Typing tool
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Typing tool
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Complete norovirus genomes
| MK762622 | GII.4 Sydney | |
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| GII.P4 New Orleans |
ORF1: 1..5092
ORF2: 5073..6695
ORF3: 6695..7501
LOCUS MK762622 7547 bp RNA linear VRL 13-APR-2019
DEFINITION Norovirus GII isolate Hu/US/2017/GII.P4 NO-GII.4 Sydney/Jackson0849
nonstructural polyprotein (ORF1) gene, partial cds; and VP1 (ORF2)
and VP2 (ORF3) genes, complete cds.
ACCESSION MK762622
VERSION MK762622.1
KEYWORDS .
SOURCE Norovirus GII
ORGANISM Norovirus GII
Viruses; Riboviria; Orthornavirae; Pisuviricota; Pisoniviricetes;
Picornavirales; Caliciviridae; Norovirus; Norwalk virus.
REFERENCE 1 (bases 1 to 7547)
AUTHORS Barclay,L., Cannon,J.L., Wikswo,M.E., Phillips,A., Browne,H.,
Montmayeur,A.M., Tatusov,R.L., Burke,R.M., Hall,A.J. and Vinje,J.
TITLE Emergence and characterization of multiple viruses associated with
a novel GII.P16 polymerase in the United States, 2015-2018
JOURNAL Unpublished
REFERENCE 2 (bases 1 to 7547)
AUTHORS Barclay,L., Cannon,J.L., Selvarangan,R., Montmayeur,A.M.,
Tatusov,R.L., Chhabra,P. and Vinje,J.
TITLE Direct Submission
JOURNAL Submitted (05-APR-2019) Division of Viral Diseases, Centers for
Disease Control and Prevention, 1600 Clifton Road NE, Atlanta, GA
30329, USA
COMMENT ##Assembly-Data-START##
Assembly Method :: Geneious v. R10; SPAdes v. 3.6
Sequencing Technology :: Illumina
##Assembly-Data-END##
FEATURES Location/Qualifiers
source 1..7547
/organism="Norovirus GII"
/mol_type="genomic RNA"
/strain="Jackson0849"
/isolate="Hu/US/2017/GII.P4 NO-GII.4 Sydney/Jackson0849"
/isolation_source="stool"
/host="Homo sapiens"
/db_xref="taxon:122929"
/country="USA"
/collection_date="21-Jan-2017"
/note="genotype: GII.P4 New Orleans-GII.4 Sydney"
gene <1..5092
/gene="ORF1"
CDS <1..5092
/gene="ORF1"
/codon_start=2
/product="nonstructural polyprotein"
/protein_id="QBX91093.1"
/translation="ASSDASAAAVANSNNDTAKSSSDGVLSSMAVTFKRALGARPKQP
PPREKPQRPPRPPTPELVKNIPPPPPNGEDEIVVSYSVKDGVSGLPDLSTVRQPEESN
TAFSVPPLNQRENRDAKEPLTGTILEMWDGEIYHYGLYVERGLVLGVHKPPAAISLAK
VELAPLSLYWRPVYTPQYLISPDTLKKLSGETFPYTAFDNNCYAFCCWVLDLNDSWLS
RRMIQRTTGFFRPYQDWNRKPLPTMDDSKIKKVANIFLCALSSLFTRPIKDIIGKIRP
LNILNILASCDWTFAGIVESLILLAELFGVFWTPPDVSAMIAPLLGDYELQGPEDLAV
