Typing tool
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Typing tool
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Complete norovirus genomes
| MK756036 | GII.4 Sydney | |
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| GII.P16 |
ORF1: 1..5098
ORF2: 5079..6701
ORF3: 6701..7507
LOCUS MK756036 7507 bp RNA linear VRL 11-APR-2019
DEFINITION Norovirus GII isolate Hu/US/2016/GII.P16-GII.4 Sydney/Alameda0788
nonstructural polyprotein (ORF1) gene, partial cds; and VP1 (ORF2)
and VP2 (ORF3) genes, complete cds.
ACCESSION MK756036
VERSION MK756036.1
KEYWORDS .
SOURCE Norovirus GII
ORGANISM Norovirus GII
Viruses; Riboviria; Orthornavirae; Pisuviricota; Pisoniviricetes;
Picornavirales; Caliciviridae; Norovirus; Norwalk virus.
REFERENCE 1 (bases 1 to 7507)
AUTHORS Barclay,L., Cannon,J.L., Wikswo,M.E., Phillips,A., Browne,H.,
Montmayeur,A.M., Tatusov,R.L., Burke,R.M., Hall,A.J. and Vinje,J.
TITLE Emergence and characterization of multiple viruses associated with
a novel GII.P16 polymerase in the United States, 2015-2018
JOURNAL Unpublished
REFERENCE 2 (bases 1 to 7507)
AUTHORS Barclay,L., Cannon,J.L., Johnston,S.H., Montmayeur,A.M.,
Tatusov,R.L., Chhabra,P. and Vinje,J.
TITLE Direct Submission
JOURNAL Submitted (05-APR-2019) Division of Viral Diseases, Centers for
Disease Control and Prevention, 1600 Clifton Road NE, Atlanta, GA
30329, USA
COMMENT ##Assembly-Data-START##
Assembly Method :: Geneious v. R10; SPAdes v. 3.6
Sequencing Technology :: Illumina
##Assembly-Data-END##
FEATURES Location/Qualifiers
source 1..7507
/organism="Norovirus GII"
/mol_type="genomic RNA"
/strain="Alameda0788"
/isolate="Hu/US/2016/GII.P16-GII.4 Sydney/Alameda0788"
/isolation_source="stool"
/host="Homo sapiens"
/db_xref="taxon:122929"
/country="USA"
/collection_date="11-May-2016"
/note="genotype: GII.P16-GII.4 Sydney"
gene <1..5098
/gene="ORF1"
CDS <1..5098
/gene="ORF1"
/codon_start=2
/product="nonstructural polyprotein"
/protein_id="QBW96062.1"
/translation="KMASNDATVAVACNNNNDKEKSSGEGLFTNMSSTLKKALGARPK
QPAPRDEPQKPSRPPTPELVKRIPPPPPNGEVEEEPVIRYEVKSGISGLPELTTVPQP
DVANTAFSVPPLSLRENREAKEPLTGAILEMWDGEIYHYGLYVEKGLVLGVHKPPAAI
SMARVELTPLSLYWRVVYTPQYLISPETLRRLNGEAFPYTAFDNNCYAFCCWVLDLND
SWLSRRMVQRTTGFFRPYQEWNRKPLPTMDDSKIKKVANIFLCSLSTLFTRPIKDLIG
KIKPLNILNILATCDWTFAGIVESLILLAELFGVFWTPPDVSAMIAPLLGEYELQGPE
