Typing tool
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Typing tool
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Complete norovirus genomes
| MK756033 | GII.4 Sydney | |
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| GII.P16 |
ORF1: 1..5096
ORF2: 5077..6699
ORF3: 6699..7505
LOCUS MK756033 7505 bp RNA linear VRL 11-APR-2019
DEFINITION Norovirus GII isolate Hu/US/2016/GII.P16-GII.4 Sydney/Alameda0771
nonstructural polyprotein (ORF1) gene, partial cds; and VP1 (ORF2)
and VP2 (ORF3) genes, complete cds.
ACCESSION MK756033
VERSION MK756033.1
KEYWORDS .
SOURCE Norovirus GII
ORGANISM Norovirus GII
Viruses; Riboviria; Orthornavirae; Pisuviricota; Pisoniviricetes;
Picornavirales; Caliciviridae; Norovirus; Norwalk virus.
REFERENCE 1 (bases 1 to 7505)
AUTHORS Barclay,L., Cannon,J.L., Wikswo,M.E., Phillips,A., Browne,H.,
Montmayeur,A.M., Tatusov,R.L., Burke,R.M., Hall,A.J. and Vinje,J.
TITLE Emergence and characterization of multiple viruses associated with
a novel GII.P16 polymerase in the United States, 2015-2018
JOURNAL Unpublished
REFERENCE 2 (bases 1 to 7505)
AUTHORS Barclay,L., Cannon,J.L., Johnston,S.H., Montmayeur,A.M.,
Tatusov,R.L., Chhabra,P. and Vinje,J.
TITLE Direct Submission
JOURNAL Submitted (05-APR-2019) Division of Viral Diseases, Centers for
Disease Control and Prevention, 1600 Clifton Road NE, Atlanta, GA
30329, USA
COMMENT ##Assembly-Data-START##
Assembly Method :: Geneious v. R10; SPAdes v. 3.6
Sequencing Technology :: Illumina
##Assembly-Data-END##
FEATURES Location/Qualifiers
source 1..7505
/organism="Norovirus GII"
/mol_type="genomic RNA"
/strain="Alameda0771"
/isolate="Hu/US/2016/GII.P16-GII.4 Sydney/Alameda0771"
/isolation_source="stool"
/host="Homo sapiens"
/db_xref="taxon:122929"
/country="USA"
/collection_date="21-Apr-2016"
/note="genotype: GII.P16-GII.4 Sydney"
gene <1..5096
/gene="ORF1"
CDS <1..5096
/gene="ORF1"
/codon_start=3
/product="nonstructural polyprotein"
/protein_id="QBW96053.1"
/translation="MASNDATVAVACNNNNDKEKSSGEGLFTNMSSTLKKALGARPKQ
PAPRDEPQKPPRPPTPELVKRIPPPPPNGEEEGEPVIRYEVKSGISGLPELTTVPQPD
VANTAFSVPPLSLRENREAKEPLTGAILEMWDGEIYHYGLYVEKGLVLGVHKPPAAIS
MARVELTPLSLYWRVVYTPQYLISPETLRRLNGEAFPYTAFDNNCYAFCCWVLDLNDS
WLSRRMVQRTTGFFRPYQEWNRKPLPTMDDSKIKKVANIFLCSLSTLFTRPIKDLIGK
IKPLNVLNILATCDWTFAGIVESLILLAELFGVFWTPPDVSAMIAPLLGEYELQGPED
