Typing tool
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Typing tool
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Complete norovirus genomes
| MK762631 | GII.2 | |
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| GII.P16 |
ORF1: 1..5091
ORF2: 5072..6700
ORF3: 6700..7479
LOCUS MK762631 7490 bp RNA linear VRL 13-APR-2019
DEFINITION Norovirus GII isolate Hu/US/2017/GII.P16-GII.2/Pinellas0160
nonstructural polyprotein (ORF1) gene, partial cds; and VP1 (ORF2)
and VP2 (ORF3) genes, complete cds.
ACCESSION MK762631
VERSION MK762631.1
KEYWORDS .
SOURCE Norovirus GII
ORGANISM Norovirus GII
Viruses; Riboviria; Orthornavirae; Pisuviricota; Pisoniviricetes;
Picornavirales; Caliciviridae; Norovirus; Norwalk virus.
REFERENCE 1 (bases 1 to 7490)
AUTHORS Barclay,L., Cannon,J.L., Wikswo,M.E., Phillips,A., Browne,H.,
Montmayeur,A.M., Tatusov,R.L., Burke,R.M., Hall,A.J. and Vinje,J.
TITLE Emergence and characterization of multiple viruses associated with
a novel GII.P16 polymerase in the United States, 2015-2018
JOURNAL Unpublished
REFERENCE 2 (bases 1 to 7490)
AUTHORS Barclay,L., Cannon,J.L., Heberlein-Larson,L.A., Montmayeur,A.M.,
Tatusov,R.L., Chhabra,P. and Vinje,J.
TITLE Direct Submission
JOURNAL Submitted (05-APR-2019) Division of Viral Diseases, Centers for
Disease Control and Prevention, 1600 Clifton Road NE, Atlanta, GA
30329, USA
COMMENT ##Assembly-Data-START##
Assembly Method :: Geneious v. R10; SPAdes v. 3.6
Sequencing Technology :: Illumina
##Assembly-Data-END##
FEATURES Location/Qualifiers
source 1..7490
/organism="Norovirus GII"
/mol_type="genomic RNA"
/strain="Pinellas0160"
/isolate="Hu/US/2017/GII.P16-GII.2/Pinellas0160"
/isolation_source="stool"
/host="Homo sapiens"
/db_xref="taxon:122929"
/country="USA"
/collection_date="21-Feb-2017"
/note="genotype: GII.P16-GII.2"
gene <1..5091
/gene="ORF1"
CDS <1..5091
/gene="ORF1"
/codon_start=1
/product="nonstructural polyprotein"
/protein_id="QBX91120.1"
/translation="ASNDATVAVACNNNNDKEKSSGEGLFTNVSSTLKKALGARPKQP
APRDKLQKPPRPPTPELVKRIPPPPPNGEEEEEPVIRYEVKSGIFGLPELTTVPQPDV
ANTAFSVPPLSLRENREAKEPLTGAILEMWDGEIYHYGLYVEKGLVLGVHKPPAAISM
ARVELTPLSLYWRVVYTPQYLISPETLRRLNGEAFPYTAFDNNCYAFCCWVLDLNDSW
LSRRMVQRTTGFFRPYQDWNRKPLPTMDDSKIKKVANIFLCSLSTLFTRPIKDLIGKI
KPLNILNILATCDWTFAGIVESLILLAELFGVFWTPPDVSAMIAPLLGDYELQGPEDL
AVELVPVVMGGIGLVLGFTKEKIGKMLSSAASTLRACKDLGAYGLEILKLVMKWFFPK
