Typing tool
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Typing tool
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Complete norovirus genomes
| MK762630 | GII.4 Sydney | |
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| GII.P31 |
ORF1: 1..5052
ORF2: 5033..6655
ORF3: 6655..7461
LOCUS MK762630 7507 bp RNA linear VRL 13-APR-2019
DEFINITION Norovirus GII isolate Hu/US/2015/GII.Pe-GII.4 Sydney/Broward1056
nonstructural polyprotein (ORF1) gene, partial cds; and VP1 (ORF2)
and VP2 (ORF3) genes, complete cds.
ACCESSION MK762630
VERSION MK762630.1
KEYWORDS .
SOURCE Norovirus GII
ORGANISM Norovirus GII
Viruses; Riboviria; Orthornavirae; Pisuviricota; Pisoniviricetes;
Picornavirales; Caliciviridae; Norovirus; Norwalk virus.
REFERENCE 1 (bases 1 to 7507)
AUTHORS Barclay,L., Cannon,J.L., Wikswo,M.E., Phillips,A., Browne,H.,
Montmayeur,A.M., Tatusov,R.L., Burke,R.M., Hall,A.J. and Vinje,J.
TITLE Emergence and characterization of multiple viruses associated with
a novel GII.P16 polymerase in the United States, 2015-2018
JOURNAL Unpublished
REFERENCE 2 (bases 1 to 7507)
AUTHORS Barclay,L., Cannon,J.L., Heberlein-Larson,L.A., Montmayeur,A.M.,
Tatusov,R.L., Chhabra,P. and Vinje,J.
TITLE Direct Submission
JOURNAL Submitted (05-APR-2019) Division of Viral Diseases, Centers for
Disease Control and Prevention, 1600 Clifton Road NE, Atlanta, GA
30329, USA
COMMENT ##Assembly-Data-START##
Assembly Method :: Geneious v. R10; SPAdes v. 3.6
Sequencing Technology :: Illumina
##Assembly-Data-END##
FEATURES Location/Qualifiers
source 1..7507
/organism="Norovirus GII"
/mol_type="genomic RNA"
/strain="Broward1056"
/isolate="Hu/US/2015/GII.Pe-GII.4 Sydney/Broward1056"
/isolation_source="stool"
/host="Homo sapiens"
/db_xref="taxon:122929"
/country="USA"
/collection_date="15-Dec-2015"
/note="genotype: GII.Pe-GII.4 Sydney"
gene <1..5052
/gene="ORF1"
CDS <1..5052
/gene="ORF1"
/codon_start=1
/product="nonstructural polyprotein"
/protein_id="QBX91117.1"
/translation="NNDIAKSSSDGVFSNMAVTFKRALGARPKQPPPKEIPPRPPRPP
TPELVKKIPPPPPNGEDELVVSYNAKDGVSGLPELTTVRQPEETNTAFSVPPLNQRES
RDAKEPLTGTIIEMWDGEIYHYGLYVERGLILGVHKPPAAISLAKVELAPLSLFWRPV
YTPQYLISPDTLRRLHGESFPYTAFDNNCYAFCCWVLDLNDSWLSRRMIQRTTGFFRP
YQDWNRKPLPTMDDSKLKKVANIFLCTLSSLFTRPIKDIIGKLKPLNILNILATCDWT
FAGIVESLILLAELFGVFWTPPDVSAMIAPLLGDYELQGPEDLAVELVPIVMGGIGLV
