Typing tool
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Typing tool
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Complete norovirus genomes
| MK762559 | GII.13 | |
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| GII.P16 |
ORF1: 1..5043
ORF2: 5024..6652
ORF3: 6652..7383
LOCUS MK762559 7390 bp RNA linear VRL 13-APR-2019
DEFINITION Norovirus GII isolate Hu/PR/2014/GII.P16-GII.13/Bayamon0177
nonstructural polyprotein (ORF1) gene, partial cds; and VP1 (ORF2)
and VP2 (ORF3) genes, complete cds.
ACCESSION MK762559
VERSION MK762559.1
KEYWORDS .
SOURCE Norovirus GII
ORGANISM Norovirus GII
Viruses; Riboviria; Orthornavirae; Pisuviricota; Pisoniviricetes;
Picornavirales; Caliciviridae; Norovirus; Norwalk virus.
REFERENCE 1 (bases 1 to 7390)
AUTHORS Barclay,L., Cannon,J.L., Wikswo,M.E., Phillips,A., Browne,H.,
Montmayeur,A.M., Tatusov,R.L., Burke,R.M., Hall,A.J. and Vinje,J.
TITLE Emergence and characterization of multiple viruses associated with
a novel GII.P16 polymerase in the United States, 2015-2018
JOURNAL Unpublished
REFERENCE 2 (bases 1 to 7390)
AUTHORS Barclay,L., Cannon,J.L., Montmayeur,A.M., Tatusov,R.L., Chhabra,P.
and Vinje,J.
TITLE Direct Submission
JOURNAL Submitted (05-APR-2019) Division of Viral Diseases, Centers for
Disease Control and Prevention, 1600 Clifton Road NE, Atlanta, GA
30329, USA
COMMENT ##Assembly-Data-START##
Assembly Method :: Geneious v. R10; SPAdes v. 3.6
Sequencing Technology :: Illumina
##Assembly-Data-END##
FEATURES Location/Qualifiers
source 1..7390
/organism="Norovirus GII"
/mol_type="genomic RNA"
/strain="Bayamon0177"
/isolate="Hu/PR/2014/GII.P16-GII.13/Bayamon0177"
/isolation_source="stool"
/host="Homo sapiens"
/db_xref="taxon:122929"
/country="Puerto Rico"
/collection_date="24-Mar-2014"
/note="genotype: GII.P16-GII.13"
gene <1..5043
/gene="ORF1"
CDS <1..5043
/gene="ORF1"
/codon_start=1
/product="nonstructural polyprotein"
/protein_id="QBX91004.1"
/translation="DKEKSSGEGLFTNMSSTLKKALGARPKQPAPRDNSQKPPRPPTP
ELVKRIPPPPPNGEEEEPVIRYEVKSGISGLPELTTVPQPDVANTAFSVPPLSLRENR
EAKEPLTGAILEMWDGEIYHYGLYVEKGLVLGVHKPPAAISMAKVELTPLSLYWRVVY
TPQYLISPETLRRLNGEAFPYTAFDNNCYAFCCWVLDLNDSWLNRRMVQRTTGFFRPY
QEWNRKPLPTMDDSKIKKVANIFLCSLSTLFTRPIKDLIGKIKPLNILNILATCDWTF
AGIVESLILLAELFGVFWTPPDVSAMIAPLLGDYELQGPEDLAVELVPVVMGGIGLVL
