Typing tool
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Typing tool
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Complete norovirus genomes
| MK764017 | GII.2 | |
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| GII.P16 |
ORF1: 4..5103
ORF2: 5084..6712
ORF3: 6712..7482
LOCUS MK764017 7482 bp RNA linear VRL 13-APR-2019
DEFINITION Norovirus GII isolate Hu/US/2017/GII.P16-GII.2/Osceola0226
nonstructural polyprotein (ORF1) and VP1 (ORF2) genes, complete
cds; and VP2 (ORF3) gene, partial cds.
ACCESSION MK764017
VERSION MK764017.1
KEYWORDS .
SOURCE Norovirus GII
ORGANISM Norovirus GII
Viruses; Riboviria; Orthornavirae; Pisuviricota; Pisoniviricetes;
Picornavirales; Caliciviridae; Norovirus; Norwalk virus.
REFERENCE 1 (bases 1 to 7482)
AUTHORS Barclay,L., Cannon,J.L., Wikswo,M.E., Phillips,A., Browne,H.,
Montmayeur,A.M., Tatusov,R.L., Burke,R.M., Hall,A.J. and Vinje,J.
TITLE Emergence and characterization of multiple viruses associated with
a novel GII.P16 polymerase in the United States, 2015-2018
JOURNAL Unpublished
REFERENCE 2 (bases 1 to 7482)
AUTHORS Barclay,L., Cannon,J.L., Mosher,L., Montmayeur,A.M., Tatusov,R.L.,
Chhabra,P. and Vinje,J.
TITLE Direct Submission
JOURNAL Submitted (05-APR-2019) Division of Viral Diseases, Centers for
Disease Control and Prevention, 1600 Clifton Road NE, Atlanta, GA
30329, USA
COMMENT ##Assembly-Data-START##
Assembly Method :: Geneious v. R10; SPAdes v. 3.6
Sequencing Technology :: Illumina
##Assembly-Data-END##
FEATURES Location/Qualifiers
source 1..7482
/organism="Norovirus GII"
/mol_type="genomic RNA"
/strain="Osceola0226"
/isolate="Hu/US/2017/GII.P16-GII.2/Osceola0226"
/isolation_source="stool"
/host="Homo sapiens"
/db_xref="taxon:122929"
/country="USA"
/collection_date="10-Feb-2017"
/note="genotype: GII.P16-GII.2"
gene 4..5103
/gene="ORF1"
CDS 4..5103
/gene="ORF1"
/codon_start=1
/product="nonstructural polyprotein"
/protein_id="QBX92730.1"
/translation="MQMASNDATVAVACNNNNDKEKSSGEGLFTNVSSTLKKALGARP
KQPAPRDKPQKPPRPPTPELVKRIPPPPPNGEEEEEPVIRYEVKSGISGLPELTTVPQ
PDVANTAFSVPPLSLRENKEAKEPLTGAILEMWDGEIYHYGLYVEKGLVLGVHKPPAA
ISMARVELTPLSLYWRVVYTPQYLISPETLRRLNGEAFPYTAFDNNCYAFCCWVLDLN
DSWLSRRMVQRTTGFFRPYQDWNRKPLPTMDDSKIKKVANIFLCSLSTLFTRPIKDLI
GKIKPLNILNILATCDWTFAGIVESLILLAELFGVFWTPPDVSAMIAPLLGDYELQGP
EDLAVELVPVVMGGIGLVLGFTKEKIGKMLSSAASTLRACKDLGAYGLEILKLVMKWF