ELVPVVMGGIGLVLGFTKEKIGKMLSSAASTLRACKDLGAYGLEILKLVMKWFFPKKE
EANELAIVRSIEDAVLDLEAIENNHMTTLLKDKDSLATYMRTLDLEEEKARKLSTKSA
SPDIVGTINALLARIAAARSLVHRAKEELSSRPRPVVLMISGRPGIGKTHLAREVAKR
IAASLTGDQRVGLIPRNGVDHWDAYKGERVVLWDDYGMSNPIHDALRLQELADTCPLT
LNCDRIENKGKVFDSDVIIITTNLANPAPLDYVNFEACSRRIDFLVYAEAPEVEKAKR
DFPGQPDMWKNAFSSDFSHIKLALAPQGGFDKNGNTPHGKGVMKTLTTGSLIARASGL
LHERLDEFELQGPALTTFNFDRNKVLAFRQLAAENKYGLMDTMRVGKQLKDVRTMPEL
KQALKNVSIKKCQIVYSGCTYMLESDGKGNVKVDRIQSAAVQTNNELAGALHHLRCAR
IRYYVKCVQEALYSIIQIAGAAFVTTRIAKRMNIQDLWSKPQVENTEETTSRDGCPKP
KDDEEFVISSDDIKTEGKKGKNKTGRGKKHTAFSSKGLSDEEYDEYKRIREERNGKYS
IEEYLQDRDKYYEEVAIARATEEDFCEEEEAKIRQRIFRPTRKQRKEERVSLGLVTGS
EIRKRNPDDFKPKGKLWADDDRSVDYNEKLSFEAPPSIWSRIVNFGSGWGFWVSPSLF
ITSTHVIPQGAKEFFGVPIKQIQVHKSGEFCRLRFPKPIRTDVTGMILEEGAPEGTVV
TLLIKRSTGELMPLAARMGTHATMKIQGRTVGGQMGMLLTGSNAKSMDLGTTPGDCGC
PYIYKRGNDYVVIGVHTAAARGGNTVICATQGSEGEATLEGGDNKGTYCGAPILGPGS
APTLSTKTKFWRSSTASLPPGTYEPAYLGGKDPRVKGGPSLQQVMREQLKPFTEPRGK
PPKPSVLEAAKKTIINVLEQTIDPPEKWSFAQACASLDKTTSSGHPHHMRKNDCWNGE
SFTGKLADQASKANLMFEEGKNVTPVYTAALKDELVKTDKIYGKIKKRLLWGSDLATM
IRCARAFGGLMDELKAHCVTLPIRVGMNMNEDGPIIFERHSRYTYHYDADYSRWDSTQ
QRAVLAAALEIMVKFSPEPHLAQVVAEDLLSPSVVDVGDFTISINEGLPSGVPCTSQW
NSIAHWLLTLCALSEVTNLSPDTIQANSLFSFYGDDEIVSTDIRLDPEKLTAKLREYG
LKPTRPDKTEGPLVISEDLNGLTFLRRTVTRDPAGWFGKLEQSSILRQIYWTRGPNHG
DPSETMIPHSQRPIQLMSLLGEAALHGPAFYSKISKLVIAELKEGGMDFYVPRQEPMF
RWMRFSDLSTWEGDRNLAPSFVNEDGVE"
mat_peptide <1..982
/gene="ORF1"
/product="p48"
mat_peptide 983..2080
/gene="ORF1"
/product="NTPase"
mat_peptide 2081..2617
/gene="ORF1"
/product="p22"
mat_peptide 2618..3016
/gene="ORF1"
/product="VPg"
mat_peptide 3017..3559
/gene="ORF1"
/product="Pro"
mat_peptide 3560..5089
/gene="ORF1"
/product="RdRp"
gene 5073..6695
/gene="ORF2"
CDS 5073..6695
/gene="ORF2"
/note="major capsid protein"
/codon_start=1
/product="VP1"
/protein_id="QBX91094.1"
/translation="MKMASSDANPSDGSAANLVPEVNNEVMALEPVVGAAIAAPVAGQ
QNVIDPWIRNNFVQAPGGEFTVSPRNAPGEILWSAPLGPDLNPYLSHLARMYNGYAGG
FEVQVILAGNAFTAGKVIFAAVPPNFPTEGLSPSQVTMFPHIVVDVRQLEPVLIPLPD
VRNNFYHYNQSNDPTIKLIAMLYTPLRANNAGDDVFTVSCRVLTRPSPDFDFIFLVPP
TVESRTKPFSVPVLTVEEMTNSRFPIPLEKLFTGPSSAFVVQPQNGRCTTDGVLLGTT
QLSPVNICTFRGDVTHITGSRNYTMNLASQNWNNYDPTEEIPAPLGAPDFVGKIQGML
TQTTRADGSTRGHKATVYTGSADFAPKLGRVQFETDTDHDFEANQNTKFTPVGVIQDG
STTHRNEPQQWVLPSYSGRNTHNVHLAPAVAPTFPGEQILFFRSTMPGCSGYPNMDLD
CLLPQEWVQYFYQEAAPAQSDVALLRFVNPDTGRVLFECKLHKSGYVTVAHTGQHDLV
