Typing tool
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Typing tool
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Complete norovirus genomes
| MK762623 | GII.4 Sydney | |
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| GII.P4 New Orleans |
ORF1: 1..5089
ORF2: 5070..6692
ORF3: 6692..7498
LOCUS MK762623 7560 bp RNA linear VRL 13-APR-2019
DEFINITION Norovirus GII isolate Hu/US/2017/GII.P4 NO-GII.4 Sydney/Jackson0853
nonstructural polyprotein (ORF1) gene, partial cds; and VP1 (ORF2)
and VP2 (ORF3) genes, complete cds.
ACCESSION MK762623
VERSION MK762623.1
KEYWORDS .
SOURCE Norovirus GII
ORGANISM Norovirus GII
Viruses; Riboviria; Orthornavirae; Pisuviricota; Pisoniviricetes;
Picornavirales; Caliciviridae; Norovirus; Norwalk virus.
REFERENCE 1 (bases 1 to 7560)
AUTHORS Barclay,L., Cannon,J.L., Wikswo,M.E., Phillips,A., Browne,H.,
Montmayeur,A.M., Tatusov,R.L., Burke,R.M., Hall,A.J. and Vinje,J.
TITLE Emergence and characterization of multiple viruses associated with
a novel GII.P16 polymerase in the United States, 2015-2018
JOURNAL Unpublished
REFERENCE 2 (bases 1 to 7560)
AUTHORS Barclay,L., Cannon,J.L., Selvarangan,R., Montmayeur,A.M.,
Tatusov,R.L., Chhabra,P. and Vinje,J.
TITLE Direct Submission
JOURNAL Submitted (05-APR-2019) Division of Viral Diseases, Centers for
Disease Control and Prevention, 1600 Clifton Road NE, Atlanta, GA
30329, USA
COMMENT ##Assembly-Data-START##
Assembly Method :: Geneious v. R10; SPAdes v. 3.6
Sequencing Technology :: Illumina
##Assembly-Data-END##
FEATURES Location/Qualifiers
source 1..7560
/organism="Norovirus GII"
/mol_type="genomic RNA"
/strain="Jackson0853"
/isolate="Hu/US/2017/GII.P4 NO-GII.4 Sydney/Jackson0853"
/isolation_source="stool"
/host="Homo sapiens"
/db_xref="taxon:122929"
/country="USA"
/collection_date="02-Feb-2017"
/note="genotype: GII.P4 New Orleans-GII.4 Sydney"
gene <1..5089
/gene="ORF1"
CDS <1..5089
/gene="ORF1"
/codon_start=2
/product="nonstructural polyprotein"
/protein_id="QBX91096.1"
/translation="SSDASAAAVANSNNDTAKSSSDGVLSSMAVTFKRALGARPKQPP
PREKPQRPPRPPTPELVKNIPPPPPNGEDEIVVSYSVKDGVSGLPDLSTVRQPEESNT
AFSVPPLNQRENRDAKEPLTGTILEMWDGEIYHYGLYVERGLVLGVHRPPAAISLAKV
ELAPLSLYWRPVYTPQYLISPDTLKKLSGETFPYTAFDNNCYAFCCWVLDLNDSWLSR
RMIQRTTGFFRPYQDWNRKPLPTMDDSKIKKVANIFLCALSSLFTRPIKDIIGKIRPL
NILNILASCDWTFAGIVESLILLAELFGVFWTPPDVSAMIAPLLGDYELQGPEDLAVE