LGFTKEKIGKMLSSAASTLRACKDLGAYGLEILKLVMKWFFPKKEEANELAMVRSIED
AVLDLEAIENNHMTTLLKDKDSLATYMRTLDLEEEKARKLSTKSASPDIVGTINSLLA
RIAAARSLVHRAKEELSSRPRPVVVMISGRPGIGKTHLARELAKKIATSLTGDQRVGL
IPRNGVDHWDAYKGERVVLWDDYGMSNPIHDALRLQELADTCPLTLNCDRIENKGKVF
DSDAIIITTNLANPAPLDYVNFEACSRRIDFLVYAEAPEVEKAKRDFPGQPDMWKNAF
SPDFSHIKLTLAPQGGFDKNGNTPHGKGVMKTLTTGSLIARASGLLHERLDEYELQGP
ALTTFNFDRNKILAFRQLAAENKYGLMDTMRVGKQLKDVKTMPDLKQALKNIAIKKCQ
IVYNGGTYTLEADGKGSVKVDKVQSATVQTNNELAGALHHLRCARIRYYVKCVQEALY
SIIQIAGAAFVTTRIAKRMNIQNLWSKPQVEDTEEMTNKDGCLKPKDDEEFVVSSDDI
RTEGKKGKNKSGRGKKHTAFSSKGLSDEEYDEYKRIREERNGKYSIEEYLQDRDRYYE
EVAIARATEEDFCEEEEAKIRQRIFRPTRKQRKEERTSLGLVTGSEIRKRNPEDFKPK
GKLWADDDRSVDYNEKLNFEAPPSIWSRIVNFGSGWGFWVSPSLFVTSTHVIPQGAKE
FFGVPIKQIQIHKSGEFCRLRFPKPIRTDVTGMILEEGAPEGTVATLLIKRPTGELMP
LAARMGTHATMKIQGRTVGGQMGMLLTGSNAKSMDLGTTPGDCGCPYIYKRGNDYVVI
GVHTAAARGGNTVICATQGSEGEATLEGGDSKGTYCGAPILGPGSAPKLSTKTKFWRS
STTPLPPGTYEPAYLGGKDPRVKGGPSLQQVMRDQLKPFTEPRGKPPRPNVLEAAKKT
IINVLEQTIDPPQKWSFAQACASLDKTTSSGHPHHMRKNDCWNGESFTGKLADQASKA
NLMFEEGKNMTPVYTGALKDELVKTDKVYGKIKKRLLWGSDLATMIRCARAFGGLMDE
LKAHCVTLPVRVGMNMNEDGPIIFEKHSRYRYHYDADYSRWDSTQQRDVLAAALEIMV
KFSPEPHLAQVVAEDLLSPSVMDVGDFQISISEGLPSGVPCTSQWNSIAHWLLTLCAL
SEVTDLSPDIIQANSLFSFYGDDEIVSTDIKLDPEKLTTKLKEYGLKPTRPDKTEGPL
VISENLDGLTFLRRTVTRDPAGWFGKLEQSSILRQMYWTRGPNHEDPFETMIPHSQRP
IQLMSLLGEAALHGPAFYSKISKLVIAELKEGGMDFYVPRQEPMFRWMRFSDLSTWEG
DRNLAPSFVNEDGVE"
mat_peptide <1..942
/gene="ORF1"
/product="p48"
mat_peptide 943..2040
/gene="ORF1"
/product="NTPase"
mat_peptide 2041..2577
/gene="ORF1"
/product="p22"
mat_peptide 2578..2976
/gene="ORF1"
/product="VPg"
mat_peptide 2977..3519
/gene="ORF1"
/product="Pro"
mat_peptide 3520..5049
/gene="ORF1"
/product="RdRp"
gene 5033..6655
/gene="ORF2"
CDS 5033..6655
/gene="ORF2"
/note="major capsid protein"
/codon_start=1
/product="VP1"
/protein_id="QBX91118.1"
/translation="MKMASSDANPSDGSAANLVPEVNNEVMALEPVVGAAIAAPVAGQ
QNVIDPWIRNNFVQAPGGEFTVSPRNAPGEILWSAPLGPDLNPYLSHLARMYNGYAGG
FEVQVILAGNAFTAGKVIFAAVPPNFPTEGLSPSQVTMFPHIVVDVRQLEPVLIPLPD
VRNNFYHYNQSNDPTIKLIAMLYTPLRANNAGDDVFTVSCRVLTRPSPDFDFIFLVPP
TVESRTKPFSVPVLTVEEMTNSRFPIPLEKLFTGPSSAFVVQPQNGRCTTDGVLLGTT
QLSPVNICTFRGDVTHITGSHNYTMNLASQNWNNYDPTEEIPAPLGTPDFVGKIQGVL
TQTTRTDGSTRGHKATVYTGSADFAPKLGRVQFETDTNHDFEANQNTKFTPVGVIQDG
STTHRNEPQQWVLPSYSGRNTHNVHLAPAVAPTFPGEQLLFFRSTMPGCSGYPNMDLD
CLLPQEWVQYFYQEAAPAQSDVALLRFVNPDTGRVLFECKLHKSGYVTVAHTGQHDLV
