Typing tool
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Typing tool
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Complete norovirus genomes
| MK754444 | GII.4 Sydney | |
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| GII.P16 |
ORF1: 2..5101
ORF2: 5082..6704
ORF3: 6704..7477
LOCUS MK754444 7477 bp RNA linear VRL 11-APR-2019
DEFINITION Norovirus GII isolate Hu/US/2017/GII.P16-GII.4 Sydney/Baltimore0201
nonstructural polyprotein (ORF1) and VP1 (ORF2) genes, complete
cds; and VP2 (ORF3) gene, partial cds.
ACCESSION MK754444
VERSION MK754444.1
KEYWORDS .
SOURCE Norovirus GII
ORGANISM Norovirus GII
Viruses; Riboviria; Orthornavirae; Pisuviricota; Pisoniviricetes;
Picornavirales; Caliciviridae; Norovirus; Norovirus norwalkense.
REFERENCE 1 (bases 1 to 7477)
AUTHORS Barclay,L., Cannon,J.L., Wikswo,M.E., Phillips,A., Browne,H.,
Montmayeur,A.M., Tatusov,R.L., Burke,R.M., Hall,A.J. and Vinje,J.
TITLE Emergence and characterization of multiple viruses associated with
a novel GII.P16 polymerase in the United States, 2015-2018
JOURNAL Unpublished
REFERENCE 2 (bases 1 to 7477)
AUTHORS Barclay,L., Cannon,J.L., Johnston,J., Montmayeur,A.M.,
Tatusov,R.L., Chhabra,P. and Vinje,J.
TITLE Direct Submission
JOURNAL Submitted (05-APR-2019) Division of Viral Diseases, Centers for
Disease Control and Prevention, 1600 Clifton Road NE, Atlanta, GA
30329, USA
COMMENT ##Assembly-Data-START##
Assembly Method :: Geneious v. R10; SPAdes v. 3.6
Sequencing Technology :: Illumina
##Assembly-Data-END##
FEATURES Location/Qualifiers
source 1..7477
/organism="Norovirus GII"
/mol_type="genomic RNA"
/strain="Baltimore0201"
/isolate="Hu/US/2017/GII.P16-GII.4 Sydney/Baltimore0201"
/isolation_source="stool"
/host="Homo sapiens"
/db_xref="taxon:122929"
/geo_loc_name="USA"
/collection_date="30-Nov-2017"
/note="genotype: GII.P16-GII.4 Sydney"
gene 2..5101
/gene="ORF1"
CDS 2..5101
/gene="ORF1"
/codon_start=1
/product="nonstructural polyprotein"
/protein_id="QBW96033.1"
/translation="MKMASNDATVAVACNNNNDKEKSSGEGIFTNMSSTLKKALGARP
KQPAPRDKPQKPPRPPTPELVKRIPPPPPNGEEEEEPVIRYEVKSGISGLPELTTVPQ
PDVANTAFSVPPLSLRENREAKEPLTGAILEMWDGEIYHYGLYVEKGLVLGVHKPPAA
ISMARVELTPLSLYWRVVYTPQYLISPETLRRLNGEAFPYTAFDNNCYAFCCWVLDLN
DSWLSRRMVQRTTGFFRPYQEWNRKPLPTMDDSKIKKVANIFLCSLSTLFTRPIKDLI
GKIKPLNILNILATCDWTFAGIVESLILLAELFGVFWTPPDVSAMIAPLLGDYELQGP
