRVGNQLKGVKTMEELKQAIKNVIIKRC
RIIYGGSTYDLESDGKGKVLVEKVKNTSVQTNNELAGALHHLKHARIRYYVRCVQEAV
YSIIQIAGAAFVTTRIARRMNIQELWSKPPLDQNELEAKEEAPKSEDGEFIISSKDIK
EEGKKGKNKTGRGKKHTAFSSKGLSDEEYDEYKRIREERNGKYSIEEYLQDRDRYYEE
LAIAKATEEDFCEEEEIKIRQRIFRPTRKQRKEERATLGLVTGSEIRKRNPDDFKPKG
KLWADDNRSVDYNEKLDFEAPPSIWSRIVSFGSGWGFWVSPSLFITSTHVIPAGITEA
FGVPIKQIQVHKSGEFCRFRFPKPIRPDVTGMILEEGAPEGTVATVLIKRPTGELMPL
AARMGTHATMKIQGRMVGGQMGMLLTGSNAKGMDLGTTPGDCGCPYIYKRGNDYIVIG
VHTAAARGGNTVICATQGSEGEATLEGGDDKGTYCGAPILGPGGAPKLSTKTKFWRSS
NTPLPPGTYEPAYLGGRDPRVKGGPSLQQVMRDQLKPFTEPRGKPPRPSVLEAAKQTI
INVLEQTLDPSQKWTYAQACASLDKTTSSGHPHHVRKNECWNGETFTGKLADQASKAN
LMFEEGKHMTPVYTAALKDELVKTDKVYGKIKKRLLWGSDLSTMIRCARSFGGLMDEM
KAHCISLPVRVGMNMNEDGPIIFEKHSRYKYHYDADYSRWDSTQQRAVLAAALEIMVR
FSAEPQLAQIVAEDLLAPSVVDVGDFKISINEGLPSGVPCTSQWNSIAHWLLTLCALS
EVTKLSPDIIQANSMFSFYGDDEIVSTDIKLDPEKLTAKLKEYGLKPTRPDKTEGPLI
ISEDLNGLTFLRRTVTRDPAGWFGKLDQSSILRQMYWTRGPNHEDPNETMIPHSQRPI
QLMALLGEASLHGPSFYSKISKLVITELKEGGMDFYVPRQEPMFRWMRFSDLSTWEGD
RNLAPNFVNEDGVE"
mat_peptide <1..945
/gene="ORF1"
/product="p48"
mat_peptide 946..2043
/gene="ORF1"
/product="NTPase"
mat_peptide 2044..2574
/gene="ORF1"
/product="p22"
mat_peptide 2575..2973
/gene="ORF1"
/product="VPg"
mat_peptide 2974..3516
/gene="ORF1"
/product="Pro"
mat_peptide 3517..5046
/gene="ORF1"
/product="RdRp"
gene 5030..6676
/gene="ORF2"
CDS 5030..6676
/gene="ORF2"
/note="major capsid protein"
/codon_start=1
/product="VP1"
/protein_id="QBX92740.1"
/translation="MKMASNDAAPSNDGAAGLVPEINNEAMALDPVAGAAIAAPLTGQ
QNIIDPWIMNNFVQAPGGEFTVSPRNSPGEVLLNLELGPEINPYLAHLARMYNGYAGG
FEVQVVLAGNAFTAGKVIFAAIPPNFPTDNLSAAQITMCPHVIVDVRQLEPINLPMPD
VRNNFFHYNQGSDSRLRLIAMLYTPLRANNSGDDVFTVSCRVLTRPSPDFSFNFLVPP
TVESKTKPFSLPILTISEMSNSRFPVPIDSLHTSPTDNIVVQCQNGRVTLDGELMGTT
QLLPSQICAFRGVLTRSTSRASDQADTATPRLFNYYWHIQLDNLNGTPYDPAEDIPAP
LGTPDFRGKVFGVASQRNPDSTTRAHEAKVDTTSGRFTPKLGSLEISTESDDFAQNQP
TRFTPVGIGVDNEADFQQWTLPDYSGQFTHNMNLAPAVAPNFPGEQLLFFRSQLPSSG
GRSNGILDCLVPQEWVQHFYQESAPAQTQVALVRYVNPDTGRVLFEAKLHKLGYMTIA
KSGDSPITVPPNGYFRFESWVNPFYTLAPMGTGNGRRRIQ"
gene 6676..7440
/gene="ORF3"
CDS 6676..7440
/gene="ORF3"
/note="minor structural protein; small basic protein"
/codon_start=1
/product="VP2"
/protein_id="QBX92741.1"
/translation="MAGAFIAGLAGDMLTNTVGSLVNAGAGAINQKVDFENNKYLQNA
SFNHDKEMLNAQIEATKRLQADMIAIKQGVLTAGGFSPTDAARGAINAPITKVLDWSG
TRYWAPNATSTTSMSGGFTGQAVHRVTPNFTTNQAPKPTPSSGSSVRSNSTQLTNLSS
HSSGSSRSSGSTMVSSLPSSSRTRDWVNQQNFNLEPHMPGSLRTAFVTPPSSTASSLD
TVSTVPKSVLDSWTSAFNTRRQPLFAHLRRRGESNV"
ORIGIN
1 aacaacgaca aggaaaagtc ttcaggtgaa ggcttattca caaatatgtc ttccacctta
61 aagaaagccc tcggggctcg gcctaaacag cccgccccga gggacaaccc acaaaagcct
121 ccaagatcac caactcccga gttggtcaag gggatacccc ctcccccacc taatggtgaa
181 gaagaagaac cagtcattag gtatgaggtt aagagtggga tctctggcct gcccgagctc
241 acaacagtcc cccaaccgga tgtggccaac acggcattca gtgtcccacc gctgagcttg
