Typing tool
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Typing tool
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Complete norovirus genomes
| MK762560 | GII.13 | |
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| GII.P16 |
ORF1: 1..5097
ORF2: 5078..6706
ORF3: 6706..7437
LOCUS MK762560 7450 bp RNA linear VRL 13-APR-2019
DEFINITION Norovirus GII isolate Hu/PR/2014/GII.P16-GII.13/Bayamon0178
nonstructural polyprotein (ORF1), VP1 (ORF2), and VP2 (ORF3) genes,
complete cds.
ACCESSION MK762560
VERSION MK762560.1
KEYWORDS .
SOURCE Norovirus GII
ORGANISM Norovirus GII
Viruses; Riboviria; Orthornavirae; Pisuviricota; Pisoniviricetes;
Picornavirales; Caliciviridae; Norovirus; Norwalk virus.
REFERENCE 1 (bases 1 to 7450)
AUTHORS Barclay,L., Cannon,J.L., Wikswo,M.E., Phillips,A., Browne,H.,
Montmayeur,A.M., Tatusov,R.L., Burke,R.M., Hall,A.J. and Vinje,J.
TITLE Emergence and characterization of multiple viruses associated with
a novel GII.P16 polymerase in the United States, 2015-2018
JOURNAL Unpublished
REFERENCE 2 (bases 1 to 7450)
AUTHORS Barclay,L., Cannon,J.L., Montmayeur,A.M., Tatusov,R.L., Chhabra,P.
and Vinje,J.
TITLE Direct Submission
JOURNAL Submitted (05-APR-2019) Division of Viral Diseases, Centers for
Disease Control and Prevention, 1600 Clifton Road NE, Atlanta, GA
30329, USA
COMMENT ##Assembly-Data-START##
Assembly Method :: Geneious v. R10; SPAdes v. 3.6
Sequencing Technology :: Illumina
##Assembly-Data-END##
FEATURES Location/Qualifiers
source 1..7450
/organism="Norovirus GII"
/mol_type="genomic RNA"
/strain="Bayamon0178"
/isolate="Hu/PR/2014/GII.P16-GII.13/Bayamon0178"
/isolation_source="stool"
/host="Homo sapiens"
/db_xref="taxon:122929"
/country="Puerto Rico"
/collection_date="24-Mar-2014"
/note="genotype: GII.P16-GII.13"
gene 1..5097
/gene="ORF1"
CDS 1..5097
/gene="ORF1"
/codon_start=1
/product="nonstructural polyprotein"
/protein_id="QBX91007.1"
/translation="MKMASNDATVAVACNNNNDKEKSSGEGLFTNMSSTLKKALGARP
KQPAPRDNSQKPPRPPTPELVKRIPPPPPNGEEEEPVIRYEVKSGISGLPELTTVPQP
DVANTAFSVPPLSLRENREAKEPLTGAILEMWDGEIYHYGLYVEKGLVLGVHKPPAAI
SMAKVELTPLSLYWRVVYTPQYLISPETLRRLNGEAFPYTAFDNNCYAFCCWVLDLND
SWLNRRMVQRTTGFFRPYQEWNRKPLPTMDDSKIKKVANIFLCSLSTLFTRPIKDLIG
KIKPLNILNILATCDWTFAGIVESLILLAELFGVFWTPPDVSAMIAPLLGDYELQGPE
DLAVELVPVVMGGIGLVLGFTKEKIGKMLSSAASTLRACKDLGAYGLEILKLVMKWFF