EDLAVELVPVVMGGVGLVLGFTKEKIGKMLSSAASTLRACKDLGAYGLEILKLIMKWF
FPKKEEANELAMVRAIEDAVLDLEAIENNHMTTLLKDKDSLATYMKTLDMEEEKARRL
STKSASPDIVGTINALLARIAAARSLVHRAKEELSSRIRPVVVMISGKPGIGKTHLAR
EVARKVASTLTGDQRVGLIPRNGVDHWDAYKGERVVLWDDYGMSNPIHDALRIQELAD
TCPLTLNCDRIENKGKVFDSEVIIITTNLANPAPLDYVNFEACSRRIDFLVYAEAPEV
EKAKRDFPGQPDMWKDAFKPDFSHIKLQLAPQGGFDKNGNTPHGKGVMKTLTTGSLIA
RASGLLHERMDEFELQGPTITTFNFDRNRITAFRQLAAENKYGLVDTMKVGNQLKGVK
TMEELKQAIRNVTIKRCRIIYGGSTYDLESDGKGKVLVEKVENTSVQTNNELAGALHH
LKHARIRYYVKCVQEAVYSIIQIAGAAFVTTRIARRMNIQELWSKPQLDQNESEAKEE
APKSEDDEFIISSKDIKEEGKKGKNKTGRGKKHTAFSSKGLSDEEYDEYKRIREERNG
KYSIEEYLQDRDRYYEELAIAKATEEDFCEEEEIKIRQRIFRPTRKQRKEERATLGLV
TGSEIRKRNPDDFKPKGKLWADDNRSVDYNEKLDFEAPPSIWSRIVSFGSGWGFWVSP
SLFITSTHVIPAGVTEAFGVPIKQIQIHKSGEFCRFRFPKPIRPDVTGMILEEGAPEG
TVATVLIKRPTGELMPLAARMGTHATMKIQGRMVGGQMGMLLTGSNAKGMDLGTTPGD
CGCPYIYKRGNDYIVIGVHTAAARGGNTVICATQGSEGEATLEGGDDKGTYCGAPILG
PGGAPKLSTKTKFWRSSNTPLPPGTYEPAYLGGRDPRVKGGPSLQQVMRDQLKPFTEP
RGKPPRPSVLEAAKQTIINVLEQTLDPPQKWTYAQACASLDKTTSSGHPHHVRKNEFW
NGETFTGKLADQASKANLMFEEGKHMTPVYTAALKDELVKTEKIYGKIKKRLLWGSDL
STMIRCARSFGGLMDEMKAHCISLPVRVGMNMNEDGPIIFEKHSRYKYHYDADYSRWD
STQQRAVLAAALEIMVRFSAEPQLAQIVAEDLLAPSVVDVGDFKITINEGLPSGVPCT
SQWNSIAHWLLTLCALSEVTKLSPDIIQANSMFSFYGDDEIVSTDIKLNPEQLTAKLK
EYGLKPTRPDKTEGPLIISEDLNGLTFLRRTVTRDPAGWFGKLDQSSILRQMYWTRGP
NHEDPNETMIPHSQRPIQLMALLGEASLHGPSFYSRISKLVITELKEGGMDFYVPRQE
PMFRWMRFSDLSTWEGDRNLAPNFVNEDGVE"
mat_peptide 2..997
/gene="ORF1"
/product="p48"
mat_peptide 998..2095
/gene="ORF1"
/product="NTPase"
mat_peptide 2096..2626
/gene="ORF1"
/product="p22"
mat_peptide 2627..3025
/gene="ORF1"
/product="VPg"
mat_peptide 3026..3568
/gene="ORF1"
/product="Pro"
mat_peptide 3569..5098
/gene="ORF1"
/product="RdRp"
gene 5082..6704
/gene="ORF2"
CDS 5082..6704
/gene="ORF2"
/note="major capsid protein"
/codon_start=1
/product="VP1"
/protein_id="QBW96034.1"
/translation="MKMASSDANPSDGSAANLVPEVNNEVMALEPVVGAAIAAPVAGQ
QNVIDPWIRNNFVQAPGGEFTVSPRNAPGEILWSAPLGPDLNPYLSHLARMYNGYAGG
FEVQVILAGNAFTAGKIIFAAVPPNFPTEGLSPSQVTMFPHIIVDVRQLEPVLIPLPD
VRNNFYHYNQSNDSTIKLIAMLYTPLRANNAGDDVFTVSCRVLTRPSPDFDFIFLVPP
TVESRTKPFSVPVLTVEEMTNSRFPIPLEKLFTGPSSAFVVQPQNGRCTTDGVLLGTT
QLSPVNICTFRGDVTHITGSHNYTMNLASQNWNNYDPTEEIPAPLGTPDFVGKIQGML
TQTTRTDGSTRGHKATVYTGSADFAPKLGRVQFETDTNHDFEANQNTKFTPVGVIQDG
STTHRNEPQQWVLPSYSGRNTHNVHLAPAVAPTFPGEQLLFFRSTMPGCSGYPNMDLD
CLLPQEWVQYFYQEAAPAQSDVALLRFVNPDTGRVLFECKLHKSGYVTVAHTGQHDLV