301 agagaaaaca gggaggccaa ggaaccgctg acaggggcaa tattagagat gtgggatgga
361 gaaatatacc actatggctt gtacgtggaa aaaggcttag tgctgggtgt gcacaaacca
421 cctgcagcta taagcatggc aaaagtggag ctgacgccgt tgtcattgta ctggcgtgtg
481 gtttacaccc cccaatacct catctcccct gaaactctca ggaggctcaa cggagaggca
541 ttcccttaca ccgcctttga caacaactgc tatgcctttt gctgctgggt attagacctc
601 aatgactcat ggcttaacag gaggatggtg caaaggacaa caggcttctt tagaccttac
661 caagagtgga atagaaaacc cctgcctact atggatgact ccaaaatcaa gaaggtggca
721 aatatatttc tgtgttcatt gtccacgctg ttcaccagac ctataaaaga tctcatagga
781 aaaattaaac cattaaatat cttgaacatc ctggcaacgt gtgactggac gttcgccgga
841 atagtggagt ctttgatatt actcgctgaa ctctttggag ttttctggac acccccagat
901 gtgtctgcta tgatcgctcc cttacttgga gactacgagt tgcaagggcc agaagacctc
961 gccgttgagc tcgtacctgt ggtaatggga ggggttggtt tggtgctggg attcaccaaa
1021 gagaaaattg gcaaaatgtt gtcctcagca gcatcaacgc tcagggcttg taaagatctt
1081 ggtgcctatg gcttagagat actcaaattg gtcatgaagt ggttcttccc gaagaaagaa
1141 gaggccaatg agctagccat ggtgagagct atagaggatg ctgtactgga tcttgaggcg
1201 atagaaaata atcacatgac aactctgttg aaagacaaag acagcctagc aacctacatg
1261 aaaacactgg acatggagga ggaaaaagcc agaagattgt ccacgaaatc tgcatcccct
1321 gacatagttg ggacgatcaa cgccctgctg gctcgaatag cagcggctag gtcactagtc
1381 cacagggcca aggaggagtt atctagcagg atgagaccag tggttgttat gatatctggc
1441 aagccaggga taggcaagac tcatttggcc agggaggtgg caagaaaggt ggcatccact
1501 ctcacagggg atcaaagagt cgggctcata ccgagaaacg gtgtggacca ttgggatgca
1561 tacaaaggtg agagagtcgt gctgtgggac gactatggca tgagcaaccc cattcaagat
1621 gctctgcgca tacaagaatt ggctgatacg tgtcccctta ccttaaattg tgacagaatt
1681 gaaaataagg gaaaagtttt tgacagtgaa gtcataataa ttacaacaaa ccttgccaat
1741 ccagctccac ttgattatgt caactttgag gcctgttcca ggagaattga cttcctggtg
1801 tacgccgagg caccagaagt agaaaaggca aagcgagact ttcctggtca accagatatg
1861 tggaaggacg ccttcaagtc ggacttttca catatcaggt tgcaacttgc acctcagggc
1921 ggctttgaca agaatggtaa caccccacat gggaaaggag tgatgaagac cctcaccacc
1981 ggttccctta ttgcccgtgc atcaggctta ctgcatgaga ggatggatga atttgaactc
2041 caaggcccca caatcaccac tttcaatttc gaccggaaca gaatcaccgc attcagacaa
2101 ttggctgcag aaaataagta tgggttagtg gacaccatga gagttggcaa tcaattaaaa
2161 ggggtgaaaa ccatggaaga actcaaacaa gcaatcaaaa atgtgatcat caagaggtgc
2221 cgaatcatct acggtggctc aacgtatgac cttgaatctg atggcaaggg caaagttttg
2281 gtggaaaagg taaagaatac ctctgtacag accaacaacg agttggccgg agccctgcac
2341 cacctcaaac atgcccgaat caggtactat gtcagatgtg tgcaagaagc agtctactct
2401 atcatacaaa ttgctggcgc tgcgtttgtc accacacgca ttgcacgccg catgaacata
2461 caagaacttt ggtcgaagcc accattagac caaaatgagt tagaggctaa ggaagaggcc
2521 cccaagtcag aagatggcga gttcatcata tcttctaagg acatcaagga ggaaggaaag
2581 aagggcaaaa acaaaactgg ccgtggcaag aaacacacag cattctctag caagggtttg
2641 agcgatgagg agtatgacga gtacaagagg ataagagaag agagaaatgg gaagtactcc