LAVELVPVVMGGIGLVLGFTKEKIGKMLSSAASTLRACKDLGAYGLEILKLVMKWFFP
KKEEANELAMVRAIEDAVLDLEAIENNHMTTLLKDKDSLATYMKTLDMEEEKARRLST
KSASPDIVGTINALLARIAAARSLVHRAKEELSSRIRPVVVMISGKPGIGKTHLAREV
ARKVASTLTGDQRVGLIPRNGVDHWDAYKGERVVLWDDYGMSNPIHDALRIQELADTC
PLTLNCDRIENKGKVFDSEVIIITTNLANPAPLDYVNFEACSRRIDFLVYAEAPEVEK
AKRDFPGQPDMWKDAFKPDFSHIKLQLAPQGGFDKNGNTPHGKGVMKTLTTGSLIARA
SGLLHERMDEFELQGPTITTFNFDRNRITAFRQLAAENKYGLVDTMKVGNQLKGVKTM
EELKQAIRNVTIKRCRIIYGGSTYDLESDGKGKVLVEKVKNTSVQTNNELAGALHHLK
HARIRYYVKCVQEAIYSIIQIAGAAFVTTRIARRMNIQELWSKPQLDQNESETKEEAP
KSEDDEFIISSKDIKEEGKKGKNKTGRGKKHTAFSSKGLSDEEYDEYKRIREERNGKY
SIEEYLQDRDRYYEELAIAKATEEDFCEEEEIKIRQRIFRPTRKQRKEERATLGLVTG
SEIRKRNPDDFKPKGKLWADDNRSVDYNEKLDFEAPPSIWSRIVSFGSGWGFWVSPSL
FITSTHVIPAGITEAFGVPIKQIQIHKSGEFCRFRFPKPIRPDVTGMILEEGAPEGTV
ATVLIKRPTGELMPLAARMGTHATMKIQGRMVGGQMGMLLTGSNAKGMDLGTTPGDCG
CPYIYKRGNDYIVIGVHTAAARGGNTVICATQGSEGEATLEGGDDKGTYCGAPILGPG
GAPKLSTKTKFWRSSNTPLPPGTYEPAYLGGRDPRVKGGPSLQQVMRDQLKPFTEPRG
KPPRPSVLEAAKQTIINVLEQTLDPPQKWTYAQACASLDKTTSSGHPHHARKNEFWNG
ETFTGKLADQASKANLMFEEGKHMTPVYTAALKDELVKTEKIYGKIKKRLLWGSDLST
MIRCARSFGGLMDEMKAHCISLPVRVGMNMNEDGPIIFEKHSRYKYHYDADYSRWDST
QQRAVLAAALEIMVRFSAEPQLAQIVAEDLLAPSVVDVGDFKITINEGLPSGVPCTSQ
WNSIAHWLLTLCALSEVTKLSPDIIQANSMFSFYGDDEIVSTDIKLDPEQLTAKLKEY
GLKPTRPDKTEGPLIISEDLNGLTFLRRTVTRDPAGWFGKLDQSSILRQMYWTRGPNH
EDPNETMIPHSQRPIQLMALLGEASLHGPSFYSKISKLVITELKEGGMDFYVPRQEPM
FRWMRFSDLSTWEGDRNLAPNFVNEDGVE"
mat_peptide <1..992
/gene="ORF1"
/product="p48"
mat_peptide 993..2090
/gene="ORF1"
/product="NTPase"
mat_peptide 2091..2621
/gene="ORF1"
/product="p22"
mat_peptide 2622..3020
/gene="ORF1"
/product="VPg"
mat_peptide 3021..3563
/gene="ORF1"
/product="Pro"
mat_peptide 3564..5093
/gene="ORF1"
/product="RdRp"
gene 5077..6699
/gene="ORF2"
CDS 5077..6699
/gene="ORF2"
/note="major capsid protein"
/codon_start=1
/product="VP1"
/protein_id="QBW96054.1"
/translation="MKMASSDANPSDGSAANLVPEVNNEVMALEPVVGAAIAAPVAGQ
QNVIDPWIRNNFVQAPGGEFTVSPRNAPGEILWSAPLGPDLNPYLSHLARMYNGYAGG
FEVQVILAGNAFTAGKIIFAAVPPNFPTEGLSPSQVTMFPHIIVDVRQLEPVLIPLPD
VRNNFYHYNQSNDSTIKLIAMLYTPLRANNAGDDVFTVSCRVLTRPSPDFDFIFLVPP
TVESRTKPFSVPVLTVEEMTNSRFPIPLEKLFTGPSSAFVVQPQNGRCTTDGVLLGTT
QLSPVNICTFRGDVTHITGSRNYTMNLASQNWNNYDPTEEIPAPLGTPDFVGKIQGML
TQTTRTDGSTRGHKATVYTGSADFAPKLGRVQFETDTDHDFEANQNTKFTPVGVIQDG
STTHRNEPQQWVLPSYSGRNTHNVHLAPAVAPTFPGEQLLFFRSTMPGCSGYPNMDLD
CLLPQEWVQYFYQEAAPAQSDVALLRFVNPDTGRVLFECKLHKSGYVTVAHTGQHDLV