GFTKEKIGKMLSSAASTLRACKDLGAYGLEILKLVMKWFFPKKEEANELAMVRAIEDA
VLDLEAIENNHMTTLLKDKDSLATYMKTLDMEEEKARRLSTKSASPDIVGTINALLAR
IAAARSLVHRAKEELSSRIRPVVVMISGKPGIGKTHLAREVARKVASTLTGDQRVGLI
PRNGVDHWDAYKGERVVLWDDYGMSNPIHDALRIQELADTCPLTLNCDRIENKGKVFD
SEVIIITTNLANPAPLDYVNFEACSRRIDFLVYAEAPEVEKAKRDFPGQPDMWKDAFK
SDFSHIKLQLAPQGGFDKNGNTPHGKGVMKTLTTGSLIARASGLLHERMDEFELQGPT
VTTFNFDRNRIAAFRQLAAENKYGLVDTMRVGNQLKGVKTMEELKQAIKNVIIKRCRI
IYGGSTYDLESDGKGRVLVEKVKNTSVQTNNELAGALHHLKHARIRYYVKCVQEAVYS
IIQIAGAAFVTTRIVRRMNIQELWSKPPLDQNESEAKEEAPKSEDDEFIISSKDIKEE
GKKGKNKTGRGKKHTAFSSKGLSDEEYDEYKRIREERNGKYSIEEYLQDRDRYYEELA
IAKATEEDFCEEEEIKIRQRIFRPTRKQRKEERVTLGLVTGSEIRKRNPDDFKPKGKL
WADDNRSVDYNEKLDFEAPPSIWSRIVSFGSGWGFWVSPSLFITSTHVIPAGITEAFG
VPIKQIQVHKSGEFCRFRFPKPIRSDVTGMILEEGAPEGTVATVLIKRPTGELMPLAA
RMGTHATMKIQGRMVGGQMGMLLTGSNAKGMDLGTTPGDCGCPYIYKRGNDYIVIGVH
TAAARGGNTVICATQGSEGEATLEGGDDKGTYCGAPILGPGGAPKLSTKTKFWRSSNT
PLPPGTYEPAYLGGRDPRVKGGPSLQQVMRDQLKPFTEPRGKPPRPSVLEAAKQTIIN
VLEQTLDPPQKWTYAQACASLDKTTSSGHPHHVRKNEFWNGETFTGKLADQASKANLM
FEEGKHMTPVYTAALKDELVKTDKVYGKIKKRLLWGSDLSTMIRCARSFGGLMDEMKA
HCISLPVRVGMNMNEDGPIIFEKHSRYKYHYDADYSRWDSTQQRVVLAAALEIMVRFS
AEPQLAQIVAEDLLAPSVVDVGDFKISINEGLPSGVPCTSQWNSIAHWLLTLCALSEV
TKLSPDIVQANSMFSFYGDDEIVSTDIKLDPEKLTTKLKEYGLKPTRPDKTEGPLIIS
EDLNGLTFLRRTVTRDPAGWFGKLDQSSILRQMYWTRGPNHEDPNETMIPHSQRPIQL
MALLGEASLHGPSFYSKISKLVITELKEGGMDFYVPRQEPMFRWMRFSDLSTWEGDRN
LAPNFVNEDGVE"
mat_peptide <1..939
/gene="ORF1"
/product="p48"
mat_peptide 940..2037
/gene="ORF1"
/product="NTPase"
mat_peptide 2038..2568
/gene="ORF1"
/product="p22"
mat_peptide 2569..2967
/gene="ORF1"
/product="VPg"
mat_peptide 2968..3510
/gene="ORF1"
/product="Pro"
mat_peptide 3511..5040
/gene="ORF1"
/product="RdRp"
gene 5024..6652
/gene="ORF2"
CDS 5024..6652
/gene="ORF2"
/note="major capsid protein"
/codon_start=1
/product="VP1"
/protein_id="QBX91005.1"
/translation="MKMASNDAAPSNDGAASLVPEAINETMPLEPVAGASIAAPVAGQ
TNIIDPWIRTNFVQAPNGEFTVSPRNSPGEILLNLELGPDLNPYLAHLSRMYNGYAGG
VEVQVLLAGNAFTAGKILFAAIPPNFPVDMISPAQITMLPHLIVDVRTLEPIMIPLPD
VRNVFYHFNNQPQPRMRLVAMLYTPLRSNGSGDDVFTVSCRVLTRPTPDFEFIYLVPP
SVESKTKPFTLPILTISELTNSRFPIPIEQLYTAPNENNVVQCQNGRCTLDGELQGTT
QLLSSAVCSYRGRTVANSGDNWDQNLLQLTYPSGASYDPTDEVPAPLGTQDFSGILYG
VLTQDNVSEGTGEAKNAKGVYISTTSGRFTPKIGTIGLHSITENVHPNQQSRFTPVGV
AQNENTPFQQWVLPHYAGALALNTNLAPAVAPTFPGEQLLFFRSRVPCVQGLRGQDAF
IDCLLPQEWVNHFYQEAAPSQADVALIRYVNPDTGRTLFEAKLHRSGFITVSHTGTYP