FPKKEEANELAMVRAIEDAVLDLEAIENNHMTTLLKDKDSLATYMKTLDMEEEKARRL
STKSASPDIVGTINALLARIAAARSLVHRAKEELSSRMRPVVVMISGKPGIGKTHLAR
EVARKVASTLTGDQRVGLIPRNGVDHWDAYKGERVVLWDDYGMSNPIHDALRIQELAD
TCPLTLNCDRIENKGKVFDSEVIIITTNLANPAPLDYVNFEACSRRIDFLVYAEAPEV
EKAKRDFPGQPDMWKDAFKPDFSHIKLQLAPQGGFDKNGNTPHGKGVMKTLTTGSLIA
RASGLLHERMDEFELQGPTITTFNFDRNRITAFRQLAAENKYGLVDTMKVGNQLKGVK
TMEELKQAIRNVTIKRCQIIYGGSTYDLESDGKGKVLVEKVKNTFVQTNNELAGALHH
LKHARIRYYVKCVQEAVYSIMQIAGAAFVTTRIARRMNIQELWSKPQLDQNESETKEE
APKSEDDEFIISSKDIKEEGKKGKNKTGRGKKHTAFSSKGLSDEEYDEYKRIREERNG
KYSIEEYLQDRDRYYEELAIAKATEEDFCEEEEIKIRQRIFRPTRKQRKEERATLGLV
TGSEIRKRNPDDFKPKGKLWADDNRSVDYNEKLDFEAPPSIWSRIVSFGSGWGFWVSP
SLFITSTHVVPAGITEAFGVPIKQIQIHKSGEFCRFRFPKPIRPDVTGMILEEGAPEG
TVATVLIKRPTGELMPLAARMGTHATMKIQGRMVGGQMGMLLTGSNAKGMDLGTTPGD
CGCPYIYKRGNDYIVIGVHTAAARGGNTVICATQGSEGEATLEGGDDKGTYCGAPILG
PGGAPKLSTKTKFWRSSNTPLPPGTYEPAYLGGRDPRVKGGPSLQQVMRDQLKPFTEP
RGKPPRPSVLEAAKQTIINVLEQTLDPPQKWTYAQACASLDKTTSSGHPHHVRKNEFW
NGETFTGKLADQASKANLMFEEGKHMTPVYTAALKDELVKTEKIYGKIKKRLLWGSDL
STMIRCARSFGGLMDEMKAHCISLPVRVGMNMNEDSPIIFEKHSRYKYHYDADYSRWD
STQQRAVLAAALEIMVRFSAEPQLAQIVAEDLLAPSVVDVGDFKITINEGLPSGVPCT
SQWNSIAHWLLTLCALSEVTKLSPDIIQANSMFSFYGDDEIVSTDIKLDPEQLTAKLK
EYGLKPTRPDKTEGPLIISEDLNGLTFLRRTVTRDPAGWFGKLDQSSILRQMYWTRGP
NHEDPNETMIPHSQRPIQLMALLGEASLHGPSFYSKISKLVITELKEGGMDFYVPRQE
PMFRWMRFSDLSTWEGDRNLAPNFVNEDGVE"
mat_peptide 4..999
/gene="ORF1"
/product="p48"
mat_peptide 1000..2097
/gene="ORF1"
/product="NTPase"
mat_peptide 2098..2628
/gene="ORF1"
/product="p22"
mat_peptide 2629..3027
/gene="ORF1"
/product="VPg"
mat_peptide 3028..3570
/gene="ORF1"
/product="Pro"
mat_peptide 3571..5100
/gene="ORF1"
/product="RdRp"
gene 5084..6712
/gene="ORF2"
CDS 5084..6712
/gene="ORF2"
/note="major capsid protein"
/codon_start=1
/product="VP1"
/protein_id="QBX92731.1"
/translation="MKMASNDAAPSTDGAAGLVPESNNEVMALEPVAGAALAAPVTGQ
TNIIDPWIRANFVQAPNGEFTVSPRNAPGEVLLNLELGPELNPYLAHLARMYNGYAGG
MEVQVMLAGNAFTAGKLVFAAVPPHFPVENLSPQQITMFPHVIIDVRTLEPVLLPLPD
VRNNFFHYNQKDDPKMRIVAMLYTPLRSNGSGDDVFTVSCRVLTRPSPDFDFTYLVPP
TVESKTKPFTLPILTLGELSNSRFPVSIDQMYTSPNEVISVQCQNGRCTLDGELQGTT
QLQVSGICAFKGEVTAHLHDNDHLYNVTITNLNGSPFDPSEDIPAPLGVPDFQGRVFG
VISQRDKHNSPGHNEPANRGHDAVVPTYTAQYTPKLGQIQIGTWQTDDLTVNQPVKFT
PVGLNDTEHFNQWVVPRYAGALNLNTNLAPSVAPVFPGERLLFFRSYIPLKGGYGNPA
IDCLLPQEWVQHFYQEAAPSMSEVALVRYINPDTGRALFEAKLHRAGFMTVSSNTSAP
