Typing tool
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Typing tool
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Complete norovirus genomes
| MK753036 | GII.12 | |
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| GII.P16 |
ORF1: 5..5104
ORF2: 5085..6692
ORF3: 6692..7471
LOCUS MK753036 7480 bp RNA linear VRL 11-APR-2019
DEFINITION Norovirus GII isolate Hu/US/2017/GII.P16-GII.12/SanDiego0142
nonstructural polyprotein (ORF1), VP1 (ORF2), and VP2 (ORF3) genes,
complete cds.
ACCESSION MK753036
VERSION MK753036.1
KEYWORDS .
SOURCE Norovirus GII
ORGANISM Norovirus GII
Viruses; Riboviria; Orthornavirae; Pisuviricota; Pisoniviricetes;
Picornavirales; Caliciviridae; Norovirus; Norwalk virus.
REFERENCE 1 (bases 1 to 7480)
AUTHORS Barclay,L., Cannon,J.L., Wikswo,M.E., Phillips,A., Browne,H.,
Montmayeur,A.M., Tatusov,R.L., Burke,R.M., Hall,A.J. and Vinje,J.
TITLE Emergence and characterization of multiple viruses associated with
a novel GII.P16 polymerase in the United States, 2015-2018
JOURNAL Unpublished
REFERENCE 2 (bases 1 to 7480)
AUTHORS Barclay,L., Cannon,J.L., Pan,C.-Y., Montmayeur,A.M., Tatusov,R.L.,
Chhabra,P. and Vinje,J.
TITLE Direct Submission
JOURNAL Submitted (05-APR-2019) Division of Viral Diseases, Centers for
Disease Control and Prevention, 1600 Clifton Road NE, Atlanta, GA
30329, USA
COMMENT ##Assembly-Data-START##
Assembly Method :: Geneious v. R10; SPAdes v. 3.6
Sequencing Technology :: Illumina
##Assembly-Data-END##
FEATURES Location/Qualifiers
source 1..7480
/organism="Norovirus GII"
/mol_type="genomic RNA"
/strain="SanDiego0142"
/isolate="Hu/US/2017/GII.P16-GII.12/SanDiego0142"
/isolation_source="stool"
/host="Homo sapiens"
/db_xref="taxon:122929"
/country="USA"
/collection_date="02-Dec-2017"
/note="genotype: GII.P16-GII.12"
gene 5..5104
/gene="ORF1"
CDS 5..5104
/gene="ORF1"
/codon_start=1
/product="nonstructural polyprotein"
/protein_id="QBS54678.1"
/translation="MKMASNDATVAVACNNNNDKEKSSGEGLFTNMSSTLKKALGARP
KQPAPRDKPQKPPRPPTPELVKRIPPPPPNGEEEEEPVIRYEVKSGISGLPELTTVPQ
PDVANTAFSVPPLSLRENREAKEPLTGAILEMWDGEIYHYGLYVEKGLVLGVHKPPAA
ISMAKVELTPLSLYWRVVYTPQYLISPETLRRLNGEAFPYTAFDNNCYAFCCWVLDLN
DSWLSRRMVQRTTGFFRPYQEWNRKPLPTMDDSKIKKVANIFLCSLSTLFTRPIKDLI
GKIKPLNILNILATCDWTFAGIVESLILLAELFGVFWTPPDVSAMIAPLLGDYELQGP
EDLAVELVPVVMGGIGLVLGFTKEKIGKMLSSAASTLRACKDLGAYGLEILKLVMKWF
