Typing tool
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Typing tool
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Complete norovirus genomes
| MK762634 | GII.2 | |
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| GII.P16 |
ORF1: 1..5058
ORF2: 5039..6667
ORF3: 6667..7419
LOCUS MK762634 7419 bp RNA linear VRL 13-APR-2019
DEFINITION Norovirus GII isolate Hu/US/2017/GII.P16-GII.2/Chittenden0425
nonstructural polyprotein (ORF1) gene, partial cds; VP1 (ORF2)
gene, complete cds; and VP2 (ORF3) gene, partial cds.
ACCESSION MK762634
VERSION MK762634.1
KEYWORDS .
SOURCE Norovirus GII
ORGANISM Norovirus GII
Viruses; Riboviria; Orthornavirae; Pisuviricota; Pisoniviricetes;
Picornavirales; Caliciviridae; Norovirus; Norwalk virus.
REFERENCE 1 (bases 1 to 7419)
AUTHORS Barclay,L., Cannon,J.L., Wikswo,M.E., Phillips,A., Browne,H.,
Montmayeur,A.M., Tatusov,R.L., Burke,R.M., Hall,A.J. and Vinje,J.
TITLE Emergence and characterization of multiple viruses associated with
a novel GII.P16 polymerase in the United States, 2015-2018
JOURNAL Unpublished
REFERENCE 2 (bases 1 to 7419)
AUTHORS Barclay,L., Cannon,J.L., Devlin,V., Montmayeur,A.M., Tatusov,R.L.,
Chhabra,P. and Vinje,J.
TITLE Direct Submission
JOURNAL Submitted (05-APR-2019) Division of Viral Diseases, Centers for
Disease Control and Prevention, 1600 Clifton Road NE, Atlanta, GA
30329, USA
COMMENT ##Assembly-Data-START##
Assembly Method :: Geneious v. R10; SPAdes v. 3.6
Sequencing Technology :: Illumina
##Assembly-Data-END##
FEATURES Location/Qualifiers
source 1..7419
/organism="Norovirus GII"
/mol_type="genomic RNA"
/strain="Chittenden0425"
/isolate="Hu/US/2017/GII.P16-GII.2/Chittenden0425"
/isolation_source="stool"
/host="Homo sapiens"
/db_xref="taxon:122929"
/country="USA"
/collection_date="30-Nov-2017"
/note="genotype: GII.P16-GII.2"
gene <1..5058
/gene="ORF1"
CDS <1..5058
/gene="ORF1"
/codon_start=1
/product="nonstructural polyprotein"
/protein_id="QBX91129.1"
/translation="NNNNDKEKSSGEGLFTNMSSTLKKALGARPKQPAPRDKPQKPPR
PPTPELVKRIPPPPPNGEEEEEPVIRYEVKSGISGLPELTTVPQPDVANTAFSVPPLS
LRENREAKEPLTGAILEMWDGEIYHYGLYVEKGLVLGVHKPPAAVSMARVELTPLSLY
WRVVYTPQYLISPETLRRLNGEAFPYTAFDNNCYAFCCWVLDLNDSWLSRRMVQRTTG
FFRPYQEWNRKPLPTMDDSKIKKVANIFLCSLSTLFTRPIKDLIGKIKPLNILNILAT
CDWTFAGIVESLILLAELFGVFWTPPDVSAMIAPLLGDYELQGPEDLAVELVPVVMGG