VVVPANGYFRFDSWVNQFYSLAPMGTGNGRRRVQ"
gene 6712..>7482
/gene="ORF3"
CDS 6712..>7482
/gene="ORF3"
/note="minor structural protein; small basic protein"
/codon_start=1
/product="VP2"
/protein_id="QBX92732.1"
/translation="MAGAFVAGLAGDVLSNGLSSLINAGANAINQRAEFDFNQKLQQN
SFNHDKEMLQAQIQATKQLQADMMAIKQGVLTAGGFSPADAARGAVNAPMTQALDWNG
TRYWAPNSMRTTSYSGKFTSTAPVRQADFQHTQSRPSSGSSVSSFATQSSRPTLTTTT
GSSHGTASSNSTRSTSLSQSTVSRATSRTGEWVRDQNRNLEPYMHGALQTAFVTPPSS
RASDGTVSTVPKGVLDSWTPAFNTRRQPLFAHLRKRGES"
ORIGIN
1 tgaatgcaga tggcgtctaa cgacgctacc gttgccgttg cttgcaacaa caacaacgac
61 aaagaaaaat cttcaggtga aggcttattc acaaatgtgt cttccacctt aaagaaagcc
121 ctcggggcta ggcccaaaca gcctgccccg agagacaaac cacaaaagcc cccaagacca
181 ccaactcccg agttggtcaa gaggataccc cctcctccac ctaatggcga agaagaagaa
241 gaaccagtca ttaggtatga ggttaagagt gggatctctg gcctgcccga gctcacaaca
301 gtcccccaac cggacgtggc caacacagca ttcagcgttc caccactgag cttgagagaa
361 aacaaggagg ccaaggaacc gctaacaggg gcaatattag agatgtggga tggagagata
421 taccactatg gcctgtacgt ggagaaaggc ttagtgttgg gtgtgcacaa accacctgca
481 gccataagca tggcaagagt ggagctgacg ccgttgtcat tgtactggcg tgtggtgtac
541 actccccaat acctcatctc ccctgaaact ctcaggaggc tcaacggaga ggcattccct
601 tacaccgcct ttgacaataa ctgctatgcc ttttgctgct gggtgttaga cctcaatgac
661 tcatggctta gcaggaggat ggtacaaaga acaacgggct tcttcagacc ttaccaagat
721 tggaacagaa aacccctgcc taccatggat gactccaaaa ttaagaaggt agcaaatata
781 ttcctatgtt cattgtccac attattcacc agacccataa aagacctcat aggaaaaata
841 aaaccattaa acatattgaa tatcctggca acgtgtgact ggacttttgc cggaatagtg
901 gagtctctga tattacttgc tgaactcttc ggagttttct ggacaccccc agatgtgtct
961 gctatgatcg ctcccttact cggggactac gagttgcaag ggccagaaga cctcgccgtt
1021 gaactcgtac ctgtggtaat gggggggatt ggtttggtgt tgggattcac caaagagaaa
1081 attggcaaaa tgttgtcctc agcagcatca acactcaggg cttgcaaaga tcttggtgcc
1141 tatggcttag agatactcaa attggtcatg aagtggttct tcccaaagaa agaggaggcc
1201 aatgagctag ccatggtgag ggccatagag gatgctgtac tagaccttga ggcaatagaa
1261 aataaccaca tgacaaccct gttgaaagac aaagacagct tagcaacgta catgaaaaca
1321 ctggacatgg aggaggagaa agccaggagg ttgtccacaa aatctgcatc ccctgacata
1381 gttgggacaa tcaacgccct gctggctcga atagcagcag ccaggtcatt agtccacaga
1441 gccaaggaag agctatctag caggatgagg ccagtagttg ttatgatatc tggcaaacca
1501 ggaataggta aaactcatct ggccagggag gtggcaagaa aggtggcatc cactctcaca