LVPVVMGGIGLVLGFTKEKIGKMLSSAASTLRACKDLGAYGLEILKLVMKWFFPKKEE
ANELAIVRSIEDAVLDLEAIENNHMTTLLKDKDSLATYMRTLDLEEEKARKLSTKSAS
PDIVGTINALLARIAAARSLVHRAKEELSSRPRPVVLMISGRPGIGKTHLAREVAKRI
AASLTGDQRVGLIPRNGVDHWDAYKGERVVLWDDYGMSNPIHDALRLQELADTCPLTL
NCDRIENKGKVFDSDVIIITTNLANPAPLDYVNFEACSRRIDFLVYAEAPEVEKAKRD
FPGQPDMWKNAFSSDFSHIKLALAPQGGFDKNGNTPHGKGVMKTLTTGSLIARASGLL
HERLDEFELQGSALTTFNFDRNKVLAFRQLAAENKYGLMDTMRVGKQLKDVRTMPELK
QALKNVSIKKCQIVYSGCTYMLESDGKGNVKVDRIQSAAVQTNNELAGALHHLRCARI
RYYVKCVQEALYSIIQIAGAAFVTTRIAKRMNIQDLWSKPQVENTEETTSRDGCPKPK
DDEEFVISSDDIKTEGKKGKNKTGRGKKHTAFSSKGLSDEEYDEYKRIREERNGKYSI
EEYLQDRDKYYEEVAIARATEEDFCEEEEAKIRQRIFRPTRKQRKEERVSLGLVTGSE
IRKRNPDDFKPKGKLWADDDRSVDYNEKLSFEAPPSIWSRIVNFGSGWGFWVSPSLFI
TSTHVIPQGAKEFFGVPIKQIQVHKSGEFCRLRFPKPIRTDVTGMILEEGAPEGTVVT
LLIKRSTGELMPLAARMGTHATMKIQGRTVGGQMGMLLTGSNAKSMDLGTTPGDCGCP
YIYKRGNDYVVIGVHTAAARGGNTVICATQGSEGEATLEGGDNKGTYCGAPILGPGSA
PTLSTKTKFWRSSTASLPPGTYEPAYLGGKDPRVKGGPSLQQVMREQLKPFTEPRGKP
PKPSVLEAAKKTIINVLEQTIDPPEKWSFAQACASLDKTTSSGHPHHMRKNDCWNGES
FTGKLADQASKANLMFEEGKNVTPVYTAALKDELVKTDKIYGKIKKRLLWGSDLATMI
RCARAFGGLMDELKAHCVTLPIRVGMNMNEDGPIIFERHSRYTYHYDADYSRWDSTQQ
RAVLAAALEIMVKFSPEPHLAQVVAEDLLSPSVVDVGDFTISINEGLPSGVPCTSQWN
SIAHWLLTLCALSEVTNLSPDTIQANSLFSFYGDDEIVSTDIRLDPEKLTAKLREYGL
KPTRPDKTEGPLVISEDLNGLTFLRRTVTRDPAGWFGKLEQSSILRQIYWTRGPNHGD
PSETMIPHSQRPIQLMSLLGEAALHGPAFYSKISKLVIAELKEGGMDFYVPRQEPMFR
WMRFSDLSTWEGDRNLAPSFVNEDGVE"
mat_peptide <1..979
/gene="ORF1"
/product="p48"
mat_peptide 980..2077
/gene="ORF1"
/product="NTPase"
mat_peptide 2078..2614
/gene="ORF1"
/product="p22"
mat_peptide 2615..3013
/gene="ORF1"
/product="VPg"
mat_peptide 3014..3556
/gene="ORF1"
/product="Pro"
mat_peptide 3557..5086
/gene="ORF1"
/product="RdRp"
gene 5070..6692
/gene="ORF2"
CDS 5070..6692
/gene="ORF2"
/note="major capsid protein"
/codon_start=1
/product="VP1"
/protein_id="QBX91097.1"
/translation="MKMASSDANPSDGSAANLVPEVNNEVMALEPVVGAAIAAPVAGQ
QNVIDPWIRNNFVQAPGGEFTVSPRNAPGEILWSAPLGPDLNPYLSHLARMYNGYAGG
FEVQVILAGNAFTAGKVIFAAVPPNFPTEGLSPSQVTMFPHIVVDVRQLEPVLIPLPD
VRNNFYHYNQSNDPTIKLIAMLYTPLRANNAGDDVFTVSCRVLTRPSPDFDFIFLVPP
TVESRTKPFSVPVLTVEEMTNSRFPIPLEKLFTGPSSAFVVQPQNGRCTTDGVLLGTT
QLSPVNICTFRGDVTHITGSRNYTMNLASQNWNNYDPTEEIPAPLGAPDFVGKIQGML
TQTTRADGSTRGHKATVYTGSADFAPKLGRVQFETDTDRDFEANQNTKFTPVGVIQDG
STTHRNEPQQWVLPSYSGRNTHNVHLAPAVAPTFPGEQILFFRSTMPGCSGYPNMDLD
CLLPQEWVQYFYQEAAPAQSDVALLRFVNPDTGRVLFECKLHKSGYVTVAHTGQHDLV