IPPNGYFRFDSWVNQFYTLAPMGNGTGRRRVV"
gene 6695..7501
/gene="ORF3"
CDS 6695..7501
/gene="ORF3"
/note="minor structural protein; small basic protein"
/codon_start=1
/product="VP2"
/protein_id="QBX91095.1"
/translation="MAGAFFAGLASDVLGSGLGSLINAGAGAINQKVDFENNRKLQQA
SFQFSSNLQQASFQHDKEMLQAQIEATKKLQQEMMKVKQALLLEGGFSETDAARGAIN
APMTKALDWSGTRYWAPDARTTTYNAGRFSTPQPSGALPGRANLRDTVPARGSSSKSP
NPSTATSVYSNQTTSTRLGSTAGSGTSVSSLPSTARTRSWVEDQSRNLSPFMRGAHNI
SFVTPPSSKSSSQGTVSTVPKEVLDSWTGAFNTRRQPLFAHIRKRGESRA"
ORIGIN
1 ggcgtctagc gacgcttccg ctgccgctgt tgctaacagc aacaacgaca ccgcaaaatc
61 ttcaagtgac ggagtgcttt ctagcatggc tgtcactttt aaacgagccc tcggggcgcg
121 gcctaaacag ccacccccga gggaaaaacc acaaagaccc ccgcgaccac ctactccaga
181 actggttaag aatatccccc ctcccccacc caacggagag gatgaaatag tggtctctta
241 tagtgtcaaa gatggtgttt ccggcttgcc tgacctttct accgtcaggc aaccggaaga
301 gtctaacacg gccttcagtg tccctccact caatcagagg gagaatagag atgctaagga
361 gccactcact gggacaatcc tggaaatgtg ggacggggaa atctaccatt atggcctgta
421 tgtggagcga ggtcttgtac taggtgtgca caaaccgcca gctgccatca gccttgctaa
481 ggttgagctg gcaccactct ccttgtactg gagacctgtg tacactcctc agtacctcat
541 ctctccagac actctcaaga aattgtccgg agagacgttc ccctatacag cctttgataa
601 caactgttat gccttttgtt gctgggttct ggacctaaat gactcgtggc tgagtagaag
661 gatgatccag agaacgactg gtttcttcag gccctaccag gactggaata ggaaacccct
721 tcctactatg gatgactcca aaataaagaa ggtagctaac atatttctgt gtgccctgtc
781 ctcgctattc accagaccca taaaagacat aatagggaag ataaggcctc ttaatatcct
841 caacatcttg gcctcatgtg actggacctt cgcgggtata gtggagtctc tgatactctt
901 ggcagaactc tttggagtct tctggacacc cccagatgtg tctgcgatga ttgccccctt
961 acttggtgac tacgagctac aaggacctga ggaccttgca gtggagctcg tccccgtggt
1021 gatgggggga attggtttgg tgctaggatt caccaaagag aagattggga aaatgttgtc
1081 atctgctgcg tccactctga gagcttgcaa agaccttggt gcatatgggc tagagatcct
1141 aaagttagtc atgaagtggt tcttcccaaa gaaggaggag gcaaatgagc tggctatagt
1201 gaggtccatt gaggacgcag tcctggatct cgaggcaatt gaaaacaatc atatgaccac
1261 cttgcttaaa gataaagaca gcctggcaac ctacatgagg acacttgacc ttgaagagga
1321 gaaagccagg aaactctcaa ccaagtctgc ctcacctgac atcgtgggta caatcaacgc
1381 cctcctagcg agaattgctg ccgcacgttc tctggtgcat cgagcgaagg aggagctttc
1441 cagcagacca agacctgtgg tgttgatgat atcaggcaga ccaggaatag ggaagaccca
1501 cctcgctagg gaagtggcta agagaatcgc agcctccctt acaggggacc agcgtgtggg