IPPNGYFRFDSWVNQFYTLAPMGNGTGRRRAV"
gene 6655..7461
/gene="ORF3"
CDS 6655..7461
/gene="ORF3"
/note="minor structural protein; small basic protein"
/codon_start=1
/product="VP2"
/protein_id="QBX91119.1"
/translation="MAGAFFAGLASDVLGSGLGSLINAGAGAINQKVEFENNRKLQQA
SFQFSSNLQQASFQHDKEMLQSQIETTKKLQQEMMKVKQAVLLEGGFSEADAARGAIN
APMTKALDWSGTRYWAPDARTTTYNAGRFSTPQPSGALPGRANLRDVVPARGSSSKSS
NSSTATSVYSNQTTSTRLGSTAGSGTSVSSLPSTARTRSWVEDQSRNLSPFMRGAHNI
SFVTPPSSRSSSQGTVSTVPKEVLDSWTGAFNTRRQPLFAHIRKRGESRA"
ORIGIN
1 aacaacgaca tcgcaaaatc ttcaagtgac ggtgtgtttt ctaacatggc tgtcactttt
61 aagcgggccc tcggggcgcg gcctaaacag ccgcccccga aggagatacc acccagaccc
121 ccacgaccac ccacaccaga attggtcaaa aagatccctc ctcccccacc caacggggag
181 gatgaactag tggtctctta caacgccaaa gatggcgttt ccggactgcc tgagctcacc
241 actgtcagac aaccggaaga aaccaacacg gcgttcagtg tccccccact caaccaaagg
301 gagagcaggg acgccaagga gccactaact ggaacaatta ttgaaatgtg ggatggagaa
361 atctaccatt acggcctgta cgtggaacga ggtcttatac ttggtgtgca caagccaccg
421 gcagccatca gccttgccaa ggttgagcta gcaccgctct ctttgttctg gagacctgta
481 tacacccccc agtatctcat ctctccagac acccttagga gattacatgg agagtccttc
541 ccctacactg catttgacaa caattgctac gccttttgtt gttgggtatt agacctaaac
601 gactcatggc taagcaggag aatgattcag agaacaacag gtttcttcag gccgtaccag
661 gactggaaca ggaaacccct ccccactatg gatgattcca aattaaagaa ggtagccaac
721 atattcttgt gcactttgtc ttcactattc accagaccca ttaaggacat aatagggaag
781 ttgaaacctc tcaacatcct taacattctg gctacatgtg attggacctt cgcaggcata
841 gtggaatctt taatactctt agcagaactc tttggagttt tctggacacc cccagatgtg
901 tctgcgatga tcgccccctt gctaggtgat tatgaactgc aaggacctga ggaccttgca
961 gtggagctgg tcccaatagt gatggggggg ataggtttgg tgctaggatt taccaaagag
1021 aaaattggaa agatgctatc atccgctgca tccactttaa gagcttgtaa agaccttggt
1081 gcatacggac tggaaatctt aaaattggtc atgaagtggt tcttcccaaa gaaagaggaa
1141 gcaaatgaac tggctatggt gagatccatc gaggatgcag tattagacct cgaggcaatt
1201 gaaaataacc acatgaccac cctactcaaa gacaaagaca gcttggcaac ctacatgaga
1261 acccttgacc ttgaggagga gaaagccaga aaactttcaa ccaaatctgc ttcacccgat
1321 attgtgggca caatcaactc tcttctggca agaatcgctg ctgcacgctc cctagtgcat
1381 cgggcgaaag aagagctctc cagcaggccg agacctgtcg ttgtgatgat atcgggaaga
1441 ccagggatag ggaaaactca tcttgccagg gagctggcca agaagatcgc gacctccctc
1501 acaggggacc agcgtgtggg tcttatccca cgcaatggtg tcgatcactg ggacgcatac