2701 atagaggagt accttcaaga cagagacagg tactatgagg aactcgccat cgccaaggcc
2761 acggaagaag atttctgtga ggaggaggag atcaagatcc gtcagaggat cttccgtccc
2821 accaggaaac aaaggaagga agagagggcc acactagggc tagtaactgg ttcagaaatc
2881 agaaaaagaa accctgatga cttcaaacct aaagggaaac tgtgggccga tgataacaga
2941 agtgttgact acaatgagaa attggacttt gaggcccccc caagcatatg gtctaggatt
3001 gtgagctttg gttctggctg gggcttttgg gtatcaccaa gcctgttcat aacatcaact
3061 catgtaatcc ctgcaggcat aacagaggca tttggagtcc ccatcaagca aatccaggtc
3121 cacaaatcag gtgaattttg ccggttcaga ttcccaaaac caattagacc agatgtgaca
3181 ggaatgatct tggaagaagg tgcacctgag ggcactgtgg caaccgtgct catcaagcgc
3241 cctaccggag aactcatgcc ccttgcagcc agaatgggga cacacgcaac catgaaaatt
3301 caaggccgca tggttggcgg acagatgggt atgttgctca ctggttcaaa tgctaaaggg
3361 atggatttgg gaacaactcc tggtgattgt ggctgtccct acatctacaa gaggggcaat
3421 gactatatag tcattggggt gcatacagca gcagcccgtg gtggaaacac cgtcatctgt
3481 gccacacagg gaagtgaggg tgaggcaact cttgaaggtg gagatgacaa aggaacatat
3541 tgtggggcac ccattctagg ccctggaggg gcaccaaaat tgagcaccaa aaccaaattt
3601 tggaggtcat cgaacacgcc tcttccacca gggacatatg agcctgccta cctcggtggc
3661 cgtgacccgc gtgtcaaggg tgggccctcc ctgcagcagg taatgagaga ccagttgaag
3721 ccattcactg agcccagggg taaacctcca agaccaagtg tgttggaggc agccaaacaa
3781 accatcatca atgtcctcga acaaaccctg gacccctcac aaaaatggac ttacgcacag
3841 gcgtgtgctt cacttgacaa aaccacctcc agcgggcatc cccatcacgt ccggaagaat
3901 gaatgctgga acggtgagac cttcactggt aaattggcag accaagcatc aaaagcaaat
3961 ctaatgtttg aggaagggaa acacatgaca ccagtttaca cggcagccct caaggacgag
4021 ttggtcaaga ctgacaaagt ctatggaaag atcaaaaaga gactgctctg gggctctgac
4081 ttatccacca tgatccggtg tgccaggtcc tttggtgggc tcatggatga gatgaaggca
4141 cactgcatat cactcccagt ccgagtaggt atgaacatga atgaagatgg tccaataata
4201 tttgagaagc actccagata caagtaccat tatgatgcag attactcccg ctgggattca
4261 acacaacaga gggcggtatt agcagcagcc ttggaaatca tggtcaggtt ctctgcagag
4321 ccacaattgg cacagatagt cgctgaggat ctgttggccc ccagtgtggt agatgtagga
4381 gactttaaaa tttcaataaa tgaagggctc ccttctggtg taccatgcac ttctcaatgg
4441 aactccatcg cacactggct gctaactctc tgtgccttgt ctgaagtcac caaactgtcc
4501 cctgatatta tacaggcaaa ttccatgttc tcattctacg gtgatgacga gattgtcagc
4561 accgatataa aattggaccc tgaaaagtta accgccaaat tgaaagagta cggcctgaaa
4621 ccaactcgcc cagacaaaac cgagggaccc ctgatcatca gtgaggattt gaacggactc
4681 actttccttc gaaggacggt gactcgtgac ccagctggct ggtttggaaa attggaccaa
4741 agttcaatat tgaggcagat gtactggact agaggaccaa accatgaaga tcccaatgag
4801 acaatgatac cccactctca aagacccata cagctcatgg cattgcttgg tgaggcctcc
4861 cttcacggac cctctttcta cagcaagatt agtaaattgg tcataactga actcaaagaa
4921 ggtgggatgg acttttacgt gccaaggcag gaacccatgt tcaggtggat gaggttttct
4981 gatttgagca cgtgggaggg cgatcgcaat ctggctccca attttgtgaa tgaagatggc
5041 gtcgaatgac gctgctccat ctaatgatgg tgccgccggc ctcgtaccag agatcaataa