LVVPPNGHFRFDSWVNQFYSLAPMGTGNGRRRVQ"
gene 6652..7383
/gene="ORF3"
CDS 6652..7383
/gene="ORF3"
/note="minor structural protein; small basic protein"
/codon_start=1
/product="VP2"
/protein_id="QBX91006.1"
/translation="MAGAFIAGLAGDMLTSAVGSLTSAGANAINQKLNFDYNKQLQNA
SFQHDKEMLQAQIDATKKLQSEMIAIKHGVLTAGGFSPADAARGAVNAPMTRVLDWSG
TRYYAPNSVQTTSYSGQFTPSPVHRAQVKSPSNSSQRTAAPSSIRSLSTQSTSLGSTS
SEGSSTTSSSSRTADWVQQQRALSPYMQGALQTAYVTPPSSRASSMSSVSTVPKGVLD
SWTPVFNTRRQPLFAHLRKRGESQA"
ORIGIN
1 gacaaggaaa aatcttcagg tgaaggctta ttcacaaaca tgtcttccac cttaaagaaa
61 gccctcgggg cccggcccaa acagcctgcc ccgagggaca actcacaaaa gcccccaaga
121 ccaccaactc ccgagttggt taagaggata ccccctcccc cacctaatgg agaagaagaa
181 gaaccagtca ttaggtatga ggttaagagt ggaatctctg gcctgcccga gctcacaaca
241 gtccctcaac cggatgtggc caacacggca ttcagtgtcc caccgctgag cttgagagaa
301 aacagggagg ccaaggaacc gctgacaggg gcaatattag agatgtggga tggagagata
361 taccactatg gtctgtacgt ggagaaaggc ttagtgttgg gtgtgcacaa accacctgca
421 gctataagca tggcaaaagt ggagctgacg ccgttgtcat tgtactggcg tgtggtctac
481 accccccaat acctcatctc ccctgaaact ctcaggaggc tcaacggaga ggcattccct
541 tacactgcct ttgacaacaa ctgctatgcc ttttgctgtt gggtattaga cctcaatgac
601 tcatggctta acaggaggat ggtgcaaaga acaacaggct tcttcagacc ttaccaagag
661 tggaacagaa aacccctgcc cactatggat gactccaaaa tcaagaaggt ggcaaacata
721 ttcctgtgtt cattgtccac gttgttcacc agacctataa aagacctcat aggaaaaatt
781 aagccattaa acatcttgaa catcctggca acgtgtgact ggacattcgc cggaatagtg
841 gagtctctga tattacttgc tgaactcttt ggagttttct ggacaccccc agatgtgtct
901 gctatgatcg ctcctttact tggagactac gagttgcaag ggccagaaga ccttgccgtt
961 gagctcgtac ctgtagtaat gggagggatt ggtttggtgt tgggattcac caaagagaaa
1021 attggaaaaa tgttgtcctc agcagcatca acgctcaggg cttgtaaaga tcttggtgcc
1081 tatggcttag agatactcaa attggtcatg aagtggttct tcccaaagaa agaagaggcc
1141 aatgagctag ccatggtgag agctatagag gatgctgtac tggatcttga ggcaatagaa
1201 aataatcaca tgacaactct gttgaaagac aaagacagcc tagcaaccta catgaaaaca
1261 ctagacatgg aggaggaaaa agccagaaga ttgtccacaa aatctgcatc ccctgacata
1321 gttgggacga tcaacgccct gctggctcga atagcagcgg ctaggtcact agtccacagg
1381 gccaaggagg agttatctag caggataaga ccagtggttg ttatgatatc tggcaaacca
1441 gggataggca aaactcattt ggccagggag gtggcaagaa aggtggcatc cactctcaca
1501 ggggatcaaa gagtcgggct cataccgaga aacggtgtgg accattggga tgcatacaaa