KEEANELAMVRAIEDAVLDLEAIENNHMTTLLKDKDSLATYMKTLDMEEEKARRLSTK
SASPDIVGTINALLARIAAARSLVHRAKEELSSRMRPVVVMISGKPGIGKTHLAREVA
RKVASTLTGDQRVGLIPRNGVDHWDAYKGERVVLWDDYGMSNPIHDALRIQELADTCP
LTLNCDRIENKGKVFDSEVIIITTNLANPAPLDYVNFEACSRRIDFLVYAEAPEVEKA
KRDFPGQPDMWKDAFKPDFSHIKLQLAPQGGFDKNGNTPHGKGVMKTLTTGSLIARAS
GLLHERMDEFELQGPTITTFNFDRNRITAFRQLAAENKYGLVDTMKVGNQLKGVKTME
ELKQAIRNVTIKRCQIIYGGSTYDLESDGKGKVLVEKVKNTSVQTNNELAGALHHLKH
ARIRYYVKCVQEAVYSIIQIAGAAFVTTRIARRMNIQELWSKPQLDQNESETKEEAPK
SEDDEFIISSKDIKEEGKKGKNKTGRGKKHTAFSSKGLSDEEYDEYKRIRDERNGKYS
IEEYLQDRDRYYEELAIAKATEEDFCEEEEIKIRQRIFRPTRRQRKEERATLGLVTGS
EIRKRNPDDFKPKGKLWADDNRSVDYNEKLDFEAPPSIWSRIVSFGSGWGFWVSPSLF
ITSTHVIPAGITEAFGVPIKQIQIHKSGEFCRFRFPKPIRPDVTGMILEEGAPEGTVA
TVLIKRPTGELMPLAARMGTHATMKIQGRMVGGQMGMLLTGSNAKGMDLGTTPGDCGC
PYIYKRGNDYIVIGVHTAAARGGNTVICATQGSEGEATLEGGDDKGTYCGAPILGPGG
APKLSTKTKFWRSSNTPLPPGTYEPAYLGGRDPRVKGGPSLQQVMRDQLKPFTEPRGK
PPRPSVLEAAKQTIINVLEQTLDPPQKWTYAQACASLDKTTSSGYPHHVRKNEFWNGE
TFSGKLADQASKANLMFEEGKHMTPVYTAALKDELVKTEKIYGKIKKRLLWGSDLSTM
IRCARSFGGLMDEMKAHCISLPVRVGMNINEDGPIIFEKHSRYKYHYDADYSRWDSTQ
QRAVLAAALEIMVRFSAEPQLAQIVAEDLLAPSVVDVGDFKITINEGLPSGVPCTSQW
NSIAHWLLTLCALSEVTKLSPDIIQASSMFSFYGDDEIVSTDIKLDPEQLTAKLKEYG
LKPTRPDKTEGPLIISEDLNGLTFLRRTVTRDPAGWFGKLDQSSILRQMYWTRGPNHE
DPNETMIPHSQRPIQLMALLGEASLHGPSFYSKISKLVITELKEGGMDFYVPRQEPMF
RWMRFSDLSTWEGDRNLAPNFVNEDGVE"
mat_peptide <1..987
/gene="ORF1"
/product="p48"
mat_peptide 988..2085
/gene="ORF1"
/product="NTPase"
mat_peptide 2086..2616
/gene="ORF1"
/product="p22"
mat_peptide 2617..3015
/gene="ORF1"
/product="VPg"
mat_peptide 3016..3558
/gene="ORF1"
/product="Pro"
mat_peptide 3559..5088
/gene="ORF1"
/product="RdRp"
gene 5072..6700
/gene="ORF2"
CDS 5072..6700
/gene="ORF2"
/note="major capsid protein"
/codon_start=1
/product="VP1"
/protein_id="QBX91121.1"
/translation="MKMASNDAAPSTDGAAGLVPESNNEVMALEPVAGAALAAPVTGQ
TNIIDPWIRANFVQAPNGEFTVSPRNAPGEVLLNLELGPELNPYLAHLARMYNGYAGG
MEVQVMLAGNAFTAGKLVFAAVPPHFPVENLSPQQITMFPHVIIDVRTLEPVLLPLPD
VRNNFFHYNQKDDPKMRIVAMLYTPLRSNGSGDDVFTVSCRVLTRPSPDFDFTYLVPP
TVESKTKPFTLPILTLGELSNSRFPLSIDQMYTSPNEVISVQCQNGRCTLDGELQGTT
QLQVSGICAFKGEVTAHLHDNDHLYNVTITNLNGSPFDPSEDIPAPLGVPDFQGRVFG
IISQRDKHNSPGHNEPANRGHDAVVPTYTAQYTPKLGQIQIGTWQTDDLTVNQPVKFT
PVGLNDTEHFNQWVVPRYAGALNLNTNLAPSVAPVFPGERLLFFRSYIPLKGGYGNPA
IDCLLPQEWVQHFYQEAAPSMSEVALVRYINPDTGRALFEAKLHRAGFMTVSSNTSAP