IPPNGYFRFDSWVNQFYTLAPMGNGTGRRRVV"
gene 6704..>7477
/gene="ORF3"
CDS 6704..>7477
/gene="ORF3"
/note="minor structural protein; small basic protein"
/codon_start=1
/product="VP2"
/protein_id="QBW96035.1"
/translation="MAGAFFAGLASDVLGSGLGSLINAGAGAINQKVEFENNRKLQQA
SFQFSSNLQQASFQHDKEMLQEQIEATKKLQQEMMKVKQAMLLEGGFSETDAARGAIN
APMTKALDWSGTRYWAPDARITTYNAGHFSTPQPSRALPGRANLGDAVPARGPSNKSS
NSSTATSVHSSQTISTRLGSTAGSGTSVSSLPSTARTRSWVEDQNRNLSPFMRGAHNI
SFVTPPSSRSSSQGTVSTVPKEILDSWTGAFNTRRQPLLA"
ORIGIN
1 aatgaagatg gcgtctaacg acgctaccgt tgccgttgct tgcaacaaca acaacgacaa
61 ggaaaaatct tcaggtgaag gcatattcac aaatatgtct tccaccttaa agaaagccct
121 cggggctagg cccaaacagc ctgccccgag agacaaacca caaaaacccc caagaccacc
181 aactcccgag ttggtcaaga ggataccccc tcctccacct aatggcgaag aagaggaaga
241 accagtcatt aggtatgagg ttaagagtgg gatctctggc ctgcccgagc tcacaacagt
301 ccctcaaccg gacgtggcca acacagcatt cagtgttcca ccactgagct tgagagaaaa
361 cagggaggcc aaggaaccgc taacaggggc aatattagag atgtgggacg gagagatata
421 ccactatggc ttgtacgtgg agaaaggctt agtgttgggt gtgcacaaac cacctgcagc
481 cataagcatg gctagagtgg agctgacgcc gctgtcattg tactggcgtg tggtgtacac
541 tccccaatac ctcatctccc ctgaaactct caggaggctc aacggagagg cgttccctta
601 caccgccttc gacaacaact gctatgcctt ttgctgctgg gtgttagacc tcaatgactc
661 atggcttagc aggaggatgg tgcaaagaac aacgggcttc ttcagacctt accaagagtg
721 gaacagaaaa cccctgccca ccatggatga ctccaaaata aagaaggtag caaatatatt
781 cctgtgttca ttgtccacat tattcaccag acccataaaa gacctcatag gaaaaattaa
841 accattaaac atattgaaca tcctggcaac gtgtgactgg acgtttgccg gaatagtgga
901 gtctctgata ttacttgctg aactcttcgg agttttctgg acacccccag atgtgtctgc
961 tatgatcgct cccttactcg gggactacga gttgcaaggg ccagaagacc tcgccgttga
1021 actcgtacct gtggtaatgg gaggggttgg tttggtgttg ggattcacca aagagaaaat
1081 tggcaaaatg ttgtcctcag cagcatcaac actcagggct tgcaaagatc ttggtgccta
1141 tggcttagag atactcaaac tgatcatgaa gtggttcttc ccaaagaaag aggaggccaa
1201 tgagctagcc atggtgagag ccatagagga tgccgtacta gatcttgagg caatagaaaa
1261 taaccacatg acaaccctgt tgaaagacaa agacagctta gcaacataca tgaaaacact
1321 ggacatggag gaggagaaag ccagaaggtt gtccacaaaa tctgcatccc ctgacatagt
1381 tgggacaatc aacgccctgc tggctcgaat agcagcagcc aggtcattag tccacagggc
1441 caaggaagag ctatctagta ggataagacc agtagttgtt atgatatctg gcaaaccagg
1501 aataggcaaa actcatctgg ccagggaggt ggcaagaaag gtggcatcca ctctcacagg