IPPNGYFRFDSWVNQFYTLAPMGNGTGRRRVV"
gene 6699..7505
/gene="ORF3"
CDS 6699..7505
/gene="ORF3"
/note="minor structural protein; small basic protein"
/codon_start=1
/product="VP2"
/protein_id="QBW96055.1"
/translation="MAGAFFAGLASDVLGSGLGSLINAGAGAINQKVEFENNRKLQQA
SFQFSSNLQQASFQHDKEMLQAQIEATKKLQQEMMKVKQAVLLEGGFSETDAARGAIN
APMTKALDWSGTRYWAPDARTTTYNAGRFSTPQPSGALPGRANLRDAVPARGPSNKSS
NSSTVTSVYSNQTISTRLGSTAGSGTSVSSLPSTARTRSWVEDQSRNLSPFMRGAHNI
SFVTPPSSRSSSQGTVSTVPKEILDSWTGAFNTRRQPLFAHIRKRGESRV"
ORIGIN
1 agatggcgtc taacgacgct accgttgccg ttgcttgcaa caacaacaac gacaaggaaa
61 aatcttcagg tgaaggctta ttcacaaata tgtcttccac cttaaagaaa gccctcgggg
121 ctaggcccaa acagcccgcc ccgagagacg aaccacaaaa gcccccaagg ccaccaactc
181 ccgagttggt caagaggata ccccctcctc cacctaatgg cgaagaagaa ggagaaccag
241 tcattaggta tgaggttaag agtgggatct ctggcctgcc cgagctcaca acagtccccc
301 aaccggacgt ggccaacaca gcattcagtg ttccaccact gagcttgaga gaaaacaggg
361 aggccaagga accgctaaca ggggcaatat tagagatgtg ggatggagag atataccact
421 atggcctgta cgtggagaaa ggcttagtgt tgggtgtgca caaaccacct gcagccataa
481 gcatggcaag agtggagctg acgccgctgt cattgtactg gcgtgtggtg tacactcccc
541 aatacctcat ctcccctgaa actctcagga ggctcaacgg agaggcgttc ccttacaccg
601 ccttcgacaa caactgctat gccttttgct gctgggtgtt agacctcaat gactcatggc
661 ttagcaggag gatggtgcaa agaacaacgg gcttcttcag accttaccaa gagtggaaca
721 gaaaacccct gcctaccatg gatgactcca aaattaagaa ggtagcaaat atattcctat
781 gttcattgtc cacgttattc accagaccca taaaagacct cataggaaaa attaaaccat
841 taaacgtatt gaacatcctg gcaacgtgtg actggacgtt tgccggaata gtggaatctc
901 tgatattact tgctgaactc ttcggagttt tctggacacc cccagatgtg tctgctatga
961 tcgctccctt actcggggaa tacgagttgc aagggccaga agacctcgcc gttgaactcg
1021 tacctgtggt aatgggaggg attggtttgg tgttgggatt caccaaagag aaaattggca
1081 aaatgttgtc ctcagcagca tcaacactca gggcttgcaa agatcttggt gcctatggct
1141 tagagatact caaattggtc atgaagtggt tcttcccaaa gaaagaggag gccaatgagc
1201 tagccatggt gagggccata gaggatgccg tactagatct tgaggcaata gaaaataacc
1261 acatgacaac cctgttgaaa gacaaagaca gcttagcaac atacatgaaa acactggaca
1321 tggaggagga gaaagccaga aggttgtcca caaaatctgc atcccctgac atagttggga
1381 caatcaacgc cctgctggct cgaatagcag cggccaggtc attagttcac agggccaagg
1441 aagagctatc tagcaggata agaccagtag ttgttatgat atctggtaaa ccaggaatag
1501 gcaaaaccca tctggccagg gaggtggcaa gaaaggtggc atccactctc acaggggatc