DLAVELVPVVMGGIGLVLGFTKEKIGKMLSSAASTLRACKDLGAYGLEILKLVMKWFF
PKKEEANELAMVRAIEDAVLDLEAIENNHMTTLLKDKDSLATYMKTLDMEEEKARRLS
TKSASPDIVGTINALLARIAAARSLVHRAKEELSSRIRPVVVMISGKPGIGKTHLARE
VARKVASTLTGDQRVGLIPRNGVDHWDAYKGERVVLWDDYGMSNPIHDALRIQELADT
CPLTLNCDRIENKGKVFDSEVIIITTNLANPAPLDYVNFEACSRRIDFLVYAEAPEVE
KAKRDFPGQPDMWKDAFKPDFSHIKLQLAPQGGFDKNGNTPHGKGVMKTLTTGSLIAR
ASGLLHERMDEFELQGPAITTFNFDRNRITAFRQLAAENKYGLVDTMKVGNQLKGVKT
MEELKQAIRNVTIKRCRIIYGGSTYDLESDGKGKVLVEKVKNTSVQTNNELAGALHHL
KHARIRYYVKCVQEAIYSIIQIAGAAFVTTRIARRMNIQELWSKPQLDQNESETKEEA
PKSEDDEFIISSKDIKEEGKKGKNKTGRGKKHTAFSSKGLSDEEYDEYKRIREERNGK
YSIEEYLQDRDRYYEELAIAKATEEDFCEEEEIKIRQRIFRPTRRQRKEERATLGLVT
GSEIRKRNPDDFKPKGKLWADDNRSVDYNEKLDFEAPPSIWSRIVSFGSGWGFWVSPS
LFITSTHVIPAGITEAFGVPIKQIQIHKSGEFCRFRFPKPIRPDVTGMILEEGAPEGT
VATVLIKRPTGELMPLAARMGTHATMKIQGRMVGGQMGMLLTGSNAKGMDLGTTPGDC
GCPYIYKRGNDYIAIGVHTAAARGGNTVICATQGSEGEATLEGGDDKGTYCGAPILGP
GGAPKLSTKTKFWRSSNTPLPPGTYEPAYLGGRDPRVKGGPSLQQVMRDQLKPFTEPR
GKPPRPSVLEAAKQTIINVLEQTLDPPQKWTYAQACASLDKTTSSGHPHHVRKNEFWN
GETFTGKLADQASKANLMFEEGKHMTPVYTAALKDELVKTEKIYGKIKKRLLWGSDLS
TMIRCARSFGGLMDEMKAHCISLPVRVGMNMNEDGPIIFEKHSRYKYHYDADYSRWDS
TQQRAVLAAALEIMIRFSAEPQLAQIVAEDLLAPSVVDVGDFKITINEGLPSGVPCTS
QWNSIAHWLLTLCALSEVTKLSPDIIQANSMFSFYGDDEIVSTDIKLDPEQLTAKLKE
YGLKPTRPDKTEGPLIISEDLHGLTFLRRTVTRDPAGWFGKLDQSSILRQMYWTRGPN
HEDPNETMIPHSQRPIQLMALLGEASLHGPSFYSKISKLVITELKEGGMDFYVPRQEP
MFRWMRFSDLSTWEGDRNLAPNFVNEDGVE"
mat_peptide <1..994
/gene="ORF1"
/product="p48"
mat_peptide 995..2092
/gene="ORF1"
/product="NTPase"
mat_peptide 2093..2623
/gene="ORF1"
/product="p22"
mat_peptide 2624..3022
/gene="ORF1"
/product="VPg"
mat_peptide 3023..3565
/gene="ORF1"
/product="Pro"
mat_peptide 3566..5095
/gene="ORF1"
/product="RdRp"
gene 5079..6701
/gene="ORF2"
CDS 5079..6701
/gene="ORF2"
/note="major capsid protein"
/codon_start=1
/product="VP1"
/protein_id="QBW96063.1"
/translation="MKMASSDANPSDGSAANLVPEVNNEVMALEPVVGAAIAAPVAGQ
QNVIDPWIRNNFVQAPGGEFTVSPRNAPGEILWSAPLGPDLNPYLSHLARMYNGYAGG
FEVQVILAGNAFTAGKIIFAAVPPNFPTEGLSPSQVTMFPHIIVDVRQLEPVLIPLPD
VRNNFYHYNQSNDSTIKLIAMLYTPLRANNAGDDVFTVSCRVLTRPSPDFDFIFLVPP
TVESRTKPFSVPVLTVEEMTNSRFPIPLEKLFTGPSSAFVVQPQNGRCTTDGVLLGTT
QLSPVNICTFRGDVTHITGSRNYTMNLASQNWNNYDPTEEIPAPLGTPDFVGKIQGML
TQTTRTDGSTRGHKATVYTGSADFAPKLGRVQFETDTDHDFETNQNTKFTPVGVIQDG
STTHRNEPQQWVLPSYSGRNTHNVHLAPAVAPTFPGEQLLFFRSTMPGCSGYPNMDLD
CLLPQEWVQYFYQEAAPAQSDVALLRFVNPDTGRVLFECKLHKSGYVTVAHTGQHDLV