IPPNGYFRFDSWVNQFYTLAPMGNGTGRRRVV"
gene 6692..7498
/gene="ORF3"
CDS 6692..7498
/gene="ORF3"
/note="minor structural protein; small basic protein"
/codon_start=1
/product="VP2"
/protein_id="QBX91098.1"
/translation="MAGAFFAGLASDVLGSGLGSLINAGAGAINQKVDFENNRKLQQA
SFQFSSNLQQASFQHDKEMLQAQIEATKKLQQEMMKVKQALLLEGGFSETDAARGAIN
APMTKALDWSGTRYWAPDARTTTYNAGRFSTPQPSGALPGRANLRDTVPARGSSSKSP
NPSTATSVYSNQTTSTRLGSTAGSGTSVSSLPSTARTRSWVEDQSRNLSPFMRGAHNI
SFVTPPSSKSSSQGTVSTVPKEVLDSWTGAFNTRRQPLFAHIRKRGESRA"
ORIGIN
1 gtctagcgac gcttccgctg ccgctgttgc taacagcaac aacgacaccg caaaatcttc
61 aagtgacgga gtgctttcta gcatggctgt cacttttaaa cgagccctcg gggcgcggcc
121 taaacagcca cccccgaggg aaaaaccaca aagacccccg cgaccaccta ctccagaact
181 ggttaagaat atcccccctc ccccacccaa cggagaggat gaaatagtgg tctcttatag
241 tgtcaaagat ggtgtttccg gcttgcctga cctttctacc gtcaggcaac cggaagagtc
301 taacacggcc ttcagtgtcc ctccactcaa tcagagggag aatagagatg ctaaggagcc
361 actcactggg acaatcctgg aaatgtggga cggggaaatc taccattatg gcctgtatgt
421 ggagcgaggt cttgtactag gtgtgcacag accgccagct gccatcagcc ttgctaaggt
481 tgagctggca ccactctcct tgtactggag acctgtgtac actcctcagt acctcatctc
541 tccagacact ctcaagaaat tgtccggaga gacgttcccc tatacagcct ttgataacaa
601 ctgttatgcc ttttgttgct gggttctgga cctaaatgac tcgtggctga gtagaaggat
661 gatccagaga acgactggtt tcttcaggcc ctaccaggac tggaatagga aaccccttcc
721 tactatggat gactccaaaa taaagaaggt agctaacata tttctgtgtg ccctgtcctc
781 gctattcacc agacccataa aagacataat agggaagata aggcctctta atatcctcaa
841 catcttggcc tcatgtgact ggaccttcgc gggtatagtg gagtctctga tactcttggc
901 agaactcttt ggagtcttct ggacaccccc agatgtgtct gcgatgattg cccccttact
961 tggtgactac gagctacaag gacctgagga ccttgcagtg gagctcgtcc ccgtggtgat
1021 ggggggaatt ggtttggtgc taggattcac caaagagaag attgggaaaa tgttgtcatc
1081 tgctgcgtcc actctgagag cttgcaaaga ccttggtgca tatgggctag agatcctaaa
1141 gttagtcatg aagtggttct tcccaaagaa ggaggaggca aatgagctgg ctatagtgag
1201 gtccattgag gacgcagtcc tggatctcga ggcaattgaa aacaatcata tgaccacctt
1261 gcttaaagat aaagacagcc tggcaaccta catgaggaca cttgaccttg aagaggagaa
1321 agccaggaaa ctctcaacca agtctgcctc acctgacatc gtgggtacaa tcaacgccct
1381 cctagcgaga attgctgccg cacgttctct ggtgcatcga gcgaaggagg agctttccag
1441 cagaccaaga cctgtggtgt tgatgatatc aggcagacca ggaataggga agacccacct
1501 cgctagggaa gtggctaaga gaatcgcagc ctcccttaca ggggaccagc gtgtgggcct