PKKEEANELAMVRAIEDAVLDLEAIENNHMTTLLKDKDSLATYMKTLDMEEEKARRLS
TKSASPDIVGTINALLARIAAARSLVHRAKEELSSRIRPVVVMISGKPGIGKTHLARE
VARKVASTLTGDQRVGLIPRNGVDHWDAYKGERVVLWDDYGMSNPIHDALRIQELADT
CPLTLNCDRIENKGKVFDSEVIIITTNLANPAPLDYVNFEACSRRIDFLVYAEAPEVE
KAKRDFPGQPDMWKDAFKSDFSHIKLQLAPQGGFDKNGNTPHGKGVMKTLTTGSLIAR
ASGLLHERMDEFELQGPTVTTFNFDRNRIAAFRQLAAENKYGLVDTMRVGNQLKGVKT
MEELKQAIKNVIIKRCRIIYGGSTYDLESDGKGRVLVEKVKNTSVQTNNELAGALHHL
KHARIRYYVKCVQEAVYSIIQIAGAAFVTTRIVRRMNIQELWSKPPLDQNESEAKEEA
PKSEDDEFIISSKDIKEEGKKGKNKTGRGKKHTAFSSKGLSDEEYDEYKRIREERNGK
YSIEEYLQDRDRYYEELAIAKATEEDFCEEEEIKIRQRIFRPTRKQRKEERVTLGLVT
GSEIRKRNPDDFKPKGKLWADDNRSVDYNEKLDFEAPPSIWSRIVSFGSGWGFWVSPS
LFITSTHVIPAGITEAFGVPIKQIQVHKSGEFCRFRFPKPIRSDVTGMILEEGAPEGT
VATVLIKRPTGELMPLAARMGTHATMKIQGRMVGGQMGMLLTGSNAKGMDLGTTPGDC
GCPYIYKRGNDYIVIGVHTAAARGGNTVICATQGSEGEATLEGGDDKGTYCGAPILGP
GGAPKLSTKTKFWRSSNTPLPPGTYEPAYLGGRDPRVKGGPSLQQVMRDQLKPFTEPR
GKPPRPSVLEAAKQTIINVLEQTLDPPQKWTYAQACASLDKTTSSGHPHHVRKNEFWN
GETFTGKLADQASKANLMFEEGKHMTPVYTAALKDELVKTDKVYGKIKKRLLWGSDLS
TMIRCARSFGGLMDEMKAHCISLPVRVGMNMNEDGPIIFEKHSRYKYHYDADYSRWDS
TQQRVVLAAALEIMVRFSAEPQLAQIVAEDLLAPSVVDVGDFKISINEGLPSGVPCTS
QWNSIAHWLLTLCALSEVTKLSPDIVQANSMFSFYGDDEIVSTDIKLDPEKLTTKLKE
YGLKPTRPDKTEGPLIISEDLNGLTFLRRTVTRDPAGWFGKLDQSSILRQMYWTRGPN
HEDPNETMIPHSQRPIQLMALLGEASLHGPSFYSKISKLVITELKEGGMDFYVPRQEP
MFRWMRFSDLSTWEGDRNLAPNFVNEDGVE"
mat_peptide 1..993
/gene="ORF1"
/product="p48"
mat_peptide 994..2091
/gene="ORF1"
/product="NTPase"
mat_peptide 2092..2622
/gene="ORF1"
/product="p22"
mat_peptide 2623..3021
/gene="ORF1"
/product="VPg"
mat_peptide 3022..3564
/gene="ORF1"
/product="Pro"
mat_peptide 3565..5094
/gene="ORF1"
/product="RdRp"
gene 5078..6706
/gene="ORF2"
CDS 5078..6706
/gene="ORF2"
/note="major capsid protein"
/codon_start=1
/product="VP1"
/protein_id="QBX91008.1"
/translation="MKMASNDAAPSNDGAASLVPEAINETMPLEPVAGASIAAPVAGQ
TNIIDPWIRTNFVQAPNGEFTVSPRNSPGEILLNLELGPDLNPYLAHLSRMYNGYAGG
VEVQVLLAGNAFTAGKILFAAIPPNFPVDMISPAQITMLPHLIVDVRTLEPIMIPLPD
VRNVFYHFNNQPQPRMRLVAMLYTPLRSNGSGDDVFTVSCRVLTRPTPDFEFIYLVPP
SVESKTKPFTLPILTISELTNSRFPIPIEQLYTAPNENNVVQCQNGRCTLDGELQGTT
QLLSSAVCSYRGRTVANSGDNWDQNLLQLTYPSGASYDPTDEVPAPLGTQDFSGILYG
VLTQDNVSEGTGEAKNAKGVYISTTSGRFTPKIGTIGLHSITENVHPNQQSRFTPVGV
AQNENTPFQQWVLPHYAGALALNTNLAPAVAPTFPGEQLLFFRSRVPCVQGLRGQDAF
IDCLLPQEWVNHFYQEAAPSQADVALIRYVNPDTGRTLFEAKLHRSGFITVSHTGTYP