1561 aaagagtcgg actcatacca agaaacggtg tggaccattg ggatgcatac aaaggtgaga
1621 gagtcgtgct gtgggacgac tatggcatga gtaaccccat tcatgatgct cttcgcatac
1681 aagaattggc tgatacgtgc ccccttacct taaattgtga cagaattgaa aataagggaa
1741 aagtttttga cagtgaagtc ataataatta caacaaacct tgccaatcca gccccacttg
1801 attatgtcaa ctttgaggcc tgttccagga gaattgattt cctggtgtac gctgaggcac
1861 cagaagtaga aaaggcaaaa cgggactttc ctggtcagcc agatatgtgg aaggacgcct
1921 ttaagccgga cttttcacac atcaagctac agcttgcacc tcagggcggc tttgacaaga
1981 atggcaacac cccacatggg aaaggagtga tgaagaccct cactaccggt tctctgattg
2041 cccgtgcatc aggcctactg catgagagga tggatgaatt tgaactccaa ggtcccacaa
2101 tcaccacctt caatttcgac cggaatagaa tcacagcatt cagacaattg gctgcagaaa
2161 acaagtatgg attggtggat accatgaaag ttggcaatca actaaaagga gtgaaaacca
2221 tggaagaact caaacaagca atcaggaatg tgaccatcaa gaggtgccgg atcatctacg
2281 gtggctccac gtacgacctt gaatctgatg gcaagggcaa agttttggtg gaaaaggtca
2341 agaacacctc tgtacagacc aacaacgagt tggccggggc cctgcaccat ctcaaacacg
2401 cccgaatcag gtactatgtc aaatgtgtgc aagaagcaat ctactccatc atacaaattg
2461 ccggcgctgc gtttgtcacc acgcgcattg cacgccgcat gaacatacaa gaactctggt
2521 cgaagccaca attagatcaa aatgaatcag agactaagga agaggccccc aagtcagaag
2581 acgacgagtt catcatatct tctaaggaca tcaaggagga aggaaagaag ggcaaaaaca
2641 aaactggccg tggcaagaaa cacactgcat tctccagcaa gggtttgagc gatgaggagt
2701 atgacgagta caagaggata agagaagaga gaaatgggaa gtactctata gaggagtatc
2761 ttcaagatag agacaggtac tatgaggagc tcgccattgc caaggccaca gaagaagact
2821 tctgtgaaga ggaggagatc aaaatccgtc agagaatttt ccgtcccacc aggaaacaaa
2881 gaaaggaaga gagggccaca ttagggctag taacaggttc agaaatcaga aaaagaaacc
2941 ctgatgactt caaacccaaa gggaagctgt gggccgatga caacagaagt gttgactaca
3001 atgagaaact ggactttgag gcccccccaa gcatatggtc taggattgtg agctttggtt
3061 ctggctgggg cttctgggta tcaccaagcc tgttcataac atcaactcat gtaatccccg
3121 caggcataac agaagcgttt ggagtcccca tcaaacaaat tcagatccac aaatcaggtg
3181 aattttgccg attcagattc ccaaaaccaa ttagaccaga tgtgacagga atgatcttgg
3241 aagaaggtgc gcctgaaggc accgtggcaa ctgtgctcat caaacgcccc accggagagc
3301 tcatgcctct tgcagccaga atgggaacac acgcaaccat gaaaattcaa ggccgcatgg
3361 ttggcggaca gatgggtatg ttgctcactg gatcaaatgc caaaggaatg gatttgggaa
3421 caactcctgg tgactgtggc tgtccttaca tctataagag gggcaatgac tacatagtca
3481 ttggggtgca cactgcagca gcccgtggtg gaaacaccgt catctgtgct acacagggaa