1561 cattccacgc aatggtgtcg accattggga tgcgtacaag ggggagaggg tcgtcctgtg
1621 ggacgattat ggaatgagca accctattca cgatgccctc aggcttcaag aactcgctga
1681 cacttgtccc ctcactctga actgtgacag gattgaaaat aaaggaaagg tctttgacag
1741 cgatgtcatc attatcacca ctaacctggc caacccagca ccactggact atgtcaactt
1801 tgaagcatgc tcgaggcgca ttgacttcct cgtgtatgca gaagcccctg aagtcgaaaa
1861 ggcgaagcgt gacttcccag gccagcctga catgtggaag aacgctttca gttctgattt
1921 ctcacacata aaactagcac tggccccaca aggtggtttc gataagaacg gaaacacccc
1981 acacggaaag ggcgtcatga agaccctcac cactggctcc cttattgccc gggcatcagg
2041 gctactccat gagaggttgg atgaatttga actgcagggt tcggctctta ccaccttcaa
2101 tttcgaccgc aataaagtgc ttgcctttag acagcttgct gctgaaaaca agtatggatt
2161 gatggacaca atgagggttg ggaaacagct caaggatgtc agaaccatgc cagaactcaa
2221 acaagcactc aagaatgtct caatcaagaa gtgccaaata gtgtatagtg gttgcactta
2281 catgcttgag tctgatggca agggcaatgt gaaagttgac agaatccaaa gtgccgccgt
2341 gcagaccaac aatgagctgg ctggtgccct acaccacttg aggtgcgcca gaatcagata
2401 ctatgtcaag tgtgtccagg aagccctgta ttccatcatc caaatcgctg gggctgcatt
2461 tgtcaccacg cgcattgcca agcgcatgaa catacaagac ctatggtcca agccacaagt
2521 ggaaaacaca gaggagacta ccagcaggga cgggtgccca aaacctaagg atgatgagga
2581 gttcgtcatt tcatccgacg acatcaaaac tgagggcaag aaagggaaga acaagactgg
2641 ccgtggcaag aagcacacag cattttcaag caaaggcctc agtgatgaag agtatgatga
2701 atacaagagg attagagaag aaaggaatgg caagtactct atagaagaat acctccagga
2761 cagggacaaa tactatgagg aggtggccat tgccagggcg actgaggaag acttctgtga
2821 agaggaggag gccaagatcc ggcaaaggat ctttagacca acaaggaaac aacgcaagga
2881 ggaaagagtc tctcttggcc tggtcacagg ctctgaaatt aggaaaagaa acccagatga
2941 cttcaaaccc aaggggaagt tgtgggctga cgatgacagg agtgtggact acaatgagaa
3001 actcagcttt gaggccccac caagcatttg gtcgagaata gtcaactttg gttcaggctg
3061 gggattctgg gtctccccca gtctgttcat aacatcaacc catgtcatac cccaaggcgc
3121 aaaggagttc tttggagtcc ccatcaaaca aatacaggtg cacaagtcag gcgagttctg
3181 tcgcttgaga ttccctaaac caatcaggac tgatgtgacg ggcatgatct tggaagaagg
3241 cgcacctgag ggcaccgtgg tcacactact catcaaaagg tccactgggg aactcatgcc
3301 cctagcagct aggatgggga cccatgcgac catgaagatc caagggcgca ctgttggagg
3361 ccagatgggc atgcttctga cagggtccaa tgccaagagc atggacctgg gtactacacc
3421 aggtgattgt ggctgcccct acatctacaa gagaggtaat gactatgtgg tcattggagt
3481 ccacacggct gccgcacgtg ggggaaacac tgtcatatgt gccacccaag ggagtgaagg
3541 ggaggctacg cttgagggtg gtgacaacaa agggacatac tgtggtgcac caatcctagg