FPKKEEANELAMVRAIEDAVLDLEAIENNHMTTLLKDKDSLATYMKTLDMEEEKARRL
STKSASPDIVGTINALLARIAAARSLVHRAKEELSSRMRPVVVMISGKPGIGKTHLAR
EVARKVASTLTGDQRVGLIPRNGVDHWDAYKGERVVLWDDYGMSNPIHDALRIQELAD
TCPLTLNCDRIENKGKVFDSEVIIITTNLANPAPLDYVNFEACSRRIDFLVYAEAPDV
EKAKRDFPGQPDMWKDAFKSDFSHIKLQLAPQGGFDKNGNTPHGKGVMKTLTTGSLIA
RASGLLHERMDEFELQGPTITTFNFDRNRITAFRQLAAENKYGLVDTMKVGNQLKGVK
TMEELKQAIRNVTIKRCRIIYGGSTYDLESDGKGKVLVEKVKNASVQTNNELAGALHH
LKHARIRYYVKCVQEAVYSIIQIAGAAFVTTRIARRMNIQELWSKPQLDQNESETKEE
APKPEDDEFVISSKDIKEEGKKGKNKTGRGKKHTAFSSKGLSDEEYDEYKRIREERNG
KYSIEEYLQDRDRYYEELAIAKATEEDFCEEEEIKIRQRIFRPTRKQRKEERATLGLV
TGSEIRKRNPDDFKPKGKLWADDNRSVDYNEKLDFEAPPSIWSRIVSFGSGWGFWVSP
SLFITSTHVIPTGITEAFGVPIKQVQIHKSGEFCRFRFPKPIRPDVTGMILEEGAPEG
TVATVLIKRPTGELMPLAARMGTHATMKIQGRMVGGQMGMLLTGSNAKGMDLGTTPGD
CGCPYIYKRGNDYIVIGVHTAAARGGNTVICATQGSEGEATLEGGDDKGTYCGAPILG
PGGAPKLSTKTKFWRSSNTPLPPGTYEPAYLGGRDPRVKGGPSLQQVMRDQLKPFTEP
RGKPPRPSVLEAAKQTIINVLEQTLDPPQKWTYAQACASLDKTTSSGHPYHVRKNEFW
NGETFTGKLADQASKANLMFEEGKHMTPVYTAALKDELVKTEKIYGKIKKRLLWGSDL
STMIRCARSFGGLMDEMKAHCISLPVRVGMNMNEDGPIIFEKHSRYKYHYDADYSRWD
STQQRAVLAAALEIMVRFSAEPQLAQIVAEDLLAPSVVDVGDFKITINEGLPSGVPCT
SQWNSIAHWLLTLCALSEVTKLSPDIIQANSMFSFYGDDEIVSTDIKLDPEQLTAKLK
EYGLKPTRPDKTEGPLIISEDLNGLTFLRRTVTRDPAGWFGKLDQSSILRQMYWTRGP
NHEDPNETMIPHSQRPIQLMALLGEASLHGPSFYSKISKLVITELKEGGMDFYVPRQE
PMFRWMRFSDLSTWEGDRNLAPNFVNEDGVE"
mat_peptide 5..1000
/gene="ORF1"
/product="p48"
mat_peptide 1001..2098
/gene="ORF1"
/product="NTPase"
mat_peptide 2099..2629
/gene="ORF1"
/product="p22"
mat_peptide 2630..3028
/gene="ORF1"
/product="VPg"
mat_peptide 3029..3571
/gene="ORF1"
/product="Pro"
mat_peptide 3572..5101
/gene="ORF1"
/product="RdRp"
gene 5085..6692
/gene="ORF2"
CDS 5085..6692
/gene="ORF2"
/note="major capsid protein"
/codon_start=1
/product="VP1"
/protein_id="QBS54679.1"
/translation="MKMASNDAAPSNDGAAGLVPEVNNETMALEPVAGASIAAPLTGQ
NNVIDPWIRLNFVQAPNGEFTVSPRNSPGEVLLNLELGPELNPYLAHLSRMYNGYAGG
VEVQVLLAGNAFTAGKLVFAAVPPHFPLENISPGQITMFPHVIIDVRTLEPVLLPLPD
VRNNFFHYNQQNEPRMRLVAMLYTPLRSNGSGDDVFTVSCRVLTRPSPDFDFNYLVPP
TVESKTKPFTLPVLTIGELTNSRFPVPIDELYTSPNESLVVQPQNGRCALDGELQGTT
QLLPTAICSFRGRINQKVSGENHVWNMQVTNINGTPFDPTEDVPAPLGTPDFSGKLFG
VLSQRDHDNACRSHDAVIATHSTKFTPKLGAVQIGTWEQDDVHINQPTKFTPVGLFEN
EGFNQWTLPNYSGALTLNMGLAPPVAPTFPGEQILFFRSHIPLKGGVADPVIDCLLPQ
EWIQHLYQESAPSQTDVALIRFTNPDTGRVLFEAKLHRSGYITVANTGSRPIVVPANG