VVVPANGYFRFDSWVNQFYSLAPMGTGNGRRRVQ"
gene 6700..7479
/gene="ORF3"
CDS 6700..7479
/gene="ORF3"
/note="minor structural protein; small basic protein"
/codon_start=1
/product="VP2"
/protein_id="QBX91122.1"
/translation="MAGAFVAGLAGDVLSNGLSSLINAGANSINQRAEFDFNQKLQQN
SFNHDKEMLQAQIQATKQLQADMMAIKQGVLTAGGFSPADAARGAVNAPMTQALDWNG
TRYWAPNSMRTTSYSGKFTSTAPVRQADFQHTQSRPSSGSSVSSFATQSSRPTLTTTT
GSSHGTASSNSTRSTSLSQSTVSRATSRTGEWVRDQNRNLEPYMHGALQTAFVTPPSS
RASDGTVSTVPKGVLDSWTPAFNTRRQPLFAHLRKRGESQA"
ORIGIN
1 gcgtctaacg acgctaccgt tgccgttgct tgcaacaaca acaacgacaa agaaaaatct
61 tcaggtgaag gcttattcac aaatgtgtcc tccaccttaa agaaagccct cggggctagg
121 cccaaacagc ctgccccgag agacaaacta caaaagcccc caagaccacc aactcccgag
181 ttggtcaaga ggataccccc tcccccacct aatggcgaag aagaagaaga accagtcatt
241 aggtatgagg ttaagagtgg gatctttggc ctgcccgagc tcacaacagt cccccaaccg
301 gacgtggcca acacagcatt cagcgttcca ccactgagct tgagagaaaa cagggaggcc
361 aaggaaccgc taacaggggc aatattagag atgtgggatg gagagatata ccactatggc
421 ctgtacgtgg agaaaggctt agtgttgggt gtgcacaaac cacctgcagc cataagcatg
481 gcaagagtgg agctgacgcc gttgtcattg tactggcgtg tggtgtacac tccccaatac
541 ctcatctccc ctgaaactct caggaggctc aacggagagg cattccctta caccgccttt
601 gacaataact gctatgcctt ttgctgctgg gtgttagacc tcaatgactc atggcttagc
661 aggaggatgg tacagagaac aacgggcttc ttcagacctt accaagattg gaacagaaaa
721 cccctgccta ccatggatga ctccaaaatt aagaaggtag caaatatatt cctatgttca
781 ttgtccacat tattcaccag acccataaaa gacctcatag gaaaaataaa accattaaac
841 atattgaata tcctggcaac gtgtgactgg acttttgccg gaatagtgga gtctctgata
901 ttacttgctg aactcttcgg agttttctgg acacccccag atgtgtctgc tatgatcgct
961 cccttactcg gggactacga gttgcaaggg ccagaagacc tcgccgttga actcgtacct
1021 gtggtaatgg gggggattgg tctggtgttg ggattcacca aagagaaaat tggcaaaatg
1081 ttgtcctcag cagcatcaac actcagggct tgcaaagatc ttggcgccta tggcttagag
1141 atactcaaat tggtcatgaa gtggttcttc ccaaagaaag aggaggccaa tgagctagcc
1201 atggtgaggg ccatagagga tgctgtacta gaccttgagg caatagaaaa taaccacatg
1261 acaaccctgt tgaaagacaa agacagctta gcaacgtaca tgaaaacact ggacatggag
1321 gaggagaaag ccaggaggtt gtccacaaaa tctgcatccc ctgacatagt tgggacaatc
1381 aacgccctgc tggctcgaat agcagcagcc aggtcattag tccacagggc caaggaagag
1441 ctatctagca ggatgaggcc agtagttgtt atgatatctg gcaaaccagg aataggcaaa
1501 actcatctgg ccagggaggt ggcaagaaag gtggcatcca ctctcacagg ggaccaaaga