1561 cctcattcca cgcaatggtg tcgaccattg ggatgcgtac aagggggaga gggtcgtcct
1621 gtgggacgat tatggaatga gcaaccctat tcacgatgcc ctcaggcttc aagaactcgc
1681 tgacacttgt cccctcactc tgaactgtga caggattgaa aataaaggaa aggtctttga
1741 cagcgatgtc atcattatca ccactaacct ggccaaccca gcaccactgg actatgtcaa
1801 ctttgaagca tgctcgaggc gcattgactt cctcgtgtat gcagaagccc ctgaagtcga
1861 aaaggcgaag cgtgacttcc caggccagcc tgacatgtgg aagaacgctt tcagttctga
1921 tttctcacac ataaaactag cactggcccc acaaggtggt ttcgataaga acggaaacac
1981 cccacacgga aagggcgtca tgaagaccct caccactggc tcccttattg cccgggcatc
2041 agggctactc catgagaggt tggatgaatt tgaactgcag ggtccggctc ttaccacctt
2101 caatttcgac cgcaataaag tgcttgcctt tagacagctt gctgctgaaa acaagtatgg
2161 attgatggac acaatgaggg ttgggaaaca gctcaaggat gtcagaacca tgccagaact
2221 caaacaagca ctcaagaatg tctcaatcaa gaagtgccaa atagtgtata gtggttgcac
2281 ttacatgctt gagtctgatg gcaagggcaa tgtgaaagtt gacagaatcc aaagtgccgc
2341 cgtgcagacc aacaatgagc tggctggtgc cctacaccac ttgaggtgcg ccagaatcag
2401 atactatgtc aagtgtgtcc aggaagccct gtattccatc atccaaatcg ctggggctgc
2461 atttgtcacc acgcgcattg ccaagcgcat gaacatacaa gacctatggt ccaagccaca
2521 agtggaaaac acagaggaga ctaccagcag ggacgggtgc ccaaaaccta aggatgatga
2581 ggagttcgtc atttcatccg acgacatcaa aactgagggc aagaaaggga agaacaagac
2641 tggccgtggc aagaagcaca cagcattttc aagcaaaggc ctcagtgatg aagagtatga
2701 tgaatacaag aggattagag aagaaaggaa tggcaagtac tctatagaag aatacctcca
2761 ggacagggac aaatactatg aggaggtggc cattgccagg gcgactgagg aagacttctg
2821 tgaagaggag gaggccaaga tccggcaaag gatctttaga ccaacaagga aacaacgcaa
2881 ggaggaaaga gtctctcttg gcctggtcac aggctctgaa attaggaaaa gaaacccaga
2941 tgacttcaaa cccaagggga agttgtgggc tgacgatgac aggagtgtgg actacaatga
3001 gaaactcagc tttgaggccc caccaagcat ttggtcgaga atagtcaact ttggttcagg
3061 ctggggattc tgggtctccc ccagtctgtt cataacatca acccatgtca taccccaagg
3121 cgcaaaggag ttctttggag tccccatcaa acaaatacag gtgcacaagt caggcgagtt
3181 ctgtcgcttg agattcccta aaccaatcag gactgatgtg acgggcatga tcttggaaga
3241 aggcgcacct gagggcaccg tggtcacact actcatcaaa aggtccactg gggaactcat
3301 gcccctagca gctaggatgg ggacccatgc gaccatgaag atccaagggc gcactgttgg
3361 aggccagatg ggcatgcttc tgacagggtc caatgccaag agcatggacc tgggtactac
3421 accaggtgat tgtggctgcc cctacatcta caagagaggt aatgactatg tggtcattgg
3481 agtccacacg gctgccgcac gtgggggaaa cactgtcata tgtgccaccc aagggagtga
3541 aggggaggct acgcttgagg gtggtgacaa caaagggaca tactgtggtg caccaatcct