LVVPPNGHFRFDSWVNQFYSLAPMGTGNGRRRVQ"
gene 6706..7437
/gene="ORF3"
CDS 6706..7437
/gene="ORF3"
/note="minor structural protein; small basic protein"
/codon_start=1
/product="VP2"
/protein_id="QBX91009.1"
/translation="MAGAFIAGLAGDMLTSAVGSLTSAGANAINQKLNFDYNKQLQNA
SFQHDKEMLQAQIDATKKLQSEMIAIKHGVLTAGGFSPADAARGAVNAPMTRVLDWSG
TRYYAPNSVQTTSYSGQFTPSPVHRAQVKSPSNSSQRTAAPSSIRSLSTQSTSLGSTS
SEGSSTTSSSSRTADWVQQQRALSPYMQGALQTAYVTPPSSRASSMSSVSTVPKGVLD
SWTPVFNTRRQPLFAHLRKRGESQA"
ORIGIN
1 atgaagatgg cgtctaacga cgctaccgtt gccgttgctt gcaacaacaa caacgacaag
61 gaaaaatctt caggtgaagg cttattcaca aacatgtctt ccaccttaaa gaaagccctc
121 ggggcccggc ccaaacagcc tgccccgagg gacaactcac aaaagccccc aagaccacca
181 actcccgagt tggttaagag gataccccct cccccaccta atggagaaga agaagaacca
241 gtcattaggt atgaggttaa gagtggaatc tctggcctgc ccgagctcac aacagtccct
301 caaccggatg tggccaacac ggcattcagt gtcccaccgc tgagcttgag agaaaacagg
361 gaggccaagg aaccgctgac aggggcaata ttagagatgt gggatggaga gatataccac
421 tatggtctgt acgtggagaa aggcttagtg ttgggtgtgc acaaaccacc tgcagctata
481 agcatggcaa aagtggagct gacgccgttg tcattgtact ggcgtgtggt ctacaccccc
541 caatacctca tctcccctga aactctcagg aggctcaacg gagaggcatt cccttacact
601 gcctttgaca acaactgcta tgccttttgc tgttgggtat tagacctcaa tgactcatgg
661 cttaacagga ggatggtgca aagaacaaca ggcttcttca gaccttacca agagtggaac
721 agaaaacccc tgcccactat ggatgactcc aaaatcaaga aggtggcaaa catattcctg
781 tgttcattgt ccacgttgtt caccagacct ataaaagacc tcataggaaa aattaagcca
841 ttaaacatct tgaacatcct ggcaacgtgt gactggacat tcgccggaat agtggagtct
901 ctgatattac ttgctgaact ctttggagtt ttctggacac ccccagatgt gtctgctatg
961 atcgctcctt tacttggaga ctacgagttg caagggccag aagaccttgc cgttgagctc
1021 gtacctgtag taatgggagg gattggtttg gtgttgggat tcaccaaaga gaaaattgga
1081 aaaatgttgt cctcagcagc atcaacgctc agggcttgta aagatcttgg tgcctatggc
1141 ttagagatac tcaaattggt catgaagtgg ttcttcccaa agaaagaaga ggccaatgag
1201 ctagccatgg tgagagctat agaggatgct gtactggatc ttgaggcaat agaaaataat
1261 cacatgacaa ctctgttgaa agacaaagac agcctagcaa cctacatgaa aacactagac
1321 atggaggagg aaaaagccag aagattgtcc acaaaatctg catcccctga catagttggg
1381 acgatcaacg ccctgctggc tcgaatagca gcggctaggt cactagtcca cagggccaag
1441 gaggagttat ctagcaggat aagaccagtg gttgttatga tatctggcaa accagggata
1501 ggcaaaactc atttggccag ggaggtggca agaaaggtgg catccactct cacaggggat