1561 aagggcgaaa gagttgtcct atgggacgac tatggaatga gtaaccccat ccatgatgcc
1621 ctcaggttgc aggagcttgc tgacacttgc cccctcacgc taaattgtga cagaattgag
1681 aacaaaggga aagtctttga cagcgatgcc ataatcatta ccaccaatct ggccaaccca
1741 gcaccactgg attatgtcaa ctttgaagcg tgctcgagac gtattgactt cctcgtgtac
1801 gcagaagccc ctgaggtgga gaaggcaaag cgcgacttcc caggtcaacc tgacatgtgg
1861 aagaacgctt tcagtcctga cttctcacac ataaaactga cattggctcc acagggtggt
1921 tttgacaaga acggcaacac cccgcatgga aaaggggtca tgaagaccct caccactggt
1981 tccctcatcg cccgagcatc agggttactc catgagaggc tagatgaata tgaactgcaa
2041 ggcccagccc ttaccacttt caactttgac cgaaacaaga tacttgcttt tagacagctt
2101 gctgccgaaa acaagtatgg gctgatggac acaatgagag tgggaaaaca gctcaaggat
2161 gtcaagacca tgccagacct caaacaagcg ctcaagaaca tcgcgatcaa gaagtgtcag
2221 atagtgtaca atggtggcac ctacacactt gaggccgatg gcaagggtag tgtgaaagtt
2281 gacaaagtgc aaagtgccac tgtgcagacc aacaatgaac tagccggtgc cctacaccac
2341 ctaaggtgcg ccagaatcag atactatgtt aagtgcgtcc aggaggcact gtattccatc
2401 atccaaatcg ctggggctgc attcgtcacc acgcgcatcg ctaagcgcat gaatatacag
2461 aatctctggt ccaagccaca ggtggaagac acagaagaga tgaccaacaa agatggttgc
2521 ctaaagccca aagatgatga agagtttgtc gtctcatccg acgacatcag aactgagggc
2581 aagaaaggga agaacaagtc cggccgtggc aagaagcaca cagccttttc aagcaaaggg
2641 ctcagtgatg aggagtacga tgagtacaag agaatcagag aagaaaggaa tggtaagtac
2701 tccatagaag agtaccttca ggacagagac aggtactacg aggaggtggc cattgccagg
2761 gcgaccgaag aggacttctg tgaagaagaa gaggccaaaa tccggcagag aatttttaga
2821 ccaacaagga aacaacgcaa agaagagagg acctctctcg gcttggtcac aggctctgaa
2881 atcaggaaga gaaacccaga agacttcaaa cccaagggaa agctgtgggc tgatgatgac
2941 agaagtgttg actacaacga gaaactcaac tttgaggccc caccaagtat ttggtcgcgg
3001 atagtcaact ttggttcagg ctggggtttc tgggtctccc ccagtctgtt tgtaacatca
3061 acccatgtca taccccaagg tgcaaaagag ttcttcggag tccctatcaa gcaaatccag
3121 atacacaaat caggtgaatt ctgccggttg agattcccaa agccaatcag aactgatgtg
3181 acgggcatga ttctagaaga aggtgcgccc gaggggaccg tagccacact gctcatcaag
3241 agaccaactg gagagctcat gcctctggca gccagaatgg ggacccatgc aaccatgaaa
3301 attcaggggc gcacagttgg agggcaaatg ggtatgctcc tgacaggatc caacgccaag
3361 agtatggacc taggcacaac accaggcgac tgcggctgcc cctacatcta caagaggggg
3421 aatgactacg tggtcatagg agtccatact gccgctgccc gtggaggaaa cactgtcata
3481 tgtgccaccc aggggagtga gggagaagcc acacttgaag gaggtgacag taaagggaca