1561 ggatcaaaga gtcggactca taccaagaaa cggtgtggac cattgggatg catacaaagg
1621 tgagagagtc gtgctgtggg acgactatgg catgagtaac cccattcatg atgctcttcg
1681 catacaagaa ttggctgata cgtgccccct taccttaaat tgtgacagaa ttgaaaataa
1741 ggggaaagtt tttgacagtg aagtcataat aattacaaca aaccttgcca acccagcccc
1801 acttgattat gtcaactttg aggcctgttc caggagaatc gatttcctgg tgtacgctga
1861 ggcaccagaa gtagaaaagg caaaacggga ttttcctggt cagccagata tgtggaagga
1921 cgccttcaag ccggactttt cacacatcaa gctacagctt gcacctcagg gcggctttga
1981 caagaatggc aacaccccac atgggaaagg ggtgatgaag accctcacta ccggttctct
2041 gattgcccgt gcatcaggcc tactgcatga gaggatggat gaatttgaac tccaaggtcc
2101 cacaatcacc acctttaatt tcgaccggaa tagaatcaca gcattcagac aattggctgc
2161 agaaaacaag tatggattgg tggacaccat gaaagttggc aatcaactaa aaggagtgaa
2221 aaccatggaa gaactcaaac aagcaatcag gaatgtgacc atcaagaggt gccggatcat
2281 ctacggtggc tccacgtatg accttgaatc tgatggcaag ggcaaagttt tggtggaaaa
2341 ggtcgagaac acctctgtac agaccaacaa cgagttggcc ggggccctgc accacctcaa
2401 acacgcccga atcaggtact atgtcaaatg tgtgcaagaa gcagtctatt ccatcataca
2461 aattgccggc gctgcgtttg tcaccacgcg cattgcacgc cgcatgaaca tacaagaact
2521 ctggtcgaag ccacaattag atcaaaatga atcagaggct aaggaagagg cccccaagtc
2581 agaagatgac gagttcatca tatcttctaa ggacatcaag gaggaaggaa agaagggcaa
2641 gaacaaaact ggccgtggca agaaacacac tgcattctcc agcaagggct tgagcgatga
2701 ggagtatgac gagtacaaga ggataagaga agagagaaat gggaagtact ctatagagga
2761 gtatcttcaa gacagagaca ggtactatga ggagctcgcc attgccaagg ccacggaaga
2821 agacttctgt gaagaggagg agatcaaaat ccgtcagaga attttccgtc ccaccaggaa
2881 acaaagaaag gaagagaggg ccacattagg gctggtaaca ggttcagaaa tcagaaaaag
2941 aaaccctgat gacttcaaac ccaaagggaa gctgtgggcc gatgacaaca gaagtgttga
3001 ctacaatgag aaactggatt ttgaggcccc cccaagcata tggtctagga ttgtgagctt
3061 tggttctggc tggggcttct gggtatcacc aagtctgttc ataacatcaa ctcatgtaat
3121 ccccgcaggt gtaacagaag catttggagt ccccatcaaa caaattcaga tccacaaatc
3181 aggtgaattt tgccgattca gattcccaaa accgattaga ccagatgtga caggaatgat
3241 cttggaagaa ggtgcgcctg aaggcaccgt ggcaactgtg ctcatcaaac gccccaccgg
3301 agagctcatg cctcttgcag ccagaatggg aacacacgca accatgaaaa ttcaaggccg
3361 catggttggc ggacagatgg gtatgttgct cactggatca aatgctaaag gaatggattt
3421 gggaacaact cctggtgact gtggctgtcc ttacatctat aaaaggggca atgactatat
3481 agtcattggg gtgcacactg cagcagcccg tggtggaaac accgtcatct gtgccacaca