1561 caaagagtcg ggctcatacc gagaaacggt gtggaccatt gggatgcata caaaggtgag
1621 agagtcgtgc tgtgggacga ctatggcatg agcaacccca ttcatgatgc tctgcgcata
1681 caagaattgg ctgatacgtg tccccttacc ttaaattgtg acagaattga aaataaggga
1741 aaagtttttg acagtgaagt cataataatc acaacaaacc ttgccaatcc agctccactt
1801 gattatgtca actttgaggc ctgttccagg agaattgact tcctggtgta cgccgaggca
1861 ccagaagtag aaaaggcgaa acgagacttt cctggtcaac cagatatgtg gaaggacgcc
1921 ttcaagtcgg acttttcaca tatcaagttg caacttgcac ctcagggcgg ctttgacaag
1981 aatggcaaca ccccacatgg gaaaggagtg atgaagaccc tcaccaccgg ttccctgatc
2041 gcccgtgcat caggcttact gcatgagagg atggatgaat ttgaactcca aggccccaca
2101 gtcaccacct tcaattttga ccggaacaga atcgctgcat tcagacaatt ggctgcagaa
2161 aacaagtatg gattggtgga caccatgaga gttggcaatc aattaaaagg ggtgaaaacc
2221 atggaagaac tcaaacaagc aatcaagaat gtgatcatca agaggtgccg gatcatctac
2281 ggcggctcca cgtatgacct tgaatctgat ggcaagggca gagttctggt ggaaaaggtc
2341 aagaacacct ctgtacagac caacaacgag ttggccggag ccctgcatca cctcaaacat
2401 gcccgaatca ggtactatgt caaatgtgtg caagaagcag tctactctat tatacaaatc
2461 gccggcgctg cgtttgtcac cacacgcata gtacgccgca tgaacataca agagctttgg
2521 tcgaagccac cattagacca aaatgaatca gaggctaagg aagaggcccc caagtcagaa
2581 gatgacgagt tcatcatatc ttctaaggac atcaaggagg aaggaaagaa gggcaaaaac
2641 aaaactggcc gtggcaagaa acatactgca ttctctagca agggcttgag cgatgaggag
2701 tatgacgagt acaagaggat aagagaagag agaaatggga agtactctat agaggagtat
2761 cttcaagaca gagacaggta ctatgaggaa ctcgccatcg ccaaggccac ggaagaagac
2821 ttctgtgagg aggaggagat caaaatccgt cagaggatct tccgtcccac caggaagcaa
2881 aggaaggaag agagggtcac actagggcta gtaactggtt cagaaatcag aaaaagaaac
2941 cctgatgact tcaaacctaa agggaaactg tgggctgatg acaacagaag tgttgattac
3001 aatgagaaac tggactttga ggccccccca agcatatggt ctaggattgt gagttttggt
3061 tctggttggg gcttctgggt gtcaccaagc ctgttcataa catcaactca cgtaatccct
3121 gcaggcataa cagaggcatt tggagtcccc atcaaacaaa tccaggtcca caaatcaggt
3181 gaattttgtc ggttcagatt cccaaaacca attagatcag atgtgacagg aatgatcttg
3241 gaagaaggtg cgcctgaggg caccgtggca accgtgctca tcaaacgccc taccggagag
3301 ctcatgcccc ttgcagccag aatgggaaca cacgcaacca tgaaaattca gggccgcatg
3361 gttggcgggc agatgggtat gttgctcact ggttcaaatg ctaaaggaat ggatttggga
3421 acaactcctg gtgattgtgg ctgtccctac atctacaaaa ggggcaatga ctatatagtc
3481 attggggtgc acacagcagc agcccgtggt ggaaacaccg tcatctgtgc cacacaggga