3601 cccagggagt gccccaactc ttagcaccaa gaccaaattc tggagatcgt ccacagcatc
3661 acttccacct ggcacctatg aaccagccta ccttggtggc aaggacccta gagtcaaggg
3721 tggcccttca ctgcagcaag tcatgaggga acagttgaag ccgttcacag agcccagggg
3781 caagccacca aaaccaagtg tattagaagc tgccaagaag accatcatta acgtccttga
3841 gcaaacaatt gatccacctg agaaatggtc gttcgcacaa gcttgcgcgt cccttgacaa
3901 gaccacttcc agtggccatc cgcaccacat gcggaaaaac gactgctgga acggggagtc
3961 cttcacaggc aagctggcag accaggcttc caaggccaac ctgatgtttg aagaagggaa
4021 gaacgtgacc ccagtctaca cagctgcact caaggatgag ttagttaaaa ctgacaaaat
4081 ttatggtaag atcaagaaga ggcttctctg gggctcggat ttggcaacca tgattcggtg
4141 tgctcgagca ttcggaggcc taatggatga actcaaagcg cactgtgtca cactccccat
4201 tagagttggc atgaatatga atgaggatgg ccccatcatc ttcgagaggc attccaggta
4261 cacgtaccac tacgatgctg actactctcg gtgggattca acacaacaga gagccgtgtt
4321 ggcagcagct ctagaaatca tggttaaatt ctccccagaa ccacatttgg ctcaggtagt
4381 cgcggaagac cttctttccc ccagtgtggt ggacgtgggc gacttcacaa tatcaatcaa
4441 tgagggtctt ccctctgggg tgccctgcac ctcccaatgg aactccatcg cccactggct
4501 tctcactctc tgtgcgctct ctgaagtcac aaacctgtct cctgatacca tacaggctaa
4561 ttccctcttc tctttttatg gtgatgatga aattgttagc acagacataa gattggaccc
4621 agagaaactg acagcaaaac tcagagaata tgggttaaaa ccaacccgcc ctgacaaaac
4681 tgaaggaccc cttgtcatct ctgaagacct gaatggtcta actttcctgc ggagaactgt
4741 gacccgcgac ccagctggtt ggtttggaaa actggagcag agttcaatac tcaggcaaat
4801 ctactggact aggggtccca accatggaga cccatctgaa acaatgattc cacactccca
4861 aagacccata caattgatgt ccctactggg ggaggccgct ctccacggcc cagcatttta
4921 cagcaaaatc agcaaattgg tcattgcaga gctaaaagaa ggtggtatgg atttttacgt
4981 gcccagacaa gagccaatgt tcagatggat gagattctca gatctgagca cgtgggaggg
5041 cgatcgcaat ctggctccca gctttgtgaa tgaagatggc gtcgagtgac gccaacccat
5101 ctgatgggtc cgcagccaac ctcgtcccag aggtcaacaa tgaggtcatg gctctggagc
5161 ccgttgttgg tgccgccatt gcggcacctg tagcgggcca acaaaatgta attgacccct
5221 ggattagaaa caattttgta caagcccctg gtggagagtt tacagtgtcc cctagaaacg
5281 ctccaggtga aatactatgg agcgcgccct taggccctga tctaaatccc tacctatccc
5341 atttggccag aatgtataat ggttatgcag gtggttttga agtgcaggta attctcgcgg
5401 ggaacgcgtt caccgccggg aaggtcatat ttgcagcagt cccaccaaat tttccaactg
5461 aaggattgag ccccagccag gtcactatgt tcccccatat agtagtagat gttaggcaac
5521 tagaacctgt gttgattccc ctacccgatg ttaggaataa tttctaccat tacaaccaat