1561 ggtgagagag tcgtgctgtg ggacgactat ggcatgagca accccattca tgatgctctg
1621 cgcatacaag aattggctga tacgtgtccc cttaccttaa attgtgacag aattgaaaat
1681 aagggaaaag tttttgacag tgaagtcata ataatcacaa caaaccttgc caatccagct
1741 ccacttgatt atgtcaactt tgaggcctgt tccaggagaa ttgacttcct ggtgtacgcc
1801 gaggcaccag aagtagaaaa ggcgaaacga gactttcctg gtcaaccaga tatgtggaag
1861 gacgccttca agtcggactt ttcacatatc aagttgcaac ttgcacctca gggcggcttt
1921 gacaagaatg gcaacacccc acatgggaaa ggagtgatga agaccctcac caccggttcc
1981 ctgatcgccc gtgcatcagg cttactgcat gagaggatgg atgaatttga actccaaggc
2041 cccacagtca ccaccttcaa ttttgaccgg aacagaatcg ctgcattcag acaattggct
2101 gcagaaaaca agtatggatt ggtggacacc atgagagttg gcaatcaatt aaaaggggtg
2161 aaaaccatgg aagaactcaa acaagcaatc aagaatgtga tcatcaagag gtgccggatc
2221 atctacggcg gctccacgta tgaccttgaa tctgatggca agggcagagt tctggtggaa
2281 aaggtcaaga acacctctgt acagaccaac aacgagttgg ccggagccct gcatcacctc
2341 aaacatgccc gaatcaggta ctatgtcaaa tgtgtgcaag aagcagtcta ctctattata
2401 caaatcgccg gcgctgcgtt tgtcaccaca cgcatagtac gccgcatgaa catacaagag
2461 ctttggtcga agccaccatt agaccaaaat gaatcagagg ctaaggaaga ggcccccaag
2521 tcagaagatg acgagttcat catatcttct aaggacatca aggaggaagg aaagaagggc
2581 aaaaacaaaa ctggccgtgg caagaaacat actgcattct ctagcaaggg cttgagcgat
2641 gaggagtatg acgagtacaa gaggataaga gaagagagaa atgggaagta ctctatagag
2701 gagtatcttc aagacagaga caggtactat gaggaactcg ccatcgccaa ggccacggaa
2761 gaagacttct gtgaggagga ggagatcaaa atccgtcaga ggatcttccg tcccaccagg
2821 aagcaaagga aggaagagag ggtcacacta gggctagtaa ctggttcaga aatcagaaaa
2881 agaaaccctg atgacttcaa acctaaaggg aaactgtggg ctgatgacaa cagaagtgtt
2941 gattacaatg agaaactgga ctttgaggcc cccccaagca tatggtctag gattgtgagt
3001 tttggttctg gttggggctt ctgggtgtca ccaagcctgt tcataacatc aactcacgta
3061 atccctgcag gcataacaga ggcatttgga gtccccatca aacaaatcca ggtccacaaa
3121 tcaggtgaat tttgtcggtt cagattccca aaaccaatta gatcagatgt gacaggaatg
3181 atcttggaag aaggtgcgcc tgagggcacc gtggcaaccg tgctcatcaa acgccctacc
3241 ggagagctca tgccccttgc agccagaatg ggaacacacg caaccatgaa aattcagggc
3301 cgcatggttg gcgggcagat gggtatgttg ctcactggtt caaatgctaa aggaatggat
3361 ttgggaacaa ctcctggtga ttgtggctgt ccctacatct acaaaagggg caatgactat
3421 atagtcattg gggtgcacac agcagcagcc cgtggtggaa acaccgtcat ctgtgccaca