3541 agtgagggtg aggcaactct tgagggtgga gatgacaaag gaacatactg tggggcaccc
3601 attctaggcc ctgggggggc accaaaattg agcaccaaaa ccaaattttg gaggtcatcg
3661 aacacgcctc ttccaccagg gacgtatgag cctgcctacc tcggtggccg tgacccgcgt
3721 gttaagggtg ggccctcctt gcagcaggta atgagagatc agttgaagcc attcaccgag
3781 cccaggggta aacctccaag accaagtgtg ttggaagcag ctaaacaaac catcatcaat
3841 gtcctcgaac aaaccctgga ccctccacaa aaatggacat acgcacaggc gtgtgcttca
3901 cttgacaaaa ccacctccag cgggcatccc caccacgtcc gaaagaatga attctggaat
3961 ggtgagacct tcactggtaa attggcagac caagcatcaa aagcaaatct aatgtttgag
4021 gaagggaaac acatgacacc agtgtataca gcagccctca aggatgagct ggtcaagact
4081 gacaaagtct atggaaagat caagaagaga ctgctctggg gctctgactt gtccaccatg
4141 atccggtgcg ccaggtcctt tggtgggctc atggatgaga tgaaagcaca ctgcatatca
4201 ctcccagtcc gagttggcat gaacatgaat gaagatggtc caataatatt tgagaagcac
4261 tccagatata agtatcacta tgatgcagat tactcccgct gggattcaac acaacagagg
4321 gtagtactag cagcagcctt ggagatcatg gtcaggttct ctgcagagcc acaattggca
4381 caaatagtcg ctgaggatct gctggccccc agtgtggtag atgtaggaga ctttaaaatt
4441 tcaataaatg aagggctccc ctctggtgta ccatgcactt ctcaatggaa ttccatcgca
4501 cactggctgc taaccctctg cgccttgtct gaagtcacca aactgtcccc tgacattgta
4561 caggcaaatt ccatgttctc attttacggt gatgacgaga ttgtcagcac cgatataaaa
4621 ttggaccctg aaaagttaac caccaaattg aaggagtacg gcctgaaacc aactcgccca
4681 gacaaaaccg agggacccct gatcatcagt gaggatttga acggactcac tttcctccgg
4741 aggacggtga ctcgtgaccc agctggctgg tttggaaaat tggaccaaag ctcaatattg
4801 aggcagatgt actggactag aggaccaaat catgaagacc ccaatgagac aatgataccc
4861 cactctcaaa gacccataca gctcatggca ctgcttggtg aggcctccct tcacggaccc
4921 tctttctaca gcaaaattag taagttggtc ataactgaac tcaaagaagg tgggatggac
4981 ttttacgtgc caaggcagga acccatgttc aggtggatga ggttttctga cttgagcacg
5041 tgggagggcg atcgcaatct ggctcccaat tttgtgaatg aagatggcgt cgaatgacgc
5101 cgctccatcg aatgatggtg cagctagtct cgtaccagag gccattaatg agactatgcc
5161 attggaaccc gttgctggcg catctattgc tgccccagtg gcgggacaaa ctaacataat
5221 tgacccctgg ataagaacaa attttgtgca agcccctaat ggagagttta cagtatcacc
5281 gagaaattcc cctggagaga ttctattaaa tttagagttg ggaccagatt tgaatcctta
5341 tttggcccat ctatcaagga tgtacaatgg atacgctgga ggtgttgagg tgcaagtgct
5401 tcttgctggg aacgcgttca cagcaggaaa gatattattt gcagcaatcc cacccaactt
5461 tcctgtagat atgatcagcc cagctcaaat tactatgctt ccccatttga ttgtagatgt
