Typing tool
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Typing tool
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Complete norovirus genomes
| MK762641 | GII.2 | |
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| GII.P16 |
ORF1: 1..4997
ORF2: 4978..6606
ORF3: 6606..7380
LOCUS MK762641 7380 bp RNA linear VRL 13-APR-2019
DEFINITION Norovirus GII isolate Hu/US/2016/GII.P16-GII.2/Davidson0488
nonstructural polyprotein (ORF1) gene, partial cds; VP1 (ORF2)
gene, complete cds; and VP2 (ORF3) gene, partial cds.
ACCESSION MK762641
VERSION MK762641.1
KEYWORDS .
SOURCE Norovirus GII
ORGANISM Norovirus GII
Viruses; Riboviria; Orthornavirae; Pisuviricota; Pisoniviricetes;
Picornavirales; Caliciviridae; Norovirus; Norwalk virus.
REFERENCE 1 (bases 1 to 7380)
AUTHORS Barclay,L., Cannon,J.L., Wikswo,M.E., Phillips,A., Browne,H.,
Montmayeur,A.M., Tatusov,R.L., Burke,R.M., Hall,A.J. and Vinje,J.
TITLE Emergence and characterization of multiple viruses associated with
a novel GII.P16 polymerase in the United States, 2015-2018
JOURNAL Unpublished
REFERENCE 2 (bases 1 to 7380)
AUTHORS Barclay,L., Cannon,J.L., Thomas,L.S., Montmayeur,A.M.,
Tatusov,R.L., Chhabra,P. and Vinje,J.
TITLE Direct Submission
JOURNAL Submitted (05-APR-2019) Division of Viral Diseases, Centers for
Disease Control and Prevention, 1600 Clifton Road NE, Atlanta, GA
30329, USA
COMMENT ##Assembly-Data-START##
Assembly Method :: Geneious v. R10; SPAdes v. 3.6
Sequencing Technology :: Illumina
##Assembly-Data-END##
FEATURES Location/Qualifiers
source 1..7380
/organism="Norovirus GII"
/mol_type="genomic RNA"
/strain="Davidson0488"
/isolate="Hu/US/2016/GII.P16-GII.2/Davidson0488"
/isolation_source="stool"
/host="Homo sapiens"
/db_xref="taxon:122929"
/country="USA"
/collection_date="27-Dec-2016"
/note="genotype: GII.P16-GII.2"
gene <1..4997
/gene="ORF1"
CDS <1..4997
/gene="ORF1"
/codon_start=3
/product="nonstructural polyprotein"
/protein_id="QBX91150.1"
/translation="LKKALGARPKQPAPRDKPQKPPRPPTPELVKRIPPPPPNGEEEE
EPVIRYEVKSGISGLPELTTVPQPDVANTAFSVPPLSLRENREAKEPLTGAILEMWDG
EIYHYGLYVEKGLVLGVHKPPAAISMARVELTPLSLYWRVVYTPQYLISPETLRRLNG
EAFPYTAFDNNCYVFCCWVLDLNDSWLSRRMVQRTTGFFRPYQEWNRKPLPTMDDSKI
KKVANIFLCSLSTLFTRPIKDLIGKIKPLNILNILATCDWTFAGIVESLILLAELFGV
FWTPPDVSAMIAPLLGDYELQGPEDLAVELVPVVMGGIGLVLGFTKEKIGKMLSSAAS
TLRACKDLGAYGLEILKLVMKWFFPKKEEANELAMVRAIEDAVLDLEAIENNHMTTLL
KDKDSLATYMKTLDMEEEKARRLSTKSASPDIVGTINALLARIAAARSLVHRAKEELS
SRIRPVVVMISGKPGIGKTHLAREVARKVASTLTGDQRVGLIPRNGVDHWDAYKGERV
VLWDDYGMSNPIHDALRIQELADTCPLTLNCDRIENKGKVFDSEVIIITTNLANPAPL
DYVNFEACSRRIDFLVYAEAPEVEKAKRDFPGQPDMWKDAFKPDFSHIKLQLAPQGGF
DKNGNTPHGKGVMKTLTTGSLIARASGLLHERMDEFELQGPTTTTFNFDRNRITAFRQ
LAAENKYGLVDTMKVGNQLKGVKTMEELKQAIRNVTIKRCRIIYGGSTYDLESDGKGK
VLVEKVKNTSVQTNNELAGALHHLKHARIRYYVKCVQEAVYSIIQIAGAAFVTTRIAR