IPPNGYFRFDSWVNQFYTLAPMGNGTGRRRVV"
gene 6701..7507
/gene="ORF3"
CDS 6701..7507
/gene="ORF3"
/note="minor structural protein; small basic protein"
/codon_start=1
/product="VP2"
/protein_id="QBW96064.1"
/translation="MAGAFFAGLASDVLGSGLGSLINAGAGAINQKVEFENNRKLQQA
SFQFSSNLQQASFQHDKEMLQAQIEATKKLQQEMMKVKQAVLLEGGFSETDAARGAIN
APMTKALDWSGTRYWAPDARTTTYNAGRFSTPQPSGALPGRANLRDAVPARGPPNKSS
NSSTVTSVYSNQTISTRLGSTAGSGTSVSSLPSTARTRSWVEDQSRNLSPFMRGAHNI
SFVTPPSSRSSSQGTVSTVPKEILDSWTGAFNTRRQPLFAHIRKRGESRV"
ORIGIN
1 gaagatggcg tctaacgacg ctaccgttgc cgttgcttgc aacaacaaca acgacaagga
61 aaaatcttca ggtgaaggct tattcacaaa tatgtcttcc accttaaaga aagccctcgg
121 ggctaggccc aaacagcccg ccccgagaga cgaaccacaa aagccctcaa gaccaccaac
181 tcccgagttg gtcaagagga taccccctcc tccacctaat ggcgaagtag aagaagaacc
241 agtcattagg tatgaggtta agagtgggat ctctggcctg cccgagctca caacagtccc
301 ccaaccggac gtggccaaca cagcattcag tgttccacca ctgagcttga gagaaaacag
361 ggaggccaag gaaccgctaa caggggcaat attagagatg tgggatggag agatatacca
421 ctatggcctg tacgtggaga aaggcttagt gttgggtgtg cacaaaccac ctgcagccat
481 aagcatggca agagtggagc tgacgccgct gtcattgtac tggcgtgtgg tgtacactcc
541 ccaatacctc atctcccctg aaactctcag gaggctcaac ggagaggcgt tcccttacac
601 cgccttcgac aacaactgct atgccttttg ctgctgggtg ttagacctca atgactcatg
661 gcttagcagg aggatggtgc aaagaacaac gggcttcttc agaccttacc aagagtggaa
721 cagaaaaccc ctgcctacca tggatgactc caaaattaag aaggtagcaa atatattctt
781 atgttcattg tccacgttat tcaccagacc cataaaagac ctcataggaa aaattaaacc
841 attaaacata ttgaacatcc tggcaacgtg tgactggacg tttgccggaa tagtggagtc
901 tctgatatta cttgctgaac tcttcggagt tttctggaca cccccagatg tgtctgctat
961 gatcgctccc ttactcgggg aatacgagtt gcaagggcca gaagacctcg ccgttgaact
1021 cgtacctgtg gtaatgggag ggattggttt ggtgttggga ttcaccaaag agaaaattgg
1081 caaaatgttg tcctcagcag catcaacact cagggcttgc aaagatcttg gtgcctatgg
1141 cttagagata ctcaaattgg tcatgaagtg gttcttccca aagaaagagg aggccaatga
1201 gctagccatg gtgagggcca tagaggatgc cgtactagat cttgaggcaa tagaaaataa
1261 ccacatgaca accctgttga aagacaaaga cagcttagca acatacatga aaacactgga
1321 catggaggag gagaaagcca gaaggttgtc cacaaaatct gcatcccctg acatagttgg
1381 gacaatcaac gccctgctgg ctcgaatagc agcggccagg tcattagtcc acagggccaa
1441 ggaagagcta tctagcagga taagaccagt agttgttatg atatctggca aaccaggaat
1501 aggcaaaact catctggcca gggaggtggc aagaaaggtg gcatccactc tcacagggga