YFRFDSWVNQFYSLAPMGTGNGRRRMQ"
gene 6692..7471
/gene="ORF3"
CDS 6692..7471
/gene="ORF3"
/note="minor structural protein; small basic protein"
/codon_start=1
/product="VP2"
/protein_id="QBS54680.1"
/translation="MAGAFIAGLAGDIVTNSIGSLVNAGANAINQKVDFENNKQLQQA
SFNHDKEMLQAQIQATKQLQADMIAIRQGVLTAGGFSPTDAARGAVNAPMTQVLDWNG
TRHWAPGATKTTAFSGGFTSASHARTVDLTKKTSATPAPMPVSRPSSNASTVSTRSTL
ISGSSNSPASARSSSSVSSQPTSSSSRTSEWVRSQNRALEPYMNGALRTAYVTPPSSR
ASSNGTVSTVPKEVLDSWSSAFNTHRQPLFAHLRRRGESQA"
ORIGIN
1 gtgaatgaag atggcgtcta acgacgctac cgttgccgtt gcttgcaaca acaacaacga
61 caaggaaaaa tcttcaggtg aaggcttatt cacaaatatg tcttctacct taaagaaagc
121 cctcggggct aggcccaaac agcctgcccc gagagacaaa ccacaaaagc ccccaagacc
181 accaactcca gagttggtca agaggatacc ccctcctcca cctaatggcg aagaagaaga
241 agaaccagtc attaggtatg aggttaagag tgggatctct ggcctgcccg agctcacaac
301 agtcccccaa ccggacgtgg ccaacacagc attcagtgtt ccaccactga gcttgagaga
361 aaacagggaa gccaaggaac cgctaacagg ggcaatatta gagatgtggg atggagagat
421 ataccactac ggcctgtacg tggagaaagg cttagtgttg ggtgtacaca aaccacctgc
481 agccataagc atggcaaaag tggagctgac gccgctgtca ttgtattggc gtgtggtgta
541 cactccccaa tacctcatct cccctgaaac tctcaggagg ctcaacggag aggcattccc
601 ttacaccgct tttgacaaca actgctatgc cttttgctgc tgggtattag acctcaatga
661 ctcatggctt agcaggagga tggtgcaaag aacaacgggc ttcttcagac cttaccaaga
721 gtggaacaga aaacccctgc ctaccatgga tgactccaaa attaagaagg tagcaaatat
781 attcctatgt tcattgtcca cattgttcac tagacccata aaagacctca taggaaaaat
841 taaaccatta aacatattga atatcctggc aacgtgtgac tggacgtttg ccggaatagt
901 ggagtctcta atattacttg ctgaactctt cggagttttc tggacacccc cagatgtgtc
961 tgctatgatc gctcccttac ttggggatta cgagttgcaa gggccagaag acctcgccgt
1021 tgaactcgta cctgtggtga tgggagggat tggtttggtg ttgggattca ccaaagagaa
1081 aattggcaaa atgttgtcct cagcagcatc aacactcagg gcttgcaaag accttggtgc
1141 ctatggctta gagatactca aattggtcat gaaatggttc ttcccaaaga aagaggaggc
1201 caatgagcta gccatggtga gggccataga ggacgctgta ctagatcttg aggcaataga
1261 aaataaccac atgacaaccc tgttgaaaga caaagacagc ttagcaacat acatgaaaac
1321 actggacatg gaggaggaga aagccagaag gttgtccaca aaatctgcat cccctgacat
1381 agttgggaca atcaacgccc tgctggctcg aatagcagcg gccaggtcat tagttcacag
1441 ggccaaggaa gagctatcta gcaggatgag accagtagtt gttatgatat ctggcaaacc
1501 aggaataggc aaaactcatc tggccaggga agtggcaaga aaggtggcat ccactctcac