3601 aggcccaggg agtgccccaa ctcttagcac caagaccaaa ttctggagat cgtccacagc
3661 atcacttcca cctggcacct atgaaccagc ctaccttggt ggcaaggacc ctagagtcaa
3721 gggtggccct tcactgcagc aagtcatgag ggaacagttg aagccgttca cagagcccag
3781 gggcaagcca ccaaaaccaa gtgtattaga agctgccaag aagaccatca ttaacgtcct
3841 tgagcaaaca attgatccac ctgagaaatg gtcgttcgca caagcttgcg cgtcccttga
3901 caagaccact tccagtggcc atccgcacca catgcggaaa aacgactgct ggaacgggga
3961 gtccttcaca ggcaagctgg cagaccaggc ttccaaggcc aacctgatgt ttgaagaagg
4021 gaagaacgtg accccagtct acacagctgc actcaaggat gagttagtta aaactgacaa
4081 aatttatggt aagatcaaga agaggcttct ctggggctcg gatttggcaa ccatgattcg
4141 gtgtgctcga gcattcggag gcctaatgga tgaactcaaa gcgcactgtg tcacactccc
4201 cattagagtt ggcatgaata tgaatgagga tggccccatc atcttcgaga ggcattccag
4261 gtacacgtac cactacgatg ctgactactc tcggtgggat tcaacacaac agagagccgt
4321 gttggcagca gctctagaaa tcatggttaa attctcccca gaaccacatt tggctcaggt
4381 agtcgcggaa gaccttcttt cccccagtgt ggtggacgtg ggcgacttca caatatcaat
4441 caatgagggt cttccctctg gggtgccctg cacctcccaa tggaactcca tcgcccactg
4501 gcttctcact ctctgtgcgc tctctgaagt cacaaacctg tctcctgata ccatacaggc
4561 taattccctc ttctcttttt atggtgatga tgaaattgtt agcacagaca taagattgga
4621 cccagagaaa ctgacagcaa aactcagaga atatgggtta aaaccaaccc gccctgacaa
4681 aactgaagga ccccttgtca tctctgaaga cctgaatggt ctaactttcc tgcggagaac
4741 tgtgacccgc gacccagctg gttggtttgg aaaactggag cagagttcaa tactcaggca
4801 aatctactgg actaggggtc ccaaccatgg agacccatct gaaacaatga ttccacactc
4861 ccaaagaccc atacaattga tgtccctact gggggaggcc gctctccacg gcccagcatt
4921 ttacagcaaa atcagcaaat tggtcattgc agagctaaaa gaaggtggta tggattttta
4981 cgtgcccaga caagagccaa tgttcagatg gatgagattc tcagatctga gcacgtggga
5041 gggcgatcgc aatctggctc ccagctttgt gaatgaagat ggcgtcgagt gacgccaacc
5101 catctgatgg gtccgcagcc aacctcgtcc cagaggtcaa caatgaggtc atggctctgg
5161 agcccgttgt tggtgccgcc attgcggcac ctgtagcggg ccaacaaaat gtaattgacc
5221 cctggattag aaacaatttt gtacaagccc ctggtggaga gtttacagtg tcccctagaa
5281 acgctccagg tgaaatacta tggagcgcgc ccttaggccc tgatctaaat ccctacctat
5341 cccatttggc cagaatgtat aatggttatg caggtggttt tgaagtgcag gtaattctcg
5401 cggggaacgc gttcaccgcc gggaaggtca tatttgcagc agtcccacca aattttccaa
5461 ctgaaggatt gagccccagc caggtcacta tgttccccca tatagtagta gatgttaggc
5521 aactagaacc tgtgttgatt cccctacccg atgttaggaa taatttctac cattacaacc