3481 cagggaagtg agggtgaggc aactcttgag ggtggagatg acaaaggaac atactgtggg
3541 gcacccattc taggccctgg gggggcacca aaattgagca ccaaaaccaa attttggagg
3601 tcatcgaaca cgcctcttcc accagggacg tatgagcctg cctacctcgg tggccgtgac
3661 ccgcgtgtta agggtgggcc ctccttgcag caggtaatga gagatcagtt gaagccattc
3721 accgagccca ggggtaaacc tccaagacca agtgtgttgg aagcagctaa acaaaccatc
3781 atcaatgtcc tcgaacaaac cctggaccct ccacaaaaat ggacatacgc acaggcgtgt
3841 gcttcacttg acaaaaccac ctccagcggg catccccacc acgtccgaaa gaatgaattc
3901 tggaatggtg agaccttcac tggtaaattg gcagaccaag catcaaaagc aaatctaatg
3961 tttgaggaag ggaaacacat gacaccagtg tatacagcag ccctcaagga tgagctggtc
4021 aagactgaca aagtctatgg aaagatcaag aagagactgc tctggggctc tgacttgtcc
4081 accatgatcc ggtgcgccag gtcctttggt gggctcatgg atgagatgaa agcacactgc
4141 atatcactcc cagtccgagt tggcatgaac atgaatgaag atggtccaat aatatttgag
4201 aagcactcca gatataagta tcactatgat gcagattact cccgctggga ttcaacacaa
4261 cagagggtag tactagcagc agccttggag atcatggtca ggttctctgc agagccacaa
4321 ttggcacaaa tagtcgctga ggatctgctg gcccccagtg tggtagatgt aggagacttt
4381 aaaatttcaa taaatgaagg gctcccctct ggtgtaccat gcacttctca atggaattcc
4441 atcgcacact ggctgctaac cctctgcgcc ttgtctgaag tcaccaaact gtcccctgac
4501 attgtacagg caaattccat gttctcattt tacggtgatg acgagattgt cagcaccgat
4561 ataaaattgg accctgaaaa gttaaccacc aaattgaagg agtacggcct gaaaccaact
4621 cgcccagaca aaaccgaggg acccctgatc atcagtgagg atttgaacgg actcactttc
4681 ctccggagga cggtgactcg tgacccagct ggctggtttg gaaaattgga ccaaagctca
4741 atattgaggc agatgtactg gactagagga ccaaatcatg aagaccccaa tgagacaatg
4801 ataccccact ctcaaagacc catacagctc atggcactgc ttggtgaggc ctcccttcac
4861 ggaccctctt tctacagcaa aattagtaag ttggtcataa ctgaactcaa agaaggtggg
4921 atggactttt acgtgccaag gcaggaaccc atgttcaggt ggatgaggtt ttctgacttg
4981 agcacgtggg agggcgatcg caatctggct cccaattttg tgaatgaaga tggcgtcgaa
5041 tgacgccgct ccatcgaatg atggtgcagc tagtctcgta ccagaggcca ttaatgagac
5101 tatgccattg gaacccgttg ctggcgcatc tattgctgcc ccagtggcgg gacaaactaa
5161 cataattgac ccctggataa gaacaaattt tgtgcaagcc cctaatggag agtttacagt
5221 atcaccgaga aattcccctg gagagattct attaaattta gagttgggac cagatttgaa
5281 tccttatttg gcccatctat caaggatgta caatggatac gctggaggtg ttgaggtgca
5341 agtgcttctt gctgggaacg cgttcacagc aggaaaaata ttatttgcag caatcccacc
5401 caactttcct gtagatatga tcagcccagc tcaaattact atgcttcccc atttgattgt