1561 aggggatcaa agagtcggac tcataccaag aaacggtgtg gaccattggg atgcatacaa
1621 aggtgagaga gtcgtgctgt gggacgacta tggcatgagt aaccccattc atgatgctct
1681 tcgcatacaa gaattggctg acacgtgtcc cctcacctta aattgtgaca gaattgaaaa
1741 taaaggaaaa gtttttgaca gtgaagtcat aataatcaca acaaaccttg ccaatccagc
1801 cccgcttgat tatgtcaact ttgaggcctg ttccaggaga attgatttcc tggtgtacgc
1861 tgaggcacca gatgtggaaa aggcaaaacg ggacttccct ggtcagccag atatgtggaa
1921 ggacgccttc aaatcggact tttcacacat caagctacag cttgcacctc agggcggctt
1981 tgacaaaaac ggcaacaccc cacatgggaa aggggtgatg aagaccctca ctaccggttc
2041 tctgattgcc cgcgcatcag gcctactgca tgagaggatg gatgaatttg aactccaagg
2101 tcctacaatc accaccttca atttcgaccg gaacagaatc acagcattca gacaattggc
2161 tgcagaaaac aagtatggac tggtggacac catgaaagtc ggcaatcaat taaaaggagt
2221 gaaaaccatg gaagagctca aacaagcaat caggaatgtg accatcaaga ggtgccggat
2281 catctacggt ggctccacat atgaccttga atctgatggc aagggcaaag ttttggtgga
2341 aaaggtcaag aacgcctctg tacagaccaa caatgagttg gccggggccc tgcaccatct
2401 caaacacgcc cgaatcaggt actatgtcaa gtgtgtgcaa gaagcagtct attctatcat
2461 acaaattgcc ggcgctgcgt ttgtcaccac gcgcattgca cgccgcatga atatacaaga
2521 actctggtcg aagccacaat tggatcaaaa tgaatcagag actaaggaag aggcccccaa
2581 gccagaagat gacgagttcg tcatatcttc taaggacatc aaggaggaag gaaagaaggg
2641 caaaaataaa actggccgtg gcaagaaaca cactgcattc tccagcaagg gcttgagcga
2701 tgaggagtat gacgagtaca agaggataag agaagagaga aatgggaagt actctataga
2761 ggaatatctt caagacagag acaggtacta tgaagaactc gccattgcca aggccacgga
2821 agaagacttc tgtgaagagg aggagataaa aatccgtcag agaattttcc gtcctaccag
2881 gaaacaaagg aaggaagaga gggccacatt agggctagta acaggttcag aaatcagaaa
2941 aagaaaccct gatgacttca aacccaaagg gaagttgtgg gccgatgaca acagaagtgt
3001 tgactacaat gagaaactgg attttgaggc ccccccaagc atatggtcta ggattgtgag
3061 ttttggttct ggctggggct tctgggtatc accaagcctg ttcataacat caactcatgt
3121 aatccccaca ggcataacag aagcatttgg agtccccatc aaacaagttc aaatccacaa
3181 atcaggtgaa ttttgccgat tcagattccc aaaaccaatt agaccagatg tgacaggaat
3241 gatcttggaa gaaggtgcgc ctgagggcac cgtggcaact gtgctcatca aacgccccac
3301 cggagagctc atgcctcttg cagccagaat gggaacacac gcaaccatga aaattcaagg
3361 ccgcatggtt ggcggacaga tgggcatgtt gctcactgga tcaaatgcta aaggaatgga
3421 tttgggaaca actcctggag actgtggctg tccttacatc tataaaaggg gcaatgacta
3481 tatagtcatt ggggtgcaca ctgcagcagc ccgtggtgga aacaccgtca tctgtgccac