5581 aatcaaatga ccccaccatt aagttgatag caatgttgta tacaccactt agggccaata
5641 atgccgggga cgatgtcttc acagtttctt gccgagttct cacaagacca tcccccgatt
5701 ttgatttcat atttttagtg ccacccacag ttgagtcaag aactaaacca ttctctgtcc
5761 cagttctaac tgttgaggag atgaccaatt caagattccc catccctttg gaaaagttgt
5821 tcacgggtcc cagcagtgcc tttgttgttc aaccacaaaa cggcaggtgc acgactgatg
5881 gcgtgctcct aggcaccacc caactgtctc ctgtcaacat ctgcaccttc agaggggatg
5941 tcacccatat cacaggcagt cgtaattaca caatgaattt ggcttctcaa aattggaaca
6001 attatgaccc aacagaagaa atcccagccc ctctaggagc tccagacttt gtggggaaga
6061 tccaaggcat gctcacccaa accacgaggg ctgatggttc aacacgcggc cacaaagcca
6121 cagtgtacac tgggagcgcc gactttgctc caaaactggg tagagtccaa tttgaaactg
6181 acacagacca tgattttgaa gctaaccaaa atacaaagtt caccccagtc ggtgtcatcc
6241 aagatggtag caccacccac cgaaatgaac cccaacagtg ggtgctccca agttactcag
6301 gcagaaatac tcataatgtg catttggccc ccgctgtagc ccccactttt ccgggtgagc
6361 aaattctctt cttcagatcc accatgcccg gatgcagcgg gtatcccaac atggatttgg
6421 actgtctgct cccccaggaa tgggtgcagt acttctacca agaggcagcc ccagcacaat
6481 ctgatgtggc tctgctaaga tttgtgaatc cagatacagg tagggttttg tttgagtgta
6541 agcttcataa atcaggctat gttacagtgg ctcacactgg ccaacatgat ttggttatcc
6601 cccccaatgg ttattttagg tttgattctt gggtcaacca gttctacacg cttgccccca
6661 tgggaaatgg aacggggcgt agacgtgtag tataatggct ggagctttct ttgctggatt
6721 ggcatctgat gtccttggct ctggacttgg ttccctcatc aatgctgggg ctggggccat
6781 caaccaaaaa gttgattttg aaaataacag aaaattacaa caggcatcct tccaatttag
6841 cagcaatctg caacaggctt cctttcaaca tgacaaagag atgctccaag cacaaattga
6901 ggccaccaaa aagctacaac aggaaatgat gaaagttaag caggcattgc tcctagaggg
6961 tgggttctct gagacagatg cagcccgcgg ggcaattaac gctcccatga caaaagcttt
7021 ggactggagc gggacaaggt actgggctcc cgatgctagg actacaacat ataatgcagg
7081 ccgcttttcc acccctcaac catcgggggc actgccagga agagctaatc ttagggatac
7141 tgtccctgct cggggttcct ctagtaaatc ccctaaccct tctactgcca cttctgtgta
7201 ctcaaatcaa accacttcaa cgagacttgg ttctacagct ggttctggta ccagtgtctc
7261 gagcctcccg tcaactgcaa ggactaggag ctgggttgag gatcaaagta ggaatttgtc
7321 acctttcatg aggggggccc acaacatatc gtttgtcacc ccaccatcta gcaaatcctc
7381 tagccaaggc acagtctcaa ccgtgcctaa agaggttttg gactcctgga ctggcgcttt
7441 caacacgcgc agacagcctc tcttcgctca cattcgtaag cgaggggagt cacgggcgta
7501 atgtgaaaag acaaaattga ttatctttct ctctttttct ttcttta
//