5461 agatgttagg acattggaac ctattatgat acccttacct gatgttagga atgtgttcta
5521 tcattttaat aatcaacccc aacctaggat gagattagtg gctatgctct ataccccatt
5581 gagatctaat ggttcaggag atgatgtctt tactgtgtct tgtagagtgt tgactaggcc
5641 aacccctgac tttgaattca tttacctagt gcctccctct gtagagtcca aaactaaacc
5701 attcacactt ccaatattga ccatttctga actaaccaac tcccggtttc ccatcccaat
5761 tgagcaactg tacacggccc caaatgagaa taatgttgtg cagtgtcaaa atggaaggtg
5821 caccttggat ggagagcttc agggcaccac ccagctgcta tcaagtgcag tttgctcgta
5881 caggggcagg actgtggcta acagtgggga caattgggac cagaatttgc tccagctgac
5941 ctacccaagc ggtgcaagct atgaccccac tgatgaagta ccagcaccct tgggcaccca
6001 ggatttcagt gggatattgt atggggtgtt aacccaagac aatgtaagtg agggtacagg
6061 ggaggccaaa aatgctaagg gagtatacat atccaccacc agtggaagat tcaccccaaa
6121 aattgggaca attggattgc attcaataac tgaaaatgtg caccccaatc agcaatcacg
6181 gttcaccccc gttggagtcg ctcagaatga aaacaccccc ttccagcaat gggttctacc
6241 acactacgca ggtgctctcg ctctaaatac caatttggca cccgctgttg ccccgacttt
6301 ccctggcgag caattactgt tcttcaggtc ccgtgttcca tgtgttcaag gtctgcgggg
6361 gcaggatgct ttcatagatt gtctcctacc tcaagagtgg gtgaaccatt tttatcaaga
6421 ggctgctccc tcccaagcag acgttgccct catcaggtat gtcaaccctg atactggtcg
6481 cacgttgttt gaggccaaat tgcacaggtc aggtttcatt actgtatcac acactggtac
6541 ctaccctctt gtggtccccc caaatggtca tttcaggttt gactcttggg ttaaccaatt
6601 ctactcactc gcccccatgg gaactggcaa tgggcgtaga agagttcaat aatggcagga
6661 gcatttatag ctggtctagc cggtgacatg ctgacttctg ctgttggttc actgacctct
6721 gcaggagcca atgccatcaa tcagaaattg aattttgatt acaataaaca actccaaaat
6781 gcatcctttc aacatgataa ggaaatgttg caggcccaaa ttgatgctac aaagaagctc
6841 caatcagaaa tgattgcaat taagcatggg gttctgaccg cgggcggctt ttccccagct
6901 gatgcagcca gaggggcagt caacgcccca atgactcgag tgttggattg gtcagggaca
6961 cgctactacg ctccaaattc tgtgcaaacc accagttatt ctgggcaatt caccccctcg
7021 cctgtccatc gggcgcaggt gaagtcccct tccaattcat ctcagcggac tgcagctcca
7081 agcagtatcc gcagcctgtc aacccaatca acttctttag gctccacctc ctcagagggg
7141 tcctctacaa cctcctctag ttcgaggaca gcagactggg tgcaacaaca aagggctctt
7201 agcccgtaca tgcagggagc cctgcagacg gcatacgtca caccgccgtc tagtagggct
7261 tccagtatga gctctgtctc aacagtgccc aaaggggttt tggactcctg gacgcctgtg
7321 tttaacacac gcaggcagcc gctgtttgca cacctcagga agagggggga gtcacaggct
7381 tagtgaaaag
//