3541 gtgagggtga ggcaactctt gagggtggag atgacaaagg aacatactgt ggggcaccca
3601 ttctaggccc tgggggtgca ccaaaattga gcaccaaaac caaattttgg aggtcatcga
3661 acacgcccct tccaccaggg acatatgagc ctgcctacct cggtggccgt gatccgcgtg
3721 ttaagggtgg gccctccttg cagcaggtaa tgagagacca gttgaagcca ttcactgaac
3781 ccaggggcaa acctccaaga ccaagtgtat tggaagcagc caaacaaacc attatcaatg
3841 tcctcgaaca aaccctggac cctccacaaa aatggacata cgcacaggcg tgtgcctcac
3901 ttgacaaaac cacctccagc gggcatcccc atcacgcccg aaagaatgaa ttctggaatg
3961 gtgagacctt cactggtaaa ttggcagacc aagcatcaaa agcaaaccta atgtttgagg
4021 aagggaaaca catgacacca gtgtatacag cagcactcaa ggatgagcta gtcaagactg
4081 agaaaatcta tggaaagatc aagaagagac tactctgggg ctctgacttg tccaccatga
4141 tccggtgcgc taggtcattt ggtgggctca tggacgagat gaaggcacac tgcatatcac
4201 tcccagtacg agttggcatg aatatgaatg aagatggccc aataatattt gagaaacatt
4261 ccagatataa ataccactat gatgcagact actctcgttg ggattcaaca caacagaggg
4321 cagtactagc agcagctttg gaaatcatgg tcagattctc tgcagaacca caattggcac
4381 aaatagtcgc tgaggatctg ctggccccta gtgtagtaga tgtaggagac tttaaaatca
4441 caataaatga agggctccca tctggtgtgc catgcacttc tcaatggaac tccatcgcac
4501 actggctgct aactctctgt gccttgtctg aagtcaccaa actgtcccct gacattatac
4561 aagcaaattc catgttctca ttttacggtg atgacgagat tgtcagcacc gacataaaat
4621 tggaccctga acagttaacc gccaagttga aggagtacgg actgaaacca acccgcccag
4681 acaagaccga gggacccctg atcatcagtg aagatttgaa cggactcact ttcctccgaa
4741 ggacggtgac tcgtgaccca gctggctggt ttggaaaact ggaccaaagc tcaattttga
4801 gacagatgta ctggactaga ggaccaaatc atgaagaccc caatgagaca atgatacccc
4861 attctcaaag acccatacag ctcatggcac tgcttggtga agcctctctt cacggaccct
4921 ctttctacag taaaatcagt aaattggtca taactgaact caaagaaggt gggatggact
4981 tttacgtgcc aaggcaggaa cccatgttca ggtggatgag gttttctgac ttgagcacgt
5041 gggagggcga tcgcaatctg gctcccaatt ttgtgaatga agatggcgtc gagtgacgcc
5101 aacccatctg atgggtccgc agccaacctc gtaccagagg tcaacaatga ggttatggct
5161 ttggagcccg ttgttggtgc cgctattgcg gcacctgtag cgggccaaca aaatgtaatt
5221 gacccctgga ttagaaataa ttttgtgcaa gcccctggtg gggagtttac agtatcccct
5281 agaaacgctc caggtgaaat actatggagc gcgcccctag gccctgacct aaatccctac
5341 ctatcccatt tggccagaat gtacaatggt tatgcaggtg gttttgaagt gcaggtaatt
5401 ctcgcgggga acgcgttcac cgccgggaag atcatatttg cagcagtccc accaaatttt
5461 ccaactgaag gcttaagtcc tagccaagtc actatgttcc cccatataat agtagatgtt