1561 tcaaagagtc ggactcatac caagaaacgg tgtggaccat tgggatgcat acaaaggtga
1621 gagagtcgtg ctgtgggacg actatggcat gagtaacccc attcatgatg ctcttcgcat
1681 acaagaattg gctgatacgt gtccccttac cttaaattgt gacagaattg aaaataaggg
1741 aaaagttttt gacagtgaag tcataataat cacaacaaac cttgccaatc cagccccact
1801 tgattatgtc aactttgagg cctgttccag gagaattgat ttcctggtgt acgctgaggc
1861 accagaagta gaaaaggcaa aacgggactt tcctggtcag ccagatatgt ggaaggacgc
1921 cttcaagccg gacttttcac acatcaagct acagcttgca cctcagggcg gctttgacaa
1981 gaatggcaac accccacatg ggaaaggagt gatgaagacc ctcactaccg gttctctgat
2041 tgcccgtgca tcaggcctac tgcatgagag gatggatgaa tttgaactcc aaggtcccgc
2101 aatcaccacc ttcaatttcg accggaacag aatcacagca ttcagacaat tggctgcaga
2161 aaacaagtat ggattggttg ataccatgaa agttggcaat caactaaaag gagtgaaaac
2221 catggaagaa ctcaaacaag caatcaggaa tgtgaccatc aagaggtgcc ggatcatcta
2281 cggtggctcc acgtacgacc ttgaatctga tggcaagggc aaagttttgg tggaaaaggt
2341 caagaacacc tctgtacaga ccaacaacga gttggccggg gccctgcacc atctcaaaca
2401 cgcccgaatc aggtactatg tcaaatgtgt gcaagaagca atctactcca tcatacaaat
2461 tgccggcgct gcgtttgtta ccacgcgcat tgcacgccgc atgaacatac aagaactctg
2521 gtcgaagcca caattagatc aaaatgaatc agagactaag gaagaggccc ccaagtcaga
2581 agacgacgag ttcatcatat catctaagga catcaaggag gaaggaaaga agggcaaaaa
2641 caaaactggc cgtggcaaga aacacactgc attctccagc aagggtttga gcgatgagga
2701 gtatgacgag tacaagagga taagagaaga gagaaatggg aagtactcta tagaggagta
2761 tcttcaagat agagacaggt actatgagga gctcgccatt gccaaggcca cagaagaaga
2821 cttctgtgaa gaggaggaga tcaaaatccg tcagagaatt ttccgtccca ccaggagaca
2881 aagaaaggaa gagagggcca cattagggct agtaacaggt tcagaaatca gaaaaagaaa
2941 ccctgatgac ttcaaaccca aagggaagct gtgggccgat gacaacagaa gtgttgacta
3001 caatgagaaa ctggacttcg aggccccccc aagcatatgg tctaggatcg tgagctttgg
3061 ttctggctgg ggcttctggg tatcaccaag cctgttcata acatcaactc atgtaatccc
3121 cgcaggcata acagaagcgt ttggagtccc catcaaacaa attcagatcc acaaatcagg
3181 tgaattttgc cgattcagat tcccaaaacc aattagacca gatgtgacag gaatgatctt
3241 ggaagaaggt gcgcctgaag gcaccgtggc aactgtgctc atcaaacgcc ccaccggaga
3301 gctcatgcct cttgcagcca gaatgggaac acacgcaacc atgaaaattc aaggccgcat
3361 ggttggcgga cagatgggta tgttgctcac tggatcaaat gctaaaggaa tggatttggg
3421 aacaactcct ggtgactgtg gctgtcctta catctataaa aggggcaatg actacatagc
3481 cataggggtg cacactgcag cagcccgtgg tggaaacacc gtcatctgtg ctacacaggg