3541 acagggaagt gagggtgagg caactcttga gggtggagat gacaaaggaa catactgtgg
3601 ggcacccatc ctaggccctg ggggtgcacc aaaattgagc accaaaacca aattttggag
3661 gtcatcgaac acgccccttc caccagggac atatgagcct gcctacctcg gcggccgtga
3721 cccgcgtgtt aagggtgggc cctccttgca gcaggtaatg agagaccagt tgaagccatt
3781 cactgaaccc aggggcaaac ctccaagacc aagtgtgttg gaagcagcca aacaaaccat
3841 catcaatgtc cttgagcaaa ccctggaccc tccacaaaaa tggacatacg cacaggcgtg
3901 tgcctcactt gacaaaacca catccagcgg tcacccctat cacgttcgaa agaatgaatt
3961 ctggaatggt gagaccttca ctggtaaatt ggcagaccaa gcatcaaaag caaacctaat
4021 gtttgaggaa gggaagcaca tgacaccagt gtatacagca gcactcaagg acgagctagt
4081 caagactgag aaaatctatg gaaagatcaa gaagagactg ctctggggct ctgacttgtc
4141 caccatgatc cggtgcgcta ggtcatttgg tgggctcatg gacgagatga aggcacactg
4201 catatcactc ccagtccgag ttggcatgaa tatgaatgaa gatggcccaa taatatttga
4261 gaaacattcc agatacaaat atcactatga tgcagactac tctcgttggg attcaacaca
4321 acagagggca gtactggcag cagccttgga aatcatggtc agattctctg cagaaccaca
4381 attggcacaa atagtcgctg aggatctact ggcccctagt gtagtagatg taggagactt
4441 taaaatcaca ataaatgagg ggctcccctc tggtgtgcca tgcacttctc aatggaactc
4501 catcgcacac tggctgctaa ctctctgtgc cttgtctgaa gtcactaagc tgtcacctga
4561 cattatacag gcaaattcca tgttctcatt ttacggtgat gacgagattg tcagcaccga
4621 cataaaattg gaccccgaac agttaaccgc caaattgaag gagtacggcc taaaaccaac
4681 ccgcccagac aaaaccgagg gacccctgat catcagtgaa gatttgaacg gactcacttt
4741 cctccgaaga acggtgactc gtgacccagc tggctggttt ggaaaactgg accaaagctc
4801 aattttgagg cagatgtact ggactagagg accaaatcat gaagacccca atgagacaat
4861 gataccccat tctcaaaggc ccatacagct catggcactg cttggtgaag cctctcttca
4921 cggaccctct ttctacagta aaatcagtaa attggtcata actgaactca aagaaggtgg
4981 gatggacttt tacgtgccaa ggcaggaacc catgttcagg tggatgaggt tttctgactt
5041 gagcacgtgg gagggcgatc gcaatctggc tcccaatttt gtgaatgaag atggcgtcga
5101 atgacgccgc tccatctaat gatggtgcag ccggtctcgt accagaggtc aacaatgaga
5161 ccatggcact tgaaccggtg gctggggctt cgatagccgc cccactcacc ggccaaaata
5221 atgttataga cccctggatt agattaaatt ttgtgcaggc ccctaatgga gagtttacag
5281 tctcaccccg caactcgcct ggggaagtcc tactcaattt ggaattaggt cccgaattga
5341 atccatattt ggcacacctt tctagaatgt ataatggtta tgcaggtgga gttgaagtgc
5401 aagtgctact ggctgggaac gcgttcacgg ctggaaaatt ggtatttgct gcagttcccc
5461 ctcattttcc attagagaat ataagccctg gtcaaataac catgttccct catgtaatta