1561 ggggatcaaa gagtcggact cataccacga aacggtgtgg accattggga tgcatacaaa
1621 ggtgagagag tcgtgctgtg ggacgactat ggcatgagta accctattca tgatgctctt
1681 cgcatacaag aattggctga tacgtgtccc cttaccttaa attgtgacag aattgaaaat
1741 aagggaaaag tttttgacag tgaagtcata ataattacaa caaacctcgc caatccagcc
1801 ccacttgatt atgtcaactt tgaggcctgt tccaggagaa ttgatttcct ggtgtacgct
1861 gaggcaccag aagtagaaaa ggcaaaacgg gactttcctg gtcagccaga tatgtggaag
1921 gacgccttca agccagactt ttcacacatc aagctacagc ttgcacccca gggcggcttt
1981 gacaagaatg gcaacacccc acatgggaaa ggagtgatga agaccctcac taccggttct
2041 ctgattgccc gtgcatcagg cctactgcat gagaggatgg atgaatttga actccaaggt
2101 cccacaatca ccaccttcaa ttttgaccgg aacagaatca cggcattcag acaattggct
2161 gcagaaaaca agtatggatt ggtggatacc atgaaagttg gcaatcaatt aaaaggagtg
2221 aaaaccatgg aagaactcaa acaagcaatc aggaatgtga ccatcaagag gtgccagatc
2281 atctacggtg gttccacgta tgaccttgaa tctgatggta agggcaaagt tttggtggaa
2341 aaggtcaaga acacctttgt acagaccaac aacgagttgg ctggggccct gcaccatctc
2401 aaacatgccc gaatcaggta ctatgtcaaa tgtgtgcaag aagcagtcta ttccatcatg
2461 caaattgccg gcgctgcgtt tgtcaccaca cgcattgcac gccgcatgaa catacaagaa
2521 ctctggtcga agccacaact agatcaaaat gaatcagaga ctaaggaaga ggcccccaag
2581 tcagaagatg acgagttcat catatcttct aaggacatca aggaggaagg aaagaagggc
2641 aaaaacaaaa ctggccgtgg caagaaacac actgcattct ccagcaaggg cttgagcgat
2701 gaggagtatg acgagtacaa gaggataaga gaagagagaa atgggaagta ctctatagag
2761 gagtatcttc aagacagaga caggtactat gaggagctcg ccattgccaa ggccacggaa
2821 gaagacttct gtgaagagga ggagatcaaa atccgtcaga gaattttccg tcccaccagg
2881 aaacaaagaa aggaagagag ggccacatta gggctagtaa caggttcaga aatccgaaaa
2941 agaaaccctg atgacttcaa acccaaaggg aagctgtggg ccgatgacaa taggagtgtt
3001 gactacaatg agaaactgga ctttgaggcc cccccaagca tatggtctag gattgtgagc
3061 tttggttctg gctggggctt ctgggtgtca ccaagccttt tcataacatc aactcatgta
3121 gtccctgcag gcataacaga agcatttgga gtccccatca aacaaattca gatccacaaa
3181 tcaggcgaat tttgccgatt cagatttcca aaaccaatta gaccagatgt gacaggaatg
3241 atcctggaag aaggtgcgcc tgagggcacc gtggcaactg tgctcatcaa acgccccacc
3301 ggagagctca tgcctcttgc agccagaatg ggaacacacg caaccatgaa aattcaaggc
3361 cgcatggttg gcggacagat gggtatgttg ctcactggat caaatgctaa aggaatggac
3421 ttgggaacaa ctcctggtga ctgtggctgt ccttatatct ataaaagggg caatgactat
3481 atagtcattg gggtgcacac tgcagcagcc cgtggtggaa acaccgtcat ctgtgccaca