3541 gggaagtgag ggtgaggcaa ctcttgaggg tggagatgac aaaggaacat actgtggggc
3601 acccatttta ggccctgggg gtgcaccaaa attgagcacc aaaaccaaat tttggaggtc
3661 atcgaacacg ccccttccac cagggacata tgaacctgcc tacctcggtg gccgtgatcc
3721 gcgtgttaag ggtgggccct ccttgcagca ggtaatgaga gaccagttga agccattcac
3781 tgaacccagg ggaaaacctc caagaccaag tgtattggaa gcagccaaac aaaccatcat
3841 caatgttctc gaacaaaccc tggaccctcc acaaaaatgg acatacgcac aggcgtgtgc
3901 ctcacttgac aaaaccacct ccagcgggca tccccatcac gtccgaaaga atgaattctg
3961 gaatggtgag accttcactg gtaaattggc agaccaagca tcaaaagcaa acctaatgtt
4021 tgaggaaggg aaacacatga caccagtgta tacagcagca ctcaaggacg agctagtcaa
4081 gactgagaaa atctatggaa agatcaagaa gagactgctc tggggctctg acttgtccac
4141 catgatccgg tgcgctaggt catttggtgg gctcatggac gagatgaagg cacactgcat
4201 atcactccca gtacgagttg gcatgaatat gaatgaagat ggcccaataa tatttgagaa
4261 acattccaga tataaatacc actatgacgc agactactct cgttgggatt caacacaaca
4321 gagggcagta ctagcagcag ccttggaaat catggtcaga ttctctgcag aaccacaatt
4381 ggcacaaata gtcgctgagg atctactggc tcctagtgta gtagatgtag gagactttaa
4441 aatcacaata aatgaagggc ttccatctgg tgtgccatgc acttctcaat ggaactccat
4501 cgcacactgg ctgctaactc tctgtgcctt gtctgaagtc accaaactgt cccctgacat
4561 tatacaagca aattccatgt tctcttttta cggtgatgac gagattgtca gcaccgacat
4621 aaaattgaac cccgaacagt taaccgccaa gttgaaggag tacggcctga aaccaacccg
4681 cccagacaag accgagggac ccctgatcat cagtgaagat ttgaacggac tcactttcct
4741 ccgaaggacg gtgactcgtg acccagctgg ctggtttgga aaactggacc aaagttcaat
4801 tttaaggcag atgtactgga ctagaggacc aaatcatgaa gaccccaatg agacaatgat
4861 accccattct caaagaccca tacagctcat ggcattgctt ggtgaagcct ctcttcacgg
4921 accctctttc tacagtagaa tcagtaaatt ggtcataact gaactcaaag aaggtgggat
4981 ggacttttac gtgccaaggc aggaaccgat gttcaggtgg atgaggtttt ctgacttgag
5041 cacgtgggag ggcgatcgca atctggctcc caattttgtg aatgaagatg gcgtcgagtg
5101 acgccaaccc atctgatggg tccgcagcca acctcgtgcc agaggtcaac aatgaggtta
5161 tggctttgga gcccgttgtt ggtgccgcta ttgcggcacc tgtagcgggc caacaaaatg
5221 taattgaccc ctggattaga aataattttg tacaagcccc tggtggggag tttacagtgt
5281 cccctagaaa cgctccaggt gaaatactat ggagcgcgcc cctaggccct gacctaaatc
5341 cctacctatc ccatttggcc agaatgtaca atggttatgc aggtggtttt gaagtgcagg
5401 taattctcgc ggggaacgcg ttcaccgccg ggaagattat atttgcagca gtcccaccaa
5461 attttccaac tgaaggctta agtcccagcc aggttactat gttcccccat ataatagtag