1561 gtcggactca taccacgaaa cggtgtggac cattgggatg catacaaagg tgagagagtc
1621 gtgctgtggg acgactatgg catgagtaac cccattcatg atgctcttcg catacaagaa
1681 ttggctgata cgtgtcccct caccttaaat tgtgacagaa ttgaaaataa gggaaaagtt
1741 tttgacagtg aagtcataat aattacaaca aacctcgcca atccagcccc acttgattat
1801 gtcaactttg aggcctgttc caggagaatt gatttcctgg tgtacgctga ggcaccagaa
1861 gtagaaaagg caaaacggga ctttcctggt cagccagata tgtggaagga cgccttcaag
1921 ccagactttt cacacatcaa gctacagctt gcaccccagg gcggctttga taagaatggc
1981 aacaccccac atgggaaagg agtgatgaag accctcacta ccggttctct gattgcccgt
2041 gcatcaggcc tactgcatga gaggatggat gaatttgaac tccaaggtcc cacaatcacc
2101 accttcaatt tcgaccggaa cagaatcacg gcattcagac aattggctgc agaaaacaag
2161 tatggattgg tggataccat gaaagttggc aatcaattaa aaggagtgaa aaccatggaa
2221 gaactcaaac aagcaatcag gaatgtgacc atcaagaggt gccagatcat ctacggtggt
2281 tccacgtatg accttgaatc tgatggcaag ggcaaagttt tggtggaaaa ggtcaagaac
2341 acctctgtac agaccaacaa cgagttggct ggggccctgc accatctcaa acatgcccga
2401 atcaggtact atgtcaaatg tgtgcaagaa gcagtctatt ccatcataca aattgccggc
2461 gctgcgtttg tcaccacacg cattgcacgc cgcatgaaca tacaagaact ctggtcgaag
2521 ccacaactag atcaaaatga atcagagact aaggaagagg cccccaagtc agaagatgat
2581 gagttcatca tatcttctaa ggacatcaag gaggaaggaa agaagggcaa aaacaaaact
2641 ggccgtggca agaaacacac tgcattctcc agcaagggct tgagcgatga ggagtatgac
2701 gagtacaaga ggataagaga cgagagaaat gggaagtact ctatagagga gtatcttcaa
2761 gacagagaca gatactatga ggagctcgcc attgccaagg ccacggaaga agacttctgt
2821 gaagaggagg agatcaaaat ccgtcagaga attttccgtc ccaccaggag acaaagaaag
2881 gaagagaggg ccacattggg gctagtaaca ggttcagaaa tccgaaaaag aaaccctgat
2941 gacttcaaac ccaaagggaa gctgtgggcc gatgacaaca ggagtgttga ctacaatgag
3001 aaactggact ttgaggcccc cccaagcata tggtctagga ttgtgagctt tggttctggc
3061 tggggcttct gggtgtcacc aagccttttc ataacatcaa ctcatgtaat ccccgcaggc
3121 ataacagaag catttggagt ccccatcaaa caaattcaga tccacaaatc aggcgaattt
3181 tgccgattca gattcccaaa accaattaga ccagatgtga caggaatgat cttggaagaa
3241 ggtgcgcctg agggcaccgt ggcaactgtg ctcatcaaac gccccaccgg agagctcatg
3301 cctcttgcag ccagaatggg aacacacgca accatgaaaa ttcaaggccg catggttggc
3361 ggacagatgg gtatgttgct cactggatca aatgctaaag gaatggactt gggaacaact
3421 cctggtgact gtggctgtcc ttatatctat aaaaggggca atgactatat agtcattggg
3481 gtgcacactg cagcagcccg tggtggaaac accgtcatct gtgccacaca gggaagtgag