IGLVLGFTKEKIGKMLSSAASTLRACKDLGAYGLEILKLVMKWFFPKKEEANELAMVR
AIEDAVLDLEAIENNHMTTLLKDKDSLATYMKTLDMEEEKARRLSTKSASPDIVGTIN
ALLARIAAARSLVHRAKEELSSRIRPVVVMISGKPGIGKTHLAREVARKVASTLTGDQ
RVGLIPRNGVDHWDAYKGERVVLWDDYGMSNPIHDALRIQELADTCPLTLNCDRIENK
GKVFDSEVIIITTNLANPAPLDYVNFEACSRRIDFLVYADAPEVEKAKRDFPGQPDMW
KDAFKPDFSHIKLQLAPQGGFDKNGNTPHGKGVMKTLTTGSLIARASGLLHERMDEFE
LQGPTITTFNFDRNRITAFRQLAAENKYGLVDTMRVGNQLKGVKTMEELKQAIRNVTI
KRCRIIYGGSTYDLESDGKGKVLVEKVKNTSVQTNNELAGALHHLKHARIRYYVKCVQ
EAVYSIIQIAGAAFVTTRIARRMNIQELWSKPQLDQNESETKEEAPKSGDDEFIISSK
DIKEEGKKGKNKTGRGKKHTAFSSKGLSDEEYDEYKRIREERNGKYSIEEYLQDRDRY
YEELAIAKATEEDFCEEEEIKIRQRIFRPTRKQRKEERATLGLVTGSEIRKRNPDDFK
PKGKLWADDNRSVDYNEKLDFEAPPSIWSRIVSFGSGWGFWVSPSLFITSTHVIPAGI
TEAFGVPIKQIQIHKSGEFCRFRFPKPIRPDVTGMILEEGAPEGTVATVLIKRPTGEL
MPLAARMGTHATMKIQGRMVGGQMGMLLTGSNAKGMDLGTTPGDCGCPYIYKRGNDYI
VIGVHTAAARGGNTVICATQGSEGEATLEGGDDKGTYCGAPILGPGGAPKLSTKTKFW
RSSNTPLPPGTYEPAYLGGRDPRVKGGPSLQQVMRDQLKPFTEPRGKPPRPSVLEAAK
QTIINVLEQTLDPPQKWTYAQACASLDKTTSSGHPYHVRKNEFWNGETFTGKLADQAS
KANLMFEEGKHMTPVYTAALKDELVKTEKIYGKIKKRLLWGSDLSTMIRCARSFGGLM
DEMKAHCISLPVRVGMNMNEDGPIIFEKHSRYKYHYDADYSRWDSTQQRAVLAAALEI
MVRFSAEPQLAQIVAEDLLAPSVVDVGDFKITINEGLPSGVPCTSQWNSIAHWLLTLC
ALSEVTKLSPDIIQANSMFSFYGDDEIVSTDIKLDPEQLTARLKEYGLKPTRPDKTEG
PLIISEDLNGLTFLRRTVTRDPAGWFGKLDQSSILRQMYWTRGPNHEDPNETMIPHSQ
RPVQLMALLGEASLHGPSFYSKISKLVITELKEGGMDFYVPRQEPMFRWMRFSDLSTW
EGDRNLAPNFVNEDGVE"
mat_peptide <1..954
/gene="ORF1"
/product="p48"
mat_peptide 955..2052
/gene="ORF1"
/product="NTPase"
mat_peptide 2053..2583
/gene="ORF1"
/product="p22"
mat_peptide 2584..2982
/gene="ORF1"
/product="VPg"
mat_peptide 2983..3525
/gene="ORF1"
/product="Pro"
mat_peptide 3526..5055
/gene="ORF1"
/product="RdRp"
gene 5039..6667
/gene="ORF2"
CDS 5039..6667
/gene="ORF2"
/note="major capsid protein"
/codon_start=1
/product="VP1"
/protein_id="QBX91130.1"
/translation="MKMASNDAAPSTDGAAGLVPESNNEVMALEPVAGAALAAPVTGQ
TNIIDPWIRANFVQAPNGEFTVSPRNAPGEVLLNLELGPELNPYLAHLARMYNGYAGG
MEVQVMLAGNAFTAGKLVFAAVPPHFPVENLSPQQITMFPHVIIDVRTLEPVLLPLPD
VRNNFFHYNQKDDPKMRIVAMLYTPLRSNGSGDDVFTVSCRVLTRPSPDFDFTYLVPP
TVESKTKPFTLPILTLGELSNSRFPVSIDQMYTSPNEVISVQCQNGRCTLDGELQGTT
QLQASGICAFKGEVTAHLHDNDHLYNVTITNLNGSPFDPSEDIPAPLGVPDFQGRVFG
IISQRDKHNSPGHNEPANRGHDAVVPTYTAQYTPKLGQIQIGTWQTDDLTVNQPVKFT
PVGLNDTEHFNQWVVPRYAGALNLNTNLAPSVAPVFPGERLLFFRSYIPLKGGYGNPA
IDCLLPQEWVQHFYQEAAPSMSEVALVRYVNPDTGRALFEAKLHRAGFMTVSSNTSAP