5521 atgttagaca attagaacct gtgttgattc ccttacccga tgttaggaat aatttctatc
5581 attataacca gtcaaatgat tccactatta agttgatagc aatgttgtat acaccactta
5641 gggctaataa tgctggagat gatgttttca cagtttcgtg ccgagtgctc acgagaccat
5701 cccccgattt tgatttcata tttttagtgc cacccacagt tgagtcaaga actaaaccat
5761 tctctgtccc agttttaact gttgaggaga tgaccaattc aagattcccc atccctttgg
5821 aaaagttgtt cacaggccct agcagtgcct ttgttgttca accacaaaat ggcaggtgca
5881 caactgatgg cgtgctccta ggcaccaccc aactttctcc tgtcaacatc tgcaccttca
5941 gaggggatgt cacccacatc acaggtagtc acaactacac aatgaatttg gcttctcaaa
6001 attggaacaa ctatgaccca acagaagaaa tcccagcccc tctaggaact ccagattttg
6061 tggggaagat tcaaggcatg ctcacccaaa ccacaaggac agatggttca acacgcggcc
6121 acaaagctac agtgtacact gggagcgccg actttgctcc aaaactgggt agagttcaat
6181 ttgaaactga cacaaaccat gattttgaag ctaatcaaaa cacaaagttc accccagtcg
6241 gtgtcatcca agatggtagc accactcacc gaaacgaacc ccaacagtgg gtgctcccaa
6301 gttactcagg cagaaatact cacaatgtac atttggcccc cgctgtagcc cccacctttc
6361 cgggtgagca acttctcttc ttcagatcca ccatgcccgg atgcagcggg taccccaaca
6421 tggatttgga ctgtctgctt ccccaggaat gggtgcagta cttttaccaa gaggcagccc
6481 cagcacaatc tgacgtggct ctgctaagat ttgtgaatcc agacacaggt agggttttat
6541 ttgagtgcaa gcttcacaaa tcaggctatg ttacagtggc tcacactggc caacatgact
6601 tggttatccc ccccaatggt tactttaggt ttgattcctg ggtcaaccag ttctacacgc
6661 ttgcccccat gggaaatgga acggggcgta gacgtgtagt ataatggctg gagctttctt
6721 tgctggattg gcatctgatg tccttggctc tggacttggt tcccttatca atgctggggc
6781 tggggccatc aaccaaaaag ttgaatttga aaataacaga aaattgcaac aagcatcctt
6841 ccaatttagc agtaatctgc aacaggcttc ctttcaacat gacaaagaga tgctccaaga
6901 acaaattgag gccaccaaaa agctacaaca ggaaatgatg aaagttaagc aggcaatgct
6961 cctagagggt gggttctctg agacagatgc agcccgcggg gcaattaacg cccctatgac
7021 aaaggctttg gactggagcg gaacaaggta ctgggctcca gatgctagga ttacaacata
7081 caatgcaggc cacttttcca cccctcagcc atcgagggca ctgccaggaa gagctaatct
7141 tggggatgct gttcctgctc ggggaccctc caacaaatct tctaactctt ctactgctac
7201 ctctgtgcac tcaagtcaaa ctatttcaac gagacttggt tctacagctg gttctggaac
7261 cagtgtctcg agcctcccgt caactgcaag gactaggagc tgggttgagg atcaaaatag
7321 aaatttgtca cctttcatga ggggggccca caatatatca tttgtcaccc caccatctag
7381 cagatcctct agccaaggca cagtctcaac cgtgcctaaa gagattttgg actcctggac
7441 tggcgctttc aacacgcgca ggcagcctct cttagct
//