5101 tgaggcaatg gcgctagatc cagtggcggg tgcagcgata gcagcacccc ttactggcca
5161 gcaaaacata atagatccct ggattatgaa taattttgtg caagcacctg gtggtgagtt
5221 tacagtgtca cctaggaact cccctggtga agtacttcta aatttagaat taggcccaga
5281 aataaatccc tatctggcgc atcttgctag gatgtacaat ggttatgcag gtgggtttga
5341 ggtgcaggtg gtcctggctg gaaacgcgtt tacagcaggg aaagtgatct ttgcagctat
5401 accccccaat tttccaactg acaatttgag tgcagcgcag atcacaatgt gtcctcatgt
5461 aattgtggac gtcagacagt tggaaccaat caacctcccg atgcctgatg tccgcaacaa
5521 cttctttcat tacaatcaag gttctgattc gaggttacgc ttaattgcaa tgttgtatac
5581 accccttagg gcaaataatt ctggagatga tgttttcact gtgtcatgta gggtattgac
5641 taggcccagt cctgatttct cattcaattt cctcgtcccg cccactgtgg aatcaaagac
5701 aaaacctttt tccctcccta ttttgactat ctctgagatg tctaactcta ggtttccagt
5761 gccaattgat tctttgcaca ccagtccaac tgataacatt gttgttcagt gccaaaatgg
5821 gcgcgtcacc cttgacggtg agctaatggg caccactcaa ctcttgccga gtcagatatg
5881 tgcttttagg ggtgtgctca ccagatcaac aagcagggcc agtgaccaag ctgacacggc
5941 aacccccaga ctcttcaact actactggca catacaacta gacaacctaa atgggacccc
6001 gtatgatcct gcagaggaca taccagctcc tctggggacg ccagactttc ggggcaaagt
6061 ctttggcgta gccagccaga gaaaccctga cagcacaacg agggcacatg aggcaaaagt
6121 ggacacaaca tctggccgct tcaccccaaa attgggctcc ctagaaatat ccactgaatc
6181 tgatgacttt gcccaaaatc aaccaacaag attcacccca gttggcattg gagttgacaa
6241 tgaggcagac tttcaacaat ggaccttacc tgactattct ggtcagttca cccacaacat
6301 gaatctggcc ccagctgtcg ctcccaattt tcccggtgaa cagcttcttt tcttccgctc
6361 acagttgcca tcctctggcg gacggtccaa tggcattcta gactgcttgg tcccccagga
6421 atgggtccaa catttctacc aggagtccgc ccctgcccaa acgcaggtgg ctctggtcag
6481 gtatgtcaac cctgatactg gtagggtgtt atttgaggct aagctgcata agctaggcta
6541 catgaccata gctaagagtg gtgattctcc aataactgta cccccaaatg gatactttag
6601 gtttgaatct tgggtgaacc ccttttacac attagccccc atgggaactg ggaatgggcg
6661 cagaaggatc caataatggc tggagccttt atagcaggat tggctggtga catgctcaca
6721 aatactgtag ggtctttagt taatgcaggg gctggtgcta ttaatcaaaa ggttgatttt
6781 gaaaataaca aatatttaca aaatgcatct ttcaatcatg ataaggagat gttaaatgca
6841 caaattgagg caacaaagag gttgcaggct gacatgattg ctatcaaaca aggggttttg
6901 accgctggcg gtttttcccc cactgatgca gcccgtgggg ctattaatgc ccccataaca
6961 aaagttctgg actggagtgg aaccaggtac tgggcaccaa atgccacctc cacaacttca
7021 atgtcaggtg gcttcacagg tcaagctgtg cacagagtta caccaaattt tacaaccaat
7081 caagccccaa aacccacacc cagcagtggg tcttcagtga ggtcaaactc aacccaactc
7141 accaatttga gctcacactc atctgggtct tctcgatcca gcggatccac gatggtcagc
7201 tcgttaccat cttccagtag aactagagac tgggttaacc aacagaattt taatttggaa
7261 ccacacatgc ctggatctct caggacagct tttgtcactc caccatctag tacagcctct
7321 agcttagaca cggtctcaac cgtgcccaag agtgttttgg actcctggac atctgcgttt
7381 aacacgcgca gacagccgct tttcgcacac cttcgtagaa ggggggagtc aaatgtttag
7441 tgaaaagatt atttttaaat ttggtttgta atcggatt
//