RMNIQELWSKPQLDQNESETKEEAPKSEDDEFIISSKDIKEEGKKGKNKTGRGKKHTA
FSSKGLNDEEYDEYKRIREERNGKYSIEEYLQDRDRYYEELAIAKATEEDFCEEEEIK
IRQRIFRPTRKQRKEERATLGLVTGSEIRKRNPDDFKPKGKLWADDNRSVDYNEKLDF
EAPPSIWSRIVSFGSGWGFWVSPSLFITSTHVIPAGITEAFGVPIKQIQIHKSGEFCR
FRFPKPIRPDVTGMILEEGAPEGTVATVLIKRPTGELMPLAARMGTHATMKIQGRMVG
GQMGMLLTGSNAKGMDLGTTPGDCGCPYIYKRGNDYIVIGVHTAAARGGNTVICATQG
SEGEATLEGGDDKGTYCGAPILGPGGAPKLSTKTKFWRSSNTPLPPGTYEPAYLGGRD
PRVKGGPSLQQVMRDQLKPFTEPRGKPPRPSVLEAAKQTIINVLEQTLDPPQKWTYAQ
ACASLDKTTSSGYPHHVRKNEFWNGETFTGKLADQASKANLMFEEGKHMTPVYTASLK
DELVKTEKIYGKIKKRLLWGSDLSTMIRCARSFGGLMDEMKAHCISLPVRVGMNMNED
GPIIFEKHSRYRYHYDADYSRWDSTQQRAVLAAALEIMVRFSAEPQLAQIVAEDLLAP
SVVDVGDFKITINEGLPSGVPCTSQWNSIAHWLLTLCALSEVTKLSPDIIQTNSMFSF
YGDDEIVSTDIKLDPEQLTAKLKEYGLKPTRPDKTEGPLIISEDLNGLTFLRRTVTRD
PAGWFGKLDQSSILRQMYWTRGPNHEDPNETMIPHSQRPIQLMALLGEASLHGPSFYS
KISKLVITELKEGGMDFYVPRQEPMFRWMRFSDLSTWEGDRNLAPNFVNEDGVE"
mat_peptide <1..893
/gene="ORF1"
/product="p48"
mat_peptide 894..1991
/gene="ORF1"
/product="NTPase"
mat_peptide 1992..2522
/gene="ORF1"
/product="p22"
mat_peptide 2523..2921
/gene="ORF1"
/product="VPg"
mat_peptide 2922..3464
/gene="ORF1"
/product="Pro"
mat_peptide 3465..4994
/gene="ORF1"
/product="RdRp"
gene 4978..6606
/gene="ORF2"
CDS 4978..6606
/gene="ORF2"
/note="major capsid protein"
/codon_start=1
/product="VP1"
/protein_id="QBX91151.1"
/translation="MKMASNDAAPSTDGAAGLVPESNNEVMALEPVAGAALAAPVTGQ
TNIIDPWIRANFVQAPNGEFTVSPRNAPGEVLLNLELGPELNPYLAHLARMYNGYAGG
MEVQVMLAGNAFTAGKLVFAAVPPHFPVENLSPQQITMFPHVIIDVRTLEPVLLPLPD
VRNNFFHYNQKDDPKMRIVAMLYTPLRSNGSGDDVFTVSCRVLTRPSPDFDFTYLVPP
TVESKTKPFTLPILTLGELSNSRFPVSIDQMYTSPNEVISVQCQNGRCTLDGELQGTT
QLQVSGICAFKGEVTAHLHDNDHLYNVTITNLNGSPFDPSEDIPAPLGVPDFQGRVFG
IISQRDKHNSPGHNEPANRGHDAVVPTYTAQYTPKLGQIQIGTWQTDDLTVNQPVKFT
PVGLNDTEHFNQWVVPRYAGALNLNTNLAPSVAPVFPGERLLFFRSYIPLKGGYGNPA
IDCLLPQEWLQHFYQEAAPSMSEVALVRYINPDTGRALFEAKLHRAGFMTVSSNTSAP
VVVPANGYFRFDSWVNQFYSLAPMGTGNGRRRVQ"
gene 6606..>7380
/gene="ORF3"
CDS 6606..>7380
/gene="ORF3"
/note="minor structural protein; small basic protein"
/codon_start=1
/product="VP2"
/protein_id="QBX91152.1"
/translation="MAGAFVAGLAGDVLSNGLSSLINAGANAINQRAEFDFNQKLQQN
SFNHDKEMLQAQIQATKQLQADMMAIKQGVLTAGGFSPADAARGAVNAPMTQALDWNG
TRYWAPNSMRTTSYSGKFTSTAPVRQADFQHTQNRPSSGSSVSSFATQSSRPTLTTTT
GSSHGTASSNSTRSTSLSQSTVPRATSRTGEWVRDQNRNLEPYMHGALQTAFVTPPSS
RASDGTVSTVPKGVLDSWTPAFNTRRQPLFAHLRKRGESQ"
ORIGIN
1 ccttaaagaa agccctcggg gctaggccca aacagcctgc cccgagagac aaaccacaaa
61 agcccccaag accaccaact cccgagttgg tcaagaggat accccctcct ccacctaatg
121 gcgaagaaga agaagaacca gtcattaggt atgaggttaa gagtgggatc tctggcctgc
181 ccgagctcac aacagtcccc cagccggacg tggccaacac agcatttagt gttccaccac
241 tgagcttgag agaaaacagg gaggccaagg aaccgctaac aggggcaata ttagagatgt
301 gggatggaga gatataccac tatggcctgt acgtggagaa aggcttagtg ttgggtgtgc