VVVPANGYFRFDSWVNQFYSLAPMGTGNGRRRVQ"
gene 6667..>7419
/gene="ORF3"
CDS 6667..>7419
/gene="ORF3"
/note="minor structural protein; small basic protein"
/codon_start=1
/product="VP2"
/protein_id="QBX91131.1"
/translation="MAGAFVAGLAGDVLSNGLSSLINAGANAINQRAEFDFNQKLQQN
SFNHDKEMLQAQIQATKQLQADMMAIKQGVLTAGGFSPADAARGAVNAPMTQALDWNG
TRYWAPNSMRTTSYSGKFTSTAPVRQADFQYTQSRPSSGSSVSSFATQSSRPTLTTTT
GSSHGTVSSNSTRSTSLSQSTVSRATSRTGEWVRDQNRNLEPYMHGALQTAFVTPPSS
RASDGTVSTVPKGVLDSWTPAFNTRRQPLFAHL"
ORIGIN
1 aacaacaaca acgacaaaga aaaatcttca ggtgaaggct tattcacaaa tatgtcttcc
61 accttaaaga aagccctcgg ggctaggccc aaacagcctg ccccgagaga caaaccacaa
121 aagcccccaa gaccaccaac tcccgagttg gtcaagagga taccccctcc tccacctaat
181 ggcgaagaag aagaagaacc agtcattagg tatgaggtta agagtgggat ctctggcctg
241 cccgagctca caacagtccc ccaaccggac gtggccaaca cagcattcag tgttccacca
301 ctgagcttga gagaaaacag ggaggccaag gaaccgctaa caggggcaat attagagatg
361 tgggatggag agatatacca ctatggcctg tacgttgaga aaggcttagt gttgggtgtg
421 cacaaaccac ctgcagccgt aagcatggca agagtggagc tgacgccgct gtcattgtac
481 tggcgtgtgg tgtacactcc ccaatacctc atctcccctg aaactctcag gagactcaac
541 ggagaggcat tcccttacac cgcctttgac aataactgct atgccttttg ctgctgggtg
601 ttagacctca atgactcatg gcttagcagg aggatggtgc aaagaacaac gggcttcttc
661 agaccttatc aagagtggaa cagaaaaccc ctgcccacca tggatgactc caaaatcaag
721 aaggtagcaa atattttcct atgttcattg tccacattat tcaccagacc cataaaagac
781 ctcataggaa aaattaaacc attaaacata ttgaatatcc tggcaacgtg tgactggact
841 tttgccggaa tagtggagtc tctgatatta cttgctgaac tcttcggagt tttctggaca
901 cccccagatg tgtctgctat gatcgctccc ttactcgggg actacgagtt gcaggggcca
961 gaagacctcg ccgttgaact cgtacctgtg gtaatggggg ggattggttt ggtgttggga
1021 ttcaccaaag agaaaattgg caaaatgttg tcctcagcag catcaacact cagggcttgc
1081 aaagatcttg gtgcctatgg cttagagata ctcaaattgg tcatgaagtg gttcttccca
1141 aagaaagagg aggccaatga gttagccatg gtgagggcca tagaggatgc tgtactagat
1201 cttgaggcaa tagaaaataa ccacatgaca accctgttga aagacaaaga cagcttggca
1261 acatacatga aaacactgga catggaggag gagaaagcca ggaggttgtc cacaaaatct
1321 gcatcccctg acatagttgg gacaatcaac gccctgctgg ctcgaatagc agcggccagg
1381 tcattagtcc acagggccaa ggaagagcta tctagcagga taagaccagt agttgtcatg
1441 atatctggca aaccaggaat aggcaaaact catctggcca gggaggtggc aagaaaggtg
1501 gcgtccactc tcacagggga tcaaagagtc ggactcatac caagaaacgg tgtggaccat