3541 aagtgagggt gaggcaactc tcgagggtgg agatgacaaa ggaacatact gtggggcacc
3601 cattctaggc cctgggggtg caccaaaatt gagcaccaaa accaaatttt ggaggtcatc
3661 gaacacgccc cttccaccag ggacatatga gcctgcctac ctcggtggcc gtgatccgcg
3721 tgttaagggt gggccatcct tgcagcaggt aatgagagac cagttgaagc cattcactga
3781 acccaggggc aaacctccaa gaccaagtgt attggaagca gccaaacaaa ccattatcaa
3841 tgtcctcgaa caaaccctgg accctccaca aaaatggaca tacgcacagg cgtgtgcctc
3901 acttgacaaa accacctcca gcgggcatcc ccatcacgtc cgaaagaatg aattctggaa
3961 tggtgagacc ttcactggta aattggcaga ccaagcatca aaagcaaacc taatgtttga
4021 ggaagggaaa cacatgacac cagtgtatac agcagcactc aaggatgagc tagtcaagac
4081 tgagaaaatc tatggaaaga tcaagaagag actgctctgg ggctctgact tgtccaccat
4141 gatccggtgc gctaggtcat ttggtgggct catggacgag atgaaggcac actgcatatc
4201 actcccagta cgagttggca tgaatatgaa tgaagatggc ccaataatat ttgagaaaca
4261 ttccagatat aaataccact atgatgcaga ctactctcgt tgggattcaa cacaacagag
4321 ggcagtacta gcagcagctt tggaaatcat gatcagattc tctgcagaac cacaattggc
4381 acaaatagtc gctgaggatc tgctggcccc tagtgtagta gatgtaggag actttaaaat
4441 cacaataaat gaagggctcc catctggtgt gccatgcact tctcaatgga actccatcgc
4501 acactggctg ctaactctct gtgccttgtc tgaagtcacc aaactgtccc ctgacattat
4561 acaagcaaat tccatgttct cattttacgg tgatgacgag attgtcagca ccgacataaa
4621 attggaccct gaacagttaa ccgccaagtt gaaggagtac ggcctgaaac caacccgccc
4681 agacaagacc gaggggcccc tgatcatcag tgaagatttg cacggactca ctttcctccg
4741 aaggacggtg actcgtgacc cagctggctg gtttggaaaa ctggaccaaa gctcaatttt
4801 gaggcagatg tactggacta gagggccaaa tcatgaagac cccaatgaga caatgatacc
4861 ccattctcaa agacccatac agctcatggc actgcttggt gaagcctctc ttcacggacc
4921 ctctttctac agtaaaatca gtaaattggt cataactgaa ctcaaagaag gtgggatgga
4981 cttttacgtg ccaaggcagg aacccatgtt caggtggatg aggttttctg acttgagcac
5041 gtgggagggc gatcgcaatc tggctcccaa ttttgtgaat gaagatggcg tcgagtgacg
5101 ccaacccatc tgatgggtcc gcagccaacc tcgtaccaga ggtcaacaat gaggttatgg
5161 ctttggagcc cgttgttggt gccgctattg cggcacctgt agcgggccaa caaaatgtaa
5221 ttgacccctg gattagaaat aattttgtac aagcccctgg tggggagttc acagtatccc
5281 ctagaaacgc tccaggtgaa atactatgga gcgcgcccct aggccccgac ctaaatccct
5341 acctatccca tttggccaga atgtacaatg gttatgcagg tggttttgaa gtgcaggtaa
5401 ttctcgcggg gaacgcgttc accgccggga agatcatatt tgcagcagtc ccaccaaatt
5461 ttccaactga aggcttaagt cctagccaag tcactatgtt cccccatata atagtagatg