3541 cagggaagtg agggtgaggc aactcttgag ggtggagatg acaaaggaac atactgtggg
3601 gcacccattc taggccctgg gggtgcacca aaattgagca ccaaaaccaa attttggagg
3661 tcatcgaaca cgccccttcc accagggaca tatgagcctg cctacctcgg tggccgtgat
3721 ccgcgtgtta agggtgggcc ttccctgcag caggtaatga gagaccagtt gaagccattc
3781 actgaaccca ggggcaaacc tccaagacca agtgtattgg aagcagccaa acaaaccatc
3841 atcaatgtcc tcgaacaaac cctggaccct ccacaaaaat ggacatacgc acaggcgtgt
3901 gcctcacttg acaaaaccac ctccagcggg cacccccatc acgtccgaaa gaatgagttc
3961 tggaatggtg agaccttcac tggtaaactg gcagaccaag catcaaaggc aaacctaatg
4021 tttgaggaag ggaaacacat gacaccagtg tacacagcag cactcaagga cgagctagtc
4081 aagactgaga aaatctatgg aaagatcaag aagagactgc tctggggctc tgacttgtcc
4141 accatgatcc ggtgcgctag gtcatttggt gggctcatgg acgagatgaa ggcacactgc
4201 atatcactcc cagtccgagt tggcatgaat atgaatgaag atagcccaat aatatttgag
4261 aaacattcca gatacaaata tcactatgat gcagactact ctcgttggga ttcaacacaa
4321 cagagggcag tactagcagc agccttggaa atcatggtca gattctctgc agaaccacaa
4381 ttggcacaaa tagtcgctga ggatctgctg gctcctagtg tagtagatgt aggagacttt
4441 aaaattacaa taaatgaagg gctcccttct ggtgtgccat gcacttctca gtggaactcc
4501 atcgcacact ggctgctaac tctctgtgcc ttgtctgaag tcaccaaact gtcccctgac
4561 attatacagg caaattccat gttctcattt tacggtgatg acgagattgt cagcaccgat
4621 ataaaattgg accctgaaca gttaaccgcc aaattgaagg agtacggcct gaaaccaacc
4681 cgcccagaca aaaccgaggg acccctgatt atcagtgaag atttgaacgg tctcactttc
4741 ctccgaagga cggtgactcg tgacccagct ggctggtttg gaaaactgga ccaaagctca
4801 attctgaggc agatgtactg gactagagga ccaaatcatg aagaccccaa tgagacaatg
4861 ataccccatt ctcaaagacc catacagctc atggcactgc ttggtgaagc ctctcttcac
4921 ggaccctctt tctacagcaa aatcagtaaa ttggtcataa ctgaactcaa agaaggtggg
4981 atggactttt acgtgccaag gcaggaaccc atgttcaggt ggatgaggtt ttctgacttg
5041 agcacgtggg agggcgatcg caatctggct cccaattttg tgaatgaaga tggcgtcgaa
5101 tgacgccgct ccatctactg atggtgcagc cggcctcgtg ccagaaagta acaatgaggt
5161 catggctctt gaacccgtgg ctggtgccgc cttggcagcc ccggtcaccg gtcaaacaaa
5221 tattatagac ccttggatta gagcaaattt tgtccaggcc cctaatggtg aatttacagt
5281 ctctccccga aatgcccctg gtgaagtgct attgaatcta gagttgggtc cagaattaaa
5341 tccttatctg gcacatttag caagaatgta caatgggtat gccggtggga tggaggtgca
5401 ggtcatgttg gctgggaacg cgttcacagc cggcaagttg gtcttcgccg ccgtgccacc
5461 ccacttcccg gttgaaaacc ttagcccaca gcaaatcacc atgttccctc atgtgatcat