1561 tgggatgcat acaaaggtga aagggtcgtg ctgtgggacg actatggcat gagtaacccc
1621 atacatgatg ctcttcgcat acaagaattg gctgatacgt gtccccttac cttaaattgt
1681 gacagaattg aaaacaaggg aaaagttttt gacagtgagg tcataataat tacaacaaac
1741 cttgccaatc cagccccact tgattatgtt aattttgagg cctgttccag gagaattgat
1801 ttcctggtgt acgctgatgc accagaagta gaaaaggcaa aacgggactt tcctggtcag
1861 ccagatatgt ggaaggacgc cttcaagccg gatttttcac acatcaagct acagcttgca
1921 ccccagggcg gctttgacaa gaatggcaac accccacatg ggaaaggagt gatgaagacc
1981 ctcactaccg gttctctgat tgcccgtgca tcaggcctac tgcatgagag gatggatgaa
2041 tttgaactcc aaggtcccac aatcaccacc ttcaatttcg accggaacag aatcacagca
2101 ttcagacaat tggctgcaga aaacaagtat ggattggtgg ataccatgag agttggcaat
2161 caactaaaag gagtgaaaac catggaggaa cttaaacagg caatcaggaa tgtgaccatc
2221 aagaggtgcc ggatcatcta cggtggctcc acgtatgacc ttgaatctga tggcaagggc
2281 aaagttttgg tggaaaaggt caagaacacc tctgtacaga ccaacaacga gttggctggg
2341 gccctgcacc atctcaaaca cgcccgaatc aggtactatg tcaagtgtgt gcaagaagca
2401 gtctattcca tcatacaaat tgccggcgct gcgtttgtca ccacgcgcat tgcacgccgc
2461 atgaacatac aagaactctg gtcgaagcca caattagatc aaaatgaatc agagactaag
2521 gaagaggccc ccaagtcagg agatgacgag ttcatcatat cttctaagga catcaaggag
2581 gaaggaaaga agggcaaaaa caaaactggc cgtggcaaga aacacactgc attctccagc
2641 aagggcttga gcgatgagga gtacgacgag tacaagagga taagagaaga gaggaatggg
2701 aagtactcca tagaggagta tcttcaagac agagacaggt actatgagga gctcgccatt
2761 gccaaggcca cggaagaaga cttctgtgaa gaggaggaga tcaaaatccg tcagagaatt
2821 ttccgtccca ccaggaaaca aagaaaggaa gagagggcca cattagggct agtaacaggt
2881 tcagaaatca gaaaaagaaa ccctgatgac ttcaaaccca aagggaagct gtgggccgat
2941 gacaacagga gtgttgacta caatgagaaa ctggactttg aggccccccc aagcatatgg
3001 tctaggattg tgagctttgg ttctggctgg ggcttctggg tgtcaccaag ccttttcata
3061 acgtcaactc atgtaatccc cgcaggcata acagaagcat ttggagtccc catcaaacaa
3121 attcagatcc acaaatcagg tgaattttgc cgattcagat tcccaaaacc aattagacca
3181 gatgtgacag ggatgatctt ggaagaaggt gcgcctgagg gcaccgtggc aactgtgctc
3241 atcaaacgtc ccaccggaga gctcatgcct cttgcagcca gaatgggaac acacgcaacc
3301 atgaaaattc aaggccgcat ggttggcgga cagatgggta tgttgctcac tggatcaaat
3361 gctaaaggaa tggatttggg aacaactcct ggtgactgtg gctgtcctta catctacaaa
3421 aggggcaatg actatatagt cattggggtg cacactgcag cagcccgtgg tggaaacacc