5521 ttagacaatt agaacctgtg ctgattccct tacccgatgt taggaataat ttctatcatt
5581 ataatcagtc aaatgactcc actattaagt tgatagcaat gttgtataca ccacttaggg
5641 ctaataatgc tggggatgat gttttcacag tttcgtgccg agttctcacg agaccatccc
5701 ccgattttga tttcatattt ttagtgccac ccacagttga gtcaagaact aaaccattct
5761 ctgtcccagt tttaactgtt gaggagatga ccaattcaag attccccatt cctttggaaa
5821 agttgttcac gggccccagc agtgcctttg ttgttcaacc acaaaacggc aggtgcacaa
5881 ctgatggcgt gctcctaggc accacccaac tgtctcctgt caacatctgc accttcagag
5941 gggatgtcac ccacatcaca ggtagtcgca actacacaat gaatttggct tctcaaaatt
6001 ggaacaatta tgacccaaca gaagaaatcc cagcccctct aggaactcca gattttgtgg
6061 ggaagattca aggcatgctc acccaaacca caaggacaga tggttcaaca cgcggccaca
6121 aagctacagt gtacactggg agcgccgact ttgctccaaa actgggtaga gttcaatttg
6181 aaactgacac agaccatgat tttgaaacta atcaaaacac aaagttcacc ccagtcggtg
6241 tcatccaaga tggtagcacc acccaccgaa acgaacccca acagtgggtg ctcccaagtt
6301 actcaggcag aaatactcac aatgtacatc tggcccccgc tgtagccccc acctttccgg
6361 gtgagcaact tctcttcttc agatccacca tgcccggatg cagcgggtac cccaacatgg
6421 atttggactg tctgctcccc caggaatggg tgcagtactt ctaccaagag gcagccccag
6481 cacaatctga tgtggctctg ctaagatttg tgaatccaga cacaggtagg gttttgtttg
6541 agtgcaagct tcacaaatca ggctatgtta cagtggctca cactggccaa catgatttgg
6601 ttatccctcc caatggttac tttaggtttg attcctgggt caaccagttc tacacgcttg
6661 cccccatggg aaatggaacg gggcgtagac gtgtagtata atggctggag ctttctttgc
6721 tggattggca tctgatgtcc ttggctctgg acttggttcc ctcatcaatg ctggagctgg
6781 ggccatcaac caaaaagttg agtttgaaaa taacagaaaa ttgcaacaag catccttcca
6841 atttagcagc aatctgcaac aggcttcctt tcaacatgat aaagagatgc tccaagcaca
6901 aattgaggcc accaaaaagc tacaacagga aatgatgaaa gttaagcagg cagtgctcct
6961 agagggtggg ttctctgaga cagatgcagc ccgcggggca attaacgccc ccatgacaaa
7021 agctttggat tggagcggga caaggtactg ggctcccgat gctaggacta caacatacaa
7081 tgcaggccgc ttttccaccc ctcaaccatc gggggcactg ccaggaagag ctaatcttag
7141 ggatgctgtc cctgctcggg gaccccccaa caaatcttct aactcttcta ctgtcacctc
7201 tgtgtactca aatcaaacta tttcaacgag acttggttct acagctggtt ctggaaccag
7261 tgtctcgagc ctcccgtcaa ctgcaaggac taggagctgg gttgaggatc aaagtaggaa
7321 tttgtcacct ttcatgaggg gggcccacaa catatcattt gtcaccccac catctagcag
7381 atcctctagc caaggcacag tctcaaccgt gcctaaagag attttggact cctggactgg
7441 cgctttcaac acgcgcaggc agcctctctt cgctcacatt cgtaagcgag gggagtcacg
7501 ggtgtaa
//