5521 agacaattag aacctgtgct gattccctta cccgatgtta ggaataattt ttatcattat
5581 aatcagtcaa atgactccac tattaagttg atagcaatgt tgtatacacc acttagggct
5641 aataatgctg gggatgatgt tttcacagtt tcgtgccgag ttctcacgag accatccccc
5701 gattttgatt tcatattttt agtgccaccc acagttgagt caagaactaa accattctct
5761 gtcccagttt taactgttga ggagatgacc aattcaagat tccccattcc tttggaaaag
5821 ttgttcacgg gccccagcag tgcctttgtt gttcaaccac aaaacggcag gtgcacaact
5881 gatggcgtgc tcctaggcac cacccaactg tctcctgtca acatctgcac cttcagaggg
5941 gatgtcaccc acatcacagg tagtcgtaac tacacaatga atttggcttc tcaaaattgg
6001 aacaattatg acccaacaga agaaatccca gcccctctag gaactccaga ttttgtgggg
6061 aagattcaag gcatgctcac ccaaaccaca aggacagatg gttcaacacg cggccacaaa
6121 gctacagtgt acactgggag cgccgacttt gctccaaaac tgggtagagt tcaatttgaa
6181 actgacacag accatgattt tgaagctaat caaaacacaa agttcacccc agtcggtgtc
6241 atccaagatg gtagcaccac ccaccgaaac gaaccccaac agtgggtgct cccaagttac
6301 tcaggcagaa atactcacaa tgtacatctg gcccccgctg tagctcccac ctttccgggt
6361 gagcaacttc tcttcttcag atccaccatg cccggatgca gtgggtaccc caacatggat
6421 ttggactgtc tgctccccca ggaatgggtg cagtacttct accaagaggc agccccagca
6481 caatctgatg tggctctgct aagatttgtg aatccagaca caggtagggt tttgtttgag
6541 tgcaagcttc acaaatcagg ctatgttaca gtggctcaca ctggccaaca tgatttggtt
6601 atccctccca atggttactt taggtttgat tcctgggtca accagttcta cacgcttgcc
6661 cccatgggaa atggaacggg gcgtagacgt gtagtataat ggctggagct ttctttgctg
6721 gattggcatc tgatgtcctt ggctctggac ttggttccct tatcaatgct ggggctgggg
6781 ccatcaacca aaaagttgag tttgaaaata acagaaaatt acaacaagca tccttccaat
6841 ttagcagcaa tctgcaacag gcttcctttc aacatgataa agagatgctc caagcacaaa
6901 ttgaggccac caaaaagcta caacaggaaa tgatgaaagt taagcaggca gtgctcctag
6961 agggtgggtt ctctgagaca gatgcagccc gcggggcaat taacgccccc atgacaaaag
7021 ctttggattg gagcgggaca aggtactggg ctcccgatgc taggactaca acatacaatg
7081 caggccgctt ttccacccct caaccatcgg gggcactgcc aggaagagct aatcttaggg
7141 atgctgtccc tgctcgggga ccctccaaca aatcttctaa ctcttctact gtcacctctg
7201 tgtactcaaa tcaaactatt tcaacgagac ttggttctac agctggttct ggaaccagtg
7261 tctcgagcct cccgtcaact gcaaggacta ggagctgggt tgaggatcaa agtaggaatt
7321 tgtcaccttt catgaggggg gcccacaaca tatcatttgt caccccacca tccagcagat
7381 cctctagcca aggcacagtc tcaaccgtgc ctaaagagat tttggactcc tggactggcg
7441 ctttcaacac gcgcaggcag cctctcttcg ctcacattcg taagcgaggg gagtcacggg
7501 tgtaa
//