3481 gtcatctgtg ccacacaggg aagtgagggt gaggcaactc ttgagggtgg agatgacaaa
3541 ggaacatatt gtggggcacc cattctaggc cctgggggtg caccaaaatt gagcaccaaa
3601 accaaatttt ggaggtcatc gaacacgccc cttccaccag ggacatatga acctgcctac
3661 ctcggtggcc gtgatccgcg tgttaagggt gggccctccc tgcagcaggt aatgagagac
3721 cagttgaagc cattcactga acccaggggc aaacctccaa gaccaagtgt attggaagca
3781 gccaagcaaa ccatcatcaa tgtcctcgaa caaaccctgg accctccaca aaaatggaca
3841 tacgcacagg cgtgtgcctc acttgacaaa accacctcca gcgggcatcc ctatcacgtc
3901 cgaaagaatg aattctggaa tggtgagacc ttcactggta aattggcaga ccaagcatca
3961 aaagcaaacc taatgtttga ggaagggaaa cacatgacac cagtgtacac agcagcactc
4021 aaggacgagc tagtcaagac tgagaaaatc tatggaaaga tcaagaagag actgctctgg
4081 ggctctgact tgtccaccat gatccggtgc gctaggtcat ttggtgggct catggacgag
4141 atgaaggcac actgcatatc actcccagtc cgagttggca tgaatatgaa tgaagatggc
4201 ccaataatat ttgagaaaca ttccagatac aaatatcact atgatgcaga ctactctcgt
4261 tgggattcaa cacaacagag ggcagtacta gcagcagcct tggaaattat ggtcagattc
4321 tctgcagaac cacaattggc acaaatagtc gctgaggatc tgctggcccc tagtgtagta
4381 gatgtaggag actttaaaat tacaataaat gaagggctcc cctctggtgt gccatgcact
4441 tctcaatgga actccatcgc acactggctg ctaactctct gtgccttgtc tgaagtcacc
4501 aaactgtccc ctgacattat acaggcaaat tccatgttct cattttacgg tgatgacgag
4561 attgtcagca ccgacataaa attggaccct gaacagttaa ccgccagatt gaaggagtac
4621 ggcctgaaac caacccgccc agacaaaacc gagggacccc tgattatcag tgaagatttg
4681 aacggactca ctttcctccg aaggacagtg actcgtgacc cagctggctg gtttggaaaa
4741 ctggaccaaa gctcaatttt gaggcagatg tactggacta gaggaccaaa tcatgaagac
4801 cccaatgaga caatgatacc ccattctcaa agacccgtgc agctcatggc actgcttggt
4861 gaagcctctc ttcacggacc ctctttctac agtaaaatca gtaaattggt cataactgaa
4921 ctcaaagaag gtgggatgga cttttacgtg ccaaggcagg aacccatgtt caggtggatg
4981 aggttttctg acttgagcac gtgggagggc gatcgcaatc tggctcccaa ttttgtgaat
5041 gaagatggcg tcgaatgacg ccgctccatc tactgatggt gcagccggcc tcgtgccaga
5101 aagtaacaat gaggtcatgg ctcttgaacc cgtggctggt gccgccttgg cagccccggt
5161 cactggtcaa acaaatatta tagacccttg gattagagca aattttgtcc aggcccccaa
5221 tggtgaattt acagtctctc cccgtaatgc ccctggtgaa gtgctattga atctagagtt
5281 gggtccagaa ttaaatcctt atctggcaca tttagcaaga atgtacaatg ggtatgccgg
5341 tgggatggag gtgcaggtca tgttggctgg gaacgcgttc acagccggca agttggtctt
5401 cgccgccgtg ccacctcact tcccagttga aaaccttagc ccacagcaaa tcaccatgtt