5521 agatgtgaga accttggaac ctgttctatt accactccct gatgttagga ataacttctt
5581 ccattataat cagaaagatg atcccaagat gagaattgtg gctatgcttt atacccccct
5641 caggtctaat ggttcaggtg atgatgtgtt tacagtctcc tgtagagtgt tgactagacc
5701 ttcccctgac tttgacttca catacctggt gccaccaaca gtggagtcta aaacaaagcc
5761 attcaccctc ccaatcctca cacttgggga actttccaat tctaggttcc cagtgtccat
5821 agaccagatg tacaccagcc ctaatgaagt tatatcagtg cagtgtcaaa atggtaggtg
5881 cacactggac ggggagctcc aagggacaac acaactccaa gtcagtggca tttgtgcttt
5941 caaaggtgaa gtgaccgccc acttgcatga caatgatcat ctatataatg ttaccatcac
6001 aaacttgaat gggtcccctt ttgatccctc cgaggatatc cctgcccctc tgggtgtgcc
6061 tgacttccag ggaagggttt ttggtgtcat ctcccaaaga gacaaacaca acagtcctgg
6121 gcataatgaa ccagcaaaca ggggacacga cgctgtggtc cctacttaca cagcacagta
6181 tactccaaaa ctgggacaaa ttcaaattgg cacgtggcaa actgacgacc tcacagtcaa
6241 ccaaccagtc aaattcaccc cagttggact caatgacact gaacatttca accaatgggt
6301 ggtccctagg tatgctggtg ccctaaacct caatacaaac cttgcccctt ctgttgctcc
6361 agtatttcca ggagagcgcc tgctcttctt cagatcatac attcccctca agggcggtta
6421 tggaaaccca gccattgatt gcctactacc acaagagtgg gtgcaacact tctatcagga
6481 agcagcccct tcaatgagtg aggtggccct cgtcaggtac atcaacccgg acactggtcg
6541 ggcactgttt gaggccaagc tccacagagc tggtttcatg acagtctcga gcaacaccag
6601 tgccccggtg gttgtgcctg ccaacggata cttcagattt gattcttggg tgaaccaatt
6661 ttattctctc gcccccatgg gaactgggaa tgggcgtaga agggttcaat aatggctgga
6721 gcttttgtag ctggtcttgc aggggacgtg ctcagcaatg ggcttagttc attaatcaat
6781 gcaggtgcta atgcaataaa tcagagggca gaatttgatt ttaatcagaa attgcagcaa
6841 aattctttta atcatgataa ggagatgttg caggctcaga ttcaggcaac taagcagctg
6901 caggcagaca tgatggctat aaaacaaggg gtcttgaccg ctggcggctt ttcccctgct
6961 gatgcagcca gaggtgctgt gaacgcgccc atgacacagg cgctggattg gaatggcaca
7021 aggtattggg caccaaactc catgaggacc acatcttatt ctggaaaatt cacatcaacc
7081 gccccagtga ggcaggctga cttccaacac acccaaagcc ggccttcgag tggctcctct
7141 gtgtcttcct ttgccactca gtcttcaagg ccaactctga ccacaaccac tggttcctca
7201 catggcacag cctcatcaaa ttcaactcgc agcacaagcc tctcccaatc aacggtctcc
7261 agagctacat ctaggactgg tgagtgggtt agagatcaaa atagaaattt ggaaccctac
7321 atgcatggtg ccttacagac agcctttgtc accccacctt ccagcagggc atctgatggg
7381 acagtctcaa ccgtcccgaa aggtgttttg gactcctgga cacctgcgtt taacacccgc
7441 aggcagccgc tttttgcaca cctccgtaag aggggggagt ca
//