361 acaaaccacc tgcagccata agcatggcaa gagtggagct gacgccgctg tcattgtact
421 ggcgtgtggt gtacactccc caatacctca tctcccctga aactctcagg aggctcaacg
481 gagaggcatt cccttacacc gcctttgaca acaactgcta tgtcttttgc tgctgggtgt
541 tagaccttaa tgattcatgg cttagcagga ggatggtaca aagaacaacg ggcttcttca
601 gaccttacca agagtggaac agaaaacccc tgcctaccat ggatgactcc aaaattaaga
661 aggtagcaaa tatattccta tgttcattgt ccacattatt caccagaccc ataaaagacc
721 tcataggaaa aattaaacca ttaaacatat tgaatatcct ggcaacgtgt gactggactt
781 ttgccggaat agtggagtct ctgatattac ttgctgaact cttcggagtt ttctggacac
841 ccccagatgt gtctgctatg atcgctccct tactcgggga ctacgagttg caaggaccag
901 aagacctcgc cgttgaactc gtacctgtgg tgatgggggg gattggcttg gtgttgggat
961 tcaccaaaga gaaaattggc aaaatgttgt cctcagcagc atcaacactc agggcttgca
1021 aagatcttgg tgcctatggc ttagagatac tcaaattggt catgaagtgg ttcttcccaa
1081 agaaagagga ggccaatgag ctagccatgg tgagggccat agaggatgct gtactagatc
1141 ttgaggcaat agaaaataac cacatgacaa ccctgttgaa agacaaagac agcttagcaa
1201 catacatgaa aacattggac atggaggagg agaaagccag gaggttgtcc acaaaatctg
1261 catcccctga catagttggg acaatcaacg ccctgctggc tcgaatagca gcggccaggt
1321 cgttagtcca cagggccaag gaagagctat ctagcaggat aagaccagta gttgttatga
1381 tatctggcaa accaggaata ggcaaaactc atctggccag ggaggtggca agaaaggtgg
1441 catccactct cacaggggat caaagagtcg gactcatacc acgaaacggt gtggaccatt
1501 gggatgcata caaaggtgag agagtcgtgc tgtgggacga ctatggcatg agtaacccca
1561 ttcatgatgc tcttcgcata caagaattgg ctgatacgtg tccccttacc ttaaattgtg
1621 acagaattga aaataaggga aaagtttttg acagtgaagt cataataatt acaacaaacc
1681 ttgccaaccc agccccactt gattatgtca actttgaggc ctgttccagg agaattgatt
1741 tcctggtgta cgctgaggca ccagaagtag aaaaggcaaa acgggacttt cctggtcagc
1801 cagatatgtg gaaggacgcc ttcaagccgg acttttcaca catcaagcta cagcttgcac
1861 cccagggcgg ctttgacaag aatggcaaca ccccacatgg gaaaggagtg atgaagaccc
1921 tcactaccgg ttctctgatt gcccgtgcat caggcctact gcatgagagg atggatgaat
1981 ttgagctcca aggtcccaca accaccacct tcaatttcga ccggaacaga atcacagcat
2041 tcagacaatt ggctgcagaa aacaagtatg gattggtgga taccatgaaa gttggcaatc
2101 aattaaaagg agtgaaaacc atggaagaac tcaaacaagc aatcaggaat gtgaccatca
2161 agaggtgccg gatcatctac ggtggttcca cgtatgacct tgaatctgat ggcaagggca
2221 aagttttggt ggaaaaggtc aagaacacct ctgtacagac caacaacgag ttggctgggg
2281 ccctgcacca tctcaaacat gcccgaatca ggtactatgt caaatgtgtg caagaagcag
2341 tctattctat catacaaatt gccggcgctg cgtttgtcac cacgcgcatt gcacgccgca
2401 tgaacataca agaactctgg tcgaagccac aattagatca aaatgaatca gagactaagg
2461 aagaggcccc caagtcagaa gatgacgagt tcatcatatc ttctaaggac atcaaggagg
2521 aaggaaagaa gggcaaaaac aaaactggcc gtggcaagaa acacactgca ttctccagca
2581 agggcttgaa cgatgaggag tatgacgagt acaagaggat aagagaagag agaaatggga
2641 agtactctat agaggagtat cttcaagaca gagacaggta ctatgaggag ctcgccattg