5581 caaatgaccc caccattaag ttgatagcaa tgttgtatac accacttagg gccaataatg
5641 ccggggacga tgtcttcaca gtttcttgcc gagttctcac aagaccatcc cccgattttg
5701 atttcatatt tttagtgcca cccacagttg agtcaagaac taaaccattc tctgtcccag
5761 ttctaactgt tgaggagatg accaattcaa gattccccat ccctttggaa aagttgttca
5821 cgggtcccag cagtgccttt gttgttcaac cacaaaacgg caggtgcacg actgatggcg
5881 tgctcctagg caccacccaa ctgtctcctg tcaacatctg caccttcaga ggggatgtca
5941 cccatatcac aggcagtcgt aattacacaa tgaatttggc ttctcaaaat tggaacaatt
6001 atgacccaac agaagaaatc ccagcccctc taggagctcc agactttgtg gggaagatcc
6061 aaggcatgct cacccaaacc acgagggctg atggttcaac acgcggccac aaagccacag
6121 tgtacactgg gagcgccgac tttgctccaa aactgggtag agtccaattt gaaactgaca
6181 cagaccgtga ttttgaagct aaccaaaata caaagttcac cccagtcggt gtcatccaag
6241 atggtagcac cacccaccga aatgaacccc aacagtgggt gctcccaagt tactcaggca
6301 gaaatactca taatgtgcat ttggcccccg ctgtagcccc cacttttccg ggtgagcaaa
6361 ttctcttctt cagatccacc atgcccggat gcagcgggta tcccaacatg gatttggact
6421 gtctgctccc ccaggaatgg gtgcagtact tctaccaaga ggcagcccca gcacaatctg
6481 atgtggctct gctaagattt gtgaatccag atacaggtag ggttttgttt gagtgtaagc
6541 ttcataaatc aggctatgtt acagtggctc acactggcca acatgatttg gttatccccc
6601 ccaatggtta ttttaggttt gattcttggg tcaaccagtt ctacacgctt gcccccatgg
6661 gaaatggaac ggggcgtaga cgtgtagtat aatggctgga gctttctttg ctggattggc
6721 atctgatgtc cttggctctg gacttggttc cctcatcaat gctggggctg gggccatcaa
6781 ccaaaaagtt gattttgaaa ataacagaaa attacaacag gcatccttcc aatttagcag
6841 caatctgcaa caggcttcct ttcaacatga caaagagatg ctccaagcac aaattgaggc
6901 caccaaaaag ctacaacagg aaatgatgaa agttaagcag gcattgctcc tagagggtgg
6961 gttctctgag acagatgcag cccgcggggc aattaacgct cccatgacaa aagctttgga
7021 ctggagcggg acaaggtact gggctcccga tgctaggact acaacatata atgcaggccg
7081 cttttccacc cctcaaccat cgggggcact gccaggaaga gctaatctta gggatactgt
7141 ccctgctcgg ggttcctcta gtaaatcccc taacccttct actgccactt ctgtgtactc
7201 aaatcaaacc acttcaacga gacttggttc tacagctggt tctggcacca gtgtctcgag
7261 cctcccgtca actgcaagga ctaggagctg ggttgaggat caaagtagga atttgtcacc
7321 tttcatgagg ggggcccaca acatatcgtt tgtcacccca ccatctagca aatcctctag
7381 ccaaggcaca gtctcaaccg tgcctaaaga ggttttggac tcctggactg gcgctttcaa
7441 cacgcgcaga cagcctctct tcgctcacat tcgtaagcga ggggagtcac gggcgtaatg
7501 tgaaaagaca aaattgatta tctttctctc tttttctttc tttagtgtct tctaaaacaa
//