5521 ttgatgttag gactttggaa ccagttttat tgcctctacc agatgtcaga aataacttct
5581 tccattacaa tcaacaaaat gagccgagga tgaggcttgt tgcaatgctt tatacccctc
5641 ttagatctaa tggttctggt gatgatgtgt tcaccgtctc ctgtagggtg ctcactcgac
5701 cctctcctga ttttgatttt aattatctgg tgcccccaac agttgaatct aaaacaaaac
5761 cattcacact ccctgtcttg accattgggg agttaaccaa ttccaggttc cctgtgccca
5821 tagatgaact ctacactagc cccaatgaga gtttggtggt tcaaccccag aacgggaggt
5881 gcgcgctgga tggggagttg cagggcacca cccagctcct tcccacggcg atttgctcgt
5941 tcaggggtcg gatcaatcag aaagtgagtg gagagaatca tgtttggaac atgcaagtca
6001 ccaacattaa cggaacccct tttgatccaa cagaggatgt tccagcccct ctgggcacgc
6061 cagacttttc tggcaagctc tttggtgtcc taagccagag ggaccatgat aatgcctgca
6121 ggagtcatga tgcagtgatt gcaactcatt ccaccaagtt taccccaaaa ttgggtgctg
6181 tacaaattgg cacgtgggaa caagatgatg tacacatcaa tcaacccacc aagtttactc
6241 cagttggatt gtttgagaat gaaggtttta atcaatggac acttcctaat tattctggag
6301 ctttaacact caatatgggg ttggcccccc ctgtggcccc cacatttcct ggtgagcaaa
6361 ttctcttctt caggtcccac attcccctta aaggaggtgt tgcagaccca gttattgatt
6421 gtcttctacc ccaagagtgg atccaacact tgtatcagga gtcagcccct tcacaaacag
6481 atgtggcact gattagattc acaaatccag acacagggcg tgtcctattt gaagcaaaat
6541 tgcacaggag tggctacatc acagtggcca acactggtag cagaccaatt gtggtgccag
6601 ctaatggtta tttcaggttt gactcttggg ttaatcagtt ttactctctt gcccccatgg
6661 gaactgggaa tgggcgcaga aggatgcagt aatggctgga gctttcatag cagggcttgc
6721 cggtgacata gtcaccaata gcattggctc actcgtgaac gctggggcca atgcaataaa
6781 ccagaaagta gactttgaaa acaacaagca actacaacag gcatctttca accatgacaa
6841 agagatgttg caagctcaaa ttcaggccac caaacagcta caggctgata tgattgcaat
6901 cagacaaggg gtgttgaccg caggcggctt ctcccctact gatgcagcaa gaggtgcagt
6961 caacgcgccc atgactcaag tcttggattg gaatgggacc agacattggg cccccggagc
7021 cacgaaaaca actgctttct ccggtgggtt taccagtgcc tctcatgcca ggaccgttga
7081 cctgaccaag aaaacatcag ccacaccagc ccctatgcct gtttctaggc ccagttctaa
7141 tgcttccact gtttctactc gctctacttt gattagtggg tcctctaatt ctcctgcttc
7201 agctaggagc tcttctagcg tttcttccca acccacttcc tcatcctccc gaactagtga
7261 gtgggtacgc agtcaaaata gggcgctgga gccttatatg aatggggcgc tgcgtacagc
7321 ctacgtgacg cctccatcca gtagggcttc tagcaatggc acagtctcaa ccgtgccaaa
7381 agaggttttg gactcctggt cgtctgcgtt caatacacac agacagccgc tgtttgctca
7441 tctccgtcgg agaggggagt cacaagctta gtgaaaagat
//