2701 ccaaggccac ggaagaagac ttctgtgaag aggaggagat caaaatccgt cagagaattt
2761 tccgtcccac caggaaacaa agaaaggaag agagggccac attaggacta gtaacaggtt
2821 cagaaatcag aaaaagaaac cctgatgact tcaaacccaa agggaagctg tgggccgatg
2881 acaacaggag tgttgactac aatgagaaac tggactttga ggccccccca agcatatggt
2941 ctaggattgt gagctttggt tctggctggg gcttctgggt gtcaccaagc cttttcataa
3001 catcaactca tgtaatcccc gcaggcataa cagaggcatt tggagtcccc atcaaacaaa
3061 ttcagatcca caaatcaggt gaattttgcc gattcagatt cccaaaacca attagaccag
3121 atgtgacagg aatgattttg gaagaaggtg cgcctgaggg caccgtggca actgtgctca
3181 tcaaacgccc caccggagag ctcatgcctc ttgcagccag aatgggaaca cacgcaacca
3241 tgaaaattca aggccgcatg gttggcggac agatgggtat gttgctcact ggatcaaatg
3301 ctaaaggaat ggatttggga acaactcctg gtgactgtgg ctgtccttac atctataaaa
3361 ggggcaatga ctatatagtc attggggtgc acactgcagc agcccgtggt ggaaacaccg
3421 tcatctgtgc cacacaggga agtgagggtg aggcaactct tgagggtgga gatgacaaag
3481 gaacgtactg tggggcaccc attctaggcc ctggaggtgc accaaaattg agcaccaaaa
3541 ccaagttttg gagatcatcg aacacgcccc ttccaccagg gacatatgag cctgcctacc
3601 tcggtggccg tgatccgcgt gttaagggtg ggccttccct gcagcaggta atgagagacc
3661 agttgaagcc attcactgaa cccaggggca aacctccaag accaagtgta ttggaagcag
3721 ccaaacaaac catcatcaat gttctcgaac aaaccctgga ccctccacaa aaatggacat
3781 acgcacaggc gtgtgcctca cttgacaaaa ccacctccag cgggtatccc catcacgtcc
3841 gaaagaatga attctggaat ggtgagacct tcactggtaa actggcagac caagcatcaa
3901 aagcaaacct aatgtttgag gaagggaaac acatgacacc agtgtacaca gcatcactca
3961 aggacgagct agtcaagact gagaaaatct atggaaagat caagaagaga ctgctctggg
4021 gctctgactt gtccaccatg atccggtgcg ctaggtcatt tggtgggctc atggacgaga
4081 tgaaggcaca ctgcatatca ctcccagtcc gagttggcat gaatatgaat gaagatggcc
4141 caataatatt tgagaaacat tccagataca gatatcacta tgatgcagac tactctcgtt
4201 gggattcaac acaacagagg gcagtactag cagcagcctt ggaaatcatg gtcagattct
4261 ctgcagaacc acaattggca caaatagtcg ctgaggatct gttggcccct agtgtagtag
4321 atgtaggaga ctttaaaatt acaataaatg aagggctccc ttctggtgtg ccatgcactt
4381 ctcaatggaa ctccatcgca cactggctgc taactctctg tgccttgtct gaagtcacca
4441 aactgtcccc tgacattata cagacaaatt ccatgttctc attttacggt gatgacgaga
4501 ttgtcagcac cgacataaaa ttggaccctg aacaattaac cgccaaattg aaggagtacg
4561 gcctgaaacc aacccgccca gacaaaaccg agggacccct gattatcagt gaagatttga
4621 acggtctcac tttcctccga aggacggtga ctcgtgaccc agctggctgg tttggaaaac
4681 tggaccaaag ctcgattttg aggcagatgt actggactag aggaccaaat catgaagacc
4741 ccaatgagac aatgataccc cattctcaaa gacccataca gctcatggca ctgcttggtg
4801 aagcctctct tcacggaccc tctttctaca gtaaaatcag taaattggtc ataactgaac
4861 tcaaagaagg tgggatggac ttttacgtgc caaggcagga acccatgttc aggtggatga
4921 ggttttctga cttgagcacg tgggagggcg atcgcaatct ggctcccaat tttgtgaatg
4981 aagatggcgt cgaatgacgc cgctccatct actgatggtg cagccggcct cgtgccagaa