3541 ggtgaggcaa ctcttgaggg tggagatgac aaaggaacat actgtggggc acccattcta
3601 ggccctgggg gtgcaccaaa attgagcacc aaaaccaaat tttggaggtc atcgaacacg
3661 ccccttccac cagggacata tgagcctgcc tacctcggtg gccgtgatcc gcgtgttaag
3721 ggtgggcctt ccctgcagca ggtaatgaga gaccagttga agccattcac tgaacccagg
3781 ggcaaacctc caagaccaag tgtattggaa gcagccaaac aaaccatcat caatgtcctc
3841 gaacaaaccc tggaccctcc acaaaaatgg acatacgcac aggcgtgtgc ctcacttgac
3901 aaaaccacct ccagcgggta cccccatcac gtccgaaaga atgaattctg gaatggtgag
3961 accttctctg gtaaactggc agaccaagca tcaaaagcaa acctaatgtt tgaggaaggg
4021 aaacacatga caccagtgta cacagcagca ctcaaggacg agctagtcaa gactgagaaa
4081 atctatggaa agatcaagaa gagactgctc tggggctctg acttgtccac catgatccgg
4141 tgcgctaggt catttggtgg gctcatggac gagatgaagg cacactgcat atcactccca
4201 gtccgagttg gcatgaatat aaatgaagat ggcccaataa tatttgagaa acattccaga
4261 tacaaatatc actatgatgc agactactct cgttgggatt caacacaaca gagggcagta
4321 ctagcagcag ccttggaaat catggtcaga ttctctgcag aaccacaatt ggcacaaata
4381 gtcgctgagg atctgctggc tcctagtgta gtagatgtag gagactttaa aattacaata
4441 aatgaagggc tcccttctgg tgtgccatgc acttctcagt ggaactccat cgcacactgg
4501 ctgctaactc tctgtgcctt gtctgaagtc accaaactgt cccctgacat tatacaggca
4561 agttccatgt tctcatttta cggtgatgac gagattgtca gcaccgatat aaaattggac
4621 cctgaacagt taaccgccaa attgaaggag tacggcctga aaccaacccg cccagacaaa
4681 accgagggac ccctgattat cagtgaagat ttgaacggtc tcactttcct ccgaaggacg
4741 gtgactcgtg acccagctgg ctggtttgga aaactggacc aaagctcaat tctgaggcag
4801 atgtactgga ctagaggacc aaatcatgaa gaccccaatg agacaatgat accccattct
4861 caaagaccca tacagctcat ggcactgctt ggtgaagcct ctcttcacgg accctctttc
4921 tatagtaaaa tcagtaaatt ggtcataact gaactcaaag aaggtgggat ggacttttac
4981 gtgccaaggc aggaacccat gttcaggtgg atgaggtttt ctgacttgag cacgtgggag
5041 ggcgatcgca atctggctcc caattttgtg aatgaagatg gcgtcgaatg acgccgctcc
5101 atctactgat ggtgcagccg gcctcgtgcc agaaagtaac aatgaggtca tggctcttga
5161 acccgtggct ggtgccgcct tggcagcccc ggtcaccggt caaacaaata ttatagaccc
5221 ttggattaga gcaaattttg tccaggcccc taatggtgaa ttcacagtct ctccccgaaa
5281 tgcccctggt gaagtgctac tgaatctaga gttgggtcca gaattaaatc cttatctggc
5341 acatttagca agaatgtaca atgggtatgc cggtgggatg gaggtgcagg tcatgttggc
5401 tgggaacgcg ttcacagccg gcaagttggt cttcgccgcc gtgccacccc acttcccggt
5461 tgaaaacctt agcccacagc aaatcaccat gttccctcat gtgatcatag atgtgagaac