5461 ccctcatgtg atcatagatg tgagaacctt ggaacctgtt ctgttaccac tccctgatgt
5521 taggaataat ttcttccatt ataatcagaa agatgatccc aagatgagaa ttgtggctat
5581 gctttatacc cccctcaggt ctaatggttc aggtgatgat gtgtttacag tctcctgcag
5641 agtgttgact agaccttccc ctgactttga cttcacatac ctggtgccac caacagtgga
5701 gtctaaaaca aaaccattca ccctcccaat cctcacactt ggggaacttt ccaattccag
5761 gttcccagtg tccatagacc agatgtacac cagccctaat gaagttatat cagtgcagtg
5821 tcaaaatggt aggtgcacac tggacgggga gctccaggga acaacacaac tccaagccag
5881 tggcatttgt gctttcaaag gtgaagtgac cgcccacttg catgacaatg atcacctata
5941 taatgtcacc atcacaaact tgaatgggtc tccttttgat ccctccgagg acatccctgc
6001 ccctctgggt gtgcctgact tccagggaag ggtttttggt atcatctccc aaagggacaa
6061 acacaatagt cctgggcata atgaaccagc aaacagggga cacgacgctg tggtccccac
6121 ttacacagca cagtacactc caaaactggg acaaattcaa attggcacat ggcagactga
6181 cgaccttaca gtcaaccaac cagtcaaatt caccccagtt ggactcaatg acactgaaca
6241 ttttaaccaa tgggtggtcc ccaggtatgc tggtgcccta aacctcaata caaaccttgc
6301 tccttctgtt gctccagtat ttccaggaga gcgcctgtta ttcttcagat catacattcc
6361 cctcaagggc ggttatggaa acccagccat tgattgccta ctaccacaag agtgggtgca
6421 acacttctat caggaagcag ccccttcaat gagtgaggtg gccctcgtca gatacgtcaa
6481 cccggacact ggtcgggcac tgtttgaggc caagctccac agagctggtt tcatgacagt
6541 ctcgagcaac accagtgccc cggtggttgt gcctgccaac ggatacttca gatttgattc
6601 ttgggtgaac caattctatt ctctcgcccc catgggaact gggaatgggc gcagaagggt
6661 tcaataatgg ctggagcttt tgtagctggt cttgcagggg acgtgctcag caatgggctt
6721 agttcattaa tcaatgcagg tgctaatgca ataaatcaga gggcagaatt tgattttaat
6781 cagaaattgc agcaaaattc ttttaatcat gataaggaga tgttgcaggc tcagattcag
6841 gcaactaagc agctgcaggc agacatgatg gctataaaac aaggggtctt gaccgctggc
6901 ggcttttccc ctgctgatgc agccagaggt gctgtgaacg cgcccatgac acaagcgctg
6961 gattggaatg gtacgaggta ttgggcacca aactccatga ggaccacatc ttattctgga
7021 aaattcacat caaccgcccc agtgaggcag gccgacttcc agtacaccca aagccggcct
7081 tcgagtggct cctctgtgtc ttcctttgcc actcagtctt caaggccaac cctgaccaca
7141 accactggtt cctcacatgg cacagtctca tcaaattcaa ctcgcagcac aagcctctcc
7201 caatcaacgg tctccagagc tacatctagg actggtgagt gggttagaga tcaaaataga
7261 aatttggaac cctacatgca tggtgcctta cagacagcct ttgtcacccc accttccagc
7321 agggcatctg acgggacagt ctcaaccgtc ccgaaaggtg ttttggactc ctggacacct
7381 gcgtttaaca cccgcaggca gccgcttttt gcacacctc
//