3541 tactgtggcg caccaatcct gggcccaggg agcgctccga agctcagtac caagactaag
3601 ttttggagat catccacaac accacttcca cctggcacct acgaaccagc ctatctcggt
3661 ggcaaagacc ccagagtcaa aggtggccct tcattgcaac aagttatgag ggaccagcta
3721 aagccattca cagaacccag aggcaaacca ccaagaccaa atgtgttgga agctgccaag
3781 aaaaccatca tcaatgtact tgagcaaaca attgatccac cccaaaaatg gtcatttgcg
3841 caagcttgcg catcccttga caaaaccacc tccagcggcc acccgcacca catgcggaaa
3901 aacgattgtt ggaatgggga gtccttcaca ggaaaattgg ctgatcaagc ctccaaggcc
3961 aacctaatgt ttgaagaggg aaagaacatg accccagtct acacaggtgc acttaaagat
4021 gagttggtaa agaccgataa agtttatggt aagatcaaga agaggcttct gtggggttca
4081 gatctggcga ccatgatacg gtgcgcccga gcttttggag gccttatgga tgaactcaag
4141 gcacactgtg tcacacttcc tgtcagagtt ggtatgaata tgaatgagga tggccccatc
4201 atctttgaga agcactccag atatagatat cactatgatg ctgattattc ccggtgggac
4261 tcaacacaac aaagggatgt gctagcagca gcactagaga tcatggttaa gttctctcca
4321 gaaccacacc tggcccaggt tgttgcggaa gacctccttt cccctagcgt gatggatgta
4381 ggtgactttc aaatatcaat aagtgagggt cttccctctg gggtaccctg tacctcccaa
4441 tggaattcca tcgcccactg gctcctcact ctttgtgcac tctctgaagt tacggacctg
4501 tcccctgaca tcattcaggc caactccctt ttctccttct atggtgatga tgagattgtg
4561 agcacagaca taaagttgga cccagagaag ctgacgacaa aactcaagga gtacgggctg
4621 aaaccaaccc gccccgacaa aactgaagga ccccttgtca tctctgaaaa cctggatggc
4681 ctgacattcc tccggagaac tgtgacccgt gatccagctg gctggtttgg aaaattggaa
4741 caaagttcaa ttctcagaca aatgtactgg accaggggtc ccaaccatga agatccattt
4801 gaaacaatga taccacactc ccaaagaccc atacaattga tgtccttgct gggcgaggct
4861 gcactccacg gcccggcatt ttatagcaaa attagcaaat tagtcattgc agagttgaag
4921 gaaggtggca tggattttta cgtgcccagg caagagccaa tgttcagatg gatgaggttc
4981 tcagatctga gcacgtggga gggcgatcgc aatctggctc ccagttttgt gaatgaagat
5041 ggcgtcgagt gacgccaacc catctgatgg gtccgcagcc aacctcgtcc cagaggtcaa
5101 caatgaggtt atggctctgg agcccgttgt tggtgccgcc attgcggcac ctgtagcggg
5161 ccaacaaaac gtaattgacc cctggattag gaacaatttt gtacaagccc ctggtggaga
5221 atttacagtg tcccctagaa atgctccagg tgaaatacta tggagcgcgc ccttgggccc
5281 cgacctaaat ccctacctat cccatttggc cagaatgtac aatggttatg caggtggttt
5341 tgaagtgcag gtaattctcg cggggaacgc gttcaccgcc gggaaggtca tatttgcagc
5401 agtcccacca aattttccaa ctgaaggctt gagccccagc caggttacta tgttccccca
5461 tatagtagta gatgttaggc aactagaacc tgtgttgatt cccttacccg atgttaggaa