5041 agtaacaatg aggtcatggc tcttgaaccc gtggctggtg ccgccttggc agccccggtc
5101 accggtcaaa caaatattat agacccttgg attagagcaa attttgtcca ggcccccaat
5161 ggtgaattta cagtctctcc ccgaaatgcc cctggtgaag tgctattgaa tctagagttg
5221 ggtccagaat taaatcctta tctggcacat ttagcaagaa tgtataatgg gtatgccggt
5281 gggatggagg tgcaggtcat gttggctggg aacgcgttca cagccggcaa gttggtcttc
5341 gccgccgtgc ctcctcactt cccggttgaa aaccttagcc cacagcaaat caccatgttc
5401 cctcatgtga tcatagatgt gagaaccttg gaacctgttt tattaccact ccctgatgtt
5461 aggaataatt tcttccatta taatcagaaa gatgatccca agatgaggat tgtggctatg
5521 ctttataccc ccctcaggtc taatggttca ggtgatgatg tgttcacagt ctcctgtaga
5581 gtgttgacta gaccttcccc tgactttgac ttcacatacc tggtgccacc aacagtggag
5641 tctaaaacaa agccattcac cctcccaatc ctcacacttg gggaactatc caattctagg
5701 ttcccagtgt ccatagacca gatgtacacc agccctaatg aagttatatc agtgcagtgt
5761 caaaatggta ggtgcacact ggacggggag ctccaaggaa caacacaact ccaagtcagt
5821 ggcatttgtg ctttcaaagg tgaagtgacc gcccacttgc atgacaatga tcacctatat
5881 aatgttacca tcacaaactt gaatgggtcc ccttttgatc cctccgagga catccctgcc
5941 cctctgggtg tgcctgactt ccagggaagg gtttttggta tcatctctca aagagacaaa
6001 cacaatagtc ctgggcataa tgaaccagca aacaggggac acgacgctgt ggtccctact
6061 tacacagcac agtacactcc aaaactggga caaattcaaa ttggcacatg gcagactgac
6121 gatcttacag tcaaccaacc agtcaaattc accccagttg gactcaatga cactgaacat
6181 tttaatcaat gggtggtccc taggtatgct ggtgccctaa acctcaatac aaaccttgcc
6241 ccttctgttg ctccagtatt tccaggagag cgtctgctct tcttcagatc atacattccc
6301 ctcaagggcg gttatggaaa cccagccatt gattgcctac taccacaaga gtggctgcaa
6361 cacttctatc aggaagcagc cccttcaatg agtgaggtgg ccctcgtcag atacatcaac
6421 ccggacactg gtcgggcact gtttgaggcc aagctccaca gagctggttt catgacagtc
6481 tcgagcaaca ccagtgcccc ggtggttgtg cctgccaacg gatacttcag atttgattct
6541 tgggtgaacc aattctattc tctcgccccc atgggaactg ggaatgggcg cagaagggtt
6601 caataatggc tggagctttt gtagctggtc ttgcagggga cgtgctcagc aatgggctta
6661 gttcattaat caatgcgggt gctaatgcaa taaatcagag ggcagaattt gattttaatc
6721 agaaattgca gcaaaattct tttaatcatg ataaggagat gttgcaggct cagattcagg
6781 caactaagca gctgcaggca gacatgatgg ctataaaaca aggggtcttg accgctggcg
6841 gcttttcccc tgctgatgca gccagaggtg ctgtgaacgc gcccatgaca caggcgctgg
6901 attggaatgg cacaaggtat tgggcaccaa actccatgag gaccacatct tattctggaa
6961 aattcacatc aaccgcccca gtgaggcagg ctgacttcca gcacacccaa aaccggcctt
7021 cgagtggctc ctctgtgtct tccttcgcca ctcagtcttc aaggccaact ttgaccacaa
7081 ccactggttc ctcacatggc acagcctcat caaattcaac tcgcagcaca agcctctccc
7141 aatcaacggt ccccagagct acatctagga ctggtgagtg ggttagagat caaaatagaa
7201 atttggaacc ctacatgcat ggtgccttac agacagcctt tgtcacccca ccttccagca
7261 gggcatctga cgggacagtc tcaaccgtcc cgaaaggtgt tttggactcc tggacacctg
7321 cgtttaacac ccgcaggcag ccgctttttg cacacctccg taagaggggg gagtcacaag
//