5521 tttggaacct gttttattac cactccctga tgttaggaat aacttcttcc attataatca
5581 gaaagatgat cccaagatga gaattgtggc tatgctttac acccccctca ggtctaatgg
5641 ttcaggtgat gatgtgttta cagtctcctg tagagtgttg actagacctt cccctgactt
5701 tgacttcaca tacctggtgc caccaacagt ggagtccaaa acaaagccat tcaccctccc
5761 aatcctcaca cttggggaac tttccaattc taggttccca ttgtccatag accagatgta
5821 caccagccct aatgaagtta tatcagtgca gtgtcaaaat ggtaggtgca cactggacgg
5881 ggagctccaa gggacaacac aactccaagt cagtggtatt tgtgctttca aaggtgaagt
5941 gaccgcccac ttgcatgaca atgatcatct atataatgtt accatcacaa acttgaatgg
6001 gtcccctttt gatccctccg aggatatccc tgcccctctt ggtgtgcctg acttccaggg
6061 aagggttttt ggtatcatct cccaaagaga caaacacaac agtcctgggc ataatgaacc
6121 agcaaacagg ggacacgacg ctgtggtccc tacttacaca gcacagtata ctccaaaact
6181 gggacaaatt caaattggca cgtggcaaac tgacgacctt acagtcaacc aaccagtcaa
6241 attcacccca gttggactca atgacactga acactttaac caatgggtgg tccctaggta
6301 tgctggtgcc ctaaacctca atacaaacct tgccccttct gttgctccag tatttccagg
6361 agagcgcctg ctcttcttca gatcatacat tcccctcaag ggcggttatg gaaacccagc
6421 cattgattgc ctactaccac aagagtgggt gcaacacttc tatcaggaag cagccccttc
6481 aatgagtgag gtggccctcg tcaggtacat caacccggac actggtcggg cactgtttga
6541 ggccaagctc cacagagctg gtttcatgac agtctcgagc aacaccagtg ccccggtggt
6601 tgtgcctgcc aacggatact tcagatttga ttcttgggtg aaccaatttt attctctcgc
6661 ccccatggga actgggaatg ggcgtagaag ggttcaataa tggctggagc ttttgtagct
6721 ggtcttgcag gggacgtgct cagcaatggg cttagttcat taatcaatgc aggtgctaat
6781 tcaataaatc aaagggcaga atttgatttt aaccagaaat tgcagcaaaa ttcttttaat
6841 catgataagg agatgttgca ggctcagatt caggcaacta agcagctgca ggcagacatg
6901 atggctataa aacaaggggt cttgaccgct ggcggctttt cccctgctga tgcagccaga
6961 ggtgctgtga acgcgcccat gacacaggcg ctggattgga atggcacaag gtattgggca
7021 ccaaactcca tgaggaccac atcttattct ggaaaattca catcaaccgc cccagtgagg
7081 caggctgact tccaacacac ccaaagccgg ccttcgagtg gctcctctgt gtcttccttt
7141 gccactcagt cttcaaggcc aactctgacc acaaccactg gttcctcaca tggcacagcc
7201 tcatcaaatt caactcgcag cacaagcctc tcccaatcaa cggtctccag agctacatct
7261 aggactggtg agtgggttag agatcaaaat agaaatttgg aaccctacat gcatggtgcc
7321 ttacagacag cctttgtcac cccaccttcc agcagggcat ctgacgggac agtctcaacc
7381 gtcccgaaag gtgttttgga ctcctggaca cctgcgttta acacccgcag gcagccgctt
7441 tttgcacacc tccgtaagag gggggagtca caagcttagt gaaaaggtga
//