5521 taatttctat cattataatc aatcaaatga ccccaccatt aagttgatag caatgttgta
5581 tacaccactt agggctaata atgctgggga tgatgtcttc acagtttctt gccgagttct
5641 caccagacca tcccccgatt ttgatttcat atttctagtg ccacccacag ttgagtcaag
5701 aactaaacca ttctctgtcc cagttttaac tgttgaggag atgaccaact caagattccc
5761 cattcctttg gaaaagctgt tcacgggtcc cagcagtgcc tttgttgtcc aaccacaaaa
5821 cggcaggtgc acgactgatg gcgtgctcct aggcaccacc caattgtctc ctgtcaacat
5881 ctgcaccttc agaggagatg tcacccacat cacaggtagt cataactaca caatgaattt
5941 ggcttctcaa aattggaaca attacgaccc aacagaagaa atcccagccc ctctaggaac
6001 tccagacttt gtggggaaga ttcaaggtgt gctcacccag accacaagga cagatggctc
6061 aacacgcggc cacaaagcca cagtgtacac tgggagcgcc gactttgctc caaaactggg
6121 tagagttcaa tttgaaactg acacaaacca tgattttgaa gctaaccaaa acacaaagtt
6181 caccccagtc ggtgtcatcc aagatggtag caccacccac cgaaatgaac cccaacaatg
6241 ggtgctccca agttactcag gcagaaacac tcacaatgtg catctggccc ccgctgtagc
6301 ccccactttt ccgggtgagc aacttctctt cttcagatct accatgcccg gatgcagcgg
6361 gtaccccaac atggatttgg actgtctact cccccaggaa tgggtgcagt acttctacca
6421 agaggcagcc ccagcacaat ctgatgtggc tctgctaaga tttgtgaatc cagatacagg
6481 tagggttttg tttgagtgta agctccataa atcaggctat gttacagtgg ctcacactgg
6541 ccaacatgat ttggttatcc cccccaatgg ttattttaga tttgattcct gggtcaacca
6601 gttctacacg cttgccccca tgggaaatgg aacggggcgt agacgtgctg tataatggct
6661 ggagctttct ttgctggatt ggcatctgat gtccttggct ctggacttgg ttcccttatc
6721 aatgctgggg ctggggccat caaccagaaa gttgagtttg aaaacaacag aaaattgcaa
6781 caagcatcct tccaatttag cagcaatcta caacaggctt ccttccaaca tgacaaagag
6841 atgctccaat cacaaattga gaccaccaaa aagttacaac aggaaatgat gaaagtcaag
6901 caggcagtgc tcctagaggg tgggttctca gaggcggatg cagcccgcgg ggcaatcaac
6961 gcccccatga caaaagcttt ggactggagc gggacaaggt actgggctcc tgatgctagg
7021 actacaacat acaatgcagg ccgcttttcc acccctcaac catcgggggc actgccagga
7081 agagctaatc ttagggatgt tgtccctgct cggggttcct ccagtaaatc ttctaactct
7141 tctactgcta cttctgtgta ctcaaatcaa actacttcaa cgagacttgg ttctacagct
7201 ggttctggca ccagtgtctc gagcctcccg tcaactgcaa ggactaggag ctgggttgag
7261 gatcaaagta ggaatttgtc acctttcatg aggggggccc acaacatatc gtttgtcacc
7321 ccaccatcta gcagatcctc tagccaaggc acagtctcaa ccgtgcccaa agaggttttg
7381 gactcctgga ctggcgcttt caacacgcgc aggcagccac tcttcgctca cattcgtaag
7441 cgaggggagt cacgggcgta atgtgaaaag acaaaattga ttatcttacc ttttctttag
7501 tgtcttt
//