5521 taggacattg gaacctatta tgataccctt acctgatgtt aggaatgtgt tctatcattt
5581 taataatcaa ccccaaccta ggatgagatt agtggctatg ctctataccc cattgagatc
5641 taatggttca ggagatgatg tctttactgt gtcttgtaga gtgttgacta ggccaacccc
5701 tgactttgaa ttcatttacc tagtgcctcc ctctgtagag tccaaaacta aaccattcac
5761 acttccaata ttgaccattt ctgaactaac caactcccgg tttcccatcc caattgagca
5821 actgtacacg gccccaaatg agaataatgt tgtgcagtgt caaaatggaa ggtgcacctt
5881 ggatggagag cttcagggca ccacccagct gctatcaagt gcagtttgct cgtacagggg
5941 caggactgtg gctaacagtg gggacaattg ggaccagaat ttgctccagc tgacctaccc
6001 aagcggtgca agctatgacc ccactgatga agtaccagca cccttgggca cccaggattt
6061 cagtgggata ttgtatgggg tgttaaccca agacaatgta agtgagggta caggggaggc
6121 caaaaatgct aagggagtat acatatccac caccagtgga agattcaccc caaaaattgg
6181 gacaattgga ttgcattcaa taactgaaaa tgtgcacccc aatcagcaat cacggttcac
6241 ccccgttgga gtcgctcaga atgaaaacac ccccttccag caatgggttc taccacacta
6301 cgcaggtgct ctcgctctaa ataccaattt ggcacccgct gttgccccga ctttccctgg
6361 cgagcaatta ctgttcttca ggtcccgtgt tccatgtgtt caaggtctgc gggggcagga
6421 tgctttcata gattgtctcc tacctcaaga gtgggtgaac catttttatc aagaggctgc
6481 tccctcccaa gcagacgttg ccctcatcag gtatgtcaac cctgatactg gtcgcacgtt
6541 gtttgaggcc aaattgcaca ggtcaggttt cattactgta tcacacactg gtacctaccc
6601 tcttgtggtc cccccaaatg gtcatttcag gtttgactct tgggttaacc aattctactc
6661 actcgccccc atgggaactg gcaatgggcg tagaagagtt caataatggc aggagcattc
6721 atagctggtc tagccggtga catgctgact tctgctgttg gttcactgac ctctgcagga
6781 gccaatgcca tcaatcagaa attgaatttt gattacaata aacaactcca aaatgcatcc
6841 tttcaacatg ataaggaaat gttgcaggcc caaattgatg ctacaaagaa gctccaatca
6901 gaaatgattg caattaagca tggggttctg accgcgggcg gcttttcccc agctgatgca
6961 gccagagggg cagtcaacgc cccaatgact cgagtgttgg attggtcagg gacacgctac
7021 tacgctccaa attctgtgca aaccaccagt tattctgggc aattcacccc ctcgcctgtc
7081 catcgggcgc aggtgaagtc cccttccaat tcatctcagc ggactgcagc tccaagcagt
7141 atccgcagcc tgtcaaccca atcaacttct ttaggctcca cctcctcaga ggggtcctct
7201 acaacctcct ctagttcgag gacagcagac tgggtgcaac aacaaagggc tcttagcccg
7261 tacatgcagg gagccctgca gacggcatac gtcacaccgc cgtctagtag ggcttccagt
7321 atgagctctg tctcaacagt gcccaaaggg gttttggact cctggacgcc tgtgtttaac
7381 acacgcaggc agccgctgtt tgcacacctc aggaagaggg gggagtcaca ggcttagtga
7441 aaaggataat
//